diff --git a/core/src/main/kotlin/org/jetbrains/kotlinx/dataframe/api/DataColumnType.kt b/core/src/main/kotlin/org/jetbrains/kotlinx/dataframe/api/DataColumnType.kt
index 2c7887ab3..91cd02eb4 100644
--- a/core/src/main/kotlin/org/jetbrains/kotlinx/dataframe/api/DataColumnType.kt
+++ b/core/src/main/kotlin/org/jetbrains/kotlinx/dataframe/api/DataColumnType.kt
@@ -11,6 +11,8 @@ import org.jetbrains.kotlinx.dataframe.impl.isNothing
 import org.jetbrains.kotlinx.dataframe.impl.projectTo
 import org.jetbrains.kotlinx.dataframe.type
 import org.jetbrains.kotlinx.dataframe.typeClass
+import java.math.BigDecimal
+import java.math.BigInteger
 import kotlin.contracts.ExperimentalContracts
 import kotlin.contracts.contract
 import kotlin.reflect.KClass
@@ -44,6 +46,8 @@ public inline fun <reified T> AnyCol.isType(): Boolean = type() == typeOf<T>()
 
 public fun AnyCol.isNumber(): Boolean = isSubtypeOf<Number?>()
 
+public fun AnyCol.isBigNumber(): Boolean = isSubtypeOf<BigInteger?>() || isSubtypeOf<BigDecimal?>()
+
 public fun AnyCol.isList(): Boolean = typeClass == List::class
 
 /**
diff --git a/core/src/main/kotlin/org/jetbrains/kotlinx/dataframe/impl/TypeUtils.kt b/core/src/main/kotlin/org/jetbrains/kotlinx/dataframe/impl/TypeUtils.kt
index 199568630..54c12362c 100644
--- a/core/src/main/kotlin/org/jetbrains/kotlinx/dataframe/impl/TypeUtils.kt
+++ b/core/src/main/kotlin/org/jetbrains/kotlinx/dataframe/impl/TypeUtils.kt
@@ -11,6 +11,8 @@ import org.jetbrains.kotlinx.dataframe.DataRow
 import org.jetbrains.kotlinx.dataframe.api.Infer
 import org.jetbrains.kotlinx.dataframe.impl.columns.createColumnGuessingType
 import org.jetbrains.kotlinx.dataframe.util.GUESS_VALUE_TYPE
+import java.math.BigDecimal
+import java.math.BigInteger
 import kotlin.reflect.KClass
 import kotlin.reflect.KType
 import kotlin.reflect.KTypeParameter
@@ -29,6 +31,7 @@ import kotlin.reflect.full.superclasses
 import kotlin.reflect.full.withNullability
 import kotlin.reflect.jvm.jvmErasure
 import kotlin.reflect.typeOf
+import kotlin.toBigDecimal as toBigDecimalKotlin
 
 internal inline fun <reified T> KClass<*>.createTypeUsing() = typeOf<T>().projectTo(this)
 
@@ -646,3 +649,18 @@ internal fun Any.asArrayAsListOrNull(): List<*>? =
         is Array<*> -> asList()
         else -> null
     }
+
+internal fun Any.isBigNumber(): Boolean = this is BigInteger || this is BigDecimal
+
+internal fun Number.toBigDecimal(): BigDecimal =
+    when (this) {
+        is BigDecimal -> this
+        is BigInteger -> this.toBigDecimalKotlin()
+        is Int -> this.toBigDecimalKotlin()
+        is Byte -> this.toInt().toBigDecimalKotlin()
+        is Short -> this.toInt().toBigDecimalKotlin()
+        is Long -> this.toBigDecimalKotlin()
+        is Float -> this.toBigDecimalKotlin()
+        is Double -> this.toBigDecimalKotlin()
+        else -> BigDecimal(this.toString())
+    }
diff --git a/core/src/main/kotlin/org/jetbrains/kotlinx/dataframe/impl/api/describe.kt b/core/src/main/kotlin/org/jetbrains/kotlinx/dataframe/impl/api/describe.kt
index dad18f490..946ddc8a2 100644
--- a/core/src/main/kotlin/org/jetbrains/kotlinx/dataframe/impl/api/describe.kt
+++ b/core/src/main/kotlin/org/jetbrains/kotlinx/dataframe/impl/api/describe.kt
@@ -5,13 +5,16 @@ import org.jetbrains.kotlinx.dataframe.DataFrame
 import org.jetbrains.kotlinx.dataframe.api.ColumnDescription
 import org.jetbrains.kotlinx.dataframe.api.add
 import org.jetbrains.kotlinx.dataframe.api.after
+import org.jetbrains.kotlinx.dataframe.api.any
 import org.jetbrains.kotlinx.dataframe.api.asColumnGroup
 import org.jetbrains.kotlinx.dataframe.api.asComparable
 import org.jetbrains.kotlinx.dataframe.api.asNumbers
 import org.jetbrains.kotlinx.dataframe.api.cast
 import org.jetbrains.kotlinx.dataframe.api.concat
+import org.jetbrains.kotlinx.dataframe.api.isBigNumber
 import org.jetbrains.kotlinx.dataframe.api.isComparable
 import org.jetbrains.kotlinx.dataframe.api.isNumber
+import org.jetbrains.kotlinx.dataframe.api.map
 import org.jetbrains.kotlinx.dataframe.api.maxOrNull
 import org.jetbrains.kotlinx.dataframe.api.mean
 import org.jetbrains.kotlinx.dataframe.api.medianOrNull
@@ -25,7 +28,9 @@ import org.jetbrains.kotlinx.dataframe.columns.size
 import org.jetbrains.kotlinx.dataframe.columns.values
 import org.jetbrains.kotlinx.dataframe.impl.columns.addPath
 import org.jetbrains.kotlinx.dataframe.impl.columns.asAnyFrameColumn
+import org.jetbrains.kotlinx.dataframe.impl.isBigNumber
 import org.jetbrains.kotlinx.dataframe.impl.renderType
+import org.jetbrains.kotlinx.dataframe.impl.toBigDecimal
 import org.jetbrains.kotlinx.dataframe.index
 import org.jetbrains.kotlinx.dataframe.kind
 import org.jetbrains.kotlinx.dataframe.type
@@ -78,12 +83,54 @@ internal fun describeImpl(cols: List<AnyCol>): DataFrame<ColumnDescription> {
             ColumnDescription::mean from { if (it.isNumber()) it.asNumbers().mean() else null }
             ColumnDescription::std from { if (it.isNumber()) it.asNumbers().std() else null }
         }
-        if (hasComparable) {
-            ColumnDescription::min from inferType { if (it.isComparable()) it.asComparable().minOrNull() else null }
+        if (hasComparable || hasNumeric) {
+            ColumnDescription::min from inferType {
+                when {
+                    it.isComparable() ->
+                        it.asComparable().minOrNull()
+
+                    // Found incomparable number types, convert all to Double or BigDecimal first
+                    it.isNumber() ->
+                        if (it.any { it?.isBigNumber() == true }) {
+                            it.map { (it as Number?)?.toBigDecimal() }.minOrNull()
+                        } else {
+                            it.map { (it as Number?)?.toDouble() }.minOrNull()
+                        }
+
+                    else -> null
+                }
+            }
             ColumnDescription::median from inferType {
-                if (it.isComparable()) it.asComparable().medianOrNull() else null
+                when {
+                    it.isComparable() ->
+                        it.asComparable().medianOrNull()
+
+                    // Found incomparable number types, convert all to Double or BigDecimal first
+                    it.isNumber() ->
+                        if (it.any { it?.isBigNumber() == true }) {
+                            it.map { (it as Number?)?.toBigDecimal() }.medianOrNull()
+                        } else {
+                            it.map { (it as Number?)?.toDouble() }.medianOrNull()
+                        }
+
+                    else -> null
+                }
+            }
+            ColumnDescription::max from inferType {
+                when {
+                    it.isComparable() -> it.asComparable().maxOrNull()
+
+                    // Found incomparable number types, convert all to Double or BigDecimal first
+                    it.isNumber() ->
+                        if (it.any { it?.isBigNumber() == true }) {
+                            it.map { (it as Number?)?.toBigDecimal() }.maxOrNull()
+                        } else {
+                            it.map { (it as Number?)?.toDouble() }.maxOrNull()
+                        }
+
+                    else -> null
+                }
             }
-            ColumnDescription::max from inferType { if (it.isComparable()) it.asComparable().maxOrNull() else null }
         }
     }
     df = df.add(ColumnDescription::freq) {
diff --git a/core/src/test/kotlin/org/jetbrains/kotlinx/dataframe/api/describe.kt b/core/src/test/kotlin/org/jetbrains/kotlinx/dataframe/api/describe.kt
index a418e8744..6f6366a60 100644
--- a/core/src/test/kotlin/org/jetbrains/kotlinx/dataframe/api/describe.kt
+++ b/core/src/test/kotlin/org/jetbrains/kotlinx/dataframe/api/describe.kt
@@ -1,7 +1,9 @@
 package org.jetbrains.kotlinx.dataframe.api
 
 import io.kotest.matchers.shouldBe
+import org.jetbrains.kotlinx.dataframe.alsoDebug
 import org.junit.Test
+import kotlin.reflect.typeOf
 
 class DescribeTests {
 
@@ -11,4 +13,60 @@ class DescribeTests {
         val df = dataFrameOf(a).drop(1)
         df.describe()["min"][0] shouldBe null
     }
+
+    @Test
+    fun `describe nullable Number column`() {
+        val a by columnOf(
+            1,
+            2.0,
+            3f,
+            4L,
+            5.toShort(),
+            6.toByte(),
+            7.toBigInteger(),
+            8.toBigDecimal(),
+            null,
+        )
+        val df = dataFrameOf(a)
+        val describe = df.describe()
+            .alsoDebug()
+            .single()
+        with(describe) {
+            name shouldBe "a"
+            type shouldBe "Number?"
+            count shouldBe 9
+            unique shouldBe 9
+            nulls shouldBe 1
+            top shouldBe 1
+            freq shouldBe 1
+            mean shouldBe 4.5
+            std shouldBe 2.449489742783178
+            min shouldBe 1.toBigDecimal()
+            median shouldBe 4.toBigDecimal()
+            max shouldBe 8.toBigDecimal()
+        }
+    }
+
+    @Test
+    fun `describe with NaNs`() {
+        val a by columnOf(1.0, 2.0, Double.NaN, 4.0)
+        val df = dataFrameOf(a)
+        val describe = df.describe()
+            .alsoDebug()
+            .single()
+        with(describe) {
+            name shouldBe "a"
+            type shouldBe "Double"
+            count shouldBe 4
+            unique shouldBe 4
+            nulls shouldBe 0
+            top shouldBe 1
+            freq shouldBe 1
+            mean.isNaN() shouldBe true
+            std.isNaN() shouldBe true
+            min shouldBe 1.0 // TODO should be NaN too?
+            median shouldBe 3.0
+            max.isNaN shouldBe true
+        }
+    }
 }