diff --git a/Dockerfile b/Dockerfile
index a5d8fe6..da2a54e 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -1,7 +1,7 @@
 # Python version can be changed, e.g.
 # FROM python:3.8
-# FROM docker.io/fnndsc/conda:python3.10.2-cuda11.6.0
-FROM docker.io/python:3.11.3-slim-bullseye
+# FROM ghcr.io/mamba-org/micromamba:1.5.1-focal-cuda-11.3.1
+FROM docker.io/python:3.12.0-slim-bookworm
 
 LABEL org.opencontainers.image.authors="FNNDSC <dev@babyMRI.org>" \
       org.opencontainers.image.title="ChRIS Plugin Title" \
@@ -11,7 +11,7 @@ ARG SRCDIR=/usr/local/src/app
 WORKDIR ${SRCDIR}
 
 COPY requirements.txt .
-RUN pip install -r requirements.txt
+RUN --mount=type=cache,target=/root/.cache/pip pip install -r requirements.txt
 
 COPY . .
 ARG extras_require=none