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Patch clamp data

mergedpatchclampdata-20160514.csv contains patch clamp data from Crumb et al. 2016. Note that some of the data have been updated since publication of this article.

The R script process_patchclamp_data.R processes the Crumb et al. 2016 data into correct format for simulations. This script also replaces the Crumb et al. 2016 hERG data with data from White Oak (WO_hERG_block.csv), extracted from here.

References

  • Crumb, W.J., Jr., Vicente, J., Johannesen, L., and Strauss, D.G. (2016). An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel. J Pharmacol Toxicol Methods 81, 251-262. doi: 10.1016/j.vascn.2016.03.009.