From 7bbf72a5379c599b53cebd46b0cbfbfa6eb63850 Mon Sep 17 00:00:00 2001 From: Peter van Heusden Date: Sun, 6 Aug 2023 22:17:15 +0200 Subject: [PATCH] Reformat with black, ensure flake8 passes --- .flake8 | 4 + src/tb_variant_filter/__init__.py | 2 - .../filters/alt_percentage_filter.py | 30 +- .../filters/close_to_indel_filter.py | 5 +- .../filters/min_depth_filter.py | 4 +- .../masks/farhat_rlc_lowmap.py | 2652 ++++++++--------- src/tb_variant_filter/masks/mtbseq.py | 25 +- src/tb_variant_filter/masks/tbprofiler.py | 130 +- src/tb_variant_filter/masks/uvp.py | 2 +- src/tb_variant_filter/region_list.py | 26 +- src/tb_variant_filter/regions_to_bed.py | 8 +- src/tests/test_farhat_rlc.py | 2 + src/tests/test_farhat_rlc_lowmap.py | 6 +- src/tests/test_uvp.py | 2 + 14 files changed, 1474 insertions(+), 1424 deletions(-) create mode 100644 .flake8 diff --git a/.flake8 b/.flake8 new file mode 100644 index 0000000..6b509d2 --- /dev/null +++ b/.flake8 @@ -0,0 +1,4 @@ +[flake8] +max-line-length = 80 +select = C,E,F,W,B,B950 +ignore = E501 diff --git a/src/tb_variant_filter/__init__.py b/src/tb_variant_filter/__init__.py index 8d99c9d..667fb9f 100644 --- a/src/tb_variant_filter/__init__.py +++ b/src/tb_variant_filter/__init__.py @@ -58,7 +58,6 @@ def __get__(self, obj, cls): return self.get_no_inst(cls) def get_with_inst(self, obj, cls): - overridden = getattr(super(cls, obj), self.name, None) @wraps(self.mthd, assigned=("__name__", "__module__")) @@ -68,7 +67,6 @@ def f(*args, **kwargs): return self.use_parent_doc(f, overridden) def get_no_inst(self, cls): - for parent in cls.__mro__[1:]: overridden = getattr(parent, self.name, None) if overridden: diff --git a/src/tb_variant_filter/filters/alt_percentage_filter.py b/src/tb_variant_filter/filters/alt_percentage_filter.py index 38bf136..6f3fb37 100644 --- a/src/tb_variant_filter/filters/alt_percentage_filter.py +++ b/src/tb_variant_filter/filters/alt_percentage_filter.py @@ -24,7 +24,9 @@ class AltPercentageDepthFilter(Filter): min_percentage = 0 - def __init__(self, args: argparse.Namespace, header: vcfpy.Header) -> "AltPercentageDepthFilter": + def __init__( + self, args: argparse.Namespace, header: vcfpy.Header + ) -> "AltPercentageDepthFilter": super().__init__(args, header) if ( hasattr(args, "min_percentage_alt_filter") @@ -71,34 +73,46 @@ def __call__(self, record: vcfpy.Record) -> Union[vcfpy.Record, None]: alt_percentage = record.INFO["AF1"] * 100 elif self.header.has_header_line("INFO", "DP4"): (fwd_ref, rev_ref, fwd_alt, rev_alt) = record.INFO["DP4"] - alt_percentage = (fwd_alt + rev_alt) / (fwd_ref + rev_ref + fwd_alt + rev_alt) * 100 + alt_percentage = ( + (fwd_alt + rev_alt) / (fwd_ref + rev_ref + fwd_alt + rev_alt) * 100 + ) if alt_percentage is not None: retain.append(not alt_percentage < self.min_percentage) - elif self.header.has_header_line("INFO", "AF") or (self.header.has_header_line("INFO", "AO") and self.header.has_header_line("INFO", "DP")): + elif self.header.has_header_line("INFO", "AF") or ( + self.header.has_header_line("INFO", "AO") + and self.header.has_header_line("INFO", "DP") # noqa: W503 + ): for i, _ in enumerate(record.ALT): if self.header.has_header_line("INFO", "AF"): alt_percentage = record.INFO["AF"][i] * 100 - elif self.header.has_header_line("INFO", "AO") and self.header.has_header_line("INFO", "DP"): + elif self.header.has_header_line( + "INFO", "AO" + ) and self.header.has_header_line("INFO", "DP"): alt_percentage = ( float(record.INFO["AO"][i]) / float(record.INFO["DP"]) * 100 ) retain.append(not alt_percentage < self.min_percentage) else: # we've got nothing to add to retain - leave it as an empty list - print("No alt allele depth information found in VCF, disabling alt allele percentage filter", file=sys.stderr) + print( + "No alt allele depth information found in VCF, disabling alt allele percentage filter", + file=sys.stderr, + ) if not any(retain): return None - + new_ALT = [alt for i, alt in enumerate(record.ALT) if retain[i]] new_INFO = OrderedDict() # these are produced by snpEff and keys occur once per implicated gene # the simplest solution is to copy them all across for key in record.INFO: - if self.header.get_info_field_info(key).number == 'A': + if self.header.get_info_field_info(key).number == "A": # 'A' fields have one entry for each alternative allele - copy only those for retained alleles field_len = len(record.INFO[key]) retain_len = len(retain) - assert field_len == retain_len, f"Length of array-type INFO field ({field_len}) does not match length of retain ({retain_len})" + assert ( + field_len == retain_len + ), f"Length of array-type INFO field ({field_len}) does not match length of retain ({retain_len})" new_INFO[key] = [ # retain all ANN records and the only those other records that correspond to alts that we retain el diff --git a/src/tb_variant_filter/filters/close_to_indel_filter.py b/src/tb_variant_filter/filters/close_to_indel_filter.py index d42d5c2..97d1b48 100644 --- a/src/tb_variant_filter/filters/close_to_indel_filter.py +++ b/src/tb_variant_filter/filters/close_to_indel_filter.py @@ -25,7 +25,9 @@ class CloseToIndelFilter(Filter): intervaltree = None dist = 0 - def __init__(self, args: argparse.Namespace, header: Header) -> "CloseToIndelFilter": + def __init__( + self, args: argparse.Namespace, header: Header + ) -> "CloseToIndelFilter": super().__init__(args, header) self.intervaltree = IntervalTree() if hasattr(args, "close_to_indel_filter") and args.close_to_indel_filter: @@ -50,7 +52,6 @@ def __init__(self, args: argparse.Namespace, header: Header) -> "CloseToIndelFil args.input_file.seek(0) def __repr__(self) -> str: - name = f"{self.__class__.__name__}" if self.dist: name += f" (Window {self.dist})" diff --git a/src/tb_variant_filter/filters/min_depth_filter.py b/src/tb_variant_filter/filters/min_depth_filter.py index 232ac9e..b4485c7 100644 --- a/src/tb_variant_filter/filters/min_depth_filter.py +++ b/src/tb_variant_filter/filters/min_depth_filter.py @@ -22,7 +22,9 @@ class MinDepthFilter(Filter): min_depth = 0 - def __init__(self, args: argparse.Namespace, header: vcfpy.Header) -> "MinDepthFilter": + def __init__( + self, args: argparse.Namespace, header: vcfpy.Header + ) -> "MinDepthFilter": super().__init__(args, header) if ( hasattr(args, "min_depth_filter") diff --git a/src/tb_variant_filter/masks/farhat_rlc_lowmap.py b/src/tb_variant_filter/masks/farhat_rlc_lowmap.py index 7600b8b..6923788 100644 --- a/src/tb_variant_filter/masks/farhat_rlc_lowmap.py +++ b/src/tb_variant_filter/masks/farhat_rlc_lowmap.py @@ -1,4 +1,3 @@ - # Copyright (C) 2022 Peter van Heusden # # This program is free software: you can redistribute it and/or modify @@ -20,7 +19,6 @@ from ..region_list import RegionList, bed_to_regions -from ..region_list import RegionList, bed_to_regions # noinspection PyPep8Naming class FarhatLab_RLC_LowMap_Regions(RegionList): @@ -29,1331 +27,1331 @@ class FarhatLab_RLC_LowMap_Regions(RegionList): description = "Refined Low Confidence and low mappability from Farhat Lab" # these regions are in the AF14_RLC_Regions.Plus.LowPmapK50E4.H37Rv.bed supplementary file in the publication project_url = "https://doi.org/10.1093/bioinformatics/btac023" - regions = [ - Location(locus='region1', start=23173, end=23238, strand=1), - Location(locus='region2', start=24720, end=24738, strand=1), - Location(locus='region3', start=39029, end=39030, strand=1), - Location(locus='region4', start=55548, end=55647, strand=1), - Location(locus='region5', start=71464, end=71584, strand=1), - Location(locus='region6', start=79499, end=83035, strand=1), - Location(locus='region7', start=86778, end=86779, strand=1), - Location(locus='region8', start=86780, end=86782, strand=1), - Location(locus='region9', start=103702, end=104811, strand=1), - Location(locus='region10', start=104813, end=105137, strand=1), - Location(locus='region11', start=131785, end=131844, strand=1), - Location(locus='region12', start=131928, end=131979, strand=1), - Location(locus='region13', start=131980, end=131982, strand=1), - Location(locus='region14', start=131992, end=131993, strand=1), - Location(locus='region15', start=132077, end=132079, strand=1), - Location(locus='region16', start=132159, end=132189, strand=1), - Location(locus='region17', start=132518, end=132684, strand=1), - Location(locus='region18', start=149499, end=149526, strand=1), - Location(locus='region19', start=149634, end=149760, strand=1), - Location(locus='region20', start=149825, end=150890, strand=1), - Location(locus='region21', start=154109, end=154245, strand=1), - Location(locus='region22', start=157278, end=157331, strand=1), - Location(locus='region23', start=157382, end=157433, strand=1), - Location(locus='region24', start=161526, end=161577, strand=1), - Location(locus='region25', start=171456, end=171457, strand=1), - Location(locus='region26', start=171778, end=171779, strand=1), - Location(locus='region27', start=177094, end=177180, strand=1), - Location(locus='region28', start=177225, end=177322, strand=1), - Location(locus='region29', start=177337, end=177408, strand=1), - Location(locus='region30', start=192336, end=192398, strand=1), - Location(locus='region31', start=197077, end=197130, strand=1), - Location(locus='region32', start=197191, end=197311, strand=1), - Location(locus='region33', start=197837, end=198006, strand=1), - Location(locus='region34', start=198089, end=198170, strand=1), - Location(locus='region35', start=198477, end=198537, strand=1), - Location(locus='region36', start=198936, end=199041, strand=1), - Location(locus='region37', start=199750, end=199832, strand=1), - Location(locus='region38', start=201952, end=202014, strand=1), - Location(locus='region39', start=206494, end=206519, strand=1), - Location(locus='region40', start=234446, end=234492, strand=1), - Location(locus='region41', start=253598, end=253666, strand=1), - Location(locus='region42', start=267757, end=267812, strand=1), - Location(locus='region43', start=272848, end=272957, strand=1), - Location(locus='region44', start=279525, end=279601, strand=1), - Location(locus='region45', start=293724, end=293792, strand=1), - Location(locus='region46', start=294285, end=294337, strand=1), - Location(locus='region47', start=308321, end=308413, strand=1), - Location(locus='region48', start=309084, end=309191, strand=1), - Location(locus='region49', start=309927, end=310110, strand=1), - Location(locus='region50', start=332699, end=333141, strand=1), - Location(locus='region51', start=333157, end=333223, strand=1), - Location(locus='region52', start=333292, end=333406, strand=1), - Location(locus='region53', start=333436, end=336385, strand=1), - Location(locus='region54', start=336399, end=336400, strand=1), - Location(locus='region55', start=336402, end=336403, strand=1), - Location(locus='region56', start=336404, end=336405, strand=1), - Location(locus='region57', start=336496, end=336497, strand=1), - Location(locus='region58', start=336503, end=336504, strand=1), - Location(locus='region59', start=336534, end=336535, strand=1), - Location(locus='region60', start=336536, end=336537, strand=1), - Location(locus='region61', start=336539, end=336540, strand=1), - Location(locus='region62', start=336545, end=336546, strand=1), - Location(locus='region63', start=336552, end=337173, strand=1), - Location(locus='region64', start=337265, end=337381, strand=1), - Location(locus='region65', start=337492, end=337617, strand=1), - Location(locus='region66', start=337714, end=339148, strand=1), - Location(locus='region67', start=339715, end=339822, strand=1), - Location(locus='region68', start=340429, end=340470, strand=1), - Location(locus='region69', start=340472, end=340484, strand=1), - Location(locus='region70', start=341205, end=341267, strand=1), - Location(locus='region71', start=350296, end=350360, strand=1), - Location(locus='region72', start=351570, end=351659, strand=1), - Location(locus='region73', start=351890, end=351940, strand=1), - Location(locus='region74', start=361634, end=361726, strand=1), - Location(locus='region75', start=361740, end=361973, strand=1), - Location(locus='region76', start=361987, end=362010, strand=1), - Location(locus='region77', start=362620, end=362748, strand=1), - Location(locus='region78', start=362751, end=362764, strand=1), - Location(locus='region79', start=362769, end=362916, strand=1), - Location(locus='region80', start=362960, end=363020, strand=1), - Location(locus='region81', start=366149, end=372764, strand=1), - Location(locus='region82', start=372777, end=372834, strand=1), - Location(locus='region83', start=373194, end=373249, strand=1), - Location(locus='region84', start=373280, end=373372, strand=1), - Location(locus='region85', start=373394, end=373471, strand=1), - Location(locus='region86', start=373527, end=373657, strand=1), - Location(locus='region87', start=373972, end=374026, strand=1), - Location(locus='region88', start=374051, end=374185, strand=1), - Location(locus='region89', start=374464, end=374983, strand=1), - Location(locus='region90', start=375259, end=375329, strand=1), - Location(locus='region91', start=400147, end=401706, strand=1), - Location(locus='region92', start=410552, end=410570, strand=1), - Location(locus='region93', start=424007, end=424150, strand=1), - Location(locus='region94', start=424843, end=425033, strand=1), - Location(locus='region95', start=425096, end=425154, strand=1), - Location(locus='region96', start=425168, end=425272, strand=1), - Location(locus='region97', start=425284, end=425410, strand=1), - Location(locus='region98', start=425411, end=425593, strand=1), - Location(locus='region99', start=426576, end=426680, strand=1), - Location(locus='region100', start=426736, end=426861, strand=1), - Location(locus='region101', start=426910, end=426998, strand=1), - Location(locus='region102', start=427070, end=427200, strand=1), - Location(locus='region103', start=427296, end=427383, strand=1), - Location(locus='region104', start=428403, end=428503, strand=1), - Location(locus='region105', start=428525, end=428762, strand=1), - Location(locus='region106', start=429119, end=429181, strand=1), - Location(locus='region107', start=429632, end=429716, strand=1), - Location(locus='region108', start=429791, end=430174, strand=1), - Location(locus='region109', start=431043, end=431094, strand=1), - Location(locus='region110', start=431126, end=431184, strand=1), - Location(locus='region111', start=431192, end=431263, strand=1), - Location(locus='region112', start=431273, end=431442, strand=1), - Location(locus='region113', start=431454, end=431551, strand=1), - Location(locus='region114', start=431884, end=431935, strand=1), - Location(locus='region115', start=432375, end=432436, strand=1), - Location(locus='region116', start=432533, end=432592, strand=1), - Location(locus='region117', start=432605, end=432804, strand=1), - Location(locus='region118', start=433691, end=433801, strand=1), - Location(locus='region119', start=433848, end=433930, strand=1), - Location(locus='region120', start=433940, end=434006, strand=1), - Location(locus='region121', start=434227, end=434311, strand=1), - Location(locus='region122', start=456207, end=456210, strand=1), - Location(locus='region123', start=456211, end=456212, strand=1), - Location(locus='region124', start=459877, end=459930, strand=1), - Location(locus='region125', start=460997, end=461069, strand=1), - Location(locus='region126', start=461350, end=461432, strand=1), - Location(locus='region127', start=472443, end=472496, strand=1), - Location(locus='region128', start=473741, end=474045, strand=1), - Location(locus='region129', start=474047, end=474109, strand=1), - Location(locus='region130', start=475807, end=476111, strand=1), - Location(locus='region131', start=476125, end=476183, strand=1), - Location(locus='region132', start=488167, end=488222, strand=1), - Location(locus='region133', start=496254, end=496354, strand=1), - Location(locus='region134', start=531536, end=531591, strand=1), - Location(locus='region135', start=538775, end=538840, strand=1), - Location(locus='region136', start=543555, end=543639, strand=1), - Location(locus='region137', start=560891, end=560941, strand=1), - Location(locus='region138', start=561274, end=561339, strand=1), - Location(locus='region139', start=561532, end=561658, strand=1), - Location(locus='region140', start=562303, end=562397, strand=1), - Location(locus='region141', start=566271, end=566345, strand=1), - Location(locus='region142', start=569811, end=569985, strand=1), - Location(locus='region143', start=577281, end=577503, strand=1), - Location(locus='region144', start=580566, end=580821, strand=1), - Location(locus='region145', start=594517, end=594569, strand=1), - Location(locus='region146', start=595330, end=595453, strand=1), - Location(locus='region147', start=598879, end=598932, strand=1), - Location(locus='region148', start=606506, end=608064, strand=1), - Location(locus='region149', start=622890, end=622945, strand=1), - Location(locus='region150', start=623098, end=624417, strand=1), - Location(locus='region151', start=631282, end=631440, strand=1), - Location(locus='region152', start=642735, end=642818, strand=1), - Location(locus='region153', start=663428, end=663429, strand=1), - Location(locus='region154', start=669263, end=669314, strand=1), - Location(locus='region155', start=672009, end=672011, strand=1), - Location(locus='region156', start=672014, end=672070, strand=1), - Location(locus='region157', start=672104, end=672108, strand=1), - Location(locus='region158', start=672161, end=672246, strand=1), - Location(locus='region159', start=672265, end=672274, strand=1), - Location(locus='region160', start=672443, end=672462, strand=1), - Location(locus='region161', start=672477, end=672524, strand=1), - Location(locus='region162', start=672532, end=672563, strand=1), - Location(locus='region163', start=672648, end=672805, strand=1), - Location(locus='region164', start=672827, end=672919, strand=1), - Location(locus='region165', start=672945, end=672951, strand=1), - Location(locus='region166', start=672955, end=672959, strand=1), - Location(locus='region167', start=673102, end=673134, strand=1), - Location(locus='region168', start=673135, end=673623, strand=1), - Location(locus='region169', start=673635, end=673637, strand=1), - Location(locus='region170', start=673647, end=673668, strand=1), - Location(locus='region171', start=673940, end=673995, strand=1), - Location(locus='region172', start=674121, end=674132, strand=1), - Location(locus='region173', start=674142, end=674163, strand=1), - Location(locus='region174', start=674218, end=674220, strand=1), - Location(locus='region175', start=674227, end=674233, strand=1), - Location(locus='region176', start=674240, end=674272, strand=1), - Location(locus='region177', start=674311, end=674319, strand=1), - Location(locus='region178', start=674343, end=674358, strand=1), - Location(locus='region179', start=674434, end=674507, strand=1), - Location(locus='region180', start=674546, end=674556, strand=1), - Location(locus='region181', start=674780, end=675029, strand=1), - Location(locus='region182', start=675034, end=675405, strand=1), - Location(locus='region183', start=675486, end=675548, strand=1), - Location(locus='region184', start=675555, end=675615, strand=1), - Location(locus='region185', start=677064, end=677128, strand=1), - Location(locus='region186', start=685345, end=685398, strand=1), - Location(locus='region187', start=685459, end=685579, strand=1), - Location(locus='region188', start=686123, end=686292, strand=1), - Location(locus='region189', start=686375, end=686456, strand=1), - Location(locus='region190', start=686763, end=686823, strand=1), - Location(locus='region191', start=687245, end=687325, strand=1), - Location(locus='region192', start=687887, end=687969, strand=1), - Location(locus='region193', start=690079, end=690141, strand=1), - Location(locus='region194', start=699610, end=699640, strand=1), - Location(locus='region195', start=701242, end=701311, strand=1), - Location(locus='region196', start=701313, end=701438, strand=1), - Location(locus='region197', start=702055, end=702169, strand=1), - Location(locus='region198', start=702279, end=702358, strand=1), - Location(locus='region199', start=702538, end=702627, strand=1), - Location(locus='region200', start=709420, end=709489, strand=1), - Location(locus='region201', start=709492, end=709544, strand=1), - Location(locus='region202', start=709581, end=709666, strand=1), - Location(locus='region203', start=711563, end=711705, strand=1), - Location(locus='region204', start=716627, end=716678, strand=1), - Location(locus='region205', start=717242, end=717295, strand=1), - Location(locus='region206', start=717640, end=717717, strand=1), - Location(locus='region207', start=718309, end=718366, strand=1), - Location(locus='region208', start=718811, end=718863, strand=1), - Location(locus='region209', start=718864, end=718926, strand=1), - Location(locus='region210', start=719128, end=719200, strand=1), - Location(locus='region211', start=719383, end=719465, strand=1), - Location(locus='region212', start=719466, end=719546, strand=1), - Location(locus='region213', start=719637, end=719688, strand=1), - Location(locus='region214', start=725208, end=725233, strand=1), - Location(locus='region215', start=735079, end=735081, strand=1), - Location(locus='region216', start=736226, end=736298, strand=1), - Location(locus='region217', start=737308, end=737390, strand=1), - Location(locus='region218', start=737989, end=738061, strand=1), - Location(locus='region219', start=738337, end=738419, strand=1), - Location(locus='region220', start=738723, end=738788, strand=1), - Location(locus='region221', start=738922, end=738974, strand=1), - Location(locus='region222', start=738981, end=739052, strand=1), - Location(locus='region223', start=739053, end=739144, strand=1), - Location(locus='region224', start=742562, end=742638, strand=1), - Location(locus='region225', start=747949, end=748000, strand=1), - Location(locus='region226', start=755259, end=755331, strand=1), - Location(locus='region227', start=767365, end=767366, strand=1), - Location(locus='region228', start=767367, end=767371, strand=1), - Location(locus='region229', start=776715, end=776768, strand=1), - Location(locus='region230', start=786025, end=786081, strand=1), - Location(locus='region231', start=795468, end=795527, strand=1), - Location(locus='region232', start=798663, end=798739, strand=1), - Location(locus='region233', start=798998, end=799069, strand=1), - Location(locus='region234', start=806193, end=806194, strand=1), - Location(locus='region235', start=806195, end=806199, strand=1), - Location(locus='region236', start=806202, end=806219, strand=1), - Location(locus='region237', start=812848, end=812898, strand=1), - Location(locus='region238', start=818308, end=818358, strand=1), - Location(locus='region239', start=829702, end=829773, strand=1), - Location(locus='region240', start=830629, end=830685, strand=1), - Location(locus='region241', start=830712, end=830765, strand=1), - Location(locus='region242', start=831188, end=831263, strand=1), - Location(locus='region243', start=831965, end=832028, strand=1), - Location(locus='region244', start=832083, end=832362, strand=1), - Location(locus='region245', start=832654, end=832758, strand=1), - Location(locus='region246', start=832980, end=833508, strand=1), - Location(locus='region247', start=833514, end=833517, strand=1), - Location(locus='region248', start=833529, end=833539, strand=1), - Location(locus='region249', start=835080, end=835203, strand=1), - Location(locus='region250', start=835405, end=835458, strand=1), - Location(locus='region251', start=835700, end=838052, strand=1), - Location(locus='region252', start=838450, end=840856, strand=1), - Location(locus='region253', start=840959, end=841073, strand=1), - Location(locus='region254', start=841142, end=841208, strand=1), - Location(locus='region255', start=841224, end=841666, strand=1), - Location(locus='region256', start=841941, end=842016, strand=1), - Location(locus='region257', start=842058, end=842470, strand=1), - Location(locus='region258', start=844884, end=844888, strand=1), - Location(locus='region259', start=846903, end=846905, strand=1), - Location(locus='region260', start=849912, end=849965, strand=1), - Location(locus='region261', start=863185, end=863260, strand=1), - Location(locus='region262', start=888762, end=891466, strand=1), - Location(locus='region263', start=908176, end=909351, strand=1), - Location(locus='region264', start=917606, end=917740, strand=1), - Location(locus='region265', start=921573, end=921897, strand=1), - Location(locus='region266', start=925070, end=925133, strand=1), - Location(locus='region267', start=925262, end=926393, strand=1), - Location(locus='region268', start=926515, end=926596, strand=1), - Location(locus='region269', start=926626, end=927518, strand=1), - Location(locus='region270', start=927890, end=927940, strand=1), - Location(locus='region271', start=928675, end=928791, strand=1), - Location(locus='region272', start=928868, end=928936, strand=1), - Location(locus='region273', start=929015, end=929360, strand=1), - Location(locus='region274', start=929367, end=929373, strand=1), - Location(locus='region275', start=929463, end=929470, strand=1), - Location(locus='region276', start=929476, end=929605, strand=1), - Location(locus='region277', start=929666, end=929961, strand=1), - Location(locus='region278', start=958454, end=958522, strand=1), - Location(locus='region279', start=960161, end=960332, strand=1), - Location(locus='region280', start=964577, end=965082, strand=1), - Location(locus='region281', start=968779, end=968829, strand=1), - Location(locus='region282', start=969615, end=969752, strand=1), - Location(locus='region283', start=969874, end=969934, strand=1), - Location(locus='region284', start=972605, end=972657, strand=1), - Location(locus='region285', start=972658, end=972720, strand=1), - Location(locus='region286', start=972922, end=972994, strand=1), - Location(locus='region287', start=973177, end=973259, strand=1), - Location(locus='region288', start=973260, end=973340, strand=1), - Location(locus='region289', start=973431, end=973482, strand=1), - Location(locus='region290', start=973762, end=973786, strand=1), - Location(locus='region291', start=976897, end=976913, strand=1), - Location(locus='region292', start=977517, end=977570, strand=1), - Location(locus='region293', start=977979, end=978031, strand=1), - Location(locus='region294', start=978087, end=978143, strand=1), - Location(locus='region295', start=996027, end=996089, strand=1), - Location(locus='region296', start=1000741, end=1000799, strand=1), - Location(locus='region297', start=1025867, end=1025899, strand=1), - Location(locus='region298', start=1025901, end=1025904, strand=1), - Location(locus='region299', start=1056823, end=1056824, strand=1), - Location(locus='region300', start=1056825, end=1056829, strand=1), - Location(locus='region301', start=1064047, end=1064118, strand=1), - Location(locus='region302', start=1066998, end=1067002, strand=1), - Location(locus='region303', start=1070325, end=1070330, strand=1), - Location(locus='region304', start=1071258, end=1071318, strand=1), - Location(locus='region305', start=1090782, end=1090783, strand=1), - Location(locus='region306', start=1090788, end=1090789, strand=1), - Location(locus='region307', start=1090790, end=1090793, strand=1), - Location(locus='region308', start=1090803, end=1090814, strand=1), - Location(locus='region309', start=1090938, end=1090940, strand=1), - Location(locus='region310', start=1090957, end=1091137, strand=1), - Location(locus='region311', start=1091147, end=1091152, strand=1), - Location(locus='region312', start=1091362, end=1091368, strand=1), - Location(locus='region313', start=1091373, end=1091379, strand=1), - Location(locus='region314', start=1091388, end=1091846, strand=1), - Location(locus='region315', start=1091888, end=1092021, strand=1), - Location(locus='region316', start=1092056, end=1092089, strand=1), - Location(locus='region317', start=1092102, end=1092104, strand=1), - Location(locus='region318', start=1092246, end=1092263, strand=1), - Location(locus='region319', start=1093232, end=1093320, strand=1), - Location(locus='region320', start=1093450, end=1093647, strand=1), - Location(locus='region321', start=1093650, end=1094593, strand=1), - Location(locus='region322', start=1094865, end=1094953, strand=1), - Location(locus='region323', start=1095203, end=1095325, strand=1), - Location(locus='region324', start=1095331, end=1096699, strand=1), - Location(locus='region325', start=1121040, end=1121090, strand=1), - Location(locus='region326', start=1121121, end=1121171, strand=1), - Location(locus='region327', start=1121657, end=1121731, strand=1), - Location(locus='region328', start=1133280, end=1133283, strand=1), - Location(locus='region329', start=1145287, end=1145317, strand=1), - Location(locus='region330', start=1159195, end=1159245, strand=1), - Location(locus='region331', start=1160331, end=1160421, strand=1), - Location(locus='region332', start=1160537, end=1161159, strand=1), - Location(locus='region333', start=1161301, end=1161365, strand=1), - Location(locus='region334', start=1162562, end=1162612, strand=1), - Location(locus='region335', start=1164564, end=1165555, strand=1), - Location(locus='region336', start=1169292, end=1170739, strand=1), - Location(locus='region337', start=1179346, end=1179397, strand=1), - Location(locus='region338', start=1182321, end=1182382, strand=1), - Location(locus='region339', start=1188518, end=1188908, strand=1), - Location(locus='region340', start=1188949, end=1188955, strand=1), - Location(locus='region341', start=1188972, end=1189047, strand=1), - Location(locus='region342', start=1189073, end=1189075, strand=1), - Location(locus='region343', start=1189081, end=1189157, strand=1), - Location(locus='region344', start=1189158, end=1190177, strand=1), - Location(locus='region345', start=1190249, end=1190299, strand=1), - Location(locus='region346', start=1190854, end=1190944, strand=1), - Location(locus='region347', start=1190969, end=1191112, strand=1), - Location(locus='region348', start=1191130, end=1191221, strand=1), - Location(locus='region349', start=1191248, end=1191901, strand=1), - Location(locus='region350', start=1200523, end=1200544, strand=1), - Location(locus='region351', start=1203334, end=1203396, strand=1), - Location(locus='region352', start=1211559, end=1213863, strand=1), - Location(locus='region353', start=1216548, end=1216649, strand=1), - Location(locus='region354', start=1216717, end=1216769, strand=1), - Location(locus='region355', start=1216817, end=1216921, strand=1), - Location(locus='region356', start=1216922, end=1217162, strand=1), - Location(locus='region357', start=1217167, end=1217181, strand=1), - Location(locus='region358', start=1217416, end=1217422, strand=1), - Location(locus='region359', start=1217423, end=1218426, strand=1), - Location(locus='region360', start=1218436, end=1218676, strand=1), - Location(locus='region361', start=1218702, end=1218703, strand=1), - Location(locus='region362', start=1218968, end=1218970, strand=1), - Location(locus='region363', start=1224338, end=1224340, strand=1), - Location(locus='region364', start=1224341, end=1224345, strand=1), - Location(locus='region365', start=1224348, end=1224350, strand=1), - Location(locus='region366', start=1224356, end=1224357, strand=1), - Location(locus='region367', start=1230571, end=1230648, strand=1), - Location(locus='region368', start=1251678, end=1251752, strand=1), - Location(locus='region369', start=1262918, end=1263031, strand=1), - Location(locus='region370', start=1263084, end=1263190, strand=1), - Location(locus='region371', start=1263707, end=1263760, strand=1), - Location(locus='region372', start=1267219, end=1267269, strand=1), - Location(locus='region373', start=1275555, end=1275607, strand=1), - Location(locus='region374', start=1275922, end=1276056, strand=1), - Location(locus='region375', start=1276289, end=1278829, strand=1), - Location(locus='region376', start=1281895, end=1282022, strand=1), - Location(locus='region377', start=1283487, end=1283493, strand=1), - Location(locus='region378', start=1283512, end=1283548, strand=1), - Location(locus='region379', start=1283554, end=1283562, strand=1), - Location(locus='region380', start=1284407, end=1284473, strand=1), - Location(locus='region381', start=1284491, end=1284557, strand=1), - Location(locus='region382', start=1287559, end=1287627, strand=1), - Location(locus='region383', start=1287810, end=1288095, strand=1), - Location(locus='region384', start=1293002, end=1293070, strand=1), - Location(locus='region385', start=1305490, end=1305665, strand=1), - Location(locus='region386', start=1313129, end=1313134, strand=1), - Location(locus='region387', start=1313384, end=1313385, strand=1), - Location(locus='region388', start=1313389, end=1313394, strand=1), - Location(locus='region389', start=1319185, end=1319262, strand=1), - Location(locus='region390', start=1326283, end=1326333, strand=1), - Location(locus='region391', start=1335476, end=1335507, strand=1), - Location(locus='region392', start=1335508, end=1335513, strand=1), - Location(locus='region393', start=1339343, end=1339839, strand=1), - Location(locus='region394', start=1339886, end=1340001, strand=1), - Location(locus='region395', start=1340006, end=1340060, strand=1), - Location(locus='region396', start=1340061, end=1340397, strand=1), - Location(locus='region397', start=1340491, end=1342739, strand=1), - Location(locus='region398', start=1351194, end=1351283, strand=1), - Location(locus='region399', start=1357060, end=1357129, strand=1), - Location(locus='region400', start=1357247, end=1357302, strand=1), - Location(locus='region401', start=1363470, end=1363471, strand=1), - Location(locus='region402', start=1385096, end=1385437, strand=1), - Location(locus='region403', start=1385572, end=1385580, strand=1), - Location(locus='region404', start=1385586, end=1385667, strand=1), - Location(locus='region405', start=1385669, end=1385672, strand=1), - Location(locus='region406', start=1386008, end=1386036, strand=1), - Location(locus='region407', start=1386073, end=1386081, strand=1), - Location(locus='region408', start=1386112, end=1386113, strand=1), - Location(locus='region409', start=1386118, end=1386121, strand=1), - Location(locus='region410', start=1386125, end=1386129, strand=1), - Location(locus='region411', start=1386136, end=1386140, strand=1), - Location(locus='region412', start=1386154, end=1386214, strand=1), - Location(locus='region413', start=1386285, end=1386359, strand=1), - Location(locus='region414', start=1386451, end=1386501, strand=1), - Location(locus='region415', start=1388110, end=1388170, strand=1), - Location(locus='region416', start=1408678, end=1408729, strand=1), - Location(locus='region417', start=1414620, end=1414621, strand=1), - Location(locus='region418', start=1414628, end=1414629, strand=1), - Location(locus='region419', start=1414643, end=1414644, strand=1), - Location(locus='region420', start=1414652, end=1414653, strand=1), - Location(locus='region421', start=1441364, end=1441725, strand=1), - Location(locus='region422', start=1443427, end=1443428, strand=1), - Location(locus='region423', start=1443433, end=1443486, strand=1), - Location(locus='region424', start=1445086, end=1445117, strand=1), - Location(locus='region425', start=1445118, end=1445121, strand=1), - Location(locus='region426', start=1451772, end=1452003, strand=1), - Location(locus='region427', start=1456572, end=1456625, strand=1), - Location(locus='region428', start=1457459, end=1457568, strand=1), - Location(locus='region429', start=1468160, end=1469623, strand=1), - Location(locus='region430', start=1479348, end=1479409, strand=1), - Location(locus='region431', start=1479487, end=1479538, strand=1), - Location(locus='region432', start=1479716, end=1479925, strand=1), - Location(locus='region433', start=1480944, end=1480945, strand=1), - Location(locus='region434', start=1480947, end=1481670, strand=1), - Location(locus='region435', start=1482823, end=1482878, strand=1), - Location(locus='region436', start=1483109, end=1483165, strand=1), - Location(locus='region437', start=1483196, end=1483254, strand=1), - Location(locus='region438', start=1483264, end=1483318, strand=1), - Location(locus='region439', start=1488082, end=1488147, strand=1), - Location(locus='region440', start=1488383, end=1488410, strand=1), - Location(locus='region441', start=1488413, end=1488420, strand=1), - Location(locus='region442', start=1488429, end=1488757, strand=1), - Location(locus='region443', start=1488760, end=1488766, strand=1), - Location(locus='region444', start=1488776, end=1488788, strand=1), - Location(locus='region445', start=1488791, end=1488794, strand=1), - Location(locus='region446', start=1488807, end=1488810, strand=1), - Location(locus='region447', start=1488813, end=1488839, strand=1), - Location(locus='region448', start=1488843, end=1488848, strand=1), - Location(locus='region449', start=1488896, end=1489512, strand=1), - Location(locus='region450', start=1489537, end=1489647, strand=1), - Location(locus='region451', start=1489738, end=1489798, strand=1), - Location(locus='region452', start=1524571, end=1524574, strand=1), - Location(locus='region453', start=1532535, end=1532922, strand=1), - Location(locus='region454', start=1532986, end=1533658, strand=1), - Location(locus='region455', start=1541944, end=1543431, strand=1), - Location(locus='region456', start=1543453, end=1543457, strand=1), - Location(locus='region457', start=1543462, end=1543480, strand=1), - Location(locus='region458', start=1568048, end=1568106, strand=1), - Location(locus='region459', start=1572184, end=1572482, strand=1), - Location(locus='region460', start=1572499, end=1572621, strand=1), - Location(locus='region461', start=1572744, end=1573530, strand=1), - Location(locus='region462', start=1573555, end=1573606, strand=1), - Location(locus='region463', start=1606514, end=1606565, strand=1), - Location(locus='region464', start=1612562, end=1612665, strand=1), - Location(locus='region465', start=1618208, end=1619684, strand=1), - Location(locus='region466', start=1625354, end=1625422, strand=1), - Location(locus='region467', start=1630814, end=1630825, strand=1), - Location(locus='region468', start=1630827, end=1630837, strand=1), - Location(locus='region469', start=1630839, end=1630872, strand=1), - Location(locus='region470', start=1630874, end=1630875, strand=1), - Location(locus='region471', start=1630996, end=1631117, strand=1), - Location(locus='region472', start=1631391, end=1631908, strand=1), - Location(locus='region473', start=1631936, end=1631955, strand=1), - Location(locus='region474', start=1632057, end=1632128, strand=1), - Location(locus='region475', start=1632218, end=1632220, strand=1), - Location(locus='region476', start=1632231, end=1632289, strand=1), - Location(locus='region477', start=1632355, end=1632824, strand=1), - Location(locus='region478', start=1632856, end=1632858, strand=1), - Location(locus='region479', start=1633191, end=1634797, strand=1), - Location(locus='region480', start=1636003, end=1638399, strand=1), - Location(locus='region481', start=1644242, end=1644372, strand=1), - Location(locus='region482', start=1654154, end=1654206, strand=1), - Location(locus='region483', start=1655670, end=1655721, strand=1), - Location(locus='region484', start=1655814, end=1655815, strand=1), - Location(locus='region485', start=1656096, end=1656098, strand=1), - Location(locus='region486', start=1656099, end=1656208, strand=1), - Location(locus='region487', start=1656328, end=1656410, strand=1), - Location(locus='region488', start=1656516, end=1656596, strand=1), - Location(locus='region489', start=1672405, end=1672466, strand=1), - Location(locus='region490', start=1678950, end=1679019, strand=1), - Location(locus='region491', start=1685477, end=1685546, strand=1), - Location(locus='region492', start=1699863, end=1699920, strand=1), - Location(locus='region493', start=1702156, end=1702206, strand=1), - Location(locus='region494', start=1702384, end=1702470, strand=1), - Location(locus='region495', start=1702676, end=1702854, strand=1), - Location(locus='region496', start=1703071, end=1703128, strand=1), - Location(locus='region497', start=1710884, end=1710945, strand=1), - Location(locus='region498', start=1712842, end=1712892, strand=1), - Location(locus='region499', start=1713497, end=1713547, strand=1), - Location(locus='region500', start=1713673, end=1713753, strand=1), - Location(locus='region501', start=1722650, end=1722700, strand=1), - Location(locus='region502', start=1722809, end=1722890, strand=1), - Location(locus='region503', start=1723227, end=1723284, strand=1), - Location(locus='region504', start=1723515, end=1723595, strand=1), - Location(locus='region505', start=1725516, end=1725566, strand=1), - Location(locus='region506', start=1730045, end=1730095, strand=1), - Location(locus='region507', start=1730876, end=1730956, strand=1), - Location(locus='region508', start=1731135, end=1731203, strand=1), - Location(locus='region509', start=1735541, end=1735635, strand=1), - Location(locus='region510', start=1753012, end=1753062, strand=1), - Location(locus='region511', start=1753287, end=1753337, strand=1), - Location(locus='region512', start=1773952, end=1774109, strand=1), - Location(locus='region513', start=1779266, end=1789872, strand=1), - Location(locus='region514', start=1814850, end=1815130, strand=1), - Location(locus='region515', start=1828800, end=1828860, strand=1), - Location(locus='region516', start=1830066, end=1830125, strand=1), - Location(locus='region517', start=1863481, end=1863575, strand=1), - Location(locus='region518', start=1863723, end=1863733, strand=1), - Location(locus='region519', start=1864008, end=1864112, strand=1), - Location(locus='region520', start=1864256, end=1864323, strand=1), - Location(locus='region521', start=1864394, end=1864468, strand=1), - Location(locus='region522', start=1864554, end=1864567, strand=1), - Location(locus='region523', start=1864568, end=1864580, strand=1), - Location(locus='region524', start=1864702, end=1864872, strand=1), - Location(locus='region525', start=1864885, end=1864924, strand=1), - Location(locus='region526', start=1865012, end=1865070, strand=1), - Location(locus='region527', start=1875415, end=1875504, strand=1), - Location(locus='region528', start=1875877, end=1875967, strand=1), - Location(locus='region529', start=1876150, end=1876234, strand=1), - Location(locus='region530', start=1876404, end=1876592, strand=1), - Location(locus='region531', start=1876600, end=1876674, strand=1), - Location(locus='region532', start=1879287, end=1879381, strand=1), - Location(locus='region533', start=1879425, end=1879426, strand=1), - Location(locus='region534', start=1879494, end=1879503, strand=1), - Location(locus='region535', start=1879504, end=1879619, strand=1), - Location(locus='region536', start=1879631, end=1879638, strand=1), - Location(locus='region537', start=1879650, end=1879659, strand=1), - Location(locus='region538', start=1880680, end=1880748, strand=1), - Location(locus='region539', start=1880756, end=1880809, strand=1), - Location(locus='region540', start=1880823, end=1880877, strand=1), - Location(locus='region541', start=1880884, end=1880943, strand=1), - Location(locus='region542', start=1881812, end=1881901, strand=1), - Location(locus='region543', start=1882244, end=1882358, strand=1), - Location(locus='region544', start=1882541, end=1882625, strand=1), - Location(locus='region545', start=1882694, end=1882760, strand=1), - Location(locus='region546', start=1882792, end=1882979, strand=1), - Location(locus='region547', start=1882988, end=1883062, strand=1), - Location(locus='region548', start=1883354, end=1883404, strand=1), - Location(locus='region549', start=1885850, end=1885902, strand=1), - Location(locus='region550', start=1886335, end=1886387, strand=1), - Location(locus='region551', start=1886690, end=1886751, strand=1), - Location(locus='region552', start=1886989, end=1887057, strand=1), - Location(locus='region553', start=1887065, end=1887118, strand=1), - Location(locus='region554', start=1887132, end=1887186, strand=1), - Location(locus='region555', start=1887193, end=1887252, strand=1), - Location(locus='region556', start=1889505, end=1889555, strand=1), - Location(locus='region557', start=1895347, end=1895599, strand=1), - Location(locus='region558', start=1907452, end=1907583, strand=1), - Location(locus='region559', start=1914970, end=1914986, strand=1), - Location(locus='region560', start=1914987, end=1914995, strand=1), - Location(locus='region561', start=1914998, end=1914999, strand=1), - Location(locus='region562', start=1933297, end=1933384, strand=1), - Location(locus='region563', start=1933712, end=1933762, strand=1), - Location(locus='region564', start=1946846, end=1947027, strand=1), - Location(locus='region565', start=1955433, end=1955483, strand=1), - Location(locus='region566', start=1955581, end=1955615, strand=1), - Location(locus='region567', start=1955638, end=1955672, strand=1), - Location(locus='region568', start=1963153, end=1963221, strand=1), - Location(locus='region569', start=1963420, end=1963705, strand=1), - Location(locus='region570', start=1963888, end=1963956, strand=1), - Location(locus='region571', start=1967880, end=1967931, strand=1), - Location(locus='region572', start=1971233, end=1971334, strand=1), - Location(locus='region573', start=1981613, end=1984775, strand=1), - Location(locus='region574', start=1987173, end=1987241, strand=1), - Location(locus='region575', start=1987344, end=1987406, strand=1), - Location(locus='region576', start=1987693, end=1989068, strand=1), - Location(locus='region577', start=1989894, end=1989972, strand=1), - Location(locus='region578', start=1989982, end=1990093, strand=1), - Location(locus='region579', start=1990109, end=1990114, strand=1), - Location(locus='region580', start=1990322, end=1990823, strand=1), - Location(locus='region581', start=1991181, end=1991480, strand=1), - Location(locus='region582', start=1991569, end=1992029, strand=1), - Location(locus='region583', start=1992054, end=1992111, strand=1), - Location(locus='region584', start=1992282, end=1992334, strand=1), - Location(locus='region585', start=1996092, end=1998618, strand=1), - Location(locus='region586', start=2000924, end=2000998, strand=1), - Location(locus='region587', start=2001009, end=2001062, strand=1), - Location(locus='region588', start=2001205, end=2001716, strand=1), - Location(locus='region589', start=2002029, end=2002036, strand=1), - Location(locus='region590', start=2002125, end=2002328, strand=1), - Location(locus='region591', start=2002405, end=2002406, strand=1), - Location(locus='region592', start=2025296, end=2025858, strand=1), - Location(locus='region593', start=2025891, end=2026167, strand=1), - Location(locus='region594', start=2028420, end=2029246, strand=1), - Location(locus='region595', start=2030328, end=2030648, strand=1), - Location(locus='region596', start=2030703, end=2030986, strand=1), - Location(locus='region597', start=2039731, end=2039781, strand=1), - Location(locus='region598', start=2043797, end=2043858, strand=1), - Location(locus='region599', start=2045048, end=2045107, strand=1), - Location(locus='region600', start=2045963, end=2045964, strand=1), - Location(locus='region601', start=2045969, end=2045970, strand=1), - Location(locus='region602', start=2046100, end=2046195, strand=1), - Location(locus='region603', start=2047627, end=2047721, strand=1), - Location(locus='region604', start=2048789, end=2048842, strand=1), - Location(locus='region605', start=2050287, end=2050398, strand=1), - Location(locus='region606', start=2059425, end=2059608, strand=1), - Location(locus='region607', start=2061412, end=2061430, strand=1), - Location(locus='region608', start=2061431, end=2062159, strand=1), - Location(locus='region609', start=2062286, end=2062369, strand=1), - Location(locus='region610', start=2062448, end=2062515, strand=1), - Location(locus='region611', start=2069016, end=2069069, strand=1), - Location(locus='region612', start=2074430, end=2074840, strand=1), - Location(locus='region613', start=2088461, end=2088499, strand=1), - Location(locus='region614', start=2088773, end=2088933, strand=1), - Location(locus='region615', start=2088946, end=2088949, strand=1), - Location(locus='region616', start=2089092, end=2089162, strand=1), - Location(locus='region617', start=2089292, end=2089348, strand=1), - Location(locus='region618', start=2096825, end=2096840, strand=1), - Location(locus='region619', start=2096843, end=2096849, strand=1), - Location(locus='region620', start=2102846, end=2102899, strand=1), - Location(locus='region621', start=2115708, end=2115758, strand=1), - Location(locus='region622', start=2133474, end=2133475, strand=1), - Location(locus='region623', start=2133993, end=2134046, strand=1), - Location(locus='region624', start=2134922, end=2134975, strand=1), - Location(locus='region625', start=2135424, end=2135493, strand=1), - Location(locus='region626', start=2135533, end=2135616, strand=1), - Location(locus='region627', start=2135665, end=2135748, strand=1), - Location(locus='region628', start=2146058, end=2146132, strand=1), - Location(locus='region629', start=2156798, end=2156878, strand=1), - Location(locus='region630', start=2157477, end=2157557, strand=1), - Location(locus='region631', start=2162931, end=2167311, strand=1), - Location(locus='region632', start=2167846, end=2167901, strand=1), - Location(locus='region633', start=2168808, end=2168872, strand=1), - Location(locus='region634', start=2168886, end=2168950, strand=1), - Location(locus='region635', start=2168982, end=2169056, strand=1), - Location(locus='region636', start=2169060, end=2169134, strand=1), - Location(locus='region637', start=2169571, end=2169628, strand=1), - Location(locus='region638', start=2170281, end=2170334, strand=1), - Location(locus='region639', start=2181376, end=2181412, strand=1), - Location(locus='region640', start=2193009, end=2193021, strand=1), - Location(locus='region641', start=2195906, end=2196780, strand=1), - Location(locus='region642', start=2196856, end=2197248, strand=1), - Location(locus='region643', start=2197279, end=2197365, strand=1), - Location(locus='region644', start=2198685, end=2198819, strand=1), - Location(locus='region645', start=2230720, end=2230773, strand=1), - Location(locus='region646', start=2244992, end=2245020, strand=1), - Location(locus='region647', start=2260253, end=2260309, strand=1), - Location(locus='region648', start=2260343, end=2260439, strand=1), - Location(locus='region649', start=2261440, end=2261518, strand=1), - Location(locus='region650', start=2262004, end=2263175, strand=1), - Location(locus='region651', start=2266486, end=2266487, strand=1), - Location(locus='region652', start=2266507, end=2266508, strand=1), - Location(locus='region653', start=2266516, end=2266517, strand=1), - Location(locus='region654', start=2266549, end=2266550, strand=1), - Location(locus='region655', start=2266552, end=2266553, strand=1), - Location(locus='region656', start=2266582, end=2266583, strand=1), - Location(locus='region657', start=2266597, end=2266598, strand=1), - Location(locus='region658', start=2266603, end=2266604, strand=1), - Location(locus='region659', start=2266623, end=2266624, strand=1), - Location(locus='region660', start=2268721, end=2268725, strand=1), - Location(locus='region661', start=2294815, end=2294911, strand=1), - Location(locus='region662', start=2295174, end=2295242, strand=1), - Location(locus='region663', start=2295289, end=2296015, strand=1), - Location(locus='region664', start=2296029, end=2296427, strand=1), - Location(locus='region665', start=2296959, end=2297045, strand=1), - Location(locus='region666', start=2298089, end=2298160, strand=1), - Location(locus='region667', start=2299186, end=2300128, strand=1), - Location(locus='region668', start=2300207, end=2300388, strand=1), - Location(locus='region669', start=2300446, end=2300580, strand=1), - Location(locus='region670', start=2300911, end=2301007, strand=1), - Location(locus='region671', start=2301264, end=2301332, strand=1), - Location(locus='region672', start=2301379, end=2302105, strand=1), - Location(locus='region673', start=2302112, end=2302517, strand=1), - Location(locus='region674', start=2303046, end=2303132, strand=1), - Location(locus='region675', start=2304131, end=2304202, strand=1), - Location(locus='region676', start=2305255, end=2306197, strand=1), - Location(locus='region677', start=2306276, end=2306457, strand=1), - Location(locus='region678', start=2306512, end=2306646, strand=1), - Location(locus='region679', start=2317128, end=2317129, strand=1), - Location(locus='region680', start=2317135, end=2317136, strand=1), - Location(locus='region681', start=2329858, end=2330072, strand=1), - Location(locus='region682', start=2330143, end=2330214, strand=1), - Location(locus='region683', start=2337968, end=2338102, strand=1), - Location(locus='region684', start=2338206, end=2338215, strand=1), - Location(locus='region685', start=2338216, end=2338217, strand=1), - Location(locus='region686', start=2338415, end=2338416, strand=1), - Location(locus='region687', start=2338421, end=2338422, strand=1), - Location(locus='region688', start=2338424, end=2338425, strand=1), - Location(locus='region689', start=2338427, end=2338428, strand=1), - Location(locus='region690', start=2338430, end=2338431, strand=1), - Location(locus='region691', start=2338433, end=2338434, strand=1), - Location(locus='region692', start=2338456, end=2338457, strand=1), - Location(locus='region693', start=2338676, end=2338677, strand=1), - Location(locus='region694', start=2338678, end=2338679, strand=1), - Location(locus='region695', start=2338691, end=2338692, strand=1), - Location(locus='region696', start=2338700, end=2338702, strand=1), - Location(locus='region697', start=2338703, end=2338704, strand=1), - Location(locus='region698', start=2338706, end=2338707, strand=1), - Location(locus='region699', start=2338715, end=2338716, strand=1), - Location(locus='region700', start=2338719, end=2338720, strand=1), - Location(locus='region701', start=2339363, end=2339432, strand=1), - Location(locus='region702', start=2339441, end=2339510, strand=1), - Location(locus='region703', start=2339512, end=2339573, strand=1), - Location(locus='region704', start=2339888, end=2340051, strand=1), - Location(locus='region705', start=2340561, end=2340695, strand=1), - Location(locus='region706', start=2341429, end=2341479, strand=1), - Location(locus='region707', start=2347386, end=2347620, strand=1), - Location(locus='region708', start=2356873, end=2356918, strand=1), - Location(locus='region709', start=2356927, end=2356933, strand=1), - Location(locus='region710', start=2357181, end=2357185, strand=1), - Location(locus='region711', start=2357249, end=2357268, strand=1), - Location(locus='region712', start=2357291, end=2357297, strand=1), - Location(locus='region713', start=2357314, end=2357321, strand=1), - Location(locus='region714', start=2357417, end=2357420, strand=1), - Location(locus='region715', start=2357426, end=2357607, strand=1), - Location(locus='region716', start=2357841, end=2357901, strand=1), - Location(locus='region717', start=2358659, end=2358715, strand=1), - Location(locus='region718', start=2358755, end=2358832, strand=1), - Location(locus='region719', start=2358918, end=2358991, strand=1), - Location(locus='region720', start=2358995, end=2359057, strand=1), - Location(locus='region721', start=2359163, end=2359213, strand=1), - Location(locus='region722', start=2359554, end=2359613, strand=1), - Location(locus='region723', start=2359778, end=2359852, strand=1), - Location(locus='region724', start=2359923, end=2359982, strand=1), - Location(locus='region725', start=2360650, end=2360660, strand=1), - Location(locus='region726', start=2360730, end=2360740, strand=1), - Location(locus='region727', start=2361908, end=2361909, strand=1), - Location(locus='region728', start=2363680, end=2363682, strand=1), - Location(locus='region729', start=2365407, end=2366778, strand=1), - Location(locus='region730', start=2366889, end=2366967, strand=1), - Location(locus='region731', start=2367028, end=2367060, strand=1), - Location(locus='region732', start=2372430, end=2372565, strand=1), - Location(locus='region733', start=2380217, end=2380261, strand=1), - Location(locus='region734', start=2381446, end=2381513, strand=1), - Location(locus='region735', start=2387281, end=2387659, strand=1), - Location(locus='region736', start=2401813, end=2401936, strand=1), - Location(locus='region737', start=2423328, end=2423387, strand=1), - Location(locus='region738', start=2423424, end=2423425, strand=1), - Location(locus='region739', start=2423526, end=2423687, strand=1), - Location(locus='region740', start=2423705, end=2423775, strand=1), - Location(locus='region741', start=2423789, end=2424293, strand=1), - Location(locus='region742', start=2424483, end=2424537, strand=1), - Location(locus='region743', start=2430107, end=2431481, strand=1), - Location(locus='region744', start=2439177, end=2439954, strand=1), - Location(locus='region745', start=2440279, end=2440334, strand=1), - Location(locus='region746', start=2449219, end=2449221, strand=1), - Location(locus='region747', start=2458391, end=2458471, strand=1), - Location(locus='region748', start=2461322, end=2461510, strand=1), - Location(locus='region749', start=2462528, end=2462594, strand=1), - Location(locus='region750', start=2466995, end=2467029, strand=1), - Location(locus='region751', start=2470043, end=2470086, strand=1), - Location(locus='region752', start=2482061, end=2482111, strand=1), - Location(locus='region753', start=2482418, end=2482468, strand=1), - Location(locus='region754', start=2522186, end=2522192, strand=1), - Location(locus='region755', start=2522194, end=2522219, strand=1), - Location(locus='region756', start=2523182, end=2523239, strand=1), - Location(locus='region757', start=2531886, end=2532244, strand=1), - Location(locus='region758', start=2546432, end=2546497, strand=1), - Location(locus='region759', start=2550002, end=2551378, strand=1), - Location(locus='region760', start=2554864, end=2554933, strand=1), - Location(locus='region761', start=2577285, end=2577362, strand=1), - Location(locus='region762', start=2577679, end=2577732, strand=1), - Location(locus='region763', start=2617342, end=2617407, strand=1), - Location(locus='region764', start=2625882, end=2626688, strand=1), - Location(locus='region765', start=2627503, end=2627556, strand=1), - Location(locus='region766', start=2629274, end=2629354, strand=1), - Location(locus='region767', start=2629593, end=2629672, strand=1), - Location(locus='region768', start=2630144, end=2630239, strand=1), - Location(locus='region769', start=2630868, end=2630926, strand=1), - Location(locus='region770', start=2631042, end=2631119, strand=1), - Location(locus='region771', start=2631358, end=2631437, strand=1), - Location(locus='region772', start=2631598, end=2631599, strand=1), - Location(locus='region773', start=2631619, end=2631620, strand=1), - Location(locus='region774', start=2631900, end=2631995, strand=1), - Location(locus='region775', start=2632922, end=2637037, strand=1), - Location(locus='region776', start=2637255, end=2637534, strand=1), - Location(locus='region777', start=2638349, end=2638560, strand=1), - Location(locus='region778', start=2638985, end=2639622, strand=1), - Location(locus='region779', start=2651435, end=2651440, strand=1), - Location(locus='region780', start=2651445, end=2651447, strand=1), - Location(locus='region781', start=2651843, end=2651910, strand=1), - Location(locus='region782', start=2683501, end=2683554, strand=1), - Location(locus='region783', start=2687129, end=2687257, strand=1), - Location(locus='region784', start=2693239, end=2693589, strand=1), - Location(locus='region785', start=2693609, end=2693854, strand=1), - Location(locus='region786', start=2700466, end=2700531, strand=1), - Location(locus='region787', start=2703891, end=2704019, strand=1), - Location(locus='region788', start=2704885, end=2704886, strand=1), - Location(locus='region789', start=2716308, end=2716392, strand=1), - Location(locus='region790', start=2720671, end=2721448, strand=1), - Location(locus='region791', start=2721812, end=2721867, strand=1), - Location(locus='region792', start=2724201, end=2724221, strand=1), - Location(locus='region793', start=2729618, end=2729620, strand=1), - Location(locus='region794', start=2729832, end=2729834, strand=1), - Location(locus='region795', start=2740574, end=2740601, strand=1), - Location(locus='region796', start=2751596, end=2751658, strand=1), - Location(locus='region797', start=2784601, end=2785982, strand=1), - Location(locus='region798', start=2795376, end=2795395, strand=1), - Location(locus='region799', start=2795561, end=2795578, strand=1), - Location(locus='region800', start=2795674, end=2795724, strand=1), - Location(locus='region801', start=2795854, end=2795868, strand=1), - Location(locus='region802', start=2795872, end=2796011, strand=1), - Location(locus='region803', start=2796483, end=2796488, strand=1), - Location(locus='region804', start=2796490, end=2796492, strand=1), - Location(locus='region805', start=2796747, end=2796761, strand=1), - Location(locus='region806', start=2796871, end=2796923, strand=1), - Location(locus='region807', start=2797259, end=2797355, strand=1), - Location(locus='region808', start=2801405, end=2801452, strand=1), - Location(locus='region809', start=2801456, end=2801471, strand=1), - Location(locus='region810', start=2801822, end=2802329, strand=1), - Location(locus='region811', start=2802330, end=2802331, strand=1), - Location(locus='region812', start=2802743, end=2802850, strand=1), - Location(locus='region813', start=2802853, end=2803162, strand=1), - Location(locus='region814', start=2803467, end=2803712, strand=1), - Location(locus='region815', start=2803721, end=2803725, strand=1), - Location(locus='region816', start=2803726, end=2803773, strand=1), - Location(locus='region817', start=2803777, end=2803783, strand=1), - Location(locus='region818', start=2803823, end=2803883, strand=1), - Location(locus='region819', start=2804102, end=2804164, strand=1), - Location(locus='region820', start=2804375, end=2804706, strand=1), - Location(locus='region821', start=2804720, end=2804723, strand=1), - Location(locus='region822', start=2804746, end=2804750, strand=1), - Location(locus='region823', start=2804756, end=2804823, strand=1), - Location(locus='region824', start=2804906, end=2805754, strand=1), - Location(locus='region825', start=2806110, end=2806206, strand=1), - Location(locus='region826', start=2822573, end=2822586, strand=1), - Location(locus='region827', start=2822617, end=2822669, strand=1), - Location(locus='region828', start=2828486, end=2829938, strand=1), - Location(locus='region829', start=2836272, end=2836324, strand=1), - Location(locus='region830', start=2850917, end=2850999, strand=1), - Location(locus='region831', start=2866465, end=2866759, strand=1), - Location(locus='region832', start=2866851, end=2867786, strand=1), - Location(locus='region833', start=2877243, end=2877305, strand=1), - Location(locus='region834', start=2878035, end=2878097, strand=1), - Location(locus='region835', start=2880155, end=2880261, strand=1), - Location(locus='region836', start=2883832, end=2883904, strand=1), - Location(locus='region837', start=2884038, end=2884153, strand=1), - Location(locus='region838', start=2887448, end=2887449, strand=1), - Location(locus='region839', start=2921969, end=2922026, strand=1), - Location(locus='region840', start=2922097, end=2922119, strand=1), - Location(locus='region841', start=2922181, end=2922254, strand=1), - Location(locus='region842', start=2922357, end=2922373, strand=1), - Location(locus='region843', start=2922436, end=2922459, strand=1), - Location(locus='region844', start=2922725, end=2922835, strand=1), - Location(locus='region845', start=2922867, end=2922930, strand=1), - Location(locus='region846', start=2922937, end=2922960, strand=1), - Location(locus='region847', start=2923091, end=2923143, strand=1), - Location(locus='region848', start=2935119, end=2935172, strand=1), - Location(locus='region849', start=2943754, end=2943801, strand=1), - Location(locus='region850', start=2944205, end=2945233, strand=1), - Location(locus='region851', start=2953436, end=2953513, strand=1), - Location(locus='region852', start=2960226, end=2960592, strand=1), - Location(locus='region853', start=2960877, end=2960880, strand=1), - Location(locus='region854', start=2960929, end=2961063, strand=1), - Location(locus='region855', start=2961069, end=2961071, strand=1), - Location(locus='region856', start=2961078, end=2961083, strand=1), - Location(locus='region857', start=2961085, end=2961231, strand=1), - Location(locus='region858', start=2961334, end=2961341, strand=1), - Location(locus='region859', start=2961355, end=2961356, strand=1), - Location(locus='region860', start=2961366, end=2961401, strand=1), - Location(locus='region861', start=2961409, end=2961412, strand=1), - Location(locus='region862', start=2961446, end=2961938, strand=1), - Location(locus='region863', start=2961961, end=2961962, strand=1), - Location(locus='region864', start=2971755, end=2971868, strand=1), - Location(locus='region865', start=2971940, end=2971990, strand=1), - Location(locus='region866', start=2972101, end=2973473, strand=1), - Location(locus='region867', start=2974050, end=2974162, strand=1), - Location(locus='region868', start=2974273, end=2974345, strand=1), - Location(locus='region869', start=2974410, end=2974651, strand=1), - Location(locus='region870', start=2974652, end=2974758, strand=1), - Location(locus='region871', start=2974767, end=2974912, strand=1), - Location(locus='region872', start=2974913, end=2975136, strand=1), - Location(locus='region873', start=2975263, end=2975329, strand=1), - Location(locus='region874', start=2975390, end=2975461, strand=1), - Location(locus='region875', start=2975465, end=2975697, strand=1), - Location(locus='region876', start=2975726, end=2975962, strand=1), - Location(locus='region877', start=2978905, end=2979050, strand=1), - Location(locus='region878', start=2980970, end=2980998, strand=1), - Location(locus='region879', start=2982937, end=2983859, strand=1), - Location(locus='region880', start=2989950, end=2989952, strand=1), - Location(locus='region881', start=2990578, end=2990706, strand=1), - Location(locus='region882', start=2996000, end=2996173, strand=1), - Location(locus='region883', start=3000927, end=3000997, strand=1), - Location(locus='region884', start=3001076, end=3001136, strand=1), - Location(locus='region885', start=3001304, end=3001385, strand=1), - Location(locus='region886', start=3001421, end=3001480, strand=1), - Location(locus='region887', start=3001760, end=3001811, strand=1), - Location(locus='region888', start=3002296, end=3002366, strand=1), - Location(locus='region889', start=3002445, end=3002505, strand=1), - Location(locus='region890', start=3002673, end=3002754, strand=1), - Location(locus='region891', start=3002790, end=3002849, strand=1), - Location(locus='region892', start=3003129, end=3003180, strand=1), - Location(locus='region893', start=3007032, end=3007227, strand=1), - Location(locus='region894', start=3018717, end=3018767, strand=1), - Location(locus='region895', start=3018795, end=3018854, strand=1), - Location(locus='region896', start=3022728, end=3022778, strand=1), - Location(locus='region897', start=3022806, end=3022865, strand=1), - Location(locus='region898', start=3026262, end=3026284, strand=1), - Location(locus='region899', start=3054576, end=3054577, strand=1), - Location(locus='region900', start=3054578, end=3054941, strand=1), - Location(locus='region901', start=3054952, end=3055236, strand=1), - Location(locus='region902', start=3059792, end=3059850, strand=1), - Location(locus='region903', start=3073062, end=3073136, strand=1), - Location(locus='region904', start=3076898, end=3076962, strand=1), - Location(locus='region905', start=3078168, end=3078218, strand=1), - Location(locus='region906', start=3082462, end=3082661, strand=1), - Location(locus='region907', start=3082704, end=3082763, strand=1), - Location(locus='region908', start=3097654, end=3097715, strand=1), - Location(locus='region909', start=3100170, end=3100401, strand=1), - Location(locus='region910', start=3100446, end=3100511, strand=1), - Location(locus='region911', start=3100515, end=3100571, strand=1), - Location(locus='region912', start=3100694, end=3100799, strand=1), - Location(locus='region913', start=3100879, end=3100939, strand=1), - Location(locus='region914', start=3100965, end=3101132, strand=1), - Location(locus='region915', start=3101235, end=3101377, strand=1), - Location(locus='region916', start=3101429, end=3101543, strand=1), - Location(locus='region917', start=3101660, end=3101731, strand=1), - Location(locus='region918', start=3101861, end=3101911, strand=1), - Location(locus='region919', start=3102099, end=3102229, strand=1), - Location(locus='region920', start=3102340, end=3102390, strand=1), - Location(locus='region921', start=3104976, end=3105044, strand=1), - Location(locus='region922', start=3112312, end=3112313, strand=1), - Location(locus='region923', start=3112459, end=3112460, strand=1), - Location(locus='region924', start=3113017, end=3113104, strand=1), - Location(locus='region925', start=3113775, end=3113862, strand=1), - Location(locus='region926', start=3116414, end=3116522, strand=1), - Location(locus='region927', start=3116682, end=3116766, strand=1), - Location(locus='region928', start=3116843, end=3116989, strand=1), - Location(locus='region929', start=3119560, end=3119563, strand=1), - Location(locus='region930', start=3119566, end=3122702, strand=1), - Location(locus='region931', start=3122803, end=3122918, strand=1), - Location(locus='region932', start=3122931, end=3122942, strand=1), - Location(locus='region933', start=3122948, end=3122954, strand=1), - Location(locus='region934', start=3123027, end=3123283, strand=1), - Location(locus='region935', start=3123316, end=3123353, strand=1), - Location(locus='region936', start=3123422, end=3123424, strand=1), - Location(locus='region937', start=3132887, end=3133461, strand=1), - Location(locus='region938', start=3135783, end=3136357, strand=1), - Location(locus='region939', start=3138022, end=3138085, strand=1), - Location(locus='region940', start=3147107, end=3147108, strand=1), - Location(locus='region941', start=3147110, end=3147119, strand=1), - Location(locus='region942', start=3155875, end=3156094, strand=1), - Location(locus='region943', start=3160526, end=3160587, strand=1), - Location(locus='region944', start=3162643, end=3162703, strand=1), - Location(locus='region945', start=3162806, end=3162923, strand=1), - Location(locus='region946', start=3163470, end=3163548, strand=1), - Location(locus='region947', start=3163615, end=3163617, strand=1), - Location(locus='region948', start=3163619, end=3164033, strand=1), - Location(locus='region949', start=3171459, end=3171634, strand=1), - Location(locus='region950', start=3189479, end=3189617, strand=1), - Location(locus='region951', start=3192190, end=3192363, strand=1), - Location(locus='region952', start=3194136, end=3194535, strand=1), - Location(locus='region953', start=3194658, end=3194763, strand=1), - Location(locus='region954', start=3194791, end=3194794, strand=1), - Location(locus='region955', start=3194935, end=3195045, strand=1), - Location(locus='region956', start=3195058, end=3195120, strand=1), - Location(locus='region957', start=3195203, end=3195283, strand=1), - Location(locus='region958', start=3196071, end=3196122, strand=1), - Location(locus='region959', start=3201556, end=3201655, strand=1), - Location(locus='region960', start=3226325, end=3226402, strand=1), - Location(locus='region961', start=3232506, end=3232871, strand=1), - Location(locus='region962', start=3239466, end=3239794, strand=1), - Location(locus='region963', start=3245098, end=3245166, strand=1), - Location(locus='region964', start=3245321, end=3245389, strand=1), - Location(locus='region965', start=3247233, end=3247304, strand=1), - Location(locus='region966', start=3247313, end=3247471, strand=1), - Location(locus='region967', start=3247557, end=3247739, strand=1), - Location(locus='region968', start=3247809, end=3248173, strand=1), - Location(locus='region969', start=3248283, end=3248335, strand=1), - Location(locus='region970', start=3251411, end=3251470, strand=1), - Location(locus='region971', start=3252647, end=3252718, strand=1), - Location(locus='region972', start=3252727, end=3252885, strand=1), - Location(locus='region973', start=3252971, end=3253153, strand=1), - Location(locus='region974', start=3253223, end=3253587, strand=1), - Location(locus='region975', start=3253733, end=3253738, strand=1), - Location(locus='region976', start=3257962, end=3258024, strand=1), - Location(locus='region977', start=3258181, end=3258232, strand=1), - Location(locus='region978', start=3258342, end=3258404, strand=1), - Location(locus='region979', start=3262593, end=3262652, strand=1), - Location(locus='region980', start=3266035, end=3266081, strand=1), - Location(locus='region981', start=3276956, end=3277006, strand=1), - Location(locus='region982', start=3277821, end=3277904, strand=1), - Location(locus='region983', start=3281070, end=3281123, strand=1), - Location(locus='region984', start=3281221, end=3281240, strand=1), - Location(locus='region985', start=3284730, end=3284810, strand=1), - Location(locus='region986', start=3287950, end=3288005, strand=1), - Location(locus='region987', start=3290432, end=3290482, strand=1), - Location(locus='region988', start=3291393, end=3291510, strand=1), - Location(locus='region989', start=3292983, end=3293052, strand=1), - Location(locus='region990', start=3293178, end=3293237, strand=1), - Location(locus='region991', start=3295507, end=3295562, strand=1), - Location(locus='region992', start=3296594, end=3296665, strand=1), - Location(locus='region993', start=3297173, end=3297238, strand=1), - Location(locus='region994', start=3307727, end=3307761, strand=1), - Location(locus='region995', start=3311027, end=3311090, strand=1), - Location(locus='region996', start=3311308, end=3311393, strand=1), - Location(locus='region997', start=3311534, end=3311599, strand=1), - Location(locus='region998', start=3313346, end=3313396, strand=1), - Location(locus='region999', start=3314116, end=3314179, strand=1), - Location(locus='region1000', start=3314397, end=3314482, strand=1), - Location(locus='region1001', start=3314623, end=3314688, strand=1), - Location(locus='region1002', start=3317572, end=3317743, strand=1), - Location(locus='region1003', start=3319468, end=3319665, strand=1), - Location(locus='region1004', start=3333753, end=3333984, strand=1), - Location(locus='region1005', start=3333990, end=3334184, strand=1), - Location(locus='region1006', start=3334239, end=3334370, strand=1), - Location(locus='region1007', start=3334557, end=3334609, strand=1), - Location(locus='region1008', start=3334646, end=3334739, strand=1), - Location(locus='region1009', start=3334822, end=3334960, strand=1), - Location(locus='region1010', start=3335016, end=3335084, strand=1), - Location(locus='region1011', start=3335246, end=3335317, strand=1), - Location(locus='region1012', start=3335357, end=3335410, strand=1), - Location(locus='region1013', start=3335447, end=3335497, strand=1), - Location(locus='region1014', start=3335504, end=3335566, strand=1), - Location(locus='region1015', start=3335741, end=3335815, strand=1), - Location(locus='region1016', start=3336500, end=3336803, strand=1), - Location(locus='region1017', start=3343348, end=3343447, strand=1), - Location(locus='region1018', start=3348477, end=3348544, strand=1), - Location(locus='region1019', start=3351084, end=3351220, strand=1), - Location(locus='region1020', start=3369930, end=3369931, strand=1), - Location(locus='region1021', start=3369937, end=3369942, strand=1), - Location(locus='region1022', start=3376515, end=3376543, strand=1), - Location(locus='region1023', start=3376746, end=3376809, strand=1), - Location(locus='region1024', start=3376921, end=3377368, strand=1), - Location(locus='region1025', start=3377645, end=3378276, strand=1), - Location(locus='region1026', start=3378329, end=3378443, strand=1), - Location(locus='region1027', start=3378895, end=3378960, strand=1), - Location(locus='region1028', start=3379196, end=3379285, strand=1), - Location(locus='region1029', start=3379358, end=3380715, strand=1), - Location(locus='region1030', start=3380907, end=3381021, strand=1), - Location(locus='region1031', start=3381307, end=3382755, strand=1), - Location(locus='region1032', start=3415197, end=3415211, strand=1), - Location(locus='region1033', start=3430332, end=3430388, strand=1), - Location(locus='region1034', start=3451379, end=3451439, strand=1), - Location(locus='region1035', start=3463548, end=3463559, strand=1), - Location(locus='region1036', start=3477289, end=3477404, strand=1), - Location(locus='region1037', start=3481318, end=3482769, strand=1), - Location(locus='region1038', start=3483942, end=3485117, strand=1), - Location(locus='region1039', start=3491173, end=3491238, strand=1), - Location(locus='region1040', start=3491292, end=3491383, strand=1), - Location(locus='region1041', start=3491605, end=3491662, strand=1), - Location(locus='region1042', start=3491745, end=3491860, strand=1), - Location(locus='region1043', start=3501334, end=3501335, strand=1), - Location(locus='region1044', start=3502155, end=3502265, strand=1), - Location(locus='region1045', start=3524464, end=3524527, strand=1), - Location(locus='region1046', start=3528083, end=3528084, strand=1), - Location(locus='region1047', start=3528086, end=3528087, strand=1), - Location(locus='region1048', start=3528098, end=3528099, strand=1), - Location(locus='region1049', start=3528101, end=3528102, strand=1), - Location(locus='region1050', start=3528116, end=3528117, strand=1), - Location(locus='region1051', start=3528118, end=3528120, strand=1), - Location(locus='region1052', start=3528128, end=3528129, strand=1), - Location(locus='region1053', start=3528139, end=3528140, strand=1), - Location(locus='region1054', start=3528143, end=3528144, strand=1), - Location(locus='region1055', start=3528157, end=3528159, strand=1), - Location(locus='region1056', start=3528164, end=3528165, strand=1), - Location(locus='region1057', start=3528191, end=3528192, strand=1), - Location(locus='region1058', start=3528197, end=3528198, strand=1), - Location(locus='region1059', start=3528674, end=3529181, strand=1), - Location(locus='region1060', start=3537803, end=3537820, strand=1), - Location(locus='region1061', start=3551223, end=3554075, strand=1), - Location(locus='region1062', start=3558759, end=3558794, strand=1), - Location(locus='region1063', start=3572554, end=3572610, strand=1), - Location(locus='region1064', start=3590630, end=3590687, strand=1), - Location(locus='region1065', start=3594262, end=3594465, strand=1), - Location(locus='region1066', start=3595987, end=3596005, strand=1), - Location(locus='region1067', start=3598349, end=3598405, strand=1), - Location(locus='region1068', start=3598436, end=3598532, strand=1), - Location(locus='region1069', start=3598641, end=3598719, strand=1), - Location(locus='region1070', start=3617102, end=3617103, strand=1), - Location(locus='region1071', start=3626606, end=3626667, strand=1), - Location(locus='region1072', start=3628084, end=3628147, strand=1), - Location(locus='region1073', start=3658635, end=3658712, strand=1), - Location(locus='region1074', start=3663723, end=3664000, strand=1), - Location(locus='region1075', start=3690944, end=3691077, strand=1), - Location(locus='region1076', start=3704903, end=3704991, strand=1), - Location(locus='region1077', start=3707577, end=3707634, strand=1), - Location(locus='region1078', start=3710374, end=3712827, strand=1), - Location(locus='region1079', start=3724548, end=3724618, strand=1), - Location(locus='region1080', start=3729448, end=3729597, strand=1), - Location(locus='region1081', start=3729626, end=3729676, strand=1), - Location(locus='region1082', start=3730345, end=3732799, strand=1), - Location(locus='region1083', start=3734471, end=3734529, strand=1), - Location(locus='region1084', start=3735634, end=3736288, strand=1), - Location(locus='region1085', start=3736501, end=3736555, strand=1), - Location(locus='region1086', start=3736693, end=3736747, strand=1), - Location(locus='region1087', start=3737092, end=3737207, strand=1), - Location(locus='region1088', start=3737268, end=3737497, strand=1), - Location(locus='region1089', start=3737804, end=3737808, strand=1), - Location(locus='region1090', start=3737814, end=3737818, strand=1), - Location(locus='region1091', start=3737828, end=3737836, strand=1), - Location(locus='region1092', start=3737992, end=3738961, strand=1), - Location(locus='region1093', start=3738977, end=3738985, strand=1), - Location(locus='region1094', start=3739052, end=3739056, strand=1), - Location(locus='region1095', start=3739131, end=3739133, strand=1), - Location(locus='region1096', start=3739159, end=3739163, strand=1), - Location(locus='region1097', start=3739194, end=3739202, strand=1), - Location(locus='region1098', start=3739207, end=3739899, strand=1), - Location(locus='region1099', start=3739960, end=3740010, strand=1), - Location(locus='region1100', start=3740065, end=3740131, strand=1), - Location(locus='region1101', start=3740138, end=3740140, strand=1), - Location(locus='region1102', start=3740161, end=3740208, strand=1), - Location(locus='region1103', start=3740214, end=3740229, strand=1), - Location(locus='region1104', start=3740302, end=3740322, strand=1), - Location(locus='region1105', start=3740338, end=3740574, strand=1), - Location(locus='region1106', start=3740592, end=3740604, strand=1), - Location(locus='region1107', start=3740617, end=3740620, strand=1), - Location(locus='region1108', start=3740630, end=3740632, strand=1), - Location(locus='region1109', start=3740644, end=3740655, strand=1), - Location(locus='region1110', start=3740659, end=3740666, strand=1), - Location(locus='region1111', start=3740681, end=3740698, strand=1), - Location(locus='region1112', start=3740702, end=3740939, strand=1), - Location(locus='region1113', start=3741172, end=3741178, strand=1), - Location(locus='region1114', start=3741286, end=3741394, strand=1), - Location(locus='region1115', start=3741502, end=3741604, strand=1), - Location(locus='region1116', start=3741624, end=3741678, strand=1), - Location(locus='region1117', start=3741681, end=3741914, strand=1), - Location(locus='region1118', start=3741942, end=3742247, strand=1), - Location(locus='region1119', start=3742250, end=3742256, strand=1), - Location(locus='region1120', start=3742316, end=3742371, strand=1), - Location(locus='region1121', start=3743211, end=3743502, strand=1), - Location(locus='region1122', start=3743507, end=3743603, strand=1), - Location(locus='region1123', start=3743710, end=3753184, strand=1), - Location(locus='region1124', start=3753326, end=3754368, strand=1), - Location(locus='region1125', start=3756036, end=3756185, strand=1), - Location(locus='region1126', start=3756410, end=3756480, strand=1), - Location(locus='region1127', start=3756941, end=3757478, strand=1), - Location(locus='region1128', start=3757570, end=3757629, strand=1), - Location(locus='region1129', start=3757773, end=3757828, strand=1), - Location(locus='region1130', start=3757879, end=3757971, strand=1), - Location(locus='region1131', start=3757972, end=3758040, strand=1), - Location(locus='region1132', start=3758117, end=3758193, strand=1), - Location(locus='region1133', start=3758716, end=3759099, strand=1), - Location(locus='region1134', start=3759107, end=3759186, strand=1), - Location(locus='region1135', start=3759331, end=3759390, strand=1), - Location(locus='region1136', start=3759534, end=3759589, strand=1), - Location(locus='region1137', start=3759679, end=3759738, strand=1), - Location(locus='region1138', start=3759826, end=3759909, strand=1), - Location(locus='region1139', start=3760356, end=3760409, strand=1), - Location(locus='region1140', start=3760417, end=3760675, strand=1), - Location(locus='region1141', start=3760753, end=3760985, strand=1), - Location(locus='region1142', start=3762384, end=3762655, strand=1), - Location(locus='region1143', start=3762661, end=3762818, strand=1), - Location(locus='region1144', start=3763048, end=3763101, strand=1), - Location(locus='region1145', start=3763223, end=3763275, strand=1), - Location(locus='region1146', start=3763282, end=3763332, strand=1), - Location(locus='region1147', start=3764059, end=3764114, strand=1), - Location(locus='region1148', start=3764134, end=3764237, strand=1), - Location(locus='region1149', start=3764251, end=3764523, strand=1), - Location(locus='region1150', start=3764809, end=3764862, strand=1), - Location(locus='region1151', start=3764980, end=3765076, strand=1), - Location(locus='region1152', start=3765161, end=3765219, strand=1), - Location(locus='region1153', start=3765798, end=3765987, strand=1), - Location(locus='region1154', start=3766018, end=3766179, strand=1), - Location(locus='region1155', start=3766215, end=3766396, strand=1), - Location(locus='region1156', start=3766435, end=3766518, strand=1), - Location(locus='region1157', start=3766552, end=3766722, strand=1), - Location(locus='region1158', start=3766760, end=3766819, strand=1), - Location(locus='region1159', start=3766829, end=3767099, strand=1), - Location(locus='region1160', start=3769527, end=3769724, strand=1), - Location(locus='region1161', start=3769749, end=3769854, strand=1), - Location(locus='region1162', start=3770993, end=3771089, strand=1), - Location(locus='region1163', start=3779545, end=3779766, strand=1), - Location(locus='region1164', start=3779809, end=3779899, strand=1), - Location(locus='region1165', start=3779936, end=3779981, strand=1), - Location(locus='region1166', start=3780156, end=3780175, strand=1), - Location(locus='region1167', start=3794868, end=3796422, strand=1), - Location(locus='region1168', start=3800030, end=3800120, strand=1), - Location(locus='region1169', start=3801824, end=3801874, strand=1), - Location(locus='region1170', start=3802056, end=3802113, strand=1), - Location(locus='region1171', start=3802122, end=3803827, strand=1), - Location(locus='region1172', start=3803844, end=3803919, strand=1), - Location(locus='region1173', start=3808262, end=3808421, strand=1), - Location(locus='region1174', start=3820387, end=3820598, strand=1), - Location(locus='region1175', start=3820711, end=3820772, strand=1), - Location(locus='region1176', start=3835202, end=3835264, strand=1), - Location(locus='region1177', start=3841619, end=3842454, strand=1), - Location(locus='region1178', start=3842471, end=3842551, strand=1), - Location(locus='region1179', start=3842560, end=3842670, strand=1), - Location(locus='region1180', start=3842725, end=3842907, strand=1), - Location(locus='region1181', start=3842979, end=3843117, strand=1), - Location(locus='region1182', start=3843182, end=3843275, strand=1), - Location(locus='region1183', start=3843317, end=3843468, strand=1), - Location(locus='region1184', start=3843519, end=3843520, strand=1), - Location(locus='region1185', start=3843523, end=3843705, strand=1), - Location(locus='region1186', start=3843713, end=3843714, strand=1), - Location(locus='region1187', start=3843748, end=3843749, strand=1), - Location(locus='region1188', start=3843750, end=3843753, strand=1), - Location(locus='region1189', start=3843759, end=3843760, strand=1), - Location(locus='region1190', start=3844681, end=3844756, strand=1), - Location(locus='region1191', start=3845970, end=3847246, strand=1), - Location(locus='region1192', start=3847305, end=3847404, strand=1), - Location(locus='region1193', start=3847446, end=3847581, strand=1), - Location(locus='region1194', start=3847700, end=3847711, strand=1), - Location(locus='region1195', start=3847714, end=3847896, strand=1), - Location(locus='region1196', start=3862570, end=3862575, strand=1), - Location(locus='region1197', start=3862576, end=3862578, strand=1), - Location(locus='region1198', start=3873526, end=3873540, strand=1), - Location(locus='region1199', start=3878561, end=3878637, strand=1), - Location(locus='region1200', start=3883543, end=3884926, strand=1), - Location(locus='region1201', start=3890771, end=3892143, strand=1), - Location(locus='region1202', start=3894402, end=3894790, strand=1), - Location(locus='region1203', start=3894863, end=3895078, strand=1), - Location(locus='region1204', start=3895083, end=3895137, strand=1), - Location(locus='region1205', start=3895184, end=3895525, strand=1), - Location(locus='region1206', start=3909753, end=3909823, strand=1), - Location(locus='region1207', start=3920470, end=3920549, strand=1), - Location(locus='region1208', start=3926568, end=3930714, strand=1), - Location(locus='region1209', start=3930985, end=3936710, strand=1), - Location(locus='region1210', start=3939616, end=3944963, strand=1), - Location(locus='region1211', start=3945089, end=3945604, strand=1), - Location(locus='region1212', start=3945774, end=3950263, strand=1), - Location(locus='region1213', start=3950821, end=3951336, strand=1), - Location(locus='region1214', start=3953332, end=3953403, strand=1), - Location(locus='region1215', start=3971370, end=3971455, strand=1), - Location(locus='region1216', start=3971458, end=3971524, strand=1), - Location(locus='region1217', start=3971981, end=3972034, strand=1), - Location(locus='region1218', start=3972081, end=3972195, strand=1), - Location(locus='region1219', start=3972211, end=3972290, strand=1), - Location(locus='region1220', start=3972337, end=3972393, strand=1), - Location(locus='region1221', start=3991561, end=3991619, strand=1), - Location(locus='region1222', start=3998150, end=3998204, strand=1), - Location(locus='region1223', start=3998607, end=3998613, strand=1), - Location(locus='region1224', start=3998824, end=3998942, strand=1), - Location(locus='region1225', start=3998991, end=3999071, strand=1), - Location(locus='region1226', start=4021388, end=4021460, strand=1), - Location(locus='region1227', start=4031606, end=4031660, strand=1), - Location(locus='region1228', start=4031821, end=4031838, strand=1), - Location(locus='region1229', start=4031924, end=4031943, strand=1), - Location(locus='region1230', start=4031955, end=4032014, strand=1), - Location(locus='region1231', start=4032019, end=4032024, strand=1), - Location(locus='region1232', start=4032382, end=4032639, strand=1), - Location(locus='region1233', start=4032757, end=4032820, strand=1), - Location(locus='region1234', start=4036846, end=4037194, strand=1), - Location(locus='region1235', start=4037349, end=4037350, strand=1), - Location(locus='region1236', start=4037353, end=4037354, strand=1), - Location(locus='region1237', start=4037446, end=4037497, strand=1), - Location(locus='region1238', start=4037832, end=4037883, strand=1), - Location(locus='region1239', start=4038741, end=4038794, strand=1), - Location(locus='region1240', start=4038844, end=4038845, strand=1), - Location(locus='region1241', start=4038846, end=4038882, strand=1), - Location(locus='region1242', start=4039675, end=4039747, strand=1), - Location(locus='region1243', start=4040022, end=4040104, strand=1), - Location(locus='region1244', start=4052949, end=4053603, strand=1), - Location(locus='region1245', start=4053634, end=4053852, strand=1), - Location(locus='region1246', start=4059977, end=4060595, strand=1), - Location(locus='region1247', start=4061422, end=4061526, strand=1), - Location(locus='region1248', start=4070033, end=4070083, strand=1), - Location(locus='region1249', start=4070261, end=4070347, strand=1), - Location(locus='region1250', start=4077656, end=4077706, strand=1), - Location(locus='region1251', start=4077788, end=4077860, strand=1), - Location(locus='region1252', start=4077890, end=4077961, strand=1), - Location(locus='region1253', start=4077977, end=4078205, strand=1), - Location(locus='region1254', start=4087476, end=4087626, strand=1), - Location(locus='region1255', start=4090857, end=4090910, strand=1), - Location(locus='region1256', start=4091336, end=4091423, strand=1), - Location(locus='region1257', start=4094066, end=4094346, strand=1), - Location(locus='region1258', start=4101192, end=4101256, strand=1), - Location(locus='region1259', start=4107450, end=4107526, strand=1), - Location(locus='region1260', start=4120913, end=4121197, strand=1), - Location(locus='region1261', start=4134600, end=4134730, strand=1), - Location(locus='region1262', start=4139502, end=4139566, strand=1), - Location(locus='region1263', start=4139567, end=4139569, strand=1), - Location(locus='region1264', start=4143900, end=4143956, strand=1), - Location(locus='region1265', start=4155453, end=4155589, strand=1), - Location(locus='region1266', start=4156793, end=4156975, strand=1), - Location(locus='region1267', start=4168470, end=4168482, strand=1), - Location(locus='region1268', start=4175392, end=4175410, strand=1), - Location(locus='region1269', start=4189439, end=4189509, strand=1), - Location(locus='region1270', start=4190056, end=4190144, strand=1), - Location(locus='region1271', start=4199122, end=4199189, strand=1), - Location(locus='region1272', start=4201240, end=4201294, strand=1), - Location(locus='region1273', start=4216126, end=4216272, strand=1), - Location(locus='region1274', start=4216347, end=4216431, strand=1), - Location(locus='region1275', start=4216591, end=4216699, strand=1), - Location(locus='region1276', start=4221245, end=4221301, strand=1), - Location(locus='region1277', start=4221341, end=4221418, strand=1), - Location(locus='region1278', start=4221504, end=4221577, strand=1), - Location(locus='region1279', start=4221581, end=4221643, strand=1), - Location(locus='region1280', start=4221749, end=4221799, strand=1), - Location(locus='region1281', start=4222095, end=4222154, strand=1), - Location(locus='region1282', start=4222319, end=4222393, strand=1), - Location(locus='region1283', start=4222464, end=4222523, strand=1), - Location(locus='region1284', start=4222572, end=4222639, strand=1), - Location(locus='region1285', start=4231319, end=4232393, strand=1), - Location(locus='region1286', start=4237930, end=4237998, strand=1), - Location(locus='region1287', start=4240442, end=4240492, strand=1), - Location(locus='region1288', start=4247057, end=4247107, strand=1), - Location(locus='region1289', start=4252876, end=4254339, strand=1), - Location(locus='region1290', start=4265704, end=4265757, strand=1), - Location(locus='region1291', start=4266206, end=4266275, strand=1), - Location(locus='region1292', start=4266315, end=4266398, strand=1), - Location(locus='region1293', start=4266447, end=4266530, strand=1), - Location(locus='region1294', start=4288132, end=4288218, strand=1), - Location(locus='region1295', start=4293984, end=4294056, strand=1), - Location(locus='region1296', start=4294402, end=4294459, strand=1), - Location(locus='region1297', start=4294717, end=4294773, strand=1), - Location(locus='region1298', start=4296685, end=4296735, strand=1), - Location(locus='region1299', start=4297903, end=4297956, strand=1), - Location(locus='region1300', start=4301213, end=4301287, strand=1), - Location(locus='region1301', start=4301540, end=4301806, strand=1), - Location(locus='region1302', start=4301861, end=4302004, strand=1), - Location(locus='region1303', start=4302084, end=4302144, strand=1), - Location(locus='region1304', start=4302170, end=4302248, strand=1), - Location(locus='region1305', start=4302440, end=4302523, strand=1), - Location(locus='region1306', start=4302527, end=4302577, strand=1), - Location(locus='region1307', start=4302652, end=4302715, strand=1), - Location(locus='region1308', start=4302868, end=4302924, strand=1), - Location(locus='region1309', start=4302976, end=4303029, strand=1), - Location(locus='region1310', start=4303123, end=4303185, strand=1), - Location(locus='region1311', start=4303304, end=4303433, strand=1), - Location(locus='region1312', start=4317963, end=4318064, strand=1), - Location(locus='region1313', start=4318102, end=4318154, strand=1), - Location(locus='region1314', start=4318336, end=4319378, strand=1), - Location(locus='region1315', start=4320040, end=4320112, strand=1), - Location(locus='region1316', start=4340937, end=4340993, strand=1), - Location(locus='region1317', start=4348719, end=4348834, strand=1), - Location(locus='region1318', start=4353179, end=4353460, strand=1), - Location(locus='region1319', start=4353839, end=4353891, strand=1), - Location(locus='region1320', start=4359134, end=4359135, strand=1), - Location(locus='region1321', start=4361058, end=4361100, strand=1), - Location(locus='region1322', start=4368618, end=4368637, strand=1), - Location(locus='region1323', start=4369564, end=4369624, strand=1), - Location(locus='region1324', start=4383309, end=4383359, strand=1) + regions = [ + Location(locus="region1", start=23173, end=23238, strand=1), + Location(locus="region2", start=24720, end=24738, strand=1), + Location(locus="region3", start=39029, end=39030, strand=1), + Location(locus="region4", start=55548, end=55647, strand=1), + Location(locus="region5", start=71464, end=71584, strand=1), + Location(locus="region6", start=79499, end=83035, strand=1), + Location(locus="region7", start=86778, end=86779, strand=1), + Location(locus="region8", start=86780, end=86782, strand=1), + Location(locus="region9", start=103702, end=104811, strand=1), + Location(locus="region10", start=104813, end=105137, strand=1), + Location(locus="region11", start=131785, end=131844, strand=1), + Location(locus="region12", start=131928, end=131979, strand=1), + Location(locus="region13", start=131980, end=131982, strand=1), + Location(locus="region14", start=131992, end=131993, strand=1), + Location(locus="region15", start=132077, end=132079, strand=1), + Location(locus="region16", start=132159, end=132189, strand=1), + Location(locus="region17", start=132518, end=132684, strand=1), + Location(locus="region18", start=149499, end=149526, strand=1), + Location(locus="region19", start=149634, end=149760, strand=1), + Location(locus="region20", start=149825, end=150890, strand=1), + Location(locus="region21", start=154109, end=154245, strand=1), + Location(locus="region22", start=157278, end=157331, strand=1), + Location(locus="region23", start=157382, end=157433, strand=1), + Location(locus="region24", start=161526, end=161577, strand=1), + Location(locus="region25", start=171456, end=171457, strand=1), + Location(locus="region26", start=171778, end=171779, strand=1), + Location(locus="region27", start=177094, end=177180, strand=1), + Location(locus="region28", start=177225, end=177322, strand=1), + Location(locus="region29", start=177337, end=177408, strand=1), + Location(locus="region30", start=192336, end=192398, strand=1), + Location(locus="region31", start=197077, end=197130, strand=1), + Location(locus="region32", start=197191, end=197311, strand=1), + Location(locus="region33", start=197837, end=198006, strand=1), + Location(locus="region34", start=198089, end=198170, strand=1), + Location(locus="region35", start=198477, end=198537, strand=1), + Location(locus="region36", start=198936, end=199041, strand=1), + Location(locus="region37", start=199750, end=199832, strand=1), + Location(locus="region38", start=201952, end=202014, strand=1), + Location(locus="region39", start=206494, end=206519, strand=1), + Location(locus="region40", start=234446, end=234492, strand=1), + Location(locus="region41", start=253598, end=253666, strand=1), + Location(locus="region42", start=267757, end=267812, strand=1), + Location(locus="region43", start=272848, end=272957, strand=1), + Location(locus="region44", start=279525, end=279601, strand=1), + Location(locus="region45", start=293724, end=293792, strand=1), + Location(locus="region46", start=294285, end=294337, strand=1), + Location(locus="region47", start=308321, end=308413, strand=1), + Location(locus="region48", start=309084, end=309191, strand=1), + Location(locus="region49", start=309927, end=310110, strand=1), + Location(locus="region50", start=332699, end=333141, strand=1), + Location(locus="region51", start=333157, end=333223, strand=1), + Location(locus="region52", start=333292, end=333406, strand=1), + Location(locus="region53", start=333436, end=336385, strand=1), + Location(locus="region54", start=336399, end=336400, strand=1), + Location(locus="region55", start=336402, end=336403, strand=1), + Location(locus="region56", start=336404, end=336405, strand=1), + Location(locus="region57", start=336496, end=336497, strand=1), + Location(locus="region58", start=336503, end=336504, strand=1), + Location(locus="region59", start=336534, end=336535, strand=1), + Location(locus="region60", start=336536, end=336537, strand=1), + Location(locus="region61", start=336539, end=336540, strand=1), + Location(locus="region62", start=336545, end=336546, strand=1), + Location(locus="region63", start=336552, end=337173, strand=1), + Location(locus="region64", start=337265, end=337381, strand=1), + Location(locus="region65", start=337492, end=337617, strand=1), + Location(locus="region66", start=337714, end=339148, strand=1), + Location(locus="region67", start=339715, end=339822, strand=1), + Location(locus="region68", start=340429, end=340470, strand=1), + Location(locus="region69", start=340472, end=340484, strand=1), + Location(locus="region70", start=341205, end=341267, strand=1), + Location(locus="region71", start=350296, end=350360, strand=1), + Location(locus="region72", start=351570, end=351659, strand=1), + Location(locus="region73", start=351890, end=351940, strand=1), + Location(locus="region74", start=361634, end=361726, strand=1), + Location(locus="region75", start=361740, end=361973, strand=1), + Location(locus="region76", start=361987, end=362010, strand=1), + Location(locus="region77", start=362620, end=362748, strand=1), + Location(locus="region78", start=362751, end=362764, strand=1), + Location(locus="region79", start=362769, end=362916, strand=1), + Location(locus="region80", start=362960, end=363020, strand=1), + Location(locus="region81", start=366149, end=372764, strand=1), + Location(locus="region82", start=372777, end=372834, strand=1), + Location(locus="region83", start=373194, end=373249, strand=1), + Location(locus="region84", start=373280, end=373372, strand=1), + Location(locus="region85", start=373394, end=373471, strand=1), + Location(locus="region86", start=373527, end=373657, strand=1), + Location(locus="region87", start=373972, end=374026, strand=1), + Location(locus="region88", start=374051, end=374185, strand=1), + Location(locus="region89", start=374464, end=374983, strand=1), + Location(locus="region90", start=375259, end=375329, strand=1), + Location(locus="region91", start=400147, end=401706, strand=1), + Location(locus="region92", start=410552, end=410570, strand=1), + Location(locus="region93", start=424007, end=424150, strand=1), + Location(locus="region94", start=424843, end=425033, strand=1), + Location(locus="region95", start=425096, end=425154, strand=1), + Location(locus="region96", start=425168, end=425272, strand=1), + Location(locus="region97", start=425284, end=425410, strand=1), + Location(locus="region98", start=425411, end=425593, strand=1), + Location(locus="region99", start=426576, end=426680, strand=1), + Location(locus="region100", start=426736, end=426861, strand=1), + Location(locus="region101", start=426910, end=426998, strand=1), + Location(locus="region102", start=427070, end=427200, strand=1), + Location(locus="region103", start=427296, end=427383, strand=1), + Location(locus="region104", start=428403, end=428503, strand=1), + Location(locus="region105", start=428525, end=428762, strand=1), + Location(locus="region106", start=429119, end=429181, strand=1), + Location(locus="region107", start=429632, end=429716, strand=1), + Location(locus="region108", start=429791, end=430174, strand=1), + Location(locus="region109", start=431043, end=431094, strand=1), + Location(locus="region110", start=431126, end=431184, strand=1), + Location(locus="region111", start=431192, end=431263, strand=1), + Location(locus="region112", start=431273, end=431442, strand=1), + Location(locus="region113", start=431454, end=431551, strand=1), + Location(locus="region114", start=431884, end=431935, strand=1), + Location(locus="region115", start=432375, end=432436, strand=1), + Location(locus="region116", start=432533, end=432592, strand=1), + Location(locus="region117", start=432605, end=432804, strand=1), + Location(locus="region118", start=433691, end=433801, strand=1), + Location(locus="region119", start=433848, end=433930, strand=1), + Location(locus="region120", start=433940, end=434006, strand=1), + Location(locus="region121", start=434227, end=434311, strand=1), + Location(locus="region122", start=456207, end=456210, strand=1), + Location(locus="region123", start=456211, end=456212, strand=1), + Location(locus="region124", start=459877, end=459930, strand=1), + Location(locus="region125", start=460997, end=461069, strand=1), + Location(locus="region126", start=461350, end=461432, strand=1), + Location(locus="region127", start=472443, end=472496, strand=1), + Location(locus="region128", start=473741, end=474045, strand=1), + Location(locus="region129", start=474047, end=474109, strand=1), + Location(locus="region130", start=475807, end=476111, strand=1), + Location(locus="region131", start=476125, end=476183, strand=1), + Location(locus="region132", start=488167, end=488222, strand=1), + Location(locus="region133", start=496254, end=496354, strand=1), + Location(locus="region134", start=531536, end=531591, strand=1), + Location(locus="region135", start=538775, end=538840, strand=1), + Location(locus="region136", start=543555, end=543639, strand=1), + Location(locus="region137", start=560891, end=560941, strand=1), + Location(locus="region138", start=561274, end=561339, strand=1), + Location(locus="region139", start=561532, end=561658, strand=1), + Location(locus="region140", start=562303, end=562397, strand=1), + Location(locus="region141", start=566271, end=566345, strand=1), + Location(locus="region142", start=569811, end=569985, strand=1), + Location(locus="region143", start=577281, end=577503, strand=1), + Location(locus="region144", start=580566, end=580821, strand=1), + Location(locus="region145", start=594517, end=594569, strand=1), + Location(locus="region146", start=595330, end=595453, strand=1), + Location(locus="region147", start=598879, end=598932, strand=1), + Location(locus="region148", start=606506, end=608064, strand=1), + Location(locus="region149", start=622890, end=622945, strand=1), + Location(locus="region150", start=623098, end=624417, strand=1), + Location(locus="region151", start=631282, end=631440, strand=1), + Location(locus="region152", start=642735, end=642818, strand=1), + Location(locus="region153", start=663428, end=663429, strand=1), + Location(locus="region154", start=669263, end=669314, strand=1), + Location(locus="region155", start=672009, end=672011, strand=1), + Location(locus="region156", start=672014, end=672070, strand=1), + Location(locus="region157", start=672104, end=672108, strand=1), + Location(locus="region158", start=672161, end=672246, strand=1), + Location(locus="region159", start=672265, end=672274, strand=1), + Location(locus="region160", start=672443, end=672462, strand=1), + Location(locus="region161", start=672477, end=672524, strand=1), + Location(locus="region162", start=672532, end=672563, strand=1), + Location(locus="region163", start=672648, end=672805, strand=1), + Location(locus="region164", start=672827, end=672919, strand=1), + Location(locus="region165", start=672945, end=672951, strand=1), + Location(locus="region166", start=672955, end=672959, strand=1), + Location(locus="region167", start=673102, end=673134, strand=1), + Location(locus="region168", start=673135, end=673623, strand=1), + Location(locus="region169", start=673635, end=673637, strand=1), + Location(locus="region170", start=673647, end=673668, strand=1), + Location(locus="region171", start=673940, end=673995, strand=1), + Location(locus="region172", start=674121, end=674132, strand=1), + Location(locus="region173", start=674142, end=674163, strand=1), + Location(locus="region174", start=674218, end=674220, strand=1), + Location(locus="region175", start=674227, end=674233, strand=1), + Location(locus="region176", start=674240, end=674272, strand=1), + Location(locus="region177", start=674311, end=674319, strand=1), + Location(locus="region178", start=674343, end=674358, strand=1), + Location(locus="region179", start=674434, end=674507, strand=1), + Location(locus="region180", start=674546, end=674556, strand=1), + Location(locus="region181", start=674780, end=675029, strand=1), + Location(locus="region182", start=675034, end=675405, strand=1), + Location(locus="region183", start=675486, end=675548, strand=1), + Location(locus="region184", start=675555, end=675615, strand=1), + Location(locus="region185", start=677064, end=677128, strand=1), + Location(locus="region186", start=685345, end=685398, strand=1), + Location(locus="region187", start=685459, end=685579, strand=1), + Location(locus="region188", start=686123, end=686292, strand=1), + Location(locus="region189", start=686375, end=686456, strand=1), + Location(locus="region190", start=686763, end=686823, strand=1), + Location(locus="region191", start=687245, end=687325, strand=1), + Location(locus="region192", start=687887, end=687969, strand=1), + Location(locus="region193", start=690079, end=690141, strand=1), + Location(locus="region194", start=699610, end=699640, strand=1), + Location(locus="region195", start=701242, end=701311, strand=1), + Location(locus="region196", start=701313, end=701438, strand=1), + Location(locus="region197", start=702055, end=702169, strand=1), + Location(locus="region198", start=702279, end=702358, strand=1), + Location(locus="region199", start=702538, end=702627, strand=1), + Location(locus="region200", start=709420, end=709489, strand=1), + Location(locus="region201", start=709492, end=709544, strand=1), + Location(locus="region202", start=709581, end=709666, strand=1), + Location(locus="region203", start=711563, end=711705, strand=1), + Location(locus="region204", start=716627, end=716678, strand=1), + Location(locus="region205", start=717242, end=717295, strand=1), + Location(locus="region206", start=717640, end=717717, strand=1), + Location(locus="region207", start=718309, end=718366, strand=1), + Location(locus="region208", start=718811, end=718863, strand=1), + Location(locus="region209", start=718864, end=718926, strand=1), + Location(locus="region210", start=719128, end=719200, strand=1), + Location(locus="region211", start=719383, end=719465, strand=1), + Location(locus="region212", start=719466, end=719546, strand=1), + Location(locus="region213", start=719637, end=719688, strand=1), + Location(locus="region214", start=725208, end=725233, strand=1), + Location(locus="region215", start=735079, end=735081, strand=1), + Location(locus="region216", start=736226, end=736298, strand=1), + Location(locus="region217", start=737308, end=737390, strand=1), + Location(locus="region218", start=737989, end=738061, strand=1), + Location(locus="region219", start=738337, end=738419, strand=1), + Location(locus="region220", start=738723, end=738788, strand=1), + Location(locus="region221", start=738922, end=738974, strand=1), + Location(locus="region222", start=738981, end=739052, strand=1), + Location(locus="region223", start=739053, end=739144, strand=1), + Location(locus="region224", start=742562, end=742638, strand=1), + Location(locus="region225", start=747949, end=748000, strand=1), + Location(locus="region226", start=755259, end=755331, strand=1), + Location(locus="region227", start=767365, end=767366, strand=1), + Location(locus="region228", start=767367, end=767371, strand=1), + Location(locus="region229", start=776715, end=776768, strand=1), + Location(locus="region230", start=786025, end=786081, strand=1), + Location(locus="region231", start=795468, end=795527, strand=1), + Location(locus="region232", start=798663, end=798739, strand=1), + Location(locus="region233", start=798998, end=799069, strand=1), + Location(locus="region234", start=806193, end=806194, strand=1), + Location(locus="region235", start=806195, end=806199, strand=1), + Location(locus="region236", start=806202, end=806219, strand=1), + Location(locus="region237", start=812848, end=812898, strand=1), + Location(locus="region238", start=818308, end=818358, strand=1), + Location(locus="region239", start=829702, end=829773, strand=1), + Location(locus="region240", start=830629, end=830685, strand=1), + Location(locus="region241", start=830712, end=830765, strand=1), + Location(locus="region242", start=831188, end=831263, strand=1), + Location(locus="region243", start=831965, end=832028, strand=1), + Location(locus="region244", start=832083, end=832362, strand=1), + Location(locus="region245", start=832654, end=832758, strand=1), + Location(locus="region246", start=832980, end=833508, strand=1), + Location(locus="region247", start=833514, end=833517, strand=1), + Location(locus="region248", start=833529, end=833539, strand=1), + Location(locus="region249", start=835080, end=835203, strand=1), + Location(locus="region250", start=835405, end=835458, strand=1), + Location(locus="region251", start=835700, end=838052, strand=1), + Location(locus="region252", start=838450, end=840856, strand=1), + Location(locus="region253", start=840959, end=841073, strand=1), + Location(locus="region254", start=841142, end=841208, strand=1), + Location(locus="region255", start=841224, end=841666, strand=1), + Location(locus="region256", start=841941, end=842016, strand=1), + Location(locus="region257", start=842058, end=842470, strand=1), + Location(locus="region258", start=844884, end=844888, strand=1), + Location(locus="region259", start=846903, end=846905, strand=1), + Location(locus="region260", start=849912, end=849965, strand=1), + Location(locus="region261", start=863185, end=863260, strand=1), + Location(locus="region262", start=888762, end=891466, strand=1), + Location(locus="region263", start=908176, end=909351, strand=1), + Location(locus="region264", start=917606, end=917740, strand=1), + Location(locus="region265", start=921573, end=921897, strand=1), + Location(locus="region266", start=925070, end=925133, strand=1), + Location(locus="region267", start=925262, end=926393, strand=1), + Location(locus="region268", start=926515, end=926596, strand=1), + Location(locus="region269", start=926626, end=927518, strand=1), + Location(locus="region270", start=927890, end=927940, strand=1), + Location(locus="region271", start=928675, end=928791, strand=1), + Location(locus="region272", start=928868, end=928936, strand=1), + Location(locus="region273", start=929015, end=929360, strand=1), + Location(locus="region274", start=929367, end=929373, strand=1), + Location(locus="region275", start=929463, end=929470, strand=1), + Location(locus="region276", start=929476, end=929605, strand=1), + Location(locus="region277", start=929666, end=929961, strand=1), + Location(locus="region278", start=958454, end=958522, strand=1), + Location(locus="region279", start=960161, end=960332, strand=1), + Location(locus="region280", start=964577, end=965082, strand=1), + Location(locus="region281", start=968779, end=968829, strand=1), + Location(locus="region282", start=969615, end=969752, strand=1), + Location(locus="region283", start=969874, end=969934, strand=1), + Location(locus="region284", start=972605, end=972657, strand=1), + Location(locus="region285", start=972658, end=972720, strand=1), + Location(locus="region286", start=972922, end=972994, strand=1), + Location(locus="region287", start=973177, end=973259, strand=1), + Location(locus="region288", start=973260, end=973340, strand=1), + Location(locus="region289", start=973431, end=973482, strand=1), + Location(locus="region290", start=973762, end=973786, strand=1), + Location(locus="region291", start=976897, end=976913, strand=1), + Location(locus="region292", start=977517, end=977570, strand=1), + Location(locus="region293", start=977979, end=978031, strand=1), + Location(locus="region294", start=978087, end=978143, strand=1), + Location(locus="region295", start=996027, end=996089, strand=1), + Location(locus="region296", start=1000741, end=1000799, strand=1), + Location(locus="region297", start=1025867, end=1025899, strand=1), + Location(locus="region298", start=1025901, end=1025904, strand=1), + Location(locus="region299", start=1056823, end=1056824, strand=1), + Location(locus="region300", start=1056825, end=1056829, strand=1), + Location(locus="region301", start=1064047, end=1064118, strand=1), + Location(locus="region302", start=1066998, end=1067002, strand=1), + Location(locus="region303", start=1070325, end=1070330, strand=1), + Location(locus="region304", start=1071258, end=1071318, strand=1), + Location(locus="region305", start=1090782, end=1090783, strand=1), + Location(locus="region306", start=1090788, end=1090789, strand=1), + Location(locus="region307", start=1090790, end=1090793, strand=1), + Location(locus="region308", start=1090803, end=1090814, strand=1), + Location(locus="region309", start=1090938, end=1090940, strand=1), + Location(locus="region310", start=1090957, end=1091137, strand=1), + Location(locus="region311", start=1091147, end=1091152, strand=1), + Location(locus="region312", start=1091362, end=1091368, strand=1), + Location(locus="region313", start=1091373, end=1091379, strand=1), + Location(locus="region314", start=1091388, end=1091846, strand=1), + Location(locus="region315", start=1091888, end=1092021, strand=1), + Location(locus="region316", start=1092056, end=1092089, strand=1), + Location(locus="region317", start=1092102, end=1092104, strand=1), + Location(locus="region318", start=1092246, end=1092263, strand=1), + Location(locus="region319", start=1093232, end=1093320, strand=1), + Location(locus="region320", start=1093450, end=1093647, strand=1), + Location(locus="region321", start=1093650, end=1094593, strand=1), + Location(locus="region322", start=1094865, end=1094953, strand=1), + Location(locus="region323", start=1095203, end=1095325, strand=1), + Location(locus="region324", start=1095331, end=1096699, strand=1), + Location(locus="region325", start=1121040, end=1121090, strand=1), + Location(locus="region326", start=1121121, end=1121171, strand=1), + Location(locus="region327", start=1121657, end=1121731, strand=1), + Location(locus="region328", start=1133280, end=1133283, strand=1), + Location(locus="region329", start=1145287, end=1145317, strand=1), + Location(locus="region330", start=1159195, end=1159245, strand=1), + Location(locus="region331", start=1160331, end=1160421, strand=1), + Location(locus="region332", start=1160537, end=1161159, strand=1), + Location(locus="region333", start=1161301, end=1161365, strand=1), + Location(locus="region334", start=1162562, end=1162612, strand=1), + Location(locus="region335", start=1164564, end=1165555, strand=1), + Location(locus="region336", start=1169292, end=1170739, strand=1), + Location(locus="region337", start=1179346, end=1179397, strand=1), + Location(locus="region338", start=1182321, end=1182382, strand=1), + Location(locus="region339", start=1188518, end=1188908, strand=1), + Location(locus="region340", start=1188949, end=1188955, strand=1), + Location(locus="region341", start=1188972, end=1189047, strand=1), + Location(locus="region342", start=1189073, end=1189075, strand=1), + Location(locus="region343", start=1189081, end=1189157, strand=1), + Location(locus="region344", start=1189158, end=1190177, strand=1), + Location(locus="region345", start=1190249, end=1190299, strand=1), + Location(locus="region346", start=1190854, end=1190944, strand=1), + Location(locus="region347", start=1190969, end=1191112, strand=1), + Location(locus="region348", start=1191130, end=1191221, strand=1), + Location(locus="region349", start=1191248, end=1191901, strand=1), + Location(locus="region350", start=1200523, end=1200544, strand=1), + Location(locus="region351", start=1203334, end=1203396, strand=1), + Location(locus="region352", start=1211559, end=1213863, strand=1), + Location(locus="region353", start=1216548, end=1216649, strand=1), + Location(locus="region354", start=1216717, end=1216769, strand=1), + Location(locus="region355", start=1216817, end=1216921, strand=1), + Location(locus="region356", start=1216922, end=1217162, strand=1), + Location(locus="region357", start=1217167, end=1217181, strand=1), + Location(locus="region358", start=1217416, end=1217422, strand=1), + Location(locus="region359", start=1217423, end=1218426, strand=1), + Location(locus="region360", start=1218436, end=1218676, strand=1), + Location(locus="region361", start=1218702, end=1218703, strand=1), + Location(locus="region362", start=1218968, end=1218970, strand=1), + Location(locus="region363", start=1224338, end=1224340, strand=1), + Location(locus="region364", start=1224341, end=1224345, strand=1), + Location(locus="region365", start=1224348, end=1224350, strand=1), + Location(locus="region366", start=1224356, end=1224357, strand=1), + Location(locus="region367", start=1230571, end=1230648, strand=1), + Location(locus="region368", start=1251678, end=1251752, strand=1), + Location(locus="region369", start=1262918, end=1263031, strand=1), + Location(locus="region370", start=1263084, end=1263190, strand=1), + Location(locus="region371", start=1263707, end=1263760, strand=1), + Location(locus="region372", start=1267219, end=1267269, strand=1), + Location(locus="region373", start=1275555, end=1275607, strand=1), + Location(locus="region374", start=1275922, end=1276056, strand=1), + Location(locus="region375", start=1276289, end=1278829, strand=1), + Location(locus="region376", start=1281895, end=1282022, strand=1), + Location(locus="region377", start=1283487, end=1283493, strand=1), + Location(locus="region378", start=1283512, end=1283548, strand=1), + Location(locus="region379", start=1283554, end=1283562, strand=1), + Location(locus="region380", start=1284407, end=1284473, strand=1), + Location(locus="region381", start=1284491, end=1284557, strand=1), + Location(locus="region382", start=1287559, end=1287627, strand=1), + Location(locus="region383", start=1287810, end=1288095, strand=1), + Location(locus="region384", start=1293002, end=1293070, strand=1), + Location(locus="region385", start=1305490, end=1305665, strand=1), + Location(locus="region386", start=1313129, end=1313134, strand=1), + Location(locus="region387", start=1313384, end=1313385, strand=1), + Location(locus="region388", start=1313389, end=1313394, strand=1), + Location(locus="region389", start=1319185, end=1319262, strand=1), + Location(locus="region390", start=1326283, end=1326333, strand=1), + Location(locus="region391", start=1335476, end=1335507, strand=1), + Location(locus="region392", start=1335508, end=1335513, strand=1), + Location(locus="region393", start=1339343, end=1339839, strand=1), + Location(locus="region394", start=1339886, end=1340001, strand=1), + Location(locus="region395", start=1340006, end=1340060, strand=1), + Location(locus="region396", start=1340061, end=1340397, strand=1), + Location(locus="region397", start=1340491, end=1342739, strand=1), + Location(locus="region398", start=1351194, end=1351283, strand=1), + Location(locus="region399", start=1357060, end=1357129, strand=1), + Location(locus="region400", start=1357247, end=1357302, strand=1), + Location(locus="region401", start=1363470, end=1363471, strand=1), + Location(locus="region402", start=1385096, end=1385437, strand=1), + Location(locus="region403", start=1385572, end=1385580, strand=1), + Location(locus="region404", start=1385586, end=1385667, strand=1), + Location(locus="region405", start=1385669, end=1385672, strand=1), + Location(locus="region406", start=1386008, end=1386036, strand=1), + Location(locus="region407", start=1386073, end=1386081, strand=1), + Location(locus="region408", start=1386112, end=1386113, strand=1), + Location(locus="region409", start=1386118, end=1386121, strand=1), + Location(locus="region410", start=1386125, end=1386129, strand=1), + Location(locus="region411", start=1386136, end=1386140, strand=1), + Location(locus="region412", start=1386154, end=1386214, strand=1), + Location(locus="region413", start=1386285, end=1386359, strand=1), + Location(locus="region414", start=1386451, end=1386501, strand=1), + Location(locus="region415", start=1388110, end=1388170, strand=1), + Location(locus="region416", start=1408678, end=1408729, strand=1), + Location(locus="region417", start=1414620, end=1414621, strand=1), + Location(locus="region418", start=1414628, end=1414629, strand=1), + Location(locus="region419", start=1414643, end=1414644, strand=1), + Location(locus="region420", start=1414652, end=1414653, strand=1), + Location(locus="region421", start=1441364, end=1441725, strand=1), + Location(locus="region422", start=1443427, end=1443428, strand=1), + Location(locus="region423", start=1443433, end=1443486, strand=1), + Location(locus="region424", start=1445086, end=1445117, strand=1), + Location(locus="region425", start=1445118, end=1445121, strand=1), + Location(locus="region426", start=1451772, end=1452003, strand=1), + Location(locus="region427", start=1456572, end=1456625, strand=1), + Location(locus="region428", start=1457459, end=1457568, strand=1), + Location(locus="region429", start=1468160, end=1469623, strand=1), + Location(locus="region430", start=1479348, end=1479409, strand=1), + Location(locus="region431", start=1479487, end=1479538, strand=1), + Location(locus="region432", start=1479716, end=1479925, strand=1), + Location(locus="region433", start=1480944, end=1480945, strand=1), + Location(locus="region434", start=1480947, end=1481670, strand=1), + Location(locus="region435", start=1482823, end=1482878, strand=1), + Location(locus="region436", start=1483109, end=1483165, strand=1), + Location(locus="region437", start=1483196, end=1483254, strand=1), + Location(locus="region438", start=1483264, end=1483318, strand=1), + Location(locus="region439", start=1488082, end=1488147, strand=1), + Location(locus="region440", start=1488383, end=1488410, strand=1), + Location(locus="region441", start=1488413, end=1488420, strand=1), + Location(locus="region442", start=1488429, end=1488757, strand=1), + Location(locus="region443", start=1488760, end=1488766, strand=1), + Location(locus="region444", start=1488776, end=1488788, strand=1), + Location(locus="region445", start=1488791, end=1488794, strand=1), + Location(locus="region446", start=1488807, end=1488810, strand=1), + Location(locus="region447", start=1488813, end=1488839, strand=1), + Location(locus="region448", start=1488843, end=1488848, strand=1), + Location(locus="region449", start=1488896, end=1489512, strand=1), + Location(locus="region450", start=1489537, end=1489647, strand=1), + Location(locus="region451", start=1489738, end=1489798, strand=1), + Location(locus="region452", start=1524571, end=1524574, strand=1), + Location(locus="region453", start=1532535, end=1532922, strand=1), + Location(locus="region454", start=1532986, end=1533658, strand=1), + Location(locus="region455", start=1541944, end=1543431, strand=1), + Location(locus="region456", start=1543453, end=1543457, strand=1), + Location(locus="region457", start=1543462, end=1543480, strand=1), + Location(locus="region458", start=1568048, end=1568106, strand=1), + Location(locus="region459", start=1572184, end=1572482, strand=1), + Location(locus="region460", start=1572499, end=1572621, strand=1), + Location(locus="region461", start=1572744, end=1573530, strand=1), + Location(locus="region462", start=1573555, end=1573606, strand=1), + Location(locus="region463", start=1606514, end=1606565, strand=1), + Location(locus="region464", start=1612562, end=1612665, strand=1), + Location(locus="region465", start=1618208, end=1619684, strand=1), + Location(locus="region466", start=1625354, end=1625422, strand=1), + Location(locus="region467", start=1630814, end=1630825, strand=1), + Location(locus="region468", start=1630827, end=1630837, strand=1), + Location(locus="region469", start=1630839, end=1630872, strand=1), + Location(locus="region470", start=1630874, end=1630875, strand=1), + Location(locus="region471", start=1630996, end=1631117, strand=1), + Location(locus="region472", start=1631391, end=1631908, strand=1), + Location(locus="region473", start=1631936, end=1631955, strand=1), + Location(locus="region474", start=1632057, end=1632128, strand=1), + Location(locus="region475", start=1632218, end=1632220, strand=1), + Location(locus="region476", start=1632231, end=1632289, strand=1), + Location(locus="region477", start=1632355, end=1632824, strand=1), + Location(locus="region478", start=1632856, end=1632858, strand=1), + Location(locus="region479", start=1633191, end=1634797, strand=1), + Location(locus="region480", start=1636003, end=1638399, strand=1), + Location(locus="region481", start=1644242, end=1644372, strand=1), + Location(locus="region482", start=1654154, end=1654206, strand=1), + Location(locus="region483", start=1655670, end=1655721, strand=1), + Location(locus="region484", start=1655814, end=1655815, strand=1), + Location(locus="region485", start=1656096, end=1656098, strand=1), + Location(locus="region486", start=1656099, end=1656208, strand=1), + Location(locus="region487", start=1656328, end=1656410, strand=1), + Location(locus="region488", start=1656516, end=1656596, strand=1), + Location(locus="region489", start=1672405, end=1672466, strand=1), + Location(locus="region490", start=1678950, end=1679019, strand=1), + Location(locus="region491", start=1685477, end=1685546, strand=1), + Location(locus="region492", start=1699863, end=1699920, strand=1), + Location(locus="region493", start=1702156, end=1702206, strand=1), + Location(locus="region494", start=1702384, end=1702470, strand=1), + Location(locus="region495", start=1702676, end=1702854, strand=1), + Location(locus="region496", start=1703071, end=1703128, strand=1), + Location(locus="region497", start=1710884, end=1710945, strand=1), + Location(locus="region498", start=1712842, end=1712892, strand=1), + Location(locus="region499", start=1713497, end=1713547, strand=1), + Location(locus="region500", start=1713673, end=1713753, strand=1), + Location(locus="region501", start=1722650, end=1722700, strand=1), + Location(locus="region502", start=1722809, end=1722890, strand=1), + Location(locus="region503", start=1723227, end=1723284, strand=1), + Location(locus="region504", start=1723515, end=1723595, strand=1), + Location(locus="region505", start=1725516, end=1725566, strand=1), + Location(locus="region506", start=1730045, end=1730095, strand=1), + Location(locus="region507", start=1730876, end=1730956, strand=1), + Location(locus="region508", start=1731135, end=1731203, strand=1), + Location(locus="region509", start=1735541, end=1735635, strand=1), + Location(locus="region510", start=1753012, end=1753062, strand=1), + Location(locus="region511", start=1753287, end=1753337, strand=1), + Location(locus="region512", start=1773952, end=1774109, strand=1), + Location(locus="region513", start=1779266, end=1789872, strand=1), + Location(locus="region514", start=1814850, end=1815130, strand=1), + Location(locus="region515", start=1828800, end=1828860, strand=1), + Location(locus="region516", start=1830066, end=1830125, strand=1), + Location(locus="region517", start=1863481, end=1863575, strand=1), + Location(locus="region518", start=1863723, end=1863733, strand=1), + Location(locus="region519", start=1864008, end=1864112, strand=1), + Location(locus="region520", start=1864256, end=1864323, strand=1), + Location(locus="region521", start=1864394, end=1864468, strand=1), + Location(locus="region522", start=1864554, end=1864567, strand=1), + Location(locus="region523", start=1864568, end=1864580, strand=1), + Location(locus="region524", start=1864702, end=1864872, strand=1), + Location(locus="region525", start=1864885, end=1864924, strand=1), + Location(locus="region526", start=1865012, end=1865070, strand=1), + Location(locus="region527", start=1875415, end=1875504, strand=1), + Location(locus="region528", start=1875877, end=1875967, strand=1), + Location(locus="region529", start=1876150, end=1876234, strand=1), + Location(locus="region530", start=1876404, end=1876592, strand=1), + Location(locus="region531", start=1876600, end=1876674, strand=1), + Location(locus="region532", start=1879287, end=1879381, strand=1), + Location(locus="region533", start=1879425, end=1879426, strand=1), + Location(locus="region534", start=1879494, end=1879503, strand=1), + Location(locus="region535", start=1879504, end=1879619, strand=1), + Location(locus="region536", start=1879631, end=1879638, strand=1), + Location(locus="region537", start=1879650, end=1879659, strand=1), + Location(locus="region538", start=1880680, end=1880748, strand=1), + Location(locus="region539", start=1880756, end=1880809, strand=1), + Location(locus="region540", start=1880823, end=1880877, strand=1), + Location(locus="region541", start=1880884, end=1880943, strand=1), + Location(locus="region542", start=1881812, end=1881901, strand=1), + Location(locus="region543", start=1882244, end=1882358, strand=1), + Location(locus="region544", start=1882541, end=1882625, strand=1), + Location(locus="region545", start=1882694, end=1882760, strand=1), + Location(locus="region546", start=1882792, end=1882979, strand=1), + Location(locus="region547", start=1882988, end=1883062, strand=1), + Location(locus="region548", start=1883354, end=1883404, strand=1), + Location(locus="region549", start=1885850, end=1885902, strand=1), + Location(locus="region550", start=1886335, end=1886387, strand=1), + Location(locus="region551", start=1886690, end=1886751, strand=1), + Location(locus="region552", start=1886989, end=1887057, strand=1), + Location(locus="region553", start=1887065, end=1887118, strand=1), + Location(locus="region554", start=1887132, end=1887186, strand=1), + Location(locus="region555", start=1887193, end=1887252, strand=1), + Location(locus="region556", start=1889505, end=1889555, strand=1), + Location(locus="region557", start=1895347, end=1895599, strand=1), + Location(locus="region558", start=1907452, end=1907583, strand=1), + Location(locus="region559", start=1914970, end=1914986, strand=1), + Location(locus="region560", start=1914987, end=1914995, strand=1), + Location(locus="region561", start=1914998, end=1914999, strand=1), + Location(locus="region562", start=1933297, end=1933384, strand=1), + Location(locus="region563", start=1933712, end=1933762, strand=1), + Location(locus="region564", start=1946846, end=1947027, strand=1), + Location(locus="region565", start=1955433, end=1955483, strand=1), + Location(locus="region566", start=1955581, end=1955615, strand=1), + Location(locus="region567", start=1955638, end=1955672, strand=1), + Location(locus="region568", start=1963153, end=1963221, strand=1), + Location(locus="region569", start=1963420, end=1963705, strand=1), + Location(locus="region570", start=1963888, end=1963956, strand=1), + Location(locus="region571", start=1967880, end=1967931, strand=1), + Location(locus="region572", start=1971233, end=1971334, strand=1), + Location(locus="region573", start=1981613, end=1984775, strand=1), + Location(locus="region574", start=1987173, end=1987241, strand=1), + Location(locus="region575", start=1987344, end=1987406, strand=1), + Location(locus="region576", start=1987693, end=1989068, strand=1), + Location(locus="region577", start=1989894, end=1989972, strand=1), + Location(locus="region578", start=1989982, end=1990093, strand=1), + Location(locus="region579", start=1990109, end=1990114, strand=1), + Location(locus="region580", start=1990322, end=1990823, strand=1), + Location(locus="region581", start=1991181, end=1991480, strand=1), + Location(locus="region582", start=1991569, end=1992029, strand=1), + Location(locus="region583", start=1992054, end=1992111, strand=1), + Location(locus="region584", start=1992282, end=1992334, strand=1), + Location(locus="region585", start=1996092, end=1998618, strand=1), + Location(locus="region586", start=2000924, end=2000998, strand=1), + Location(locus="region587", start=2001009, end=2001062, strand=1), + Location(locus="region588", start=2001205, end=2001716, strand=1), + Location(locus="region589", start=2002029, end=2002036, strand=1), + Location(locus="region590", start=2002125, end=2002328, strand=1), + Location(locus="region591", start=2002405, end=2002406, strand=1), + Location(locus="region592", start=2025296, end=2025858, strand=1), + Location(locus="region593", start=2025891, end=2026167, strand=1), + Location(locus="region594", start=2028420, end=2029246, strand=1), + Location(locus="region595", start=2030328, end=2030648, strand=1), + Location(locus="region596", start=2030703, end=2030986, strand=1), + Location(locus="region597", start=2039731, end=2039781, strand=1), + Location(locus="region598", start=2043797, end=2043858, strand=1), + Location(locus="region599", start=2045048, end=2045107, strand=1), + Location(locus="region600", start=2045963, end=2045964, strand=1), + Location(locus="region601", start=2045969, end=2045970, strand=1), + Location(locus="region602", start=2046100, end=2046195, strand=1), + Location(locus="region603", start=2047627, end=2047721, strand=1), + Location(locus="region604", start=2048789, end=2048842, strand=1), + Location(locus="region605", start=2050287, end=2050398, strand=1), + Location(locus="region606", start=2059425, end=2059608, strand=1), + Location(locus="region607", start=2061412, end=2061430, strand=1), + Location(locus="region608", start=2061431, end=2062159, strand=1), + Location(locus="region609", start=2062286, end=2062369, strand=1), + Location(locus="region610", start=2062448, end=2062515, strand=1), + Location(locus="region611", start=2069016, end=2069069, strand=1), + Location(locus="region612", start=2074430, end=2074840, strand=1), + Location(locus="region613", start=2088461, end=2088499, strand=1), + Location(locus="region614", start=2088773, end=2088933, strand=1), + Location(locus="region615", start=2088946, end=2088949, strand=1), + Location(locus="region616", start=2089092, end=2089162, strand=1), + Location(locus="region617", start=2089292, end=2089348, strand=1), + Location(locus="region618", start=2096825, end=2096840, strand=1), + Location(locus="region619", start=2096843, end=2096849, strand=1), + Location(locus="region620", start=2102846, end=2102899, strand=1), + Location(locus="region621", start=2115708, end=2115758, strand=1), + Location(locus="region622", start=2133474, end=2133475, strand=1), + Location(locus="region623", start=2133993, end=2134046, strand=1), + Location(locus="region624", start=2134922, end=2134975, strand=1), + Location(locus="region625", start=2135424, end=2135493, strand=1), + Location(locus="region626", start=2135533, end=2135616, strand=1), + Location(locus="region627", start=2135665, end=2135748, strand=1), + Location(locus="region628", start=2146058, end=2146132, strand=1), + Location(locus="region629", start=2156798, end=2156878, strand=1), + Location(locus="region630", start=2157477, end=2157557, strand=1), + Location(locus="region631", start=2162931, end=2167311, strand=1), + Location(locus="region632", start=2167846, end=2167901, strand=1), + Location(locus="region633", start=2168808, end=2168872, strand=1), + Location(locus="region634", start=2168886, end=2168950, strand=1), + Location(locus="region635", start=2168982, end=2169056, strand=1), + Location(locus="region636", start=2169060, end=2169134, strand=1), + Location(locus="region637", start=2169571, end=2169628, strand=1), + Location(locus="region638", start=2170281, end=2170334, strand=1), + Location(locus="region639", start=2181376, end=2181412, strand=1), + Location(locus="region640", start=2193009, end=2193021, strand=1), + Location(locus="region641", start=2195906, end=2196780, strand=1), + Location(locus="region642", start=2196856, end=2197248, strand=1), + Location(locus="region643", start=2197279, end=2197365, strand=1), + Location(locus="region644", start=2198685, end=2198819, strand=1), + Location(locus="region645", start=2230720, end=2230773, strand=1), + Location(locus="region646", start=2244992, end=2245020, strand=1), + Location(locus="region647", start=2260253, end=2260309, strand=1), + Location(locus="region648", start=2260343, end=2260439, strand=1), + Location(locus="region649", start=2261440, end=2261518, strand=1), + Location(locus="region650", start=2262004, end=2263175, strand=1), + Location(locus="region651", start=2266486, end=2266487, strand=1), + Location(locus="region652", start=2266507, end=2266508, strand=1), + Location(locus="region653", start=2266516, end=2266517, strand=1), + Location(locus="region654", start=2266549, end=2266550, strand=1), + Location(locus="region655", start=2266552, end=2266553, strand=1), + Location(locus="region656", start=2266582, end=2266583, strand=1), + Location(locus="region657", start=2266597, end=2266598, strand=1), + Location(locus="region658", start=2266603, end=2266604, strand=1), + Location(locus="region659", start=2266623, end=2266624, strand=1), + Location(locus="region660", start=2268721, end=2268725, strand=1), + Location(locus="region661", start=2294815, end=2294911, strand=1), + Location(locus="region662", start=2295174, end=2295242, strand=1), + Location(locus="region663", start=2295289, end=2296015, strand=1), + Location(locus="region664", start=2296029, end=2296427, strand=1), + Location(locus="region665", start=2296959, end=2297045, strand=1), + Location(locus="region666", start=2298089, end=2298160, strand=1), + Location(locus="region667", start=2299186, end=2300128, strand=1), + Location(locus="region668", start=2300207, end=2300388, strand=1), + Location(locus="region669", start=2300446, end=2300580, strand=1), + Location(locus="region670", start=2300911, end=2301007, strand=1), + Location(locus="region671", start=2301264, end=2301332, strand=1), + Location(locus="region672", start=2301379, end=2302105, strand=1), + Location(locus="region673", start=2302112, end=2302517, strand=1), + Location(locus="region674", start=2303046, end=2303132, strand=1), + Location(locus="region675", start=2304131, end=2304202, strand=1), + Location(locus="region676", start=2305255, end=2306197, strand=1), + Location(locus="region677", start=2306276, end=2306457, strand=1), + Location(locus="region678", start=2306512, end=2306646, strand=1), + Location(locus="region679", start=2317128, end=2317129, strand=1), + Location(locus="region680", start=2317135, end=2317136, strand=1), + Location(locus="region681", start=2329858, end=2330072, strand=1), + Location(locus="region682", start=2330143, end=2330214, strand=1), + Location(locus="region683", start=2337968, end=2338102, strand=1), + Location(locus="region684", start=2338206, end=2338215, strand=1), + Location(locus="region685", start=2338216, end=2338217, strand=1), + Location(locus="region686", start=2338415, end=2338416, strand=1), + Location(locus="region687", start=2338421, end=2338422, strand=1), + Location(locus="region688", start=2338424, end=2338425, strand=1), + Location(locus="region689", start=2338427, end=2338428, strand=1), + Location(locus="region690", start=2338430, end=2338431, strand=1), + Location(locus="region691", start=2338433, end=2338434, strand=1), + Location(locus="region692", start=2338456, end=2338457, strand=1), + Location(locus="region693", start=2338676, end=2338677, strand=1), + Location(locus="region694", start=2338678, end=2338679, strand=1), + Location(locus="region695", start=2338691, end=2338692, strand=1), + Location(locus="region696", start=2338700, end=2338702, strand=1), + Location(locus="region697", start=2338703, end=2338704, strand=1), + Location(locus="region698", start=2338706, end=2338707, strand=1), + Location(locus="region699", start=2338715, end=2338716, strand=1), + Location(locus="region700", start=2338719, end=2338720, strand=1), + Location(locus="region701", start=2339363, end=2339432, strand=1), + Location(locus="region702", start=2339441, end=2339510, strand=1), + Location(locus="region703", start=2339512, end=2339573, strand=1), + Location(locus="region704", start=2339888, end=2340051, strand=1), + Location(locus="region705", start=2340561, end=2340695, strand=1), + Location(locus="region706", start=2341429, end=2341479, strand=1), + Location(locus="region707", start=2347386, end=2347620, strand=1), + Location(locus="region708", start=2356873, end=2356918, strand=1), + Location(locus="region709", start=2356927, end=2356933, strand=1), + Location(locus="region710", start=2357181, end=2357185, strand=1), + Location(locus="region711", start=2357249, end=2357268, strand=1), + Location(locus="region712", start=2357291, end=2357297, strand=1), + Location(locus="region713", start=2357314, end=2357321, strand=1), + Location(locus="region714", start=2357417, end=2357420, strand=1), + Location(locus="region715", start=2357426, end=2357607, strand=1), + Location(locus="region716", start=2357841, end=2357901, strand=1), + Location(locus="region717", start=2358659, end=2358715, strand=1), + Location(locus="region718", start=2358755, end=2358832, strand=1), + Location(locus="region719", start=2358918, end=2358991, strand=1), + Location(locus="region720", start=2358995, end=2359057, strand=1), + Location(locus="region721", start=2359163, end=2359213, strand=1), + Location(locus="region722", start=2359554, end=2359613, strand=1), + Location(locus="region723", start=2359778, end=2359852, strand=1), + Location(locus="region724", start=2359923, end=2359982, strand=1), + Location(locus="region725", start=2360650, end=2360660, strand=1), + Location(locus="region726", start=2360730, end=2360740, strand=1), + Location(locus="region727", start=2361908, end=2361909, strand=1), + Location(locus="region728", start=2363680, end=2363682, strand=1), + Location(locus="region729", start=2365407, end=2366778, strand=1), + Location(locus="region730", start=2366889, end=2366967, strand=1), + Location(locus="region731", start=2367028, end=2367060, strand=1), + Location(locus="region732", start=2372430, end=2372565, strand=1), + Location(locus="region733", start=2380217, end=2380261, strand=1), + Location(locus="region734", start=2381446, end=2381513, strand=1), + Location(locus="region735", start=2387281, end=2387659, strand=1), + Location(locus="region736", start=2401813, end=2401936, strand=1), + Location(locus="region737", start=2423328, end=2423387, strand=1), + Location(locus="region738", start=2423424, end=2423425, strand=1), + Location(locus="region739", start=2423526, end=2423687, strand=1), + Location(locus="region740", start=2423705, end=2423775, strand=1), + Location(locus="region741", start=2423789, end=2424293, strand=1), + Location(locus="region742", start=2424483, end=2424537, strand=1), + Location(locus="region743", start=2430107, end=2431481, strand=1), + Location(locus="region744", start=2439177, end=2439954, strand=1), + Location(locus="region745", start=2440279, end=2440334, strand=1), + Location(locus="region746", start=2449219, end=2449221, strand=1), + Location(locus="region747", start=2458391, end=2458471, strand=1), + Location(locus="region748", start=2461322, end=2461510, strand=1), + Location(locus="region749", start=2462528, end=2462594, strand=1), + Location(locus="region750", start=2466995, end=2467029, strand=1), + Location(locus="region751", start=2470043, end=2470086, strand=1), + Location(locus="region752", start=2482061, end=2482111, strand=1), + Location(locus="region753", start=2482418, end=2482468, strand=1), + Location(locus="region754", start=2522186, end=2522192, strand=1), + Location(locus="region755", start=2522194, end=2522219, strand=1), + Location(locus="region756", start=2523182, end=2523239, strand=1), + Location(locus="region757", start=2531886, end=2532244, strand=1), + Location(locus="region758", start=2546432, end=2546497, strand=1), + Location(locus="region759", start=2550002, end=2551378, strand=1), + Location(locus="region760", start=2554864, end=2554933, strand=1), + Location(locus="region761", start=2577285, end=2577362, strand=1), + Location(locus="region762", start=2577679, end=2577732, strand=1), + Location(locus="region763", start=2617342, end=2617407, strand=1), + Location(locus="region764", start=2625882, end=2626688, strand=1), + Location(locus="region765", start=2627503, end=2627556, strand=1), + Location(locus="region766", start=2629274, end=2629354, strand=1), + Location(locus="region767", start=2629593, end=2629672, strand=1), + Location(locus="region768", start=2630144, end=2630239, strand=1), + Location(locus="region769", start=2630868, end=2630926, strand=1), + Location(locus="region770", start=2631042, end=2631119, strand=1), + Location(locus="region771", start=2631358, end=2631437, strand=1), + Location(locus="region772", start=2631598, end=2631599, strand=1), + Location(locus="region773", start=2631619, end=2631620, strand=1), + Location(locus="region774", start=2631900, end=2631995, strand=1), + Location(locus="region775", start=2632922, end=2637037, strand=1), + Location(locus="region776", start=2637255, end=2637534, strand=1), + Location(locus="region777", start=2638349, end=2638560, strand=1), + Location(locus="region778", start=2638985, end=2639622, strand=1), + Location(locus="region779", start=2651435, end=2651440, strand=1), + Location(locus="region780", start=2651445, end=2651447, strand=1), + Location(locus="region781", start=2651843, end=2651910, strand=1), + Location(locus="region782", start=2683501, end=2683554, strand=1), + Location(locus="region783", start=2687129, end=2687257, strand=1), + Location(locus="region784", start=2693239, end=2693589, strand=1), + Location(locus="region785", start=2693609, end=2693854, strand=1), + Location(locus="region786", start=2700466, end=2700531, strand=1), + Location(locus="region787", start=2703891, end=2704019, strand=1), + Location(locus="region788", start=2704885, end=2704886, strand=1), + Location(locus="region789", start=2716308, end=2716392, strand=1), + Location(locus="region790", start=2720671, end=2721448, strand=1), + Location(locus="region791", start=2721812, end=2721867, strand=1), + Location(locus="region792", start=2724201, end=2724221, strand=1), + Location(locus="region793", start=2729618, end=2729620, strand=1), + Location(locus="region794", start=2729832, end=2729834, strand=1), + Location(locus="region795", start=2740574, end=2740601, strand=1), + Location(locus="region796", start=2751596, end=2751658, strand=1), + Location(locus="region797", start=2784601, end=2785982, strand=1), + Location(locus="region798", start=2795376, end=2795395, strand=1), + Location(locus="region799", start=2795561, end=2795578, strand=1), + Location(locus="region800", start=2795674, end=2795724, strand=1), + Location(locus="region801", start=2795854, end=2795868, strand=1), + Location(locus="region802", start=2795872, end=2796011, strand=1), + Location(locus="region803", start=2796483, end=2796488, strand=1), + Location(locus="region804", start=2796490, end=2796492, strand=1), + Location(locus="region805", start=2796747, end=2796761, strand=1), + Location(locus="region806", start=2796871, end=2796923, strand=1), + Location(locus="region807", start=2797259, end=2797355, strand=1), + Location(locus="region808", start=2801405, end=2801452, strand=1), + Location(locus="region809", start=2801456, end=2801471, strand=1), + Location(locus="region810", start=2801822, end=2802329, strand=1), + Location(locus="region811", start=2802330, end=2802331, strand=1), + Location(locus="region812", start=2802743, end=2802850, strand=1), + Location(locus="region813", start=2802853, end=2803162, strand=1), + Location(locus="region814", start=2803467, end=2803712, strand=1), + Location(locus="region815", start=2803721, end=2803725, strand=1), + Location(locus="region816", start=2803726, end=2803773, strand=1), + Location(locus="region817", start=2803777, end=2803783, strand=1), + Location(locus="region818", start=2803823, end=2803883, strand=1), + Location(locus="region819", start=2804102, end=2804164, strand=1), + Location(locus="region820", start=2804375, end=2804706, strand=1), + Location(locus="region821", start=2804720, end=2804723, strand=1), + Location(locus="region822", start=2804746, end=2804750, strand=1), + Location(locus="region823", start=2804756, end=2804823, strand=1), + Location(locus="region824", start=2804906, end=2805754, strand=1), + Location(locus="region825", start=2806110, end=2806206, strand=1), + Location(locus="region826", start=2822573, end=2822586, strand=1), + Location(locus="region827", start=2822617, end=2822669, strand=1), + Location(locus="region828", start=2828486, end=2829938, strand=1), + Location(locus="region829", start=2836272, end=2836324, strand=1), + Location(locus="region830", start=2850917, end=2850999, strand=1), + Location(locus="region831", start=2866465, end=2866759, strand=1), + Location(locus="region832", start=2866851, end=2867786, strand=1), + Location(locus="region833", start=2877243, end=2877305, strand=1), + Location(locus="region834", start=2878035, end=2878097, strand=1), + Location(locus="region835", start=2880155, end=2880261, strand=1), + Location(locus="region836", start=2883832, end=2883904, strand=1), + Location(locus="region837", start=2884038, end=2884153, strand=1), + Location(locus="region838", start=2887448, end=2887449, strand=1), + Location(locus="region839", start=2921969, end=2922026, strand=1), + Location(locus="region840", start=2922097, end=2922119, strand=1), + Location(locus="region841", start=2922181, end=2922254, strand=1), + Location(locus="region842", start=2922357, end=2922373, strand=1), + Location(locus="region843", start=2922436, end=2922459, strand=1), + Location(locus="region844", start=2922725, end=2922835, strand=1), + Location(locus="region845", start=2922867, end=2922930, strand=1), + Location(locus="region846", start=2922937, end=2922960, strand=1), + Location(locus="region847", start=2923091, end=2923143, strand=1), + Location(locus="region848", start=2935119, end=2935172, strand=1), + Location(locus="region849", start=2943754, end=2943801, strand=1), + Location(locus="region850", start=2944205, end=2945233, strand=1), + Location(locus="region851", start=2953436, end=2953513, strand=1), + Location(locus="region852", start=2960226, end=2960592, strand=1), + Location(locus="region853", start=2960877, end=2960880, strand=1), + Location(locus="region854", start=2960929, end=2961063, strand=1), + Location(locus="region855", start=2961069, end=2961071, strand=1), + Location(locus="region856", start=2961078, end=2961083, strand=1), + Location(locus="region857", start=2961085, end=2961231, strand=1), + Location(locus="region858", start=2961334, end=2961341, strand=1), + Location(locus="region859", start=2961355, end=2961356, strand=1), + Location(locus="region860", start=2961366, end=2961401, strand=1), + Location(locus="region861", start=2961409, end=2961412, strand=1), + Location(locus="region862", start=2961446, end=2961938, strand=1), + Location(locus="region863", start=2961961, end=2961962, strand=1), + Location(locus="region864", start=2971755, end=2971868, strand=1), + Location(locus="region865", start=2971940, end=2971990, strand=1), + Location(locus="region866", start=2972101, end=2973473, strand=1), + Location(locus="region867", start=2974050, end=2974162, strand=1), + Location(locus="region868", start=2974273, end=2974345, strand=1), + Location(locus="region869", start=2974410, end=2974651, strand=1), + Location(locus="region870", start=2974652, end=2974758, strand=1), + Location(locus="region871", start=2974767, end=2974912, strand=1), + Location(locus="region872", start=2974913, end=2975136, strand=1), + Location(locus="region873", start=2975263, end=2975329, strand=1), + Location(locus="region874", start=2975390, end=2975461, strand=1), + Location(locus="region875", start=2975465, end=2975697, strand=1), + Location(locus="region876", start=2975726, end=2975962, strand=1), + Location(locus="region877", start=2978905, end=2979050, strand=1), + Location(locus="region878", start=2980970, end=2980998, strand=1), + Location(locus="region879", start=2982937, end=2983859, strand=1), + Location(locus="region880", start=2989950, end=2989952, strand=1), + Location(locus="region881", start=2990578, end=2990706, strand=1), + Location(locus="region882", start=2996000, end=2996173, strand=1), + Location(locus="region883", start=3000927, end=3000997, strand=1), + Location(locus="region884", start=3001076, end=3001136, strand=1), + Location(locus="region885", start=3001304, end=3001385, strand=1), + Location(locus="region886", start=3001421, end=3001480, strand=1), + Location(locus="region887", start=3001760, end=3001811, strand=1), + Location(locus="region888", start=3002296, end=3002366, strand=1), + Location(locus="region889", start=3002445, end=3002505, strand=1), + Location(locus="region890", start=3002673, end=3002754, strand=1), + Location(locus="region891", start=3002790, end=3002849, strand=1), + Location(locus="region892", start=3003129, end=3003180, strand=1), + Location(locus="region893", start=3007032, end=3007227, strand=1), + Location(locus="region894", start=3018717, end=3018767, strand=1), + Location(locus="region895", start=3018795, end=3018854, strand=1), + Location(locus="region896", start=3022728, end=3022778, strand=1), + Location(locus="region897", start=3022806, end=3022865, strand=1), + Location(locus="region898", start=3026262, end=3026284, strand=1), + Location(locus="region899", start=3054576, end=3054577, strand=1), + Location(locus="region900", start=3054578, end=3054941, strand=1), + Location(locus="region901", start=3054952, end=3055236, strand=1), + Location(locus="region902", start=3059792, end=3059850, strand=1), + Location(locus="region903", start=3073062, end=3073136, strand=1), + Location(locus="region904", start=3076898, end=3076962, strand=1), + Location(locus="region905", start=3078168, end=3078218, strand=1), + Location(locus="region906", start=3082462, end=3082661, strand=1), + Location(locus="region907", start=3082704, end=3082763, strand=1), + Location(locus="region908", start=3097654, end=3097715, strand=1), + Location(locus="region909", start=3100170, end=3100401, strand=1), + Location(locus="region910", start=3100446, end=3100511, strand=1), + Location(locus="region911", start=3100515, end=3100571, strand=1), + Location(locus="region912", start=3100694, end=3100799, strand=1), + Location(locus="region913", start=3100879, end=3100939, strand=1), + Location(locus="region914", start=3100965, end=3101132, strand=1), + Location(locus="region915", start=3101235, end=3101377, strand=1), + Location(locus="region916", start=3101429, end=3101543, strand=1), + Location(locus="region917", start=3101660, end=3101731, strand=1), + Location(locus="region918", start=3101861, end=3101911, strand=1), + Location(locus="region919", start=3102099, end=3102229, strand=1), + Location(locus="region920", start=3102340, end=3102390, strand=1), + Location(locus="region921", start=3104976, end=3105044, strand=1), + Location(locus="region922", start=3112312, end=3112313, strand=1), + Location(locus="region923", start=3112459, end=3112460, strand=1), + Location(locus="region924", start=3113017, end=3113104, strand=1), + Location(locus="region925", start=3113775, end=3113862, strand=1), + Location(locus="region926", start=3116414, end=3116522, strand=1), + Location(locus="region927", start=3116682, end=3116766, strand=1), + Location(locus="region928", start=3116843, end=3116989, strand=1), + Location(locus="region929", start=3119560, end=3119563, strand=1), + Location(locus="region930", start=3119566, end=3122702, strand=1), + Location(locus="region931", start=3122803, end=3122918, strand=1), + Location(locus="region932", start=3122931, end=3122942, strand=1), + Location(locus="region933", start=3122948, end=3122954, strand=1), + Location(locus="region934", start=3123027, end=3123283, strand=1), + Location(locus="region935", start=3123316, end=3123353, strand=1), + Location(locus="region936", start=3123422, end=3123424, strand=1), + Location(locus="region937", start=3132887, end=3133461, strand=1), + Location(locus="region938", start=3135783, end=3136357, strand=1), + Location(locus="region939", start=3138022, end=3138085, strand=1), + Location(locus="region940", start=3147107, end=3147108, strand=1), + Location(locus="region941", start=3147110, end=3147119, strand=1), + Location(locus="region942", start=3155875, end=3156094, strand=1), + Location(locus="region943", start=3160526, end=3160587, strand=1), + Location(locus="region944", start=3162643, end=3162703, strand=1), + Location(locus="region945", start=3162806, end=3162923, strand=1), + Location(locus="region946", start=3163470, end=3163548, strand=1), + Location(locus="region947", start=3163615, end=3163617, strand=1), + Location(locus="region948", start=3163619, end=3164033, strand=1), + Location(locus="region949", start=3171459, end=3171634, strand=1), + Location(locus="region950", 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strand=1), + Location(locus="region965", start=3247233, end=3247304, strand=1), + Location(locus="region966", start=3247313, end=3247471, strand=1), + Location(locus="region967", start=3247557, end=3247739, strand=1), + Location(locus="region968", start=3247809, end=3248173, strand=1), + Location(locus="region969", start=3248283, end=3248335, strand=1), + Location(locus="region970", start=3251411, end=3251470, strand=1), + Location(locus="region971", start=3252647, end=3252718, strand=1), + Location(locus="region972", start=3252727, end=3252885, strand=1), + Location(locus="region973", start=3252971, end=3253153, strand=1), + Location(locus="region974", start=3253223, end=3253587, strand=1), + Location(locus="region975", start=3253733, end=3253738, strand=1), + Location(locus="region976", start=3257962, end=3258024, strand=1), + Location(locus="region977", start=3258181, end=3258232, strand=1), + Location(locus="region978", start=3258342, end=3258404, strand=1), + Location(locus="region979", start=3262593, end=3262652, strand=1), + Location(locus="region980", start=3266035, end=3266081, strand=1), + Location(locus="region981", start=3276956, end=3277006, strand=1), + Location(locus="region982", start=3277821, end=3277904, strand=1), + Location(locus="region983", start=3281070, end=3281123, strand=1), + Location(locus="region984", start=3281221, end=3281240, strand=1), + Location(locus="region985", start=3284730, end=3284810, strand=1), + Location(locus="region986", start=3287950, end=3288005, strand=1), + Location(locus="region987", start=3290432, end=3290482, strand=1), + Location(locus="region988", start=3291393, end=3291510, strand=1), + Location(locus="region989", start=3292983, end=3293052, strand=1), + Location(locus="region990", start=3293178, end=3293237, strand=1), + Location(locus="region991", start=3295507, end=3295562, strand=1), + Location(locus="region992", start=3296594, end=3296665, strand=1), + Location(locus="region993", start=3297173, end=3297238, strand=1), + Location(locus="region994", start=3307727, end=3307761, strand=1), + Location(locus="region995", start=3311027, end=3311090, strand=1), + Location(locus="region996", start=3311308, end=3311393, strand=1), + Location(locus="region997", start=3311534, end=3311599, strand=1), + Location(locus="region998", start=3313346, end=3313396, strand=1), + Location(locus="region999", start=3314116, end=3314179, strand=1), + Location(locus="region1000", start=3314397, end=3314482, strand=1), + Location(locus="region1001", start=3314623, end=3314688, strand=1), + Location(locus="region1002", start=3317572, end=3317743, strand=1), + Location(locus="region1003", start=3319468, end=3319665, strand=1), + Location(locus="region1004", start=3333753, end=3333984, strand=1), + Location(locus="region1005", start=3333990, end=3334184, strand=1), + Location(locus="region1006", start=3334239, end=3334370, strand=1), + Location(locus="region1007", start=3334557, end=3334609, strand=1), + Location(locus="region1008", start=3334646, end=3334739, strand=1), + Location(locus="region1009", start=3334822, end=3334960, strand=1), + Location(locus="region1010", start=3335016, end=3335084, strand=1), + Location(locus="region1011", start=3335246, end=3335317, strand=1), + Location(locus="region1012", start=3335357, end=3335410, strand=1), + Location(locus="region1013", start=3335447, end=3335497, strand=1), + Location(locus="region1014", start=3335504, end=3335566, strand=1), + Location(locus="region1015", start=3335741, end=3335815, strand=1), + Location(locus="region1016", start=3336500, end=3336803, strand=1), + Location(locus="region1017", start=3343348, end=3343447, strand=1), + Location(locus="region1018", start=3348477, end=3348544, strand=1), + Location(locus="region1019", start=3351084, end=3351220, strand=1), + Location(locus="region1020", start=3369930, end=3369931, strand=1), + Location(locus="region1021", start=3369937, end=3369942, strand=1), + Location(locus="region1022", start=3376515, end=3376543, strand=1), + Location(locus="region1023", start=3376746, end=3376809, strand=1), + Location(locus="region1024", start=3376921, end=3377368, strand=1), + Location(locus="region1025", start=3377645, end=3378276, strand=1), + Location(locus="region1026", start=3378329, end=3378443, strand=1), + Location(locus="region1027", start=3378895, end=3378960, strand=1), + Location(locus="region1028", start=3379196, end=3379285, strand=1), + Location(locus="region1029", start=3379358, end=3380715, strand=1), + Location(locus="region1030", start=3380907, end=3381021, strand=1), + Location(locus="region1031", start=3381307, end=3382755, strand=1), + Location(locus="region1032", start=3415197, end=3415211, strand=1), + Location(locus="region1033", start=3430332, end=3430388, strand=1), + Location(locus="region1034", start=3451379, end=3451439, strand=1), + Location(locus="region1035", start=3463548, end=3463559, strand=1), + Location(locus="region1036", start=3477289, end=3477404, strand=1), + Location(locus="region1037", start=3481318, end=3482769, strand=1), + Location(locus="region1038", start=3483942, end=3485117, strand=1), + Location(locus="region1039", start=3491173, end=3491238, strand=1), + Location(locus="region1040", start=3491292, end=3491383, strand=1), + Location(locus="region1041", start=3491605, end=3491662, strand=1), + Location(locus="region1042", start=3491745, end=3491860, strand=1), + Location(locus="region1043", start=3501334, end=3501335, strand=1), + Location(locus="region1044", start=3502155, end=3502265, strand=1), + Location(locus="region1045", start=3524464, end=3524527, strand=1), + Location(locus="region1046", start=3528083, end=3528084, strand=1), + Location(locus="region1047", start=3528086, end=3528087, strand=1), + Location(locus="region1048", start=3528098, end=3528099, strand=1), + Location(locus="region1049", start=3528101, end=3528102, strand=1), + Location(locus="region1050", start=3528116, end=3528117, strand=1), + Location(locus="region1051", start=3528118, end=3528120, strand=1), + Location(locus="region1052", start=3528128, end=3528129, strand=1), + Location(locus="region1053", start=3528139, end=3528140, strand=1), + Location(locus="region1054", start=3528143, end=3528144, strand=1), + Location(locus="region1055", start=3528157, end=3528159, strand=1), + Location(locus="region1056", start=3528164, end=3528165, strand=1), + Location(locus="region1057", start=3528191, end=3528192, strand=1), + Location(locus="region1058", start=3528197, end=3528198, strand=1), + Location(locus="region1059", start=3528674, end=3529181, strand=1), + Location(locus="region1060", start=3537803, end=3537820, strand=1), + Location(locus="region1061", start=3551223, end=3554075, strand=1), + Location(locus="region1062", start=3558759, end=3558794, strand=1), + Location(locus="region1063", start=3572554, end=3572610, strand=1), + Location(locus="region1064", start=3590630, end=3590687, strand=1), + Location(locus="region1065", start=3594262, end=3594465, strand=1), + Location(locus="region1066", start=3595987, end=3596005, strand=1), + Location(locus="region1067", start=3598349, end=3598405, strand=1), + Location(locus="region1068", start=3598436, end=3598532, strand=1), + Location(locus="region1069", start=3598641, end=3598719, strand=1), + Location(locus="region1070", start=3617102, end=3617103, strand=1), + Location(locus="region1071", start=3626606, end=3626667, strand=1), + Location(locus="region1072", start=3628084, end=3628147, strand=1), + Location(locus="region1073", start=3658635, end=3658712, strand=1), + Location(locus="region1074", start=3663723, end=3664000, strand=1), + Location(locus="region1075", start=3690944, end=3691077, strand=1), + Location(locus="region1076", start=3704903, end=3704991, strand=1), + Location(locus="region1077", start=3707577, end=3707634, strand=1), + Location(locus="region1078", start=3710374, end=3712827, strand=1), + Location(locus="region1079", start=3724548, end=3724618, strand=1), + Location(locus="region1080", start=3729448, end=3729597, strand=1), + Location(locus="region1081", start=3729626, end=3729676, strand=1), + Location(locus="region1082", start=3730345, end=3732799, strand=1), + Location(locus="region1083", start=3734471, end=3734529, strand=1), + Location(locus="region1084", start=3735634, end=3736288, strand=1), + Location(locus="region1085", start=3736501, end=3736555, strand=1), + Location(locus="region1086", start=3736693, end=3736747, strand=1), + Location(locus="region1087", start=3737092, end=3737207, strand=1), + Location(locus="region1088", start=3737268, end=3737497, strand=1), + Location(locus="region1089", start=3737804, end=3737808, strand=1), + Location(locus="region1090", start=3737814, end=3737818, strand=1), + Location(locus="region1091", start=3737828, end=3737836, strand=1), + Location(locus="region1092", start=3737992, end=3738961, strand=1), + Location(locus="region1093", start=3738977, end=3738985, strand=1), + Location(locus="region1094", start=3739052, end=3739056, strand=1), + Location(locus="region1095", start=3739131, end=3739133, strand=1), + Location(locus="region1096", start=3739159, end=3739163, strand=1), + Location(locus="region1097", start=3739194, end=3739202, strand=1), + Location(locus="region1098", start=3739207, end=3739899, strand=1), + Location(locus="region1099", start=3739960, end=3740010, strand=1), + Location(locus="region1100", start=3740065, end=3740131, strand=1), + Location(locus="region1101", start=3740138, end=3740140, strand=1), + Location(locus="region1102", start=3740161, end=3740208, strand=1), + Location(locus="region1103", start=3740214, end=3740229, strand=1), + Location(locus="region1104", start=3740302, end=3740322, strand=1), + Location(locus="region1105", start=3740338, end=3740574, strand=1), + Location(locus="region1106", start=3740592, end=3740604, strand=1), + Location(locus="region1107", start=3740617, end=3740620, strand=1), + Location(locus="region1108", start=3740630, end=3740632, strand=1), + Location(locus="region1109", start=3740644, end=3740655, strand=1), + Location(locus="region1110", start=3740659, end=3740666, strand=1), + Location(locus="region1111", start=3740681, end=3740698, strand=1), + Location(locus="region1112", start=3740702, end=3740939, strand=1), + Location(locus="region1113", start=3741172, end=3741178, strand=1), + Location(locus="region1114", start=3741286, end=3741394, strand=1), + Location(locus="region1115", start=3741502, end=3741604, strand=1), + Location(locus="region1116", start=3741624, end=3741678, strand=1), + Location(locus="region1117", start=3741681, end=3741914, strand=1), + Location(locus="region1118", start=3741942, end=3742247, strand=1), + Location(locus="region1119", start=3742250, end=3742256, strand=1), + Location(locus="region1120", start=3742316, end=3742371, strand=1), + Location(locus="region1121", start=3743211, end=3743502, strand=1), + Location(locus="region1122", start=3743507, end=3743603, strand=1), + Location(locus="region1123", start=3743710, end=3753184, strand=1), + Location(locus="region1124", start=3753326, end=3754368, strand=1), + Location(locus="region1125", start=3756036, end=3756185, strand=1), + Location(locus="region1126", start=3756410, end=3756480, strand=1), + Location(locus="region1127", start=3756941, end=3757478, strand=1), + Location(locus="region1128", start=3757570, end=3757629, strand=1), + Location(locus="region1129", start=3757773, end=3757828, strand=1), + Location(locus="region1130", start=3757879, end=3757971, strand=1), + Location(locus="region1131", start=3757972, end=3758040, strand=1), + Location(locus="region1132", start=3758117, end=3758193, strand=1), + Location(locus="region1133", start=3758716, end=3759099, strand=1), + Location(locus="region1134", start=3759107, end=3759186, strand=1), + Location(locus="region1135", start=3759331, end=3759390, strand=1), + Location(locus="region1136", start=3759534, end=3759589, strand=1), + Location(locus="region1137", start=3759679, end=3759738, strand=1), + Location(locus="region1138", start=3759826, end=3759909, strand=1), + Location(locus="region1139", start=3760356, end=3760409, strand=1), + Location(locus="region1140", start=3760417, end=3760675, strand=1), + Location(locus="region1141", start=3760753, end=3760985, strand=1), + Location(locus="region1142", start=3762384, end=3762655, strand=1), + Location(locus="region1143", start=3762661, end=3762818, strand=1), + Location(locus="region1144", start=3763048, end=3763101, strand=1), + Location(locus="region1145", start=3763223, end=3763275, strand=1), + Location(locus="region1146", start=3763282, end=3763332, strand=1), + Location(locus="region1147", start=3764059, end=3764114, strand=1), + Location(locus="region1148", start=3764134, end=3764237, strand=1), + Location(locus="region1149", start=3764251, end=3764523, strand=1), + Location(locus="region1150", start=3764809, end=3764862, strand=1), + Location(locus="region1151", start=3764980, end=3765076, strand=1), + Location(locus="region1152", start=3765161, end=3765219, strand=1), + Location(locus="region1153", start=3765798, end=3765987, strand=1), + Location(locus="region1154", start=3766018, end=3766179, strand=1), + Location(locus="region1155", start=3766215, end=3766396, strand=1), + Location(locus="region1156", start=3766435, end=3766518, strand=1), + Location(locus="region1157", start=3766552, end=3766722, strand=1), + Location(locus="region1158", start=3766760, end=3766819, strand=1), + Location(locus="region1159", start=3766829, end=3767099, strand=1), + Location(locus="region1160", start=3769527, end=3769724, strand=1), + Location(locus="region1161", start=3769749, end=3769854, strand=1), + Location(locus="region1162", start=3770993, end=3771089, strand=1), + Location(locus="region1163", start=3779545, end=3779766, strand=1), + Location(locus="region1164", start=3779809, end=3779899, strand=1), + Location(locus="region1165", start=3779936, end=3779981, strand=1), + Location(locus="region1166", start=3780156, end=3780175, strand=1), + Location(locus="region1167", start=3794868, end=3796422, strand=1), + Location(locus="region1168", start=3800030, end=3800120, strand=1), + Location(locus="region1169", start=3801824, end=3801874, strand=1), + Location(locus="region1170", start=3802056, end=3802113, strand=1), + Location(locus="region1171", start=3802122, end=3803827, strand=1), + Location(locus="region1172", start=3803844, end=3803919, strand=1), + Location(locus="region1173", start=3808262, end=3808421, strand=1), + Location(locus="region1174", start=3820387, end=3820598, strand=1), + Location(locus="region1175", start=3820711, end=3820772, strand=1), + Location(locus="region1176", start=3835202, end=3835264, strand=1), + Location(locus="region1177", start=3841619, end=3842454, strand=1), + Location(locus="region1178", start=3842471, end=3842551, strand=1), + Location(locus="region1179", start=3842560, end=3842670, strand=1), + Location(locus="region1180", start=3842725, end=3842907, strand=1), + Location(locus="region1181", start=3842979, end=3843117, strand=1), + Location(locus="region1182", start=3843182, end=3843275, strand=1), + Location(locus="region1183", start=3843317, end=3843468, strand=1), + Location(locus="region1184", start=3843519, end=3843520, strand=1), + Location(locus="region1185", start=3843523, end=3843705, strand=1), + Location(locus="region1186", start=3843713, end=3843714, strand=1), + Location(locus="region1187", start=3843748, end=3843749, strand=1), + Location(locus="region1188", start=3843750, end=3843753, strand=1), + Location(locus="region1189", start=3843759, end=3843760, strand=1), + Location(locus="region1190", start=3844681, end=3844756, strand=1), + Location(locus="region1191", start=3845970, end=3847246, strand=1), + Location(locus="region1192", start=3847305, end=3847404, strand=1), + Location(locus="region1193", start=3847446, end=3847581, strand=1), + Location(locus="region1194", start=3847700, end=3847711, strand=1), + Location(locus="region1195", start=3847714, end=3847896, strand=1), + Location(locus="region1196", start=3862570, end=3862575, strand=1), + Location(locus="region1197", start=3862576, end=3862578, strand=1), + Location(locus="region1198", start=3873526, end=3873540, strand=1), + Location(locus="region1199", start=3878561, end=3878637, strand=1), + Location(locus="region1200", start=3883543, end=3884926, strand=1), + Location(locus="region1201", start=3890771, end=3892143, strand=1), + Location(locus="region1202", start=3894402, end=3894790, strand=1), + Location(locus="region1203", start=3894863, end=3895078, strand=1), + Location(locus="region1204", start=3895083, end=3895137, strand=1), + Location(locus="region1205", start=3895184, end=3895525, strand=1), + Location(locus="region1206", start=3909753, end=3909823, strand=1), + Location(locus="region1207", start=3920470, end=3920549, strand=1), + Location(locus="region1208", start=3926568, end=3930714, strand=1), + Location(locus="region1209", start=3930985, end=3936710, strand=1), + Location(locus="region1210", start=3939616, end=3944963, strand=1), + Location(locus="region1211", start=3945089, end=3945604, strand=1), + Location(locus="region1212", start=3945774, end=3950263, strand=1), + Location(locus="region1213", start=3950821, end=3951336, strand=1), + Location(locus="region1214", start=3953332, end=3953403, strand=1), + Location(locus="region1215", start=3971370, end=3971455, strand=1), + Location(locus="region1216", start=3971458, end=3971524, strand=1), + Location(locus="region1217", start=3971981, end=3972034, strand=1), + Location(locus="region1218", start=3972081, end=3972195, strand=1), + Location(locus="region1219", start=3972211, end=3972290, strand=1), + Location(locus="region1220", start=3972337, end=3972393, strand=1), + Location(locus="region1221", start=3991561, end=3991619, strand=1), + Location(locus="region1222", start=3998150, end=3998204, strand=1), + Location(locus="region1223", start=3998607, end=3998613, strand=1), + Location(locus="region1224", start=3998824, end=3998942, strand=1), + Location(locus="region1225", start=3998991, end=3999071, strand=1), + Location(locus="region1226", start=4021388, end=4021460, strand=1), + Location(locus="region1227", start=4031606, end=4031660, strand=1), + Location(locus="region1228", start=4031821, end=4031838, strand=1), + Location(locus="region1229", start=4031924, end=4031943, strand=1), + Location(locus="region1230", start=4031955, end=4032014, strand=1), + Location(locus="region1231", start=4032019, end=4032024, strand=1), + Location(locus="region1232", start=4032382, end=4032639, strand=1), + Location(locus="region1233", start=4032757, end=4032820, strand=1), + Location(locus="region1234", start=4036846, end=4037194, strand=1), + Location(locus="region1235", start=4037349, end=4037350, strand=1), + Location(locus="region1236", start=4037353, end=4037354, strand=1), + Location(locus="region1237", start=4037446, end=4037497, strand=1), + Location(locus="region1238", start=4037832, end=4037883, strand=1), + Location(locus="region1239", start=4038741, end=4038794, strand=1), + Location(locus="region1240", start=4038844, end=4038845, strand=1), + Location(locus="region1241", start=4038846, end=4038882, strand=1), + Location(locus="region1242", start=4039675, end=4039747, strand=1), + Location(locus="region1243", start=4040022, end=4040104, strand=1), + Location(locus="region1244", start=4052949, end=4053603, strand=1), + Location(locus="region1245", start=4053634, end=4053852, strand=1), + Location(locus="region1246", start=4059977, end=4060595, strand=1), + Location(locus="region1247", start=4061422, end=4061526, strand=1), + Location(locus="region1248", start=4070033, end=4070083, strand=1), + Location(locus="region1249", start=4070261, end=4070347, strand=1), + Location(locus="region1250", start=4077656, end=4077706, strand=1), + Location(locus="region1251", start=4077788, end=4077860, strand=1), + Location(locus="region1252", start=4077890, end=4077961, strand=1), + Location(locus="region1253", start=4077977, end=4078205, strand=1), + Location(locus="region1254", start=4087476, end=4087626, strand=1), + Location(locus="region1255", start=4090857, end=4090910, strand=1), + Location(locus="region1256", start=4091336, end=4091423, strand=1), + Location(locus="region1257", start=4094066, end=4094346, strand=1), + Location(locus="region1258", start=4101192, end=4101256, strand=1), + Location(locus="region1259", start=4107450, end=4107526, strand=1), + Location(locus="region1260", start=4120913, end=4121197, strand=1), + Location(locus="region1261", start=4134600, end=4134730, strand=1), + Location(locus="region1262", start=4139502, end=4139566, strand=1), + Location(locus="region1263", start=4139567, end=4139569, strand=1), + Location(locus="region1264", start=4143900, end=4143956, strand=1), + Location(locus="region1265", start=4155453, end=4155589, strand=1), + Location(locus="region1266", start=4156793, end=4156975, strand=1), + Location(locus="region1267", start=4168470, end=4168482, strand=1), + Location(locus="region1268", start=4175392, end=4175410, strand=1), + Location(locus="region1269", start=4189439, end=4189509, strand=1), + Location(locus="region1270", start=4190056, end=4190144, strand=1), + Location(locus="region1271", start=4199122, end=4199189, strand=1), + Location(locus="region1272", start=4201240, end=4201294, strand=1), + Location(locus="region1273", start=4216126, end=4216272, strand=1), + Location(locus="region1274", start=4216347, end=4216431, strand=1), + Location(locus="region1275", start=4216591, end=4216699, strand=1), + Location(locus="region1276", start=4221245, end=4221301, strand=1), + Location(locus="region1277", start=4221341, end=4221418, strand=1), + Location(locus="region1278", start=4221504, end=4221577, strand=1), + Location(locus="region1279", start=4221581, end=4221643, strand=1), + Location(locus="region1280", start=4221749, end=4221799, strand=1), + Location(locus="region1281", start=4222095, end=4222154, strand=1), + Location(locus="region1282", start=4222319, end=4222393, strand=1), + Location(locus="region1283", start=4222464, end=4222523, strand=1), + Location(locus="region1284", start=4222572, end=4222639, strand=1), + Location(locus="region1285", start=4231319, end=4232393, strand=1), + Location(locus="region1286", start=4237930, end=4237998, strand=1), + Location(locus="region1287", start=4240442, end=4240492, strand=1), + Location(locus="region1288", start=4247057, end=4247107, strand=1), + Location(locus="region1289", start=4252876, end=4254339, strand=1), + Location(locus="region1290", start=4265704, end=4265757, strand=1), + Location(locus="region1291", start=4266206, end=4266275, strand=1), + Location(locus="region1292", start=4266315, end=4266398, strand=1), + Location(locus="region1293", start=4266447, end=4266530, strand=1), + Location(locus="region1294", start=4288132, end=4288218, strand=1), + Location(locus="region1295", start=4293984, end=4294056, strand=1), + Location(locus="region1296", start=4294402, end=4294459, strand=1), + Location(locus="region1297", start=4294717, end=4294773, strand=1), + Location(locus="region1298", start=4296685, end=4296735, strand=1), + Location(locus="region1299", start=4297903, end=4297956, strand=1), + Location(locus="region1300", start=4301213, end=4301287, strand=1), + Location(locus="region1301", start=4301540, end=4301806, strand=1), + Location(locus="region1302", start=4301861, end=4302004, strand=1), + Location(locus="region1303", start=4302084, end=4302144, strand=1), + Location(locus="region1304", start=4302170, end=4302248, strand=1), + Location(locus="region1305", start=4302440, end=4302523, strand=1), + Location(locus="region1306", start=4302527, end=4302577, strand=1), + Location(locus="region1307", start=4302652, end=4302715, strand=1), + Location(locus="region1308", start=4302868, end=4302924, strand=1), + Location(locus="region1309", start=4302976, end=4303029, strand=1), + Location(locus="region1310", start=4303123, end=4303185, strand=1), + Location(locus="region1311", start=4303304, end=4303433, strand=1), + Location(locus="region1312", start=4317963, end=4318064, strand=1), + Location(locus="region1313", start=4318102, end=4318154, strand=1), + Location(locus="region1314", start=4318336, end=4319378, strand=1), + Location(locus="region1315", start=4320040, end=4320112, strand=1), + Location(locus="region1316", start=4340937, end=4340993, strand=1), + Location(locus="region1317", start=4348719, end=4348834, strand=1), + Location(locus="region1318", start=4353179, end=4353460, strand=1), + Location(locus="region1319", start=4353839, end=4353891, strand=1), + Location(locus="region1320", start=4359134, end=4359135, strand=1), + Location(locus="region1321", start=4361058, end=4361100, strand=1), + Location(locus="region1322", start=4368618, end=4368637, strand=1), + Location(locus="region1323", start=4369564, end=4369624, strand=1), + Location(locus="region1324", start=4383309, end=4383359, strand=1), ] @doc_inherit diff --git a/src/tb_variant_filter/masks/mtbseq.py b/src/tb_variant_filter/masks/mtbseq.py index fbd86b6..379ac0f 100644 --- a/src/tb_variant_filter/masks/mtbseq.py +++ b/src/tb_variant_filter/masks/mtbseq.py @@ -29,27 +29,27 @@ class MTBseqRegions(RegionList): regions = [ Location(locus="Rv0005", start=5240, end=7267, strand=1), Location(locus="Rv0006", start=7302, end=9818, strand=1), - Location(locus='Rv0643c', start=737268, end=738149, strand=-1), + Location(locus="Rv0643c", start=737268, end=738149, strand=-1), Location(locus="Rv0667", start=759807, end=763325, strand=1), - Location(locus='Rv0678', start=778990, end=779487, strand=1), + Location(locus="Rv0678", start=778990, end=779487, strand=1), Location(locus="Rv0682", start=781560, end=781934, strand=1), Location(locus="Rv0701", start=800809, end=801462, strand=1), - Location(locus='Rv1173', start=1302931, end=1305501, strand=1), - Location(locus='Rv1305', start=1461045, end=1461290, strand=1), + Location(locus="Rv1173", start=1302931, end=1305501, strand=1), + Location(locus="Rv1305", start=1461045, end=1461290, strand=1), Location(locus="Rv1484", start=1674202, end=1675011, strand=1), Location(locus="Rv1630", start=1833542, end=1834987, strand=1), Location(locus="Rv1694", start=1917940, end=1918746, strand=1), - Location(locus='Rv1704c', start=1929786, end=1931456, strand=-1), + Location(locus="Rv1704c", start=1929786, end=1931456, strand=-1), Location(locus="Rv1854c", start=2101651, end=2103042, strand=-1), Location(locus="Rv1908c", start=2153889, end=2156111, strand=-1), Location(locus="Rv2043c", start=2288681, end=2289241, strand=-1), - Location(locus='Rv2447c', start=2746135, end=2747598, strand=-1), - Location(locus='Rv2670c', start=2985731, end=2986840, strand=-1), + Location(locus="Rv2447c", start=2746135, end=2747598, strand=-1), + Location(locus="Rv2670c", start=2985731, end=2986840, strand=-1), Location(locus="Rv2764c", start=3073680, end=3074471, strand=-1), - Location(locus='Rv3261', start=3640543, end=3641538, strand=1), - Location(locus='Rv3262', start=3641535, end=3642881, strand=1), - Location(locus='Rv3423c', start=3840194, end=3841420, strand=-1), - Location(locus='Rv3547', start=3986844, end=3987299, strand=1), + Location(locus="Rv3261", start=3640543, end=3641538, strand=1), + Location(locus="Rv3262", start=3641535, end=3642881, strand=1), + Location(locus="Rv3423c", start=3840194, end=3841420, strand=-1), + Location(locus="Rv3547", start=3986844, end=3987299, strand=1), Location(locus="Rv3795", start=4246514, end=4249810, strand=1), Location(locus="Rv3854c", start=4326004, end=4327473, strand=-1), Location(locus="Rv3919c", start=4407528, end=4408202, strand=-1), @@ -74,6 +74,7 @@ def load_from_web_and_db(self, bolt_url: str): graph = GraphDatabase.driver(uri=bolt_url) self.regions = RegionList.locus_list_to_locations(graph, mtbseq_ids, "id") from operator import attrgetter - for region in sorted(self.regions, key=attrgetter('start')): + + for region in sorted(self.regions, key=attrgetter("start")): print(region) graph.close() diff --git a/src/tb_variant_filter/masks/tbprofiler.py b/src/tb_variant_filter/masks/tbprofiler.py index b184347..5f4adb1 100644 --- a/src/tb_variant_filter/masks/tbprofiler.py +++ b/src/tb_variant_filter/masks/tbprofiler.py @@ -26,64 +26,65 @@ class TBProfilerRegions(RegionList): name = "TBProfiler" description = "TBProfiler resistance genes" project_url = "https://github.com/jodyphelan/TBProfiler" - regions = [ Location(locus='Rv0005', start=5040, end=7467, strand=1), - Location(locus='Rv0006', start=7102, end=10018, strand=1), - Location(locus='Rv0407', start=490583, end=491993, strand=1), - Location(locus='Rv0486', start=575148, end=576990, strand=1), - Location(locus='Rv0529', start=619691, end=621065, strand=1), - Location(locus='Rv0667', start=759607, end=763525, strand=1), - Location(locus='Rv0668', start=763170, end=767520, strand=1), - Location(locus='Rv0676c', start=775386, end=778680, strand=1), - Location(locus='Rv0677c', start=778277, end=779105, strand=1), - Location(locus='Rv0678', start=778790, end=779687, strand=1), - Location(locus='Rv0682', start=781360, end=782134, strand=1), - Location(locus='Rv0701', start=800609, end=801662, strand=1), - Location(locus='Rv1173', start=1302731, end=1305701, strand=1), - Location(locus='Rv1258c', start=1405881, end=1407540, strand=1), - Location(locus='Rv1267c', start=1415981, end=1417547, strand=1), - Location(locus='Rv1305', start=1460845, end=1461490, strand=1), - Location(locus='rrs', start=1471646, end=1473582, strand=1), - Location(locus='rrl', start=1473458, end=1476995, strand=1), - Location(locus='Rv1483', start=1673148, end=1674383, strand=1), - Location(locus='Rv1484', start=1673848, end=1675211, strand=1), - Location(locus='Rv1630', start=1833342, end=1835187, strand=1), - Location(locus='Rv1694', start=1917740, end=1918946, strand=1), - Location(locus='Rv1854c', start=2101451, end=2103242, strand=1), - Location(locus='Rv1908c', start=2153689, end=2156570, strand=1), - Location(locus='Rv1918c', start=2167449, end=2170812, strand=1), - Location(locus='Rv1979c', start=2221519, end=2223364, strand=1), - Location(locus='Rv2043c', start=2288481, end=2290323, strand=1), - Location(locus='Rv2245', start=2517915, end=2519565, strand=1), - Location(locus='Rv2416c', start=2713924, end=2715586, strand=1), - Location(locus='Rv2428', start=2725912, end=2726980, strand=1), - Location(locus='Rv2447c', start=2745935, end=2747798, strand=1), - Location(locus='Rv2535c', start=2859100, end=2860618, strand=1), - Location(locus='Rv2671', start=2986639, end=2987815, strand=1), - Location(locus='Rv2752c', start=3064315, end=3066391, strand=1), - Location(locus='Rv2754c', start=3066993, end=3068161, strand=1), - Location(locus='Rv2764c', start=3073480, end=3074671, strand=1), - Location(locus='Rv2780', start=3086620, end=3088135, strand=1), - Location(locus='Rv2983', start=3338918, end=3339962, strand=1), - Location(locus='Rv3083', start=3448304, end=3450191, strand=1), - Location(locus='Rv3106', start=3473807, end=3475577, strand=1), - Location(locus='Rv3197A', start=3568201, end=3568879, strand=1), - Location(locus='Rv3236c', start=3611759, end=3613316, strand=1), - Location(locus='Rv3261', start=3640343, end=3641738, strand=1), - Location(locus='Rv3262', start=3641335, end=3643081, strand=1), - Location(locus='Rv3423c', start=3839994, end=3841620, strand=1), - Location(locus='Rv3457c', start=3877264, end=3878707, strand=1), - Location(locus='Rv3547', start=3986644, end=3987499, strand=1), - Location(locus='Rv3596c', start=4037958, end=4040904, strand=1), - Location(locus='Rv3601c', start=4043662, end=4044481, strand=1), - Location(locus='Rv3793', start=4239663, end=4243347, strand=1), - Location(locus='Rv3794', start=4243004, end=4246717, strand=1), - Location(locus='Rv3795', start=4246314, end=4250010, strand=1), - Location(locus='Rv3805c', start=4266753, end=4269036, strand=1), - Location(locus='Rv3806c', start=4268725, end=4270033, strand=1), - Location(locus='Rv3854c', start=4325804, end=4330174, strand=1), - Location(locus='Rv3855', start=4327349, end=4328399, strand=1), - Location(locus='Rv3862c', start=4337971, end=4338721, strand=1), - Location(locus='Rv3919c', start=4407328, end=4408476, strand=1) + regions = [ + Location(locus="Rv0005", start=5040, end=7467, strand=1), + Location(locus="Rv0006", start=7102, end=10018, strand=1), + Location(locus="Rv0407", start=490583, end=491993, strand=1), + Location(locus="Rv0486", start=575148, end=576990, strand=1), + Location(locus="Rv0529", start=619691, end=621065, strand=1), + Location(locus="Rv0667", start=759607, end=763525, strand=1), + Location(locus="Rv0668", start=763170, end=767520, strand=1), + Location(locus="Rv0676c", start=775386, end=778680, strand=1), + Location(locus="Rv0677c", start=778277, end=779105, strand=1), + Location(locus="Rv0678", start=778790, end=779687, strand=1), + Location(locus="Rv0682", start=781360, end=782134, strand=1), + Location(locus="Rv0701", start=800609, end=801662, strand=1), + Location(locus="Rv1173", start=1302731, end=1305701, strand=1), + Location(locus="Rv1258c", start=1405881, end=1407540, strand=1), + Location(locus="Rv1267c", start=1415981, end=1417547, strand=1), + Location(locus="Rv1305", start=1460845, end=1461490, strand=1), + Location(locus="rrs", start=1471646, end=1473582, strand=1), + Location(locus="rrl", start=1473458, end=1476995, strand=1), + Location(locus="Rv1483", start=1673148, end=1674383, strand=1), + Location(locus="Rv1484", start=1673848, end=1675211, strand=1), + Location(locus="Rv1630", start=1833342, end=1835187, strand=1), + Location(locus="Rv1694", start=1917740, end=1918946, strand=1), + Location(locus="Rv1854c", start=2101451, end=2103242, strand=1), + Location(locus="Rv1908c", start=2153689, end=2156570, strand=1), + Location(locus="Rv1918c", start=2167449, end=2170812, strand=1), + Location(locus="Rv1979c", start=2221519, end=2223364, strand=1), + Location(locus="Rv2043c", start=2288481, end=2290323, strand=1), + Location(locus="Rv2245", start=2517915, end=2519565, strand=1), + Location(locus="Rv2416c", start=2713924, end=2715586, strand=1), + Location(locus="Rv2428", start=2725912, end=2726980, strand=1), + Location(locus="Rv2447c", start=2745935, end=2747798, strand=1), + Location(locus="Rv2535c", start=2859100, end=2860618, strand=1), + Location(locus="Rv2671", start=2986639, end=2987815, strand=1), + Location(locus="Rv2752c", start=3064315, end=3066391, strand=1), + Location(locus="Rv2754c", start=3066993, end=3068161, strand=1), + Location(locus="Rv2764c", start=3073480, end=3074671, strand=1), + Location(locus="Rv2780", start=3086620, end=3088135, strand=1), + Location(locus="Rv2983", start=3338918, end=3339962, strand=1), + Location(locus="Rv3083", start=3448304, end=3450191, strand=1), + Location(locus="Rv3106", start=3473807, end=3475577, strand=1), + Location(locus="Rv3197A", start=3568201, end=3568879, strand=1), + Location(locus="Rv3236c", start=3611759, end=3613316, strand=1), + Location(locus="Rv3261", start=3640343, end=3641738, strand=1), + Location(locus="Rv3262", start=3641335, end=3643081, strand=1), + Location(locus="Rv3423c", start=3839994, end=3841620, strand=1), + Location(locus="Rv3457c", start=3877264, end=3878707, strand=1), + Location(locus="Rv3547", start=3986644, end=3987499, strand=1), + Location(locus="Rv3596c", start=4037958, end=4040904, strand=1), + Location(locus="Rv3601c", start=4043662, end=4044481, strand=1), + Location(locus="Rv3793", start=4239663, end=4243347, strand=1), + Location(locus="Rv3794", start=4243004, end=4246717, strand=1), + Location(locus="Rv3795", start=4246314, end=4250010, strand=1), + Location(locus="Rv3805c", start=4266753, end=4269036, strand=1), + Location(locus="Rv3806c", start=4268725, end=4270033, strand=1), + Location(locus="Rv3854c", start=4325804, end=4330174, strand=1), + Location(locus="Rv3855", start=4327349, end=4328399, strand=1), + Location(locus="Rv3862c", start=4337971, end=4338721, strand=1), + Location(locus="Rv3919c", start=4407328, end=4408476, strand=1), ] @doc_inherit @@ -93,8 +94,17 @@ def load_from_web_and_db(self, bolt_url: str): data = pd.read_csv( StringIO(response.text), delimiter="\t", - names=["Chromosome", "start", "end", "locus", "name", "resistance"], + names=[ + "Chromosome", + "start", + "end", + "locus", + "name", + "resistance", + ], ) graph = GraphDatabase.driver(uri=bolt_url) - self.regions = RegionList.locus_list_to_locations(graph, data, "locus", "name") + self.regions = RegionList.locus_list_to_locations( + graph, data, "locus", "name" + ) graph.close() diff --git a/src/tb_variant_filter/masks/uvp.py b/src/tb_variant_filter/masks/uvp.py index a38b7e1..3f24632 100644 --- a/src/tb_variant_filter/masks/uvp.py +++ b/src/tb_variant_filter/masks/uvp.py @@ -264,7 +264,7 @@ def load_from_web_and_db(self, bolt_url: str): graph, uvp_df_loci_df, "locus tag" ) graph.close() - + # add the intergenic regions for i, row in uvp_df[uvp_df["Comment"].isna()].iterrows(): self.regions.append( diff --git a/src/tb_variant_filter/region_list.py b/src/tb_variant_filter/region_list.py index 270531f..5dac892 100644 --- a/src/tb_variant_filter/region_list.py +++ b/src/tb_variant_filter/region_list.py @@ -88,14 +88,21 @@ def __eq__(self, other): @staticmethod def _find_locus_by_name(tx, name): - result = tx.run("MATCH (locus) -[:LOCATED_AT]-> (location:Location) " - "WHERE ((locus:Gene or locus:PseudoGene) and locus.uniquename = $name) " - " or (locus:RRna and locus.name = $name) RETURN locus, location", name=name) + result = tx.run( + "MATCH (locus) -[:LOCATED_AT]-> (location:Location) " + "WHERE ((locus:Gene or locus:PseudoGene) and locus.uniquename = $name) " + " or (locus:RRna and locus.name = $name) RETURN locus, location", + name=name, + ) return result.single() @classmethod def locus_list_to_locations( - cls, graph: Driver, locus_df: pd.DataFrame, column_name: str, rrna_column_name: str = None + cls, + graph: Driver, + locus_df: pd.DataFrame, + column_name: str, + rrna_column_name: str = None, ): """locus_list_to_locations - lookup H37Rv coordinates of a list of gene/pseudogene/rrnas graph - neo4j Driver object (from GraphDatabase.driver()) @@ -103,11 +110,10 @@ def locus_list_to_locations( column_name - name of column in locus_df to use for locus name """ with graph.session() as session: - locations = [] for _, row in locus_df.iterrows(): locus = row[column_name] - if not locus.startswith('Rv') and rrna_column_name is not None: + if not locus.startswith("Rv") and rrna_column_name is not None: locus = row[rrna_column_name] result = session.execute_read(RegionList._find_locus_by_name, locus) if result is not None: @@ -120,7 +126,11 @@ def locus_list_to_locations( ) ) else: - print("Failed to look up coordinates for", locus, file=sys.stderr) + print( + "Failed to look up coordinates for", + locus, + file=sys.stderr, + ) return locations def to_dict(self): @@ -132,7 +142,7 @@ def to_dict(self): (k, getattr(self, k)) for k in self.__class__.__dict__.keys() if not k.startswith("_") - and not isinstance(getattr(self, k), types.FunctionType) + and not isinstance(getattr(self, k), types.FunctionType) # noqa: W503 ] ) self_to_dict["regions"] = [loc.to_dict() for loc in self.regions] diff --git a/src/tb_variant_filter/regions_to_bed.py b/src/tb_variant_filter/regions_to_bed.py index 79e3f40..5a1a1d8 100644 --- a/src/tb_variant_filter/regions_to_bed.py +++ b/src/tb_variant_filter/regions_to_bed.py @@ -26,10 +26,14 @@ def main(): region_list_names = REGIONS.keys() parser = argparse.ArgumentParser(description="Output region filter in BED format") parser.add_argument( - "--chromosome_name", help="Chromosome name to use in BED", default="NC_000962.3" + "--chromosome_name", + help="Chromosome name to use in BED", + default="NC_000962.3", ) parser.add_argument( - "region_list_name", help="Name of region list", choices=region_list_names + "region_list_name", + help="Name of region list", + choices=region_list_names, ) parser.add_argument( "output_file", diff --git a/src/tests/test_farhat_rlc.py b/src/tests/test_farhat_rlc.py index 6a24b6b..2ac081a 100644 --- a/src/tests/test_farhat_rlc.py +++ b/src/tests/test_farhat_rlc.py @@ -1,6 +1,8 @@ from tb_variant_filter.masks.farhat_rlc import FarhatLab_RLC_Regions expected = 773 + + def test_farhat_rlc_region_count(): farhat_rlc = FarhatLab_RLC_Regions() assert ( diff --git a/src/tests/test_farhat_rlc_lowmap.py b/src/tests/test_farhat_rlc_lowmap.py index 544c374..9dfdcbc 100644 --- a/src/tests/test_farhat_rlc_lowmap.py +++ b/src/tests/test_farhat_rlc_lowmap.py @@ -1,6 +1,10 @@ -from tb_variant_filter.masks.farhat_rlc_lowmap import FarhatLab_RLC_LowMap_Regions +from tb_variant_filter.masks.farhat_rlc_lowmap import ( + FarhatLab_RLC_LowMap_Regions, +) expected = 1324 + + def test_farhat_rlc_region_count(): farhat_rlc_lowmap = FarhatLab_RLC_LowMap_Regions assert ( diff --git a/src/tests/test_uvp.py b/src/tests/test_uvp.py index 696a0c3..095bec8 100644 --- a/src/tests/test_uvp.py +++ b/src/tests/test_uvp.py @@ -4,6 +4,8 @@ from .utils import skip_if_no_bolt, get_bolt_url expected = 220 + + def test_uvp_region_count(): uvp = UVPRegions() assert (