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Drug Class Breakdown for Different Databases

ARO

	Counts
Total descendants	602
Direct descendants	61
Intermediate nodes	33
Leaves	508

Other databases

ARG-ANNOT

Original ID	count
bla	1479
agly	193
mls	101
gly	88
flq	74
col	65
tet	60
phe	59
tmt	47
fcyn	30
oxzln	19
rif	9
ntmdz	7
fcd	5
sul	4
fus	1
agly_flqn	1
mupirocin	1
tetracenomycinc	1

Number of unique antibiotic classes: 19

DeepARG

Original ID	count
multidrug	4454
beta-lactam	2878
mls	1710
tetracycline	557
fosfomycin	434
aminoglycoside	403
glycopeptide	349
unclassified	313
bacitracin	280
polymyxin	245
fluoroquinolone	159
phenicol	155
sulfonamide	125
diaminopyrimidine	87
rifamycin	40
fosmidomycin	28
peptide	23
tetracenomycin_c	8
nucleoside	6
fusidic-acid	6
triclosan	4
aminocoumarin	3
fusaric-acid	2
antibacterial_free_fatty_acids	2
mupirocin	1
aminoglycoside:aminocoumarin	1
polyamine:peptide	1
acridine_dye	1
pleuromutilin	1
bicyclomycin	1
oxazolidinone	1
nitroimidazole	1

Number of unique antibiotic classes: 32

MEGARes

Original ID	count
betalactams	4599
aminoglycosides	800
fluoroquinolones	319
tetracyclines	301
glycopeptides	300
mls	297
drug_and_biocide_resistance	189
phenicol	150
trimethoprim	147
multi-drug_resistance	130
lipopeptides	109
sulfonamides	105
rifampin	74
fosfomycin	70
aminocoumarins	41
mycobacterium_tuberculosis-specific_drug	32
elfamycins	22
metronidazole	21
nucleosides	15
cationic_antimicrobial_peptides	13
fusidic_acid	11
bacitracin	6
drug_and_biocide_and_metal_resistance	6
mupirocin	5
multi-metal_resistance	5
oxazolidinone	4
phenolic_compound_resistance	4
mercury_resistance	4
pleuromutilin	4
thiopeptides	2
tellurium_resistance	2
spiropyrimidinetriones	1
tetracenomycin	1
pactamycin	1
biocide_and_metal_resistance	1
copper_resistance	1
aldehyde_resistance	1

Number of unique antibiotic classes: 37

NCBI

Original ID	count
beta-lactam	4579
	1026
aminoglycoside	695
tetracycline	241
glycopeptide	236
quinolone	139
phenicol	131
trimethoprim	127
colistin	116
stx2	113
macrolide	81
lincosamide/macrolide/streptogramin	80
efflux	71
fosfomycin	64
arsenic	52
mercury	48
phenicol/quinolone	43
intimin	43
sulfonamide	41
quaternary_ammonium	40
lincosamide	37
copper	26
rifamycin	21
stx1	20
streptogramin	19
lincosamide/macrolide	17
streptothricin	14
macrolide/streptogramin	13
nickel	12
nitroimidazole	10
aminoglycoside/quinolone	10
lincosamide/streptogramin	10
bleomycin	10
phenicol/lincosamide/oxazolidinone/pleuromutilin/streptogramin	9
tellurium	9
copper/silver	8
cadmium	7
lincosamide/pleuromutilin/streptogramin	7
fusidic_acid	7
phenicol/oxazolidinone	4
pleuromutilin	4
mupirocin	3
bacitracin	3
copper/nickel	2
thiostrepton	2
chromate	2
cadmium/cobalt/nickel	2
ionophore	2
silver	2
tuberactinomycin	2
macrolide/phenicol	1
cadmium/lead/zinc	1
tetracenomycin	1
fluoroquinolone	1
lincosamide/pleuromutilin	1
avilamycin	1
gold	1
copper/gold	1
aminoglycoside/phenicol	1
fluoride	1

Number of unique antibiotic classes: 60

SARG

Type	count
beta_lactam	4579
multidrug	3388
macrolide-lincosamide-streptogramin	1765
fosfomycin	454
aminoglycoside	406
tetracycline	388
quinolone	337
polymyxin	327
bacitracin	294
vancomycin	201
sulfonamide	133
trimethoprim	122
chloramphenicol	117
novobiocin	94
florfenicol	37
rifamycin	28
other_peptide_antibiotics	15
bleomycin	11
fusidic_acid	10
tetracenomycin_C	8
streptothricin	7
pleuromutilin_tiamulin	5
defensin	5
tunicamycin	4
puromycin	3
mupirocin	3
antibacterial_fatty_acid	2
bicyclomycin	1
factumycin	1
edeine	1

Number of unique antibiotic classes: 30

ResFinder

Class	count
Beta-lactam	2016
Aminoglycoside	261
Folate pathway antagonist	163
Tetracycline	161
Quinolone	126
Polymyxin	106
Macrolide, Lincosamide, Streptogramin B	80
Glycopeptide	46
Fosfomycin	42
Amphenicol	41
Macrolide	39
Oxazolidinone, Amphenicol	20
Nitroimidazole	14
Streptogramin A	14
Lincosamide, Streptogramin A, Pleuromutilin	13
Lincosamide	12
Rifamycin	10
Oxazolidinone, Amphenicol, Lincosamide, Streptogramin A, Pleuromutilin	7
Macrolide, Streptogramin B	7
Aminoglycoside, Quinolone	3
Steroid antibacterial	3
Pseudomonic acid	3
Lincosamide, Streptogramin A	3
Amphenicol, Oxazolidinone, Tetracycline	2
Streptogramin B	2
Amphenicol, Quinolone, Folate pathway antagonist	2
Ionophores	2
Pleuromutilin	1
Macrolide, Tetracycline	1
Streptogramin A, Streptogramin B	1
Macrolide, Lincosamide, Streptogramin A, Streptogramin B, Tetracycline	1
Macrolide, Lincosamide	1

Number of unique antibiotic classes: 32

ResFinderFG

1	count
TMP	1670
CYC	1403
TET	833
SXT	643
PEN	538
AMX	535
CHL	475
PIP	292
CAZ	251
AMP	241
GEN	175
ATM	163
TGC	156
FOX	74
CTX	57
CAR	55
AMC	54
TZP	52
KAN	45
FEP	33
CST	21
SPT	12
OXY	11
MIN	11
bLac	9
CDR	9
SIS	9
ERY	8
CEF	6
AZM	5
SMZ	5
TET/AMP	4
STX	4
SDX	4
MEM	3
STG	2
AMK	2
TYL	1
CIP	1
APR	1
STR	1
TZB	1

Number of unique antibiotic classes: 42