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How to get P-value by sclink_cor() function #1
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Hi, sclink_cor currently does not provide p values of the robust correlation measures, but you consider running a permutation test to get the p values. The main difference is that scLink uses a mixture model to determine which gene expression values are accurately measured and used to calculate the correlation, while cor(use= "pairwise.complete.obs") use all non-NA values. |
Thanks! |
Could you kindly provide a helper script to calculate these P-values using the bootstrapping approach you kindly highlighted in the supplementary section of your manuscript? @Vivianstats Thank you very much ! |
Hi @ismailelshimy, The permutation approach is described on page 2 of the supplementary methods (https://ars.els-cdn.com/content/image/1-s2.0-S1672022921001455-mmc1.pdf) |
hello, I like the algorithm of sclink_cor() function. But I have two questions:
1.how to get p-value of sclink_cor() result?
2. what's the difference between sclink_cor() and cor(use= "pairwise.complete.obs")
thanks!
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