diff --git a/3.evaluate_model/jump_phenotype_profiles/jump_compare_cell_types_and_time_across_phenotypes.tsv.gz b/3.evaluate_model/jump_phenotype_profiles/jump_compare_cell_types_and_time_across_phenotypes.tsv.gz index 6c17733..41d369a 100644 Binary files a/3.evaluate_model/jump_phenotype_profiles/jump_compare_cell_types_and_time_across_phenotypes.tsv.gz and b/3.evaluate_model/jump_phenotype_profiles/jump_compare_cell_types_and_time_across_phenotypes.tsv.gz differ diff --git a/3.evaluate_model/jump_phenotype_profiles/jump_most_significant_phenotype_enrichment.tsv b/3.evaluate_model/jump_phenotype_profiles/jump_most_significant_phenotype_enrichment.tsv index 5b91cf0..1803684 100644 --- a/3.evaluate_model/jump_phenotype_profiles/jump_most_significant_phenotype_enrichment.tsv +++ b/3.evaluate_model/jump_phenotype_profiles/jump_most_significant_phenotype_enrichment.tsv @@ -9,6 +9,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5124936732464903 3.526834346798202e-47 BR00116994 CYT-997 final compound C09 A549 24 388 ADCCM 0.4791916347075743 6.461081448917797e-47 BR00116991 colchicine final compound K17 A549 24 447 ADCCM 0.4267399267399267 5.571355595912257e-45 BR00116994 briciclib final compound H01 A549 24 546 ADCCM +0.4451681283511368 3.5908206971639504e-44 BR00116992 briciclib final compound H01 A549 24 490 ADCCM +0.4795180722891566 1.4462557323286564e-43 BR00116994 colchicine final compound K17 A549 24 415 ADCCM +0.4459960026648901 3.2643973260100157e-43 BR00116992 oxibendazole final compound M19 A549 24 475 ADCCM +0.4678222125624864 6.463662511478908e-43 BR00116991 oxibendazole final compound M19 A549 24 428 ADCCM +0.367932873976556 1.7952133483790945e-42 BR00116992 fludarabine-phosphate final compound N12 A549 24 697 ADCCM +0.4568764568764569 9.577255303787248e-41 BR00116992 colchicine final compound K17 A549 24 429 ADCCM +0.41643219584926533 2.3178052054413348e-39 BR00116991 briciclib final compound H01 A549 24 498 ADCCM +0.5091878472151564 8.541561285640428e-38 BR00116991 romidepsin final compound N19 A549 24 314 ADCCM +0.41726274545537384 4.6449112561952e-37 BR00116993 briciclib final compound H01 A549 24 467 ADCCM +0.43214205893934715 8.626778918788515e-37 BR00116991 KG-5 final compound C13 A549 24 433 ADCCM +0.4312799579767559 4.001000320578454e-36 BR00116994 KG-5 final compound C13 A549 24 427 ADCCM +0.3093448870990939 5.39756045947274e-35 BR00116994 fludarabine-phosphate final compound N12 A549 24 816 ADCCM +0.4074607944407926 8.07505288040855e-35 BR00116991 ixabepilone final compound J21 A549 24 463 ADCCM +0.32419496578996926 9.71024969013009e-34 BR00116994 ganetespib final compound M10 A549 24 712 ADCCM +0.400856125028729 1.730056580604237e-33 BR00116994 oxibendazole final compound M19 A549 24 458 ADCCM +0.30720601237842615 4.501080645899237e-33 BR00116994 geldanamycin final compound L01 A549 24 780 ADCCM +0.42781466938042667 5.650308069582432e-32 BR00116993 ixabepilone final compound J21 A549 24 383 ADCCM +0.30673245209009437 6.495246861511555e-32 BR00116994 AZ191 final compound I18 A549 24 755 ADCCM +0.36370941477988755 1.0547863886910607e-31 BR00116992 ixabepilone final compound J21 A549 24 531 ADCCM +0.3920704845814978 1.5843753562559395e-31 BR00116993 KG-5 final compound C13 A549 24 454 ADCCM +0.38623563813865674 1.6668072605614936e-31 BR00116993 oxibendazole final compound M19 A549 24 465 ADCCM +0.30430629041740154 2.150121432117082e-30 BR00116992 ganetespib final compound I17 A549 24 729 ADCCM +0.39370562826105554 2.185928335653872e-30 BR00116992 KG-5 final compound C13 A549 24 432 ADCCM +0.31396498118147603 5.26237225444883e-30 BR00116994 ganetespib final compound I17 A549 24 679 ADCCM +0.4258241758241758 5.543771097206915e-30 BR00116994 romidepsin final compound N19 A549 24 364 ADCCM +0.4548017771701982 3.630253474085914e-29 BR00116993 romidepsin final compound N19 A549 24 304 ADCCM +0.3728448275862069 4.290563571251434e-29 BR00116994 ixabepilone final compound J21 A549 24 464 ADCCM +0.387409200968523 4.999930298518146e-28 BR00116992 TG-101348 final compound M20 A549 24 413 ADCCM +0.3044945875759658 5.724817340557492e-28 BR00116991 NVP-HSP990 final compound E23 A549 24 668 ADCCM +0.19827927190380581 3.788840234473399e-27 BR00116991 BQ-788 final compound E08 A549 24 1546 ADCCM +0.38761966927763275 2.2031576883145606e-26 BR00116994 TG-101348 final compound M20 A549 24 384 ADCCM +0.3190758453455476 3.678683292307613e-26 BR00116991 ganetespib final compound I17 A549 24 571 ADCCM +0.3870802429379705 5.0340277228835966e-26 BR00116993 colchicine final compound K17 A549 24 381 ADCCM +0.3278674658495419 6.932311288499367e-25 BR00116994 NVP-HSP990 final compound E23 A549 24 511 ADCCM +0.2738863878687359 7.861729004129353e-25 BR00116991 geldanamycin final compound L01 A549 24 736 ADCCM +0.33240607355157054 1.7747753369131303e-24 BR00116994 buparlisib final compound D11 A549 24 491 ADCCM +0.27480438184663536 4.4870568301662876e-24 BR00116992 AZ191 final compound I18 A549 24 710 ADCCM +0.26828392320752253 5.5937847527058094e-24 BR00116992 geldanamycin final compound L01 A549 24 741 ADCCM +0.28226646248085757 2.0711998799876285e-23 BR00116993 ganetespib final compound I17 A549 24 650 ADCCM +0.29441624365482233 5.487527286920249e-23 BR00116992 BI-2536 final compound I14 A549 24 591 ADCCM +0.2953575961878602 6.810356646660492e-23 BR00116991 buparlisib final compound L12 A549 24 581 ADCCM +0.38451366441375256 2.9903706860253773e-22 BR00116991 TG-101348 final compound M20 A549 24 328 ADCCM +0.29981718464351004 4.317064376047014e-22 BR00116992 buparlisib final compound L12 A549 24 547 ADCCM +0.249373897410507 4.47467053410276e-22 BR00116991 NNC-55-0396 final compound A16 A549 24 791 ADCCM +0.27748158274474066 8.888396161498108e-22 BR00116993 BI-2536 final compound I14 A549 24 630 ADCCM +0.2764612954186414 1.0730359530331181e-21 BR00116991 ganetespib final compound M10 A549 24 633 ADCCM +0.2909584679496184 1.3326605536688597e-21 BR00116992 NVP-HSP990 final compound E23 A549 24 565 ADCCM +0.23236922236205 3.3273086349026813e-21 BR00116993 BAX-channel-blocker final compound I19 A549 24 871 ADCCM +0.28812360589739405 5.552509394643293e-21 BR00116991 BI-2536 final compound I14 A549 24 557 ADCCM +0.3772825235109718 7.0713610668602e-21 BR00116993 TG-101348 final compound M20 A549 24 319 ADCCM +0.272441050375134 8.203990298521579e-21 BR00116992 ganetespib final compound M10 A549 24 622 ADCCM +0.2977862566582298 1.3373617251397904e-20 BR00116993 BI-2536 final compound E21 A549 24 514 ADCCM +0.26848788339443797 1.3810038140756358e-20 BR00116993 AZ191 final compound I18 A549 24 636 ADCCM +0.3851942241203986 2.26253703811966e-20 BR00116992 NSC-632839 final compound M16 A549 24 298 ADCCM +0.3463263245426467 3.911736794651756e-20 BR00116991 NSC-632839 final compound M16 A549 24 368 ADCCM +0.23377741152772055 7.374151266364449e-20 BR00116991 AZ191 final compound I18 A549 24 809 ADCCM +0.31928204446806624 1.2254055466936792e-19 BR00116994 AZD7762 final compound K11 A549 24 424 ADCCM +0.36908517350157727 1.3422205692081872e-19 BR00116994 NSC-632839 final compound M16 A549 24 317 ADCCM +0.32959403779336355 1.4795887696301869e-19 BR00116993 NSC-632839 final compound M16 A549 24 394 ADCCM +0.3213639248689438 1.8328846340255205e-19 BR00116991 GK921 final compound H24 A549 24 413 ADCCM +0.2728457804690504 1.9351558182474262e-19 BR00116992 buparlisib final compound D11 A549 24 578 ADCCM +0.2379962986150766 1.945105496940347e-19 BR00116993 7-hydroxystaurosporine final compound L04 A549 24 764 ADCCM +0.2954719617265395 3.24219244140631e-19 BR00116994 buparlisib final compound L12 A549 24 485 ADCCM +0.23462343502012992 4.592183728443133e-19 BR00116994 aminopurvalanol-a final compound K03 A549 24 769 ADCCM +0.42731277533039647 5.639758415126758e-19 BR00116994 ponatinib final compound C20 A549 24 227 ADCCM +0.22009681148571253 6.157656471396926e-19 BR00116994 NNC-55-0396 final compound A16 A549 24 869 ADCCM +0.2715877868264066 7.033053166384504e-19 BR00116992 BI-2536 final compound E21 A549 24 568 ADCCM +0.2109704641350211 7.0443013845831815e-19 BR00116993 ingenol-mebutate final compound M11 A549 24 948 ADCCM +0.2801118558169523 1.8844097748605447e-18 BR00116992 epothilone-b final compound F07 A549 24 517 ADCCM +0.14963250430548347 2.6697368269127884e-18 BR00116992 LY2109761 final compound M02 A549 24 1822 ADCCM +0.3811223950068761 2.9409600709472854e-18 BR00116992 romidepsin final compound N19 A549 24 274 ADCCM +0.24706075055509044 3.2196115236221154e-18 BR00116993 ganetespib final compound M10 A549 24 662 ADCCM +0.22689715137598845 4.371396915749119e-18 BR00116993 NNC-55-0396 final compound A16 A549 24 779 ADCCM +0.2536440549060335 4.7594994694231414e-18 BR00116993 NVP-HSP990 final compound E23 A549 24 618 ADCCM +0.28269494454496036 5.605593776646466e-18 BR00116991 epothilone-b final compound F07 A549 24 494 ADCCM +0.15304596854008296 9.733688932822725e-18 BR00116994 LY2109761 final compound M02 A549 24 1690 ADCCM +0.2162090367846722 1.0606001927101759e-17 BR00116992 SU3327 final compound I20 A549 24 843 ADCCM +0.1938036224976168 1.1473062248009485e-17 BR00116991 ingenol-mebutate final compound M11 A549 24 1050 ADCCM +0.2553917553917554 1.605225854511246e-17 BR00116991 BI-2536 final compound E21 A549 24 594 ADCCM +0.14827555774032253 1.655866188690778e-17 BR00116993 LY2109761 final compound M02 A549 24 1777 ADCCM +0.17793768650261643 2.8317469151769136e-17 BR00116992 ingenol-mebutate final compound M11 A549 24 1217 ADCCM +0.2962617350978396 6.794227194776921e-17 BR00116991 AZD7762 final compound K11 A549 24 421 ADCCM +0.18960538979788258 9.738108181812542e-17 BR00116994 ingenol-mebutate final compound M11 A549 24 1039 ADCCM +0.2478892447683828 1.6289323495409313e-16 BR00116993 buparlisib final compound L12 A549 24 596 ADCCM +0.2509560880219807 2.589677950708936e-16 BR00116994 PF-03758309 final compound N21 A549 24 569 ADCCM +0.22180645474345073 2.608944172453801e-16 BR00116994 BAX-channel-blocker final compound I19 A549 24 733 ADCCM +0.37751004016064255 3.4225246403591607e-16 BR00116993 ponatinib final compound C20 A549 24 249 ADCCM +0.2236365493560883 3.842986778350225e-16 BR00116994 7-hydroxystaurosporine final compound L04 A549 24 711 ADCCM +0.22932107883363423 4.308397604351969e-16 BR00116993 aminopurvalanol-a final compound K03 A549 24 675 ADCCM +0.27629310344827585 5.065187744696617e-16 BR00116991 delanzomib final compound L11 A549 24 464 ADCCM 0.5182437986638581 7.424402465236568e-190 BR00116991 BQ-788 final compound E08 A549 24 1546 Anaphase 0.5512256184525092 8.961288015763519e-124 BR00116992 AMG900 final compound N09 A549 24 882 Anaphase 0.5922865013774105 1.5601219625644323e-118 BR00116991 PF-431396 final compound L20 A549 24 726 Anaphase @@ -19,6 +109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5582422778781686 3.182048032174767e-111 BR00116993 AMG900 final compound N09 A549 24 770 Anaphase 0.6232856927937416 3.0549787073930934e-105 BR00116994 epothilone-b final compound F07 A549 24 575 Anaphase 0.7015648772006086 1.1823979141252387e-101 BR00116991 oxibendazole final compound M19 A549 24 428 Anaphase +0.5395002770375452 4.873167377477751e-101 BR00116991 AMG900 final compound N09 A549 24 753 Anaphase +0.6573797747204788 1.5312870954234152e-100 BR00116992 briciclib final compound H01 A549 24 490 Anaphase +0.5788903369765903 4.9942238720802904e-99 BR00116994 danusertib final compound N18 A549 24 636 Anaphase +0.6681034482758621 1.564165646790535e-98 BR00116994 ixabepilone final compound J21 A549 24 464 Anaphase +0.662278148182928 1.0230814815906445e-96 BR00116991 ixabepilone final compound J21 A549 24 463 Anaphase +0.6135531135531136 2.9546488775110865e-96 BR00116994 briciclib final compound H01 A549 24 546 Anaphase +0.5874554847064454 3.4648732132544816e-96 BR00116993 epothilone-b final compound F07 A549 24 597 Anaphase +0.5246576203040583 5.7797650245369894e-96 BR00116993 danusertib final compound N18 A549 24 758 Anaphase +0.5644963923556943 6.14538554762166e-95 BR00116991 danusertib final compound N18 A549 24 641 Anaphase +0.5273436931628036 7.658644885007041e-95 BR00116994 PF-431396 final compound L20 A549 24 744 Anaphase +0.6403280330537123 9.696853730592741e-95 BR00116992 CYT-997 final compound C09 A549 24 489 Anaphase +0.644028425494115 1.4261299100854797e-93 BR00116992 oxibendazole final compound M19 A549 24 475 Anaphase +0.6736596736596736 8.4197964259454e-93 BR00116992 colchicine final compound K17 A549 24 429 Anaphase +0.650852075121725 8.117343335183555e-92 BR00116993 CYT-997 final compound E06 A549 24 456 Anaphase +0.6432867101006879 1.1910834003186934e-91 BR00116993 briciclib final compound H01 A549 24 467 Anaphase +0.5043520974555458 5.901512359208746e-91 BR00116994 geldanamycin final compound L01 A549 24 780 Anaphase +0.5752961082910322 9.871667173953357e-91 BR00116992 BI-2536 final compound I14 A549 24 591 Anaphase +0.5474836201310389 3.1398647772180724e-89 BR00116994 BI-2536 final compound I14 A549 24 645 Anaphase +0.5516822358927622 1.1537339657268813e-88 BR00116993 BI-2536 final compound I14 A549 24 630 Anaphase +0.6350348829177316 1.298627695529429e-88 BR00116993 oxibendazole final compound M19 A549 24 465 Anaphase +0.6149627189601876 4.120199443973433e-88 BR00116991 epothilone-b final compound F07 A549 24 494 Anaphase +0.6397921306607276 1.9764687800660547e-87 BR00116992 CYT-997 final compound E06 A549 24 450 Anaphase +0.5553517021757216 2.6621635720138963e-86 BR00116992 danusertib final compound N18 A549 24 603 Anaphase +0.5935143118468205 2.3693386868751607e-85 BR00116992 epothilone-b final compound F07 A549 24 517 Anaphase +0.5273049434050493 2.1024939195052136e-84 BR00116993 PF-431396 final compound L20 A549 24 659 Anaphase +0.62889002077341 2.5348290604090307e-83 BR00116991 colchicine final compound K17 A549 24 447 Anaphase +0.5897145498670981 1.5200030333376837e-82 BR00116993 CYT-997 final compound C09 A549 24 509 Anaphase +0.5913594497751485 1.8404718619202775e-81 BR00116991 briciclib final compound H01 A549 24 498 Anaphase +0.4965319189002574 1.5490400979057531e-80 BR00116994 ganetespib final compound M10 A549 24 712 Anaphase +0.610779131234199 2.2630685144641196e-80 BR00116994 oxibendazole final compound M19 A549 24 458 Anaphase +0.5227704687384297 3.6476442314025426e-80 BR00116993 danusertib final compound E05 A549 24 638 Anaphase +0.5761777039023838 2.53263163377485e-79 BR00116993 BI-2536 final compound E21 A549 24 514 Anaphase +0.4866429405549686 3.02584032772261e-79 BR00116991 fludarabine-phosphate final compound N12 A549 24 735 Anaphase +0.49221493957244394 1.0081358302001981e-78 BR00116994 GSK1070916 final compound C04 A549 24 709 Anaphase +0.4712607037623609 1.0083332199332006e-77 BR00116994 aminopurvalanol-a final compound K03 A549 24 769 Anaphase +0.6289156626506024 2.937602710852195e-77 BR00116994 colchicine final compound K17 A549 24 415 Anaphase +0.6495823139601022 6.735516430296147e-77 BR00116993 ixabepilone final compound J21 A549 24 383 Anaphase +0.5007228464085243 8.650567893370831e-77 BR00116991 NVP-HSP990 final compound E23 A549 24 668 Anaphase +0.513143159957606 1.0307851780199506e-76 BR00116994 danusertib final compound E05 A549 24 633 Anaphase +0.5432399824627092 3.47942605827096e-76 BR00116991 BI-2536 final compound I14 A549 24 557 Anaphase +0.525 6.628521261190265e-76 BR00116992 danusertib final compound E05 A549 24 600 Anaphase +0.6449629152556459 2.5305423915960725e-75 BR00116993 colchicine final compound K17 A549 24 381 Anaphase +0.4870551841767928 1.9916031044937094e-74 BR00116992 GSK1070916 final compound C04 A549 24 685 Anaphase +0.44776834939354715 3.5188601945207718e-74 BR00116994 fludarabine-phosphate final compound N12 A549 24 816 Anaphase +0.4646905710491368 9.327543465398065e-74 BR00116993 fludarabine-phosphate final compound N12 A549 24 753 Anaphase +0.4867135766104838 2.7197110646032128e-73 BR00116994 ganetespib final compound I17 A549 24 679 Anaphase +0.5214810017271158 3.215107494541077e-72 BR00116994 BI-2536 final compound E21 A549 24 576 Anaphase +0.5248644768434862 5.874633213230429e-72 BR00116992 BI-2536 final compound E21 A549 24 568 Anaphase +0.45530233773018153 6.215927665515063e-70 BR00116992 geldanamycin final compound L01 A549 24 741 Anaphase +0.47629082553750207 7.496609504474139e-70 BR00116993 aminopurvalanol-a final compound K03 A549 24 675 Anaphase +0.5201589744767856 5.992932409980464e-69 BR00116994 PHA-793887 final compound E13 A549 24 553 Anaphase +0.5029290654290655 6.147805452366833e-69 BR00116991 BI-2536 final compound E21 A549 24 594 Anaphase +0.45185700746357066 2.45156809726822e-68 BR00116991 geldanamycin final compound L01 A549 24 736 Anaphase +0.6104984149817523 3.0035233117151605e-68 BR00116994 CYT-997 final compound C09 A549 24 388 Anaphase +0.4761055483566969 2.542551085386454e-67 BR00116993 ganetespib final compound I17 A549 24 650 Anaphase +0.4388717790781234 8.196712240694292e-67 BR00116991 NSC-663284 final compound G06 A549 24 765 Anaphase +0.4469599330710442 3.016436956129374e-66 BR00116992 ganetespib final compound I17 A549 24 729 Anaphase +0.5586205163009326 7.145107794617227e-65 BR00116994 CYT-997 final compound E06 A549 24 447 Anaphase +0.45259386907475646 2.0833223165777867e-64 BR00116993 GSK1070916 final compound C04 A549 24 694 Anaphase +0.44999107148355 2.2472244782161063e-64 BR00116992 fludarabine-phosphate final compound N12 A549 24 697 Anaphase +0.4926160041204289 8.796597778326285e-63 BR00116992 NVP-HSP990 final compound E23 A549 24 565 Anaphase +0.45813586097946285 2.7682102960768306e-60 BR00116991 ganetespib final compound M10 A549 24 633 Anaphase +0.4271316127093471 1.2756025827783032e-59 BR00116992 aminopurvalanol-a final compound K03 A549 24 723 Anaphase +0.4570090279495424 3.7067521013936683e-59 BR00116992 ganetespib final compound M10 A549 24 622 Anaphase +0.5004940426529898 8.698619293459334e-59 BR00116994 NVP-HSP990 final compound E23 A549 24 511 Anaphase +0.4536784301057902 3.7532937415673505e-57 BR00116994 TG-02 final compound L21 A549 24 610 Anaphase +0.5349627918911983 4.370106372250833e-57 BR00116992 KG-5 final compound C13 A549 24 432 Anaphase +0.4341580824809813 1.4513612198622622e-56 BR00116993 ganetespib final compound M10 A549 24 662 Anaphase +0.4435121672382819 6.554074168198274e-56 BR00116993 PHA-793887 final compound I06 A549 24 628 Anaphase +0.4447346750378961 1.093311973783198e-55 BR00116993 NVP-HSP990 final compound E23 A549 24 618 Anaphase +0.49292929292929294 5.946097952555271e-55 BR00116992 PHA-793887 final compound E13 A549 24 495 Anaphase +0.5177786528453294 2.078881772243986e-53 BR00116991 KG-5 final compound C13 A549 24 433 Anaphase +0.45037843067615396 1.2658664324159028e-52 BR00116991 ganetespib final compound I17 A549 24 571 Anaphase +0.32148916028530994 2.5672426891786893e-52 BR00116991 polydatin final compound K08 A549 24 1132 Anaphase +0.5156547527851343 3.2117890022334293e-52 BR00116994 KG-5 final compound C13 A549 24 427 Anaphase +0.47984561511131557 5.025523657928416e-51 BR00116994 PHA-793887 final compound I06 A549 24 483 Anaphase +0.43345654128117656 6.625041448156234e-51 BR00116992 PHA-793887 final compound I06 A549 24 598 Anaphase +0.4540405002221799 3.801823223026059e-50 BR00116993 TG-02 final compound L21 A549 24 531 Anaphase +0.4541481114959591 9.13478021865721e-49 BR00116993 PHA-793887 final compound E13 A549 24 517 Anaphase +0.28205446174900295 1.243519798599724e-47 BR00116992 polydatin final compound K08 A549 24 1346 Anaphase +0.40253565768621236 4.476747854372761e-46 BR00116991 danusertib final compound E05 A549 24 631 Anaphase +0.4713656387665198 5.766149573614885e-46 BR00116993 KG-5 final compound C13 A549 24 454 Anaphase +0.2977666579986502 1.4830107583018902e-45 BR00116991 AC-710 final compound I03 A549 24 1154 Anaphase +0.25696637929641275 7.580785106165529e-44 BR00116991 PETCM final compound I04 A549 24 1492 Anaphase +0.3586132292023957 1.172709924852024e-43 BR00116994 AZ191 final compound I18 A549 24 755 Anaphase +0.464250329407679 1.85180217550748e-43 BR00116991 PHA-793887 final compound E13 A549 24 442 Anaphase +0.43137254901960786 5.574162638884407e-43 BR00116991 TG-02 final compound L21 A549 24 510 Anaphase +0.45080584707646176 5.938243773236502e-43 BR00116991 delanzomib final compound L11 A549 24 464 Anaphase +0.2521976729475207 2.6901013531401615e-40 BR00116994 polydatin final compound K08 A549 24 1421 Anaphase +0.40409683426443205 1.399949295421157e-39 BR00116993 PF-03758309 final compound N21 A549 24 537 Anaphase 0.5861109566442381 1.9640799227812946e-117 BR00116991 fludarabine-phosphate final compound N12 A549 24 735 Apoptosis 0.5649243027888446 3.1568017044754155e-111 BR00116993 fludarabine-phosphate final compound N12 A549 24 753 Apoptosis 0.5103552423414354 2.388609098875517e-97 BR00116994 fludarabine-phosphate final compound N12 A549 24 816 Apoptosis @@ -29,6 +209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.44518789021086114 1.1616505785163137e-58 BR00116993 ganetespib final compound I17 A549 24 650 Apoptosis 0.4249733224530789 1.9921348902790514e-58 BR00116994 ganetespib final compound M10 A549 24 712 Apoptosis 0.414664141743938 8.968473386487846e-58 BR00116992 geldanamycin final compound L01 A549 24 741 Apoptosis +0.2862561683047186 1.9981832727709512e-56 BR00116991 BQ-788 final compound E08 A549 24 1546 Apoptosis +0.41278508871101466 3.0674293272571514e-56 BR00116992 ganetespib final compound I17 A549 24 729 Apoptosis +0.4271655998687018 8.32539973891033e-56 BR00116993 aminopurvalanol-a final compound K03 A549 24 675 Apoptosis +0.4275301855305782 2.2045560040688303e-55 BR00116991 NVP-HSP990 final compound E23 A549 24 668 Apoptosis +0.4892450231626393 1.3225950975667193e-53 BR00116992 CYT-997 final compound C09 A549 24 489 Apoptosis +0.4265402843601896 4.892879810897463e-52 BR00116991 ganetespib final compound M10 A549 24 633 Apoptosis +0.4971307674472525 8.027781426433139e-52 BR00116993 CYT-997 final compound E06 A549 24 456 Apoptosis +0.2523055509843387 1.6006929816559258e-51 BR00116992 LY2109761 final compound M02 A549 24 1822 Apoptosis +0.3853033990612229 1.8686020950308617e-51 BR00116994 aminopurvalanol-a final compound K03 A549 24 769 Apoptosis +0.4971336689038031 1.185750082622709e-50 BR00116991 colchicine final compound K17 A549 24 447 Apoptosis +0.49426211693110195 3.2461676640096e-48 BR00116991 oxibendazole final compound M19 A549 24 428 Apoptosis +0.27503577951909164 8.20610960541477e-48 BR00116994 polydatin final compound K08 A549 24 1421 Apoptosis +0.45039870565121926 5.368612298477299e-47 BR00116993 CYT-997 final compound C09 A549 24 509 Apoptosis +0.24304151194309398 1.153360383951934e-46 BR00116993 LY2109761 final compound M02 A549 24 1777 Apoptosis +0.27495831331117426 3.2036688903727995e-45 BR00116992 polydatin final compound K08 A549 24 1346 Apoptosis +0.4494658963381687 4.865001869118362e-45 BR00116992 briciclib final compound H01 A549 24 490 Apoptosis +0.4156001616597063 8.508758254742089e-45 BR00116991 ganetespib final compound I17 A549 24 571 Apoptosis +0.37097246462241434 1.340171731126249e-44 BR00116992 aminopurvalanol-a final compound K03 A549 24 723 Apoptosis +0.4359532331919769 3.437053249581258e-44 BR00116994 NVP-HSP990 final compound E23 A549 24 511 Apoptosis +0.40567183281047586 3.567488409636484e-42 BR00116992 NVP-HSP990 final compound E23 A549 24 565 Apoptosis +0.3735440250427693 1.1223651600834813e-41 BR00116993 ganetespib final compound M10 A549 24 662 Apoptosis +0.3845793140407288 1.33736070613267e-41 BR00116992 ganetespib final compound M10 A549 24 622 Apoptosis +0.43950507300173225 9.210176807187803e-40 BR00116992 CYT-997 final compound E06 A549 24 450 Apoptosis +0.4320743541847009 9.616187068553407e-40 BR00116993 briciclib final compound H01 A549 24 467 Apoptosis +0.4173700791188707 1.738479539506541e-39 BR00116991 briciclib final compound H01 A549 24 498 Apoptosis +0.4247834776815456 4.05764070605274e-39 BR00116992 oxibendazole final compound M19 A549 24 475 Apoptosis +0.2880382775119617 1.3426518075510283e-38 BR00116991 dexamethasone final compound A21 A549 24 1045 Apoptosis +0.3956043956043956 1.5597000966077985e-38 BR00116994 briciclib final compound H01 A549 24 546 Apoptosis +0.3336270810796549 1.087599470456413e-37 BR00116994 AZ191 final compound I18 A549 24 755 Apoptosis +0.36709624291251647 1.1492003974146083e-37 BR00116993 NVP-HSP990 final compound E23 A549 24 618 Apoptosis +0.4382284382284382 2.1066835587863954e-37 BR00116992 colchicine final compound K17 A549 24 429 Apoptosis +0.37900071783955047 8.316922826710865e-37 BR00116994 PF-03758309 final compound N21 A549 24 569 Apoptosis +0.39509274300177555 2.557883901493107e-36 BR00116993 BI-2536 final compound E21 A549 24 514 Apoptosis +0.3781718334469417 3.4039842625555347e-36 BR00116991 BI-2536 final compound I14 A549 24 557 Apoptosis +0.22996742671009773 5.494620611124446e-36 BR00116994 PP-2 final compound J10 A549 24 1535 Apoptosis +0.3982374245472837 7.309422412230943e-36 BR00116991 PF-03758309 final compound N21 A549 24 497 Apoptosis +0.41145647478636493 1.4128801390577555e-35 BR00116991 ixabepilone final compound J21 A549 24 463 Apoptosis +0.2556104621675538 2.219177453527412e-34 BR00116993 polydatin final compound K08 A549 24 1177 Apoptosis +0.4108890732222306 2.343052575640519e-34 BR00116994 CYT-997 final compound E06 A549 24 447 Apoptosis +0.3098258449380627 5.954204352139522e-34 BR00116991 NNC-55-0396 final compound A16 A549 24 791 Apoptosis +0.21230320003930736 7.950709913859922e-34 BR00116994 LY2109761 final compound M02 A549 24 1690 Apoptosis +0.3716484573627431 1.0787373923005869e-33 BR00116992 PF-03758309 final compound N21 A549 24 539 Apoptosis +0.43524734276352595 1.079186820484913e-33 BR00116994 CYT-997 final compound C09 A549 24 388 Apoptosis +0.32565682914769917 9.685015513193528e-33 BR00116991 7-hydroxystaurosporine final compound L04 A549 24 684 Apoptosis +0.23206421061011268 1.2898826771490597e-32 BR00116993 PP-2 final compound J10 A549 24 1364 Apoptosis +0.3920333402408418 1.8689868812202164e-32 BR00116993 oxibendazole final compound M19 A549 24 465 Apoptosis +0.41445783132530123 2.6850358286725566e-32 BR00116994 colchicine final compound K17 A549 24 415 Apoptosis +0.26900195140693406 3.3522591569566296e-32 BR00116991 fludarabine final compound B06 A549 24 994 Apoptosis +0.331024531024531 5.148817014325377e-31 BR00116993 BI-2536 final compound I14 A549 24 630 Apoptosis +0.3401015228426396 1.0928697502729469e-30 BR00116992 BI-2536 final compound I14 A549 24 591 Apoptosis +0.22934886125547604 4.149336028217641e-30 BR00116992 PP-2 final compound J10 A549 24 1287 Apoptosis +0.4144308984875585 5.106810249298416e-30 BR00116993 ixabepilone final compound J21 A549 24 383 Apoptosis +0.3042827994691072 1.6250532277703338e-29 BR00116992 AZ191 final compound I18 A549 24 710 Apoptosis +0.34279938169299284 2.181590168940953e-29 BR00116994 PHA-793887 final compound E13 A549 24 553 Apoptosis +0.29451137884872824 5.755821365515059e-29 BR00116991 SU3327 final compound I20 A549 24 747 Apoptosis +0.23302647050388597 1.102055570326534e-28 BR00116991 A-987306 final compound P20 A549 24 1180 Apoptosis +0.29614325068870523 1.778317952819031e-28 BR00116991 PF-431396 final compound L20 A549 24 726 Apoptosis +0.3683095952023988 1.797637749324852e-28 BR00116991 delanzomib final compound L11 A549 24 464 Apoptosis +0.22303823244225265 4.436619495168234e-28 BR00116991 loperamide final compound P23 A549 24 1269 Apoptosis +0.31270678708754357 6.916182832334388e-28 BR00116993 AZ191 final compound I18 A549 24 636 Apoptosis +0.374703334362129 1.619481312814632e-27 BR00116991 KG-5 final compound C13 A549 24 433 Apoptosis +0.3975096780448618 2.0339422363521235e-27 BR00116993 colchicine final compound K17 A549 24 381 Apoptosis +0.2321103310807222 2.615659056731105e-27 BR00116991 polydatin final compound K08 A549 24 1132 Apoptosis +0.23448905109489052 7.867515184525973e-27 BR00116991 quinine final compound A05 A549 24 1096 Apoptosis +0.3333333333333333 8.149383178168298e-27 BR00116993 PF-03758309 final compound N21 A549 24 537 Apoptosis +0.34545454545454546 1.3719325795241235e-26 BR00116992 PHA-793887 final compound E13 A549 24 495 Apoptosis +0.30097199222406223 2.949095833409218e-26 BR00116994 BI-2536 final compound I14 A549 24 645 Apoptosis +0.3300270450136641 4.752317750785514e-26 BR00116992 ixabepilone final compound J21 A549 24 531 Apoptosis +0.36035667957059536 5.667878868581103e-26 BR00116991 PHA-793887 final compound E13 A549 24 442 Apoptosis +0.27417080033849095 9.918738243038777e-26 BR00116993 7-hydroxystaurosporine final compound L04 A549 24 764 Apoptosis +0.19609428449834707 1.200875457935221e-25 BR00116991 PETCM final compound I04 A549 24 1492 Apoptosis +0.3333333333333333 1.7349050109508589e-25 BR00116991 TG-02 final compound L21 A549 24 510 Apoptosis +0.2646232965557234 2.1642160865361326e-25 BR00116991 AZ191 final compound I18 A549 24 809 Apoptosis +0.30077347775098495 3.5227379042780295e-25 BR00116992 PP-121 final compound B16 A549 24 615 Apoptosis +0.3081552245250432 9.256617916155456e-25 BR00116994 BI-2536 final compound E21 A549 24 576 Apoptosis +0.3010226135226135 3.066652948742177e-24 BR00116991 BI-2536 final compound E21 A549 24 594 Apoptosis +0.21318810678075517 3.443667547668301e-24 BR00116991 desonide final compound E16 A549 24 1194 Apoptosis +0.31593982098647877 5.7646261985048154e-24 BR00116993 TG-02 final compound L21 A549 24 531 Apoptosis +0.3 7.969946771228692e-24 BR00116993 PP-121 final compound B16 A549 24 590 Apoptosis +0.2184950135992747 1.8086273599972e-23 BR00116991 JTE-607 final compound C14 A549 24 1103 Apoptosis +0.2915260168510592 1.9110047800841408e-23 BR00116994 TG-02 final compound L21 A549 24 610 Apoptosis +0.33480176211453744 6.209166620727774e-23 BR00116993 KG-5 final compound C13 A549 24 454 Apoptosis +0.20961140448018414 6.292320430279099e-23 BR00116993 desonide final compound E16 A549 24 1167 Apoptosis +0.2278544411654682 7.99311627805965e-23 BR00116992 dexamethasone final compound A21 A549 24 982 Apoptosis +0.34080168505688135 1.0828979333190898e-22 BR00116992 KG-5 final compound C13 A549 24 432 Apoptosis +0.23156454327886497 2.1300785509153012e-22 BR00116991 DDR1-IN-1 final compound A23 A549 24 935 Apoptosis +0.3254310344827586 3.894322132140913e-22 BR00116994 ixabepilone final compound J21 A549 24 464 Apoptosis +0.1896048877764243 5.173246427102484e-22 BR00116991 NVS-PAK1-1 final compound N14 A549 24 1374 Apoptosis +0.2617195415085719 5.940484583931741e-22 BR00116992 7-hydroxystaurosporine final compound L04 A549 24 709 Apoptosis +0.2161173304925199 7.651498865646647e-22 BR00116993 fludarabine final compound B06 A549 24 1042 Apoptosis 0.49176555884568973 2.1047210019140373e-170 BR00116991 BQ-788 final compound E08 A549 24 1546 Binuclear 0.4306569343065693 1.2956611277620124e-91 BR00116991 quinine final compound A05 A549 24 1096 Binuclear 0.36712504645407174 9.999809539233799e-86 BR00116994 polydatin final compound K08 A549 24 1421 Binuclear @@ -39,6 +309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2292940453822371 1.5096526192960176e-42 BR00116992 LY2109761 final compound M02 A549 24 1822 Binuclear 0.22369809979049646 1.9537183722560367e-39 BR00116993 LY2109761 final compound M02 A549 24 1777 Binuclear 0.5012740882306099 5.120646762115484e-32 BR00116991 AR-12 final compound C10 A549 24 273 Binuclear +0.5276234567901235 3.3406548024620044e-31 BR00116993 AR-12 final compound C10 A549 24 240 Binuclear +0.23957395446435417 1.7675895164687167e-29 BR00116991 AC-710 final compound I03 A549 24 1154 Binuclear +0.3271186440677966 2.4869899680417314e-28 BR00116993 PP-121 final compound B16 A549 24 590 Binuclear +0.20075499785415046 7.144872375114231e-27 BR00116991 PETCM final compound I04 A549 24 1492 Binuclear +0.2764342289699897 1.7862328693741123e-26 BR00116993 AMG900 final compound N09 A549 24 770 Binuclear +0.4632119788608338 1.0082922279941939e-25 BR00116994 AR-12 final compound C10 A549 24 260 Binuclear +0.3004835883042785 3.9288725286340048e-25 BR00116992 PP-121 final compound B16 A549 24 615 Binuclear +0.29805574542416646 4.304012001117773e-25 BR00116993 BI-2536 final compound I14 A549 24 630 Binuclear +0.2475066949856866 3.0073412347170575e-24 BR00116992 AMG900 final compound N09 A549 24 882 Binuclear +0.29947460595446584 5.447070988531888e-23 BR00116994 PP-121 final compound B16 A549 24 571 Binuclear +0.17980456026058633 4.346933654900557e-22 BR00116994 PP-2 final compound J10 A549 24 1535 Binuclear +0.17115963696856115 4.630487357413506e-22 BR00116994 LY2109761 final compound M02 A549 24 1690 Binuclear +0.2439174936478259 6.836552809213078e-22 BR00116994 fludarabine-phosphate final compound N12 A549 24 816 Binuclear +0.18452912434404872 7.710440931164429e-21 BR00116993 PP-2 final compound J10 A549 24 1364 Binuclear +0.3449197860962567 4.0001817364244263e-20 BR00116991 LDN-212854 final compound K01 A549 24 374 Binuclear +0.23290031855045393 1.5684488267107968e-19 BR00116994 AMG900 final compound N09 A549 24 798 Binuclear +0.23947301302516205 1.8156108907313197e-19 BR00116991 AMG900 final compound N09 A549 24 753 Binuclear +0.2656514382402707 9.646662935579058e-19 BR00116992 BI-2536 final compound I14 A549 24 591 Binuclear +0.23735750430962577 1.3670027252270799e-18 BR00116991 fludarabine-phosphate final compound N12 A549 24 735 Binuclear +0.40969162995594716 1.9795536265141654e-17 BR00116994 ponatinib final compound C20 A549 24 227 Binuclear +0.3895582329317269 3.04394497086012e-17 BR00116993 ponatinib final compound C20 A549 24 249 Binuclear +0.21283398513299698 1.0578914629754897e-16 BR00116994 KU-60019 final compound I07 A549 24 817 Binuclear +0.23590371277029784 3.2951709741923465e-16 BR00116994 BI-2536 final compound I14 A549 24 645 Binuclear +0.22671415366211733 4.2997910679668154e-16 BR00116993 GSK1070916 final compound C04 A549 24 694 Binuclear +0.22199555396309867 4.613076125352452e-16 BR00116992 aminopurvalanol-a final compound K03 A549 24 723 Binuclear +0.24385749385749386 5.752360862748721e-16 BR00116991 BI-2536 final compound E21 A549 24 594 Binuclear +0.31043956043956045 6.814759345476086e-16 BR00116994 romidepsin final compound N19 A549 24 364 Binuclear +0.1786038077969175 8.813388606499088e-16 BR00116991 JTE-607 final compound C14 A549 24 1103 Binuclear +0.222313928322512 1.0481832015361658e-15 BR00116993 KU-60019 final compound I07 A549 24 702 Binuclear +0.15435392669358558 1.4027041881616081e-15 BR00116991 hexestrol final compound A04 A549 24 1448 Binuclear +0.18346422862767073 1.575672470157755e-15 BR00116994 fludarabine final compound B06 A549 24 1019 Binuclear +0.29644663838120106 1.7624446867584826e-15 BR00116994 TG-101348 final compound M20 A549 24 384 Binuclear +0.15113053239974858 2.139307310318742e-15 BR00116991 diltiazem final compound O04 A549 24 1493 Binuclear +0.20902716988896927 3.3677836210922373e-15 BR00116994 aminopurvalanol-a final compound K03 A549 24 769 Binuclear +0.21070916334661355 4.481864626072161e-15 BR00116993 fludarabine-phosphate final compound N12 A549 24 753 Binuclear +0.1418687701507805 4.694381880860678e-15 BR00116991 salicylic-acid final compound O03 A549 24 1657 Binuclear +0.23838694588370754 6.167245684669495e-15 BR00116994 BI-2536 final compound E21 A549 24 576 Binuclear +0.15064758009543286 6.1916217628990046e-15 BR00116991 trihexyphenidyl final compound E02 A549 24 1467 Binuclear +0.20711957541937576 6.538084808768279e-15 BR00116992 KU-60019 final compound I07 A549 24 765 Binuclear +0.6237002805743522 1.045818545203059e-14 BR00116993 zaprinast final compound O01 A549 24 83 Binuclear +0.37373577749683945 1.3713702519174908e-14 BR00116992 AR-12 final compound C10 A549 24 224 Binuclear +0.23602688185351123 2.3021222674948627e-14 BR00116992 BI-2536 final compound E21 A549 24 568 Binuclear +0.31079545454545454 4.362078370012462e-14 BR00116993 TG-101348 final compound M20 A549 24 319 Binuclear +0.15984609351482865 7.493838007881787e-14 BR00116991 arcyriaflavin-a final compound B04 A549 24 1204 Binuclear +0.13747068269410795 1.0675725135201946e-13 BR00116991 sacubitril final compound E04 A549 24 1603 Binuclear +0.23616236162361623 1.1493476074023229e-13 BR00116991 PHA-793887 final compound I06 A549 24 542 Binuclear +0.2070286923520586 1.3606704430140754e-13 BR00116992 fludarabine-phosphate final compound N12 A549 24 697 Binuclear +0.2007685700746357 1.901588732680733e-13 BR00116991 geldanamycin final compound L01 A549 24 736 Binuclear +0.16727493135211086 3.0913138388800293e-13 BR00116993 fludarabine final compound B06 A549 24 1042 Binuclear +0.18846980259061666 4.5474298773141665e-13 BR00116993 JTE-607 final compound C14 A549 24 808 Binuclear +0.2639225181598063 4.71916939023155e-13 BR00116992 TG-101348 final compound M20 A549 24 413 Binuclear +0.1368735976065819 6.085276593048182e-13 BR00116991 phenolphthalein final compound O05 A549 24 1528 Binuclear +0.15366658063035935 1.1942667643367461e-12 BR00116991 A-987306 final compound P20 A549 24 1180 Binuclear +0.29801777170198224 1.5631422087814257e-12 BR00116993 romidepsin final compound N19 A549 24 304 Binuclear +0.14398156966250353 3.9586487105878104e-12 BR00116992 PP-2 final compound J10 A549 24 1287 Binuclear +0.299015116811727 4.2652670868580905e-12 BR00116993 puromycin final compound C22 A549 24 295 Binuclear +0.1546023235031278 4.403851237612573e-12 BR00116991 thioguanine final compound N04 A549 24 1119 Binuclear +0.1629215646014065 1.1096867139953887e-11 BR00116991 azeliragon final compound C08 A549 24 968 Binuclear +0.2220052132522383 1.420908422017831e-11 BR00116993 BI-2536 final compound E21 A549 24 514 Binuclear +0.21163504372215805 2.716739828408283e-11 BR00116991 PP-121 final compound B16 A549 24 550 Binuclear +0.11482809383883935 3.927147985812647e-11 BR00116993 formononetin final compound K02 A549 24 1853 Binuclear +0.11903587281188753 3.9410879680101334e-11 BR00116993 trihexyphenidyl final compound E02 A549 24 1726 Binuclear +0.1416467099857285 4.429282922616977e-11 BR00116992 ingenol-mebutate final compound M11 A549 24 1217 Binuclear +0.12034470704934992 4.6283869296881557e-11 BR00116993 droxinostat final compound N05 A549 24 1682 Binuclear +0.21064728921871778 4.793789446460318e-11 BR00116992 PF-03758309 final compound N21 A549 24 539 Binuclear +0.16125303324932666 5.6816219076740336e-11 BR00116991 SRC-kinase-inhibitor-I final compound C23 A549 24 922 Binuclear +0.1815137902833912 9.945689110656587e-11 BR00116994 GSK1070916 final compound C04 A549 24 709 Binuclear +0.12506423953307547 1.1998161578033274e-10 BR00116991 YC-1 final compound G03 A549 24 1499 Binuclear +0.14520547945205478 1.750942204292177e-10 BR00116991 amlodipine final compound A03 A549 24 1095 Binuclear +0.12176165803108809 2.1779222740027792e-10 BR00116991 niflumic-acid final compound O06 A549 24 1544 Binuclear +0.17233455566181174 2.3077772102801702e-10 BR00116993 7-hydroxystaurosporine final compound L04 A549 24 764 Binuclear +0.17526917463301314 3.1532743059148626e-10 BR00116991 GSK1070916 final compound C04 A549 24 724 Binuclear +0.12036058734286953 3.6465021725163723e-10 BR00116991 A205804 final compound M06 A549 24 1536 Binuclear +0.17168658698539177 3.698885162287092e-10 BR00116993 azeliragon final compound C08 A549 24 753 Binuclear +0.1167481662591687 3.959130796822363e-10 BR00116991 zamifenacin final compound G02 A549 24 1636 Binuclear +0.197985771752801 4.5199973870851497e-10 BR00116991 BI-2536 final compound I14 A549 24 557 Binuclear +0.25631795474581254 4.934153008386874e-10 BR00116991 TG-101348 final compound M20 A549 24 328 Binuclear +0.12615923759744652 7.409070419723723e-10 BR00116991 LY2109761 final compound M02 A549 24 1357 Binuclear +0.21303393429054662 7.942664512153606e-10 BR00116993 UNC1999 final compound H19 A549 24 471 Binuclear +0.1464121411888416 8.131981787291856e-10 BR00116991 fludarabine final compound B06 A549 24 994 Binuclear +0.13812713904321408 9.9151044739762e-10 BR00116992 fludarabine final compound B06 A549 24 1118 Binuclear +0.336996336996337 1.051556069353712e-09 BR00116992 ponatinib final compound C20 A549 24 183 Binuclear +0.1418967714911948 1.1223221359922557e-09 BR00116992 JTE-607 final compound C14 A549 24 1053 Binuclear +0.23099036568942297 1.1698931091193006e-09 BR00116991 puromycin final compound C22 A549 24 392 Binuclear +0.12842262229723195 1.4627253211574286e-09 BR00116991 AZD1283 final compound P19 A549 24 1267 Binuclear +0.17667068569516203 1.6457308081644812e-09 BR00116993 PF-431396 final compound L20 A549 24 659 Binuclear +0.1240919100473786 1.7757472232493454e-09 BR00116991 regorafenib final compound P13 A549 24 1340 Binuclear +0.12689639778437173 1.7763762660868858e-09 BR00116991 deferasirox final compound L14 A549 24 1282 Binuclear +0.2538511629799963 1.8922002789359837e-09 BR00116991 romidepsin final compound N19 A549 24 314 Binuclear +0.19553072625698323 2.164739953676435e-09 BR00116993 PF-03758309 final compound N21 A549 24 537 Binuclear 0.39647517909976787 4.040606201523006e-80 BR00116991 polydatin final compound K08 A549 24 1132 Elongated 0.3494769469197985 1.3941227584285657e-77 BR00116994 polydatin final compound K08 A549 24 1421 Elongated 0.381592720193779 5.9886615915601936e-77 BR00116993 polydatin final compound K08 A549 24 1177 Elongated @@ -49,6 +409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5732463142079068 1.0119011511141417e-70 BR00116991 ixabepilone final compound J21 A549 24 463 Elongated 0.4867395762132604 3.9157212833631224e-68 BR00116993 BI-2536 final compound I14 A549 24 630 Elongated 0.5239652804327202 4.155681790027714e-67 BR00116992 ixabepilone final compound J21 A549 24 531 Elongated +0.47778337773297813 4.296016374782379e-67 BR00116994 BI-2536 final compound I14 A549 24 645 Elongated +0.42709345509319097 5.45891153113302e-66 BR00116994 AMG900 final compound N09 A549 24 798 Elongated +0.49238578680203043 2.177796322649812e-65 BR00116992 BI-2536 final compound I14 A549 24 591 Elongated +0.5522712453814388 1.512880550288996e-60 BR00116991 oxibendazole final compound M19 A549 24 428 Elongated +0.4843652492823472 6.680145564768755e-60 BR00116991 BI-2536 final compound I14 A549 24 557 Elongated +0.5299578792796971 3.108155365489853e-59 BR00116993 CYT-997 final compound E06 A549 24 456 Elongated +0.4606253981253981 1.6873643686018628e-57 BR00116991 BI-2536 final compound E21 A549 24 594 Elongated +0.47985347985347987 2.7630954388341847e-57 BR00116994 briciclib final compound H01 A549 24 546 Elongated +0.4607010681510456 7.035178239471972e-56 BR00116994 epothilone-b final compound F07 A549 24 575 Elongated +0.4850246652572234 1.0965747454688596e-55 BR00116992 epothilone-b final compound F07 A549 24 517 Elongated +0.5026160337552743 5.37144722859404e-55 BR00116992 oxibendazole final compound M19 A549 24 475 Elongated +0.48824369386546373 3.6541545852301e-54 BR00116991 epothilone-b final compound F07 A549 24 494 Elongated +0.5469185803471694 7.249712883257305e-53 BR00116993 ixabepilone final compound J21 A549 24 383 Elongated +0.4821355833575793 4.068436766596776e-52 BR00116992 briciclib final compound H01 A549 24 490 Elongated +0.4492530755711775 4.459281968043325e-52 BR00116992 BI-2536 final compound E21 A549 24 568 Elongated +0.47711805305052546 6.63112908412757e-52 BR00116991 briciclib final compound H01 A549 24 498 Elongated +0.43660046056419116 5.551311036602091e-50 BR00116994 BI-2536 final compound E21 A549 24 576 Elongated +0.4849137931034483 8.2743748305310815e-50 BR00116994 ixabepilone final compound J21 A549 24 464 Elongated +0.49042225950782997 3.077400582189874e-49 BR00116991 colchicine final compound K17 A549 24 447 Elongated +0.4771242425623035 7.52766616043415e-49 BR00116993 briciclib final compound H01 A549 24 467 Elongated +0.46475105379575143 3.0197239155677194e-48 BR00116992 CYT-997 final compound C09 A549 24 489 Elongated +0.45367383174039516 3.993804921274645e-48 BR00116993 BI-2536 final compound E21 A549 24 514 Elongated +0.41792717086834735 2.5883412672663175e-47 BR00116993 epothilone-b final compound F07 A549 24 597 Elongated +0.4987951807228916 2.8068602344417842e-47 BR00116994 colchicine final compound K17 A549 24 415 Elongated +0.44452020493855693 9.260128233504323e-46 BR00116993 CYT-997 final compound C09 A549 24 509 Elongated +0.4663104267218264 1.3198670529866345e-45 BR00116994 oxibendazole final compound M19 A549 24 458 Elongated +0.47055679287305124 1.360189741638477e-45 BR00116992 CYT-997 final compound E06 A549 24 450 Elongated +0.4670235523249008 4.074587125809698e-43 BR00116991 KG-5 final compound C13 A549 24 433 Elongated +0.364477525848139 1.6845107890101702e-42 BR00116994 GSK1070916 final compound C04 A549 24 709 Elongated +0.4463125417328636 2.8230807881515056e-42 BR00116993 oxibendazole final compound M19 A549 24 465 Elongated +0.49007957118816614 4.015927229449311e-42 BR00116993 colchicine final compound K17 A549 24 381 Elongated +0.4813926849409947 2.190000316853399e-41 BR00116994 CYT-997 final compound C09 A549 24 388 Elongated +0.45454545454545453 2.558027591823517e-40 BR00116992 colchicine final compound K17 A549 24 429 Elongated +0.43947917452178065 2.856441849447347e-39 BR00116994 CYT-997 final compound E06 A549 24 447 Elongated +0.3391188251001335 1.468587447487482e-38 BR00116992 PF-431396 final compound L20 A549 24 749 Elongated +0.3333333333333333 4.1121234153498075e-36 BR00116991 PF-431396 final compound L20 A549 24 726 Elongated +0.3365393872433285 1.3325410706730789e-33 BR00116993 PF-431396 final compound L20 A549 24 659 Elongated +0.3263134559964531 3.838134070188511e-33 BR00116993 GSK1070916 final compound C04 A549 24 694 Elongated +0.32569788013941714 1.0169744183213583e-32 BR00116992 GSK1070916 final compound C04 A549 24 685 Elongated +0.31079124652611057 3.82608921714951e-32 BR00116994 PF-431396 final compound L20 A549 24 744 Elongated +0.40109763838122964 3.5182366360714663e-31 BR00116994 KG-5 final compound C13 A549 24 427 Elongated +0.3132435848069271 5.056568215750609e-28 BR00116994 danusertib final compound N18 A549 24 636 Elongated +0.38498789346246975 1.1279370319098022e-27 BR00116992 TG-101348 final compound M20 A549 24 413 Elongated +0.2856250429838839 1.282428240498114e-26 BR00116991 GSK1070916 final compound C04 A549 24 724 Elongated +0.18094077626077767 6.954941822252952e-26 BR00116993 LY2109761 final compound M02 A549 24 1777 Elongated +0.17819999746824913 8.21373270354418e-26 BR00116992 LY2109761 final compound M02 A549 24 1822 Elongated +0.28259368526771705 1.374270087003457e-25 BR00116994 ganetespib final compound M10 A549 24 712 Elongated +0.3502202643171806 4.22057007440959e-25 BR00116993 KG-5 final compound C13 A549 24 454 Elongated +0.3039634481672062 3.062387184396449e-24 BR00116991 buparlisib final compound L12 A549 24 581 Elongated +0.3479706611923702 9.580457547218761e-24 BR00116992 KG-5 final compound C13 A549 24 432 Elongated +0.25501522742902055 8.671190067016165e-23 BR00116994 geldanamycin final compound L01 A549 24 780 Elongated +0.17330469512237923 1.282670191018106e-22 BR00116994 LY2109761 final compound M02 A549 24 1690 Elongated +0.38635027916544223 1.5994020226629527e-22 BR00116991 TG-101348 final compound M20 A549 24 328 Elongated +0.26925871379479627 3.8513094950511193e-22 BR00116994 ganetespib final compound I17 A549 24 679 Elongated +0.27444030311258116 1.1507815846548082e-21 BR00116993 danusertib final compound E05 A549 24 638 Elongated +0.282290696666415 1.938390912683005e-21 BR00116991 UNC2025 final compound N06 A549 24 597 Elongated +0.27820752274067095 3.800361503497535e-21 BR00116992 danusertib final compound N18 A549 24 603 Elongated +0.380221394984326 4.633846794817289e-21 BR00116993 TG-101348 final compound M20 A549 24 319 Elongated +0.24751155226089264 6.6781255278732835e-21 BR00116993 danusertib final compound N18 A549 24 758 Elongated +0.2064839765224031 2.968591426865225e-20 BR00116991 dexamethasone final compound O02 A549 24 1063 Elongated +0.27443779213871 3.429558053780546e-20 BR00116993 buparlisib final compound L12 A549 24 596 Elongated +0.26335315912636503 4.002065542444617e-20 BR00116991 danusertib final compound N18 A549 24 641 Elongated +0.2895209977478756 1.9231629732316004e-19 BR00116993 buparlisib final compound D11 A549 24 513 Elongated +0.2634256642170718 3.536260205938132e-19 BR00116994 TG-02 final compound L21 A549 24 610 Elongated +0.29055142726595 4.410147004690768e-19 BR00116991 anisomycin final compound N03 A549 24 498 Elongated +0.2354971927848598 4.51320119666827e-19 BR00116992 KU-60019 final compound I07 A549 24 765 Elongated +0.23628752099768696 4.981304207614299e-19 BR00116994 AZ191 final compound I18 A549 24 755 Elongated +0.27787934186471663 5.385245463853716e-19 BR00116992 buparlisib final compound L12 A549 24 547 Elongated +0.3090909090909091 5.811024428997954e-19 BR00116991 RGB-286638 final compound K21 A549 24 440 Elongated +0.2788569373029476 9.728517286372185e-19 BR00116993 TG-02 final compound L21 A549 24 531 Elongated +0.3229306951206879 1.3582046710334634e-18 BR00116991 puromycin final compound C22 A549 24 392 Elongated +0.28992993077753554 1.811983032050079e-18 BR00116994 buparlisib final compound L12 A549 24 485 Elongated +0.32470490644038297 1.8876644046011298e-18 BR00116994 TG-101348 final compound M20 A549 24 384 Elongated +0.30374452263975565 1.890018379004937e-18 BR00116991 PHA-793887 final compound E13 A549 24 442 Elongated +0.35874320831891904 2.1878224500208732e-18 BR00116991 romidepsin final compound N19 A549 24 314 Elongated +0.2524421580978663 2.7106271698189633e-18 BR00116994 danusertib final compound E05 A549 24 633 Elongated +0.2452100270398101 3.784995921510254e-18 BR00116991 NVP-HSP990 final compound E23 A549 24 668 Elongated +0.26778535163749617 7.308633530572221e-18 BR00116994 PHA-793887 final compound E13 A549 24 553 Elongated +0.2509186673199412 7.926259975770652e-18 BR00116993 PHA-793887 final compound I06 A549 24 628 Elongated +0.28125399381438027 2.3719296220710667e-17 BR00116994 PHA-793887 final compound I06 A549 24 483 Elongated +0.2552023260284506 4.435320149558681e-17 BR00116992 buparlisib final compound D11 A549 24 578 Elongated +0.27058823529411763 7.880107933862791e-17 BR00116991 TG-02 final compound L21 A549 24 510 Elongated +0.24822553897180763 9.6574700373339e-17 BR00116994 UNC2025 final compound N06 A549 24 600 Elongated +0.269058330717693 1.1798314849276885e-16 BR00116991 buparlisib final compound D11 A549 24 507 Elongated +0.44044665012406947 1.3194899583785206e-16 BR00116991 ponatinib final compound C20 A549 24 182 Elongated +0.24666666666666667 1.9732682906849847e-16 BR00116992 danusertib final compound E05 A549 24 600 Elongated +0.2401263823064771 2.0256011897511027e-16 BR00116991 ganetespib final compound M10 A549 24 633 Elongated +0.23349511132053247 4.624530598959201e-16 BR00116993 ganetespib final compound I17 A549 24 650 Elongated +0.26055208192763857 5.305473159277353e-16 BR00116993 PHA-793887 final compound E13 A549 24 517 Elongated +0.32996669278996865 7.778084790820826e-16 BR00116991 CYT-997 final compound E06 A549 24 319 Elongated 0.5357374557452409 4.6596893780010884e-97 BR00116991 fludarabine-phosphate final compound N12 A549 24 735 Grape 0.5145604249667994 1.8635448708830975e-91 BR00116993 fludarabine-phosphate final compound N12 A549 24 753 Grape 0.5000133414613621 6.978267192939978e-80 BR00116992 fludarabine-phosphate final compound N12 A549 24 697 Grape @@ -59,6 +509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.27331719431635826 6.864489129209527e-59 BR00116993 LY2109761 final compound M02 A549 24 1777 Grape 0.3304487578388201 1.7021457166597669e-57 BR00116993 polydatin final compound K08 A549 24 1177 Grape 0.3912614205717654 5.073578754680623e-54 BR00116994 geldanamycin final compound L01 A549 24 780 Grape +0.40188514394029146 1.177083613387241e-53 BR00116991 geldanamycin final compound L01 A549 24 736 Grape +0.38816615403929444 1.3128497997796034e-48 BR00116994 ganetespib final compound M10 A549 24 712 Grape +0.3941657121038564 2.0290817503049418e-47 BR00116994 ganetespib final compound I17 A549 24 679 Grape +0.24889693753641193 1.8559790057462446e-46 BR00116994 LY2109761 final compound M02 A549 24 1690 Grape +0.3000745142514364 1.5061519521304045e-45 BR00116991 polydatin final compound K08 A549 24 1132 Grape +0.4523225241016652 1.5809517382894482e-45 BR00116992 CYT-997 final compound C09 A549 24 489 Grape +0.38528605977315117 6.983017637324982e-45 BR00116991 NVP-HSP990 final compound E23 A549 24 668 Grape +0.36752702030479806 2.1137528661780308e-44 BR00116992 ganetespib final compound I17 A549 24 729 Grape +0.3884768523972199 2.2295543225067056e-44 BR00116993 ganetespib final compound I17 A549 24 650 Grape +0.456645493767977 1.6600045458716763e-42 BR00116991 colchicine final compound K17 A549 24 447 Grape +0.3527872099603848 1.3895660478631095e-41 BR00116992 geldanamycin final compound L01 A549 24 741 Grape +0.44234484890640696 1.0234198844372344e-40 BR00116993 CYT-997 final compound E06 A549 24 456 Grape +0.26582557088393666 2.161630220705207e-40 BR00116992 PP-2 final compound J10 A549 24 1287 Grape +0.2532934724376752 7.527577682937893e-39 BR00116993 PP-2 final compound J10 A549 24 1364 Grape +0.23387622149837134 3.230618227931775e-37 BR00116994 PP-2 final compound J10 A549 24 1535 Grape +0.32821649384800755 1.709335291500607e-36 BR00116994 AZ191 final compound I18 A549 24 755 Grape +0.3570300157977883 3.181762873587364e-36 BR00116991 ganetespib final compound M10 A549 24 633 Grape +0.34424640297609277 5.3165326186975565e-36 BR00116993 aminopurvalanol-a final compound K03 A549 24 675 Grape +0.3216787344893481 1.0229139194989788e-35 BR00116994 aminopurvalanol-a final compound K03 A549 24 769 Grape +0.41511012125711455 2.080993425723235e-35 BR00116992 CYT-997 final compound E06 A549 24 450 Grape +0.38959127855464387 5.198449274153176e-35 BR00116993 CYT-997 final compound C09 A549 24 509 Grape +0.4430192599696316 6.312931061106297e-35 BR00116994 CYT-997 final compound C09 A549 24 388 Grape +0.4061936002815273 1.3623161514925622e-33 BR00116994 CYT-997 final compound E06 A549 24 447 Grape +0.4094327320147794 1.093678034812699e-32 BR00116991 oxibendazole final compound M19 A549 24 428 Grape +0.41686746987951806 1.1096321536861076e-32 BR00116994 colchicine final compound K17 A549 24 415 Grape +0.3753570755750695 1.432676352530436e-32 BR00116994 NVP-HSP990 final compound E23 A549 24 511 Grape +0.3522252703513649 6.341573775218096e-32 BR00116991 ganetespib final compound I17 A549 24 571 Grape +0.2971515737086584 3.1462414226841953e-31 BR00116991 NNC-55-0396 final compound A16 A549 24 791 Grape +0.24123539232053423 5.440034692124084e-31 BR00116991 PP-2 final compound J10 A549 24 1198 Grape +0.37390997132050374 6.043095710789572e-31 BR00116992 briciclib final compound H01 A549 24 490 Grape +0.3986013986013986 7.91210905086138e-31 BR00116992 colchicine final compound K17 A549 24 429 Grape +0.3084813740334493 9.171403450088154e-31 BR00116992 aminopurvalanol-a final compound K03 A549 24 723 Grape +0.37664223850766154 1.2519789342041541e-30 BR00116992 oxibendazole final compound M19 A549 24 475 Grape +0.38171189783078224 1.8243022184935107e-30 BR00116991 ixabepilone final compound J21 A549 24 463 Grape +0.3268200181383461 5.939022451606006e-30 BR00116992 ganetespib final compound M10 A549 24 622 Grape +0.34798534798534797 1.0118955127937056e-29 BR00116994 briciclib final compound H01 A549 24 546 Grape +0.3400352733686067 1.4652740575241353e-29 BR00116992 NVP-HSP990 final compound E23 A549 24 565 Grape +0.35805497438857226 4.820976516566939e-29 BR00116991 briciclib final compound H01 A549 24 498 Grape +0.31037291158592073 1.1484055646032463e-28 BR00116993 ganetespib final compound M10 A549 24 662 Grape +0.32011035756059436 1.302218144550103e-28 BR00116993 NVP-HSP990 final compound E23 A549 24 618 Grape +0.21320475405441483 1.9270233672894986e-27 BR00116991 LY2109761 final compound M02 A549 24 1357 Grape +0.2916503238842337 4.119220322836222e-27 BR00116992 AZ191 final compound I18 A549 24 710 Grape +0.1957680474916606 1.8777264938300798e-26 BR00116991 BQ-788 final compound E08 A549 24 1546 Grape +0.3178141785687765 5.164235023758298e-26 BR00116994 PF-03758309 final compound N21 A549 24 569 Grape +0.34695494001980154 2.256027588515291e-25 BR00116993 oxibendazole final compound M19 A549 24 465 Grape +0.28647298518404857 2.3204134401950976e-25 BR00116991 7-hydroxystaurosporine final compound L04 A549 24 684 Grape +0.30677966101694915 6.517720071976719e-25 BR00116993 PP-121 final compound B16 A549 24 590 Grape +0.35589233831057565 7.6359843798424e-25 BR00116991 KG-5 final compound C13 A549 24 433 Grape +0.25844435288193013 3.155390932426502e-24 BR00116991 AZ191 final compound I18 A549 24 809 Grape +0.3352909016356098 7.582783309129384e-24 BR00116993 briciclib final compound H01 A549 24 467 Grape +0.29081182221870844 1.4575546348387127e-23 BR00116992 PP-121 final compound B16 A549 24 615 Grape +0.2858803541089153 2.5571750455743012e-23 BR00116993 AZ191 final compound I18 A549 24 636 Grape +0.2637215528781794 3.0522020922453063e-23 BR00116991 SU3327 final compound I20 A549 24 747 Grape +0.36472660238619 3.3310541419711244e-23 BR00116993 ixabepilone final compound J21 A549 24 383 Grape +0.21048303850294092 4.067169501761637e-23 BR00116993 desonide final compound E16 A549 24 1167 Grape +0.2596954957310235 4.1181246351901803e-23 BR00116993 7-hydroxystaurosporine final compound L04 A549 24 764 Grape +0.3153904272600204 4.4468634053297856e-23 BR00116993 BI-2536 final compound E21 A549 24 514 Grape +0.33480176211453744 6.209166620727774e-23 BR00116993 KG-5 final compound C13 A549 24 454 Grape +0.18470152938916012 8.575339586046757e-23 BR00116991 PETCM final compound I04 A549 24 1492 Grape +0.2692510681075647 1.4029201273675727e-22 BR00116994 BMS-536924 final compound B15 A549 24 692 Grape +0.2987291864681241 1.5994189107261966e-22 BR00116991 BI-2536 final compound I14 A549 24 557 Grape +0.21846111943347404 2.1833960026521304e-22 BR00116991 ingenol-mebutate final compound M11 A549 24 1050 Grape +0.33985204316137363 2.429576522056557e-22 BR00116994 KG-5 final compound C13 A549 24 427 Grape +0.3246626686656672 4.593705584619239e-22 BR00116991 delanzomib final compound L11 A549 24 464 Grape +0.215311004784689 1.2773108402396323e-21 BR00116991 dexamethasone final compound A21 A549 24 1045 Grape +0.3243787956547772 1.3774434998474515e-20 BR00116992 KG-5 final compound C13 A549 24 432 Grape +0.19663884826063266 1.6467003012669753e-20 BR00116991 A-987306 final compound P20 A549 24 1180 Grape +0.2921357064978831 1.8651726782056362e-20 BR00116992 ixabepilone final compound J21 A549 24 531 Grape +0.2125375367784597 4.228651081882342e-20 BR00116991 fludarabine final compound B06 A549 24 994 Grape +0.3377654969909764 8.449834758626661e-20 BR00116993 colchicine final compound K17 A549 24 381 Grape +0.20185185185185187 1.1683092561796901e-19 BR00116993 PP-1 final compound A22 A549 24 1080 Grape +0.30603448275862066 1.3901210908201712e-19 BR00116994 ixabepilone final compound J21 A549 24 464 Grape +0.30511185168160576 2.479177534713124e-19 BR00116994 oxibendazole final compound M19 A549 24 458 Grape +0.2732049036777583 3.7224031911916593e-19 BR00116994 PP-121 final compound B16 A549 24 571 Grape +0.27271474189620715 1.4091249857653476e-18 BR00116994 PHA-793887 final compound E13 A549 24 553 Grape +0.2639593908629442 1.6587825001869275e-18 BR00116992 BI-2536 final compound I14 A549 24 591 Grape +0.23144204599754845 2.4737354494774497e-18 BR00116993 BMS-536924 final compound B15 A549 24 762 Grape +0.21632602137179247 3.0527072068248552e-18 BR00116994 NNC-55-0396 final compound A16 A549 24 869 Grape +0.2839476861167002 3.1032534806251196e-18 BR00116991 PF-03758309 final compound N21 A549 24 497 Grape +0.23726516276548099 4.15324735928828e-18 BR00116994 7-hydroxystaurosporine final compound L04 A549 24 711 Grape +0.23297074039262436 8.848719444567147e-18 BR00116991 GSK1070916 final compound C04 A549 24 724 Grape +0.269404933690648 1.1551406934706268e-17 BR00116992 PF-03758309 final compound N21 A549 24 539 Grape +0.27001862197392923 1.2611290033231205e-17 BR00116993 PF-03758309 final compound N21 A549 24 537 Grape +0.1811745545527807 1.391433132864791e-17 BR00116991 desonide final compound E16 A549 24 1194 Grape +0.253969878969879 2.7055926176532357e-17 BR00116991 BI-2536 final compound E21 A549 24 594 Grape +0.3548234018032676 2.8915788535167264e-17 BR00116992 NSC-632839 final compound M16 A549 24 298 Grape +0.20147679324894516 3.0375986143463104e-17 BR00116993 ingenol-mebutate final compound M11 A549 24 948 Grape +0.25582002014968336 3.6821939921623004e-17 BR00116994 BI-2536 final compound E21 A549 24 576 Grape +0.2487657810439043 3.7164826398029154e-17 BR00116994 TG-02 final compound L21 A549 24 610 Grape +0.17692070665571077 4.374205005780999e-17 BR00116992 ingenol-mebutate final compound M11 A549 24 1217 Grape 0.6059346815649337 8.451685955010109e-152 BR00116992 AMG900 final compound N09 A549 24 882 Hole 0.46739137655757634 2.422833981819571e-133 BR00116992 polydatin final compound K08 A549 24 1346 Hole 0.5887035656896319 1.3285729869145246e-128 BR00116994 AMG900 final compound N09 A549 24 798 Hole @@ -69,6 +609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.46712703039619086 2.669202521691128e-112 BR00116991 polydatin final compound K08 A549 24 1132 Hole 0.4570158923827207 1.795375216052805e-111 BR00116993 polydatin final compound K08 A549 24 1177 Hole 0.5594125500667557 2.974485088854783e-108 BR00116992 PF-431396 final compound L20 A549 24 749 Hole +0.5148467851062901 2.5849730381938686e-90 BR00116994 PF-431396 final compound L20 A549 24 744 Hole +0.5368222473857213 6.749341590139317e-88 BR00116993 PF-431396 final compound L20 A549 24 659 Hole +0.5316132020280812 2.479151400073425e-83 BR00116991 danusertib final compound N18 A549 24 641 Hole +0.528573544294424 9.569603039482483e-82 BR00116993 danusertib final compound E05 A549 24 638 Hole +0.5239699653446284 2.1129734903697457e-80 BR00116994 danusertib final compound N18 A549 24 636 Hole +0.4755552763468331 5.749330058363923e-78 BR00116993 danusertib final compound N18 A549 24 758 Hole +0.48375041303647687 7.122012012019244e-74 BR00116993 GSK1070916 final compound C04 A549 24 694 Hole +0.5050917871497991 8.076653002478005e-74 BR00116994 danusertib final compound E05 A549 24 633 Hole +0.4671233796762711 1.3602396458724443e-70 BR00116994 GSK1070916 final compound C04 A549 24 709 Hole +0.29074446134287685 1.7281894334206254e-68 BR00116992 LY2109761 final compound M02 A549 24 1822 Hole +0.4809393524851801 5.274880332824286e-68 BR00116994 BI-2536 final compound I14 A549 24 645 Hole +0.46264447575561746 8.079199610947271e-67 BR00116992 GSK1070916 final compound C04 A549 24 685 Hole +0.4905070439607059 1.7374782441782935e-66 BR00116992 danusertib final compound N18 A549 24 603 Hole +0.45769727348674716 4.4015559849372305e-60 BR00116993 BI-2536 final compound I14 A549 24 630 Hole +0.27380655259272896 4.364953722295689e-59 BR00116993 LY2109761 final compound M02 A549 24 1777 Hole +0.27327521461110293 4.996065910561912e-56 BR00116994 LY2109761 final compound M02 A549 24 1690 Hole +0.4538060788060788 9.242129345138734e-56 BR00116991 BI-2536 final compound E21 A549 24 594 Hole +0.4630132777772444 1.496600978375474e-54 BR00116991 BI-2536 final compound I14 A549 24 557 Hole +0.44666666666666666 3.0050900590005045e-54 BR00116992 danusertib final compound E05 A549 24 600 Hole +0.43423137876386686 8.201784139594708e-54 BR00116991 danusertib final compound E05 A549 24 631 Hole +0.4563726824921409 8.813403735972666e-54 BR00116992 BI-2536 final compound E21 A549 24 568 Hole +0.4043962006067414 1.2963123268161765e-53 BR00116991 GSK1070916 final compound C04 A549 24 724 Hole +0.44746689694876224 1.670525464769373e-52 BR00116994 BI-2536 final compound E21 A549 24 576 Hole +0.3818498870223008 3.110995960929647e-51 BR00116994 geldanamycin final compound L01 A549 24 780 Hole +0.43316412859560066 3.5914396614559036e-50 BR00116992 BI-2536 final compound I14 A549 24 591 Hole +0.40601012575534867 8.772783950903912e-47 BR00116993 PHA-793887 final compound I06 A549 24 628 Hole +0.4440670922896755 4.4334826660054845e-46 BR00116993 BI-2536 final compound E21 A549 24 514 Hole +0.28477598062535137 7.145621322284373e-44 BR00116992 ingenol-mebutate final compound M11 A549 24 1217 Hole +0.3787056184692817 1.0278550032259372e-43 BR00116993 aminopurvalanol-a final compound K03 A549 24 675 Hole +0.3681658401858013 1.6258944529686505e-43 BR00116994 ganetespib final compound M10 A549 24 712 Hole +0.41470546729109986 6.0650395071651505e-43 BR00116994 PHA-793887 final compound E13 A549 24 553 Hole +0.35067861473876666 1.4207629908676496e-42 BR00116994 aminopurvalanol-a final compound K03 A549 24 769 Hole +0.2910899269145218 1.0651937705397024e-39 BR00116991 ingenol-mebutate final compound M11 A549 24 1050 Hole +0.4056610138995097 1.274299108471155e-38 BR00116993 PHA-793887 final compound E13 A549 24 517 Hole +0.2369005319313515 1.703904493923782e-38 BR00116991 BQ-788 final compound E08 A549 24 1546 Hole +0.36659482638287894 3.474069614612098e-36 BR00116992 PHA-793887 final compound I06 A549 24 598 Hole +0.33144080520491576 3.82618957928381e-36 BR00116991 fludarabine-phosphate final compound N12 A549 24 735 Hole +0.3133809147130735 5.312666465273723e-36 BR00116994 fludarabine-phosphate final compound N12 A549 24 816 Hole +0.3428232952872199 2.0220720746021732e-35 BR00116991 NVP-HSP990 final compound E23 A549 24 668 Hole +0.2762271414821944 2.734247917168571e-35 BR00116994 ingenol-mebutate final compound M11 A549 24 1039 Hole +0.3457886676875957 5.194483690837095e-35 BR00116993 ganetespib final compound I17 A549 24 650 Hole +0.38048204722048146 1.741733456650575e-33 BR00116994 NVP-HSP990 final compound E23 A549 24 511 Hole +0.31444355909694555 2.7250311666746732e-33 BR00116993 fludarabine-phosphate final compound N12 A549 24 753 Hole +0.3426303283976649 8.385327414497246e-33 BR00116993 NVP-HSP990 final compound E23 A549 24 618 Hole +0.34373738189453285 1.8049084443117345e-32 BR00116994 TG-02 final compound L21 A549 24 610 Hole +0.3235411552937326 6.979223067679438e-32 BR00116994 ganetespib final compound I17 A549 24 679 Hole +0.2742616033755274 8.890166748985143e-32 BR00116993 ingenol-mebutate final compound M11 A549 24 948 Hole +0.37575757575757573 1.6705210309818864e-31 BR00116992 PHA-793887 final compound E13 A549 24 495 Hole +0.34110609067747705 2.411178661321913e-31 BR00116993 epothilone-b final compound F07 A549 24 597 Hole +0.3059564233163554 3.6146468510054105e-31 BR00116992 geldanamycin final compound L01 A549 24 741 Hole +0.3020239043824701 8.681860195624744e-31 BR00116993 azeliragon final compound C08 A549 24 753 Hole +0.37862240585970514 4.183658118799237e-30 BR00116991 ixabepilone final compound J21 A549 24 463 Hole +0.3365006769971416 1.8341133765181613e-29 BR00116994 epothilone-b final compound F07 A549 24 575 Hole +0.3806727066586315 5.374226558301406e-29 BR00116991 PHA-793887 final compound E13 A549 24 442 Hole +0.29653254946096436 5.660692232779646e-29 BR00116991 geldanamycin final compound L01 A549 24 736 Hole +0.32761749761607145 7.407055594069384e-29 BR00116991 UNC2025 final compound N06 A549 24 597 Hole +0.34503985953584526 1.7367419504906542e-28 BR00116992 ixabepilone final compound J21 A549 24 531 Hole +0.3442730485198586 1.8933139307145793e-28 BR00116993 TG-02 final compound L21 A549 24 531 Hole +0.33372352546393846 2.3166747844263513e-28 BR00116992 NVP-HSP990 final compound E23 A549 24 565 Hole +0.35824195486031235 3.4119182901779454e-28 BR00116994 PHA-793887 final compound I06 A549 24 483 Hole +0.30757925963673427 3.7541544750669264e-28 BR00116993 ganetespib final compound M10 A549 24 662 Hole +0.3127962085308057 9.315271260521154e-28 BR00116991 ganetespib final compound M10 A549 24 633 Hole +0.35745058849655786 1.3234274226000497e-27 BR00116992 oxibendazole final compound M19 A549 24 475 Hole +0.28633043910821687 6.1304060691087516e-27 BR00116992 ganetespib final compound I17 A549 24 729 Hole +0.31929008143765936 3.5606061940648055e-26 BR00116994 PF-03758309 final compound N21 A549 24 569 Hole +0.2777777777777778 4.449658332723204e-26 BR00116994 azeliragon final compound C08 A549 24 756 Hole +0.3222520983733437 1.42543443238525e-25 BR00116993 anisomycin final compound N03 A549 24 547 Hole +0.22074281393877174 3.3840553407828965e-25 BR00116991 AC-710 final compound I03 A549 24 1154 Hole +0.2562185981385388 3.5285865903167248e-25 BR00116992 azeliragon final compound C08 A549 24 855 Hole +0.27631888178704483 1.0200948691431257e-24 BR00116992 aminopurvalanol-a final compound K03 A549 24 723 Hole +0.3560965007607042 1.2678047891456273e-24 BR00116991 oxibendazole final compound M19 A549 24 428 Hole +0.3049887021607118 2.1684660800405848e-24 BR00116993 UNC2025 final compound N06 A549 24 582 Hole +0.2999336650082919 2.372502457641741e-24 BR00116994 UNC2025 final compound N06 A549 24 600 Hole +0.231558954879113 3.4607481401249594e-23 BR00116991 azeliragon final compound C08 A549 24 968 Hole +0.3156862745098039 7.387628810512275e-23 BR00116991 TG-02 final compound L21 A549 24 510 Hole +0.1739079770012281 7.568312773751156e-23 BR00116994 CC-401 final compound M09 A549 24 1696 Hole +0.18178040944771456 2.3606856877760094e-22 BR00116993 filgotinib final compound H07 A549 24 1511 Hole +0.19106514738936164 4.284813843551675e-22 BR00116991 LY2109761 final compound M02 A549 24 1357 Hole +0.3081395348837209 4.949613101535658e-22 BR00116992 TG-02 final compound L21 A549 24 516 Hole +0.297433763663353 8.744906954606343e-21 BR00116992 epothilone-b final compound F07 A549 24 517 Hole +0.18009757911787302 1.0761632252962444e-20 BR00116994 AC-710 final compound I03 A549 24 1430 Hole +0.18474675629631016 1.3676487087958237e-20 BR00116992 AC-710 final compound I03 A549 24 1351 Hole +0.2849137696534465 1.510839468361105e-20 BR00116993 homoharringtonine final compound N15 A549 24 561 Hole +0.2807184059373201 2.89658214961759e-20 BR00116991 ganetespib final compound I17 A549 24 571 Hole +0.2886405959031657 4.080075007728845e-20 BR00116993 PF-03758309 final compound N21 A549 24 537 Hole +0.2523609255279627 4.2538096356370596e-20 BR00116992 fludarabine-phosphate final compound N12 A549 24 697 Hole +0.16531359185945912 4.271665336060438e-20 BR00116991 CC-401 final compound M09 A549 24 1643 Hole +0.308641293085584 4.6774425723885007e-20 BR00116993 oxibendazole final compound M19 A549 24 465 Hole +0.3081896551724138 7.374283216541929e-20 BR00116994 ixabepilone final compound J21 A549 24 464 Hole +0.1778243411477968 9.635230891824974e-20 BR00116991 RKI-1447 final compound J04 A549 24 1394 Hole 0.539261885411984 1.4100172377532111e-179 BR00116992 polydatin final compound K08 A549 24 1346 Interphase 0.504508021728645 1.8122286967157768e-165 BR00116994 polydatin final compound K08 A549 24 1421 Interphase 0.5276147325574787 1.0476786837800973e-150 BR00116993 polydatin final compound K08 A549 24 1177 Interphase @@ -79,6 +709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5398661424940415 1.6965477791363556e-101 BR00116991 AMG900 final compound N09 A549 24 753 Interphase 0.33174600312594604 4.634824788345275e-87 BR00116993 LY2109761 final compound M02 A549 24 1777 Interphase 0.32145218818624766 7.753961186170783e-84 BR00116992 LY2109761 final compound M02 A549 24 1822 Interphase +0.45794392523364486 3.3510739821616094e-71 BR00116992 PF-431396 final compound L20 A549 24 749 Interphase +0.4508380985638832 2.378030508813807e-68 BR00116994 PF-431396 final compound L20 A549 24 744 Interphase +0.4476584022038568 7.314647048792511e-66 BR00116991 PF-431396 final compound L20 A549 24 726 Interphase +0.29513360988860576 2.0237818380379475e-65 BR00116994 LY2109761 final compound M02 A549 24 1690 Interphase +0.45081833505519003 5.785683250330906e-64 BR00116993 GSK1070916 final compound C04 A549 24 694 Interphase +0.4593222359246134 2.7083546865554386e-63 BR00116993 PF-431396 final compound L20 A549 24 659 Interphase +0.4488880112556463 1.9267283689719444e-58 BR00116993 danusertib final compound E05 A549 24 638 Interphase +0.4253732522628233 2.2539007412045336e-58 BR00116994 GSK1070916 final compound C04 A549 24 709 Interphase +0.42074941997817633 4.311906976464006e-55 BR00116992 GSK1070916 final compound C04 A549 24 685 Interphase +0.4298149614803082 6.321601732008981e-54 BR00116994 BI-2536 final compound I14 A549 24 645 Interphase +0.41657417961485393 1.2694968268168348e-49 BR00116994 danusertib final compound E05 A549 24 633 Interphase +0.3802752998003658 3.3576890491801328e-49 BR00116993 danusertib final compound N18 A549 24 758 Interphase +0.40843776106934004 1.4332095555701813e-47 BR00116993 BI-2536 final compound I14 A549 24 630 Interphase +0.4030192628575378 7.995583366815641e-47 BR00116994 danusertib final compound N18 A549 24 636 Interphase +0.2846175009599134 2.0540396318011277e-46 BR00116992 PP-2 final compound J10 A549 24 1287 Interphase +0.4004217043681747 2.557067317970879e-46 BR00116991 danusertib final compound N18 A549 24 641 Interphase +0.4090758830432555 1.5455442639520762e-45 BR00116992 danusertib final compound N18 A549 24 603 Interphase +0.2551769438992634 7.896168414036587e-45 BR00116991 BQ-788 final compound E08 A549 24 1546 Interphase +0.3669944904212803 6.30434675204711e-44 BR00116991 GSK1070916 final compound C04 A549 24 724 Interphase +0.393026941362916 6.968580481170462e-44 BR00116991 danusertib final compound E05 A549 24 631 Interphase +0.2673215242381929 2.491375764728972e-43 BR00116993 PP-2 final compound J10 A549 24 1364 Interphase +0.38164736266487465 1.228189562305432e-40 BR00116992 PP-121 final compound B16 A549 24 615 Interphase +0.23843648208469057 1.1124885150598662e-38 BR00116994 PP-2 final compound J10 A549 24 1535 Interphase +0.3790802753262109 1.3404445405817573e-38 BR00116993 epothilone-b final compound F07 A549 24 597 Interphase +0.3326643799382242 3.722455876323175e-38 BR00116992 KU-60019 final compound I07 A549 24 765 Interphase +0.37796610169491524 6.364991740336396e-38 BR00116993 PP-121 final compound B16 A549 24 590 Interphase +0.37166666666666665 2.8842863268684734e-37 BR00116992 danusertib final compound E05 A549 24 600 Interphase +0.37055837563451777 1.716514501644678e-36 BR00116992 BI-2536 final compound I14 A549 24 591 Interphase +0.37210470889122915 4.5901884453110506e-36 BR00116994 epothilone-b final compound F07 A549 24 575 Interphase +0.36447811447811446 1.1162632905209424e-35 BR00116991 BI-2536 final compound E21 A549 24 594 Interphase +0.38132407289409964 4.147566022781233e-35 BR00116992 ixabepilone final compound J21 A549 24 531 Interphase +0.3883510188750117 1.5878935961863296e-31 BR00116991 ixabepilone final compound J21 A549 24 463 Interphase +0.34914230550261144 3.110636205122473e-31 BR00116992 BI-2536 final compound E21 A549 24 568 Interphase +0.3647234342434738 5.672549886363545e-31 BR00116992 epothilone-b final compound F07 A549 24 517 Interphase +0.3467600700525394 7.62987173578659e-31 BR00116994 PP-121 final compound B16 A549 24 571 Interphase +0.24040066777963273 8.889375370536828e-31 BR00116991 PP-2 final compound J10 A549 24 1198 Interphase +0.35841864682104946 8.820960620750854e-30 BR00116993 BI-2536 final compound E21 A549 24 514 Interphase +0.33801093839953944 1.0213564524403555e-29 BR00116994 BI-2536 final compound E21 A549 24 576 Interphase +0.236168229659583 2.4514400925606556e-29 BR00116991 A-987306 final compound P20 A549 24 1180 Interphase +0.3054368769372539 5.0062617538911686e-29 BR00116994 BMS-536924 final compound B15 A549 24 692 Interphase +0.24880382775119617 8.38591363930883e-29 BR00116991 dexamethasone final compound A21 A549 24 1045 Interphase +0.36675930566312814 1.2381304842955295e-28 BR00116993 briciclib final compound H01 A549 24 467 Interphase +0.33610793754420326 1.8432287077744831e-28 BR00116991 BI-2536 final compound I14 A549 24 557 Interphase +0.336996336996337 7.300714267199801e-28 BR00116994 briciclib final compound H01 A549 24 546 Interphase +0.2716616413410156 4.901101494459624e-27 BR00116994 KU-60019 final compound I07 A549 24 817 Interphase +0.35082389518099044 2.2805372665494455e-26 BR00116992 oxibendazole final compound M19 A549 24 475 Interphase +0.38910932478087756 2.6017051031242116e-26 BR00116993 ixabepilone final compound J21 A549 24 383 Interphase +0.35129310344827586 8.375903731737849e-26 BR00116994 ixabepilone final compound J21 A549 24 464 Interphase +0.20343153625069044 2.701985388671885e-25 BR00116991 NVS-PAK1-1 final compound N14 A549 24 1374 Interphase +0.3151889127206732 1.0477639221084513e-24 BR00116991 PP-121 final compound B16 A549 24 550 Interphase +0.2631181656382662 1.2496870040839725e-23 BR00116993 BMS-536924 final compound B15 A549 24 762 Interphase +0.32332599027390996 2.48540408766612e-23 BR00116992 briciclib final compound H01 A549 24 490 Interphase +0.3215094155923182 3.0058794043092337e-23 BR00116991 epothilone-b final compound F07 A549 24 494 Interphase +0.21004464269267864 5.728099382729653e-23 BR00116993 desonide final compound E16 A549 24 1167 Interphase +0.33202137439669044 8.853266698027069e-23 BR00116994 oxibendazole final compound M19 A549 24 458 Interphase +0.26864385018891457 1.0307727989462736e-22 BR00116993 KU-60019 final compound I07 A549 24 702 Interphase +0.32440422739517855 2.5609092683508777e-22 BR00116993 oxibendazole final compound M19 A549 24 465 Interphase +0.3290922791560399 2.776119541785854e-22 BR00116993 CYT-997 final compound E06 A549 24 456 Interphase +0.33625298848076507 4.170103895294881e-22 BR00116991 oxibendazole final compound M19 A549 24 428 Interphase +0.2020830432599606 8.37679475085028e-22 BR00116991 desonide final compound E16 A549 24 1194 Interphase +0.27081957590432165 1.6726819230682601e-21 BR00116992 BMS-536924 final compound B15 A549 24 651 Interphase +0.18813157760502192 1.9849049603323944e-21 BR00116991 LY2109761 final compound M02 A549 24 1357 Interphase +0.3389830508474576 2.0084259269302356e-21 BR00116992 TG-101348 final compound M20 A549 24 413 Interphase +0.3520038227411547 2.292114192081348e-21 BR00116993 colchicine final compound K17 A549 24 381 Interphase +0.3807014106583072 2.5540956993478344e-21 BR00116993 TG-101348 final compound M20 A549 24 319 Interphase +0.2319735630315835 3.0829419245871473e-21 BR00116993 dexamethasone final compound A21 A549 24 882 Interphase +0.2776123242813959 8.342404614797518e-21 BR00116991 UNC2025 final compound N06 A549 24 597 Interphase +0.2874271073806696 2.2990660491771892e-20 BR00116993 anisomycin final compound N03 A549 24 547 Interphase +0.2756731629242574 5.702262947886668e-20 BR00116993 UNC2025 final compound N06 A549 24 582 Interphase +0.2962268234615107 7.19118428330973e-20 BR00116991 briciclib final compound H01 A549 24 498 Interphase +0.33723618363794605 9.070195655902421e-20 BR00116994 TG-101348 final compound M20 A549 24 384 Interphase +0.29531298848086956 9.955240358748086e-20 BR00116991 anisomycin final compound N03 A549 24 498 Interphase +0.3098234260147012 1.3170234507638834e-19 BR00116991 colchicine final compound K17 A549 24 447 Interphase +0.3228915662650602 1.5600759214448026e-19 BR00116994 colchicine final compound K17 A549 24 415 Interphase +0.18465154435531772 2.0040333506103447e-19 BR00116991 loperamide final compound P23 A549 24 1269 Interphase +0.1598135536451937 2.4068994661339173e-19 BR00116994 CC-401 final compound M09 A549 24 1696 Interphase +0.3080970056916605 2.4550173676321414e-19 BR00116992 CYT-997 final compound E06 A549 24 450 Interphase +0.16327064939036043 2.711423190696995e-19 BR00116992 CC-401 final compound M09 A549 24 1620 Interphase +0.2809611829944547 3.309700683879214e-19 BR00116992 anisomycin final compound N03 A549 24 541 Interphase +0.20006360139816778 3.7347264034581645e-19 BR00116991 dexamethasone final compound O02 A549 24 1063 Interphase +0.19907407407407407 3.952181145153106e-19 BR00116993 PP-1 final compound A22 A549 24 1080 Interphase +0.6997854431424327 8.080920463991707e-19 BR00116993 zaprinast final compound O01 A549 24 83 Interphase +0.1993835398792501 1.059530966751223e-18 BR00116991 ingenol-mebutate final compound M11 A549 24 1050 Interphase +0.3315508021390374 1.3459737922636252e-18 BR00116991 LDN-212854 final compound K01 A549 24 374 Interphase +0.26717806430553287 4.3288179770894826e-18 BR00116993 homoharringtonine final compound N15 A549 24 561 Interphase +0.18378806021211083 5.051245530791065e-18 BR00116994 desonide final compound E16 A549 24 1184 Interphase +0.1882145998240985 5.147658426964035e-18 BR00116991 GNF-5837 final compound A10 A549 24 1137 Interphase +0.2812653895914194 1.1637492870757558e-17 BR00116992 CYT-997 final compound C09 A549 24 489 Interphase +0.20479565779981448 1.394159319710166e-17 BR00116991 DDR1-IN-1 final compound A23 A549 24 935 Interphase +0.29836829836829837 3.01826774930819e-17 BR00116992 colchicine final compound K17 A549 24 429 Interphase 0.6754344886526608 0.0 BR00116991 BQ-788 final compound E08 A549 24 1546 Large 0.5848540145985401 5.360004812500506e-174 BR00116991 quinine final compound A05 A549 24 1096 Large 0.5301458603001102 8.143262240048109e-106 BR00116994 fludarabine-phosphate final compound N12 A549 24 816 Large @@ -89,6 +809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5013774104683195 2.4914580093727868e-83 BR00116991 PF-431396 final compound L20 A549 24 726 Large 0.40006027528217397 6.863527049945169e-83 BR00116991 AC-710 final compound I03 A549 24 1154 Large 0.48731642189586116 5.252229231212566e-81 BR00116992 PF-431396 final compound L20 A549 24 749 Large +0.4703703703703704 7.548746308150966e-79 BR00116994 geldanamycin final compound L01 A549 24 780 Large +0.4678318623385855 4.2265974488775507e-73 BR00116991 geldanamycin final compound L01 A549 24 736 Large +0.48361945401827233 4.752656767754126e-72 BR00116993 aminopurvalanol-a final compound K03 A549 24 675 Large +0.4534768466166883 8.086445695198903e-71 BR00116993 danusertib final compound N18 A549 24 758 Large +0.46428337513532675 1.1342164029414252e-70 BR00116992 aminopurvalanol-a final compound K03 A549 24 723 Large +0.4679828123187306 1.0905462676592779e-66 BR00116991 NVP-HSP990 final compound E23 A549 24 668 Large +0.47567277691107646 2.6619667241816706e-66 BR00116991 danusertib final compound N18 A549 24 641 Large +0.43379226478708854 1.179133662648354e-65 BR00116994 aminopurvalanol-a final compound K03 A549 24 769 Large +0.4454487556339408 1.2563020109693167e-65 BR00116992 ganetespib final compound I17 A549 24 729 Large +0.47192519968800295 1.6645854391111006e-64 BR00116994 danusertib final compound N18 A549 24 636 Large +0.4645046530804571 3.564587852853629e-64 BR00116993 ganetespib final compound I17 A549 24 650 Large +0.3970357373718718 1.0903365023587636e-62 BR00116992 AMG900 final compound N09 A549 24 882 Large +0.4393085807545038 1.896605228395966e-62 BR00116994 ganetespib final compound M10 A549 24 712 Large +0.46300832925036745 4.992940259948031e-61 BR00116993 PHA-793887 final compound I06 A549 24 628 Large +0.48403489878416134 1.527898908794771e-60 BR00116992 NVP-HSP990 final compound E23 A549 24 565 Large +0.4549763033175355 1.9849709902453313e-59 BR00116991 ganetespib final compound M10 A549 24 633 Large +0.4575434014864768 1.335425771974921e-57 BR00116992 danusertib final compound N18 A549 24 603 Large +0.4768184100583191 1.6397215016455275e-57 BR00116994 PHA-793887 final compound E13 A549 24 553 Large +0.4136465543511384 2.1668576599271296e-57 BR00116992 geldanamycin final compound L01 A549 24 741 Large +0.2924756998252794 7.601096990121896e-57 BR00116991 PETCM final compound I04 A549 24 1492 Large +0.45666666666666667 8.777193203712736e-57 BR00116992 danusertib final compound E05 A549 24 600 Large +0.4269219440353461 6.482428289056962e-56 BR00116994 ganetespib final compound I17 A549 24 679 Large +0.6537267080745341 8.049257871761374e-56 BR00116991 AR-12 final compound C10 A549 24 273 Large +0.4783909203803167 2.557525705356285e-53 BR00116994 NVP-HSP990 final compound E23 A549 24 511 Large +0.3845797052229067 3.056036916390297e-53 BR00116994 AMG900 final compound N09 A549 24 798 Large +0.4529196267234337 5.220493056752848e-53 BR00116994 PF-03758309 final compound N21 A549 24 569 Large +0.6691358024691358 4.401570298657414e-52 BR00116993 AR-12 final compound C10 A549 24 240 Large +0.3881339982234418 3.65446088961015e-51 BR00116991 AMG900 final compound N09 A549 24 753 Large +0.29237371645965415 3.959334409445229e-51 BR00116992 polydatin final compound K08 A549 24 1346 Large +0.4129508972445674 4.5587219135617835e-51 BR00116993 ganetespib final compound M10 A549 24 662 Large +0.39042879799787567 5.770826570732573e-51 BR00116994 PF-431396 final compound L20 A549 24 744 Large +0.4707070707070707 6.136796434692266e-50 BR00116992 PHA-793887 final compound E13 A549 24 495 Large +0.4218475450163386 9.553172255928376e-50 BR00116993 NVP-HSP990 final compound E23 A549 24 618 Large +0.3272377285851781 1.2707361606784198e-49 BR00116994 ingenol-mebutate final compound M11 A549 24 1039 Large +0.41877937175364827 2.2195730933415206e-49 BR00116992 ganetespib final compound M10 A549 24 622 Large +0.27893199123895973 2.7018512342583577e-49 BR00116994 polydatin final compound K08 A549 24 1421 Large +0.2667476327570404 4.443702396041854e-49 BR00116993 AC-710 final compound I03 A549 24 1556 Large +0.4914251861536419 6.853759978511116e-49 BR00116991 PHA-793887 final compound E13 A549 24 442 Large +0.41213730077789107 8.912319072410745e-49 BR00116994 danusertib final compound E05 A549 24 633 Large +0.45412187186061503 9.522085549973353e-49 BR00116993 PHA-793887 final compound E13 A549 24 517 Large +0.40852072174363785 4.490261632339163e-48 BR00116993 danusertib final compound E05 A549 24 638 Large +0.4420497491926063 6.968305031316236e-48 BR00116992 PF-03758309 final compound N21 A549 24 539 Large +0.4159035236480121 1.0307588860263007e-47 BR00116994 TG-02 final compound L21 A549 24 610 Large +0.3309207261776432 2.1511272454024226e-47 BR00116991 azeliragon final compound C08 A549 24 968 Large +0.4613270965927971 4.411307194676453e-47 BR00116994 PHA-793887 final compound I06 A549 24 483 Large +0.3921280526660829 7.001615289451025e-46 BR00116993 PF-431396 final compound L20 A549 24 659 Large +0.3792903170585574 1.5359777886062935e-45 BR00116993 KU-60019 final compound I07 A549 24 702 Large +0.36088190093391653 3.524356280466833e-45 BR00116993 AMG900 final compound N09 A549 24 770 Large +0.4301675977653631 5.618775840090626e-45 BR00116993 PF-03758309 final compound N21 A549 24 537 Large +0.40847457627118644 2.0487698636790737e-44 BR00116993 PP-121 final compound B16 A549 24 590 Large +0.3975016800411116 6.653112124638296e-44 BR00116992 PP-121 final compound B16 A549 24 615 Large +0.4017090915181936 1.4346903635999017e-43 BR00116992 PHA-793887 final compound I06 A549 24 598 Large +0.4102574308353643 1.828381170921661e-43 BR00116991 ganetespib final compound I17 A549 24 571 Large +0.5939224897240164 2.5635484477922844e-43 BR00116994 AR-12 final compound C10 A549 24 260 Large +0.35185185185185186 6.3063032831485e-42 BR00116994 azeliragon final compound C08 A549 24 756 Large +0.2549178603062438 3.176019757602146e-41 BR00116994 AC-710 final compound I03 A549 24 1430 Large +0.273262146996497 2.185722888234531e-40 BR00116992 ingenol-mebutate final compound M11 A549 24 1217 Large +0.41472868217054265 4.061561882954216e-40 BR00116992 TG-02 final compound L21 A549 24 516 Large +0.4065998010960875 6.465717599235685e-40 BR00116993 TG-02 final compound L21 A549 24 531 Large +0.6130689001264222 7.041376753837811e-40 BR00116992 AR-12 final compound C10 A549 24 224 Large +0.4127951342979109 1.1474155198271024e-39 BR00116993 BI-2536 final compound E21 A549 24 514 Large +0.4329138886280402 1.6942882378585116e-39 BR00116991 ixabepilone final compound J21 A549 24 463 Large +0.3924448839434582 5.045308858752238e-39 BR00116991 BI-2536 final compound I14 A549 24 557 Large +0.24141755680906254 8.897158535264293e-39 BR00116991 diltiazem final compound O04 A549 24 1493 Large +0.269895693423988 2.424574868858772e-38 BR00116993 polydatin final compound K08 A549 24 1177 Large +0.3509158518110453 4.090431618784737e-38 BR00116992 GSK1070916 final compound C04 A549 24 685 Large +0.3959191764722541 1.301824256957281e-37 BR00116992 ixabepilone final compound J21 A549 24 531 Large +0.33342895086321384 1.4269104816490238e-37 BR00116993 azeliragon final compound C08 A549 24 753 Large +0.24767961215235426 7.996989677020623e-37 BR00116992 AC-710 final compound I03 A549 24 1351 Large +0.31565364062453355 1.700279352501355e-36 BR00116994 KU-60019 final compound I07 A549 24 817 Large +0.37055837563451777 1.716514501644678e-36 BR00116992 BI-2536 final compound I14 A549 24 591 Large +0.396078431372549 4.171208291113869e-36 BR00116991 TG-02 final compound L21 A549 24 510 Large +0.34604603163174696 1.0348606778079874e-34 BR00116994 BI-2536 final compound I14 A549 24 645 Large +0.3882857142857143 4.192182700162539e-34 BR00116991 PF-03758309 final compound N21 A549 24 497 Large +0.31537739551869487 4.5698323643911605e-34 BR00116992 KU-60019 final compound I07 A549 24 765 Large +0.41407302760269504 1.8956112019624674e-33 BR00116991 oxibendazole final compound M19 A549 24 428 Large +0.29360019767729184 5.322634552020729e-33 BR00116992 azeliragon final compound C08 A549 24 855 Large +0.39655172413793105 5.780770450542095e-33 BR00116994 ixabepilone final compound J21 A549 24 464 Large +0.29714720855562743 4.6219789366810887e-32 BR00116993 JTE-607 final compound C14 A549 24 808 Large +0.3502626970227671 1.7832979307878181e-31 BR00116994 PP-121 final compound B16 A549 24 571 Large +0.38599617784531787 2.131639214279852e-31 BR00116993 oxibendazole final compound M19 A549 24 465 Large +0.2649818509044215 2.978707637090449e-31 BR00116991 fludarabine final compound B06 A549 24 994 Large +0.2574034108128461 6.298745395487898e-31 BR00116993 fludarabine final compound B06 A549 24 1042 Large +0.3111653688273617 6.32340200970325e-31 BR00116994 GSK1070916 final compound C04 A549 24 709 Large +0.32701421800947866 2.3965304027573994e-30 BR00116991 aminopurvalanol-a final compound K03 A549 24 633 Large +0.25610751259853193 5.7488010261987504e-30 BR00116994 fludarabine final compound B06 A549 24 1019 Large +0.4197860962566845 6.517613103769086e-30 BR00116991 LDN-212854 final compound K01 A549 24 374 Large +0.38927738927738925 2.2046057794471134e-29 BR00116992 colchicine final compound K17 A549 24 429 Large +0.40871555546418314 3.1721100261407223e-29 BR00116993 ixabepilone final compound J21 A549 24 383 Large +0.2321922215502219 7.059385559331818e-29 BR00116991 arcyriaflavin-a final compound B04 A549 24 1204 Large 0.64049955396967 6.577942493446171e-103 BR00116992 ixabepilone final compound J21 A549 24 531 Metaphase 0.6410324618645828 3.606445905271859e-95 BR00116992 briciclib final compound H01 A549 24 490 Metaphase 0.651577612921401 2.6865136015817607e-93 BR00116991 ixabepilone final compound J21 A549 24 463 Metaphase @@ -99,6 +909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.3553616689983785 2.151163172443206e-87 BR00116991 BQ-788 final compound E08 A549 24 1546 Metaphase 0.4885425609192366 4.307844656139108e-87 BR00116994 AMG900 final compound N09 A549 24 798 Metaphase 0.635269340752763 5.2313547558246185e-87 BR00116993 CYT-997 final compound E06 A549 24 456 Metaphase +0.5842490842490843 1.1727251692118554e-86 BR00116994 briciclib final compound H01 A549 24 546 Metaphase +0.6526806526806527 1.435052457707081e-86 BR00116992 colchicine final compound K17 A549 24 429 Metaphase +0.5574966150142922 7.183128879953795e-83 BR00116994 epothilone-b final compound F07 A549 24 575 Metaphase +0.5499153976311336 1.9090135313011358e-82 BR00116992 BI-2536 final compound I14 A549 24 591 Metaphase +0.5877576177818868 5.816278933381817e-82 BR00116993 CYT-997 final compound C09 A549 24 509 Metaphase +0.5296346927925876 2.7050207836001477e-81 BR00116993 BI-2536 final compound I14 A549 24 630 Metaphase +0.6176993448386066 3.735042264595353e-80 BR00116991 colchicine final compound K17 A549 24 447 Metaphase +0.5761999010390896 4.112568406359477e-80 BR00116992 epothilone-b final compound F07 A549 24 517 Metaphase +0.4824375786039067 5.7816397119733256e-80 BR00116991 AMG900 final compound N09 A549 24 753 Metaphase +0.602859708503143 3.305105375688729e-79 BR00116993 oxibendazole final compound M19 A549 24 465 Metaphase +0.5354503610489422 4.8322878265424e-79 BR00116993 epothilone-b final compound F07 A549 24 597 Metaphase +0.5134038927688579 6.036654808359068e-78 BR00116994 BI-2536 final compound I14 A549 24 645 Metaphase +0.5991379310344828 9.059053197722628e-78 BR00116994 ixabepilone final compound J21 A549 24 464 Metaphase +0.5789514251174414 1.8180323129862366e-77 BR00116991 epothilone-b final compound F07 A549 24 494 Metaphase +0.5735997883750571 1.733354374616243e-76 BR00116991 briciclib final compound H01 A549 24 498 Metaphase +0.599693145261074 4.635921360998409e-76 BR00116992 CYT-997 final compound E06 A549 24 450 Metaphase +0.472630173564753 5.164373369453067e-76 BR00116992 PF-431396 final compound L20 A549 24 749 Metaphase +0.5413550437312186 1.1730659085306723e-75 BR00116991 BI-2536 final compound I14 A549 24 557 Metaphase +0.47796143250688705 1.99309793680443e-75 BR00116991 PF-431396 final compound L20 A549 24 726 Metaphase +0.46219580159762214 6.442927370186006e-75 BR00116993 AMG900 final compound N09 A549 24 770 Metaphase +0.5856075447628594 7.334964000503781e-75 BR00116993 briciclib final compound H01 A549 24 467 Metaphase +0.4663274574134831 8.868615258658088e-73 BR00116991 fludarabine-phosphate final compound N12 A549 24 735 Metaphase +0.6072289156626506 1.2654034906816943e-71 BR00116994 colchicine final compound K17 A549 24 415 Metaphase +0.6237604764156439 2.417493232875483e-70 BR00116993 ixabepilone final compound J21 A549 24 383 Metaphase +0.4454661558109834 2.633306954219108e-70 BR00116994 geldanamycin final compound L01 A549 24 780 Metaphase +0.5390653923161195 6.104990410145651e-69 BR00116993 BI-2536 final compound E21 A549 24 514 Metaphase +0.5669960928522179 1.3835764808800264e-68 BR00116994 oxibendazole final compound M19 A549 24 458 Metaphase +0.4531495198041554 1.277902997871415e-66 BR00116994 ganetespib final compound M10 A549 24 712 Metaphase +0.5036851159682171 4.921154099109641e-66 BR00116992 BI-2536 final compound E21 A549 24 568 Metaphase +0.4185693225945635 1.3433033639484085e-64 BR00116994 fludarabine-phosphate final compound N12 A549 24 816 Metaphase +0.48617936117936117 3.21079191993e-64 BR00116991 BI-2536 final compound E21 A549 24 594 Metaphase +0.5923972402035217 5.460129851403347e-64 BR00116994 CYT-997 final compound C09 A549 24 388 Metaphase +0.5979681299731993 6.038187807475305e-64 BR00116993 colchicine final compound K17 A549 24 381 Metaphase +0.43880485084188786 9.223513875150556e-64 BR00116992 ganetespib final compound I17 A549 24 729 Metaphase +0.44923144057164677 3.4902933337377747e-62 BR00116994 ganetespib final compound I17 A549 24 679 Metaphase +0.428434239818412 1.0118843744087663e-61 BR00116994 PF-431396 final compound L20 A549 24 744 Metaphase +0.54515747932534 1.264710153821701e-61 BR00116994 CYT-997 final compound E06 A549 24 447 Metaphase +0.42511022576361224 2.1126048123564295e-61 BR00116993 fludarabine-phosphate final compound N12 A549 24 753 Metaphase +0.48194624352331605 3.353100719286573e-61 BR00116994 BI-2536 final compound E21 A549 24 576 Metaphase +0.4385256248422116 4.824793714706575e-61 BR00116992 fludarabine-phosphate final compound N12 A549 24 697 Metaphase +0.43060016672395335 1.077274358783559e-59 BR00116994 GSK1070916 final compound C04 A549 24 709 Metaphase +0.5385958003852662 4.6876459455091984e-58 BR00116991 KG-5 final compound C13 A549 24 433 Metaphase +0.41352139654346787 2.1668630675567986e-57 BR00116992 geldanamycin final compound L01 A549 24 741 Metaphase +0.43481442480166344 2.1830239760741034e-57 BR00116991 NVP-HSP990 final compound E23 A549 24 668 Metaphase +0.4140356592820756 4.7743704329400543e-57 BR00116991 geldanamycin final compound L01 A549 24 736 Metaphase +0.40117119441928556 8.466790411359927e-56 BR00116994 aminopurvalanol-a final compound K03 A549 24 769 Metaphase +0.4343833195900577 8.664097913362124e-56 BR00116993 ganetespib final compound I17 A549 24 650 Metaphase +0.33667883211678834 2.014855552771967e-55 BR00116991 quinine final compound A05 A549 24 1096 Metaphase +0.4342214389384201 2.5306740102028196e-54 BR00116994 danusertib final compound N18 A549 24 636 Metaphase +0.4257045143011704 3.449668401671926e-54 BR00116993 PF-431396 final compound L20 A549 24 659 Metaphase +0.4553542164161633 2.202406150793013e-53 BR00116992 NVP-HSP990 final compound E23 A549 24 565 Metaphase +0.41267043107010054 6.237064397817728e-53 BR00116992 GSK1070916 final compound C04 A549 24 685 Metaphase +0.5141187665725772 1.5554628257940617e-52 BR00116992 KG-5 final compound C13 A549 24 432 Metaphase +0.4218009478672986 7.384282331153915e-51 BR00116991 ganetespib final compound M10 A549 24 633 Metaphase +0.41782371294851794 8.272424568908446e-51 BR00116991 danusertib final compound N18 A549 24 641 Metaphase +0.4257934264717758 3.445390636249569e-50 BR00116994 TG-02 final compound L21 A549 24 610 Metaphase +0.4439011102614677 1.5367674933687618e-49 BR00116994 PHA-793887 final compound E13 A549 24 553 Metaphase +0.39912249028940316 1.4878083024581262e-48 BR00116993 aminopurvalanol-a final compound K03 A549 24 675 Metaphase +0.49705071242531024 1.8609295162275386e-48 BR00116994 KG-5 final compound C13 A549 24 427 Metaphase +0.4160730125672854 2.104682370091326e-47 BR00116992 danusertib final compound N18 A549 24 603 Metaphase +0.3046820569057684 5.828073469980639e-47 BR00116991 polydatin final compound K08 A549 24 1132 Metaphase +0.40721617610685135 1.0713023259951736e-46 BR00116992 ganetespib final compound M10 A549 24 622 Metaphase +0.3777147216218403 2.7654183092872305e-46 BR00116992 aminopurvalanol-a final compound K03 A549 24 723 Metaphase +0.4436426130050481 7.803242754494903e-46 BR00116994 NVP-HSP990 final compound E23 A549 24 511 Metaphase +0.41718307961740536 5.809052164714103e-45 BR00116991 ganetespib final compound I17 A549 24 571 Metaphase +0.4066666666666667 9.387227644443509e-45 BR00116992 danusertib final compound E05 A549 24 600 Metaphase +0.3586835879440296 1.1727099248177892e-43 BR00116994 AZ191 final compound I18 A549 24 755 Metaphase +0.3544519830799514 7.870424558054635e-43 BR00116993 danusertib final compound N18 A549 24 758 Metaphase +0.3897893030794165 1.596325804384172e-42 BR00116993 NVP-HSP990 final compound E23 A549 24 618 Metaphase +0.35901757966898523 4.4250977348414124e-40 BR00116993 GSK1070916 final compound C04 A549 24 694 Metaphase +0.372122528571076 7.968835276564708e-40 BR00116993 danusertib final compound E05 A549 24 638 Metaphase +0.36437593273395696 1.1747030426951897e-39 BR00116993 ganetespib final compound M10 A549 24 662 Metaphase +0.42407279605347237 1.4341691079003504e-39 BR00116994 PHA-793887 final compound I06 A549 24 483 Metaphase +0.24360195658380754 1.8420234419338267e-39 BR00116991 PETCM final compound I04 A549 24 1492 Metaphase +0.38153890821380115 2.947809573275624e-39 BR00116992 PHA-793887 final compound I06 A549 24 598 Metaphase +0.43612334801762115 3.586373179288127e-39 BR00116993 KG-5 final compound C13 A549 24 454 Metaphase +0.4080808080808081 2.980187748009628e-37 BR00116992 PHA-793887 final compound E13 A549 24 495 Metaphase +0.3617609831781806 5.727185555221591e-37 BR00116993 PHA-793887 final compound I06 A549 24 628 Metaphase +0.38930150870733615 1.847089153362166e-36 BR00116993 TG-02 final compound L21 A549 24 531 Metaphase +0.3566350710900474 2.1029729374848876e-36 BR00116994 danusertib final compound E05 A549 24 633 Metaphase +0.35299859906405556 1.1907524861912083e-35 BR00116993 AZ191 final compound I18 A549 24 636 Metaphase +0.39215686274509803 2.204404547058311e-35 BR00116991 TG-02 final compound L21 A549 24 510 Metaphase +0.33115429567560073 5.977548728501053e-35 BR00116992 AZ191 final compound I18 A549 24 710 Metaphase +0.3530016583747927 9.919132731599847e-34 BR00116994 UNC2025 final compound N06 A549 24 600 Metaphase +0.4054012645169198 6.126876511997464e-33 BR00116991 PHA-793887 final compound E13 A549 24 442 Metaphase +0.3710471863613872 2.573919980824167e-32 BR00116993 PHA-793887 final compound E13 A549 24 517 Metaphase +0.24422011788175424 2.4135986031837817e-31 BR00116993 polydatin final compound K08 A549 24 1177 Metaphase +0.4566266760762174 4.380934210984206e-31 BR00116992 GK921 final compound H24 A549 24 325 Metaphase +0.2212202199748555 4.821767569409797e-31 BR00116994 polydatin final compound K08 A549 24 1421 Metaphase +0.35091733663162233 6.2574233369653746e-30 BR00116992 PF-03758309 final compound N21 A549 24 539 Metaphase 0.2642099928836098 4.5639923279970066e-48 BR00116991 BQ-788 final compound E08 A549 24 1546 MetaphaseAlignment 0.4503651767455448 4.007658235201702e-45 BR00116992 CYT-997 final compound C09 A549 24 489 MetaphaseAlignment 0.43950012373174957 9.30322447116957e-40 BR00116992 CYT-997 final compound E06 A549 24 450 MetaphaseAlignment @@ -109,6 +1009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.3364634454221341 1.9113824756099314e-35 BR00116992 fludarabine-phosphate final compound N12 A549 24 697 MetaphaseAlignment 0.41442953020134227 7.723164232839659e-35 BR00116991 colchicine final compound K17 A549 24 447 MetaphaseAlignment 0.40861171857325995 5.614536146076023e-34 BR00116994 CYT-997 final compound E06 A549 24 447 MetaphaseAlignment +0.42982631396680787 7.612721037285523e-33 BR00116994 CYT-997 final compound C09 A549 24 388 MetaphaseAlignment +0.3890473017988008 9.742501814124509e-33 BR00116992 oxibendazole final compound M19 A549 24 475 MetaphaseAlignment +0.3111235059760956 1.0229452180312358e-32 BR00116993 fludarabine-phosphate final compound N12 A549 24 753 MetaphaseAlignment +0.4709102378868969 3.532541128636811e-32 BR00116991 romidepsin final compound N19 A549 24 314 MetaphaseAlignment +0.39779395783525323 7.930548745518832e-31 BR00116991 oxibendazole final compound M19 A549 24 428 MetaphaseAlignment +0.3962703962703963 1.8329210156435627e-30 BR00116992 colchicine final compound K17 A549 24 429 MetaphaseAlignment +0.39174899495338295 4.9013439863615185e-30 BR00116992 KG-5 final compound C13 A549 24 432 MetaphaseAlignment +0.4258241758241758 5.543771097206915e-30 BR00116994 romidepsin final compound N19 A549 24 364 MetaphaseAlignment +0.381057268722467 9.301698005214134e-30 BR00116993 KG-5 final compound C13 A549 24 454 MetaphaseAlignment +0.3604477791405142 2.2646807208791562e-29 BR00116991 briciclib final compound H01 A549 24 498 MetaphaseAlignment +0.38138163706218536 1.5353916549230996e-28 BR00116991 KG-5 final compound C13 A549 24 433 MetaphaseAlignment +0.3898305084745763 2.2038020305315168e-28 BR00116992 TG-101348 final compound M20 A549 24 413 MetaphaseAlignment +0.3315018315018315 5.864706006378684e-27 BR00116994 briciclib final compound H01 A549 24 546 MetaphaseAlignment +0.2706894258763433 6.567618769150066e-26 BR00116991 NNC-55-0396 final compound A16 A549 24 791 MetaphaseAlignment +0.27087140190588466 8.50973328196331e-26 BR00116994 geldanamycin final compound L01 A549 24 780 MetaphaseAlignment +0.3469152033054747 3.760343771937806e-25 BR00116991 ixabepilone final compound J21 A549 24 463 MetaphaseAlignment +0.27757202937668696 9.021593583376434e-25 BR00116994 ganetespib final compound M10 A549 24 712 MetaphaseAlignment +0.2672576800963915 3.354630479539588e-24 BR00116994 AZ191 final compound I18 A549 24 755 MetaphaseAlignment +0.2871433619978796 3.556468182484753e-24 BR00116993 ganetespib final compound I17 A549 24 650 MetaphaseAlignment +0.25591171676494556 4.597876279486746e-24 BR00116994 fludarabine-phosphate final compound N12 A549 24 816 MetaphaseAlignment +0.2807031243028102 9.051950713508404e-24 BR00116991 NVP-HSP990 final compound E23 A549 24 668 MetaphaseAlignment +0.26668952157067605 9.75050263054216e-24 BR00116992 geldanamycin final compound L01 A549 24 741 MetaphaseAlignment +0.33336826279101556 1.514130202063631e-23 BR00116993 briciclib final compound H01 A549 24 467 MetaphaseAlignment +0.26717504032318845 1.7830335713571772e-23 BR00116992 ganetespib final compound I17 A549 24 729 MetaphaseAlignment +0.35180722891566263 3.4521342064251165e-23 BR00116994 colchicine final compound K17 A549 24 415 MetaphaseAlignment +0.363651816797215 5.422442192905919e-23 BR00116994 TG-101348 final compound M20 A549 24 384 MetaphaseAlignment +0.258696392607511 3.4025124369552204e-22 BR00116991 geldanamycin final compound L01 A549 24 736 MetaphaseAlignment +0.3235569063572103 4.8541256577414225e-22 BR00116993 oxibendazole final compound M19 A549 24 465 MetaphaseAlignment +0.27492974861395914 1.7896889785773333e-21 BR00116993 BI-2536 final compound I14 A549 24 630 MetaphaseAlignment +0.3879015721120984 4.8746341175764e-21 BR00116993 romidepsin final compound N19 A549 24 304 MetaphaseAlignment +0.19532635254940967 7.456496495910857e-21 BR00116992 ingenol-mebutate final compound M11 A549 24 1217 MetaphaseAlignment +0.23972913295838857 1.1529360312726193e-20 BR00116992 NNC-55-0396 final compound A16 A549 24 802 MetaphaseAlignment +0.20437956204379562 1.9367033469846036e-20 BR00116991 quinine final compound A05 A549 24 1096 MetaphaseAlignment +0.23987270300790473 9.908807426069258e-20 BR00116991 NSC-663284 final compound G06 A549 24 765 MetaphaseAlignment +0.2726415321030373 1.9360723789282189e-19 BR00116992 buparlisib final compound D11 A549 24 578 MetaphaseAlignment +0.28841751350534545 2.7247176400119804e-19 BR00116993 BI-2536 final compound E21 A549 24 514 MetaphaseAlignment +0.2453913353538955 3.235258353634428e-19 BR00116992 AZ191 final compound I18 A549 24 710 MetaphaseAlignment +0.2673434856175973 5.589655158933659e-19 BR00116992 BI-2536 final compound I14 A549 24 591 MetaphaseAlignment +0.26801506544311965 7.402062403497449e-19 BR00116991 buparlisib final compound L12 A549 24 581 MetaphaseAlignment +0.31195145439821403 8.15102642909112e-19 BR00116994 KG-5 final compound C13 A549 24 427 MetaphaseAlignment +0.1571262116841093 1.1168797630785422e-18 BR00116994 LY2109761 final compound M02 A549 24 1690 MetaphaseAlignment +0.2810006958888731 2.6296775662631922e-18 BR00116994 NVP-HSP990 final compound E23 A549 24 511 MetaphaseAlignment +0.2754272687368138 3.541457751011369e-18 BR00116992 ixabepilone final compound J21 A549 24 531 MetaphaseAlignment +0.2527646129541864 3.6265903989751426e-18 BR00116991 ganetespib final compound M10 A549 24 633 MetaphaseAlignment +0.20569620253164558 5.82859028997512e-18 BR00116993 ingenol-mebutate final compound M11 A549 24 948 MetaphaseAlignment +0.24179130529645992 7.492191171388041e-18 BR00116994 ganetespib final compound I17 A549 24 679 MetaphaseAlignment +0.2630797398748362 7.933250849768345e-18 BR00116991 ganetespib final compound I17 A549 24 571 MetaphaseAlignment +0.3071299278309316 8.403214530505672e-18 BR00116991 GK921 final compound H24 A549 24 413 MetaphaseAlignment +0.2648738947186513 9.084311669468292e-18 BR00116991 BI-2536 final compound I14 A549 24 557 MetaphaseAlignment +0.21091514790070068 1.7358983719469855e-17 BR00116993 BAX-channel-blocker final compound I19 A549 24 871 MetaphaseAlignment +0.3700412567438908 3.1808158769772556e-17 BR00116992 romidepsin final compound N19 A549 24 274 MetaphaseAlignment +0.35161457980249927 5.433780260225039e-17 BR00116992 NSC-632839 final compound M16 A549 24 298 MetaphaseAlignment +0.2851068719834521 6.054395259548108e-17 BR00116994 oxibendazole final compound M19 A549 24 458 MetaphaseAlignment +0.22356091030789826 9.121753881454446e-17 BR00116991 SU3327 final compound I20 A549 24 747 MetaphaseAlignment +0.22212483399734395 9.194034441584242e-17 BR00116993 azeliragon final compound C08 A549 24 753 MetaphaseAlignment +0.24397990065721495 1.0152890077172115e-16 BR00116993 NVP-HSP990 final compound E23 A549 24 618 MetaphaseAlignment +0.24359489652898014 1.1041991614038286e-16 BR00116992 ganetespib final compound M10 A549 24 622 MetaphaseAlignment +0.24791837291837293 1.6349583740238103e-16 BR00116991 BI-2536 final compound E21 A549 24 594 MetaphaseAlignment +0.21271498115338247 1.675085286986759e-16 BR00116991 AZ191 final compound I18 A549 24 809 MetaphaseAlignment +0.2540025908757472 1.6837343430671513e-16 BR00116992 NVP-HSP990 final compound E23 A549 24 565 MetaphaseAlignment +0.18768046198267566 2.0892480330361512e-16 BR00116994 ingenol-mebutate final compound M11 A549 24 1039 MetaphaseAlignment +0.2577696526508227 2.247349089238525e-16 BR00116992 buparlisib final compound L12 A549 24 547 MetaphaseAlignment +0.33071747824041403 3.0295505680021806e-16 BR00116992 GK921 final compound H24 A549 24 325 MetaphaseAlignment +0.2692778964449522 4.0801187367986835e-16 BR00116994 buparlisib final compound D11 A549 24 491 MetaphaseAlignment +0.23665384959313243 4.563190412755387e-16 BR00116993 AZ191 final compound I18 A549 24 636 MetaphaseAlignment +0.30334005083137694 5.000532800192334e-16 BR00116993 colchicine final compound K17 A549 24 381 MetaphaseAlignment +0.3020908287247384 6.037467330118765e-16 BR00116993 ixabepilone final compound J21 A549 24 383 MetaphaseAlignment +0.24216813608429438 8.109608431130603e-16 BR00116993 buparlisib final compound L12 A549 24 596 MetaphaseAlignment +0.13858141176456404 1.1067905779657108e-15 BR00116992 LY2109761 final compound M02 A549 24 1822 MetaphaseAlignment +0.3512103838190795 1.59591304152094e-15 BR00116991 AR-12 final compound C10 A549 24 273 MetaphaseAlignment +0.24171524179620035 2.477315042925117e-15 BR00116994 BI-2536 final compound E21 A549 24 576 MetaphaseAlignment +0.2433971137899453 3.2370253883759978e-15 BR00116992 BI-2536 final compound E21 A549 24 568 MetaphaseAlignment +0.4214817440623892 3.346006317113803e-15 BR00116991 ponatinib final compound C20 A549 24 182 MetaphaseAlignment +0.28878469665852935 4.390457032472853e-15 BR00116993 NSC-632839 final compound M16 A549 24 394 MetaphaseAlignment +0.2242610927092054 4.414735919938287e-15 BR00116993 ganetespib final compound M10 A549 24 662 MetaphaseAlignment +0.17784284352444504 4.817340331711396e-15 BR00116991 ingenol-mebutate final compound M11 A549 24 1050 MetaphaseAlignment +0.19515199297074817 5.706407507475086e-15 BR00116994 NNC-55-0396 final compound A16 A549 24 869 MetaphaseAlignment +0.20541946978874062 6.0241189373587296e-15 BR00116993 NNC-55-0396 final compound A16 A549 24 779 MetaphaseAlignment +0.20899470899470898 7.30377860721092e-15 BR00116994 azeliragon final compound C08 A549 24 756 MetaphaseAlignment +0.2586887952750905 9.231549368079633e-15 BR00116994 buparlisib final compound L12 A549 24 485 MetaphaseAlignment +0.2650862068965517 9.676476176843985e-15 BR00116994 ixabepilone final compound J21 A549 24 464 MetaphaseAlignment +0.2616941529235382 2.0969399596403244e-14 BR00116991 delanzomib final compound L11 A549 24 464 MetaphaseAlignment +0.31084443573667714 4.3615256468130846e-14 BR00116991 CYT-997 final compound E06 A549 24 319 MetaphaseAlignment +0.19014128057659116 9.136512760568525e-14 BR00116992 SU3327 final compound I20 A549 24 843 MetaphaseAlignment +0.20890662029222717 1.2908401750179318e-13 BR00116991 7-hydroxystaurosporine final compound L04 A549 24 684 MetaphaseAlignment +0.29878048780487804 1.648776655627775e-13 BR00116991 TG-101348 final compound M20 A549 24 328 MetaphaseAlignment +0.26275577996279564 2.219175237585273e-13 BR00116994 AZD7762 final compound K11 A549 24 424 MetaphaseAlignment +0.13876221498371336 2.6765580142540006e-13 BR00116994 PP-2 final compound J10 A549 24 1535 MetaphaseAlignment +0.14693469855825192 2.846549520299965e-13 BR00116993 PP-2 final compound J10 A549 24 1364 MetaphaseAlignment +0.3413654618473896 2.94753996089393e-13 BR00116993 ponatinib final compound C20 A549 24 249 MetaphaseAlignment 0.5152662699957368 2.7061975017688443e-89 BR00116991 fludarabine-phosphate final compound N12 A549 24 735 OutOfFocus 0.3818711067511399 5.685788705730748e-88 BR00116992 polydatin final compound K08 A549 24 1346 OutOfFocus 0.35247867066237576 7.05208882190682e-79 BR00116994 polydatin final compound K08 A549 24 1421 OutOfFocus @@ -119,6 +1109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.35187912264205917 3.04425422964582e-65 BR00116993 polydatin final compound K08 A549 24 1177 OutOfFocus 0.26770763823209043 5.230215201607714e-58 BR00116992 LY2109761 final compound M02 A549 24 1822 OutOfFocus 0.40155935315720886 1.1869391339199239e-53 BR00116991 geldanamycin final compound L01 A549 24 736 OutOfFocus +0.3177790691498502 3.7063508636142005e-51 BR00116991 polydatin final compound K08 A549 24 1132 OutOfFocus +0.24848613679952095 1.2335973825274378e-48 BR00116993 LY2109761 final compound M02 A549 24 1777 OutOfFocus +0.39335338265347103 1.1028981927638202e-46 BR00116991 NVP-HSP990 final compound E23 A549 24 668 OutOfFocus +0.3633270022158911 2.1179119243357953e-43 BR00116992 ganetespib final compound I17 A549 24 729 OutOfFocus +0.348354455251007 1.5273213503965394e-42 BR00116994 geldanamycin final compound L01 A549 24 780 OutOfFocus +0.3590797815579687 1.7536090754331437e-41 BR00116994 ganetespib final compound M10 A549 24 712 OutOfFocus +0.35943708067419405 1.8682644699252682e-39 BR00116994 ganetespib final compound I17 A549 24 679 OutOfFocus +0.364193662386618 7.053461446827805e-39 BR00116993 ganetespib final compound I17 A549 24 650 OutOfFocus +0.41742414757313967 1.192621827594774e-38 BR00116992 CYT-997 final compound C09 A549 24 489 OutOfFocus +0.39335875804152703 1.332851623080277e-35 BR00116993 CYT-997 final compound C09 A549 24 509 OutOfFocus +0.37167648463620445 1.5084251319500053e-35 BR00116991 ganetespib final compound I17 A549 24 571 OutOfFocus +0.26824817518248173 4.4010856546198403e-35 BR00116991 quinine final compound A05 A549 24 1096 OutOfFocus +0.3148122333155477 4.4855579371508125e-35 BR00116991 NNC-55-0396 final compound A16 A549 24 791 OutOfFocus +0.21580716937957561 5.898750493820094e-35 BR00116994 LY2109761 final compound M02 A549 24 1690 OutOfFocus +0.35098496527915035 2.568246216033168e-34 BR00116992 PP-121 final compound B16 A549 24 615 OutOfFocus +0.31778111531931563 1.0799254698832226e-33 BR00116992 geldanamycin final compound L01 A549 24 741 OutOfFocus +0.34281200631911535 2.271678322737873e-33 BR00116991 ganetespib final compound M10 A549 24 633 OutOfFocus +0.3310925105312107 2.965777986488333e-33 BR00116993 aminopurvalanol-a final compound K03 A549 24 675 OutOfFocus +0.21954397394136807 8.254141968156832e-33 BR00116994 PP-2 final compound J10 A549 24 1535 OutOfFocus +0.33801735509934866 4.678803409223605e-32 BR00116992 ganetespib final compound M10 A549 24 622 OutOfFocus +0.2188389427695645 7.028646371946454e-32 BR00116991 PETCM final compound I04 A549 24 1492 OutOfFocus +0.39410055129434324 1.8528961538503873e-31 BR00116991 colchicine final compound K17 A549 24 447 OutOfFocus +0.30164903300704465 8.061684730297983e-31 BR00116994 AZ191 final compound I18 A549 24 755 OutOfFocus +0.34067796610169493 9.66458549031603e-31 BR00116993 PP-121 final compound B16 A549 24 590 OutOfFocus +0.22922308992347903 4.570838868209708e-30 BR00116992 PP-2 final compound J10 A549 24 1287 OutOfFocus +0.3809026972718139 4.885824135813632e-30 BR00116993 CYT-997 final compound E06 A549 24 456 OutOfFocus +0.29340410424035124 1.119601937000502e-29 BR00116994 aminopurvalanol-a final compound K03 A549 24 769 OutOfFocus +0.3397548161120841 1.3316707650665905e-29 BR00116994 PP-121 final compound B16 A549 24 571 OutOfFocus +0.34042858703625667 1.4652603909071764e-29 BR00116992 NVP-HSP990 final compound E23 A549 24 565 OutOfFocus +0.3797525365008661 1.5313171199023422e-29 BR00116992 CYT-997 final compound E06 A549 24 450 OutOfFocus +0.2979422631637752 9.197082123749507e-29 BR00116992 aminopurvalanol-a final compound K03 A549 24 723 OutOfFocus +0.3776223776223776 1.2475517359146339e-27 BR00116992 colchicine final compound K17 A549 24 429 OutOfFocus +0.3493121077351511 5.360361513564442e-27 BR00116992 briciclib final compound H01 A549 24 490 OutOfFocus +0.27089380274382335 1.38904957760136e-26 BR00116991 AZ191 final compound I18 A549 24 809 OutOfFocus +0.3420388139383883 1.701616811783059e-26 BR00116991 briciclib final compound H01 A549 24 498 OutOfFocus +0.38350781853538984 4.245884670754031e-26 BR00116994 CYT-997 final compound C09 A549 24 388 OutOfFocus +0.35866073448457886 5.6711877272071e-26 BR00116994 CYT-997 final compound E06 A549 24 447 OutOfFocus +0.22132409876968082 7.216743355204148e-26 BR00116991 A-987306 final compound P20 A549 24 1180 OutOfFocus +0.30383996055661333 8.507944802648953e-26 BR00116993 NVP-HSP990 final compound E23 A549 24 618 OutOfFocus +0.33339228524523357 1.1823700846585941e-25 BR00116994 NVP-HSP990 final compound E23 A549 24 511 OutOfFocus +0.22665457842248413 3.080467285958872e-25 BR00116991 JTE-607 final compound C14 A549 24 1103 OutOfFocus +0.23253588516746412 3.521026606457559e-25 BR00116991 dexamethasone final compound A21 A549 24 1045 OutOfFocus +0.27309236947791166 6.499091527825392e-25 BR00116991 SU3327 final compound I20 A549 24 747 OutOfFocus +0.27483607693983875 4.487056817890646e-24 BR00116992 AZ191 final compound I18 A549 24 710 OutOfFocus +0.1990245985761097 4.715373196396765e-24 BR00116993 PP-2 final compound J10 A549 24 1364 OutOfFocus +0.35097804825038037 5.577060462894744e-24 BR00116991 oxibendazole final compound M19 A549 24 428 OutOfFocus +0.3466704270920914 1.4389113627696384e-23 BR00116991 KG-5 final compound C13 A549 24 433 OutOfFocus +0.2791513485968041 2.5908591084129678e-23 BR00116993 ganetespib final compound M10 A549 24 662 OutOfFocus +0.2734813223535028 4.1706960967149486e-23 BR00116991 7-hydroxystaurosporine final compound L04 A549 24 684 OutOfFocus +0.22774839994742324 4.261185422434826e-23 BR00116991 fludarabine final compound B06 A549 24 994 OutOfFocus +0.2807684282690989 1.634570783638329e-22 BR00116993 AZ191 final compound I18 A549 24 636 OutOfFocus +0.33821957060987085 2.2086947132702673e-22 BR00116992 KG-5 final compound C13 A549 24 432 OutOfFocus +0.2929373251813164 4.415739678718461e-22 BR00116994 PF-03758309 final compound N21 A549 24 569 OutOfFocus +0.22934763938668712 5.476419899108862e-22 BR00116991 DDR1-IN-1 final compound A23 A549 24 935 OutOfFocus +0.3134399289362647 3.2721820093343786e-21 BR00116992 oxibendazole final compound M19 A549 24 475 OutOfFocus +0.19870553438898944 4.268469436377636e-21 BR00116991 desonide final compound E16 A549 24 1194 OutOfFocus +0.18392630042412966 6.1183144236742515e-21 BR00116991 RGFP966 final compound H03 A549 24 1386 OutOfFocus +0.19737905617434448 2.4869250705158134e-20 BR00116993 desonide final compound E16 A549 24 1167 OutOfFocus +0.242788147312368 3.292203070560003e-20 BR00116993 7-hydroxystaurosporine final compound L04 A549 24 764 OutOfFocus +0.2987323943661972 3.5444396435388807e-20 BR00116991 PF-03758309 final compound N21 A549 24 497 OutOfFocus +0.1648869046254897 3.56031980066327e-20 BR00116991 salicylic-acid final compound O03 A549 24 1657 OutOfFocus +0.2330059454774084 8.338990241300432e-20 BR00116993 JTE-607 final compound C14 A549 24 808 OutOfFocus +0.22330260333607443 1.3481303504827606e-19 BR00116993 BAX-channel-blocker final compound I19 A549 24 871 OutOfFocus +0.20393336333330273 1.6241055622588646e-19 BR00116993 fludarabine final compound B06 A549 24 1042 OutOfFocus +0.18502409780181028 1.924877625241572e-19 BR00116991 loperamide final compound P23 A549 24 1269 OutOfFocus +0.2783882783882784 4.969413349188478e-19 BR00116994 briciclib final compound H01 A549 24 546 OutOfFocus +0.18881372649365877 5.892800632557914e-19 BR00116994 SKLB1002 final compound P17 A549 24 1181 OutOfFocus +0.20307209061139045 6.047929041805441e-19 BR00116994 fludarabine final compound B06 A549 24 1019 OutOfFocus +0.2998313343328336 7.546819994589007e-19 BR00116991 delanzomib final compound L11 A549 24 464 OutOfFocus +0.22287780516657635 1.3218606574712515e-18 BR00116991 BAX-channel-blocker final compound I19 A549 24 828 OutOfFocus +0.30946179605594343 1.5516279894627022e-18 BR00116994 KG-5 final compound C13 A549 24 427 OutOfFocus +0.1820188283687116 2.479519587835568e-18 BR00116991 SKLB1002 final compound P17 A549 24 1228 OutOfFocus +0.18325499551066685 4.186309206019244e-18 BR00116993 SKLB1002 final compound P17 A549 24 1198 OutOfFocus +0.29129345300469267 5.001059474629118e-18 BR00116993 briciclib final compound H01 A549 24 467 OutOfFocus +0.29275049300403794 6.11454639339983e-18 BR00116991 ixabepilone final compound J21 A549 24 463 OutOfFocus +0.30843373493975906 7.838398411366217e-18 BR00116994 colchicine final compound K17 A549 24 415 OutOfFocus +0.3069830038317779 8.44858969840818e-18 BR00116991 GK921 final compound H24 A549 24 413 OutOfFocus +0.2907488986784141 2.5663453834111395e-17 BR00116993 KG-5 final compound C13 A549 24 454 OutOfFocus +0.27058823529411763 7.880107933862791e-17 BR00116991 TG-02 final compound L21 A549 24 510 OutOfFocus +0.19426235590956314 8.949958910613673e-17 BR00116991 flupirtine final compound A19 A549 24 984 OutOfFocus +0.1702700145330852 1.0011034146373575e-16 BR00116991 deferasirox final compound L14 A549 24 1282 OutOfFocus +0.21401819237708966 1.2069180923710412e-16 BR00116992 NNC-55-0396 final compound A16 A549 24 802 OutOfFocus +0.2573304735192212 1.297229494480802e-16 BR00116991 PP-121 final compound B16 A549 24 550 OutOfFocus +0.28782570503457505 1.3673939526047072e-16 BR00116991 PHA-793887 final compound E13 A549 24 442 OutOfFocus +0.19319381520428947 1.685162183125709e-16 BR00116992 dexamethasone final compound A21 A549 24 982 OutOfFocus +0.34777303233679074 2.003873366596475e-16 BR00116992 NSC-632839 final compound M16 A549 24 298 OutOfFocus +0.22514909365202837 2.323766072047231e-16 BR00116994 7-hydroxystaurosporine final compound L04 A549 24 711 OutOfFocus +0.18608561441735894 2.5123301156577036e-16 BR00116991 ingenol-mebutate final compound M11 A549 24 1050 OutOfFocus +0.16420468447627734 2.654301265587649e-16 BR00116991 regorafenib final compound P13 A549 24 1340 OutOfFocus +0.16888233073676265 3.2833089279580607e-16 BR00116991 AZD1283 final compound P19 A549 24 1267 OutOfFocus 0.32243310300535777 9.71048806942421e-72 BR00116991 BQ-788 final compound E08 A549 24 1546 Polylobed 0.28722516126603526 2.2464718167816112e-49 BR00116992 polydatin final compound K08 A549 24 1346 Polylobed 0.30891077972837444 2.7764766116701814e-48 BR00116991 polydatin final compound K08 A549 24 1132 Polylobed @@ -129,6 +1209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.34930146082337316 3.3317910261755835e-41 BR00116993 fludarabine-phosphate final compound N12 A549 24 753 Polylobed 0.22723400593999335 9.568439147079417e-41 BR00116993 LY2109761 final compound M02 A549 24 1777 Polylobed 0.3193405567355147 2.689523556195273e-40 BR00116992 AMG900 final compound N09 A549 24 882 Polylobed +0.3537703996075558 3.132492355219922e-39 BR00116992 fludarabine-phosphate final compound N12 A549 24 697 Polylobed +0.2477489542891934 8.627374586609273e-39 BR00116994 polydatin final compound K08 A549 24 1421 Polylobed +0.3353591349279677 1.6487575450095525e-38 BR00116991 NSC-663284 final compound G06 A549 24 765 Polylobed +0.3255079354597284 4.854053373896211e-38 BR00116994 AMG900 final compound N09 A549 24 798 Polylobed +0.28200192492781523 8.776736263281775e-37 BR00116994 ingenol-mebutate final compound M11 A549 24 1039 Polylobed +0.33287363991918295 1.534488170977263e-36 BR00116991 fludarabine-phosphate final compound N12 A549 24 735 Polylobed +0.2612687813021703 2.4294859485927387e-36 BR00116991 PP-2 final compound J10 A549 24 1198 Polylobed +0.2567276986152167 1.2956282958798533e-34 BR00116993 polydatin final compound K08 A549 24 1177 Polylobed +0.347068145800317 4.189836514791649e-34 BR00116991 danusertib final compound E05 A549 24 631 Polylobed +0.2462381881676253 5.909553442673191e-33 BR00116992 ingenol-mebutate final compound M11 A549 24 1217 Polylobed +0.2998007194366102 3.994466954553958e-31 BR00116993 AMG900 final compound N09 A549 24 770 Polylobed +0.27109704641350213 4.758664196058264e-31 BR00116993 ingenol-mebutate final compound M11 A549 24 948 Polylobed +0.3265692803007579 1.7513435815192432e-30 BR00116994 danusertib final compound E05 A549 24 633 Polylobed +0.32484140893046676 2.5743236323011222e-30 BR00116993 danusertib final compound E05 A549 24 638 Polylobed +0.3066397221794218 4.955847055568786e-30 BR00116994 GSK1070916 final compound C04 A549 24 709 Polylobed +0.316812528366242 9.060222137549985e-30 BR00116993 PF-431396 final compound L20 A549 24 659 Polylobed +0.36642460665247695 1.1701158988143175e-29 BR00116992 CYT-997 final compound C09 A549 24 489 Polylobed +0.2935891279991852 9.877302580126644e-29 BR00116994 PF-431396 final compound L20 A549 24 744 Polylobed +0.2772733172140958 2.7864241201373627e-27 BR00116991 NNC-55-0396 final compound A16 A549 24 791 Polylobed +0.24050569703572564 4.647403686590421e-27 BR00116991 ingenol-mebutate final compound M11 A549 24 1050 Polylobed +0.21546322246711352 1.1030007322552114e-26 BR00116992 PP-2 final compound J10 A549 24 1287 Polylobed +0.20799598952629506 2.1978988529795008e-26 BR00116993 PP-2 final compound J10 A549 24 1364 Polylobed +0.2877536253100388 9.334237418808108e-26 BR00116993 GSK1070916 final compound C04 A549 24 694 Polylobed +0.2799951093892086 1.3692590674397545e-25 BR00116991 GSK1070916 final compound C04 A549 24 724 Polylobed +0.2796143250688705 2.166163021210433e-25 BR00116991 PF-431396 final compound L20 A549 24 726 Polylobed +0.2838569154728994 4.0199158559995318e-25 BR00116994 BMS-536924 final compound B15 A549 24 692 Polylobed +0.27105931789309096 4.6528971204421e-25 BR00116993 danusertib final compound N18 A549 24 758 Polylobed +0.2184014246758634 7.531660481978513e-25 BR00116993 desonide final compound E16 A549 24 1167 Polylobed +0.2944669885370694 9.181260187347226e-25 BR00116994 danusertib final compound N18 A549 24 636 Polylobed +0.24992334983136963 2.8785632236376937e-24 BR00116994 NNC-55-0396 final compound A16 A549 24 869 Polylobed +0.2568495613404286 3.982956915583982e-24 BR00116994 fludarabine-phosphate final compound N12 A549 24 816 Polylobed +0.26702269692923897 6.918235358890307e-24 BR00116992 PF-431396 final compound L20 A549 24 749 Polylobed +0.3791208791208791 1.0832431821414984e-23 BR00116994 romidepsin final compound N19 A549 24 364 Polylobed +0.32084440849031165 1.1826271009215208e-23 BR00116993 CYT-997 final compound C09 A549 24 509 Polylobed +0.2946480223467381 1.2652671831210711e-23 BR00116992 danusertib final compound N18 A549 24 603 Polylobed +0.19709996603006502 1.2947159297259537e-23 BR00116991 LY2109761 final compound M02 A549 24 1357 Polylobed +0.2649999100347266 1.3107933466730562e-23 BR00116991 BMS-536924 final compound B15 A549 24 746 Polylobed +0.2632665804772082 1.7184086416883544e-23 BR00116994 AZ191 final compound I18 A549 24 755 Polylobed +0.18501628664495115 2.2737551897369662e-23 BR00116994 PP-2 final compound J10 A549 24 1535 Polylobed +0.25961744887429966 4.6599442078887736e-23 BR00116993 BMS-536924 final compound B15 A549 24 762 Polylobed +0.25626767959842145 5.911108701767257e-23 BR00116993 NNC-55-0396 final compound A16 A549 24 779 Polylobed +0.26504031219666807 2.1657974231292033e-22 BR00116992 AZ191 final compound I18 A549 24 710 Polylobed +0.277245027301092 2.7841681637840987e-22 BR00116991 danusertib final compound N18 A549 24 641 Polylobed +0.2590105367883146 4.574322811442471e-22 BR00116992 ganetespib final compound I17 A549 24 729 Polylobed +0.39068191530493884 7.931597368559127e-22 BR00116991 romidepsin final compound N19 A549 24 314 Polylobed +0.24604429151281199 9.115531092660906e-22 BR00116992 NNC-55-0396 final compound A16 A549 24 802 Polylobed +0.3501824768907003 9.838490678816216e-22 BR00116994 CYT-997 final compound C09 A549 24 388 Polylobed +0.2497104913678619 3.9717648397974215e-21 BR00116993 azeliragon final compound C08 A549 24 753 Polylobed +0.2440907751252579 5.4673314343622516e-21 BR00116994 geldanamycin final compound L01 A549 24 780 Polylobed +0.25327976900382904 1.3427680715579908e-20 BR00116994 ganetespib final compound M10 A549 24 712 Polylobed +0.31800295621604346 1.862525406502953e-20 BR00116991 colchicine final compound K17 A549 24 447 Polylobed +0.3152289037366988 2.3031475588655703e-20 BR00116992 CYT-997 final compound E06 A549 24 450 Polylobed +0.16529839432486992 4.548215573251564e-20 BR00116991 CC-401 final compound M09 A549 24 1643 Polylobed +0.31277533039647576 5.0942281180895787e-20 BR00116993 KG-5 final compound C13 A549 24 454 Polylobed +0.30856325836617976 1.075434286724181e-19 BR00116993 CYT-997 final compound E06 A549 24 456 Polylobed +0.2584124459466176 1.472825436446479e-19 BR00116992 BMS-536924 final compound B15 A549 24 651 Polylobed +0.2683333333333333 2.1042608203144176e-19 BR00116992 danusertib final compound E05 A549 24 600 Polylobed +0.1903908655490934 2.8352141936216904e-19 BR00116994 desonide final compound E16 A549 24 1184 Polylobed +0.20232253585572507 4.393388829694903e-19 BR00116991 PP-1 final compound A22 A549 24 1039 Polylobed +0.3052509866023176 6.004170020604914e-19 BR00116994 CYT-997 final compound E06 A549 24 447 Polylobed +0.25421771140719546 1.7632440568790265e-18 BR00116993 AZ191 final compound I18 A549 24 636 Polylobed +0.25005772175756863 2.0216881896565027e-18 BR00116993 ganetespib final compound I17 A549 24 650 Polylobed +0.18550887431416682 2.4642517337504072e-18 BR00116993 amlodipine final compound A03 A549 24 1183 Polylobed +0.24078056635555603 5.348066970992119e-18 BR00116992 GSK1070916 final compound C04 A549 24 685 Polylobed +0.35812542720437457 5.856624861868486e-18 BR00116993 romidepsin final compound N19 A549 24 304 Polylobed +0.21261497476532143 9.180643307215499e-18 BR00116993 BAX-channel-blocker final compound I19 A549 24 871 Polylobed +0.22883597883597884 9.253231747910536e-18 BR00116994 azeliragon final compound C08 A549 24 756 Polylobed +0.15282321089650552 1.01585636256836e-17 BR00116994 CC-401 final compound M09 A549 24 1696 Polylobed +0.23460151333003323 1.0281445465500583e-17 BR00116994 7-hydroxystaurosporine final compound L04 A549 24 711 Polylobed +0.26556776556776557 2.460611484684428e-17 BR00116994 briciclib final compound H01 A549 24 546 Polylobed +0.2796402398401066 6.091714716556068e-17 BR00116992 oxibendazole final compound M19 A549 24 475 Polylobed +0.29206761611496024 1.0343716154199922e-16 BR00116992 KG-5 final compound C13 A549 24 432 Polylobed +0.23434948285247686 1.1839008826913363e-16 BR00116991 NVP-HSP990 final compound E23 A549 24 668 Polylobed +0.15843621399176955 2.2117318657905905e-16 BR00116993 dexamethasone final compound O02 A549 24 1458 Polylobed +0.21942884506551738 3.543148640045707e-16 BR00116992 geldanamycin final compound L01 A549 24 741 Polylobed +0.14898520811833504 3.899109966532533e-16 BR00116992 CC-401 final compound M09 A549 24 1620 Polylobed +0.22850160912016582 5.599804352461856e-16 BR00116994 ganetespib final compound I17 A549 24 679 Polylobed +0.21807250325790783 7.456819844876885e-16 BR00116991 geldanamycin final compound L01 A549 24 736 Polylobed +0.29877203002610964 1.0182983128776387e-15 BR00116994 TG-101348 final compound M20 A549 24 384 Polylobed +0.288135593220339 1.6423807427078786e-15 BR00116992 TG-101348 final compound M20 A549 24 413 Polylobed +0.1715723073791829 1.7717337715728506e-15 BR00116992 desonide final compound E16 A549 24 1163 Polylobed +0.28205128205128205 1.9691227639730374e-15 BR00116992 colchicine final compound K17 A549 24 429 Polylobed +0.21073642424200728 2.3658276591472706e-15 BR00116993 7-hydroxystaurosporine final compound L04 A549 24 764 Polylobed +0.18804263119189524 3.167661195706848e-15 BR00116994 PP-1 final compound A22 A549 24 955 Polylobed +0.23206261851760243 3.3263095968931777e-15 BR00116992 ganetespib final compound M10 A549 24 622 Polylobed +0.26155700569433477 3.3460157187319032e-15 BR00116992 briciclib final compound H01 A549 24 490 Polylobed +0.2560601924651767 3.4514568296810695e-15 BR00116994 NVP-HSP990 final compound E23 A549 24 511 Polylobed +0.18510744419967579 3.627203073964026e-15 BR00116992 dexamethasone final compound A21 A549 24 982 Polylobed +0.22063236322097762 3.731288198568331e-15 BR00116991 7-hydroxystaurosporine final compound L04 A549 24 684 Polylobed +0.24187721210488286 3.901437034798645e-15 BR00116991 ganetespib final compound I17 A549 24 571 Polylobed 0.20696844956355007 1.451333388995938e-26 BR00116991 RKI-1447 final compound J04 A549 24 1394 Prometaphase 0.28129344380804094 3.258041049886431e-26 BR00116991 fludarabine-phosphate final compound N12 A549 24 735 Prometaphase 0.26109832686130685 4.862275424421352e-25 BR00116994 fludarabine-phosphate final compound N12 A549 24 816 Prometaphase @@ -139,6 +1309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.24257104913678618 7.206029826445003e-20 BR00116993 azeliragon final compound C08 A549 24 753 Prometaphase 0.1728307254623044 9.468167272090057e-19 BR00116994 RKI-1447 final compound J04 A549 24 1406 Prometaphase 0.22753217408389823 2.8539710070175644e-18 BR00116994 geldanamycin final compound L01 A549 24 780 Prometaphase +0.22886785762322243 1.494484076949915e-16 BR00116993 KU-60019 final compound I07 A549 24 702 Prometaphase +0.303898770670148 3.2257409065207384e-16 BR00116994 TG-101348 final compound M20 A549 24 384 Prometaphase +0.33002547021943573 7.509661796397402e-16 BR00116993 TG-101348 final compound M20 A549 24 319 Prometaphase +0.2048123712571275 1.5196669655843501e-15 BR00116994 KU-60019 final compound I07 A549 24 817 Prometaphase +0.22196619071065157 4.128192723810102e-15 BR00116993 aminopurvalanol-a final compound K03 A549 24 675 Prometaphase +0.15530541688880273 2.652131366926521e-14 BR00116993 RKI-1447 final compound J04 A549 24 1317 Prometaphase +0.20721954824634253 3.183068734640083e-14 BR00116994 BAX-channel-blocker final compound I19 A549 24 733 Prometaphase +0.21596654494051126 7.740210757791408e-14 BR00116993 ganetespib final compound I17 A549 24 650 Prometaphase +0.20213489603794724 9.352095482870162e-14 BR00116994 NVP-ADW742 final compound D16 A549 24 744 Prometaphase +0.3453815261044177 1.4429747868256851e-13 BR00116993 ponatinib final compound C20 A549 24 249 Prometaphase +0.272078628405677 2.808801501480511e-13 BR00116991 puromycin final compound C22 A549 24 392 Prometaphase +0.19444444444444445 6.552100628838545e-13 BR00116994 azeliragon final compound C08 A549 24 756 Prometaphase +0.14782061863773927 9.399313518587546e-13 BR00116992 PP-2 final compound J10 A549 24 1287 Prometaphase +0.19559664139319985 9.407764190374547e-13 BR00116991 geldanamycin final compound L01 A549 24 736 Prometaphase +0.21528428093645485 1.229847888212701e-12 BR00116991 KU-60019 final compound I07 A549 24 598 Prometaphase +0.2876506024096386 1.5366076951940252e-12 BR00116991 TG-101348 final compound M20 A549 24 328 Prometaphase +0.2566585956416465 2.3292574587082136e-12 BR00116992 TG-101348 final compound M20 A549 24 413 Prometaphase +0.2276325851288741 2.7156039476275266e-12 BR00116992 epothilone-b final compound F07 A549 24 517 Prometaphase +0.22120658135283364 3.898399479549429e-12 BR00116992 buparlisib final compound L12 A549 24 547 Prometaphase +0.3392070484581498 5.701811590958742e-12 BR00116994 ponatinib final compound C20 A549 24 227 Prometaphase +0.2807626483087514 9.261932810647196e-12 BR00116994 puromycin final compound C22 A549 24 323 Prometaphase +0.20747365800106388 1.12683691503521e-11 BR00116993 buparlisib final compound L12 A549 24 596 Prometaphase +0.21312928631547282 1.2554171958201293e-11 BR00116991 BI-2536 final compound I14 A549 24 557 Prometaphase +0.21029914106784822 1.5166317341841553e-11 BR00116994 PF-03758309 final compound N21 A549 24 569 Prometaphase +0.20507439257439258 2.1487849160769034e-11 BR00116991 BI-2536 final compound E21 A549 24 594 Prometaphase +0.25257731958762886 2.8061099549503835e-11 BR00116992 AZD7762 final compound I05 A549 24 388 Prometaphase +0.19494949494949496 6.105474987409824e-11 BR00116993 BI-2536 final compound I14 A549 24 630 Prometaphase +0.12966865185199686 6.591657710533391e-11 BR00116994 AC-710 final compound I03 A549 24 1430 Prometaphase +0.18181818181818182 6.71518999656462e-11 BR00116991 PF-431396 final compound L20 A549 24 726 Prometaphase +0.3482255449468564 2.056531072625225e-10 BR00116992 ponatinib final compound C20 A549 24 183 Prometaphase +0.16187299234000493 3.137627637388652e-10 BR00116992 azeliragon final compound C08 A549 24 855 Prometaphase +0.19458544839255498 3.3789424423585567e-10 BR00116992 BI-2536 final compound I14 A549 24 591 Prometaphase +0.17222963951935916 4.07658231185208e-10 BR00116992 PF-431396 final compound L20 A549 24 749 Prometaphase +0.17407099366015943 6.063218560389484e-10 BR00116994 ganetespib final compound M10 A549 24 712 Prometaphase +0.14624290800253928 7.193456991645972e-10 BR00116992 cyclosporine final compound M15 A549 24 1002 Prometaphase +0.19010866436384571 1.228866455011386e-09 BR00116994 BI-2536 final compound E21 A549 24 576 Prometaphase +0.16493144420112046 1.8498644009677664e-09 BR00116991 AMG900 final compound N09 A549 24 753 Prometaphase +0.1993065988674448 2.233340506132815e-09 BR00116993 CYT-997 final compound C09 A549 24 509 Prometaphase +0.2615666513971599 2.427872941029193e-09 BR00116993 puromycin final compound C22 A549 24 295 Prometaphase +0.16467691009355856 2.9231337943311253e-09 BR00116994 PF-431396 final compound L20 A549 24 744 Prometaphase +0.16606637557858442 3.0863128807485135e-09 BR00116992 NVP-ADW742 final compound D16 A549 24 731 Prometaphase +0.18550557477893118 3.555496090680506e-09 BR00116992 buparlisib final compound D11 A549 24 578 Prometaphase +0.21446628291273612 3.561143464544288e-09 BR00116994 KG-5 final compound C13 A549 24 427 Prometaphase +0.15777524111407754 3.5928412281184723e-09 BR00116994 AMG900 final compound N09 A549 24 798 Prometaphase +0.18274566107850176 3.6305673411139666e-09 BR00116993 epothilone-b final compound F07 A549 24 597 Prometaphase +0.23480662983425415 3.6642023412806124e-09 BR00116992 AZD7762 final compound K11 A549 24 362 Prometaphase +0.2173905666779776 3.765038747555616e-09 BR00116991 AZD7762 final compound K11 A549 24 421 Prometaphase +0.17152877553388007 4.197251646298843e-09 BR00116991 NVP-HSP990 final compound E23 A549 24 668 Prometaphase +0.1669266455450666 5.241916711993852e-09 BR00116991 NVP-ADW742 final compound D16 A549 24 704 Prometaphase +0.1402805611222445 5.596513018022683e-09 BR00116992 PP-1 final compound A22 A549 24 998 Prometaphase +0.18702146024161231 5.7624858451126744e-09 BR00116994 PHA-793887 final compound E13 A549 24 553 Prometaphase +0.15834022934152972 6.328423125854234e-09 BR00116993 AMG900 final compound N09 A549 24 770 Prometaphase +0.280298353909465 6.704001530918554e-09 BR00116993 AR-12 final compound C10 A549 24 240 Prometaphase +0.19070628548773064 6.83747297062451e-09 BR00116992 ixabepilone final compound J21 A549 24 531 Prometaphase +0.10431112937373845 6.883397376727419e-09 BR00116993 LY2109761 final compound M02 A549 24 1777 Prometaphase +0.1930187752634959 7.928174506225435e-09 BR00116993 BI-2536 final compound E21 A549 24 514 Prometaphase +0.15732865125426085 8.028825135483523e-09 BR00116994 aminopurvalanol-a final compound K03 A549 24 769 Prometaphase +0.19280735412285321 8.19374130136032e-09 BR00116994 NVP-HSP990 final compound E23 A549 24 511 Prometaphase +0.2791294316166469 8.494020012122224e-09 BR00116992 UNC1999 final compound H19 A549 24 243 Prometaphase +0.17377567140600317 9.198348802307615e-09 BR00116991 ganetespib final compound M10 A549 24 633 Prometaphase +0.14646884394783555 9.2445423589227e-09 BR00116992 AMG900 final compound N09 A549 24 882 Prometaphase +0.20314295564238105 1.0255344162885088e-08 BR00116994 oxibendazole final compound M19 A549 24 458 Prometaphase +0.17063383492932058 1.1270851360803204e-08 BR00116994 BI-2536 final compound I14 A549 24 645 Prometaphase +0.18151748805663506 1.2003404909117368e-08 BR00116992 BI-2536 final compound E21 A549 24 568 Prometaphase +0.1699544839706565 1.7212320301728086e-08 BR00116994 danusertib final compound N18 A549 24 636 Prometaphase +0.2840945006321112 1.7317598881343725e-08 BR00116992 AR-12 final compound C10 A549 24 224 Prometaphase +0.1207258785942492 2.0516723243079585e-08 BR00116993 cediranib final compound L16 A549 24 1250 Prometaphase +0.18836864011423657 3.4199598511224346e-08 BR00116991 epothilone-b final compound F07 A549 24 494 Prometaphase +0.30404690404690404 3.80581890183738e-08 BR00116991 CYT-997 final compound C09 A549 24 185 Prometaphase +0.1738411826432302 4.0839718858101103e-08 BR00116991 buparlisib final compound L12 A549 24 581 Prometaphase +0.2632520325203252 4.443645190083267e-08 BR00116992 LDN-212854 final compound K01 A549 24 250 Prometaphase +0.1939655172413793 4.7824260875005875e-08 BR00116994 ixabepilone final compound J21 A549 24 464 Prometaphase +0.1532258064516129 4.89864125650667e-08 BR00116993 NVP-ADW742 final compound D16 A549 24 744 Prometaphase +0.16587677725118483 5.103593632277951e-08 BR00116992 BAX-channel-blocker final compound I19 A549 24 633 Prometaphase +0.1878024513643388 5.1180516345859e-08 BR00116994 buparlisib final compound L12 A549 24 485 Prometaphase +0.14046954104674655 5.5109063838964486e-08 BR00116993 BAX-channel-blocker final compound I19 A549 24 871 Prometaphase +0.18108594030924127 7.20621448200764e-08 BR00116993 buparlisib final compound D11 A549 24 513 Prometaphase +0.18782162006549355 8.581588235348019e-08 BR00116993 UNC1999 final compound H19 A549 24 471 Prometaphase +0.1706856456118993 1.1274907942284137e-07 BR00116992 NVP-HSP990 final compound E23 A549 24 565 Prometaphase +0.19301247152794093 1.175531801335898e-07 BR00116994 AZD7762 final compound I05 A549 24 443 Prometaphase +0.25846768730524317 1.3157164330289378e-07 BR00116994 LDN-212854 final compound K01 A549 24 244 Prometaphase +0.10965278420252031 1.3188447064450483e-07 BR00116993 PP-2 final compound J10 A549 24 1364 Prometaphase +0.1888476698353814 1.4377152344350387e-07 BR00116993 CYT-997 final compound E06 A549 24 456 Prometaphase +0.11904067604515986 1.472766601162302e-07 BR00116991 AC-710 final compound I03 A549 24 1154 Prometaphase +0.1464781681250272 1.9473853197510425e-07 BR00116992 geldanamycin final compound L01 A549 24 741 Prometaphase +0.17647058823529413 2.3660437022635014e-07 BR00116991 TG-02 final compound L21 A549 24 510 Prometaphase +0.11775043936731107 2.726441277161462e-07 BR00116992 cediranib final compound L16 A549 24 1138 Prometaphase +0.22082018927444794 3.492648839076217e-07 BR00116994 NSC-632839 final compound M16 A549 24 317 Prometaphase +0.11352253756260434 3.839445111647815e-07 BR00116991 PP-2 final compound J10 A549 24 1198 Prometaphase +0.13214947825626358 4.542564793471644e-07 BR00116993 NSC-663284 final compound G06 A549 24 868 Prometaphase 0.6092539579934538 3.3404272611573625e-153 BR00116992 AMG900 final compound N09 A549 24 882 SmallIrregular 0.6125193787479992 5.342382463260017e-140 BR00116994 AMG900 final compound N09 A549 24 798 SmallIrregular 0.60359005479187 9.787732784537598e-129 BR00116991 AMG900 final compound N09 A549 24 753 SmallIrregular @@ -149,6 +1409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5594125500667557 2.974485088854783e-108 BR00116992 PF-431396 final compound L20 A549 24 749 SmallIrregular 0.4477181767909196 7.586844487744656e-103 BR00116991 polydatin final compound K08 A549 24 1132 SmallIrregular 0.3966757663933454 2.0957365366302996e-100 BR00116994 polydatin final compound K08 A549 24 1421 SmallIrregular +0.43227050790734345 1.9974319189675764e-99 BR00116993 polydatin final compound K08 A549 24 1177 SmallIrregular +0.5787673092587564 5.022588683526281e-99 BR00116993 danusertib final compound E05 A549 24 638 SmallIrregular +0.5752803237129486 2.4891237917394354e-98 BR00116991 danusertib final compound N18 A549 24 641 SmallIrregular +0.5349353238174226 7.089822296982215e-98 BR00116994 PF-431396 final compound L20 A549 24 744 SmallIrregular +0.5742794940908148 8.58731480700327e-98 BR00116994 danusertib final compound N18 A549 24 636 SmallIrregular +0.5564803396155485 8.518462472585563e-95 BR00116993 PF-431396 final compound L20 A549 24 659 SmallIrregular +0.561624307005544 1.4141002464457382e-94 BR00116994 BI-2536 final compound I14 A549 24 645 SmallIrregular +0.5098037162680962 5.2894155761541745e-90 BR00116993 danusertib final compound N18 A549 24 758 SmallIrregular +0.5446612474253605 1.3132625895865807e-86 BR00116994 danusertib final compound E05 A549 24 633 SmallIrregular +0.41332116788321166 3.4445202443349067e-84 BR00116991 quinine final compound A05 A549 24 1096 SmallIrregular +0.5098543183747903 1.7472985746975558e-82 BR00116993 GSK1070916 final compound C04 A549 24 694 SmallIrregular +0.5027102519428082 1.7803396324529946e-82 BR00116994 GSK1070916 final compound C04 A549 24 709 SmallIrregular +0.5305916305916306 2.003644711988509e-81 BR00116993 BI-2536 final compound I14 A549 24 630 SmallIrregular +0.5368864426483309 6.024701733892282e-80 BR00116992 danusertib final compound N18 A549 24 603 SmallIrregular +0.5211505922165821 1.2608894943443957e-73 BR00116992 BI-2536 final compound I14 A549 24 591 SmallIrregular +0.4777176273664361 1.1544146051876474e-71 BR00116992 GSK1070916 final compound C04 A549 24 685 SmallIrregular +0.44606051675017194 1.1667318948120221e-70 BR00116994 geldanamycin final compound L01 A549 24 780 SmallIrregular +0.3588709023483112 2.7941982192119487e-70 BR00116992 ingenol-mebutate final compound M11 A549 24 1217 SmallIrregular +0.5186301711805988 4.642955381537118e-69 BR00116991 BI-2536 final compound I14 A549 24 557 SmallIrregular +0.495 4.088718124660547e-67 BR00116992 danusertib final compound E05 A549 24 600 SmallIrregular +0.4940622440622441 3.4039341910032026e-66 BR00116991 BI-2536 final compound E21 A549 24 594 SmallIrregular +0.3753609239653513 1.4901854310196523e-65 BR00116994 ingenol-mebutate final compound M11 A549 24 1039 SmallIrregular +0.47385103011093505 1.9332189594901172e-64 BR00116991 danusertib final compound E05 A549 24 631 SmallIrregular +0.28345042186985475 2.216603597475297e-63 BR00116993 LY2109761 final compound M02 A549 24 1777 SmallIrregular +0.48594019861830745 1.5428595160784313e-62 BR00116994 BI-2536 final compound E21 A549 24 576 SmallIrregular +0.27807214404939085 1.5973757089688934e-62 BR00116992 LY2109761 final compound M02 A549 24 1822 SmallIrregular +0.44390831008260845 1.2372326707850103e-60 BR00116993 aminopurvalanol-a final compound K03 A549 24 675 SmallIrregular +0.4121545153559038 3.6566842029737126e-59 BR00116994 aminopurvalanol-a final compound K03 A549 24 769 SmallIrregular +0.42496160106370784 5.253936682691501e-59 BR00116991 GSK1070916 final compound C04 A549 24 724 SmallIrregular +0.4758069506670957 9.75365891501482e-59 BR00116992 BI-2536 final compound E21 A549 24 568 SmallIrregular +0.4966453855162253 2.5347910655928974e-58 BR00116993 BI-2536 final compound E21 A549 24 514 SmallIrregular +0.41001437224104303 6.512948868931151e-58 BR00116991 NSC-663284 final compound G06 A549 24 765 SmallIrregular +0.4216778607745904 1.625935968234437e-57 BR00116994 ganetespib final compound M10 A549 24 712 SmallIrregular +0.47802942537487325 1.6292386159743284e-57 BR00116994 PHA-793887 final compound E13 A549 24 553 SmallIrregular +0.4808313155770783 1.9968363620807712e-56 BR00116992 ixabepilone final compound J21 A549 24 531 SmallIrregular +0.3273000431396658 2.5781949742239046e-55 BR00116991 AC-710 final compound I03 A549 24 1154 SmallIrregular +0.4060935527404118 2.579064346677454e-55 BR00116992 geldanamycin final compound L01 A549 24 741 SmallIrregular +0.43070090705619035 6.504599704956441e-55 BR00116993 ganetespib final compound I17 A549 24 650 SmallIrregular +0.2696252465483235 1.5564548832654701e-54 BR00116994 LY2109761 final compound M02 A549 24 1690 SmallIrregular +0.37860455918308644 8.889023874557942e-53 BR00116994 fludarabine-phosphate final compound N12 A549 24 816 SmallIrregular +0.43081414339376123 1.1862670681298233e-52 BR00116993 PHA-793887 final compound I06 A549 24 628 SmallIrregular +0.4145323362217443 4.440016989755752e-52 BR00116991 NVP-HSP990 final compound E23 A549 24 668 SmallIrregular +0.39588763179718045 6.416442963016616e-52 BR00116991 geldanamycin final compound L01 A549 24 736 SmallIrregular +0.34810126582278483 2.4008605965550087e-51 BR00116993 ingenol-mebutate final compound M11 A549 24 948 SmallIrregular +0.4400867787298466 5.515819000945254e-50 BR00116992 NVP-HSP990 final compound E23 A549 24 565 SmallIrregular +0.42707466736645805 1.054983630136345e-49 BR00116992 PHA-793887 final compound I06 A549 24 598 SmallIrregular +0.403017509409262 1.303261950271992e-49 BR00116994 ganetespib final compound I17 A549 24 679 SmallIrregular +0.42032121183511406 1.3342000700481405e-49 BR00116993 NVP-HSP990 final compound E23 A549 24 618 SmallIrregular +0.4578628941568081 2.674026550186011e-49 BR00116993 PHA-793887 final compound E13 A549 24 517 SmallIrregular +0.32153434109582824 2.131078102332317e-48 BR00116991 ingenol-mebutate final compound M11 A549 24 1050 SmallIrregular +0.473866090712743 1.3995451456343345e-47 BR00116991 ixabepilone final compound J21 A549 24 463 SmallIrregular +0.4224401985858282 1.0662140247515592e-46 BR00116994 epothilone-b final compound F07 A549 24 575 SmallIrregular +0.3750505669274957 1.3220963425946863e-45 BR00116992 aminopurvalanol-a final compound K03 A549 24 723 SmallIrregular +0.4411704773951457 3.6808069791271877e-45 BR00116994 NVP-HSP990 final compound E23 A549 24 511 SmallIrregular +0.39652448657187994 8.002847412315913e-45 BR00116991 ganetespib final compound M10 A549 24 633 SmallIrregular +0.40764607350477877 9.207146582581062e-45 BR00116993 epothilone-b final compound F07 A549 24 597 SmallIrregular +0.366713006728577 2.3347710927115894e-44 BR00116991 fludarabine-phosphate final compound N12 A549 24 735 SmallIrregular +0.45689655172413796 4.826323435475737e-44 BR00116994 ixabepilone final compound J21 A549 24 464 SmallIrregular +0.39767961452529005 1.7969677345387325e-43 BR00116994 TG-02 final compound L21 A549 24 610 SmallIrregular +0.380127761802497 3.0285751419834736e-43 BR00116993 ganetespib final compound M10 A549 24 662 SmallIrregular +0.3630217519106408 4.2437718597312945e-43 BR00116992 ganetespib final compound I17 A549 24 729 SmallIrregular +0.43636363636363634 1.0072841781291793e-42 BR00116992 PHA-793887 final compound E13 A549 24 495 SmallIrregular +0.3081357048748353 5.143313146957784e-41 BR00116991 azeliragon final compound C08 A549 24 968 SmallIrregular +0.32325590972737006 5.1711750012296265e-40 BR00116992 azeliragon final compound C08 A549 24 855 SmallIrregular +0.45211910454249077 5.648364997295e-40 BR00116991 oxibendazole final compound M19 A549 24 428 SmallIrregular +0.34174236387782203 1.6741968378971472e-39 BR00116993 fludarabine-phosphate final compound N12 A549 24 753 SmallIrregular +0.4222580067990696 2.3800219286779706e-39 BR00116994 PHA-793887 final compound I06 A549 24 483 SmallIrregular +0.47349629599172166 3.684769992443548e-39 BR00116993 ixabepilone final compound J21 A549 24 383 SmallIrregular +0.4225183211192538 1.8845847666678444e-38 BR00116992 oxibendazole final compound M19 A549 24 475 SmallIrregular +0.4351960614077199 2.1817618845710592e-38 BR00116991 PHA-793887 final compound E13 A549 24 442 SmallIrregular +0.24524803398141395 2.4782585097071614e-38 BR00116994 AC-710 final compound I03 A549 24 1430 SmallIrregular +0.3694488021632928 9.245110105870359e-37 BR00116991 UNC2025 final compound N06 A549 24 597 SmallIrregular +0.38956600859095625 1.5508056605519518e-36 BR00116993 TG-02 final compound L21 A549 24 531 SmallIrregular +0.3597833704344958 1.7446237871946952e-36 BR00116992 ganetespib final compound M10 A549 24 622 SmallIrregular +0.38278388278388276 4.8814878520914726e-36 BR00116994 briciclib final compound H01 A549 24 546 SmallIrregular +0.39341085271317827 4.9952777254497215e-36 BR00116992 TG-02 final compound L21 A549 24 516 SmallIrregular +0.40918948471456557 9.322712326858499e-36 BR00116993 briciclib final compound H01 A549 24 467 SmallIrregular +0.3242284196547145 1.4878229933434024e-35 BR00116993 azeliragon final compound C08 A549 24 753 SmallIrregular +0.39032794380481317 9.083386219428638e-34 BR00116992 briciclib final compound H01 A549 24 490 SmallIrregular +0.3270607939606283 1.2178077782377254e-33 BR00116992 fludarabine-phosphate final compound N12 A549 24 697 SmallIrregular +0.3148148148148148 1.6740034358486558e-33 BR00116994 azeliragon final compound C08 A549 24 756 SmallIrregular +0.39691464622044165 2.8983667194312017e-33 BR00116993 oxibendazole final compound M19 A549 24 465 SmallIrregular +0.21763469624870926 1.0444789745618567e-32 BR00116993 AC-710 final compound I03 A549 24 1556 SmallIrregular +0.2292347421919595 1.5218067590419262e-31 BR00116992 AC-710 final compound I03 A549 24 1351 SmallIrregular +0.36666666666666664 7.051460040439532e-31 BR00116991 TG-02 final compound L21 A549 24 510 SmallIrregular +0.33514384039778083 4.9105377431770074e-29 BR00116991 ganetespib final compound I17 A549 24 571 SmallIrregular +0.38461538461538464 1.1259898915594183e-28 BR00116992 colchicine final compound K17 A549 24 429 SmallIrregular +0.34990629031342035 1.4945441448932474e-27 BR00116991 epothilone-b final compound F07 A549 24 494 SmallIrregular +0.19386864733787382 2.0367073763692074e-27 BR00116991 CC-401 final compound M09 A549 24 1643 SmallIrregular +0.3224179729793344 2.7193117425458406e-27 BR00116993 UNC2025 final compound N06 A549 24 582 SmallIrregular 0.3484983924395947 1.1377006261048528e-69 BR00117016 ingenol-mebutate final compound M11 A549 48 1280 ADCCM 0.7003554923569143 1.2375449429871431e-68 BR00117051 fludarabine-phosphate final compound N12 A549 48 290 ADCCM 0.5537652742256323 3.6404600451260947e-65 BR00117015 fludarabine-phosphate final compound N12 A549 48 459 ADCCM @@ -159,6 +1509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5033895541163863 6.671724702214983e-59 BR00117017 fludarabine-phosphate final compound N12 A549 48 507 ADCCM 0.5318108025097626 5.111393339966488e-56 BR00117016 fludarabine-phosphate final compound N12 A549 48 428 ADCCM 0.6289678940685652 1.6253266199822292e-55 BR00117050 fludarabine-phosphate final compound N12 A549 48 296 ADCCM +0.2797843854126631 3.2156615969820534e-55 BR00117019 fludarabine final compound B06 A549 48 1588 ADCCM +0.2483774627224223 4.551641162901248e-55 BR00117019 desonide final compound E16 A549 48 2011 ADCCM +0.27787605636260315 1.5047480494527286e-54 BR00117015 dexamethasone final compound A21 A549 48 1587 ADCCM +0.24988017951287525 6.588572974676844e-54 BR00117015 desonide final compound E16 A549 48 1945 ADCCM +0.2500752549477797 9.566360074578823e-54 BR00117017 desonide final compound E16 A549 48 1938 ADCCM +0.3251229314420804 3.8571282687692534e-53 BR00117019 ingenol-mebutate final compound M11 A549 48 1128 ADCCM +0.6474264705882353 7.78762285261313e-51 BR00117052 fludarabine-phosphate final compound N12 A549 48 255 ADCCM +0.2780694562512045 8.607129252553902e-51 BR00117017 ingenol-mebutate final compound M11 A549 48 1477 ADCCM +0.26442726370480574 3.364720798189855e-50 BR00117015 fludarabine final compound B06 A549 48 1615 ADCCM +0.27050147174377814 1.9975370375193416e-48 BR00117017 NNC-55-0396 final compound A16 A549 48 1491 ADCCM +0.2666421290878925 9.832288788761204e-48 BR00117017 fludarabine final compound B06 A549 48 1509 ADCCM +0.24556757768436602 1.290087909952609e-47 BR00117019 dexamethasone final compound O02 A549 48 1776 ADCCM +0.25888958203368684 1.3186451380551197e-47 BR00117017 dexamethasone final compound A21 A549 48 1603 ADCCM +0.558282208588957 4.1394676966673917e-47 BR00117055 fludarabine-phosphate final compound N12 A549 48 326 ADCCM +0.23476368459256353 4.2419234730538124e-47 BR00117016 desonide final compound E16 A549 48 1932 ADCCM +0.26744186046511625 2.216069602852714e-46 BR00117016 dexamethasone final compound A21 A549 48 1462 ADCCM +0.33405639913232105 5.9137884668443275e-46 BR00117054 ingenol-mebutate final compound M11 A549 48 922 ADCCM +0.3344407530454042 2.5230797419566316e-45 BR00117055 ingenol-mebutate final compound M11 A549 48 906 ADCCM +0.2810802196282197 2.785495305360459e-45 BR00117016 NNC-55-0396 final compound A16 A549 48 1290 ADCCM +0.25448700018647274 1.3008866415982854e-44 BR00117019 dexamethasone final compound A21 A549 48 1548 ADCCM +0.23711640132021147 1.5101529156847809e-44 BR00117015 dexamethasone final compound O02 A549 48 1788 ADCCM +0.5358500494452156 4.531534183408501e-44 BR00117054 fludarabine-phosphate final compound N12 A549 48 331 ADCCM +0.26450917754896086 1.1102682273897628e-43 BR00117019 NNC-55-0396 final compound A16 A549 48 1407 ADCCM +0.5211841753541834 1.3793872437374561e-43 BR00117019 azeliragon final compound C08 A549 48 348 ADCCM +0.395554641957349 1.5568508698295643e-43 BR00117019 aminopurvalanol-a final compound K03 A549 48 618 ADCCM +0.3954542507353245 4.181181867370459e-41 BR00117015 aminopurvalanol-a final compound K03 A549 48 582 ADCCM +0.402072192513369 6.319368409044077e-41 BR00117019 geldanamycin final compound L01 A549 48 560 ADCCM +0.36228960447730024 7.498669794360375e-41 BR00117051 NNC-55-0396 final compound A16 A549 48 694 ADCCM +0.30065450549019224 8.49105864088491e-41 BR00117054 dexamethasone final compound A21 A549 48 1010 ADCCM +0.40425348374253484 1.4772456978658428e-40 BR00117016 geldanamycin final compound L01 A549 48 548 ADCCM +0.3240585320951891 1.6079246354342633e-40 BR00117055 NNC-55-0396 final compound A16 A549 48 859 ADCCM +0.2137505108524004 1.0218947184801337e-39 BR00117016 dexamethasone final compound O02 A549 48 1963 ADCCM +0.25185030123557645 2.0338414280202035e-39 BR00117055 desonide final compound E16 A549 48 1400 ADCCM +0.4914772727272727 6.063302807729002e-39 BR00117015 azeliragon final compound C08 A549 48 352 ADCCM +0.25705915669460383 1.511825124421159e-38 BR00117015 NNC-55-0396 final compound A16 A549 48 1307 ADCCM +0.5423155907600862 3.405923038394959e-38 BR00117051 aminopurvalanol-a final compound K03 A549 48 279 ADCCM +0.37338678780581247 3.6460420527291625e-38 BR00117016 aminopurvalanol-a final compound K03 A549 48 605 ADCCM +0.35157663785917587 8.107690153797056e-38 BR00117050 halopemide final compound F11 A549 48 678 ADCCM +0.2339147970071823 3.2304952799687765e-37 BR00117016 fludarabine final compound B06 A549 48 1533 ADCCM +0.3382108087990441 7.304495017611936e-37 BR00117015 AZ191 final compound I18 A549 48 715 ADCCM +0.4013947823353764 7.3492650360818094e-37 BR00117015 geldanamycin final compound L01 A549 48 505 ADCCM +0.22442924513570067 1.0454232936444998e-36 BR00117016 halopemide final compound F11 A549 48 1638 ADCCM +0.28920559287954983 1.0497826681662091e-35 BR00117055 FK-866 final compound L09 A549 48 956 ADCCM +0.2221198052486396 1.2025196030368612e-35 BR00117019 halopemide final compound F11 A549 48 1630 ADCCM +0.24663978068418002 1.2550699757993232e-35 BR00117054 desonide final compound E16 A549 48 1319 ADCCM +0.2970576558837664 1.4494262517207764e-35 BR00117019 thiostrepton final compound B02 A549 48 901 ADCCM +0.28035538005923 1.8707629861979865e-35 BR00117055 fludarabine final compound B06 A549 48 1013 ADCCM +0.3208431538697067 1.2935759111275029e-34 BR00117050 fludarabine final compound B06 A549 48 751 ADCCM +0.29054671041436486 2.07578636730079e-34 BR00117055 dexamethasone final compound A21 A549 48 914 ADCCM +0.22481012920003515 3.1682510538680863e-34 BR00117055 dexamethasone final compound O02 A549 48 1524 ADCCM +0.3438840192145793 6.062781702715417e-34 BR00117050 NNC-55-0396 final compound A16 A549 48 635 ADCCM +0.36548606368100955 1.3408614989844637e-33 BR00117019 NVP-HSP990 final compound E23 A549 48 555 ADCCM +0.7330831692913385 1.4130755725081134e-33 BR00117053 romidepsin final compound N19 A549 48 127 ADCCM +0.36513175230566536 2.5854132930629278e-33 BR00117017 aminopurvalanol-a final compound K03 A549 48 552 ADCCM +0.23066013621596662 4.938352467803356e-33 BR00117015 halopemide final compound F11 A549 48 1394 ADCCM +0.42053789731051344 8.535482351992569e-33 BR00117015 7-hydroxystaurosporine final compound L04 A549 48 409 ADCCM +0.37533884624756336 1.4096869820693822e-32 BR00117015 NVP-HSP990 final compound E23 A549 48 512 ADCCM +0.31416149766692275 2.3431314581261118e-32 BR00117051 fludarabine final compound B06 A549 48 730 ADCCM +0.4636256911308036 4.817411435526438e-32 BR00117053 aminopurvalanol-a final compound K03 A549 48 324 ADCCM +0.4482758620689655 7.413419157268116e-32 BR00117053 AZ191 final compound I18 A549 48 348 ADCCM +0.5922619047619048 9.737187745116584e-32 BR00117019 NSC-632839 final compound M16 A549 48 192 ADCCM +0.22780837004405285 1.7415107467202298e-31 BR00117017 FK-866 final compound L09 A549 48 1362 ADCCM +0.46279481132075473 2.2913895297405434e-31 BR00117052 AZ191 final compound I18 A549 48 318 ADCCM +0.5463063063063063 3.5734309622427273e-31 BR00117008 fludarabine-phosphate final compound N12 A549 48 222 ADCCM +0.7006694855532065 3.8682439237525493e-31 BR00117055 romidepsin final compound N19 A549 48 132 ADCCM +0.31145251396648044 4.488502855568976e-31 BR00117019 AZ191 final compound I18 A549 48 716 ADCCM +0.40596403774256723 5.947236289857856e-31 BR00117019 7-hydroxystaurosporine final compound L04 A549 48 411 ADCCM +0.311998186998187 8.233256802574646e-31 BR00117016 AZ191 final compound I18 A549 48 704 ADCCM +0.28160919540229884 8.830315537210833e-31 BR00117015 thiostrepton final compound B02 A549 48 870 ADCCM +0.29975539706751314 1.0183573420569787e-30 BR00117017 AZ191 final compound I18 A549 48 762 ADCCM +0.26540251455885816 1.1895905372025657e-30 BR00117054 FK-866 final compound L09 A549 48 974 ADCCM +0.30674002751031637 1.3523683272626143e-30 BR00117053 fludarabine final compound B06 A549 48 727 ADCCM +0.3280757097791798 1.360358489879926e-30 BR00117053 NNC-55-0396 final compound A16 A549 48 634 ADCCM +0.2906175255144987 3.6253515149774544e-30 BR00117054 NNC-55-0396 final compound A16 A549 48 794 ADCCM +0.28259725824902004 4.439299027753581e-30 BR00117017 thiostrepton final compound B02 A549 48 843 ADCCM +0.4 4.7731716897652256e-30 BR00117054 aminopurvalanol-a final compound K03 A549 48 415 ADCCM +0.20963468289379125 9.865926429640604e-30 BR00117015 JTE-607 final compound C14 A549 48 1524 ADCCM +0.2187948350071736 1.2427421409116592e-29 BR00117054 dexamethasone final compound O02 A549 48 1394 ADCCM +0.2072801202838182 1.4109996667385698e-29 BR00117019 FK-866 final compound L09 A549 48 1543 ADCCM +0.4861981912001332 1.76744453014505e-29 BR00117052 geldanamycin final compound L01 A549 48 268 ADCCM +0.3423336734562081 1.8815588081269704e-29 BR00117015 ganetespib final compound I17 A549 48 556 ADCCM +0.44242424242424244 1.9956738004567426e-29 BR00117050 NSC-663284 final compound G06 A549 48 330 ADCCM +0.4172624237140366 2.1736455736616373e-29 BR00117051 AZ191 final compound I18 A549 48 370 ADCCM +0.43233439555224085 2.2159510080487792e-29 BR00117016 azeliragon final compound C08 A549 48 343 ADCCM +0.39667216688547097 2.875595469164996e-29 BR00117055 geldanamycin final compound L01 A549 48 409 ADCCM +0.16789442253289666 3.164367170804163e-29 BR00117016 RKI-1447 final compound J04 A549 48 2336 ADCCM +0.4189180984761095 3.572307826953101e-29 BR00117054 7-hydroxystaurosporine final compound L04 A549 48 364 ADCCM +0.49363144455252916 3.7705743688054366e-29 BR00117017 azeliragon final compound C08 A549 48 257 ADCCM +0.2282505300039517 5.576702387294637e-29 BR00117017 halopemide final compound F11 A549 48 1247 ADCCM +0.4519291388223427 8.529693304053675e-29 BR00117055 7-hydroxystaurosporine final compound L04 A549 48 308 ADCCM 0.662607646982647 1.4318777780618768e-146 BR00117015 AMG900 final compound N09 A549 48 702 Anaphase 0.622208970414013 2.5340174639232027e-144 BR00117019 AMG900 final compound N09 A549 48 795 Anaphase 0.6569986726236726 8.085881076696226e-144 BR00117015 PF-431396 final compound L20 A549 48 702 Anaphase @@ -169,6 +1609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.670293302163749 1.3760390143048435e-116 BR00117015 epothilone-b final compound F07 A549 48 544 Anaphase 0.5760342005756532 5.757523087597468e-116 BR00117017 PF-431396 final compound L20 A549 48 752 Anaphase 0.6660447761194029 5.270406183575236e-113 BR00117017 epothilone-b final compound F07 A549 48 536 Anaphase +0.6277261563882884 2.755071495306092e-110 BR00117055 AMG900 final compound N09 A549 48 593 Anaphase +0.6975798048688074 4.474883082199202e-108 BR00117015 fludarabine-phosphate final compound N12 A549 48 459 Anaphase +0.6032 3.5952734978634966e-106 BR00117016 PF-431396 final compound L20 A549 48 625 Anaphase +0.6590217273136716 1.4009135076260578e-104 BR00117017 fludarabine-phosphate final compound N12 A549 48 507 Anaphase +0.6186812352985811 1.4654757547045972e-103 BR00117015 danusertib final compound E05 A549 48 575 Anaphase +0.611864406779661 2.2707915427004523e-103 BR00117019 epothilone-b final compound F07 A549 48 590 Anaphase +0.6031498002298725 3.1798334307789686e-103 BR00117016 aminopurvalanol-a final compound K03 A549 48 605 Anaphase +0.5813085219864881 1.8584536095864975e-102 BR00117019 danusertib final compound E05 A549 48 650 Anaphase +0.5881007347437884 1.5644122445756042e-99 BR00117019 aminopurvalanol-a final compound K03 A549 48 618 Anaphase +0.5982741242418348 2.1534376442923968e-97 BR00117015 aminopurvalanol-a final compound K03 A549 48 582 Anaphase +0.8141248963147293 2.447281149618926e-97 BR00117051 fludarabine-phosphate final compound N12 A549 48 290 Anaphase +0.5603461437037653 1.902083428135786e-95 BR00117016 danusertib final compound E05 A549 48 657 Anaphase +0.6143583757191695 2.060097040668637e-95 BR00117054 AMG900 final compound N09 A549 48 537 Anaphase +0.6326645553088677 7.990545908352251e-94 BR00117050 AMG900 final compound N09 A549 48 496 Anaphase +0.6768900004387697 8.923522520569967e-94 BR00117016 fludarabine-phosphate final compound N12 A549 48 428 Anaphase +0.5779220409279431 6.781093177741709e-92 BR00117015 danusertib final compound N18 A549 48 592 Anaphase +0.7877970252131326 7.244178086545619e-92 BR00117050 fludarabine-phosphate final compound N12 A549 48 296 Anaphase +0.6441265733224101 1.7849825800564347e-91 BR00117015 CYT-997 final compound C09 A549 48 464 Anaphase +0.8356464460784314 2.4300925447418815e-91 BR00117052 fludarabine-phosphate final compound N12 A549 48 255 Anaphase +0.8163808397397989 1.4301980924485534e-90 BR00117053 fludarabine-phosphate final compound N12 A549 48 267 Anaphase +0.5560821484992101 2.173928171698986e-90 BR00117017 danusertib final compound N18 A549 48 633 Anaphase +0.5907407407407408 9.302497860028554e-88 BR00117016 danusertib final compound N18 A549 48 540 Anaphase +0.35155135775567703 1.849443367432733e-87 BR00117019 fludarabine final compound B06 A549 48 1588 Anaphase +0.36502420991300505 3.300201406222223e-84 BR00117017 FK-866 final compound D08 A549 48 1410 Anaphase +0.3592123979935614 2.2940700269213386e-83 BR00117016 FK-866 final compound D08 A549 48 1443 Anaphase +0.5433283855568424 6.847529377463617e-83 BR00117017 danusertib final compound E05 A549 48 607 Anaphase +0.609170167592718 2.907172266492931e-82 BR00117055 PF-431396 final compound L20 A549 48 471 Anaphase +0.36651766433445626 9.842828118005608e-82 BR00117017 FK-866 final compound L09 A549 48 1362 Anaphase +0.6020833333333333 2.726246116027562e-81 BR00117015 oxibendazole final compound M19 A549 48 480 Anaphase +0.6292295970958633 3.7711444613692884e-79 BR00117052 AMG900 final compound N09 A549 48 424 Anaphase +0.5966530787384682 4.9097909609396347e-79 BR00117016 CYT-997 final compound C09 A549 48 474 Anaphase +0.36562306154800467 7.93889214567891e-79 BR00117015 FK-866 final compound L09 A549 48 1319 Anaphase +0.5709266676282087 1.1816728679167282e-78 BR00117019 CYT-997 final compound C09 A549 48 519 Anaphase +0.5521936758893281 5.790147527325322e-78 BR00117017 aminopurvalanol-a final compound K03 A549 48 552 Anaphase +0.424957873016292 1.030059660153572e-77 BR00117055 FK-866 final compound L09 A549 48 956 Anaphase +0.3283787530811551 1.1456059148794897e-77 BR00117015 fludarabine final compound B06 A549 48 1615 Anaphase +0.5566978193146418 4.599728533983993e-77 BR00117019 danusertib final compound N18 A549 48 535 Anaphase +0.5809789213426644 4.856160040430739e-77 BR00117017 oxibendazole final compound M19 A549 48 490 Anaphase +0.6020525515574442 6.852099089184983e-77 BR00117053 AMG900 final compound N09 A549 48 452 Anaphase +0.5924024353913756 2.2607389769327486e-76 BR00117015 colchicine final compound K17 A549 48 464 Anaphase +0.3368732528518339 2.4804927504418985e-76 BR00117017 fludarabine final compound B06 A549 48 1509 Anaphase +0.6063348416289592 5.066902783439854e-76 BR00117051 AMG900 final compound N09 A549 48 442 Anaphase +0.6257670549882545 8.656330009575813e-76 BR00117053 PF-431396 final compound L20 A549 48 409 Anaphase +0.7426497786961569 1.5377123984201954e-75 BR00117051 aminopurvalanol-a final compound K03 A549 48 279 Anaphase +0.6207553871655221 6.239688018768593e-75 BR00117019 fludarabine-phosphate final compound N12 A549 48 412 Anaphase +0.5988653805639992 7.710433690858177e-75 BR00117016 oxibendazole final compound M19 A549 48 446 Anaphase +0.3304294213125001 1.7369143324610598e-74 BR00117016 fludarabine final compound B06 A549 48 1533 Anaphase +0.6871165644171779 9.566345963402486e-74 BR00117055 fludarabine-phosphate final compound N12 A549 48 326 Anaphase +0.6561226256235935 3.206063849183082e-73 BR00117052 PF-431396 final compound L20 A549 48 359 Anaphase +0.6822313110656669 1.4505192261231908e-72 BR00117053 aminopurvalanol-a final compound K03 A549 48 324 Anaphase +0.46230038921828964 3.426930726594939e-72 BR00117053 FK-866 final compound D08 A549 48 740 Anaphase +0.47043883083208926 4.288645557210111e-72 BR00117051 FK-866 final compound L09 A549 48 712 Anaphase +0.5877599542540705 7.056994934839329e-72 BR00117017 colchicine final compound K17 A549 48 446 Anaphase +0.3586314948041567 7.320028587273911e-72 BR00117015 FK-866 final compound D08 A549 48 1250 Anaphase +0.3224186129908367 1.2521786184946139e-71 BR00117019 FK-866 final compound L09 A549 48 1543 Anaphase +0.6567106994719395 1.4690633934411638e-71 BR00117053 danusertib final compound E05 A549 48 347 Anaphase +0.5895289377251189 2.151520859874648e-71 BR00117016 briciclib final compound H01 A549 48 439 Anaphase +0.6211620434126828 2.224545582651041e-71 BR00117054 epothilone-b final compound F07 A549 48 391 Anaphase +0.6095132539022813 2.3947974867680804e-70 BR00117016 CYT-997 final compound E06 A549 48 401 Anaphase +0.5578281760854374 8.595268435070313e-70 BR00117017 briciclib final compound H01 A549 48 482 Anaphase +0.3287180006168556 1.8061982226284823e-69 BR00117019 FK-866 final compound D08 A549 48 1441 Anaphase +0.5771812080536913 3.4613728036936145e-69 BR00117019 briciclib final compound H01 A549 48 447 Anaphase +0.59049993542337 4.534297056280558e-69 BR00117015 ixabepilone final compound J21 A549 48 423 Anaphase +0.29871670755053464 7.271861164823387e-69 BR00117017 JTE-607 final compound C14 A549 48 1739 Anaphase +0.3427265803503427 9.358004627022305e-69 BR00117016 FK-866 final compound L09 A549 48 1313 Anaphase +0.6564963755296082 5.1891064324472425e-68 BR00117054 fludarabine-phosphate final compound N12 A549 48 331 Anaphase +0.5879518072289157 7.676130672508813e-67 BR00117054 aminopurvalanol-a final compound K03 A549 48 415 Anaphase +0.5801886792452831 2.2461046925016442e-66 BR00117016 colchicine final compound K17 A549 48 424 Anaphase +0.5707762557077626 3.2760516733739196e-66 BR00117015 briciclib final compound H01 A549 48 438 Anaphase +0.5607064017660044 6.260398025291262e-66 BR00117015 CYT-997 final compound E06 A549 48 453 Anaphase +0.5722401717371035 1.0786521961259512e-65 BR00117016 ixabepilone final compound J21 A549 48 431 Anaphase +0.6246498599439776 1.5600163230866177e-65 BR00117051 PF-431396 final compound L20 A549 48 357 Anaphase +0.6892762267555511 5.849553219158468e-65 BR00117052 aminopurvalanol-a final compound K03 A549 48 284 Anaphase +0.5576362256311921 7.425260296950554e-65 BR00117019 CYT-997 final compound E06 A549 48 448 Anaphase +0.5486409155937053 9.43814783775037e-65 BR00117054 PF-431396 final compound L20 A549 48 465 Anaphase +0.43666733125885626 1.1272848201014179e-64 BR00117050 FK-866 final compound L09 A549 48 751 Anaphase +0.5292929292929293 9.161971770914212e-64 BR00117017 CYT-997 final compound C09 A549 48 495 Anaphase +0.6349986593976227 1.04583766212337e-63 BR00117055 epothilone-b final compound F07 A549 48 334 Anaphase +0.5542731312888113 1.6425709230144223e-63 BR00117017 ixabepilone final compound J21 A549 48 446 Anaphase +0.6739617419044603 1.8280357377245733e-63 BR00117053 CYT-997 final compound C09 A549 48 291 Anaphase +0.5776742024033116 3.4182219061246713e-62 BR00117055 aminopurvalanol-a final compound K03 A549 48 401 Anaphase +0.5656324582338902 3.7854292643707614e-62 BR00117017 CYT-997 final compound E06 A549 48 419 Anaphase +0.3021836649932875 8.228919259541895e-62 BR00117015 JTE-607 final compound C14 A549 48 1524 Anaphase +0.6389150943396227 1.1973950538944109e-61 BR00117052 danusertib final compound E05 A549 48 318 Anaphase +0.40479041916167663 1.5156290787140667e-61 BR00117053 FK-866 final compound L09 A549 48 835 Anaphase +0.42169181808849193 2.3427510838178756e-61 BR00117052 FK-866 final compound D08 A549 48 765 Anaphase +0.3742720570909213 3.204931866485054e-61 BR00117054 FK-866 final compound L09 A549 48 974 Anaphase +0.6617044077905134 4.1322354167186314e-61 BR00117053 danusertib final compound N18 A549 48 292 Anaphase +0.6788103201146679 1.3045874848983136e-60 BR00117050 aminopurvalanol-a final compound K03 A549 48 273 Anaphase +0.6455854054460821 2.650276105934303e-60 BR00117051 danusertib final compound E05 A549 48 303 Anaphase 0.45183850505525364 1.0860153125473456e-146 BR00117019 fludarabine final compound B06 A549 48 1588 Apoptosis 0.43357153921026814 3.574091803364557e-137 BR00117015 fludarabine final compound B06 A549 48 1615 Apoptosis 0.4243440045416508 3.59240994394827e-122 BR00117017 fludarabine final compound B06 A549 48 1509 Apoptosis @@ -179,6 +1709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2759512171273144 3.5311520148144106e-98 BR00117019 LY2109761 final compound M02 A549 48 2916 Apoptosis 0.3551768108730134 8.60513096766584e-98 BR00117017 JTE-607 final compound C14 A549 48 1739 Apoptosis 0.8139945491171939 4.773601084783702e-97 BR00117051 fludarabine-phosphate final compound N12 A549 48 290 Apoptosis +0.3672800915874457 6.8210816686752985e-96 BR00117015 dexamethasone final compound A21 A549 48 1587 Apoptosis +0.6793690491860822 9.491656379865343e-95 BR00117016 fludarabine-phosphate final compound N12 A549 48 428 Apoptosis +0.3557757042903237 1.1224216611017964e-94 BR00117016 JTE-607 final compound C14 A549 48 1678 Apoptosis +0.3624454148471616 5.779754049715164e-94 BR00117017 dexamethasone final compound A21 A549 48 1603 Apoptosis +0.3886866200224583 3.106691354581848e-92 BR00117017 FK-866 final compound L09 A549 48 1362 Apoptosis +0.31502160114738126 9.240244476219163e-92 BR00117017 dexamethasone final compound O02 A549 48 2079 Apoptosis +0.440348861976631 4.482268391372993e-90 BR00117054 fludarabine final compound B06 A549 48 1027 Apoptosis +0.4412635735439289 4.6079135498382574e-89 BR00117055 fludarabine final compound B06 A549 48 1013 Apoptosis +0.3686730506155951 9.167867415343202e-89 BR00117016 dexamethasone final compound A21 A549 48 1462 Apoptosis +0.5113093341828607 1.264373455538068e-87 BR00117051 fludarabine final compound B06 A549 48 730 Apoptosis +0.8012446847455718 1.500646009201166e-86 BR00117053 fludarabine-phosphate final compound N12 A549 48 267 Apoptosis +0.29842139387443856 2.239905246611571e-85 BR00117053 LY2109761 final compound M02 A549 48 2161 Apoptosis +0.6522851053753256 1.9621480654778825e-83 BR00117019 fludarabine-phosphate final compound N12 A549 48 412 Apoptosis +0.4965612104539202 8.855127381448064e-82 BR00117053 fludarabine final compound B06 A549 48 727 Apoptosis +0.38107242206235015 1.4274548756958578e-81 BR00117015 FK-866 final compound D08 A549 48 1250 Apoptosis +0.7470977689098495 3.129330556509339e-81 BR00117050 fludarabine-phosphate final compound N12 A549 48 296 Apoptosis +0.49556651213954583 2.7751299237683796e-80 BR00117051 FK-866 final compound L09 A549 48 712 Apoptosis +0.30430337094970444 3.818450994772027e-80 BR00117015 desonide final compound E16 A549 48 1945 Apoptosis +0.7923560049019608 4.259616580085264e-80 BR00117052 fludarabine-phosphate final compound N12 A549 48 255 Apoptosis +0.7017047258739102 8.680592719475029e-79 BR00117054 fludarabine-phosphate final compound N12 A549 48 331 Apoptosis +0.24902551045733123 1.723290157511025e-78 BR00117015 LY2109761 final compound M02 A549 48 2866 Apoptosis +0.4820413953657561 1.740609477873539e-78 BR00117053 FK-866 final compound D08 A549 48 740 Apoptosis +0.426328374888358 2.8213213395145065e-78 BR00117055 FK-866 final compound L09 A549 48 956 Apoptosis +0.4328613439235358 2.909584367445202e-77 BR00117055 dexamethasone final compound A21 A549 48 914 Apoptosis +0.33377251394101687 1.062966590083706e-76 BR00117019 FK-866 final compound L09 A549 48 1543 Apoptosis +0.3472575492737026 6.012900208572764e-76 BR00117017 FK-866 final compound D08 A549 48 1410 Apoptosis +0.2964831831164659 1.6378756930833655e-75 BR00117017 desonide final compound E16 A549 48 1938 Apoptosis +0.46904661876855813 3.864715414762893e-75 BR00117050 fludarabine final compound B06 A549 48 751 Apoptosis +0.3212694973258354 4.013314238166825e-75 BR00117019 JTE-607 final compound C14 A549 48 1638 Apoptosis +0.5426277372262773 1.5390325517832128e-74 BR00117016 geldanamycin final compound L01 A549 48 548 Apoptosis +0.5171692846587488 1.5663388641638452e-74 BR00117016 aminopurvalanol-a final compound K03 A549 48 605 Apoptosis +0.6901840490797546 1.770902519540932e-74 BR00117055 fludarabine-phosphate final compound N12 A549 48 326 Apoptosis +0.40921542060793753 1.5591015779512994e-73 BR00117054 FK-866 final compound L09 A549 48 974 Apoptosis +0.30327369308092816 5.630411357543579e-73 BR00117015 dexamethasone final compound O02 A549 48 1788 Apoptosis +0.33634529479404823 6.578906312344e-73 BR00117016 FK-866 final compound D08 A549 48 1443 Apoptosis +0.5060086651276051 2.839164524493099e-72 BR00117019 aminopurvalanol-a final compound K03 A549 48 618 Apoptosis +0.455849844300722 3.989502382047654e-72 BR00117052 FK-866 final compound D08 A549 48 765 Apoptosis +0.5189681290634413 4.899258729848627e-72 BR00117015 aminopurvalanol-a final compound K03 A549 48 582 Apoptosis +0.32225651988598525 1.0235057711744818e-71 BR00117019 dexamethasone final compound A21 A549 48 1548 Apoptosis +0.447224678259161 6.6981362419524014e-71 BR00117051 JTE-607 final compound C14 A549 48 780 Apoptosis +0.35698772826495734 1.5291716288872481e-68 BR00117055 JTE-607 final compound C14 A549 48 1202 Apoptosis +0.3406460357938751 2.6066547140539055e-68 BR00117015 FK-866 final compound L09 A549 48 1319 Apoptosis +0.32321882951653946 3.2864961953259625e-67 BR00117019 FK-866 final compound D08 A549 48 1441 Apoptosis +0.44362418735803244 7.003085056946408e-67 BR00117050 FK-866 final compound L09 A549 48 751 Apoptosis +0.33663366336633666 2.680098343509458e-66 BR00117016 FK-866 final compound L09 A549 48 1313 Apoptosis +0.4391891891891892 1.560243109796517e-64 BR00117052 fludarabine final compound B06 A549 48 740 Apoptosis +0.3768283468584718 3.0420734738612254e-64 BR00117054 dexamethasone final compound A21 A549 48 1010 Apoptosis +0.42932420686657974 4.781943101309605e-64 BR00117052 FK-866 final compound L09 A549 48 768 Apoptosis +0.2206967786608407 2.006730504342925e-63 BR00117016 LY2109761 final compound M02 A549 48 2954 Apoptosis +0.40838323353293415 1.1400473985412282e-62 BR00117053 FK-866 final compound L09 A549 48 835 Apoptosis +0.2623448866067608 1.271317066212701e-62 BR00117052 LY2109761 final compound M02 A549 48 2052 Apoptosis +0.2213663847523411 5.851305090310128e-62 BR00117017 LY2109761 final compound M02 A549 48 2862 Apoptosis +0.4340643274853801 1.8160492668567748e-61 BR00117050 FK-866 final compound D08 A549 48 722 Apoptosis +0.4879838298955946 3.8011090951291974e-61 BR00117019 geldanamycin final compound L01 A549 48 560 Apoptosis +0.6741412518016812 6.167092345125784e-61 BR00117051 aminopurvalanol-a final compound K03 A549 48 279 Apoptosis +0.5044544956140351 4.5931358412236833e-60 BR00117015 NVP-HSP990 final compound E23 A549 48 512 Apoptosis +0.3611519607843137 7.895686554401429e-60 BR00117055 FK-866 final compound D08 A549 48 1024 Apoptosis +0.26167209729455015 1.534149346744011e-58 BR00117016 desonide final compound E16 A549 48 1932 Apoptosis +0.47982872200263504 4.4474222553529985e-58 BR00117017 aminopurvalanol-a final compound K03 A549 48 552 Apoptosis +0.5469879518072289 2.3928406588437715e-57 BR00117054 aminopurvalanol-a final compound K03 A549 48 415 Apoptosis +0.4314421113263863 2.828159054513214e-57 BR00117051 FK-866 final compound D08 A549 48 676 Apoptosis +0.47866419294990725 2.893525753363429e-56 BR00117009 fludarabine final compound B06 A549 48 539 Apoptosis +0.49254675467546755 5.002513383544103e-56 BR00117015 geldanamycin final compound L01 A549 48 505 Apoptosis +0.28770100799120396 5.298297747659309e-56 BR00117055 dexamethasone final compound O02 A549 48 1524 Apoptosis +0.23434077967586509 2.265487612972544e-55 BR00117055 LY2109761 final compound M02 A549 48 2283 Apoptosis +0.47926694227078104 1.584960140361995e-54 BR00117017 geldanamycin final compound L01 A549 48 520 Apoptosis +0.37341040462427744 4.591407138037053e-54 BR00117053 JTE-607 final compound C14 A549 48 865 Apoptosis +0.23929260365193034 5.805799115103351e-54 BR00117017 PP-2 final compound J10 A549 48 2132 Apoptosis +0.26345440672853415 8.636856140626354e-54 BR00117051 LY2109761 final compound M02 A549 48 1746 Apoptosis +0.35749462955345307 1.6437567352282746e-53 BR00117054 FK-866 final compound D08 A549 48 935 Apoptosis +0.24733980265908087 4.0480983071857265e-53 BR00117016 dexamethasone final compound O02 A549 48 1963 Apoptosis +0.6426649281473672 4.234038149803251e-53 BR00117052 geldanamycin final compound L01 A549 48 268 Apoptosis +0.34545689430682597 4.597418065082335e-53 BR00117054 JTE-607 final compound C14 A549 48 991 Apoptosis +0.590017420283269 5.92601234300793e-53 BR00117053 aminopurvalanol-a final compound K03 A549 48 324 Apoptosis +0.42101650916968586 1.333723400647119e-52 BR00117009 FK-866 final compound D08 A549 48 656 Apoptosis +0.25776021670182253 2.15231334153056e-52 BR00117019 dexamethasone final compound O02 A549 48 1776 Apoptosis +0.4537572814279994 3.0282713449621778e-52 BR00117015 ganetespib final compound I17 A549 48 556 Apoptosis +0.29814786521647635 4.0422711143120376e-52 BR00117054 desonide final compound E16 A549 48 1319 Apoptosis +0.23992494560236788 2.2063182010172593e-51 BR00117019 desonide final compound E16 A549 48 2011 Apoptosis +0.2860778106810987 6.940311579411212e-51 BR00117055 desonide final compound E16 A549 48 1400 Apoptosis +0.36091954022988504 9.656580186869171e-51 BR00117015 thiostrepton final compound B02 A549 48 870 Apoptosis +0.2339996388051308 1.158105698103844e-50 BR00117016 PP-2 final compound J10 A549 48 2093 Apoptosis +0.5143025762703699 8.376533245770344e-50 BR00117055 geldanamycin final compound L01 A549 48 409 Apoptosis +0.2380775608315281 2.36694543123653e-49 BR00117019 PP-2 final compound J10 A549 48 1961 Apoptosis +0.38421578421578423 1.263127266689249e-47 BR00117015 AZ191 final compound I18 A549 48 715 Apoptosis +0.7024489795918367 1.4836190651817049e-47 BR00117009 fludarabine-phosphate final compound N12 A549 48 200 Apoptosis +0.2198758722654124 2.0325703297047524e-47 BR00117054 LY2109761 final compound M02 A549 48 2220 Apoptosis +0.3865295584045584 2.611113753394986e-47 BR00117015 PF-431396 final compound L20 A549 48 702 Apoptosis +0.5137499832643826 2.675514442885464e-47 BR00117054 geldanamycin final compound L01 A549 48 387 Apoptosis +0.20114525267818228 2.811239884836648e-47 BR00117050 CC-401 final compound M09 A549 48 2642 Apoptosis 0.24142888424524486 8.717946433840718e-56 BR00117053 LY2109761 final compound M02 A549 48 2161 Binuclear 0.631768953068592 3.511307735684899e-52 BR00117017 AR-12 final compound C10 A549 48 277 Binuclear 0.5623474793167074 4.635612093604441e-47 BR00117019 AR-12 final compound C10 A549 48 318 Binuclear @@ -189,6 +1809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.22781903142314272 1.2094995040418993e-38 BR00117016 JTE-607 final compound C14 A549 48 1678 Binuclear 0.23853450935179393 1.910299810541376e-38 BR00117015 JTE-607 final compound C14 A549 48 1524 Binuclear 0.20293205914515286 1.7070134761656912e-37 BR00117052 LY2109761 final compound M02 A549 48 2052 Binuclear +0.6225490196078431 2.5913901211008207e-37 BR00117054 AR-12 final compound C10 A549 48 204 Binuclear +0.16904534576008237 3.188378523705532e-36 BR00117015 LY2109761 final compound M02 A549 48 2866 Binuclear +0.6834246297423412 9.842734560106796e-36 BR00117016 romidepsin final compound N19 A549 48 159 Binuclear +0.7485851377952756 3.4894532916084705e-35 BR00117053 romidepsin final compound N19 A549 48 127 Binuclear +0.7398313492063492 3.4263875132854677e-34 BR00117050 romidepsin final compound N19 A549 48 126 Binuclear +0.4751520148407709 2.1343345607920723e-32 BR00117052 oxibendazole final compound M19 A549 48 310 Binuclear +0.21059592264460156 7.002542401018085e-32 BR00117015 fludarabine final compound B06 A549 48 1615 Binuclear +0.720030737704918 8.54586744929324e-32 BR00117019 romidepsin final compound N19 A549 48 122 Binuclear +0.20127047216849725 2.190226655705825e-31 BR00117051 LY2109761 final compound M02 A549 48 1746 Binuclear +0.7010218463706835 3.1625142145173583e-31 BR00117055 romidepsin final compound N19 A549 48 132 Binuclear +0.20093687694010884 3.8616369219644067e-31 BR00117017 JTE-607 final compound C14 A549 48 1739 Binuclear +0.7513037809647979 4.55203676566872e-31 BR00117051 romidepsin final compound N19 A549 48 104 Binuclear +0.3879283458734552 6.9866349089284495e-31 BR00117053 AMG900 final compound N09 A549 48 452 Binuclear +0.6942052165354331 5.817685978149619e-30 BR00117051 AR-12 final compound C10 A549 48 127 Binuclear +0.4569766594865711 1.0549273745711463e-29 BR00117053 oxibendazole final compound M19 A549 48 309 Binuclear +0.13847697850995194 1.194855115477922e-29 BR00117015 CC-401 final compound M09 A549 48 3491 Binuclear +0.1999735312656317 4.312530510350436e-29 BR00117019 JTE-607 final compound C14 A549 48 1638 Binuclear +0.15126232369382378 4.457090950537825e-29 BR00117017 LY2109761 final compound M02 A549 48 2862 Binuclear +0.2035910031792766 1.669107674118854e-28 BR00117019 FK-866 final compound L09 A549 48 1543 Binuclear +0.18086045175886487 1.7905170455513928e-28 BR00117019 PP-2 final compound J10 A549 48 1961 Binuclear +0.6657413832986352 1.986704725906677e-28 BR00117009 AR-12 final compound C10 A549 48 132 Binuclear +0.22010662604722012 2.873968289714303e-28 BR00117016 FK-866 final compound L09 A549 48 1313 Binuclear +0.20895986546956077 3.759454922485187e-28 BR00117016 FK-866 final compound D08 A549 48 1443 Binuclear +0.21790727594366716 5.6577141210627075e-28 BR00117015 FK-866 final compound L09 A549 48 1319 Binuclear +0.6907857546636518 8.867180715845924e-28 BR00117008 AR-12 final compound C10 A549 48 116 Binuclear +0.2235640071662603 9.463287235072754e-27 BR00117055 JTE-607 final compound C14 A549 48 1202 Binuclear +0.6614173228346457 1.3456078200056226e-26 BR00117052 AR-12 final compound C10 A549 48 127 Binuclear +0.37158270963115675 1.6255005886536852e-26 BR00117052 AMG900 final compound N09 A549 48 424 Binuclear +0.20511957722201005 4.0629344044639764e-26 BR00117052 PP-2 final compound J10 A549 48 1390 Binuclear +0.1940417856759643 1.168250500251623e-25 BR00117016 fludarabine final compound B06 A549 48 1533 Binuclear +0.24346206811592289 2.7233053128229674e-25 BR00117055 FK-866 final compound L09 A549 48 956 Binuclear +0.6625132743362832 2.9271799014760145e-25 BR00117052 romidepsin final compound N19 A549 48 113 Binuclear +0.19997589054306553 3.151934553954338e-25 BR00117017 FK-866 final compound D08 A549 48 1410 Binuclear +0.3552036199095023 3.75082817707721e-25 BR00117051 AMG900 final compound N09 A549 48 442 Binuclear +0.23359757965686276 6.3321617718324595e-25 BR00117055 FK-866 final compound D08 A549 48 1024 Binuclear +0.6793766578249337 1.1574247798774353e-24 BR00117053 AR-12 final compound C10 A549 48 104 Binuclear +0.20845083932853717 2.430652958231726e-24 BR00117015 FK-866 final compound D08 A549 48 1250 Binuclear +0.43611421069904827 3.231887920925072e-24 BR00117052 colchicine final compound K17 A549 48 277 Binuclear +0.2607132331270262 6.5284041247870475e-24 BR00117051 JTE-607 final compound C14 A549 48 780 Binuclear +0.1601805517137325 6.807968956911828e-24 BR00117016 PP-2 final compound J10 A549 48 2093 Binuclear +0.4544134727061556 9.454471319353891e-24 BR00117051 oxibendazole final compound M19 A549 48 246 Binuclear +0.14142637579427889 1.6843514010751395e-23 BR00117050 CC-401 final compound M09 A549 48 2642 Binuclear +0.445570890077821 2.23251113080266e-23 BR00117050 colchicine final compound K17 A549 48 256 Binuclear +0.6292372881355932 2.2446714923714868e-23 BR00117017 romidepsin final compound N19 A549 48 118 Binuclear +0.19598881402781376 2.5882302566966462e-23 BR00117017 FK-866 final compound L09 A549 48 1362 Binuclear +0.680672268907563 2.74560193130343e-23 BR00117054 romidepsin final compound N19 A549 48 102 Binuclear +0.32212354708110225 2.863760247374571e-23 BR00117050 AMG900 final compound N09 A549 48 496 Binuclear +0.21041844577284372 3.948940566396347e-23 BR00117019 polydatin final compound K08 A549 48 1170 Binuclear +0.29682256978223454 5.614643976412809e-23 BR00117052 polydatin final compound K08 A549 48 575 Binuclear +0.20832360723476748 7.236538492727641e-23 BR00117017 polydatin final compound K08 A549 48 1175 Binuclear +0.60814468503937 1.0934137139513078e-22 BR00117015 romidepsin final compound N19 A549 48 127 Binuclear +0.4350886572217767 1.1109750287446805e-22 BR00117050 oxibendazole final compound M19 A549 48 258 Binuclear +0.17660896255371394 1.142225855474795e-22 BR00117050 LY2109761 final compound M02 A549 48 1625 Binuclear +0.4065772961307953 4.511676685419466e-22 BR00117053 CYT-997 final compound C09 A549 48 291 Binuclear +0.4197080291970803 5.221814670033989e-22 BR00117051 colchicine final compound K17 A549 48 274 Binuclear +0.11776223776223776 5.27969302104378e-22 BR00117019 CC-401 final compound M09 A549 48 3575 Binuclear +0.1471747700394218 5.641548933489788e-22 BR00117055 LY2109761 final compound M02 A549 48 2283 Binuclear +0.1795491153939007 1.1007022813462677e-21 BR00117017 fludarabine final compound B06 A549 48 1509 Binuclear +0.5048192031432255 1.8202993384055503e-21 BR00117055 AR-12 final compound C10 A549 48 179 Binuclear +0.6479208646272211 1.9035353655258975e-21 BR00117050 AR-12 final compound C10 A549 48 106 Binuclear +0.14715107352618623 2.0037025433698886e-21 BR00117054 LY2109761 final compound M02 A549 48 2220 Binuclear +0.17313092201600275 3.2124446149204898e-21 BR00117019 fludarabine final compound B06 A549 48 1588 Binuclear +0.247074122236671 5.1817871567306074e-21 BR00117017 AMG900 final compound N09 A549 48 769 Binuclear +0.796875 1.7678429968489476e-20 BR00117008 romidepsin final compound N19 A549 48 64 Binuclear +0.17091428022920346 2.1766637467744002e-20 BR00117015 deferasirox final compound L14 A549 48 1557 Binuclear +0.17802403809083198 2.230125366646529e-20 BR00117019 FK-866 final compound D08 A549 48 1441 Binuclear +0.5652573529411765 5.413630271543484e-20 BR00117017 TG-101348 final compound M20 A549 48 136 Binuclear +0.2368453275449435 5.458209025956455e-20 BR00117019 AMG900 final compound N09 A549 48 795 Binuclear +0.2176230632112985 5.629785881842366e-20 BR00117054 FK-866 final compound D08 A549 48 935 Binuclear +0.4006263616557734 5.637085023495492e-20 BR00117050 PF-431396 final compound L20 A549 48 270 Binuclear +0.34220054200542005 7.333282500435732e-20 BR00117019 PP-121 final compound B16 A549 48 369 Binuclear +0.4052426811047501 1.037534083775845e-19 BR00117053 colchicine final compound K17 A549 48 261 Binuclear +0.11041608588480338 2.0593247622495244e-19 BR00117016 CC-401 final compound M09 A549 48 3567 Binuclear +0.40784313725490196 2.3525766564604677e-19 BR00117051 ixabepilone final compound J21 A549 48 255 Binuclear +0.11094080757755938 4.273888714631644e-19 BR00117017 CC-401 final compound M09 A549 48 3481 Binuclear +0.14590879278891916 1.1912935967374451e-18 BR00117015 PP-2 final compound J10 A549 48 1962 Binuclear +0.32698950174064406 1.4174079391597215e-18 BR00117016 PP-121 final compound B16 A549 48 383 Binuclear +0.20138203356367226 2.2169989143883983e-18 BR00117055 fludarabine final compound B06 A549 48 1013 Binuclear +0.25942268799411655 5.714540176627343e-18 BR00117051 polydatin final compound K08 A549 48 588 Binuclear +0.3976958525345622 5.780794407058477e-18 BR00117053 briciclib final compound H01 A549 48 245 Binuclear +0.15590009122234247 5.968313099424216e-18 BR00117054 PP-2 final compound J10 A549 48 1645 Binuclear +0.5667447306791569 6.867216351820888e-18 BR00117019 TG-101348 final compound M20 A549 48 112 Binuclear +0.3077688288029148 1.065514985311375e-17 BR00117053 PF-431396 final compound L20 A549 48 409 Binuclear +0.25518917573027605 1.4543199958192925e-17 BR00117055 AMG900 final compound N09 A549 48 593 Binuclear +0.19976141986737134 1.802070951029863e-17 BR00117054 FK-866 final compound L09 A549 48 974 Binuclear +0.2378689497477789 2.5296216604117472e-17 BR00117051 FK-866 final compound D08 A549 48 676 Binuclear +0.31430863794604 2.5430550954036747e-17 BR00117017 PP-121 final compound B16 A549 48 383 Binuclear +0.21566265060240963 2.59173629135257e-17 BR00117008 PP-2 final compound J10 A549 48 830 Binuclear +0.7191964285714286 2.7354803686854055e-17 BR00117009 romidepsin final compound N19 A549 48 70 Binuclear +0.16256765470304624 2.748165989201778e-17 BR00117055 PP-2 final compound J10 A549 48 1457 Binuclear 0.5162548764629389 8.13820403699493e-94 BR00117017 AMG900 final compound N09 A549 48 769 Elongated 0.513419450919451 7.309808172687497e-85 BR00117015 AMG900 final compound N09 A549 48 702 Elongated 0.48200112905405945 3.7328138767227356e-84 BR00117019 AMG900 final compound N09 A549 48 795 Elongated @@ -199,6 +1909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5656108597285068 1.5513307421632144e-65 BR00117051 AMG900 final compound N09 A549 48 442 Elongated 0.5008392682396433 1.3528704737794907e-62 BR00117015 epothilone-b final compound F07 A549 48 544 Elongated 0.5451152001871272 3.498803591087934e-62 BR00117053 AMG900 final compound N09 A549 48 452 Elongated +0.4365247021497021 1.2933721931738908e-60 BR00117015 PF-431396 final compound L20 A549 48 702 Elongated +0.6306709265175718 1.5058566092517297e-58 BR00117052 oxibendazole final compound M19 A549 48 310 Elongated +0.4832089552238806 4.619781533691705e-57 BR00117017 epothilone-b final compound F07 A549 48 536 Elongated +0.6193508777406632 4.130886895755283e-56 BR00117053 oxibendazole final compound M19 A549 48 309 Elongated +0.4771341888687404 9.978004713005891e-56 BR00117016 epothilone-b final compound F07 A549 48 535 Elongated +0.5082483056527891 2.582303663562239e-55 BR00117015 colchicine final compound K17 A549 48 464 Elongated +0.4909090909090909 1.7437168202136293e-54 BR00117017 CYT-997 final compound C09 A549 48 495 Elongated +0.6249081644744638 6.22933955676674e-54 BR00117051 fludarabine-phosphate final compound N12 A549 48 290 Elongated +0.5117474744434747 8.878203857092554e-54 BR00117016 oxibendazole final compound M19 A549 48 446 Elongated +0.5100671140939598 2.5352716505128797e-53 BR00117019 briciclib final compound H01 A549 48 447 Elongated +0.49166666666666664 5.150127916353525e-53 BR00117015 oxibendazole final compound M19 A549 48 480 Elongated +0.5005316961105928 2.5557841735849086e-51 BR00117017 colchicine final compound K17 A549 48 446 Elongated +0.4863047986841164 2.6738657743705986e-51 BR00117016 CYT-997 final compound C09 A549 48 474 Elongated +0.39777468706536856 3.4546668180523954e-51 BR00117019 PF-431396 final compound L20 A549 48 719 Elongated +0.6235247784706268 4.65711104631513e-51 BR00117052 colchicine final compound K17 A549 48 277 Elongated +0.5935483870967742 7.468585203076132e-51 BR00117052 briciclib final compound H01 A549 48 305 Elongated +0.6288473993973698 2.6690506660079657e-50 BR00117053 fludarabine-phosphate final compound N12 A549 48 267 Elongated +0.6024770416241512 1.013612202529333e-49 BR00117053 CYT-997 final compound C09 A549 48 291 Elongated +0.47256752443474437 2.38516066859951e-49 BR00117017 briciclib final compound H01 A549 48 482 Elongated +0.5025690268021091 3.3140188909312074e-49 BR00117015 ixabepilone final compound J21 A549 48 423 Elongated +0.3000790364227884 1.270529067735618e-48 BR00117015 polydatin final compound K08 A549 48 1211 Elongated +0.6293326205114497 1.2839885774872717e-48 BR00117050 oxibendazole final compound M19 A549 48 258 Elongated +0.5385819132122123 2.6906023594008787e-48 BR00117055 briciclib final compound H01 A549 48 358 Elongated +0.6172594407366732 5.894434052702347e-48 BR00117053 CYT-997 final compound E06 A549 48 267 Elongated +0.6353077816492451 6.83668168534859e-48 BR00117051 oxibendazole final compound M19 A549 48 246 Elongated +0.48123620309050774 7.102270452896306e-48 BR00117015 CYT-997 final compound E06 A549 48 453 Elongated +0.47370037983168245 8.381888009741173e-48 BR00117015 CYT-997 final compound C09 A549 48 464 Elongated +0.6279718137254902 1.4230035153154e-47 BR00117052 fludarabine-phosphate final compound N12 A549 48 255 Elongated +0.29937873790278735 4.566105818447546e-47 BR00117017 polydatin final compound K08 A549 48 1175 Elongated +0.45776306415790136 7.676584634335222e-47 BR00117017 oxibendazole final compound M19 A549 48 490 Elongated +0.6156156156156156 9.342335006365934e-47 BR00117053 colchicine final compound K17 A549 48 261 Elongated +0.37156442237146564 1.028262292231764e-46 BR00117017 PF-431396 final compound L20 A549 48 752 Elongated +0.4186440677966102 1.0498527016048734e-46 BR00117019 epothilone-b final compound F07 A549 48 590 Elongated +0.48178979686514495 1.2188837877440087e-46 BR00117016 briciclib final compound H01 A549 48 439 Elongated +0.4440031213133185 1.5147818309958035e-46 BR00117019 CYT-997 final compound C09 A549 48 519 Elongated +0.4916467780429594 2.5500225109007475e-46 BR00117017 CYT-997 final compound E06 A549 48 419 Elongated +0.6298551678736011 2.5620674857299477e-46 BR00117053 briciclib final compound H01 A549 48 245 Elongated +0.4462874093401047 5.552634417675759e-46 BR00117017 fludarabine-phosphate final compound N12 A549 48 507 Elongated +0.49850066192543335 5.61144188301821e-46 BR00117016 CYT-997 final compound E06 A549 48 401 Elongated +0.4666666666666667 1.3444617443763924e-45 BR00117015 fludarabine-phosphate final compound N12 A549 48 459 Elongated +0.42988270935823675 3.201800017894411e-45 BR00117054 AMG900 final compound N09 A549 48 537 Elongated +0.4785545460459267 4.066035761154891e-45 BR00117016 ixabepilone final compound J21 A549 48 431 Elongated +0.47877358490566035 2.3244541351949045e-44 BR00117016 colchicine final compound K17 A549 48 424 Elongated +0.4615542106104187 9.578673776719249e-44 BR00117019 CYT-997 final compound E06 A549 48 448 Elongated +0.3979858792622188 1.7744158254073163e-43 BR00117016 aminopurvalanol-a final compound K03 A549 48 605 Elongated +0.5985074173151751 2.3553515024819625e-43 BR00117050 colchicine final compound K17 A549 48 256 Elongated +0.40582247293003954 2.5712281602451522e-43 BR00117015 aminopurvalanol-a final compound K03 A549 48 582 Elongated +0.5585661164520225 4.594924798202664e-43 BR00117050 fludarabine-phosphate final compound N12 A549 48 296 Elongated +0.526092750533049 5.513239307321491e-43 BR00117055 CYT-997 final compound E06 A549 48 336 Elongated +0.21186685324877833 5.8931533773294294e-43 BR00117053 LY2109761 final compound M02 A549 48 2161 Elongated +0.5693649529686956 8.461363247655326e-43 BR00117050 epothilone-b final compound F07 A549 48 283 Elongated +0.4454307268374215 9.319269913254628e-43 BR00117055 PF-431396 final compound L20 A549 48 471 Elongated +0.47689075630252103 1.319928986711062e-42 BR00117019 oxibendazole final compound M19 A549 48 408 Elongated +0.5766423357664233 1.8615775918623402e-42 BR00117051 colchicine final compound K17 A549 48 274 Elongated +0.4611872146118721 2.0980615464624194e-42 BR00117015 briciclib final compound H01 A549 48 438 Elongated +0.3885972402306484 4.323616872461268e-42 BR00117019 aminopurvalanol-a final compound K03 A549 48 618 Elongated +0.6074380165289256 6.213461050435393e-42 BR00117008 briciclib final compound H01 A549 48 242 Elongated +0.27421167703393484 9.658257547350254e-42 BR00117016 polydatin final compound K08 A549 48 1248 Elongated +0.6154984827177855 1.0877556269971158e-41 BR00117050 CYT-997 final compound E06 A549 48 236 Elongated +0.452914798206278 1.3608588937513873e-41 BR00117019 colchicine final compound K17 A549 48 446 Elongated +0.5882352941176471 3.050907540796213e-41 BR00117051 ixabepilone final compound J21 A549 48 255 Elongated +0.44907254140708863 4.028704638006676e-41 BR00117017 ixabepilone final compound J21 A549 48 446 Elongated +0.5441516464276897 6.150221442951414e-41 BR00117052 epothilone-b final compound F07 A549 48 298 Elongated +0.5155241755295379 6.295174572161596e-41 BR00117055 epothilone-b final compound F07 A549 48 334 Elongated +0.5048225567952682 9.299476969573021e-41 BR00117009 AMG900 final compound N09 A549 48 346 Elongated +0.5675925925925925 1.0306940843230476e-40 BR00117050 PF-431396 final compound L20 A549 48 270 Elongated +0.5382560706401766 1.5791818891332503e-40 BR00117051 epothilone-b final compound F07 A549 48 300 Elongated +0.2779544110884845 3.051413168212056e-40 BR00117019 polydatin final compound K08 A549 48 1170 Elongated +0.17663217470983208 1.7825680273143335e-39 BR00117017 LY2109761 final compound M02 A549 48 2862 Elongated +0.5406563933091466 1.9257867718225948e-39 BR00117052 CYT-997 final compound C09 A549 48 291 Elongated +0.5497901758951007 2.5913359860795106e-39 BR00117051 aminopurvalanol-a final compound K03 A549 48 279 Elongated +0.44743539116317843 4.0342834905890544e-39 BR00117016 fludarabine-phosphate final compound N12 A549 48 428 Elongated +0.39400527009222663 7.589170068707776e-39 BR00117017 aminopurvalanol-a final compound K03 A549 48 552 Elongated +0.5735555555555556 1.3455880217967454e-38 BR00117050 briciclib final compound H01 A549 48 252 Elongated +0.5775899875181324 3.198168716239273e-38 BR00117051 briciclib final compound H01 A549 48 241 Elongated +0.5443546277402815 3.3798123355633647e-38 BR00117051 CYT-997 final compound C09 A549 48 277 Elongated +0.5365733731868587 1.952216603018431e-37 BR00117052 ixabepilone final compound J21 A549 48 279 Elongated +0.3720694410643303 6.951286573446408e-37 BR00117053 polydatin final compound K08 A549 48 588 Elongated +0.5046292043076609 9.094530605077828e-37 BR00117055 colchicine final compound K17 A549 48 311 Elongated +0.3616 1.0549260904880192e-36 BR00117016 PF-431396 final compound L20 A549 48 625 Elongated +0.4945656290237067 1.4060351634411515e-36 BR00117053 aminopurvalanol-a final compound K03 A549 48 324 Elongated +0.5318280275680998 3.5365099115821115e-36 BR00117050 CYT-997 final compound C09 A549 48 275 Elongated +0.5661723163841808 1.1566912562688738e-35 BR00117052 CYT-997 final compound E06 A549 48 236 Elongated +0.22170127969022996 1.7000394261650755e-35 BR00117050 LY2109761 final compound M02 A549 48 1625 Elongated +0.2138312700975724 2.0524783747632073e-35 BR00117051 LY2109761 final compound M02 A549 48 1746 Elongated +0.19698759092854087 2.655189750223483e-35 BR00117052 LY2109761 final compound M02 A549 48 2052 Elongated +0.4634106038430669 4.563689839548257e-35 BR00117052 PF-431396 final compound L20 A549 48 359 Elongated +0.4323373603720217 5.115655915716423e-35 BR00117053 PF-431396 final compound L20 A549 48 409 Elongated +0.53325651735561 7.51960514221311e-35 BR00117055 CYT-997 final compound C09 A549 48 262 Elongated +0.4207637359686342 7.838188869067759e-35 BR00117019 ixabepilone final compound J21 A549 48 430 Elongated 0.41220090146464183 2.250888488710826e-121 BR00117019 fludarabine final compound B06 A549 48 1588 Grape 0.30201455231282864 7.547208040371341e-118 BR00117019 LY2109761 final compound M02 A549 48 2916 Grape 0.37037233930664687 4.017773281425228e-99 BR00117015 fludarabine final compound B06 A549 48 1615 Grape @@ -209,6 +2009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.26786491166088056 6.607779388474042e-91 BR00117015 LY2109761 final compound M02 A549 48 2866 Grape 0.7863964924754118 1.986034613141544e-89 BR00117051 fludarabine-phosphate final compound N12 A549 48 290 Grape 0.30588721035192473 1.84749691189186e-86 BR00117017 dexamethasone final compound O02 A549 48 2079 Grape +0.6515620200956518 2.2561435556654644e-86 BR00117016 fludarabine-phosphate final compound N12 A549 48 428 Grape +0.25262077754689116 2.951729562526872e-83 BR00117016 LY2109761 final compound M02 A549 48 2954 Grape +0.42349457058242845 7.864350935634517e-82 BR00117055 fludarabine final compound B06 A549 48 1013 Grape +0.34293284895058923 1.461425302767358e-80 BR00117016 fludarabine final compound B06 A549 48 1533 Grape +0.3339083324510071 5.122339194303996e-79 BR00117015 dexamethasone final compound A21 A549 48 1587 Grape +0.33901394712397653 4.766734536450278e-78 BR00117015 JTE-607 final compound C14 A549 48 1524 Grape +0.7638055813691532 1.8799393841283677e-77 BR00117053 fludarabine-phosphate final compound N12 A549 48 267 Grape +0.32938240798502805 2.330259686099379e-77 BR00117017 dexamethasone final compound A21 A549 48 1603 Grape +0.6302036466966612 3.9563733502799644e-77 BR00117019 fludarabine-phosphate final compound N12 A549 48 412 Grape +0.2891080682736652 5.4855361586481074e-76 BR00117052 LY2109761 final compound M02 A549 48 2052 Grape +0.24470538953283955 1.0622201500764253e-75 BR00117017 LY2109761 final compound M02 A549 48 2862 Grape +0.7689338235294118 1.1572781596499647e-74 BR00117052 fludarabine-phosphate final compound N12 A549 48 255 Grape +0.2889478638944893 3.6300637245432604e-72 BR00117015 desonide final compound E16 A549 48 1945 Grape +0.28819981107678244 2.5116103117499844e-71 BR00117017 desonide final compound E16 A549 48 1938 Grape +0.2853989525237807 7.766707609686516e-71 BR00117019 PP-2 final compound J10 A549 48 1961 Grape +0.3066237451439001 3.9787051782387304e-70 BR00117016 JTE-607 final compound C14 A549 48 1678 Grape +0.261060008760403 9.004291935745985e-69 BR00117055 LY2109761 final compound M02 A549 48 2283 Grape +0.6930437148557954 1.2605975024319519e-68 BR00117050 fludarabine-phosphate final compound N12 A549 48 296 Grape +0.29711995373185784 2.6080262432343155e-68 BR00117017 JTE-607 final compound C14 A549 48 1739 Grape +0.2919651187287447 1.2173335549859858e-67 BR00117015 dexamethasone final compound O02 A549 48 1788 Grape +0.26938507716539756 3.379654703075886e-67 BR00117016 PP-2 final compound J10 A549 48 2093 Grape +0.4496636246088114 5.970516050537666e-67 BR00117051 fludarabine final compound B06 A549 48 730 Grape +0.4484181568088033 3.489941006910599e-66 BR00117053 fludarabine final compound B06 A549 48 727 Grape +0.3173734610123119 1.7779318157041078e-65 BR00117016 dexamethasone final compound A21 A549 48 1462 Grape +0.6441396078858315 2.917627250798287e-65 BR00117054 fludarabine-phosphate final compound N12 A549 48 331 Grape +0.37512741906037 6.767124039700404e-65 BR00117054 fludarabine final compound B06 A549 48 1027 Grape +0.2976113836493506 1.813787927118879e-64 BR00117019 JTE-607 final compound C14 A549 48 1638 Grape +0.3034810463784331 1.4853962174405797e-63 BR00117019 dexamethasone final compound A21 A549 48 1548 Grape +0.33558000835952523 3.2647908954880614e-63 BR00117015 ingenol-mebutate final compound M11 A549 48 1259 Grape +0.4774533413606261 4.002337071349488e-63 BR00117016 aminopurvalanol-a final compound K03 A549 48 605 Grape +0.5008294625082946 4.857888318095138e-63 BR00117016 geldanamycin final compound L01 A549 48 548 Grape +0.23026833436560915 5.941237167832916e-62 BR00117050 CC-401 final compound M09 A549 48 2642 Grape +0.2509849795692898 8.244096159099362e-62 BR00117054 LY2109761 final compound M02 A549 48 2220 Grape +0.38803473292413737 9.094212523448999e-62 BR00117055 dexamethasone final compound A21 A549 48 914 Grape +0.20013395043145177 1.3470129693872731e-61 BR00117015 CC-401 final compound M09 A549 48 3491 Grape +0.27901493061100563 2.2917749182086791e-60 BR00117051 LY2109761 final compound M02 A549 48 1746 Grape +0.3145590394748208 3.9090702319378975e-60 BR00117017 FK-866 final compound L09 A549 48 1362 Grape +0.2811084807232787 7.065695425201965e-58 BR00117054 PP-2 final compound J10 A549 48 1645 Grape +0.6134969325153374 1.368108628100154e-57 BR00117055 fludarabine-phosphate final compound N12 A549 48 326 Grape +0.4521151555400947 2.655925997096797e-57 BR00117019 aminopurvalanol-a final compound K03 A549 48 618 Grape +0.46410025169021474 4.445569047648795e-57 BR00117015 aminopurvalanol-a final compound K03 A549 48 582 Grape +0.24588475191360798 5.113154798571605e-57 BR00117017 PP-2 final compound J10 A549 48 2132 Grape +0.2523350696418209 7.589046526942927e-57 BR00117019 desonide final compound E16 A549 48 2011 Grape +0.4091745765004949 8.165688757766149e-57 BR00117050 fludarabine final compound B06 A549 48 751 Grape +0.22724930312798522 1.5040256857671387e-56 BR00117054 CC-401 final compound M09 A549 48 2474 Grape +0.41821324742673055 2.3638159911244227e-56 BR00117051 FK-866 final compound L09 A549 48 712 Grape +0.2655798695944681 1.2960165804410638e-55 BR00117019 dexamethasone final compound O02 A549 48 1776 Grape +0.40540540540540543 9.313097438499727e-55 BR00117052 fludarabine final compound B06 A549 48 740 Grape +0.30830268413873735 2.742182364264145e-54 BR00117016 ingenol-mebutate final compound M11 A549 48 1280 Grape +0.29528916321748916 4.7040714924503294e-54 BR00117052 PP-2 final compound J10 A549 48 1390 Grape +0.31629103010134624 1.0936298251477534e-53 BR00117055 JTE-607 final compound C14 A549 48 1202 Grape +0.27858615403886267 2.5336288648388996e-53 BR00117019 FK-866 final compound L09 A549 48 1543 Grape +0.34311395460656074 4.0869978890173456e-53 BR00117054 dexamethasone final compound A21 A549 48 1010 Grape +0.2870841755883307 7.8256015085470515e-53 BR00117016 FK-866 final compound D08 A549 48 1443 Grape +0.45412528647822764 8.404304864762746e-53 BR00117019 geldanamycin final compound L01 A549 48 560 Grape +0.34642298111556197 2.343460809360148e-52 BR00117054 FK-866 final compound L09 A549 48 974 Grape +0.30501167066346924 9.130334076976986e-52 BR00117015 FK-866 final compound D08 A549 48 1250 Grape +0.624497761451039 1.5754537610255848e-51 BR00117051 aminopurvalanol-a final compound K03 A549 48 279 Grape +0.24509206334910522 2.4294915688367762e-51 BR00117016 desonide final compound E16 A549 48 1932 Grape +0.3819039198349543 2.8274627729032016e-51 BR00117051 JTE-607 final compound C14 A549 48 780 Grape +0.17986013986013985 6.421207455961104e-51 BR00117019 CC-401 final compound M09 A549 48 3575 Grape +0.3417983272397696 6.048101114785315e-50 BR00117055 FK-866 final compound L09 A549 48 956 Grape +0.2617209236435756 1.9536228262891386e-49 BR00117050 LY2109761 final compound M02 A549 48 1625 Grape +0.4434848484848485 2.19342589200368e-49 BR00117017 aminopurvalanol-a final compound K03 A549 48 552 Grape +0.309725768321513 2.790353442341208e-48 BR00117019 ingenol-mebutate final compound M11 A549 48 1128 Grape +0.23518034712517974 3.594394905614986e-48 BR00117015 PP-2 final compound J10 A549 48 1962 Grape +0.27694734092781226 4.381094410561409e-48 BR00117017 FK-866 final compound D08 A549 48 1410 Grape +0.26819480856568806 2.705500841332601e-47 BR00117017 ingenol-mebutate final compound M11 A549 48 1477 Grape +0.26415263423654445 3.777036250145925e-47 BR00117055 dexamethasone final compound O02 A549 48 1524 Grape +0.29537088913592974 4.0408049268160967e-47 BR00117051 PP-2 final compound J10 A549 48 1213 Grape +0.4963855421686747 8.353430936951147e-47 BR00117054 aminopurvalanol-a final compound K03 A549 48 415 Grape +0.20360280630589334 1.7354299726516388e-46 BR00117017 RGFP966 final compound H03 A549 48 2532 Grape +0.36842421156014693 2.9559954988582596e-45 BR00117053 FK-866 final compound D08 A549 48 740 Grape +0.2774933193426291 3.627008844038033e-45 BR00117054 desonide final compound E16 A549 48 1319 Grape +0.34022988505747126 5.073371467840103e-45 BR00117015 thiostrepton final compound B02 A549 48 870 Grape +0.36044725045341 8.228484773702279e-45 BR00117052 FK-866 final compound D08 A549 48 765 Grape +0.2682604921882978 1.04172604274548e-44 BR00117055 desonide final compound E16 A549 48 1400 Grape +0.4379340277777778 1.402835544953527e-44 BR00117015 NVP-HSP990 final compound E23 A549 48 512 Grape +0.26286481224458325 2.395977881013902e-44 BR00117019 FK-866 final compound D08 A549 48 1441 Grape +0.33083247159945145 2.7113772186879113e-44 BR00117055 ingenol-mebutate final compound M11 A549 48 906 Grape +0.2578959008744154 3.5373733014590795e-44 BR00117017 NNC-55-0396 final compound A16 A549 48 1491 Grape +0.2253919737363446 4.039500130244329e-44 BR00117016 dexamethasone final compound O02 A549 48 1963 Grape +0.5405400287813376 4.768405333021186e-44 BR00117053 aminopurvalanol-a final compound K03 A549 48 324 Grape +0.4311309611693489 7.600498222414652e-44 BR00117017 geldanamycin final compound L01 A549 48 520 Grape +0.43521137828068523 1.155524725677432e-43 BR00117015 geldanamycin final compound L01 A549 48 505 Grape +0.3413173652694611 1.6621267154863904e-43 BR00117053 FK-866 final compound L09 A549 48 835 Grape +0.41407269157743826 3.976417081367658e-43 BR00117015 ganetespib final compound I17 A549 48 556 Grape +0.3559122595897093 8.7648807012695e-43 BR00117050 FK-866 final compound L09 A549 48 751 Grape +0.5792320923264718 2.3486075264805066e-42 BR00117052 geldanamycin final compound L01 A549 48 268 Grape +0.3605805958747135 6.01268847373285e-42 BR00117015 AZ191 final compound I18 A549 48 715 Grape 0.6506309185888415 8.970253174731074e-159 BR00117019 AMG900 final compound N09 A549 48 795 Hole 0.6553966189856957 2.3487916369546074e-156 BR00117017 AMG900 final compound N09 A549 48 769 Hole 0.6575293988350368 2.0116557346509536e-138 BR00117016 AMG900 final compound N09 A549 48 674 Hole @@ -219,6 +2109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.6909363980671281 1.5694958840869165e-113 BR00117050 AMG900 final compound N09 A549 48 496 Hole 0.7416976650383185 1.5781608436334312e-113 BR00117052 AMG900 final compound N09 A549 48 424 Hole 0.7176425870336439 1.5818662939012003e-113 BR00117053 AMG900 final compound N09 A549 48 452 Hole +0.5670043456176985 4.715738018954312e-112 BR00117017 PF-431396 final compound L20 A549 48 752 Hole +0.5984 2.3079194924104916e-104 BR00117016 PF-431396 final compound L20 A549 48 625 Hole +0.32386680021657666 9.418427679245997e-101 BR00117053 LY2109761 final compound M02 A549 48 2161 Hole +0.6764705882352942 1.7325174271344818e-96 BR00117051 AMG900 final compound N09 A549 48 442 Hole +0.6085772256038244 3.715595606930527e-93 BR00117054 AMG900 final compound N09 A549 48 537 Hole +0.2597615575619282 6.071473732557399e-87 BR00117019 LY2109761 final compound M02 A549 48 2916 Hole +0.6622501078671077 1.1203618556671449e-85 BR00117053 PF-431396 final compound L20 A549 48 409 Hole +0.5834949086343981 8.531039980118108e-85 BR00117016 epothilone-b final compound F07 A549 48 535 Hole +0.575992850929651 1.1274751419044502e-83 BR00117015 epothilone-b final compound F07 A549 48 544 Hole +0.5727611940298507 1.5030762523814195e-81 BR00117017 epothilone-b final compound F07 A549 48 536 Hole +0.2974825274568535 1.1475717019370137e-80 BR00117052 LY2109761 final compound M02 A549 48 2052 Hole +0.345116441739304 1.0385026055127206e-78 BR00117017 ingenol-mebutate final compound M11 A549 48 1477 Hole +0.5102685624012638 2.0123820530510362e-75 BR00117017 danusertib final compound N18 A549 48 633 Hole +0.5240303541315345 8.942609935825083e-75 BR00117015 danusertib final compound N18 A549 48 592 Hole +0.6610644257703081 3.910786718961773e-74 BR00117051 PF-431396 final compound L20 A549 48 357 Hole +0.5294392594278777 5.5362808786392524e-74 BR00117015 danusertib final compound E05 A549 48 575 Hole +0.5136335709353472 1.3478365846198408e-73 BR00117017 danusertib final compound E05 A549 48 607 Hole +0.6574130903482681 2.901736309962556e-73 BR00117052 PF-431396 final compound L20 A549 48 359 Hole +0.5685684600442698 8.431598197585166e-71 BR00117055 PF-431396 final compound L20 A549 48 471 Hole +0.5067796610169492 2.5368259776273123e-69 BR00117019 epothilone-b final compound F07 A549 48 590 Hole +0.2280237400738325 8.876298398126225e-66 BR00117015 LY2109761 final compound M02 A549 48 2866 Hole +0.4662114335678894 2.9164635127559487e-65 BR00117016 danusertib final compound E05 A549 48 657 Hole +0.35233017291087315 6.604264564831659e-65 BR00117019 polydatin final compound K08 A549 48 1170 Hole +0.22580674263382397 1.9202072941096043e-64 BR00117017 LY2109761 final compound M02 A549 48 2862 Hole +0.542526189487286 1.1908954381475586e-63 BR00117054 PF-431396 final compound L20 A549 48 465 Hole +0.2206739348890516 2.0975228366663553e-63 BR00117016 LY2109761 final compound M02 A549 48 2954 Hole +0.6533752447696589 2.2189710904424252e-63 BR00117052 oxibendazole final compound M19 A549 48 310 Hole +0.4611805144008534 4.6832060839857163e-63 BR00117019 danusertib final compound E05 A549 48 650 Hole +0.6199758031993547 2.155164372227369e-62 BR00117009 AMG900 final compound N09 A549 48 346 Hole +0.696023767283377 3.202823474996093e-62 BR00117053 fludarabine-phosphate final compound N12 A549 48 267 Hole +0.3389498435269442 3.8159478714541696e-62 BR00117015 polydatin final compound K08 A549 48 1211 Hole +0.6661926768574475 6.345091310085522e-62 BR00117051 fludarabine-phosphate final compound N12 A549 48 290 Hole +0.6828976034858388 4.569373994917238e-61 BR00117050 PF-431396 final compound L20 A549 48 270 Hole +0.48021851380677993 6.583068849190103e-61 BR00117052 polydatin final compound K08 A549 48 575 Hole +0.6518147740791452 8.819300191162862e-61 BR00117052 epothilone-b final compound F07 A549 48 298 Hole +0.2795590807017959 1.3004945153921056e-60 BR00117051 LY2109761 final compound M02 A549 48 1746 Hole +0.6556005964029448 2.2400395185376837e-60 BR00117053 danusertib final compound N18 A549 48 292 Hole +0.4925925925925926 7.886797841466828e-60 BR00117016 danusertib final compound N18 A549 48 540 Hole +0.32532317394252636 2.4538951988917114e-59 BR00117015 ingenol-mebutate final compound M11 A549 48 1259 Hole +0.3218555144193297 3.5165531777222404e-59 BR00117016 ingenol-mebutate final compound M11 A549 48 1280 Hole +0.6413907284768212 4.970819461219206e-59 BR00117051 epothilone-b final compound F07 A549 48 300 Hole +0.63590692755156 5.420051075609654e-59 BR00117052 briciclib final compound H01 A549 48 305 Hole +0.3411867612293144 1.4512889849952466e-58 BR00117019 ingenol-mebutate final compound M11 A549 48 1128 Hole +0.6289555562492846 6.24186213326335e-58 BR00117053 oxibendazole final compound M19 A549 48 309 Hole +0.32230784627702164 8.939978518551543e-58 BR00117016 polydatin final compound K08 A549 48 1248 Hole +0.33004965747218096 2.825009560019283e-57 BR00117017 polydatin final compound K08 A549 48 1175 Hole +0.593035265113025 5.183441863166197e-57 BR00117053 danusertib final compound E05 A549 48 347 Hole +0.45885628527390515 1.4832756170135861e-56 BR00117053 polydatin final compound K08 A549 48 588 Hole +0.6367240186247258 5.365057656588656e-56 BR00117053 CYT-997 final compound C09 A549 48 291 Hole +0.25345055805594113 8.72801357917412e-56 BR00117015 PP-2 final compound J10 A549 48 1962 Hole +0.2776846578835529 1.1263788389869395e-55 BR00117050 LY2109761 final compound M02 A549 48 1625 Hole +0.5124988159515014 1.7330216538619077e-55 BR00117015 fludarabine-phosphate final compound N12 A549 48 459 Hole +0.5020833333333333 2.2244237058018966e-55 BR00117015 oxibendazole final compound M19 A549 48 480 Hole +0.5794360699306507 1.5618942534911988e-54 BR00117052 danusertib final compound N18 A549 48 349 Hole +0.44413004214328716 4.399597493529385e-54 BR00117016 aminopurvalanol-a final compound K03 A549 48 605 Hole +0.24908902404841426 6.652129311198782e-54 BR00117019 PP-2 final compound J10 A549 48 1961 Hole +0.6085776330076005 1.1381101747145937e-53 BR00117008 AMG900 final compound N09 A549 48 307 Hole +0.5936340225706279 1.415139071805273e-53 BR00117053 aminopurvalanol-a final compound K03 A549 48 324 Hole +0.4469111969111969 1.524429824108846e-53 BR00117051 polydatin final compound K08 A549 48 588 Hole +0.6295476036430597 4.548387414046502e-53 BR00117050 epothilone-b final compound F07 A549 48 283 Hole +0.21286387722799532 6.114342259514706e-53 BR00117050 CC-401 final compound M09 A549 48 2642 Hole +0.6095592236531834 4.001522484025387e-52 BR00117050 fludarabine-phosphate final compound N12 A549 48 296 Hole +0.18377459588325892 5.697605046905596e-52 BR00117015 CC-401 final compound M09 A549 48 3491 Hole +0.5116226120519548 6.060130049828688e-52 BR00117016 ixabepilone final compound J21 A549 48 431 Hole +0.5734245794126034 1.0899270704996292e-51 BR00117008 PF-431396 final compound L20 A549 48 336 Hole +0.5142208969974674 2.108309236947052e-51 BR00117015 ixabepilone final compound J21 A549 48 423 Hole +0.3524945770065076 3.1010204967812645e-51 BR00117054 ingenol-mebutate final compound M11 A549 48 922 Hole +0.6552337063857802 1.5005677334700012e-50 BR00117053 briciclib final compound H01 A549 48 245 Hole +0.42409053055458923 2.443762969721063e-50 BR00117019 aminopurvalanol-a final compound K03 A549 48 618 Hole +0.6145614102220691 3.604561681048744e-50 BR00117051 aminopurvalanol-a final compound K03 A549 48 279 Hole +0.579815251572327 4.66967141041913e-50 BR00117052 danusertib final compound E05 A549 48 318 Hole +0.6312371484785277 1.856279489980364e-49 BR00117053 colchicine final compound K17 A549 48 261 Hole +0.5872544909214048 1.876089002704449e-49 BR00117051 danusertib final compound E05 A549 48 303 Hole +0.6361519607843137 2.1851807258816064e-49 BR00117052 fludarabine-phosphate final compound N12 A549 48 255 Hole +0.4620121449315877 2.580541719911859e-49 BR00117017 fludarabine-phosphate final compound N12 A549 48 507 Hole +0.21214592194837614 3.1175995432512737e-49 BR00117054 CC-401 final compound M09 A549 48 2474 Hole +0.6116092801780469 3.910428754083628e-49 BR00117052 ixabepilone final compound J21 A549 48 279 Hole +0.6435549436139523 1.4376070921473607e-48 BR00117053 epothilone-b final compound F07 A549 48 246 Hole +0.6090318345914014 1.5218345175845117e-48 BR00117052 colchicine final compound K17 A549 48 277 Hole +0.6258576138287445 5.0404540941905904e-48 BR00117050 oxibendazole final compound M19 A549 48 258 Hole +0.6137112444031427 1.0061176052924567e-47 BR00117053 CYT-997 final compound E06 A549 48 267 Hole +0.5784313725490197 1.0922958636725727e-47 BR00117009 PF-431396 final compound L20 A549 48 306 Hole +0.5617283950617284 1.9557474690970255e-47 BR00117050 danusertib final compound E05 A549 48 324 Hole +0.4803021639028501 4.826219961299279e-47 BR00117017 ixabepilone final compound J21 A549 48 446 Hole +0.5748995765932038 7.359966839664211e-47 BR00117050 danusertib final compound N18 A549 48 305 Hole +0.6217169260700389 9.201606210581621e-47 BR00117050 colchicine final compound K17 A549 48 256 Hole +0.5792868871686606 4.705591490445652e-46 BR00117009 epothilone-b final compound F07 A549 48 290 Hole +0.281304230671889 5.003966660870543e-46 BR00117015 NNC-55-0396 final compound A16 A549 48 1307 Hole +0.6216608594657376 1.7022744743428963e-45 BR00117051 oxibendazole final compound M19 A549 48 246 Hole +0.5008000524624565 2.6032580427005122e-45 BR00117054 epothilone-b final compound F07 A549 48 391 Hole 0.3414906859744775 2.046894583420891e-151 BR00117019 LY2109761 final compound M02 A549 48 2916 Interphase 0.38398115303981434 1.5597077478725993e-142 BR00117053 LY2109761 final compound M02 A549 48 2161 Interphase 0.31428346185402656 9.970322511497426e-126 BR00117015 LY2109761 final compound M02 A549 48 2866 Interphase @@ -229,6 +2209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5458022247135622 7.341867012872493e-109 BR00117019 AMG900 final compound N09 A549 48 795 Interphase 0.34049211795057105 2.024098513308105e-101 BR00117019 PP-2 final compound J10 A549 48 1961 Interphase 0.664671942614323 9.71247555541966e-96 BR00117053 AMG900 final compound N09 A549 48 452 Interphase +0.5101726959760708 4.9979530100436215e-90 BR00117017 PF-431396 final compound L20 A549 48 752 Interphase +0.3080032096050403 4.4753670755448495e-88 BR00117016 PP-2 final compound J10 A549 48 2093 Interphase +0.6141031082669453 1.3553343876733478e-87 BR00117050 AMG900 final compound N09 A549 48 496 Interphase +0.33457738662061104 4.090864907267675e-87 BR00117051 LY2109761 final compound M02 A549 48 1746 Interphase +0.6447963800904978 7.570815764803812e-87 BR00117051 AMG900 final compound N09 A549 48 442 Interphase +0.5062586926286509 3.219261815743466e-84 BR00117019 PF-431396 final compound L20 A549 48 719 Interphase +0.396869503018094 5.1357028704170415e-83 BR00117019 polydatin final compound K08 A549 48 1170 Interphase +0.5153027805253324 1.7954631819278753e-82 BR00117016 AMG900 final compound N09 A549 48 674 Interphase +0.3887121556112116 2.2870536002416872e-82 BR00117015 polydatin final compound K08 A549 48 1211 Interphase +0.6401145072379331 7.901940485782498e-82 BR00117052 AMG900 final compound N09 A549 48 424 Interphase +0.5446653915366072 1.2326026123838845e-81 BR00117055 AMG900 final compound N09 A549 48 593 Interphase +0.5023229085729086 1.9607517363435928e-81 BR00117015 AMG900 final compound N09 A549 48 702 Interphase +0.3014397858859855 2.5662306497220992e-79 BR00117015 PP-2 final compound J10 A549 48 1962 Interphase +0.3860814092573127 1.8618102947858198e-78 BR00117017 polydatin final compound K08 A549 48 1175 Interphase +0.2867117652758326 1.2041505824969388e-77 BR00117017 PP-2 final compound J10 A549 48 2132 Interphase +0.3255773716768192 9.111072462915263e-77 BR00117050 LY2109761 final compound M02 A549 48 1625 Interphase +0.2728865527814279 3.4622201175909853e-75 BR00117055 LY2109761 final compound M02 A549 48 2283 Interphase +0.3421095548238597 7.766339069878198e-73 BR00117052 PP-2 final compound J10 A549 48 1390 Interphase +0.21758727997386926 7.912807337798199e-73 BR00117015 CC-401 final compound M09 A549 48 3491 Interphase +0.35525279197717147 1.3135714220734978e-70 BR00117016 polydatin final compound K08 A549 48 1248 Interphase +0.26811184493781426 1.406910092878174e-70 BR00117054 LY2109761 final compound M02 A549 48 2220 Interphase +0.46814296814296813 2.3738789528109972e-70 BR00117015 PF-431396 final compound L20 A549 48 702 Interphase +0.5261194029850746 3.767365137114855e-68 BR00117017 epothilone-b final compound F07 A549 48 536 Interphase +0.5017236624379482 4.320674846791579e-68 BR00117051 polydatin final compound K08 A549 48 588 Interphase +0.5936286495038113 2.4457012998999727e-67 BR00117053 PF-431396 final compound L20 A549 48 409 Interphase +0.28160915991280655 1.899306510864662e-66 BR00117019 PP-1 final compound A22 A549 48 1889 Interphase +0.517103727174185 8.013308912812945e-66 BR00117054 AMG900 final compound N09 A549 48 537 Interphase +0.6246498599439776 1.5600163230866177e-65 BR00117051 PF-431396 final compound L20 A549 48 357 Interphase +0.20307692307692307 6.806812642997327e-65 BR00117019 CC-401 final compound M09 A549 48 3575 Interphase +0.265054641571601 2.7612284728802757e-64 BR00117016 PP-1 final compound A22 A549 48 2061 Interphase +0.4704 7.166483886899774e-63 BR00117016 PF-431396 final compound L20 A549 48 625 Interphase +0.4808202667779207 5.963804895758414e-62 BR00117053 polydatin final compound K08 A549 48 588 Interphase +0.6042128952048219 4.68289238847246e-61 BR00117052 PF-431396 final compound L20 A549 48 359 Interphase +0.22840679696281513 6.125398695339937e-61 BR00117050 CC-401 final compound M09 A549 48 2642 Interphase +0.3315792375878438 2.0174332971046208e-59 BR00117051 PP-2 final compound J10 A549 48 1213 Interphase +0.23168477397065126 9.107254931963145e-59 BR00117054 CC-401 final compound M09 A549 48 2474 Interphase +0.4709511337274564 1.3491622557039766e-58 BR00117052 polydatin final compound K08 A549 48 575 Interphase +0.6315673289183223 3.480160991488232e-57 BR00117051 epothilone-b final compound F07 A549 48 300 Interphase +0.6196838676781236 1.6495454536180452e-56 BR00117053 oxibendazole final compound M19 A549 48 309 Interphase +0.24169978886299354 1.7528984665538013e-56 BR00117017 PP-1 final compound A22 A549 48 2187 Interphase +0.4559322033898305 1.1714703984779638e-55 BR00117019 epothilone-b final compound F07 A549 48 590 Interphase +0.6149129135318974 1.233080603757496e-55 BR00117052 oxibendazole final compound M19 A549 48 310 Interphase +0.3428844317096466 5.865778171033599e-55 BR00117050 PP-2 final compound J10 A549 48 1047 Interphase +0.1860236249876375 2.3917431156886838e-54 BR00117016 CC-401 final compound M09 A549 48 3567 Interphase +0.33594963355822155 1.0029816760268427e-53 BR00117008 LY2109761 final compound M02 A549 48 1061 Interphase +0.3783132530120482 2.738867262110578e-53 BR00117008 PP-2 final compound J10 A549 48 830 Interphase +0.2695428172561649 3.6469554177053483e-53 BR00117054 PP-2 final compound J10 A549 48 1645 Interphase +0.2688708671241422 2.3184784836687588e-51 BR00117017 dexamethasone final compound A21 A549 48 1603 Interphase +0.4557022670436012 2.84525229497974e-51 BR00117015 epothilone-b final compound F07 A549 48 544 Interphase +0.48762253241179926 4.0062528684007517e-51 BR00117055 PF-431396 final compound L20 A549 48 471 Interphase +0.6014230881461695 6.018390224662334e-51 BR00117052 epothilone-b final compound F07 A549 48 298 Interphase +0.4549204910029293 1.0635710048597384e-50 BR00117016 epothilone-b final compound F07 A549 48 535 Interphase +0.32378311768330253 1.0826771007887486e-50 BR00117009 LY2109761 final compound M02 A549 48 1082 Interphase +0.23822704924656016 1.7231488334586942e-49 BR00117015 PP-1 final compound A22 A549 48 1964 Interphase +0.44180087608776547 2.7898075925525643e-49 BR00117050 polydatin final compound K08 A549 48 553 Interphase +0.27492945407032787 6.842958002838697e-49 BR00117055 PP-2 final compound J10 A549 48 1457 Interphase +0.2299519438261637 9.963400044094199e-49 BR00117017 dexamethasone final compound O02 A549 48 2079 Interphase +0.17589553597019084 1.8412796035649682e-47 BR00117017 CC-401 final compound M09 A549 48 3481 Interphase +0.6060185185185185 3.7486979071956816e-47 BR00117050 PF-431396 final compound L20 A549 48 270 Interphase +0.29494614747307374 1.0819296477420306e-46 BR00117053 PP-2 final compound J10 A549 48 1207 Interphase +0.5355726576152708 8.82228106974902e-46 BR00117009 AMG900 final compound N09 A549 48 346 Interphase +0.3153051702992214 3.282318009056468e-45 BR00117052 PP-1 final compound A22 A549 48 1019 Interphase +0.6154665118079752 9.523598300375702e-45 BR00117051 oxibendazole final compound M19 A549 48 246 Interphase +0.5720183432438455 9.678415170247914e-45 BR00117053 CYT-997 final compound C09 A549 48 291 Interphase +0.5561078794288736 2.363055280893309e-44 BR00117052 briciclib final compound H01 A549 48 305 Interphase +0.6078431372549019 3.1269625815695903e-44 BR00117051 ixabepilone final compound J21 A549 48 255 Interphase +0.5875912408759124 3.4631790110528527e-44 BR00117051 colchicine final compound K17 A549 48 274 Interphase +0.30242189985863993 9.834405115907706e-44 BR00117051 PP-1 final compound A22 A549 48 1074 Interphase +0.31144550530375137 1.1335601749663237e-43 BR00117054 dexamethasone final compound A21 A549 48 1010 Interphase +0.5966764679675666 1.1943405664615e-43 BR00117050 oxibendazole final compound M19 A549 48 258 Interphase +0.5986290126459144 1.4492784774115308e-43 BR00117050 ixabepilone final compound J21 A549 48 256 Interphase +0.5629696909371423 3.0677167990861077e-42 BR00117050 epothilone-b final compound F07 A549 48 283 Interphase +0.43232323232323233 6.462724020861604e-42 BR00117017 CYT-997 final compound C09 A549 48 495 Interphase +0.3542234332425068 2.8245252150624444e-41 BR00117055 polydatin final compound K08 A549 48 734 Interphase +0.24133625036333997 3.8451081540725777e-41 BR00117015 dexamethasone final compound A21 A549 48 1587 Interphase +0.4329845325695948 5.30879639218656e-41 BR00117017 briciclib final compound H01 A549 48 482 Interphase +0.3642438256679884 2.0265015800714638e-40 BR00117008 PP-1 final compound A22 A549 48 673 Interphase +0.44462334848165647 2.379439605639228e-40 BR00117017 ixabepilone final compound J21 A549 48 446 Interphase +0.5100156829198745 4.071897303591545e-40 BR00117008 PF-431396 final compound L20 A549 48 336 Interphase +0.5648109036636535 7.467817943927897e-40 BR00117053 CYT-997 final compound E06 A549 48 267 Interphase +0.551086314407614 2.764469515795586e-39 BR00117052 colchicine final compound K17 A549 48 277 Interphase +0.5690172931552242 2.8099009042776008e-39 BR00117053 colchicine final compound K17 A549 48 261 Interphase +0.570829280155642 5.710772847472996e-39 BR00117050 colchicine final compound K17 A549 48 256 Interphase +0.577668016194332 5.725130759524329e-39 BR00117053 ixabepilone final compound J21 A549 48 247 Interphase +0.5235996678801814 7.740246766044437e-39 BR00117008 AMG900 final compound N09 A549 48 307 Interphase +0.23700018647273502 1.0171101486538638e-38 BR00117019 dexamethasone final compound A21 A549 48 1548 Interphase +0.5780776826859776 1.2648392788590256e-38 BR00117053 briciclib final compound H01 A549 48 245 Interphase +0.20421946558235163 1.2966653283575966e-38 BR00117052 CC-401 final compound M09 A549 48 2088 Interphase +0.44357286900709064 1.4404785410551376e-38 BR00117016 ixabepilone final compound J21 A549 48 431 Interphase +0.44183898168537517 1.4590447228734702e-38 BR00117019 ixabepilone final compound J21 A549 48 430 Interphase 0.4503754754396801 2.1851223408225286e-148 BR00117015 fludarabine final compound B06 A549 48 1615 Large 0.4394760014238536 1.4928969922070679e-133 BR00117016 fludarabine final compound B06 A549 48 1533 Large 0.4291200396415741 1.0190917818895116e-131 BR00117019 fludarabine final compound B06 A549 48 1588 Large @@ -239,6 +2309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.7105380316377758 4.9729670959654845e-112 BR00117015 fludarabine-phosphate final compound N12 A549 48 459 Large 0.41120040773780386 5.987620509335314e-110 BR00117016 FK-866 final compound D08 A549 48 1443 Large 0.41944156517232445 1.0326485595046629e-107 BR00117017 FK-866 final compound L09 A549 48 1362 Large +0.5686350686350686 2.3325158961689963e-105 BR00117015 PF-431396 final compound L20 A549 48 702 Large +0.5671822390572391 8.463042873285076e-105 BR00117015 AMG900 final compound N09 A549 48 702 Large +0.5342540689677107 3.910268306889944e-104 BR00117019 AMG900 final compound N09 A549 48 795 Large +0.5549374130737135 3.5574035658289616e-102 BR00117019 PF-431396 final compound L20 A549 48 719 Large +0.4250570743405276 4.849669808111945e-102 BR00117015 FK-866 final compound D08 A549 48 1250 Large +0.4698914116485686 1.9209878951199495e-101 BR00117055 fludarabine final compound B06 A549 48 1013 Large +0.6471563465809378 1.6273139378751089e-100 BR00117017 fludarabine-phosphate final compound N12 A549 48 507 Large +0.5253576072821846 2.5256425844331947e-97 BR00117017 AMG900 final compound N09 A549 48 769 Large +0.3913025134108854 4.3829802902124894e-97 BR00117017 FK-866 final compound D08 A549 48 1410 Large +0.40359604383486114 8.650675803006505e-97 BR00117015 FK-866 final compound L09 A549 48 1319 Large +0.5389467274298735 1.3024267259295114e-95 BR00117051 FK-866 final compound L09 A549 48 712 Large +0.5254987583949433 1.6399798573581485e-95 BR00117017 PF-431396 final compound L20 A549 48 752 Large +0.3610006377918197 3.59232888621833e-95 BR00117019 JTE-607 final compound C14 A549 48 1638 Large +0.4193795717174184 4.4436332796582465e-95 BR00117055 JTE-607 final compound C14 A549 48 1202 Large +0.5943941118446012 5.4742470217717355e-95 BR00117015 danusertib final compound E05 A549 48 575 Large +0.5505308275634685 2.3390333494151934e-94 BR00117016 AMG900 final compound N09 A549 48 674 Large +0.5639810426540285 3.903514632403541e-93 BR00117017 danusertib final compound N18 A549 48 633 Large +0.5202702702702703 9.012122548275855e-92 BR00117052 fludarabine final compound B06 A549 48 740 Large +0.5144744618583422 3.5354920443667425e-91 BR00117050 FK-866 final compound L09 A549 48 751 Large +0.5459926514163802 1.1163168876926106e-89 BR00117019 danusertib final compound E05 A549 48 650 Large +0.5167625508311002 1.8401073877099537e-89 BR00117051 fludarabine final compound B06 A549 48 730 Large +0.5616578184007444 1.4152315527604812e-88 BR00117016 aminopurvalanol-a final compound K03 A549 48 605 Large +0.7830430145751867 1.570063643618873e-88 BR00117051 fludarabine-phosphate final compound N12 A549 48 290 Large +0.4360917341163583 4.1681714068203125e-88 BR00117054 fludarabine final compound B06 A549 48 1027 Large +0.538963141848598 6.149780964983207e-88 BR00117016 danusertib final compound E05 A549 48 657 Large +0.7511060849552605 7.697221297618869e-88 BR00117019 AR-12 final compound C10 A549 48 318 Large +0.49900934195667795 5.457975890603303e-87 BR00117052 FK-866 final compound D08 A549 48 765 Large +0.49322625012280186 9.30015684029722e-87 BR00117051 JTE-607 final compound C14 A549 48 780 Large +0.6512877890395331 2.307092347268567e-86 BR00117016 fludarabine-phosphate final compound N12 A549 48 428 Large +0.587030966662017 5.992855775495247e-86 BR00117016 epothilone-b final compound F07 A549 48 535 Large +0.38233054074638234 6.629979373981625e-86 BR00117016 FK-866 final compound L09 A549 48 1313 Large +0.5559910669522811 1.2214567504847015e-84 BR00117015 danusertib final compound N18 A549 48 592 Large +0.4983121748936015 3.4126612067737483e-84 BR00117053 FK-866 final compound D08 A549 48 740 Large +0.4956136915485235 4.475312000611917e-84 BR00117050 fludarabine final compound B06 A549 48 751 Large +0.5392 1.2768640669019215e-83 BR00117016 PF-431396 final compound L20 A549 48 625 Large +0.545136226967013 1.6189542258585892e-83 BR00117017 danusertib final compound E05 A549 48 607 Large +0.5140772547171458 3.372229977591418e-82 BR00117051 FK-866 final compound D08 A549 48 676 Large +0.5746268656716418 4.078251917006458e-82 BR00117017 epothilone-b final compound F07 A549 48 536 Large +0.4965612104539202 8.855127381448064e-82 BR00117053 fludarabine final compound B06 A549 48 727 Large +0.46467065868263474 9.124726836998979e-82 BR00117053 FK-866 final compound L09 A549 48 835 Large +0.3564581887578071 1.0336120955582685e-81 BR00117019 FK-866 final compound D08 A549 48 1441 Large +0.3404829701959053 6.173621247265622e-80 BR00117019 FK-866 final compound L09 A549 48 1543 Large +0.413882506127451 6.822697136870703e-79 BR00117055 FK-866 final compound D08 A549 48 1024 Large +0.4273084047182222 1.344231160682801e-78 BR00117055 FK-866 final compound L09 A549 48 956 Large +0.7581227436823105 2.795959539349938e-78 BR00117017 AR-12 final compound C10 A549 48 277 Large +0.7809283088235294 4.598788446335378e-78 BR00117052 fludarabine-phosphate final compound N12 A549 48 255 Large +0.5574074074074075 1.5013992814039442e-77 BR00117016 danusertib final compound N18 A549 48 540 Large +0.46703878748370276 5.207793187976711e-76 BR00117052 FK-866 final compound L09 A549 48 768 Large +0.5295986513648447 3.4643466255452227e-75 BR00117015 aminopurvalanol-a final compound K03 A549 48 582 Large +0.4124006968054667 6.386976401987533e-75 BR00117054 FK-866 final compound L09 A549 48 974 Large +0.5435162281178645 3.3751115992738426e-74 BR00117015 epothilone-b final compound F07 A549 48 544 Large +0.4323699421965318 5.5905578469892655e-73 BR00117053 JTE-607 final compound C14 A549 48 865 Large +0.41422939805292747 1.8732382275605324e-72 BR00117054 FK-866 final compound D08 A549 48 935 Large +0.6809815950920245 2.696562886155135e-72 BR00117055 fludarabine-phosphate final compound N12 A549 48 326 Large +0.5380333951762524 7.807872770936353e-72 BR00117009 fludarabine final compound B06 A549 48 539 Large +0.7035416288771994 6.4623961819170886e-71 BR00117050 fludarabine-phosphate final compound N12 A549 48 296 Large +0.6057778830215487 1.0801779397690246e-70 BR00117019 fludarabine-phosphate final compound N12 A549 48 412 Large +0.5081572484353248 1.9392786906540828e-70 BR00117055 AMG900 final compound N09 A549 48 593 Large +0.49892476518769174 2.3733902176930014e-70 BR00117019 aminopurvalanol-a final compound K03 A549 48 618 Large +0.7336318323899637 2.8845954541321692e-70 BR00117053 fludarabine-phosphate final compound N12 A549 48 267 Large +0.528786446847982 3.969256213817244e-69 BR00117019 danusertib final compound N18 A549 48 535 Large +0.6882906866735605 6.248452903328002e-69 BR00117015 AR-12 final compound C10 A549 48 301 Large +0.3200858051996742 1.401668484781737e-67 BR00117017 ingenol-mebutate final compound M11 A549 48 1477 Large +0.45355878731917515 2.0727440951349675e-67 BR00117050 FK-866 final compound D08 A549 48 722 Large +0.4966101694915254 1.8875145231520618e-66 BR00117019 epothilone-b final compound F07 A549 48 590 Large +0.5175866477667528 2.54885156226313e-66 BR00117054 AMG900 final compound N09 A549 48 537 Large +0.5497854271129783 4.0669983357911775e-66 BR00117055 PF-431396 final compound L20 A549 48 471 Large +0.5100530856005309 1.2112060139971997e-65 BR00117016 geldanamycin final compound L01 A549 48 548 Large +0.3808164610527001 9.208435784076073e-65 BR00117054 JTE-607 final compound C14 A549 48 991 Large +0.6388412581766056 1.4387339572902396e-64 BR00117054 fludarabine-phosphate final compound N12 A549 48 331 Large +0.6887077641296445 8.003741797882204e-64 BR00117051 aminopurvalanol-a final compound K03 A549 48 279 Large +0.39221621751742236 4.1803492606499054e-63 BR00117052 JTE-607 final compound C14 A549 48 910 Large +0.28830409356725145 5.093265823473291e-63 BR00117019 AC-710 final compound I03 A549 48 1710 Large +0.4588671422701976 1.3325874541537373e-62 BR00117009 FK-866 final compound D08 A549 48 656 Large +0.4923583662714098 2.5932809597944335e-61 BR00117017 aminopurvalanol-a final compound K03 A549 48 552 Large +0.4038872500322294 1.0025464880422884e-59 BR00117050 JTE-607 final compound C14 A549 48 815 Large +0.7647058823529411 7.112417556771257e-59 BR00117054 AR-12 final compound C10 A549 48 204 Large +0.5725806451612904 1.1556448310374878e-56 BR00117054 danusertib final compound E05 A549 48 372 Large +0.49782062165338903 2.2880619611581492e-56 BR00117050 AMG900 final compound N09 A549 48 496 Large +0.6674124769676231 5.0214906674571055e-56 BR00117016 AR-12 final compound C10 A549 48 262 Large +0.3727652730277402 1.6801726746247436e-55 BR00117050 purvalanol-a final compound G17 A549 48 889 Large +0.5373493975903615 3.0580013177016785e-55 BR00117054 aminopurvalanol-a final compound K03 A549 48 415 Large +0.5352370108467669 2.4399923335006085e-54 BR00117055 danusertib final compound E05 A549 48 410 Large +0.5012552494346763 1.302016543581806e-53 BR00117054 PF-431396 final compound L20 A549 48 465 Large +0.5370201699780774 1.9955090996139751e-53 BR00117055 aminopurvalanol-a final compound K03 A549 48 401 Large +0.5903582519124442 5.90256036813232e-53 BR00117053 aminopurvalanol-a final compound K03 A549 48 324 Large +0.5230955462869744 8.233798415696583e-52 BR00117053 PF-431396 final compound L20 A549 48 409 Large +0.5948764257533246 8.712629085649336e-51 BR00117051 danusertib final compound E05 A549 48 303 Large +0.497737556561086 4.1469578271849987e-50 BR00117051 AMG900 final compound N09 A549 48 442 Large +0.5479989928080198 1.2165545770965803e-49 BR00117052 PF-431396 final compound L20 A549 48 359 Large 0.5973840973840974 5.472598979282511e-117 BR00117015 AMG900 final compound N09 A549 48 702 Metaphase 0.5901118557368558 5.634317102162392e-114 BR00117015 PF-431396 final compound L20 A549 48 702 Metaphase 0.5425120657713745 8.555203727928548e-108 BR00117019 AMG900 final compound N09 A549 48 795 Metaphase @@ -249,6 +2409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.6158039416670549 1.2490252740630383e-90 BR00117017 fludarabine-phosphate final compound N12 A549 48 507 Metaphase 0.8163667595956182 1.4303692727539019e-90 BR00117053 fludarabine-phosphate final compound N12 A549 48 267 Metaphase 0.5651113786875376 7.852140898743137e-90 BR00117016 aminopurvalanol-a final compound K03 A549 48 605 Metaphase +0.5688824880880972 2.7877920438825007e-89 BR00117055 AMG900 final compound N09 A549 48 593 Metaphase +0.5912186038925736 9.160467114842169e-89 BR00117015 epothilone-b final compound F07 A549 48 544 Metaphase +0.5945738596735947 2.633742563768964e-88 BR00117016 epothilone-b final compound F07 A549 48 535 Metaphase +0.5118219749652295 3.620652901281508e-86 BR00117019 PF-431396 final compound L20 A549 48 719 Metaphase +0.5493817399829227 4.736500662309495e-86 BR00117019 aminopurvalanol-a final compound K03 A549 48 618 Metaphase +0.764261744966443 1.2107762985777859e-85 BR00117050 fludarabine-phosphate final compound N12 A549 48 296 Metaphase +0.5839552238805971 5.515180162638183e-85 BR00117017 epothilone-b final compound F07 A549 48 536 Metaphase +0.5576271186440678 9.059307349758765e-85 BR00117019 epothilone-b final compound F07 A549 48 590 Metaphase +0.558778801435872 3.5983223354517146e-84 BR00117015 aminopurvalanol-a final compound K03 A549 48 582 Metaphase +0.637356851388706 2.2634827516176443e-82 BR00117016 fludarabine-phosphate final compound N12 A549 48 428 Metaphase +0.6138052059283533 5.0823747421301494e-82 BR00117015 CYT-997 final compound C09 A549 48 464 Metaphase +0.4885715898188385 6.321897311633483e-82 BR00117017 PF-431396 final compound L20 A549 48 752 Metaphase +0.5821307300509337 1.7835298440705163e-78 BR00117050 AMG900 final compound N09 A549 48 496 Metaphase +0.7767922794117647 1.885057020254224e-76 BR00117052 fludarabine-phosphate final compound N12 A549 48 255 Metaphase +0.3425501465667671 1.6527763451326688e-75 BR00117016 FK-866 final compound D08 A549 48 1443 Metaphase +0.32262142614374517 1.462812071979639e-73 BR00117019 fludarabine final compound B06 A549 48 1588 Metaphase +0.5340711462450592 1.14660757863132e-72 BR00117017 aminopurvalanol-a final compound K03 A549 48 552 Metaphase +0.6082879469571395 1.9711809287944772e-71 BR00117019 fludarabine-phosphate final compound N12 A549 48 412 Metaphase +0.5422024489735539 1.612606074805622e-70 BR00117019 CYT-997 final compound C09 A549 48 519 Metaphase +0.3395417638421007 3.5019540850054105e-70 BR00117017 FK-866 final compound L09 A549 48 1362 Metaphase +0.31089289914463886 1.696109946190621e-69 BR00117015 fludarabine final compound B06 A549 48 1615 Metaphase +0.3421749718565488 5.396769200227155e-69 BR00117015 FK-866 final compound L09 A549 48 1319 Metaphase +0.5107155322862129 5.757236154730939e-69 BR00117015 danusertib final compound E05 A549 48 575 Metaphase +0.5601526855490807 7.983598081276998e-69 BR00117055 PF-431396 final compound L20 A549 48 471 Metaphase +0.564236240411112 9.807064318888782e-69 BR00117015 colchicine final compound K17 A549 48 464 Metaphase +0.34751910471622705 1.1526873683504658e-67 BR00117015 FK-866 final compound D08 A549 48 1250 Metaphase +0.566683560095123 1.366489339234822e-67 BR00117053 AMG900 final compound N09 A549 48 452 Metaphase +0.5520833333333334 1.3829406892454102e-67 BR00117015 oxibendazole final compound M19 A549 48 480 Metaphase +0.5699280705450387 2.4803287683624334e-67 BR00117017 colchicine final compound K17 A549 48 446 Metaphase +0.5629139072847682 1.75963164835164e-66 BR00117015 CYT-997 final compound E06 A549 48 453 Metaphase +0.48 1.4611317340018988e-65 BR00117016 PF-431396 final compound L20 A549 48 625 Metaphase +0.5438300078666952 6.299904736604901e-65 BR00117016 CYT-997 final compound C09 A549 48 474 Metaphase +0.5340652893600972 1.9193565603351158e-64 BR00117017 oxibendazole final compound M19 A549 48 490 Metaphase +0.38733946649419904 2.923039037654107e-64 BR00117055 FK-866 final compound L09 A549 48 956 Metaphase +0.5588235294117647 7.01041908665233e-64 BR00117051 AMG900 final compound N09 A549 48 442 Metaphase +0.6888353167769997 7.993658155344142e-64 BR00117051 aminopurvalanol-a final compound K03 A549 48 279 Metaphase +0.37950440973507926 4.1537448550629e-63 BR00117054 FK-866 final compound L09 A549 48 974 Metaphase +0.2849950800395185 1.2809815868006455e-62 BR00117017 JTE-607 final compound C14 A549 48 1739 Metaphase +0.3016027089832892 1.6687080476632333e-62 BR00117019 FK-866 final compound L09 A549 48 1543 Metaphase +0.502577892659607 2.126849845390829e-62 BR00117054 AMG900 final compound N09 A549 48 537 Metaphase +0.5547945205479452 2.4111716822315626e-62 BR00117015 briciclib final compound H01 A549 48 438 Metaphase +0.314611335463002 3.8792025422423186e-62 BR00117017 FK-866 final compound D08 A549 48 1410 Metaphase +0.310656180121829 6.605693736125041e-62 BR00117019 FK-866 final compound D08 A549 48 1441 Metaphase +0.560530856451396 7.647858604394103e-62 BR00117052 AMG900 final compound N09 A549 48 424 Metaphase +0.5458612975391499 1.7851758238751214e-61 BR00117019 briciclib final compound H01 A549 48 447 Metaphase +0.4279600596558874 2.2264754044689537e-61 BR00117053 FK-866 final compound D08 A549 48 740 Metaphase +0.30112050545653307 6.053288676655458e-61 BR00117017 fludarabine final compound B06 A549 48 1509 Metaphase +0.5697361534435517 6.254063788428497e-61 BR00117016 CYT-997 final compound E06 A549 48 401 Metaphase +0.5171717171717172 9.660927254829794e-61 BR00117017 CYT-997 final compound C09 A549 48 495 Metaphase +0.5408101844885184 2.8486353480470496e-60 BR00117016 oxibendazole final compound M19 A549 48 446 Metaphase +0.4715714871701381 5.698174396296472e-60 BR00117015 danusertib final compound N18 A549 48 592 Metaphase +0.29530698863471855 1.461905720067063e-59 BR00117016 fludarabine final compound B06 A549 48 1533 Metaphase +0.5502321951000376 1.8003932485715326e-59 BR00117015 ixabepilone final compound J21 A549 48 423 Metaphase +0.2956547289763435 3.9053486238041246e-59 BR00117015 JTE-607 final compound C14 A549 48 1524 Metaphase +0.6212224494433083 4.723197623599441e-59 BR00117053 aminopurvalanol-a final compound K03 A549 48 324 Metaphase +0.445850420765675 7.4504042957373415e-59 BR00117019 danusertib final compound E05 A549 48 650 Metaphase +0.5142208918142528 7.7475655670411065e-59 BR00117017 briciclib final compound H01 A549 48 482 Metaphase +0.5471698113207547 1.2638985492025084e-58 BR00117016 colchicine final compound K17 A549 48 424 Metaphase +0.6110521397530461 3.1839032517438937e-58 BR00117054 fludarabine-phosphate final compound N12 A549 48 331 Metaphase +0.5348279582783839 4.277197122792923e-58 BR00117016 briciclib final compound H01 A549 48 439 Metaphase +0.6462826783012561 5.885686210015466e-58 BR00117053 CYT-997 final compound C09 A549 48 291 Metaphase +0.6134969325153374 1.368108628100154e-57 BR00117055 fludarabine-phosphate final compound N12 A549 48 326 Metaphase +0.5469879518072289 2.3928406588437715e-57 BR00117054 aminopurvalanol-a final compound K03 A549 48 415 Metaphase +0.7174774774774775 6.950367773404659e-56 BR00117008 fludarabine-phosphate final compound N12 A549 48 222 Metaphase +0.38562874251497004 9.671312452947468e-56 BR00117053 FK-866 final compound L09 A549 48 835 Metaphase +0.5173827500798978 2.3670131765802637e-55 BR00117019 CYT-997 final compound E06 A549 48 448 Metaphase +0.5377055467663838 6.714172588481038e-55 BR00117053 PF-431396 final compound L20 A549 48 409 Metaphase +0.5322195704057279 1.1720696964241725e-54 BR00117017 CYT-997 final compound E06 A549 48 419 Metaphase +0.43601895734597157 1.9353730764186155e-54 BR00117017 danusertib final compound N18 A549 48 633 Metaphase +0.4000726304321511 3.278610099304388e-54 BR00117050 FK-866 final compound L09 A549 48 751 Metaphase +0.5400164575965628 5.891715184330347e-54 BR00117055 aminopurvalanol-a final compound K03 A549 48 401 Metaphase +0.3941917237070839 6.417805924560823e-54 BR00117052 FK-866 final compound L09 A549 48 768 Metaphase +0.3038842345773039 6.637037037847342e-54 BR00117016 FK-866 final compound L09 A549 48 1313 Metaphase +0.34234451593137255 1.4692553677839177e-53 BR00117055 FK-866 final compound D08 A549 48 1024 Metaphase +0.6472923882740559 3.681857637802069e-53 BR00117053 CYT-997 final compound E06 A549 48 267 Metaphase +0.5367892976588629 2.3944743375830383e-52 BR00117054 epothilone-b final compound F07 A549 48 391 Metaphase +0.46111111111111114 3.5608021580428975e-52 BR00117016 danusertib final compound N18 A549 48 540 Metaphase +0.401524318378251 6.436112266538137e-52 BR00117051 FK-866 final compound L09 A549 48 712 Metaphase +0.33859822309970383 7.549921364501958e-52 BR00117055 fludarabine final compound B06 A549 48 1013 Metaphase +0.44069794999407513 2.2732976468465516e-51 BR00117015 KG-5 final compound C13 A549 48 580 Metaphase +0.45339747843397477 2.795409522539177e-51 BR00117016 geldanamycin final compound L01 A549 48 548 Metaphase +0.507096081705228 5.749156607283761e-51 BR00117016 ixabepilone final compound J21 A549 48 431 Metaphase +0.4143477074109543 6.02934015727293e-51 BR00117016 danusertib final compound E05 A549 48 657 Metaphase +0.3839817951613455 6.169745928751535e-51 BR00117052 FK-866 final compound D08 A549 48 765 Metaphase +0.552625780967219 1.202310842322847e-50 BR00117052 PF-431396 final compound L20 A549 48 359 Metaphase +0.39339752407152684 1.3451460573583608e-50 BR00117053 fludarabine final compound B06 A549 48 727 Metaphase +0.6152391380082616 1.7622190008703763e-50 BR00117050 epothilone-b final compound F07 A549 48 283 Metaphase +0.5882407502834175 1.854965637253198e-50 BR00117052 oxibendazole final compound M19 A549 48 310 Metaphase +0.6267156862745098 2.7939576978356373e-50 BR00117050 PF-431396 final compound L20 A549 48 270 Metaphase +0.49551569506726456 4.323684891306709e-50 BR00117019 colchicine final compound K17 A549 48 446 Metaphase 0.3617869495323461 3.4701543566291505e-75 BR00117016 ingenol-mebutate final compound M11 A549 48 1280 MetaphaseAlignment 0.35485616439221074 4.887416269029851e-71 BR00117015 ingenol-mebutate final compound M11 A549 48 1259 MetaphaseAlignment 0.5602728047740836 8.548315590508543e-67 BR00117015 fludarabine-phosphate final compound N12 A549 48 459 MetaphaseAlignment @@ -259,6 +2509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.3210514225861451 4.739026427617858e-60 BR00117015 NNC-55-0396 final compound A16 A549 48 1307 MetaphaseAlignment 0.3207203468826865 2.652656733262235e-59 BR00117016 NNC-55-0396 final compound A16 A549 48 1290 MetaphaseAlignment 0.2997587987638265 3.697610974440307e-59 BR00117017 ingenol-mebutate final compound M11 A549 48 1477 MetaphaseAlignment +0.2986763296490291 3.955469749858202e-59 BR00117017 NNC-55-0396 final compound A16 A549 48 1491 MetaphaseAlignment +0.28386096221915835 6.830348663970662e-58 BR00117015 fludarabine final compound B06 A549 48 1615 MetaphaseAlignment +0.6663005829179691 4.968035970957858e-57 BR00117053 fludarabine-phosphate final compound N12 A549 48 267 MetaphaseAlignment +0.33417494089834515 3.5033060052506534e-56 BR00117019 ingenol-mebutate final compound M11 A549 48 1128 MetaphaseAlignment +0.6289678940685652 1.6253266199822292e-55 BR00117050 fludarabine-phosphate final compound N12 A549 48 296 MetaphaseAlignment +0.25380738675148506 1.740369685068083e-55 BR00117015 desonide final compound E16 A549 48 1945 MetaphaseAlignment +0.5329149893440682 4.882955077352711e-54 BR00117019 fludarabine-phosphate final compound N12 A549 48 412 MetaphaseAlignment +0.47750392147727094 8.297879963888692e-53 BR00117017 fludarabine-phosphate final compound N12 A549 48 507 MetaphaseAlignment +0.27101148139268494 1.2910294869787434e-50 BR00117019 dexamethasone final compound A21 A549 48 1548 MetaphaseAlignment +0.35320088300220753 1.3976672546561057e-50 BR00117055 ingenol-mebutate final compound M11 A549 48 906 MetaphaseAlignment +0.5040257119038217 4.450067703271814e-50 BR00117016 fludarabine-phosphate final compound N12 A549 48 428 MetaphaseAlignment +0.6397671568627451 1.5687132516027642e-49 BR00117052 fludarabine-phosphate final compound N12 A549 48 255 MetaphaseAlignment +0.2763337893296854 1.5755660067895948e-49 BR00117016 dexamethasone final compound A21 A549 48 1462 MetaphaseAlignment +0.39216890114020797 4.2883729671789986e-48 BR00117051 NNC-55-0396 final compound A16 A549 48 694 MetaphaseAlignment +0.3405639913232104 8.778129151368518e-48 BR00117054 ingenol-mebutate final compound M11 A549 48 922 MetaphaseAlignment +0.22684703145576884 1.903938246983373e-47 BR00117017 dexamethasone final compound O02 A549 48 2079 MetaphaseAlignment +0.23249383442206598 2.4329758568695822e-46 BR00117017 desonide final compound E16 A549 48 1938 MetaphaseAlignment +0.23062933096594412 1.8314665697917707e-45 BR00117016 desonide final compound E16 A549 48 1932 MetaphaseAlignment +0.5284090909090909 2.7496409406226142e-45 BR00117015 azeliragon final compound C08 A549 48 352 MetaphaseAlignment +0.5394336935122434 4.873220416324702e-45 BR00117054 fludarabine-phosphate final compound N12 A549 48 331 MetaphaseAlignment +0.517542101042502 6.866137946217796e-43 BR00117019 azeliragon final compound C08 A549 48 348 MetaphaseAlignment +0.21699613359129163 6.098385495113153e-42 BR00117019 desonide final compound E16 A549 48 2011 MetaphaseAlignment +0.3784900708166196 3.5463364313409985e-41 BR00117050 NNC-55-0396 final compound A16 A549 48 635 MetaphaseAlignment +0.3955102473873141 4.180705188953793e-41 BR00117015 aminopurvalanol-a final compound K03 A549 48 582 MetaphaseAlignment +0.4021995161701044 6.240754381016947e-41 BR00117019 geldanamycin final compound L01 A549 48 560 MetaphaseAlignment +0.38490504077499865 1.343385670380167e-40 BR00117016 aminopurvalanol-a final compound K03 A549 48 605 MetaphaseAlignment +0.35346222405045935 2.7778659352050516e-40 BR00117015 AZ191 final compound I18 A549 48 715 MetaphaseAlignment +0.253510529527202 6.629590462551003e-40 BR00117015 halopemide final compound F11 A549 48 1394 MetaphaseAlignment +0.2364316905801622 1.0629209894814523e-39 BR00117017 dexamethasone final compound A21 A549 48 1603 MetaphaseAlignment +0.3195402298850575 1.1486022723482736e-39 BR00117015 thiostrepton final compound B02 A549 48 870 MetaphaseAlignment +0.3777658307243077 1.2257271407013811e-39 BR00117019 aminopurvalanol-a final compound K03 A549 48 618 MetaphaseAlignment +0.24138073571400617 4.7797107378596434e-39 BR00117017 fludarabine final compound B06 A549 48 1509 MetaphaseAlignment +0.50920245398773 7.550483947812167e-39 BR00117055 fludarabine-phosphate final compound N12 A549 48 326 MetaphaseAlignment +0.3405114401076716 1.428154811655388e-38 BR00117052 NNC-55-0396 final compound A16 A549 48 743 MetaphaseAlignment +0.3659305993690852 3.9087761236851166e-38 BR00117053 NNC-55-0396 final compound A16 A549 48 634 MetaphaseAlignment +0.39142667551426674 5.71909661821088e-38 BR00117016 geldanamycin final compound L01 A549 48 548 MetaphaseAlignment +0.3123886617754555 1.4718946339541188e-37 BR00117055 NNC-55-0396 final compound A16 A549 48 859 MetaphaseAlignment +0.5348154950956007 3.804900873659209e-37 BR00117051 aminopurvalanol-a final compound K03 A549 48 279 MetaphaseAlignment +0.3331446882671514 2.4708516296352977e-36 BR00117051 fludarabine final compound B06 A549 48 730 MetaphaseAlignment +0.1926405804164744 2.4148323116963256e-35 BR00117019 DDR1-IN-1 final compound A23 A549 48 2151 MetaphaseAlignment +0.4352078239608802 3.558935141528612e-35 BR00117015 7-hydroxystaurosporine final compound L04 A549 48 409 MetaphaseAlignment +0.39154093980826654 3.8170363858598897e-35 BR00117015 geldanamycin final compound L01 A549 48 505 MetaphaseAlignment +0.2946535349550088 5.515873089628341e-35 BR00117019 thiostrepton final compound B02 A549 48 901 MetaphaseAlignment +0.209485759573038 7.91175192704668e-35 BR00117015 dexamethasone final compound O02 A549 48 1788 MetaphaseAlignment +0.22610148533822486 7.995371074214177e-35 BR00117016 fludarabine final compound B06 A549 48 1533 MetaphaseAlignment +0.2773938795656466 1.0425147217519983e-34 BR00117055 fludarabine final compound B06 A549 48 1013 MetaphaseAlignment +0.3107575415871241 1.7197607832489043e-34 BR00117054 NNC-55-0396 final compound A16 A549 48 794 MetaphaseAlignment +0.24218543256355632 2.2185559015530213e-34 BR00117054 desonide final compound E16 A549 48 1319 MetaphaseAlignment +0.21672871979620445 4.914785717766636e-34 BR00117019 halopemide final compound F11 A549 48 1630 MetaphaseAlignment +0.2748138044726177 5.683326482052691e-34 BR00117054 dexamethasone final compound A21 A549 48 1010 MetaphaseAlignment +0.3794583028752437 2.5207972063225286e-33 BR00117015 NVP-HSP990 final compound E23 A549 48 512 MetaphaseAlignment +0.229755437557439 6.0439407036485395e-33 BR00117055 desonide final compound E16 A549 48 1400 MetaphaseAlignment +0.36174586138485054 6.266391434294893e-33 BR00117019 NVP-HSP990 final compound E23 A549 48 555 MetaphaseAlignment +0.3199972109887045 1.1039741870281877e-32 BR00117016 KU-60019 final compound I07 A549 48 707 MetaphaseAlignment +0.21830316597818575 2.2500889449210828e-32 BR00117015 JTE-607 final compound C14 A549 48 1524 MetaphaseAlignment +0.43848278793030177 4.476292319109364e-32 BR00117054 7-hydroxystaurosporine final compound L04 A549 48 364 MetaphaseAlignment +0.4665487421383648 8.319406142304073e-32 BR00117052 AZ191 final compound I18 A549 48 318 MetaphaseAlignment +0.15529784855553394 3.6672628689097603e-31 BR00117019 LY2109761 final compound M02 A549 48 2916 MetaphaseAlignment +0.500735171725018 5.197736656505163e-31 BR00117052 geldanamycin final compound L01 A549 48 268 MetaphaseAlignment +0.7082093253968254 5.289780391755051e-31 BR00117050 romidepsin final compound N19 A549 48 126 MetaphaseAlignment +0.27422520797332955 9.643969073394564e-31 BR00117055 dexamethasone final compound A21 A549 48 914 MetaphaseAlignment +0.40335885110675923 1.4520244723966807e-30 BR00117019 7-hydroxystaurosporine final compound L04 A549 48 411 MetaphaseAlignment +0.29962256897726675 1.497154197787077e-30 BR00117015 KU-60019 final compound I07 A549 48 758 MetaphaseAlignment +0.6929175475687104 2.2207496093956072e-30 BR00117055 romidepsin final compound N19 A549 48 132 MetaphaseAlignment +0.2096730611083857 3.313152658770362e-30 BR00117019 FK-866 final compound L09 A549 48 1543 MetaphaseAlignment +0.2330524237302753 3.534339258674183e-30 BR00117017 halopemide final compound F11 A549 48 1247 MetaphaseAlignment +0.26260856027198975 4.261528916828394e-30 BR00117054 FK-866 final compound L09 A549 48 974 MetaphaseAlignment +0.1949649326474144 4.5162933804488276e-30 BR00117019 dexamethasone final compound O02 A549 48 1776 MetaphaseAlignment +0.307850135975136 5.656381895890002e-30 BR00117016 AZ191 final compound I18 A549 48 704 MetaphaseAlignment +0.34584038334861733 5.845119693023061e-30 BR00117015 ganetespib final compound I17 A549 48 556 MetaphaseAlignment +0.6941437007874016 6.705309877924794e-30 BR00117053 romidepsin final compound N19 A549 48 127 MetaphaseAlignment +0.43530917350328835 7.132160686235229e-30 BR00117016 azeliragon final compound C08 A549 48 343 MetaphaseAlignment +0.18364274962368288 8.949725654690165e-30 BR00117015 DDR1-IN-1 final compound A23 A549 48 1993 MetaphaseAlignment +0.3456916996047431 9.333872646843241e-30 BR00117017 aminopurvalanol-a final compound K03 A549 48 552 MetaphaseAlignment +0.39759036144578314 1.1092851007014385e-29 BR00117054 aminopurvalanol-a final compound K03 A549 48 415 MetaphaseAlignment +0.20155517780365528 1.250643820123886e-29 BR00117016 halopemide final compound F11 A549 48 1638 MetaphaseAlignment +0.397512710391592 1.5380497643458398e-29 BR00117016 7-hydroxystaurosporine final compound L04 A549 48 413 MetaphaseAlignment +0.22990439648281374 1.8502509332096077e-29 BR00117015 FK-866 final compound D08 A549 48 1250 MetaphaseAlignment +0.29288796361187835 2.1688636319121587e-29 BR00117017 AZ191 final compound I18 A549 48 762 MetaphaseAlignment +0.29451640237259413 2.97094101588419e-29 BR00117050 fludarabine final compound B06 A549 48 751 MetaphaseAlignment +0.4421722335832765 4.5087554355961246e-29 BR00117053 aminopurvalanol-a final compound K03 A549 48 324 MetaphaseAlignment +0.260819925293349 4.7858350242285696e-29 BR00117055 FK-866 final compound L09 A549 48 956 MetaphaseAlignment +0.20704533978557998 5.250725328874659e-29 BR00117055 dexamethasone final compound O02 A549 48 1524 MetaphaseAlignment +0.7490196078431373 7.09236219190366e-29 BR00117054 romidepsin final compound N19 A549 48 102 MetaphaseAlignment +0.5555102040816327 1.2192893334278574e-28 BR00117009 fludarabine-phosphate final compound N12 A549 48 200 MetaphaseAlignment +0.49535423925667826 2.323609004289134e-28 BR00117051 ganetespib final compound M10 A549 48 246 MetaphaseAlignment +0.3043574029204836 2.496979660319196e-28 BR00117050 halopemide final compound F11 A549 48 678 MetaphaseAlignment +0.41081081081081083 2.528634969746889e-28 BR00117016 SU3327 final compound I20 A549 48 370 MetaphaseAlignment +0.3915211970074813 8.201926717271627e-28 BR00117017 7-hydroxystaurosporine final compound L04 A549 48 401 MetaphaseAlignment +0.67064468503937 9.217522558234962e-28 BR00117015 romidepsin final compound N19 A549 48 127 MetaphaseAlignment 0.3893585561318972 1.0002638399015749e-107 BR00117019 fludarabine final compound B06 A549 48 1588 OutOfFocus 0.37495912509537477 8.147188115736291e-102 BR00117015 fludarabine final compound B06 A549 48 1615 OutOfFocus 0.34652072438229187 5.466003178071385e-93 BR00117017 JTE-607 final compound C14 A549 48 1739 OutOfFocus @@ -269,6 +2609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.420533070088845 1.169399853203449e-80 BR00117055 fludarabine final compound B06 A549 48 1013 OutOfFocus 0.2886273298885212 7.413348460230648e-80 BR00117053 LY2109761 final compound M02 A549 48 2161 OutOfFocus 0.32464216430484305 1.1617872976684828e-78 BR00117016 JTE-607 final compound C14 A549 48 1678 OutOfFocus +0.2453890567134037 1.5954666040014809e-77 BR00117019 LY2109761 final compound M02 A549 48 2916 OutOfFocus +0.33509441546209673 7.536422318107597e-77 BR00117016 fludarabine final compound B06 A549 48 1533 OutOfFocus +0.5951596097376148 5.5154527068078695e-76 BR00117015 fludarabine-phosphate final compound N12 A549 48 459 OutOfFocus +0.351052733868878 6.960533051451683e-75 BR00117017 FK-866 final compound L09 A549 48 1362 OutOfFocus +0.2827271411044815 8.323885304053183e-74 BR00117017 dexamethasone final compound O02 A549 48 2079 OutOfFocus +0.40914809640825395 1.945406925023458e-73 BR00117054 FK-866 final compound L09 A549 48 974 OutOfFocus +0.2912843315735663 7.0063289509339e-73 BR00117017 desonide final compound E16 A549 48 1938 OutOfFocus +0.36022765787370103 1.6513453158154333e-72 BR00117015 FK-866 final compound D08 A549 48 1250 OutOfFocus +0.366085020933973 4.884133942673418e-72 BR00117055 JTE-607 final compound C14 A549 48 1202 OutOfFocus +0.3868033790774099 4.4212389381061376e-69 BR00117054 fludarabine final compound B06 A549 48 1027 OutOfFocus +0.32421340629274964 2.304800520076978e-68 BR00117016 dexamethasone final compound A21 A549 48 1462 OutOfFocus +0.30637260949569584 2.8277209336838617e-68 BR00117019 JTE-607 final compound C14 A549 48 1638 OutOfFocus +0.32591333076097617 3.022904313484315e-68 BR00117016 FK-866 final compound D08 A549 48 1443 OutOfFocus +0.3384451030394927 1.2343244394369442e-67 BR00117015 FK-866 final compound L09 A549 48 1319 OutOfFocus +0.3373952779893374 1.3293654084263883e-66 BR00117016 FK-866 final compound L09 A549 48 1313 OutOfFocus +0.32472123440419504 1.926724395029346e-66 BR00117017 FK-866 final compound D08 A549 48 1410 OutOfFocus +0.22907098176962434 2.1970970952599437e-66 BR00117015 LY2109761 final compound M02 A549 48 2866 OutOfFocus +0.5329520570283744 2.246587564178245e-66 BR00117017 fludarabine-phosphate final compound N12 A549 48 507 OutOfFocus +0.3797372855392157 2.962016279696455e-66 BR00117055 FK-866 final compound D08 A549 48 1024 OutOfFocus +0.2765081867430349 4.432465633337973e-66 BR00117015 desonide final compound E16 A549 48 1945 OutOfFocus +0.2667703133171683 8.93198479868765e-65 BR00117052 LY2109761 final compound M02 A549 48 2052 OutOfFocus +0.3067606024412856 1.1625843426333912e-64 BR00117019 FK-866 final compound L09 A549 48 1543 OutOfFocus +0.43867473717744504 1.3861395050103066e-63 BR00117051 fludarabine final compound B06 A549 48 730 OutOfFocus +0.29881472239550844 1.584909982397166e-63 BR00117017 dexamethasone final compound A21 A549 48 1603 OutOfFocus +0.562206572769953 6.280886989170527e-63 BR00117016 fludarabine-phosphate final compound N12 A549 48 428 OutOfFocus +0.5694293156523799 3.645069661147018e-62 BR00117019 fludarabine-phosphate final compound N12 A549 48 412 OutOfFocus +0.21581119611137017 1.092592648655604e-60 BR00117016 LY2109761 final compound M02 A549 48 2954 OutOfFocus +0.4295729551347529 1.265948235071844e-59 BR00117051 FK-866 final compound L09 A549 48 712 OutOfFocus +0.37470633941222176 3.9004657404158434e-59 BR00117054 FK-866 final compound D08 A549 48 935 OutOfFocus +0.414041527517677 5.683858227605729e-58 BR00117050 fludarabine final compound B06 A549 48 751 OutOfFocus +0.3748792664191678 1.4692335623208985e-57 BR00117055 dexamethasone final compound A21 A549 48 914 OutOfFocus +0.2988809854267869 2.2457243107107542e-57 BR00117019 FK-866 final compound D08 A549 48 1441 OutOfFocus +0.6419480981158905 9.516834140723884e-57 BR00117051 fludarabine-phosphate final compound N12 A549 48 290 OutOfFocus +0.35398738089864484 1.3674150146085124e-56 BR00117054 dexamethasone final compound A21 A549 48 1010 OutOfFocus +0.2828874637044141 3.764191267813243e-55 BR00117019 dexamethasone final compound A21 A549 48 1548 OutOfFocus +0.2523314709442645 1.9790410502362948e-54 BR00117016 desonide final compound E16 A549 48 1932 OutOfFocus +0.26110918831071117 4.6213061848300495e-54 BR00117015 dexamethasone final compound O02 A549 48 1788 OutOfFocus +0.39003831417624524 1.15856911653843e-53 BR00117051 JTE-607 final compound C14 A549 48 780 OutOfFocus +0.40440165061898214 1.571374562487002e-53 BR00117053 fludarabine final compound B06 A549 48 727 OutOfFocus +0.4609422694094227 2.666403089611691e-53 BR00117016 geldanamycin final compound L01 A549 48 548 OutOfFocus +0.5843154332580315 5.195304872471044e-53 BR00117054 fludarabine-phosphate final compound N12 A549 48 331 OutOfFocus +0.39701538685387944 1.2199902882612858e-52 BR00117053 FK-866 final compound D08 A549 48 740 OutOfFocus +0.2436365468978239 1.2899292208815746e-51 BR00117019 PP-2 final compound J10 A549 48 1961 OutOfFocus +0.24042468214086934 1.350563995753278e-51 BR00117019 desonide final compound E16 A549 48 2011 OutOfFocus +0.2341614906832298 7.737271123784019e-51 BR00117016 PP-2 final compound J10 A549 48 2093 OutOfFocus +0.20027474577238236 1.0210080020104028e-50 BR00117017 LY2109761 final compound M02 A549 48 2862 OutOfFocus +0.5766871165644172 1.8545306557658944e-50 BR00117055 fludarabine-phosphate final compound N12 A549 48 326 OutOfFocus +0.38259761147041715 2.239656878900309e-50 BR00117052 FK-866 final compound D08 A549 48 765 OutOfFocus +0.2524397291733058 2.748458703254839e-50 BR00117019 dexamethasone final compound O02 A549 48 1776 OutOfFocus +0.38610017303132366 2.8935189004780894e-50 BR00117050 FK-866 final compound L09 A549 48 751 OutOfFocus +0.39410001762942937 3.025377689109202e-50 BR00117015 AZ191 final compound I18 A549 48 715 OutOfFocus +0.6400888480392157 4.36981081872114e-50 BR00117052 fludarabine-phosphate final compound N12 A549 48 255 OutOfFocus +0.3652694610778443 6.468229337636684e-50 BR00117053 FK-866 final compound L09 A549 48 835 OutOfFocus +0.4414565826330532 1.5976934727874182e-49 BR00117019 geldanamycin final compound L01 A549 48 560 OutOfFocus +0.35517241379310344 4.081850452860631e-49 BR00117015 thiostrepton final compound B02 A549 48 870 OutOfFocus +0.2781854385785765 4.095230951474532e-48 BR00117055 desonide final compound E16 A549 48 1400 OutOfFocus +0.4178178534289311 5.2898566220725404e-48 BR00117016 aminopurvalanol-a final compound K03 A549 48 605 OutOfFocus +0.2475537890393188 1.8131094032229318e-47 BR00117051 LY2109761 final compound M02 A549 48 1746 OutOfFocus +0.4113985431622445 2.9758947730550995e-47 BR00117019 aminopurvalanol-a final compound K03 A549 48 618 OutOfFocus +0.3491329479768786 3.6240607547019665e-47 BR00117053 JTE-607 final compound C14 A549 48 865 OutOfFocus +0.42134828149222237 9.296658542202538e-47 BR00117015 aminopurvalanol-a final compound K03 A549 48 582 OutOfFocus +0.6062065275548422 1.7486449569678724e-46 BR00117053 fludarabine-phosphate final compound N12 A549 48 267 OutOfFocus +0.44709256639949707 3.9027995005491865e-46 BR00117015 geldanamycin final compound L01 A549 48 505 OutOfFocus +0.22103163068467088 4.140070718365946e-46 BR00117017 PP-2 final compound J10 A549 48 2132 OutOfFocus +0.27259684361549497 5.704345314043623e-46 BR00117054 dexamethasone final compound O02 A549 48 1394 OutOfFocus +0.3642981312472838 5.792659175937996e-46 BR00117052 FK-866 final compound L09 A549 48 768 OutOfFocus +0.2294759368396892 9.946012183394492e-46 BR00117016 dexamethasone final compound O02 A549 48 1963 OutOfFocus +0.4921531549977718 2.069427502944558e-45 BR00117055 geldanamycin final compound L01 A549 48 409 OutOfFocus +0.17093990739591883 5.574255038048072e-45 BR00117015 CC-401 final compound M09 A549 48 3491 OutOfFocus +0.2575224510265173 7.961395795584807e-45 BR00117055 dexamethasone final compound O02 A549 48 1524 OutOfFocus +0.3172656733179258 9.212326226778648e-45 BR00117054 JTE-607 final compound C14 A549 48 991 OutOfFocus +0.4212540201232192 1.1385281069890515e-44 BR00117015 ganetespib final compound I17 A549 48 556 OutOfFocus +0.382420449983418 1.4867653024934232e-44 BR00117051 FK-866 final compound D08 A549 48 676 OutOfFocus +0.4360265899122807 3.370085033443189e-44 BR00117015 NVP-HSP990 final compound E23 A549 48 512 OutOfFocus +0.4795180722891566 1.4462557323286564e-43 BR00117054 aminopurvalanol-a final compound K03 A549 48 415 OutOfFocus +0.35618927869618394 1.9020211558850985e-43 BR00117017 AZ191 final compound I18 A549 48 762 OutOfFocus +0.3608108108108108 3.4217679596041907e-43 BR00117052 fludarabine final compound B06 A549 48 740 OutOfFocus +0.16503496503496504 6.689834926919419e-43 BR00117019 CC-401 final compound M09 A549 48 3575 OutOfFocus +0.36330409356725146 9.424734407725515e-43 BR00117050 FK-866 final compound D08 A549 48 722 OutOfFocus +0.5550063486305097 1.6539901309056562e-42 BR00117050 fludarabine-phosphate final compound N12 A549 48 296 OutOfFocus +0.3228503336393794 3.342761082077681e-42 BR00117019 thiostrepton final compound B02 A549 48 901 OutOfFocus +0.37790637956149853 4.4258122672400694e-42 BR00117009 FK-866 final compound D08 A549 48 656 OutOfFocus +0.4583339908992872 9.510705186833502e-42 BR00117055 AZ191 final compound I18 A549 48 435 OutOfFocus +0.33707447655592376 2.282104052263358e-41 BR00117050 JTE-607 final compound C14 A549 48 815 OutOfFocus +0.2585097488723512 2.468977442065485e-41 BR00117052 PP-2 final compound J10 A549 48 1390 OutOfFocus +0.2638051064148724 8.031298761350706e-41 BR00117054 desonide final compound E16 A549 48 1319 OutOfFocus +0.4157832570500517 1.0424508887163923e-40 BR00117017 geldanamycin final compound L01 A549 48 520 OutOfFocus +0.4876489392618425 1.9599481715646483e-40 BR00117051 AZ191 final compound I18 A549 48 370 OutOfFocus +0.18521006813020438 3.993564797395184e-40 BR00117050 CC-401 final compound M09 A549 48 2642 OutOfFocus +0.5202437106918238 7.2920480260688006e-40 BR00117052 AZ191 final compound I18 A549 48 318 OutOfFocus 0.26192940840213197 1.6019885181521864e-88 BR00117019 LY2109761 final compound M02 A549 48 2916 Polylobed 0.3849138350142882 1.5834971518788366e-83 BR00117015 ingenol-mebutate final compound M11 A549 48 1259 Polylobed 0.35264087658269716 3.236997703113509e-82 BR00117017 ingenol-mebutate final compound M11 A549 48 1477 Polylobed @@ -279,6 +2709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.3137866500311915 4.02838962528427e-70 BR00117017 dexamethasone final compound A21 A549 48 1603 Polylobed 0.37152955082742317 9.509350350122245e-70 BR00117019 ingenol-mebutate final compound M11 A549 48 1128 Polylobed 0.28150491781094145 5.098860242720112e-68 BR00117017 desonide final compound E16 A549 48 1938 Polylobed +0.39913232104121477 5.462340642277176e-66 BR00117054 ingenol-mebutate final compound M11 A549 48 922 Polylobed +0.2721035225096202 2.4707908459533795e-64 BR00117019 PP-2 final compound J10 A549 48 1961 Polylobed +0.6726863372437493 8.532665923179442e-63 BR00117051 fludarabine-phosphate final compound N12 A549 48 290 Polylobed +0.21929159971375262 1.2913902208584676e-62 BR00117016 LY2109761 final compound M02 A549 48 2954 Polylobed +0.22241460278169123 1.5053800690794863e-62 BR00117017 LY2109761 final compound M02 A549 48 2862 Polylobed +0.3144374720196678 4.738428535423463e-62 BR00117019 NNC-55-0396 final compound A16 A549 48 1407 Polylobed +0.22087432029050252 8.267263842178311e-62 BR00117015 LY2109761 final compound M02 A549 48 2866 Polylobed +0.29772869549002373 3.970900356215428e-61 BR00117019 dexamethasone final compound A21 A549 48 1548 Polylobed +0.29352753234568313 6.191683013180226e-61 BR00117015 dexamethasone final compound A21 A549 48 1587 Polylobed +0.30506155950752395 1.9090436465772113e-60 BR00117016 dexamethasone final compound A21 A549 48 1462 Polylobed +0.2636029591369228 6.657984790688233e-60 BR00117015 desonide final compound E16 A549 48 1945 Polylobed +0.31868361172110216 3.6961712780219967e-59 BR00117015 NNC-55-0396 final compound A16 A549 48 1307 Polylobed +0.523221559155063 7.671787149213286e-58 BR00117015 fludarabine-phosphate final compound N12 A549 48 459 Polylobed +0.24442028533035212 3.13795767022321e-57 BR00117053 LY2109761 final compound M02 A549 48 2161 Polylobed +0.25649423753019546 3.0793510077153823e-56 BR00117016 desonide final compound E16 A549 48 1932 Polylobed +0.2463870225883956 3.6142358689804986e-56 BR00117016 PP-2 final compound J10 A549 48 2093 Polylobed +0.30979486531834666 4.1682947587951694e-55 BR00117016 NNC-55-0396 final compound A16 A549 48 1290 Polylobed +0.1884644191193698 9.518000188471546e-55 BR00117015 CC-401 final compound M09 A549 48 3491 Polylobed +0.2458822401246425 5.704800302019917e-54 BR00117019 desonide final compound E16 A549 48 2011 Polylobed +0.3641907402110698 8.778968063954122e-54 BR00117055 ingenol-mebutate final compound M11 A549 48 906 Polylobed +0.2755581743276338 1.3529320601020577e-53 BR00117019 fludarabine final compound B06 A549 48 1588 Polylobed +0.258174689287828 1.466429472132549e-52 BR00117019 dexamethasone final compound O02 A549 48 1776 Polylobed +0.21094470442502236 5.400960659669022e-52 BR00117050 CC-401 final compound M09 A549 48 2642 Polylobed +0.18153846153846154 7.170950491786572e-52 BR00117019 CC-401 final compound M09 A549 48 3575 Polylobed +0.40730902560247256 8.279673847580634e-52 BR00117051 NNC-55-0396 final compound A16 A549 48 694 Polylobed +0.25547998113983605 9.233810600041494e-52 BR00117015 dexamethasone final compound O02 A549 48 1788 Polylobed +0.21711434771441318 1.44245386987767e-51 BR00117054 CC-401 final compound M09 A549 48 2474 Polylobed +0.25725977055004506 2.781602188753804e-51 BR00117051 LY2109761 final compound M02 A549 48 1746 Polylobed +0.3612935538890543 1.7341887275012863e-50 BR00117055 NNC-55-0396 final compound A16 A549 48 859 Polylobed +0.33338861140821713 2.4175619776563446e-50 BR00117054 dexamethasone final compound A21 A549 48 1010 Polylobed +0.23040060248923183 4.629561786151785e-50 BR00117017 PP-2 final compound J10 A549 48 2132 Polylobed +0.26294262643433913 6.714025214427865e-50 BR00117050 LY2109761 final compound M02 A549 48 1625 Polylobed +0.3475449440491227 2.09178068191366e-49 BR00117055 dexamethasone final compound A21 A549 48 914 Polylobed +0.22569277019938855 1.3273329177230134e-48 BR00117019 DDR1-IN-1 final compound A23 A549 48 2151 Polylobed +0.22798963023142976 1.9337595597075882e-47 BR00117016 PP-1 final compound A22 A549 48 2061 Polylobed +0.23359988534057433 2.2571013545008375e-47 BR00117015 PP-2 final compound J10 A549 48 1962 Polylobed +0.21942176622068416 3.1945750043879343e-47 BR00117054 LY2109761 final compound M02 A549 48 2220 Polylobed +0.5817159441320515 5.487910050629065e-47 BR00117050 fludarabine-phosphate final compound N12 A549 48 296 Polylobed +0.6062910084199262 1.6135137792892147e-46 BR00117053 fludarabine-phosphate final compound N12 A549 48 267 Polylobed +0.4480113062790228 2.767354597050059e-46 BR00117017 fludarabine-phosphate final compound N12 A549 48 507 Polylobed +0.28022438937206146 4.565623663976542e-46 BR00117054 desonide final compound E16 A549 48 1319 Polylobed +0.17033712942579365 1.165170974771716e-45 BR00117016 CC-401 final compound M09 A549 48 3567 Polylobed +0.6122395833333333 4.7136982399661763e-45 BR00117052 fludarabine-phosphate final compound N12 A549 48 255 Polylobed +0.2676059430205249 1.3091494444760987e-44 BR00117055 desonide final compound E16 A549 48 1400 Polylobed +0.25692616968512555 1.339376144549425e-44 BR00117055 dexamethasone final compound O02 A549 48 1524 Polylobed +0.4735421877056733 5.050511361481258e-44 BR00117016 fludarabine-phosphate final compound N12 A549 48 428 Polylobed +0.48253611176888467 5.053777922308773e-44 BR00117019 fludarabine-phosphate final compound N12 A549 48 412 Polylobed +0.20893561103810776 5.097968820588323e-44 BR00117055 LY2109761 final compound M02 A549 48 2283 Polylobed +0.24615125722601383 1.6401563194579051e-43 BR00117015 fludarabine final compound B06 A549 48 1615 Polylobed +0.1960757807369266 3.943165097899403e-43 BR00117017 RGFP966 final compound H03 A549 48 2532 Polylobed +0.28145407956605534 7.003937418273674e-43 BR00117051 PP-2 final compound J10 A549 48 1213 Polylobed +0.2152308938079229 7.244940251910512e-43 BR00117052 CC-401 final compound M09 A549 48 2088 Polylobed +0.5142045454545454 8.825409918430266e-43 BR00117015 azeliragon final compound C08 A549 48 352 Polylobed +0.3422198646214833 7.541806914582644e-42 BR00117054 NNC-55-0396 final compound A16 A549 48 794 Polylobed +0.3816173921656019 7.94605766215498e-42 BR00117050 NNC-55-0396 final compound A16 A549 48 635 Polylobed +0.2492433147190733 1.456220366900399e-41 BR00117017 fludarabine final compound B06 A549 48 1509 Polylobed +0.2592250446414748 1.4582297400190068e-41 BR00117052 PP-2 final compound J10 A549 48 1390 Polylobed +0.30160480853942256 2.060790477646052e-41 BR00117052 PP-1 final compound A22 A549 48 1019 Polylobed +0.2178209723929391 3.199665069567885e-41 BR00117016 dexamethasone final compound O02 A549 48 1963 Polylobed +0.21975246543728355 1.8333668144505413e-40 BR00117019 PP-1 final compound A22 A549 48 1889 Polylobed +0.20973406924234822 8.964706824605036e-39 BR00117015 DDR1-IN-1 final compound A23 A549 48 1993 Polylobed +0.21167677181223635 9.577933406001573e-39 BR00117017 DDR1-IN-1 final compound A23 A549 48 1946 Polylobed +0.5027444362791795 1.3718190277111003e-38 BR00117054 fludarabine-phosphate final compound N12 A549 48 331 Polylobed +0.2634631317315659 3.146443129921494e-37 BR00117053 PP-2 final compound J10 A549 48 1207 Polylobed +0.4449877750611247 8.175194713435391e-37 BR00117015 7-hydroxystaurosporine final compound L04 A549 48 409 Polylobed +0.3580441640378549 1.7272083267370045e-36 BR00117053 NNC-55-0396 final compound A16 A549 48 634 Polylobed +0.27889207258834764 3.0048127864289667e-36 BR00117050 PP-2 final compound J10 A549 48 1047 Polylobed +0.22295186988438523 4.899979195690878e-36 BR00117019 halopemide final compound F11 A549 48 1630 Polylobed +0.4765437048917402 4.918383603994707e-36 BR00117019 azeliragon final compound C08 A549 48 348 Polylobed +0.24103299856527977 6.209292108870404e-36 BR00117054 dexamethasone final compound O02 A549 48 1394 Polylobed +0.16879971691858725 1.0153486372177288e-35 BR00117019 conivaptan final compound D18 A549 48 2838 Polylobed +0.30096520127663956 1.0978143755923303e-35 BR00117050 ingenol-mebutate final compound M11 A549 48 883 Polylobed +0.2523385177395251 1.97811369499906e-35 BR00117017 halopemide final compound F11 A549 48 1247 Polylobed +0.265677215639887 3.9178537233513603e-35 BR00117053 PP-1 final compound A22 A549 48 1113 Polylobed +0.1882255329339767 6.137912108290106e-35 BR00117017 GNF-5837 final compound A10 A549 48 2223 Polylobed +0.4815950920245399 1.3086443745141723e-34 BR00117055 fludarabine-phosphate final compound N12 A549 48 326 Polylobed +0.3729794293297943 1.8646437090318603e-34 BR00117016 geldanamycin final compound L01 A549 48 548 Polylobed +0.23546212008773232 2.3103238484872863e-34 BR00117015 halopemide final compound F11 A549 48 1394 Polylobed +0.32563514916456093 3.705114348779289e-34 BR00117015 AZ191 final compound I18 A549 48 715 Polylobed +0.23985707221183725 3.71205684225296e-34 BR00117050 dexamethasone final compound O02 A549 48 1337 Polylobed +0.14836659037383707 6.30242969020369e-34 BR00117017 CC-401 final compound M09 A549 48 3481 Polylobed +0.2734452122408687 9.996283528386507e-34 BR00117055 fludarabine final compound B06 A549 48 1013 Polylobed +0.2142517367330583 1.242809832493386e-33 BR00117054 PP-2 final compound J10 A549 48 1645 Polylobed +0.3647918258212376 1.3315441308237123e-33 BR00117019 geldanamycin final compound L01 A549 48 560 Polylobed +0.4226930152513204 1.8215547552036927e-33 BR00117019 7-hydroxystaurosporine final compound L04 A549 48 411 Polylobed +0.18544058273311773 2.700340752869635e-33 BR00117017 PP-1 final compound A22 A549 48 2187 Polylobed +0.2137443690427856 2.7100261799084987e-33 BR00117016 halopemide final compound F11 A549 48 1638 Polylobed +0.17669415651032908 4.187061435459108e-33 BR00117019 IWP-L6 final compound F20 A549 48 2396 Polylobed +0.19393125081580348 7.702756637813802e-33 BR00117015 PP-1 final compound A22 A549 48 1964 Polylobed +0.164599940826494 4.130468070656746e-32 BR00117017 conivaptan final compound D18 A549 48 2670 Polylobed 0.6246474700793933 1.9859078089745582e-53 BR00117051 fludarabine-phosphate final compound N12 A549 48 290 Prometaphase 0.24899228450452798 8.878357185465553e-44 BR00117019 fludarabine final compound B06 A549 48 1588 Prometaphase 0.5924172794117647 4.9629260036199436e-42 BR00117052 fludarabine-phosphate final compound N12 A549 48 255 Prometaphase @@ -289,6 +2809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5429444397510631 8.31972799037449e-37 BR00117053 fludarabine-phosphate final compound N12 A549 48 267 Prometaphase 0.41447380884721036 9.207587663674462e-36 BR00117015 fludarabine-phosphate final compound N12 A549 48 459 Prometaphase 0.17256970610399397 6.454482842953134e-35 BR00117019 RKI-1447 final compound J04 A549 48 2654 Prometaphase +0.21694353239491565 8.736461115921569e-34 BR00117015 fludarabine final compound B06 A549 48 1615 Prometaphase +0.1734150670257667 6.712233050505734e-33 BR00117015 RKI-1447 final compound J04 A549 48 2466 Prometaphase +0.4992538170129721 3.551311844427004e-32 BR00117051 aminopurvalanol-a final compound K03 A549 48 279 Prometaphase +0.263573543928924 2.4517126279496537e-31 BR00117055 fludarabine final compound B06 A549 48 1013 Prometaphase +0.30198326023519545 6.268523530886184e-31 BR00117015 KU-60019 final compound I07 A549 48 758 Prometaphase +0.44581439445487786 3.02871492000999e-30 BR00117054 fludarabine-phosphate final compound N12 A549 48 331 Prometaphase +0.29065349967002996 4.6874031911559486e-30 BR00117019 AMG900 final compound N09 A549 48 795 Prometaphase +0.2085519783219987 9.686438309559334e-30 BR00117016 fludarabine final compound B06 A549 48 1533 Prometaphase +0.3946246744020838 3.035166466688404e-29 BR00117019 fludarabine-phosphate final compound N12 A549 48 412 Prometaphase +0.2267536704730832 4.966752752706683e-28 BR00117016 cyclosporine final compound M15 A549 48 1226 Prometaphase +0.3665158371040724 8.611043224888067e-27 BR00117051 AMG900 final compound N09 A549 48 442 Prometaphase +0.4236726501552677 1.1783693068006434e-26 BR00117053 aminopurvalanol-a final compound K03 A549 48 324 Prometaphase +0.35413824022455265 8.493479928918852e-26 BR00117053 AMG900 final compound N09 A549 48 452 Prometaphase +0.4171779141104294 8.562515681762243e-26 BR00117055 fludarabine-phosphate final compound N12 A549 48 326 Prometaphase +0.2372809152872444 8.791257782136981e-26 BR00117054 fludarabine final compound B06 A549 48 1027 Prometaphase +0.34499572668795825 1.7039055488643523e-25 BR00117051 KU-60019 final compound I07 A549 48 470 Prometaphase +0.270481144343303 3.7763904427449914e-25 BR00117017 AMG900 final compound N09 A549 48 769 Prometaphase +0.21520915238572355 8.365963040782861e-25 BR00117055 JTE-607 final compound C14 A549 48 1202 Prometaphase +0.2730187583156869 2.1627297678029284e-24 BR00117051 fludarabine final compound B06 A549 48 730 Prometaphase +0.31215438844772914 3.089363248733989e-24 BR00117055 KU-60019 final compound I07 A549 48 553 Prometaphase +0.35468672970913817 3.407513007065804e-24 BR00117052 AMG900 final compound N09 A549 48 424 Prometaphase +0.32828620869792347 3.76250473917595e-24 BR00117050 AMG900 final compound N09 A549 48 496 Prometaphase +0.3319587628865979 4.667249307173886e-24 BR00117052 KU-60019 final compound I07 A549 48 485 Prometaphase +0.2666498145075728 5.4923385913732755e-24 BR00117050 fludarabine final compound B06 A549 48 751 Prometaphase +0.2726008344923505 6.565222288897124e-24 BR00117019 PF-431396 final compound L20 A549 48 719 Prometaphase +0.2739089614089614 1.0211173886227603e-23 BR00117015 PF-431396 final compound L20 A549 48 702 Prometaphase +0.14724375708040932 6.779879310749651e-23 BR00117017 RKI-1447 final compound J04 A549 48 2374 Prometaphase +0.28629708105373014 8.480997272441565e-23 BR00117019 aminopurvalanol-a final compound K03 A549 48 618 Prometaphase +0.2708984196285016 1.958897974706626e-22 BR00117017 KU-60019 final compound I07 A549 48 677 Prometaphase +0.17340073366563433 2.458172647920882e-22 BR00117054 RKI-1447 final compound J04 A549 48 1665 Prometaphase +0.42254901960784313 2.916775443609544e-22 BR00117050 PF-431396 final compound L20 A549 48 270 Prometaphase +0.2702406857896472 4.008227402956145e-22 BR00117016 AMG900 final compound N09 A549 48 674 Prometaphase +0.33321518116376414 5.146392166018601e-22 BR00117050 KU-60019 final compound I07 A549 48 439 Prometaphase +0.2 6.278061428557282e-22 BR00117017 cyclosporine final compound M15 A549 48 1230 Prometaphase +0.14515140977333285 6.734398783346664e-22 BR00117016 RKI-1447 final compound J04 A549 48 2336 Prometaphase +0.24970847799008825 8.624143551067835e-22 BR00117019 KU-60019 final compound I07 A549 48 776 Prometaphase +0.2554054054054054 1.310651314856805e-21 BR00117052 fludarabine final compound B06 A549 48 740 Prometaphase +0.280693448634448 1.4059987587162831e-21 BR00117016 aminopurvalanol-a final compound K03 A549 48 605 Prometaphase +0.2768 1.7679565516908736e-21 BR00117016 PF-431396 final compound L20 A549 48 625 Prometaphase +0.25152731531124783 1.8551009477775724e-21 BR00117017 PF-431396 final compound L20 A549 48 752 Prometaphase +0.2530949105914718 7.394060315563321e-21 BR00117053 fludarabine final compound B06 A549 48 727 Prometaphase +0.1268809527641112 1.4529588677173384e-20 BR00117017 LY2109761 final compound M02 A549 48 2862 Prometaphase +0.22857627351310758 2.9505871363847426e-20 BR00117052 cyclosporine final compound M15 A549 48 861 Prometaphase +0.25104305806552996 3.100687278308407e-20 BR00117051 FK-866 final compound L09 A549 48 712 Prometaphase +0.327710843373494 4.0503802507598437e-20 BR00117054 aminopurvalanol-a final compound K03 A549 48 415 Prometaphase +0.12334890293537769 9.051723228388838e-20 BR00117019 LY2109761 final compound M02 A549 48 2916 Prometaphase +0.3830555947841642 9.595355876591097e-20 BR00117051 geldanamycin final compound L01 A549 48 292 Prometaphase +0.3041016001542317 3.873472228069521e-19 BR00117053 KU-60019 final compound I07 A549 48 455 Prometaphase +0.12022229400600092 4.724735299690063e-19 BR00117016 LY2109761 final compound M02 A549 48 2954 Prometaphase +0.34173669467787116 7.10260167798279e-19 BR00117051 PF-431396 final compound L20 A549 48 357 Prometaphase +0.12087928398255506 1.0470800189523724e-18 BR00117015 LY2109761 final compound M02 A549 48 2866 Prometaphase +0.13811228849016552 3.25793222406025e-18 BR00117017 PP-2 final compound J10 A549 48 2132 Prometaphase +0.38514675692171113 3.492746903208626e-18 BR00117052 geldanamycin final compound L01 A549 48 268 Prometaphase +0.19047619047619047 4.615436736304338e-18 BR00117019 cyclosporine final compound M15 A549 48 1113 Prometaphase +0.3299812725241175 9.823236818833763e-18 BR00117052 PF-431396 final compound L20 A549 48 359 Prometaphase +0.3279594155086289 1.062351130594458e-17 BR00117017 BI-2536 final compound E21 A549 48 359 Prometaphase +0.3221672888709515 1.2308798343141383e-17 BR00117016 BI-2536 final compound E21 A549 48 374 Prometaphase +0.2338785186365719 1.5395341611558368e-17 BR00117016 KU-60019 final compound I07 A549 48 707 Prometaphase +0.31456935909279565 1.5627371357626296e-17 BR00117054 geldanamycin final compound L01 A549 48 387 Prometaphase +0.14553290499355162 2.1246553372889147e-17 BR00117016 AC-710 final compound I03 A549 48 1829 Prometaphase +0.22430448619238272 2.5064974103430266e-17 BR00117052 FK-866 final compound D08 A549 48 765 Prometaphase +0.13728418889593055 2.852204135552367e-17 BR00117015 NVS-PAK1-1 final compound N14 A549 48 2040 Prometaphase +0.19128444045874435 3.44954047856097e-17 BR00117015 cyclosporine final compound M15 A549 48 1048 Prometaphase +0.14818113660020474 3.581629360033941e-17 BR00117017 JTE-607 final compound C14 A549 48 1739 Prometaphase +0.2913402166211155 3.83672139029886e-17 BR00117015 BAX-channel-blocker final compound I19 A549 48 444 Prometaphase +0.15301027241369042 6.547552620253722e-17 BR00117052 RKI-1447 final compound J04 A549 48 1607 Prometaphase +0.3004098950093485 7.083266292017572e-17 BR00117053 PF-431396 final compound L20 A549 48 409 Prometaphase +0.38317847464188926 7.5880487772271e-17 BR00117051 ganetespib final compound M10 A549 48 246 Prometaphase +0.23520710059171598 8.288902220032092e-17 BR00117017 NVP-ADW742 final compound D16 A549 48 676 Prometaphase +0.1509155266044427 9.893491477932006e-17 BR00117019 JTE-607 final compound C14 A549 48 1638 Prometaphase +0.22592902501088924 1.222325359708796e-16 BR00117053 cyclosporine final compound M15 A549 48 724 Prometaphase +0.3375393081761006 1.3513615228745032e-16 BR00117052 AZ191 final compound I18 A549 48 318 Prometaphase +0.248155211245289 1.379679180101636e-16 BR00117055 AMG900 final compound N09 A549 48 593 Prometaphase +0.16119828815977175 2.6049627903881166e-16 BR00117050 RKI-1447 final compound J04 A549 48 1402 Prometaphase +0.3548819608039697 2.7703358792283253e-16 BR00117052 aminopurvalanol-a final compound K03 A549 48 284 Prometaphase +0.20707911100875173 3.7027571474879346e-16 BR00117054 cyclosporine final compound M15 A549 48 832 Prometaphase +0.27545341270940055 5.143559761515502e-16 BR00117054 PF-431396 final compound L20 A549 48 465 Prometaphase +0.2169923168395793 5.55142035371812e-16 BR00117050 FK-866 final compound L09 A549 48 751 Prometaphase +0.14444444444444443 5.709659839026177e-16 BR00117019 AC-710 final compound I03 A549 48 1710 Prometaphase +0.18433619866284623 5.874551745034907e-16 BR00117053 AC-710 final compound I03 A549 48 1047 Prometaphase +0.25489869090302675 6.907752047534246e-16 BR00117054 AMG900 final compound N09 A549 48 537 Prometaphase +0.25142715723477976 1.019723028019658e-15 BR00117008 fludarabine final compound B06 A549 48 550 Prometaphase +0.2511877903118779 1.1246037184315874e-15 BR00117016 geldanamycin final compound L01 A549 48 548 Prometaphase +0.26932737046573607 1.3281060235479078e-15 BR00117055 PF-431396 final compound L20 A549 48 471 Prometaphase +0.12352168199737187 1.3735138926696593e-15 BR00117055 LY2109761 final compound M02 A549 48 2283 Prometaphase +0.24923583662714097 1.3960332136950848e-15 BR00117017 aminopurvalanol-a final compound K03 A549 48 552 Prometaphase +0.12440840299271318 1.920681190005541e-15 BR00117054 LY2109761 final compound M02 A549 48 2220 Prometaphase +0.16757649100684063 2.1886677628230576e-15 BR00117016 WH-4-023 final compound A18 A549 48 1215 Prometaphase +0.20793299931230966 2.783268972892108e-15 BR00117051 JTE-607 final compound C14 A549 48 780 Prometaphase +0.24341100076394195 5.131260471563318e-15 BR00117019 geldanamycin final compound L01 A549 48 560 Prometaphase 0.6885003458721942 6.051060383965012e-180 BR00117019 AMG900 final compound N09 A549 48 795 SmallIrregular 0.6814044213263979 2.2316173124310273e-170 BR00117017 AMG900 final compound N09 A549 48 769 SmallIrregular 0.6799323361823362 3.338950277884725e-155 BR00117015 AMG900 final compound N09 A549 48 702 SmallIrregular @@ -299,6 +2909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.7191785294501764 4.922908231182662e-124 BR00117050 AMG900 final compound N09 A549 48 496 SmallIrregular 0.5935224899825047 1.5733923787939487e-123 BR00117017 PF-431396 final compound L20 A549 48 752 SmallIrregular 0.7464482588625465 3.4132974593053412e-115 BR00117052 AMG900 final compound N09 A549 48 424 SmallIrregular +0.4128093466509009 1.9318426994534442e-113 BR00117017 ingenol-mebutate final compound M11 A549 48 1477 SmallIrregular +0.7152547658960664 2.8097689661861416e-112 BR00117053 AMG900 final compound N09 A549 48 452 SmallIrregular +0.608 5.353218461277984e-108 BR00117016 PF-431396 final compound L20 A549 48 625 SmallIrregular +0.6383237444064593 4.3506745159980923e-103 BR00117054 AMG900 final compound N09 A549 48 537 SmallIrregular +0.6923076923076923 1.4327837302831405e-101 BR00117051 AMG900 final compound N09 A549 48 442 SmallIrregular +0.5766192733017378 1.2400407531013477e-97 BR00117017 danusertib final compound N18 A549 48 633 SmallIrregular +0.6182314885288681 2.674723722759577e-97 BR00117015 epothilone-b final compound F07 A549 48 544 SmallIrregular +0.6171920769981867 6.798388924203566e-96 BR00117016 epothilone-b final compound F07 A549 48 535 SmallIrregular +0.31088802421689826 9.396399243788987e-93 BR00117053 LY2109761 final compound M02 A549 48 2161 SmallIrregular +0.39685003409976616 9.451171292291879e-91 BR00117016 ingenol-mebutate final compound M11 A549 48 1280 SmallIrregular +0.5765778890659382 1.2685020520242246e-88 BR00117015 danusertib final compound E05 A549 48 575 SmallIrregular +0.5951492537313433 1.6510947910384503e-88 BR00117017 epothilone-b final compound F07 A549 48 536 SmallIrregular +0.2615521558163652 3.966321853259394e-88 BR00117019 LY2109761 final compound M02 A549 48 2916 SmallIrregular +0.5597511975250243 6.056884348824988e-88 BR00117017 danusertib final compound E05 A549 48 607 SmallIrregular +0.669495181935855 2.72126327687197e-87 BR00117053 PF-431396 final compound L20 A549 48 409 SmallIrregular +0.5611355453261018 2.5921878256341076e-86 BR00117015 danusertib final compound N18 A549 48 592 SmallIrregular +0.41216075650118206 4.236420919051124e-86 BR00117019 ingenol-mebutate final compound M11 A549 48 1128 SmallIrregular +0.5240778522620552 2.6502413106603666e-83 BR00117016 danusertib final compound E05 A549 48 657 SmallIrregular +0.5491525423728814 4.580897904909604e-82 BR00117019 epothilone-b final compound F07 A549 48 590 SmallIrregular +0.38100241062442625 7.172346325740473e-82 BR00117015 ingenol-mebutate final compound M11 A549 48 1259 SmallIrregular +0.25143241446633985 5.217467835368961e-80 BR00117015 LY2109761 final compound M02 A549 48 2866 SmallIrregular +0.6025116321091385 6.907304910227707e-80 BR00117055 PF-431396 final compound L20 A549 48 471 SmallIrregular +0.67687235415388 3.9998654529635677e-78 BR00117052 PF-431396 final compound L20 A549 48 359 SmallIrregular +0.5072845798269527 1.647080757532147e-76 BR00117019 danusertib final compound E05 A549 48 650 SmallIrregular +0.589750334579353 7.003502521898302e-76 BR00117054 PF-431396 final compound L20 A549 48 465 SmallIrregular +0.5137184609490449 1.667257412144717e-73 BR00117016 aminopurvalanol-a final compound K03 A549 48 605 SmallIrregular +0.2803817810107926 1.4132529147864825e-71 BR00117052 LY2109761 final compound M02 A549 48 2052 SmallIrregular +0.6498599439775911 2.058180143459115e-71 BR00117051 PF-431396 final compound L20 A549 48 357 SmallIrregular +0.3604537412275357 2.1618983894748936e-70 BR00117015 polydatin final compound K08 A549 48 1211 SmallIrregular +0.6536622744915127 2.2968578464071243e-70 BR00117053 danusertib final compound E05 A549 48 347 SmallIrregular +0.7000745503680924 8.872563820302858e-70 BR00117053 danusertib final compound N18 A549 48 292 SmallIrregular +0.7261411956858438 1.0421028856822573e-68 BR00117053 fludarabine-phosphate final compound N12 A549 48 267 SmallIrregular +0.5259259259259259 1.3276878038081682e-68 BR00117016 danusertib final compound N18 A549 48 540 SmallIrregular +0.6954716582808487 1.6791776183645807e-68 BR00117053 CYT-997 final compound C09 A549 48 291 SmallIrregular +0.6759558899309492 2.133305993698663e-68 BR00117052 oxibendazole final compound M19 A549 48 310 SmallIrregular +0.7195261437908497 3.4866985759453565e-68 BR00117050 PF-431396 final compound L20 A549 48 270 SmallIrregular +0.4890684460748659 1.600641090117302e-67 BR00117019 aminopurvalanol-a final compound K03 A549 48 618 SmallIrregular +0.6678113195766865 3.474239410819376e-66 BR00117053 oxibendazole final compound M19 A549 48 309 SmallIrregular +0.35131682917104645 5.373806562723981e-65 BR00117017 polydatin final compound K08 A549 48 1175 SmallIrregular +0.22285534290567727 9.45695660742314e-65 BR00117016 LY2109761 final compound M02 A549 48 2954 SmallIrregular +0.6717357635069919 1.3274042370776644e-64 BR00117052 epothilone-b final compound F07 A549 48 298 SmallIrregular +0.35144262701905743 1.3775042246684986e-64 BR00117019 polydatin final compound K08 A549 48 1170 SmallIrregular +0.6265459067078909 2.7067778510065254e-64 BR00117009 AMG900 final compound N09 A549 48 346 SmallIrregular +0.659227921734532 5.351025589856505e-64 BR00117052 briciclib final compound H01 A549 48 305 SmallIrregular +0.6224492338358042 2.02207451267341e-63 BR00117052 danusertib final compound N18 A549 48 349 SmallIrregular +0.5007312252964427 3.244975302124287e-63 BR00117017 aminopurvalanol-a final compound K03 A549 48 552 SmallIrregular +0.6664701614366044 6.53550664540255e-63 BR00117050 fludarabine-phosphate final compound N12 A549 48 296 SmallIrregular +0.6789304732991589 1.4721921507525945e-62 BR00117050 epothilone-b final compound F07 A549 48 283 SmallIrregular +0.38611713665943603 1.1464647462351811e-61 BR00117054 ingenol-mebutate final compound M11 A549 48 922 SmallIrregular +0.633372641509434 8.705263639546394e-61 BR00117052 danusertib final compound E05 A549 48 318 SmallIrregular +0.49847036998144845 9.733322274435679e-61 BR00117019 danusertib final compound N18 A549 48 535 SmallIrregular +0.4764814061643472 1.319661309764739e-60 BR00117015 aminopurvalanol-a final compound K03 A549 48 582 SmallIrregular +0.6275278345830493 2.3114858310877884e-60 BR00117053 aminopurvalanol-a final compound K03 A549 48 324 SmallIrregular +0.7081961816984859 3.4819774763878807e-60 BR00117053 briciclib final compound H01 A549 48 245 SmallIrregular +0.5208333333333334 8.673361747363906e-60 BR00117015 oxibendazole final compound M19 A549 48 480 SmallIrregular +0.5462627664418761 1.3954452335111261e-59 BR00117016 ixabepilone final compound J21 A549 48 431 SmallIrregular +0.5053891192595008 1.9570655459594032e-59 BR00117017 fludarabine-phosphate final compound N12 A549 48 507 SmallIrregular +0.5298759117173439 1.9916755066053207e-59 BR00117015 fludarabine-phosphate final compound N12 A549 48 459 SmallIrregular +0.3819901285633613 2.388364924152798e-59 BR00117055 ingenol-mebutate final compound M11 A549 48 906 SmallIrregular +0.2163669284895371 3.6095375554518457e-59 BR00117017 LY2109761 final compound M02 A549 48 2862 SmallIrregular +0.6491764427064818 1.1953554102241019e-58 BR00117051 fludarabine-phosphate final compound N12 A549 48 290 SmallIrregular +0.6871170343137255 1.5489470312867384e-58 BR00117052 fludarabine-phosphate final compound N12 A549 48 255 SmallIrregular +0.6172839506172839 5.300834747783221e-58 BR00117050 danusertib final compound E05 A549 48 324 SmallIrregular +0.5646009574398321 8.594291473318786e-58 BR00117054 epothilone-b final compound F07 A549 48 391 SmallIrregular +0.5752688172043011 3.135623347012979e-57 BR00117054 danusertib final compound E05 A549 48 372 SmallIrregular +0.6769478838444356 3.2913187502922155e-57 BR00117053 colchicine final compound K17 A549 48 261 SmallIrregular +0.6316556291390728 3.298970310859097e-57 BR00117051 epothilone-b final compound F07 A549 48 300 SmallIrregular +0.27094139937265016 6.433846825053368e-57 BR00117051 LY2109761 final compound M02 A549 48 1746 SmallIrregular +0.31836174067459094 2.2393810653170724e-56 BR00117016 polydatin final compound K08 A549 48 1248 SmallIrregular +0.6216388835664559 3.351789469236748e-56 BR00117008 AMG900 final compound N09 A549 48 307 SmallIrregular +0.6522481128979324 5.0763854233267965e-56 BR00117052 colchicine final compound K17 A549 48 277 SmallIrregular +0.6622595815381149 8.7489591355952e-56 BR00117053 CYT-997 final compound E06 A549 48 267 SmallIrregular +0.2518755488255458 4.1109724316894026e-55 BR00117015 PP-2 final compound J10 A549 48 1962 SmallIrregular +0.6150255129736185 2.0211031379069272e-54 BR00117050 danusertib final compound N18 A549 48 305 SmallIrregular +0.4541674773628676 2.6631591281916084e-54 BR00117052 polydatin final compound K08 A549 48 575 SmallIrregular +0.6361688286840393 4.2252421651141933e-54 BR00117051 aminopurvalanol-a final compound K03 A549 48 279 SmallIrregular +0.6759441384736428 4.689750270809621e-54 BR00117053 epothilone-b final compound F07 A549 48 246 SmallIrregular +0.6110018167940573 8.002285794918855e-54 BR00117051 danusertib final compound E05 A549 48 303 SmallIrregular +0.44692834544379934 1.4220999778837795e-53 BR00117053 polydatin final compound K08 A549 48 588 SmallIrregular +0.49131304940433573 1.5791588181584568e-53 BR00117017 briciclib final compound H01 A549 48 482 SmallIrregular +0.5214927870711972 4.0204540963876227e-53 BR00117015 ixabepilone final compound J21 A549 48 423 SmallIrregular +0.6330887776095648 8.306495391647451e-53 BR00117052 ixabepilone final compound J21 A549 48 279 SmallIrregular +0.652677537200392 1.3855784038140186e-52 BR00117050 oxibendazole final compound M19 A549 48 258 SmallIrregular +0.26914784908155076 2.672689090074712e-52 BR00117050 LY2109761 final compound M02 A549 48 1625 SmallIrregular +0.18437423195205732 2.7013493753509598e-52 BR00117015 CC-401 final compound M09 A549 48 3491 SmallIrregular +0.5050109850422849 2.8062508492932197e-52 BR00117017 ixabepilone final compound J21 A549 48 446 SmallIrregular +0.5026534645519206 1.0739949374263975e-51 BR00117016 oxibendazole final compound M19 A549 48 446 SmallIrregular +0.5204819277108433 1.1460523391293903e-51 BR00117054 aminopurvalanol-a final compound K03 A549 48 415 SmallIrregular +0.6491974708171206 1.1720550905069804e-51 BR00117050 colchicine final compound K17 A549 48 256 SmallIrregular +0.4372931605074462 3.071735963908529e-51 BR00117051 polydatin final compound K08 A549 48 588 SmallIrregular 0.6636792452830189 4.462712607393618e-56 BR00117024 SU3327 final compound I20 U2OS 24 265 ADCCM 0.5187311062641106 4.163453064936582e-35 BR00116995 SU3327 final compound I20 U2OS 24 281 ADCCM 0.5610580824670557 1.032155668994775e-33 BR00117025 SU3327 final compound I20 U2OS 24 226 ADCCM @@ -309,6 +3009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.545 1.3166445983509098e-27 BR00117024 AZD7762 final compound I05 U2OS 24 200 ADCCM 0.44604616185572976 5.016357621152817e-27 BR00117025 delanzomib final compound L11 U2OS 24 295 ADCCM 0.4430049222769142 6.274915425618467e-27 BR00117026 puromycin final compound C22 U2OS 24 299 ADCCM +0.4930209371884347 1.372891309508193e-26 BR00117025 AZD7762 final compound I05 U2OS 24 236 ADCCM +0.4642857142857143 6.788225072646894e-25 BR00116995 colchicine final compound K17 U2OS 24 252 ADCCM +0.44925307244271656 1.1838786296917505e-24 BR00117026 delanzomib final compound L11 U2OS 24 267 ADCCM +0.42854911572472126 1.6937595203245577e-24 BR00117024 briciclib final compound H01 U2OS 24 289 ADCCM +0.48448610213316096 2.4099726342961785e-24 BR00117024 puromycin final compound C22 U2OS 24 224 ADCCM +0.4295754956786985 9.505475445832062e-24 BR00117026 CYT-997 final compound E06 U2OS 24 280 ADCCM +0.4834175084175084 1.0298210617130252e-23 BR00117024 CYT-997 final compound E06 U2OS 24 220 ADCCM +0.4627335940895263 3.4214369019771567e-23 BR00117024 colchicine final compound K17 U2OS 24 234 ADCCM +0.406380186041203 1.6547121190211476e-22 BR00117025 thiostrepton final compound B02 U2OS 24 297 ADCCM +0.4545849630595393 2.4452257184141845e-22 BR00117024 AZD7762 final compound K11 U2OS 24 234 ADCCM +0.4143140832975526 1.2357219693863427e-21 BR00116995 puromycin final compound C22 U2OS 24 272 ADCCM +0.4801980198019802 1.858811185006482e-21 BR00117026 AZD7762 final compound I05 U2OS 24 202 ADCCM +0.40770300259351355 7.036254691441187e-21 BR00117025 puromycin final compound C22 U2OS 24 274 ADCCM +0.2503364737550471 7.525096575165545e-21 BR00117024 RKI-1447 final compound J04 U2OS 24 743 ADCCM +0.39139719341061624 9.089011896068428e-21 BR00116995 briciclib final compound H01 U2OS 24 297 ADCCM +0.44030264910463224 1.0762738553899288e-20 BR00117024 oxibendazole final compound M19 U2OS 24 232 ADCCM +0.42520325203252035 2.4809923061609512e-20 BR00117025 colchicine final compound K17 U2OS 24 245 ADCCM +0.41542359915853894 6.641250894552927e-20 BR00117024 CYT-997 final compound C09 U2OS 24 249 ADCCM +0.4477577438742487 2.2669221739656285e-19 BR00117026 colchicine final compound K17 U2OS 24 210 ADCCM +0.380751062824752 2.947870138240881e-19 BR00117025 CYT-997 final compound C09 U2OS 24 290 ADCCM +0.4065040650406504 1.460218839646217e-18 BR00117026 CYT-997 final compound C09 U2OS 24 246 ADCCM +0.37447792060338186 1.9446937517553755e-17 BR00116995 delanzomib final compound L11 U2OS 24 271 ADCCM +0.5193732193732193 6.392191388420793e-17 BR00117026 LDN-212854 final compound K01 U2OS 24 135 ADCCM +0.22620689655172413 1.1500299948339794e-16 BR00116995 RKI-1447 final compound J04 U2OS 24 725 ADCCM +0.36691072937200786 1.4517204909741553e-16 BR00117025 briciclib final compound H01 U2OS 24 268 ADCCM +0.35897810218978105 2.5795146405784115e-16 BR00117026 AZD7762 final compound K11 U2OS 24 275 ADCCM +0.4073121191604604 2.740422633215647e-16 BR00116995 thiostrepton final compound B02 U2OS 24 211 ADCCM +0.34210526315789475 3.6292768684701293e-16 BR00117026 NSC-663284 final compound G06 U2OS 24 304 ADCCM +0.3739795918367347 1.1723518710656326e-15 BR00117024 NSC-632839 final compound M16 U2OS 24 240 ADCCM +0.37341394237945963 8.139870799424343e-15 BR00117024 ryuvidine final compound A14 U2OS 24 231 ADCCM +0.34425942922075087 2.154904224047542e-14 BR00117026 NSC-632839 final compound M16 U2OS 24 263 ADCCM +0.4032373032373032 6.648900227113234e-14 BR00117025 CYT-997 final compound E06 U2OS 24 182 ADCCM +0.32264646223601 9.133179231567671e-14 BR00116995 NSC-632839 final compound M16 U2OS 24 289 ADCCM +0.4717781007751938 1.1166033310977623e-13 BR00117024 LDN-212854 final compound K01 U2OS 24 129 ADCCM +0.38321046858658775 1.990277378678668e-13 BR00117026 ponatinib final compound C20 U2OS 24 199 ADCCM +0.4146341463414634 5.24123818825375e-13 BR00117024 ponatinib final compound C20 U2OS 24 164 ADCCM +0.32530209254347187 8.128350083392872e-13 BR00117026 briciclib final compound H01 U2OS 24 261 ADCCM +0.313741649497409 8.192000377008551e-13 BR00117024 NSC-663284 final compound G06 U2OS 24 285 ADCCM +0.38091520538073503 2.4458005173402993e-12 BR00116995 ponatinib final compound C20 U2OS 24 181 ADCCM +0.47575757575757577 2.6614661628049293e-12 BR00117025 LDN-212854 final compound K01 U2OS 24 110 ADCCM +0.3120811039143903 5.765605255256393e-12 BR00117026 oxibendazole final compound M19 U2OS 24 268 ADCCM +0.32413731450026817 1.474012509143989e-11 BR00117025 ponatinib final compound C20 U2OS 24 235 ADCCM +0.17237308146399055 2.104456269381311e-11 BR00117025 RKI-1447 final compound J04 U2OS 24 847 ADCCM +0.19656347352024922 2.5424726010399178e-11 BR00117025 KU-60019 final compound I07 U2OS 24 642 ADCCM +0.1941440637360366 2.632828544809157e-11 BR00117024 AZ191 final compound I18 U2OS 24 653 ADCCM +0.2799122807017544 6.155867855252866e-11 BR00117025 NSC-663284 final compound G06 U2OS 24 304 ADCCM +0.2864686973825195 1.1581326785862021e-10 BR00117025 oxibendazole final compound M19 U2OS 24 278 ADCCM +0.18318243769470405 6.629258243464695e-10 BR00117026 KU-60019 final compound I07 U2OS 24 642 ADCCM +0.16462040073917122 8.212559314584861e-10 BR00117026 RKI-1447 final compound J04 U2OS 24 786 ADCCM +0.1893576317542194 8.255999210516363e-10 BR00117026 BMS-536924 final compound B15 U2OS 24 593 ADCCM +0.28995095618972383 1.2822958458279687e-09 BR00117025 AZD7762 final compound K11 U2OS 24 247 ADCCM +0.16329113924050634 1.31093345442593e-09 BR00116995 AZ191 final compound I18 U2OS 24 790 ADCCM +0.33869731800766284 1.5860195006571083e-09 BR00117026 ryuvidine final compound A14 U2OS 24 174 ADCCM +0.16078155444901493 6.306848738365049e-09 BR00117024 NVS-PAK1-1 final compound N14 U2OS 24 745 ADCCM +0.25755135168883064 9.37026246502066e-09 BR00117024 buparlisib final compound L12 U2OS 24 285 ADCCM +0.27692089494025457 1.3289488451321838e-08 BR00116995 oxibendazole final compound M19 U2OS 24 238 ADCCM +0.25726226983942135 1.3367845979240696e-08 BR00116995 buparlisib final compound L12 U2OS 24 279 ADCCM +0.23613403521793908 2.4795624323605965e-08 BR00117024 BI-2536 final compound E21 U2OS 24 317 ADCCM +0.17641291277402646 3.2962322546267216e-08 BR00116995 UNC1999 final compound H19 U2OS 24 569 ADCCM +0.24107970081124444 3.6650336936702597e-08 BR00117025 ixabepilone final compound J21 U2OS 24 298 ADCCM +0.2520703933747412 3.741336939237123e-08 BR00117024 buparlisib final compound D11 U2OS 24 276 ADCCM +0.27114274721046555 6.937544553288325e-08 BR00117026 buparlisib final compound L12 U2OS 24 226 ADCCM +0.24457880504107352 7.29551414600058e-08 BR00117025 BI-2536 final compound E21 U2OS 24 278 ADCCM +0.2088637562737591 7.971123285831606e-08 BR00116995 AVL-292 final compound A24 U2OS 24 383 ADCCM +0.2209073658789029 9.573184677272748e-08 BR00116995 BI-2536 final compound E21 U2OS 24 340 ADCCM +0.16676904176904178 1.1497367710745985e-07 BR00117026 AZ191 final compound I18 U2OS 24 592 ADCCM +0.23077915376676986 1.1800025698901024e-07 BR00116995 buparlisib final compound D11 U2OS 24 304 ADCCM +0.15364922128666555 2.0387772215337577e-07 BR00117025 BMS-536924 final compound B15 U2OS 24 673 ADCCM +0.1692906937128181 2.0521865476944814e-07 BR00117026 WH-4-023 final compound A18 U2OS 24 552 ADCCM +0.22498743086978382 2.3450392413266384e-07 BR00117024 ixabepilone final compound J21 U2OS 24 306 ADCCM +0.178 2.4610680377802874e-07 BR00117024 fludarabine-phosphate final compound N12 U2OS 24 500 ADCCM +0.18155710647929832 3.6083988197470774e-07 BR00117025 WH-4-023 final compound A18 U2OS 24 460 ADCCM +0.15280277084421742 4.6952600527614085e-07 BR00117025 AZ191 final compound I18 U2OS 24 644 ADCCM +0.15360164221583933 7.883574258492982e-07 BR00116995 WH-4-023 final compound A18 U2OS 24 617 ADCCM +0.12493682529705062 8.122400585654327e-07 BR00117024 AC-710 final compound I03 U2OS 24 931 ADCCM +0.17634408602150536 9.884009535328844e-07 BR00117024 UNC1999 final compound H19 U2OS 24 465 ADCCM +0.19783609576427255 1.080616724366603e-06 BR00117024 BI-2536 final compound I14 U2OS 24 362 ADCCM +0.22944297082228116 1.4296919059328025e-06 BR00116995 ixabepilone final compound J21 U2OS 24 261 ADCCM +0.19529599549316934 1.7071611304557217e-06 BR00117024 7-hydroxystaurosporine final compound L04 U2OS 24 358 ADCCM +0.11632453567937438 1.8992500738461233e-06 BR00117025 polydatin final compound K08 U2OS 24 1023 ADCCM +0.19068742655699178 2.207487304584184e-06 BR00117026 buparlisib final compound D11 U2OS 24 368 ADCCM +0.12359148192391028 2.5326924803908703e-06 BR00117025 SB-203580 final compound L08 U2OS 24 883 ADCCM +0.1627450980392157 2.5959650755391477e-06 BR00117026 ganetespib final compound M10 U2OS 24 510 ADCCM +0.12693665666703702 3.854634417939065e-06 BR00117026 PP-2 final compound J10 U2OS 24 806 ADCCM +0.1808002388772768 4.230234776979448e-06 BR00117025 PP-121 final compound B16 U2OS 24 391 ADCCM +0.23837997289324722 4.2874090548756456e-06 BR00117025 NSC-632839 final compound M16 U2OS 24 222 ADCCM +0.12946338529691115 6.756040713135876e-06 BR00117024 ingenol-mebutate final compound M11 U2OS 24 738 ADCCM +0.21268282093723714 7.050802604777384e-06 BR00117024 KG-5 final compound C13 U2OS 24 274 ADCCM +0.20469798657718122 7.062241835782468e-06 BR00117026 BI-2536 final compound E21 U2OS 24 298 ADCCM +0.14104244746586891 1.2521530736026422e-05 BR00116995 BMS-536924 final compound B15 U2OS 24 597 ADCCM 0.5878450139317531 3.1668322307812667e-79 BR00116995 AMG900 final compound N09 U2OS 24 491 Anaphase 0.5696465696465697 2.2589031793964085e-72 BR00117024 danusertib final compound E05 U2OS 24 481 Anaphase 0.5383147512864493 1.0494470683815775e-70 BR00117025 AMG900 final compound N09 U2OS 24 528 Anaphase @@ -319,6 +3109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5644616612321043 1.7775206492035447e-64 BR00117024 AMG900 final compound N09 U2OS 24 433 Anaphase 0.5249239381769503 2.9946690685359226e-63 BR00116995 PF-431396 final compound L20 U2OS 24 498 Anaphase 0.5294150494403065 3.16703035309977e-62 BR00117024 danusertib final compound N18 U2OS 24 482 Anaphase +0.5498117242341127 1.6666102889455285e-61 BR00116995 danusertib final compound N18 U2OS 24 439 Anaphase +0.5146459820979583 2.1973383371954794e-59 BR00117026 danusertib final compound E05 U2OS 24 488 Anaphase +0.4993849118126575 2.851057034608443e-59 BR00117024 PF-431396 final compound L20 U2OS 24 519 Anaphase +0.5606733167082294 8.194090173603833e-59 BR00117024 GSK1070916 final compound C04 U2OS 24 401 Anaphase +0.46235836627140975 1.2439125778735792e-53 BR00117025 PF-431396 final compound L20 U2OS 24 550 Anaphase +0.48248082683255983 2.0554046917875312e-52 BR00117026 AMG900 final compound N09 U2OS 24 492 Anaphase +0.5404147870740772 6.738284162574393e-51 BR00117024 epothilone-b final compound F07 U2OS 24 372 Anaphase +0.44806452862844376 9.8884544813903e-51 BR00117026 PF-431396 final compound L20 U2OS 24 556 Anaphase +0.48413287503854013 3.2148012401997066e-45 BR00117025 GSK1070916 final compound C04 U2OS 24 419 Anaphase +0.5315612629635013 1.1468747089841357e-44 BR00116995 epothilone-b final compound F07 U2OS 24 341 Anaphase +0.4847919655667145 2.9575787661068087e-44 BR00117026 epothilone-b final compound F07 U2OS 24 410 Anaphase +0.4860210855134713 1.4905370370291352e-42 BR00117025 epothilone-b final compound F07 U2OS 24 390 Anaphase +0.5165912518853696 3.796868744432882e-38 BR00117024 ixabepilone final compound J21 U2OS 24 306 Anaphase +0.5227835864842942 7.050774693697014e-38 BR00117026 puromycin final compound C22 U2OS 24 299 Anaphase +0.5063837479944863 1.7263219117117498e-35 BR00117025 ixabepilone final compound J21 U2OS 24 298 Anaphase +0.4044260337363786 1.6273374444932868e-34 BR00117026 UNC2025 final compound N06 U2OS 24 464 Anaphase +0.35301360140214666 1.3367500617994585e-29 BR00117026 fludarabine-phosphate final compound N12 U2OS 24 527 Anaphase +0.505480398933544 1.8907422915919638e-29 BR00117025 AZD7762 final compound K11 U2OS 24 247 Anaphase +0.4772867035640758 7.095452152918693e-29 BR00117025 puromycin final compound C22 U2OS 24 274 Anaphase +0.5096549258001073 1.4895132070488351e-28 BR00117025 ponatinib final compound C20 U2OS 24 235 Anaphase +0.352 6.905390544320902e-28 BR00117024 fludarabine-phosphate final compound N12 U2OS 24 500 Anaphase +0.4355701754385965 2.688389850821624e-26 BR00117025 NSC-663284 final compound G06 U2OS 24 304 Anaphase +0.46654877689360447 2.8496473312404146e-26 BR00116995 ixabepilone final compound J21 U2OS 24 261 Anaphase +0.36815714892201074 7.989381898557076e-26 BR00117025 UNC2025 final compound N06 U2OS 24 418 Anaphase +0.5434182080230603 3.084670873725842e-25 BR00116995 ponatinib final compound C20 U2OS 24 181 Anaphase +0.4396415861718353 8.019863965654816e-25 BR00117026 ixabepilone final compound J21 U2OS 24 280 Anaphase +0.5670731707317073 1.1526451151184046e-24 BR00117024 ponatinib final compound C20 U2OS 24 164 Anaphase +0.4811222320980021 2.355555858788488e-24 BR00117025 SU3327 final compound I20 U2OS 24 226 Anaphase +0.41251696419250444 2.856828807395683e-24 BR00116995 UNC2025 final compound N06 U2OS 24 310 Anaphase +0.5181737588652482 6.835356656605574e-24 BR00117025 ryuvidine final compound A14 U2OS 24 192 Anaphase +0.4279495686794957 5.0990947607518907e-23 BR00117026 AZD7762 final compound K11 U2OS 24 275 Anaphase +0.4959059255669209 7.584523261917528e-23 BR00117026 ponatinib final compound C20 U2OS 24 199 Anaphase +0.3714620821630297 1.3401097449313676e-22 BR00117025 UNC1999 final compound H19 U2OS 24 362 Anaphase +0.33342066811104953 1.560715442472718e-22 BR00116995 fludarabine-phosphate final compound N12 U2OS 24 445 Anaphase +0.423652855302705 1.753708159173216e-22 BR00116995 puromycin final compound C22 U2OS 24 272 Anaphase +0.4593222869084938 1.7887973212067248e-22 BR00117024 ryuvidine final compound A14 U2OS 24 231 Anaphase +0.30667280610874487 8.25123451240002e-22 BR00117025 fludarabine-phosphate final compound N12 U2OS 24 510 Anaphase +0.35816618911174786 2.8084692855934596e-20 BR00117026 UNC1999 final compound H19 U2OS 24 349 Anaphase +0.4301737644210226 3.5937627119825253e-20 BR00117025 AZD7762 final compound I05 U2OS 24 236 Anaphase +0.398814207798551 8.280419676620529e-20 BR00117024 KG-5 final compound C13 U2OS 24 274 Anaphase +0.22580671544945966 1.4376955868788077e-19 BR00117025 AC-710 final compound I03 U2OS 24 856 Anaphase +0.42463421700709836 1.8175600710373523e-19 BR00117024 AZD7762 final compound K11 U2OS 24 234 Anaphase +0.3614178360555172 3.170084727612256e-19 BR00117024 UNC2025 final compound N06 U2OS 24 322 Anaphase +0.38045384218669415 1.5612659871147105e-18 BR00117025 KG-5 final compound C13 U2OS 24 277 Anaphase +0.2771264318989564 2.0222379717724247e-18 BR00117024 JTE-607 final compound C14 U2OS 24 532 Anaphase +0.3651315789473684 2.0733962547876034e-18 BR00117026 NSC-663284 final compound G06 U2OS 24 304 Anaphase +0.43564356435643564 1.3366780586369253e-17 BR00117026 AZD7762 final compound I05 U2OS 24 202 Anaphase +0.36929042462276307 1.4120714521051837e-17 BR00116995 SU3327 final compound I20 U2OS 24 281 Anaphase +0.34025195194610486 5.640417321891642e-17 BR00117026 KG-5 final compound C13 U2OS 24 319 Anaphase +0.3516630994388847 1.0071666771416726e-16 BR00117025 delanzomib final compound L11 U2OS 24 295 Anaphase +0.35909995407928974 1.4102224728735516e-16 BR00117024 delanzomib final compound L11 U2OS 24 282 Anaphase +0.24789713182570325 1.8760098196657953e-16 BR00117025 azeliragon final compound C08 U2OS 24 588 Anaphase +0.27956989247311825 2.100535792117838e-16 BR00117024 UNC1999 final compound H19 U2OS 24 465 Anaphase +0.3549978148217519 2.165599037050319e-16 BR00117024 NSC-663284 final compound G06 U2OS 24 285 Anaphase +0.23623929127725857 3.2403733528739e-16 BR00117025 KU-60019 final compound I07 U2OS 24 642 Anaphase +0.42 3.432078828289855e-16 BR00117024 AZD7762 final compound I05 U2OS 24 200 Anaphase +0.20240355772776558 8.126279620851206e-16 BR00117026 AC-710 final compound I03 U2OS 24 853 Anaphase +0.334587485594197 2.4383501883110053e-15 BR00116995 briciclib final compound H01 U2OS 24 297 Anaphase +0.22767712328505735 3.776947029608678e-15 BR00117026 azeliragon final compound C08 U2OS 24 648 Anaphase +0.29044409199048377 5.7450985146412565e-15 BR00117024 RGB-286638 final compound K21 U2OS 24 388 Anaphase +0.336105476673428 6.081928410327164e-15 BR00116995 NSC-632839 final compound M16 U2OS 24 289 Anaphase +0.21801689083515796 6.420569935616945e-15 BR00117026 JTE-607 final compound C14 U2OS 24 695 Anaphase +0.197391114139808 6.5002169466514924e-15 BR00116995 BAN-ORL-24 final compound A15 U2OS 24 846 Anaphase +0.2989942495103891 1.1675578439713593e-14 BR00117024 PHA-793887 final compound I06 U2OS 24 359 Anaphase +0.18551661652984092 1.783580181768982e-14 BR00117024 AC-710 final compound I03 U2OS 24 931 Anaphase +0.4134099616858238 4.283174911434298e-14 BR00117026 ryuvidine final compound A14 U2OS 24 174 Anaphase +0.22818791946308725 5.193532217467304e-14 BR00117024 azeliragon final compound C08 U2OS 24 596 Anaphase +0.2176030703199959 8.07325128553547e-14 BR00117025 NVP-ADW742 final compound D16 U2OS 24 641 Anaphase +0.35223203205332765 9.669462059044476e-14 BR00116995 oxibendazole final compound M19 U2OS 24 238 Anaphase +0.3600813202583114 2.014937710897678e-13 BR00117025 NSC-632839 final compound M16 U2OS 24 222 Anaphase +0.4962121212121212 2.185403845797506e-13 BR00117025 LDN-212854 final compound K01 U2OS 24 110 Anaphase +0.22522430857459994 4.0870717055776735e-13 BR00116995 UNC1999 final compound H19 U2OS 24 569 Anaphase +0.34997040106556165 4.4920575574890393e-13 BR00117024 oxibendazole final compound M19 U2OS 24 232 Anaphase +0.35782828282828283 6.233061203207277e-13 BR00117024 CYT-997 final compound E06 U2OS 24 220 Anaphase +0.20296137630898953 7.111945559037667e-13 BR00117024 KU-60019 final compound I07 U2OS 24 688 Anaphase +0.27070716554778335 4.190035970005232e-12 BR00117024 7-hydroxystaurosporine final compound L04 U2OS 24 358 Anaphase +0.3131741821396994 6.618517222923168e-12 BR00117026 briciclib final compound H01 U2OS 24 261 Anaphase +0.3071381263263182 7.446685512879485e-12 BR00116995 delanzomib final compound L11 U2OS 24 271 Anaphase +0.28161844271936015 7.51426292199591e-12 BR00117026 PHA-793887 final compound E13 U2OS 24 327 Anaphase +0.27613412228796846 7.537082467436447e-12 BR00117025 RGB-286638 final compound K21 U2OS 24 336 Anaphase +0.2672413793103448 2.46089836906085e-11 BR00117026 RGB-286638 final compound K21 U2OS 24 348 Anaphase +0.26282400284057283 2.5687513751269892e-11 BR00117026 7-hydroxystaurosporine final compound L04 U2OS 24 355 Anaphase +0.19582846573208723 3.0442441897105434e-11 BR00117026 KU-60019 final compound I07 U2OS 24 642 Anaphase +0.277735225348706 3.16142475275676e-11 BR00116995 7-hydroxystaurosporine final compound L04 U2OS 24 316 Anaphase +0.277398676592225 4.1169083619474144e-11 BR00116995 BI-2536 final compound I14 U2OS 24 312 Anaphase +0.23667778633136602 4.5675737011928654e-11 BR00116995 RGB-286638 final compound K21 U2OS 24 432 Anaphase +0.2998570611778159 6.053661863466485e-11 BR00117024 SU3327 final compound I20 U2OS 24 265 Anaphase +0.22367978770455552 7.2738943239914e-11 BR00117025 BAX-channel-blocker final compound I19 U2OS 24 475 Anaphase +0.2629288965079144 7.937914011095296e-11 BR00117024 PHA-793887 final compound E13 U2OS 24 341 Anaphase +0.16646989374262103 1.1631803383131071e-10 BR00117025 RKI-1447 final compound J04 U2OS 24 847 Anaphase 0.5412577881619938 1.6644496357951416e-86 BR00117025 KU-60019 final compound I07 U2OS 24 642 Apoptosis 0.5042499660002719 8.388271614369392e-80 BR00117024 KU-60019 final compound I07 U2OS 24 688 Apoptosis 0.4868380062305296 1.3632811814525359e-69 BR00117026 KU-60019 final compound I07 U2OS 24 642 Apoptosis @@ -329,6 +3209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.314736668317649 4.010695786131455e-30 BR00117025 BMS-536924 final compound B15 U2OS 24 673 Apoptosis 0.35586714370554917 4.2431272251118374e-30 BR00117026 fludarabine-phosphate final compound N12 U2OS 24 527 Apoptosis 0.29838709677419356 1.2879263113208379e-29 BR00117025 PP-2 final compound J10 U2OS 24 744 Apoptosis +0.3271205525957547 9.939923309723717e-29 BR00116995 BMS-536924 final compound B15 U2OS 24 597 Apoptosis +0.3216064165969929 1.009815042686032e-27 BR00117026 BMS-536924 final compound B15 U2OS 24 593 Apoptosis +0.3138145647159244 2.349914415313435e-27 BR00116995 WH-4-023 final compound A18 U2OS 24 617 Apoptosis +0.43070224945577684 9.738302295932744e-27 BR00116995 7-hydroxystaurosporine final compound L04 U2OS 24 316 Apoptosis +0.26208744521003174 5.868129202779821e-26 BR00116995 BAN-ORL-24 final compound A15 U2OS 24 846 Apoptosis +0.43129368104090043 1.1287101326303814e-25 BR00117026 puromycin final compound C22 U2OS 24 299 Apoptosis +0.24195223260643822 3.8563357527308545e-25 BR00117026 polydatin final compound K08 U2OS 24 963 Apoptosis +0.3827119580226457 6.916140654518805e-24 BR00117026 7-hydroxystaurosporine final compound L04 U2OS 24 355 Apoptosis +0.32209048002762747 7.53390840805029e-24 BR00117025 fludarabine-phosphate final compound N12 U2OS 24 510 Apoptosis +0.25454921422663357 2.28697584037082e-23 BR00117026 PP-2 final compound J10 U2OS 24 806 Apoptosis +0.46111210441623457 2.9932156074202094e-23 BR00117025 ponatinib final compound C20 U2OS 24 235 Apoptosis +0.305443044998058 1.1908940800091206e-22 BR00116995 PP-121 final compound B16 U2OS 24 538 Apoptosis +0.3297180043383948 1.4054470229131526e-22 BR00117026 AVL-292 final compound A24 U2OS 24 461 Apoptosis +0.3390575471389824 2.483701643559312e-22 BR00117025 AVL-292 final compound A24 U2OS 24 431 Apoptosis +0.2978516392798176 3.0988103006863367e-22 BR00117026 WH-4-023 final compound A18 U2OS 24 552 Apoptosis +0.36754925433860697 6.631423894631914e-22 BR00117024 7-hydroxystaurosporine final compound L04 U2OS 24 358 Apoptosis +0.41835779791984173 7.244131309422421e-22 BR00117025 puromycin final compound C22 U2OS 24 274 Apoptosis +0.3433860853986265 3.999434023793816e-21 BR00117025 PP-121 final compound B16 U2OS 24 391 Apoptosis +0.42763569336098217 1.2049412768019534e-20 BR00117025 AZD7762 final compound K11 U2OS 24 247 Apoptosis +0.2534506781278661 3.823812293748666e-20 BR00117024 PP-2 final compound J10 U2OS 24 697 Apoptosis +0.37837719298245615 7.418799972044891e-20 BR00117025 NSC-663284 final compound G06 U2OS 24 304 Apoptosis +0.2862595419847328 2.558718297168688e-19 BR00117024 AVL-292 final compound A24 U2OS 24 524 Apoptosis +0.2987597849665189 9.371802863187974e-19 BR00117025 WH-4-023 final compound A18 U2OS 24 460 Apoptosis +0.38017252820172526 4.112982706140646e-18 BR00117026 AZD7762 final compound K11 U2OS 24 275 Apoptosis +0.32396681387834575 5.1055441043369955e-18 BR00117026 PP-121 final compound B16 U2OS 24 374 Apoptosis +0.22096473228214175 6.74289849596115e-18 BR00117025 arcyriaflavin-a final compound B04 U2OS 24 817 Apoptosis +0.31454023999242414 2.311444073503432e-17 BR00116995 AVL-292 final compound A24 U2OS 24 383 Apoptosis +0.24019634892169034 3.975892207170578e-17 BR00116995 PP-2 final compound J10 U2OS 24 660 Apoptosis +0.3268262122541035 6.17907162663237e-17 BR00117025 7-hydroxystaurosporine final compound L04 U2OS 24 345 Apoptosis +0.2348181365221724 9.50866465232275e-17 BR00117026 PP-1 final compound A22 U2OS 24 669 Apoptosis +0.24433656957928804 1.3421655964251826e-16 BR00117026 BAN-ORL-24 final compound A15 U2OS 24 618 Apoptosis +0.24707701489298212 5.9613815712033485e-16 BR00117025 BAN-ORL-24 final compound A15 U2OS 24 579 Apoptosis +0.4324405476819601 6.274991272784535e-16 BR00116995 ponatinib final compound C20 U2OS 24 181 Apoptosis +0.2607843137254902 1.195497454462335e-15 BR00117026 ganetespib final compound M10 U2OS 24 510 Apoptosis +0.3123209169054441 1.9424762897782266e-15 BR00117026 UNC1999 final compound H19 U2OS 24 349 Apoptosis +0.2468194205856141 2.5449996397726434e-15 BR00117026 PF-431396 final compound L20 U2OS 24 556 Apoptosis +0.23723561902195878 1.0993120921738013e-14 BR00117024 BMS-536924 final compound B15 U2OS 24 571 Apoptosis +0.3256578947368421 1.1614742921767238e-14 BR00117026 NSC-663284 final compound G06 U2OS 24 304 Apoptosis +0.24366353737450971 2.3349265473801768e-14 BR00117024 JTE-607 final compound C14 U2OS 24 532 Apoptosis +0.29365103861230285 3.469678534187665e-14 BR00117025 UNC1999 final compound H19 U2OS 24 362 Apoptosis +0.30637438276223256 3.747452402217466e-14 BR00117024 TG-101348 final compound M20 U2OS 24 328 Apoptosis +0.31997375014914686 9.501421816590748e-14 BR00116995 NSC-632839 final compound M16 U2OS 24 289 Apoptosis +0.3873172971456266 9.638357230273333e-14 BR00117026 ponatinib final compound C20 U2OS 24 199 Apoptosis +0.3546284224250326 1.0006766178187978e-13 BR00117024 AZD7762 final compound K11 U2OS 24 234 Apoptosis +0.2642669629532804 1.1642891574382638e-13 BR00117025 ganetespib final compound I17 U2OS 24 431 Apoptosis +0.39361702127659576 1.1913604292248127e-13 BR00117025 ryuvidine final compound A14 U2OS 24 192 Apoptosis +0.25669642857142855 2.242666943722512e-13 BR00117025 ganetespib final compound M10 U2OS 24 448 Apoptosis +0.32339523400601117 3.132897373502488e-13 BR00116995 puromycin final compound C22 U2OS 24 272 Apoptosis +0.37623762376237624 4.026483410900558e-13 BR00117026 AZD7762 final compound I05 U2OS 24 202 Apoptosis +0.35362353503946425 5.309042077260477e-13 BR00117025 NSC-632839 final compound M16 U2OS 24 222 Apoptosis +0.3164581180882409 6.668194003378594e-13 BR00116995 SU3327 final compound I20 U2OS 24 281 Apoptosis +0.21569888416335117 1.2959903381511333e-12 BR00116995 ganetespib final compound I17 U2OS 24 592 Apoptosis +0.3119802030715853 1.3699961007686194e-12 BR00117025 TG-101348 final compound M20 U2OS 24 278 Apoptosis +0.2558927150812592 1.6467120828973826e-12 BR00117026 ganetespib final compound I17 U2OS 24 419 Apoptosis +0.3347101552485401 2.3399817812320087e-12 BR00117025 AZD7762 final compound I05 U2OS 24 236 Apoptosis +0.259778233462444 2.861230357067018e-12 BR00117024 PP-121 final compound B16 U2OS 24 399 Apoptosis +0.20458546041372172 3.412646674813719e-12 BR00117025 NVP-ADW742 final compound D16 U2OS 24 641 Apoptosis +0.23092369477911648 4.730920017730799e-12 BR00117025 danusertib final compound E05 U2OS 24 498 Apoptosis +0.3155747854843174 5.083971027245161e-12 BR00117026 NSC-632839 final compound M16 U2OS 24 263 Apoptosis +0.23284823284823286 7.630045179668436e-12 BR00117024 danusertib final compound E05 U2OS 24 481 Apoptosis +0.3217687074829932 1.2407282802628653e-11 BR00117024 NSC-632839 final compound M16 U2OS 24 240 Apoptosis +0.18116674420718828 3.209598035276659e-11 BR00117026 arcyriaflavin-a final compound B04 U2OS 24 751 Apoptosis +0.19916358330293396 3.466049414083747e-11 BR00117026 NVP-ADW742 final compound D16 U2OS 24 620 Apoptosis +0.2705947357846092 1.3266290303060657e-10 BR00117026 homoharringtonine final compound N15 U2OS 24 315 Apoptosis +0.18900862480203026 1.5019306324129163e-10 BR00117026 azeliragon final compound C08 U2OS 24 648 Apoptosis +0.2727272727272727 1.7431781371585383e-10 BR00116995 TG-101348 final compound M20 U2OS 24 308 Apoptosis +0.1642345244863723 2.088687284584559e-10 BR00117026 SB-203580 final compound L08 U2OS 24 843 Apoptosis +0.1793973516838703 3.19607266617144e-10 BR00117026 JTE-607 final compound C14 U2OS 24 695 Apoptosis +0.30547469771607705 3.7512328057920833e-10 BR00117024 ryuvidine final compound A14 U2OS 24 231 Apoptosis +0.4303030303030303 4.437539574408552e-10 BR00117025 LDN-212854 final compound K01 U2OS 24 110 Apoptosis +0.2764188050196666 4.717112571486745e-10 BR00117024 NSC-663284 final compound G06 U2OS 24 285 Apoptosis +0.2753332093484595 4.741436278140939e-10 BR00117026 TG-101348 final compound M20 U2OS 24 283 Apoptosis +0.19649122807017544 4.893029684087576e-10 BR00116995 NVP-ADW742 final compound D16 U2OS 24 570 Apoptosis +0.22150424330704188 5.670984617984929e-10 BR00116995 danusertib final compound N18 U2OS 24 439 Apoptosis +0.2203989703989704 6.405599524749905e-10 BR00117026 NVP-HSP990 final compound E23 U2OS 24 441 Apoptosis +0.27588142252155723 6.497235950276557e-10 BR00117024 delanzomib final compound L11 U2OS 24 282 Apoptosis +0.3448275862068966 7.291923407032823e-10 BR00117026 ryuvidine final compound A14 U2OS 24 174 Apoptosis +0.3962962962962963 7.85229131031187e-10 BR00117026 LDN-212854 final compound K01 U2OS 24 135 Apoptosis +0.2490764851934839 9.041235361872319e-10 BR00117024 anisomycin final compound N03 U2OS 24 343 Apoptosis +0.20553359683794467 9.133697085212638e-10 BR00117026 danusertib final compound N18 U2OS 24 506 Apoptosis +0.19039451114922812 1.1870858931008732e-09 BR00117024 PP-1 final compound A22 U2OS 24 583 Apoptosis +0.3069023569023569 1.3978028788326609e-09 BR00117024 CYT-997 final compound E06 U2OS 24 220 Apoptosis +0.2077781500476792 1.4217044028692632e-09 BR00117024 danusertib final compound N18 U2OS 24 482 Apoptosis +0.14898236092265943 1.5172177811535202e-09 BR00117024 lonafarnib final compound J06 U2OS 24 935 Apoptosis +0.2985276500367121 1.7210427386880203e-09 BR00117025 SU3327 final compound I20 U2OS 24 226 Apoptosis +0.22332615973218556 1.7804716444564525e-09 BR00117026 epothilone-b final compound F07 U2OS 24 410 Apoptosis +0.16974921348673253 2.0046979645135622e-09 BR00117024 arcyriaflavin-a final compound B04 U2OS 24 707 Apoptosis +0.2045990566037736 2.818323409496086e-09 BR00117024 ganetespib final compound M10 U2OS 24 480 Apoptosis +0.15301284062326284 3.7039600729104377e-09 BR00117026 AC-710 final compound I03 U2OS 24 853 Apoptosis +0.16333266874903082 4.644567945376658e-09 BR00117025 lonafarnib final compound F22 U2OS 24 734 Apoptosis 0.7499861109567884 6.915404673297038e-83 BR00117026 puromycin final compound C22 U2OS 24 299 Binuclear 0.7730417381360778 3.016563520047586e-78 BR00117024 SU3327 final compound I20 U2OS 24 265 Binuclear 0.7586695542899923 1.339745940820695e-77 BR00117025 puromycin final compound C22 U2OS 24 274 Binuclear @@ -339,6 +3309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.7362740837317109 1.6090340722957024e-62 BR00117024 AZD7762 final compound K11 U2OS 24 234 Binuclear 0.6786570743405276 6.07440756655815e-62 BR00117024 delanzomib final compound L11 U2OS 24 282 Binuclear 0.7370638018317425 5.516898267974491e-61 BR00117025 SU3327 final compound I20 U2OS 24 226 Binuclear +0.4556804906542056 1.007525589959461e-60 BR00117026 KU-60019 final compound I07 U2OS 24 642 Binuclear +0.7218344965104686 1.4435946608037992e-60 BR00117025 AZD7762 final compound I05 U2OS 24 236 Binuclear +0.6740285530270502 1.7165298336190403e-59 BR00116995 puromycin final compound C22 U2OS 24 272 Binuclear +0.6721035169210352 2.479497690323553e-59 BR00117026 AZD7762 final compound K11 U2OS 24 275 Binuclear +0.6997136368124814 3.300274122231445e-58 BR00117025 AZD7762 final compound K11 U2OS 24 247 Binuclear +0.765 8.923619080953326e-58 BR00117024 AZD7762 final compound I05 U2OS 24 200 Binuclear +0.708367602360093 1.1932498028426405e-57 BR00117025 ponatinib final compound C20 U2OS 24 235 Binuclear +0.6397061375600162 2.152493832849755e-57 BR00117025 delanzomib final compound L11 U2OS 24 295 Binuclear +0.7376237623762376 1.1058507962300044e-53 BR00117026 AZD7762 final compound I05 U2OS 24 202 Binuclear +0.5992105263157895 6.576945881797343e-51 BR00117025 NSC-663284 final compound G06 U2OS 24 304 Binuclear +0.5888157894736842 3.3133834863618923e-49 BR00117026 NSC-663284 final compound G06 U2OS 24 304 Binuclear +0.7070632349565085 4.6415249889111374e-48 BR00117026 ponatinib final compound C20 U2OS 24 199 Binuclear +0.5017814442850311 1.4975309660420352e-47 BR00117026 epothilone-b final compound F07 U2OS 24 410 Binuclear +0.6630575307045895 6.498411427128602e-47 BR00117024 puromycin final compound C22 U2OS 24 224 Binuclear +0.6500410509031199 1.4843743012809442e-46 BR00117024 ryuvidine final compound A14 U2OS 24 231 Binuclear +0.7439024390243902 1.7666308246700626e-44 BR00117024 ponatinib final compound C20 U2OS 24 164 Binuclear +0.5134578971253306 9.42701911276828e-44 BR00117024 7-hydroxystaurosporine final compound L04 U2OS 24 358 Binuclear +0.5862491277538059 6.5924263787973616e-43 BR00117026 delanzomib final compound L11 U2OS 24 267 Binuclear +0.6939406677876532 6.905784269685713e-43 BR00116995 ponatinib final compound C20 U2OS 24 181 Binuclear +0.5365234217528018 4.472235283476622e-42 BR00116995 7-hydroxystaurosporine final compound L04 U2OS 24 316 Binuclear +0.4712174085737793 2.788389908695706e-38 BR00117024 epothilone-b final compound F07 U2OS 24 372 Binuclear +0.5233146402577258 9.788854906593341e-37 BR00116995 NSC-632839 final compound M16 U2OS 24 289 Binuclear +0.44891318495379406 4.311666435763421e-36 BR00117025 epothilone-b final compound F07 U2OS 24 390 Binuclear +0.558843537414966 2.0185620318322662e-35 BR00117024 NSC-632839 final compound M16 U2OS 24 240 Binuclear +0.6215647163120568 5.44270437592804e-35 BR00117025 ryuvidine final compound A14 U2OS 24 192 Binuclear +0.46030693967727937 1.8259275500641974e-34 BR00117026 7-hydroxystaurosporine final compound L04 U2OS 24 355 Binuclear +0.6270114942528736 3.960087381378699e-33 BR00117026 ryuvidine final compound A14 U2OS 24 174 Binuclear +0.4973091090716114 2.7544854559976405e-32 BR00117024 NSC-663284 final compound G06 U2OS 24 285 Binuclear +0.5066163848451671 3.151900553559579e-32 BR00116995 delanzomib final compound L11 U2OS 24 271 Binuclear +0.6994301994301995 9.270909296638636e-32 BR00117026 LDN-212854 final compound K01 U2OS 24 135 Binuclear +0.7227272727272728 1.5321254491847323e-29 BR00117025 LDN-212854 final compound K01 U2OS 24 110 Binuclear +0.6812621124031008 3.2916542446878386e-29 BR00117024 LDN-212854 final compound K01 U2OS 24 129 Binuclear +0.2585669781931464 1.08288176645687e-28 BR00117026 polydatin final compound K08 U2OS 24 963 Binuclear +0.24873845060412225 8.476906718378425e-28 BR00117024 polydatin final compound K08 U2OS 24 1005 Binuclear +0.46601984179013156 2.2221341603330242e-26 BR00117026 NSC-632839 final compound M16 U2OS 24 263 Binuclear +0.5002790401020489 4.545101014536956e-26 BR00117025 NSC-632839 final compound M16 U2OS 24 222 Binuclear +0.23460410557184752 4.2753737289034e-25 BR00117025 polydatin final compound K08 U2OS 24 1023 Binuclear +0.4228727957541517 2.0290621521618082e-24 BR00117025 thiostrepton final compound B02 U2OS 24 297 Binuclear +0.3823431341535357 9.478998861874827e-23 BR00116995 epothilone-b final compound F07 U2OS 24 341 Binuclear +0.37822349570200575 1.268009280869142e-22 BR00117026 UNC1999 final compound H19 U2OS 24 349 Binuclear +0.391304347826087 2.1954284964507083e-22 BR00117026 thiostrepton final compound B02 U2OS 24 322 Binuclear +0.40675544670646463 3.19268238632071e-21 BR00117025 TG-101348 final compound M20 U2OS 24 278 Binuclear +0.3587919380227785 3.611117333074225e-21 BR00117025 UNC1999 final compound H19 U2OS 24 362 Binuclear +0.29164690382081687 3.883052533754998e-21 BR00117025 PF-431396 final compound L20 U2OS 24 550 Binuclear +0.2899009338310321 4.675484706461424e-21 BR00117026 PF-431396 final compound L20 U2OS 24 556 Binuclear +0.2881679389312977 1.4177194713201324e-19 BR00117024 AVL-292 final compound A24 U2OS 24 524 Binuclear +0.391841682257767 1.8689261023700459e-19 BR00117024 thiostrepton final compound B02 U2OS 24 277 Binuclear +0.22225587441003508 8.130702045351452e-19 BR00116995 BAN-ORL-24 final compound A15 U2OS 24 846 Binuclear +0.34339890573445264 1.5087025297079696e-18 BR00117025 7-hydroxystaurosporine final compound L04 U2OS 24 345 Binuclear +0.3332412523020258 2.3412225973070867e-18 BR00117024 BI-2536 final compound I14 U2OS 24 362 Binuclear +0.2950108459869848 4.307966468869601e-18 BR00117026 AVL-292 final compound A24 U2OS 24 461 Binuclear +0.26427404187093395 5.359767551692899e-18 BR00116995 UNC1999 final compound H19 U2OS 24 569 Binuclear +0.25 9.219170223755544e-17 BR00117024 azeliragon final compound C08 U2OS 24 596 Binuclear +0.2641580903373356 1.0758591391879265e-16 BR00117025 AMG900 final compound N09 U2OS 24 528 Binuclear +0.2905460605862554 1.8369316323685353e-16 BR00117025 AVL-292 final compound A24 U2OS 24 431 Binuclear +0.23255517032634418 1.917207659744356e-16 BR00117025 BMS-536924 final compound B15 U2OS 24 673 Binuclear +0.23689259852338912 4.34456707496218e-15 BR00117026 BMS-536924 final compound B15 U2OS 24 593 Binuclear +0.31891474836655564 6.436150514819705e-15 BR00117024 BI-2536 final compound E21 U2OS 24 317 Binuclear +0.28680718083307405 2.0475319516105386e-14 BR00116995 AVL-292 final compound A24 U2OS 24 383 Binuclear +0.2834525555973879 2.2706054174003208e-14 BR00117025 PP-121 final compound B16 U2OS 24 391 Binuclear +0.22812221643333724 4.462490531580337e-14 BR00116995 BMS-536924 final compound B15 U2OS 24 597 Binuclear +0.24754776682487525 6.873731063238316e-14 BR00116995 PF-431396 final compound L20 U2OS 24 498 Binuclear +0.25591397849462366 8.74059220011145e-14 BR00117024 UNC1999 final compound H19 U2OS 24 465 Binuclear +0.26314732508548205 9.164146859970177e-14 BR00117024 AMG900 final compound N09 U2OS 24 433 Binuclear +0.30018330091276374 1.35796329363237e-13 BR00117024 TG-101348 final compound M20 U2OS 24 328 Binuclear +0.3236134496657993 1.7301464334538922e-13 BR00117025 BI-2536 final compound E21 U2OS 24 278 Binuclear +0.35205707663334784 2.0842907252460716e-13 BR00117024 colchicine final compound K17 U2OS 24 234 Binuclear +0.30844155844155846 2.438742326932105e-13 BR00116995 TG-101348 final compound M20 U2OS 24 308 Binuclear +0.2809048178613396 2.605232327536084e-13 BR00117026 buparlisib final compound D11 U2OS 24 368 Binuclear +0.1989247311827957 2.742208983923584e-13 BR00117025 PP-2 final compound J10 U2OS 24 744 Binuclear +0.28968038082284936 3.2838213235519683e-13 BR00117025 BI-2536 final compound I14 U2OS 24 340 Binuclear +0.31955712026123784 3.5079590913488416e-13 BR00117025 oxibendazole final compound M19 U2OS 24 278 Binuclear +0.28891668104191826 5.792000472992034e-13 BR00116995 BI-2536 final compound E21 U2OS 24 340 Binuclear +0.18133734018019804 8.639597805744261e-13 BR00117026 AC-710 final compound I03 U2OS 24 853 Binuclear +0.3593996840442338 9.546464744510935e-13 BR00116995 thiostrepton final compound B02 U2OS 24 211 Binuclear +0.3150610066090493 9.63749605386715e-13 BR00117026 CYT-997 final compound E06 U2OS 24 280 Binuclear +0.28426569742941427 1.489241896037657e-12 BR00117026 BI-2536 final compound I14 U2OS 24 339 Binuclear +0.2295761078998073 1.8508739669527157e-12 BR00117024 PF-431396 final compound L20 U2OS 24 519 Binuclear +0.1781180819856269 2.1414668955537317e-12 BR00117025 AC-710 final compound I03 U2OS 24 856 Binuclear +0.25321560933071724 2.4322422107615953e-12 BR00117025 UNC2025 final compound N06 U2OS 24 418 Binuclear +0.2087378640776699 3.3879106397854405e-12 BR00117026 BAN-ORL-24 final compound A15 U2OS 24 618 Binuclear +0.2908602150537634 3.86321378725036e-12 BR00116995 BI-2536 final compound I14 U2OS 24 312 Binuclear +0.25270724421209856 4.104173702243086e-12 BR00117024 BAN-ORL-24 final compound A15 U2OS 24 416 Binuclear +0.23844043887147334 4.410643625780079e-12 BR00117026 UNC2025 final compound N06 U2OS 24 464 Binuclear +0.218845364256783 9.103965367223318e-12 BR00116995 PP-121 final compound B16 U2OS 24 538 Binuclear +0.28072002959559184 1.1823119072430106e-11 BR00117026 KG-5 final compound C13 U2OS 24 319 Binuclear +0.2854449472096531 1.3009073431810184e-11 BR00117024 ixabepilone final compound J21 U2OS 24 306 Binuclear +0.31200994454006503 2.8297774029372592e-11 BR00117024 CYT-997 final compound C09 U2OS 24 249 Binuclear +0.2065214442666088 3.009145587516959e-11 BR00117025 BAN-ORL-24 final compound A15 U2OS 24 579 Binuclear +0.234375 3.353580603634125e-11 BR00117025 ganetespib final compound M10 U2OS 24 448 Binuclear 0.5720946915351507 2.633311519835004e-62 BR00117026 epothilone-b final compound F07 U2OS 24 410 Elongated 0.58133316310608 3.1689976217451396e-59 BR00117024 epothilone-b final compound F07 U2OS 24 372 Elongated 0.5606143433554601 3.289945572470739e-57 BR00117025 epothilone-b final compound F07 U2OS 24 390 Elongated @@ -349,6 +3409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.38815238714030464 1.35907466135333e-33 BR00116995 AMG900 final compound N09 U2OS 24 491 Elongated 0.4904054489494328 1.8159299865704215e-33 BR00117026 puromycin final compound C22 U2OS 24 299 Elongated 0.39556277056277056 5.04828084987312e-33 BR00117026 UNC2025 final compound N06 U2OS 24 464 Elongated +0.47599032833932164 2.9078899035424943e-31 BR00117025 ixabepilone final compound J21 U2OS 24 298 Elongated +0.4131857855361596 4.430654794542768e-31 BR00117024 GSK1070916 final compound C04 U2OS 24 401 Elongated +0.4916370152975093 7.709333027043916e-31 BR00117026 SU3327 final compound I20 U2OS 24 278 Elongated +0.35858347627215553 1.0523205956454114e-30 BR00117025 AMG900 final compound N09 U2OS 24 528 Elongated +0.5007289879931389 1.495231679326403e-30 BR00117024 SU3327 final compound I20 U2OS 24 265 Elongated +0.3830734966592428 9.460136601196162e-30 BR00117026 GSK1070916 final compound C04 U2OS 24 449 Elongated +0.31827784267912773 3.082947520098893e-29 BR00117026 KU-60019 final compound I07 U2OS 24 642 Elongated +0.4725216065073716 5.199095402465974e-29 BR00117026 ixabepilone final compound J21 U2OS 24 280 Elongated +0.3821096233061398 8.887400942769045e-28 BR00117025 UNC2025 final compound N06 U2OS 24 418 Elongated +0.5013504513837502 2.486812058367794e-27 BR00117024 oxibendazole final compound M19 U2OS 24 232 Elongated +0.4566002117373946 9.203837295718271e-27 BR00116995 SU3327 final compound I20 U2OS 24 281 Elongated +0.42576763566268816 1.4465680429232973e-26 BR00117026 KG-5 final compound C13 U2OS 24 319 Elongated +0.45757299270072993 3.162784141975317e-26 BR00116995 puromycin final compound C22 U2OS 24 272 Elongated +0.45169915242907943 8.369720469628651e-26 BR00117025 puromycin final compound C22 U2OS 24 274 Elongated +0.48220047512675956 1.2491610158177305e-25 BR00116995 oxibendazole final compound M19 U2OS 24 238 Elongated +0.48094833249603897 2.581824534305501e-24 BR00117025 SU3327 final compound I20 U2OS 24 226 Elongated +0.43207839092315625 8.14270361919511e-24 BR00117025 KG-5 final compound C13 U2OS 24 277 Elongated +0.2674731182795699 8.261319860050114e-24 BR00117025 PP-2 final compound J10 U2OS 24 744 Elongated +0.42767488137149856 1.7875617728124484e-23 BR00117025 oxibendazole final compound M19 U2OS 24 278 Elongated +0.4396699086354259 2.8259178169732004e-23 BR00116995 ixabepilone final compound J21 U2OS 24 261 Elongated +0.3429640473308988 2.852079861062711e-23 BR00117024 AMG900 final compound N09 U2OS 24 433 Elongated +0.2796891525267853 3.6970556576397545e-23 BR00116995 PP-2 final compound J10 U2OS 24 660 Elongated +0.4598725191945531 4.671495770940759e-23 BR00117024 colchicine final compound K17 U2OS 24 234 Elongated +0.45121951219512196 6.206541809688896e-23 BR00117026 CYT-997 final compound C09 U2OS 24 246 Elongated +0.47575757575757577 7.905022703695775e-23 BR00117024 CYT-997 final compound E06 U2OS 24 220 Elongated +0.4346692306571682 1.101884265331919e-22 BR00117026 NSC-632839 final compound M16 U2OS 24 263 Elongated +0.42243537379114077 1.6124798117946117e-22 BR00117024 thiostrepton final compound B02 U2OS 24 277 Elongated +0.31582085919435315 1.7922146102590266e-22 BR00116995 PF-431396 final compound L20 U2OS 24 498 Elongated +0.4900990099009901 2.247864688845048e-22 BR00117026 AZD7762 final compound I05 U2OS 24 202 Elongated +0.3635512584407612 7.580898232200015e-22 BR00117024 BI-2536 final compound I14 U2OS 24 362 Elongated +0.433687129470262 8.569770756632607e-22 BR00117024 CYT-997 final compound C09 U2OS 24 249 Elongated +0.2955270092226614 1.1341360569287894e-21 BR00117025 PF-431396 final compound L20 U2OS 24 550 Elongated +0.41883482149214624 2.302041217538781e-21 BR00117026 delanzomib final compound L11 U2OS 24 267 Elongated +0.4399302093718844 2.6873184546308845e-21 BR00117025 AZD7762 final compound I05 U2OS 24 236 Elongated +0.3266494145114386 3.00021303379687e-21 BR00116995 danusertib final compound N18 U2OS 24 439 Elongated +0.4048805287239451 3.019327672773781e-21 BR00117026 CYT-997 final compound E06 U2OS 24 280 Elongated +0.48 3.1330954373417528e-21 BR00117024 AZD7762 final compound I05 U2OS 24 200 Elongated +0.3975704286458032 3.2993435915011915e-21 BR00117025 delanzomib final compound L11 U2OS 24 295 Elongated +0.39477549544663637 3.919396524063348e-21 BR00116995 briciclib final compound H01 U2OS 24 297 Elongated +0.40012254901960786 4.600284663328723e-21 BR00117024 briciclib final compound H01 U2OS 24 289 Elongated +0.36840607210626186 5.446679635329433e-21 BR00116995 BI-2536 final compound E21 U2OS 24 340 Elongated +0.4246031746031746 9.391637637831936e-21 BR00116995 colchicine final compound K17 U2OS 24 252 Elongated +0.3949456778460085 9.801041945974152e-21 BR00117025 CYT-997 final compound C09 U2OS 24 290 Elongated +0.2754155392346347 1.52540245821223e-20 BR00116995 BMS-536924 final compound B15 U2OS 24 597 Elongated +0.39956120210214807 1.793567606689012e-20 BR00117024 delanzomib final compound L11 U2OS 24 282 Elongated +0.4304650152107779 3.131889467908682e-20 BR00117024 AZD7762 final compound K11 U2OS 24 234 Elongated +0.3239942446700392 4.4214129805369e-20 BR00117025 GSK1070916 final compound C04 U2OS 24 419 Elongated +0.37338709677419357 6.185199086196044e-20 BR00116995 BI-2536 final compound I14 U2OS 24 312 Elongated +0.4201530612244898 9.081505205459444e-20 BR00117024 NSC-632839 final compound M16 U2OS 24 240 Elongated +0.43790400775694893 1.1207860771918032e-19 BR00117024 puromycin final compound C22 U2OS 24 224 Elongated +0.4170731707317073 1.489468734296536e-19 BR00117025 colchicine final compound K17 U2OS 24 245 Elongated +0.23520864284411083 1.8477891543638694e-19 BR00116995 NVS-PAK1-1 final compound N14 U2OS 24 784 Elongated +0.39892987890735004 2.0090475952321476e-19 BR00117025 briciclib final compound H01 U2OS 24 268 Elongated +0.41818344359020204 3.891758740829573e-19 BR00117025 ponatinib final compound C20 U2OS 24 235 Elongated +0.2885375494071146 5.779400907989924e-19 BR00117026 danusertib final compound N18 U2OS 24 506 Elongated +0.273801066866435 8.584680726125474e-19 BR00117026 PF-431396 final compound L20 U2OS 24 556 Elongated +0.2851612853127087 8.843699106337081e-19 BR00117025 danusertib final compound N18 U2OS 24 508 Elongated +0.3861558082110005 1.2563987030079065e-18 BR00117024 KG-5 final compound C13 U2OS 24 274 Elongated +0.28714859437751006 1.7102760666618026e-18 BR00117025 danusertib final compound E05 U2OS 24 498 Elongated +0.37199618183987593 1.7198002976191055e-18 BR00116995 NSC-632839 final compound M16 U2OS 24 289 Elongated +0.29095899590216745 1.948524398982259e-18 BR00117024 danusertib final compound N18 U2OS 24 482 Elongated +0.28730127382245485 2.0120069154151045e-18 BR00117026 AMG900 final compound N09 U2OS 24 492 Elongated +0.38815826527738667 2.049833576930818e-18 BR00117026 oxibendazole final compound M19 U2OS 24 268 Elongated +0.42111137686358924 2.0539259131689426e-18 BR00117025 NSC-632839 final compound M16 U2OS 24 222 Elongated +0.35403726708074534 2.6060162570880223e-18 BR00117026 thiostrepton final compound B02 U2OS 24 322 Elongated +0.3773151691412827 2.87717342646632e-18 BR00117025 BI-2536 final compound E21 U2OS 24 278 Elongated +0.26453303733851324 3.999332060915081e-18 BR00116995 UNC1999 final compound H19 U2OS 24 569 Elongated +0.2725198357654109 4.1461939155578005e-18 BR00116995 PP-121 final compound B16 U2OS 24 538 Elongated +0.27794575366829705 4.237594970735046e-18 BR00117024 PF-431396 final compound L20 U2OS 24 519 Elongated +0.3496664366229584 5.254545028864782e-18 BR00117024 UNC2025 final compound N06 U2OS 24 322 Elongated +0.2869022869022869 7.600422645569904e-18 BR00117024 danusertib final compound E05 U2OS 24 481 Elongated +0.2416729954322822 9.932840179892173e-18 BR00117025 BMS-536924 final compound B15 U2OS 24 673 Elongated +0.32491186839012925 1.0731280080369246e-17 BR00117026 buparlisib final compound D11 U2OS 24 368 Elongated +0.34754031116016054 1.0805028381781408e-17 BR00117024 BI-2536 final compound E21 U2OS 24 317 Elongated +0.2372961009976792 1.1760567116730695e-17 BR00117024 PP-2 final compound J10 U2OS 24 697 Elongated +0.2789064333366858 3.4005354660058914e-17 BR00117026 danusertib final compound E05 U2OS 24 488 Elongated +0.3782051282051282 3.605691426420096e-17 BR00117026 briciclib final compound H01 U2OS 24 261 Elongated +0.3620110346537722 5.3108138222580687e-17 BR00117026 TG-101348 final compound M20 U2OS 24 283 Elongated +0.3364132874457579 6.37244650262137e-17 BR00117024 TG-101348 final compound M20 U2OS 24 328 Elongated +0.22471314137259146 6.38629067413286e-17 BR00117024 NVS-PAK1-1 final compound N14 U2OS 24 745 Elongated +0.24941686624059403 8.549684588038951e-17 BR00117026 BMS-536924 final compound B15 U2OS 24 593 Elongated +0.24454143898115588 8.812334642606212e-17 BR00116995 WH-4-023 final compound A18 U2OS 24 617 Elongated +0.3269466167970078 9.206900994003684e-17 BR00117025 BI-2536 final compound I14 U2OS 24 340 Elongated +0.35129829367117504 1.0042453998137948e-16 BR00117025 thiostrepton final compound B02 U2OS 24 297 Elongated +0.34124647666771063 1.2312466295462943e-16 BR00116995 UNC2025 final compound N06 U2OS 24 310 Elongated +0.4118354137771614 2.6118151567949334e-16 BR00117026 colchicine final compound K17 U2OS 24 210 Elongated +0.21223599299528828 5.227929306461231e-16 BR00117026 RKI-1447 final compound J04 U2OS 24 786 Elongated +0.3120211464867637 6.974531160658493e-16 BR00117026 7-hydroxystaurosporine final compound L04 U2OS 24 355 Elongated +0.21668909825033647 1.094982893772591e-15 BR00117024 RKI-1447 final compound J04 U2OS 24 743 Elongated +0.21012658227848102 1.1186825784800447e-15 BR00116995 AZ191 final compound I18 U2OS 24 790 Elongated 0.45876168224299063 1.5294852147398264e-61 BR00117025 KU-60019 final compound I07 U2OS 24 642 Grape 0.40018529851761186 1.2362183011415907e-49 BR00117024 KU-60019 final compound I07 U2OS 24 688 Grape 0.40760319314641746 2.773797867601787e-48 BR00117026 KU-60019 final compound I07 U2OS 24 642 Grape @@ -359,6 +3509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.22683605780620705 3.722633901603385e-23 BR00117024 polydatin final compound K08 U2OS 24 1005 Grape 0.34062649450023913 1.231162728511902e-21 BR00117026 epothilone-b final compound F07 U2OS 24 410 Grape 0.28028380475398174 3.950281087704396e-21 BR00116995 BMS-536924 final compound B15 U2OS 24 597 Grape +0.34289990888975663 5.330398919438869e-21 BR00117025 epothilone-b final compound F07 U2OS 24 390 Grape +0.34995176894487473 6.139053065187326e-21 BR00117024 epothilone-b final compound F07 U2OS 24 372 Grape +0.31670281995661603 7.813706199521049e-21 BR00117026 AVL-292 final compound A24 U2OS 24 461 Grape +0.34192156279170444 1.9476096036251508e-20 BR00116995 AVL-292 final compound A24 U2OS 24 383 Grape +0.25659787573606296 5.695359000468746e-20 BR00117025 BMS-536924 final compound B15 U2OS 24 673 Grape +0.30921437329057816 7.103313656317223e-20 BR00117025 WH-4-023 final compound A18 U2OS 24 460 Grape +0.33173432692432525 1.3060240268468065e-19 BR00117025 PP-121 final compound B16 U2OS 24 391 Grape +0.2573345936222746 1.6594780929562006e-18 BR00116995 WH-4-023 final compound A18 U2OS 24 617 Grape +0.260563719585642 3.4967522432384755e-18 BR00117026 BMS-536924 final compound B15 U2OS 24 593 Grape +0.2758707573736475 7.54631919594921e-18 BR00117024 PF-431396 final compound L20 U2OS 24 519 Grape +0.23118279569892472 7.703665723739549e-18 BR00117025 PP-2 final compound J10 U2OS 24 744 Grape +0.23014804845222073 1.1664553687014148e-17 BR00117024 RKI-1447 final compound J04 U2OS 24 743 Grape +0.3194234757947314 1.7166203503584332e-17 BR00117026 PP-121 final compound B16 U2OS 24 374 Grape +0.2881745351942359 9.763534102187265e-17 BR00116995 fludarabine-phosphate final compound N12 U2OS 24 445 Grape +0.27004989655592065 1.974066856303762e-16 BR00116995 PF-431396 final compound L20 U2OS 24 498 Grape +0.2880897138437742 3.4841401640008004e-16 BR00117025 AVL-292 final compound A24 U2OS 24 431 Grape +0.255326527215225 6.122863143601173e-16 BR00116995 PP-121 final compound B16 U2OS 24 538 Grape +0.20689655172413793 5.427227482856071e-14 BR00116995 RKI-1447 final compound J04 U2OS 24 725 Grape +0.248 6.591662713252528e-14 BR00117024 fludarabine-phosphate final compound N12 U2OS 24 500 Grape +0.34523809523809523 1.0277178876338796e-13 BR00116995 colchicine final compound K17 U2OS 24 252 Grape +0.2544642857142857 3.780303860226869e-13 BR00117025 ganetespib final compound M10 U2OS 24 448 Grape +0.2550352384998312 9.546366899609723e-13 BR00117025 ganetespib final compound I17 U2OS 24 431 Grape +0.18644679826673086 9.562502871757598e-13 BR00117026 PP-2 final compound J10 U2OS 24 806 Grape +0.3527777777777778 1.4666020588026574e-12 BR00117024 CYT-997 final compound E06 U2OS 24 220 Grape +0.22900763358778625 1.8678358023070522e-12 BR00117024 AVL-292 final compound A24 U2OS 24 524 Grape +0.18197104423164615 2.3711373654829413e-12 BR00117025 arcyriaflavin-a final compound B04 U2OS 24 817 Grape +0.19700799758188567 2.7745022543394085e-12 BR00117024 PP-2 final compound J10 U2OS 24 697 Grape +0.25346630298897604 2.776772609292225e-12 BR00117026 ganetespib final compound I17 U2OS 24 419 Grape +0.23642557651991614 3.20851675502611e-12 BR00117024 ganetespib final compound M10 U2OS 24 480 Grape +0.1782762691853601 3.5828352369141564e-12 BR00117025 RKI-1447 final compound J04 U2OS 24 847 Grape +0.1773814286817298 4.649096410535049e-12 BR00117026 SB-203580 final compound L08 U2OS 24 843 Grape +0.20388349514563106 1.1882422048138644e-11 BR00117026 BAN-ORL-24 final compound A15 U2OS 24 618 Grape +0.21425295489687343 1.5236756042660947e-11 BR00117026 WH-4-023 final compound A18 U2OS 24 552 Grape +0.23160173160173161 1.9149346988946593e-11 BR00117026 UNC2025 final compound N06 U2OS 24 464 Grape +0.19333011449855153 2.8771754456395587e-11 BR00116995 PP-2 final compound J10 U2OS 24 660 Grape +0.32397883676187655 3.033744967228226e-11 BR00117024 oxibendazole final compound M19 U2OS 24 232 Grape +0.28697489435744467 3.098449106715124e-11 BR00116995 briciclib final compound H01 U2OS 24 297 Grape +0.2880255077940482 4.1864496228820894e-11 BR00117025 CYT-997 final compound C09 U2OS 24 290 Grape +0.21270726129216697 5.5945674872820615e-11 BR00117025 AMG900 final compound N09 U2OS 24 528 Grape +0.23644624969880554 8.237465583565102e-11 BR00117025 UNC2025 final compound N06 U2OS 24 418 Grape +0.2701863354037267 9.569149582681648e-11 BR00117026 thiostrepton final compound B02 U2OS 24 322 Grape +0.2831266901372519 2.0066541652527347e-10 BR00117025 TG-101348 final compound M20 U2OS 24 278 Grape +0.21176470588235294 2.0082367920159143e-10 BR00117026 ganetespib final compound M10 U2OS 24 510 Grape +0.1954057483879819 2.0196470072587316e-10 BR00116995 ganetespib final compound I17 U2OS 24 592 Grape +0.21408939797900003 2.1697197068302096e-10 BR00117026 AMG900 final compound N09 U2OS 24 492 Grape +0.2221366481565057 3.2729936603830576e-10 BR00117024 NVP-HSP990 final compound E23 U2OS 24 451 Grape +0.20848777867311308 3.658614136387953e-10 BR00117025 fludarabine-phosphate final compound N12 U2OS 24 510 Grape +0.27905439755973566 4.4619652595156867e-10 BR00117026 CYT-997 final compound E06 U2OS 24 280 Grape +0.1806410895200133 4.537783547236788e-10 BR00117026 PP-1 final compound A22 U2OS 24 669 Grape +0.15788201285571707 4.783863618963659e-10 BR00117025 SB-203580 final compound L08 U2OS 24 883 Grape +0.2725994809688581 4.858730738495221e-10 BR00117024 briciclib final compound H01 U2OS 24 289 Grape +0.2967479674796748 5.886908095359692e-10 BR00117026 CYT-997 final compound C09 U2OS 24 246 Grape +0.2905431248804743 7.058712888290536e-10 BR00117024 CYT-997 final compound C09 U2OS 24 249 Grape +0.1927949434392209 7.451177891394977e-10 BR00117025 BAN-ORL-24 final compound A15 U2OS 24 579 Grape +0.3160887656033287 1.0628362516896174e-09 BR00117026 colchicine final compound K17 U2OS 24 210 Grape +0.16329113924050634 1.31093345442593e-09 BR00116995 AZ191 final compound I18 U2OS 24 790 Grape +0.2632768361581921 1.6629700307844938e-09 BR00117025 thiostrepton final compound B02 U2OS 24 297 Grape +0.2916123424598001 2.4704788265415975e-09 BR00117024 colchicine final compound K17 U2OS 24 234 Grape +0.2564935064935065 2.6095365550783408e-09 BR00116995 TG-101348 final compound M20 U2OS 24 308 Grape +0.20319990613161687 2.79794712222405e-09 BR00117026 danusertib final compound E05 U2OS 24 488 Grape +0.2687554349258215 2.8801718394761576e-09 BR00117024 thiostrepton final compound B02 U2OS 24 277 Grape +0.20166320166320167 5.703242903827586e-09 BR00117024 danusertib final compound E05 U2OS 24 481 Grape +0.17225828878512575 6.754389827237411e-09 BR00117024 AZ191 final compound I18 U2OS 24 653 Grape +0.2070386713243856 8.228140251559758e-09 BR00117026 NVP-HSP990 final compound E23 U2OS 24 441 Grape +0.15016447506793534 8.466550403670172e-09 BR00116995 BAN-ORL-24 final compound A15 U2OS 24 846 Grape +0.15474704670130324 1.015240733128453e-08 BR00117026 RKI-1447 final compound J04 U2OS 24 786 Grape +0.15923070674848439 1.2476414143543757e-08 BR00117025 lonafarnib final compound F22 U2OS 24 734 Grape +0.17993079584775087 1.3704905045204526e-08 BR00116995 PF-03758309 final compound N21 U2OS 24 578 Grape +0.2367948526111028 1.4344702480844758e-08 BR00117024 TG-101348 final compound M20 U2OS 24 328 Grape +0.15697053638433003 1.5637330044065197e-08 BR00117026 arcyriaflavin-a final compound B04 U2OS 24 751 Grape +0.2705160112825618 2.3557388200695767e-08 BR00117025 colchicine final compound K17 U2OS 24 245 Grape +0.1866700833993384 2.869327095776645e-08 BR00117025 danusertib final compound N18 U2OS 24 508 Grape +0.2153659213998056 2.8871502870798378e-08 BR00117025 homoharringtonine final compound N15 U2OS 24 380 Grape +0.17548957172424773 3.910668199896861e-08 BR00117024 BMS-536924 final compound B15 U2OS 24 571 Grape +0.1856272722232343 5.115200570413431e-08 BR00117025 geldanamycin final compound L01 U2OS 24 502 Grape +0.21729588704726827 5.5457448878356367e-08 BR00117024 ganetespib final compound I17 U2OS 24 362 Grape +0.1800230311282356 6.144240904048184e-08 BR00117026 fludarabine-phosphate final compound N12 U2OS 24 527 Grape +0.2146562308164518 8.617304074989962e-08 BR00117024 BI-2536 final compound I14 U2OS 24 362 Grape +0.19555968946364305 8.992107187263646e-08 BR00117024 AMG900 final compound N09 U2OS 24 433 Grape +0.24199367677143388 8.992655284021003e-08 BR00117026 TG-101348 final compound M20 U2OS 24 283 Grape +0.14318612473594022 9.710481145112969e-08 BR00116995 lonafarnib final compound J06 U2OS 24 813 Grape +0.19993932038834952 9.909473607698482e-08 BR00117024 BAN-ORL-24 final compound A15 U2OS 24 416 Grape +0.17984189723320157 1.4516159766392688e-07 BR00117026 danusertib final compound N18 U2OS 24 506 Grape +0.21586267385039468 1.5540867531649441e-07 BR00117025 7-hydroxystaurosporine final compound L04 U2OS 24 345 Grape +0.24449450858912983 1.7288990334048676e-07 BR00117026 oxibendazole final compound M19 U2OS 24 268 Grape +0.22317181327098282 2.050021537318888e-07 BR00116995 7-hydroxystaurosporine final compound L04 U2OS 24 316 Grape +0.19922913343965976 2.1964843555807022e-07 BR00117024 PP-121 final compound B16 U2OS 24 399 Grape +0.2253645047762695 2.221939105645203e-07 BR00117024 ixabepilone final compound J21 U2OS 24 306 Grape +0.1359344042012025 2.2995653151039436e-07 BR00117025 lonafarnib final compound J06 U2OS 24 853 Grape +0.14754495159059475 2.5194102511378737e-07 BR00117026 lonafarnib final compound J06 U2OS 24 720 Grape 0.6061857707509881 6.986011229860178e-95 BR00117025 PF-431396 final compound L20 U2OS 24 550 Hole 0.6030160091480846 4.901980255928293e-90 BR00117025 AMG900 final compound N09 U2OS 24 528 Hole 0.5812323211448794 2.2376169667411807e-87 BR00117026 PF-431396 final compound L20 U2OS 24 556 Hole @@ -369,6 +3609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5967838354854137 1.62248324147715e-68 BR00117026 epothilone-b final compound F07 U2OS 24 410 Hole 0.5455513091287003 2.8914532508136293e-67 BR00117026 danusertib final compound E05 U2OS 24 488 Hole 0.5467775467775468 2.3328134018251302e-66 BR00117024 danusertib final compound E05 U2OS 24 481 Hole +0.5421123166928687 7.339030781025647e-66 BR00117024 danusertib final compound N18 U2OS 24 482 Hole +0.5326053003136206 4.454956135452534e-64 BR00116995 AMG900 final compound N09 U2OS 24 491 Hole +0.5290971330765939 1.544691318078242e-63 BR00117026 AMG900 final compound N09 U2OS 24 492 Hole +0.5217391304347826 3.0840403751051385e-63 BR00117026 danusertib final compound N18 U2OS 24 506 Hole +0.5779002468295175 1.3391173407545633e-58 BR00117024 epothilone-b final compound F07 U2OS 24 372 Hole +0.5383546223727811 1.6766948357848667e-58 BR00117024 AMG900 final compound N09 U2OS 24 433 Hole +0.5278396436525612 1.5401123933365e-57 BR00117026 GSK1070916 final compound C04 U2OS 24 449 Hole +0.5138817865794761 9.873900223649581e-54 BR00116995 danusertib final compound N18 U2OS 24 439 Hole +0.5377717037615515 2.141254750992429e-52 BR00117025 epothilone-b final compound F07 U2OS 24 390 Hole +0.4804675810473815 2.893695533760215e-42 BR00117024 GSK1070916 final compound C04 U2OS 24 401 Hole +0.4297936259143156 6.57857375665832e-39 BR00117026 UNC2025 final compound N06 U2OS 24 464 Hole +0.4643861734052649 9.553194263365291e-34 BR00116995 epothilone-b final compound F07 U2OS 24 341 Hole +0.4133191054811653 1.2374256759949714e-32 BR00117025 UNC2025 final compound N06 U2OS 24 418 Hole +0.4052026355757043 1.9560541943422408e-31 BR00117025 GSK1070916 final compound C04 U2OS 24 419 Hole +0.3279010903426791 3.94939294151358e-31 BR00117025 KU-60019 final compound I07 U2OS 24 642 Hole +0.31511797905616756 1.1131035306509184e-30 BR00117024 KU-60019 final compound I07 U2OS 24 688 Hole +0.47135506003430533 2.6648708589815603e-27 BR00117024 SU3327 final compound I20 U2OS 24 265 Hole +0.29222644080996885 1.0448856616545553e-24 BR00117026 KU-60019 final compound I07 U2OS 24 642 Hole +0.40993788819875776 1.3601153070073755e-24 BR00117026 thiostrepton final compound B02 U2OS 24 322 Hole +0.39015412928456406 1.736402293566567e-22 BR00117024 UNC2025 final compound N06 U2OS 24 322 Hole +0.40979923642313587 1.5780961277888631e-21 BR00117026 SU3327 final compound I20 U2OS 24 278 Hole +0.3873805932629462 3.3275404595994837e-21 BR00117024 ixabepilone final compound J21 U2OS 24 306 Hole +0.29622883381375203 6.495353016604384e-21 BR00117026 fludarabine-phosphate final compound N12 U2OS 24 527 Hole +0.21114369501466276 2.260400328219285e-20 BR00117025 polydatin final compound K08 U2OS 24 1023 Hole +0.21495327102803738 6.848448164144128e-20 BR00117026 polydatin final compound K08 U2OS 24 963 Hole +0.3795354676710609 1.3122673807508409e-19 BR00117025 thiostrepton final compound B02 U2OS 24 297 Hole +0.3698820336151999 2.5579716645904086e-19 BR00116995 UNC2025 final compound N06 U2OS 24 310 Hole +0.3839334685391395 5.866866431605318e-19 BR00116995 SU3327 final compound I20 U2OS 24 281 Hole +0.3846214656512688 9.680346459461836e-19 BR00117024 thiostrepton final compound B02 U2OS 24 277 Hole +0.41306952119642926 5.905274299856262e-18 BR00117025 SU3327 final compound I20 U2OS 24 226 Hole +0.2414968906499367 1.0505593150355586e-17 BR00117025 BMS-536924 final compound B15 U2OS 24 673 Hole +0.38076928554136225 1.2332717224765608e-17 BR00117026 delanzomib final compound L11 U2OS 24 267 Hole +0.3639726516659013 5.267795934360847e-17 BR00117024 delanzomib final compound L11 U2OS 24 282 Hole +0.34832666711861343 1.1150261195410558e-16 BR00117025 ixabepilone final compound J21 U2OS 24 298 Hole +0.30383501888948033 1.796409668560665e-16 BR00117025 PP-121 final compound B16 U2OS 24 391 Hole +0.38694630394530694 2.5860791720876025e-16 BR00117025 AZD7762 final compound I05 U2OS 24 236 Hole +0.266 5.833972860643141e-16 BR00117024 fludarabine-phosphate final compound N12 U2OS 24 500 Hole +0.1870942904524994 7.353348334904767e-16 BR00117024 polydatin final compound K08 U2OS 24 1005 Hole +0.21241379310344827 9.901963538038053e-15 BR00116995 RKI-1447 final compound J04 U2OS 24 725 Hole +0.29250913606027684 1.0268450003387146e-14 BR00117026 PP-121 final compound B16 U2OS 24 374 Hole +0.1936245572609209 2.69812664609528e-14 BR00117025 RKI-1447 final compound J04 U2OS 24 847 Hole +0.2603036876355748 3.916799199265289e-14 BR00117026 AVL-292 final compound A24 U2OS 24 461 Hole +0.3512361041977767 6.390158899677473e-14 BR00117025 colchicine final compound K17 U2OS 24 245 Hole +0.33237547892720304 2.2307399021005546e-13 BR00116995 ixabepilone final compound J21 U2OS 24 261 Hole +0.38 2.9623487356936016e-13 BR00117024 AZD7762 final compound I05 U2OS 24 200 Hole +0.37623762376237624 4.026483410900558e-13 BR00117026 AZD7762 final compound I05 U2OS 24 202 Hole +0.3182892730045755 5.046884038346185e-13 BR00117026 CYT-997 final compound E06 U2OS 24 280 Hole +0.3558096315449257 5.152593624665185e-13 BR00117024 puromycin final compound C22 U2OS 24 224 Hole +0.19515477792732167 8.725965451119279e-13 BR00117024 RKI-1447 final compound J04 U2OS 24 743 Hole +0.31288822763622837 9.464575445442858e-13 BR00117026 TG-101348 final compound M20 U2OS 24 283 Hole +0.3599864590385917 9.489379655413598e-13 BR00116995 thiostrepton final compound B02 U2OS 24 211 Hole +0.22587110913832326 1.4880068442517812e-12 BR00116995 PP-121 final compound B16 U2OS 24 538 Hole +0.28983235654899825 2.03362033806349e-12 BR00117026 KG-5 final compound C13 U2OS 24 319 Hole +0.2117902135559114 4.026902164315846e-12 BR00117026 BMS-536924 final compound B15 U2OS 24 593 Hole +0.18951612903225806 4.29895916206822e-12 BR00117025 PP-2 final compound J10 U2OS 24 744 Hole +0.2819841388597935 4.907408084100933e-12 BR00117024 TG-101348 final compound M20 U2OS 24 328 Hole +0.22425847051149228 9.867400346682532e-12 BR00117025 fludarabine-phosphate final compound N12 U2OS 24 510 Hole +0.2948096885813149 1.541452481766533e-11 BR00116995 NSC-632839 final compound M16 U2OS 24 289 Hole +0.17909906249092966 1.607726355412417e-11 BR00117026 RKI-1447 final compound J04 U2OS 24 786 Hole +0.2909469543587667 1.7186445380394912e-11 BR00117025 delanzomib final compound L11 U2OS 24 295 Hole +0.30713983945923107 1.8563128343779466e-11 BR00117026 NSC-632839 final compound M16 U2OS 24 263 Hole +0.24095073145757764 2.037649657492755e-11 BR00117025 AVL-292 final compound A24 U2OS 24 431 Hole +0.30952380952380953 4.608628503526758e-11 BR00116995 colchicine final compound K17 U2OS 24 252 Hole +0.2945214772203077 6.539875975027496e-11 BR00117024 KG-5 final compound C13 U2OS 24 274 Hole +0.16763882162184926 7.630295568555476e-11 BR00117026 SB-203580 final compound L08 U2OS 24 843 Hole +0.22654437423370744 8.377207563795073e-11 BR00117025 WH-4-023 final compound A18 U2OS 24 460 Hole +0.24105718842560947 1.1353341859759848e-10 BR00117024 PP-121 final compound B16 U2OS 24 399 Hole +0.2099236641221374 1.6116404279144885e-10 BR00117024 AVL-292 final compound A24 U2OS 24 524 Hole +0.24219754055114381 2.167058689248656e-10 BR00116995 AVL-292 final compound A24 U2OS 24 383 Hole +0.22544642857142858 2.1772291249057009e-10 BR00117025 ganetespib final compound M10 U2OS 24 448 Hole +0.2831215048296899 2.3807071966786603e-10 BR00117026 ixabepilone final compound J21 U2OS 24 280 Hole +0.3028061224489796 2.474137671151509e-10 BR00117024 NSC-632839 final compound M16 U2OS 24 240 Hole +0.24795887047268264 2.937985809312703e-10 BR00117024 BI-2536 final compound I14 U2OS 24 362 Hole +0.285538569671411 2.938120767982772e-10 BR00116995 delanzomib final compound L11 U2OS 24 271 Hole +0.1643334197498858 5.297417942033226e-10 BR00117026 PP-2 final compound J10 U2OS 24 806 Hole +0.21904569960195497 6.382504737476816e-10 BR00116995 fludarabine-phosphate final compound N12 U2OS 24 445 Hole +0.21041666666666667 8.568398554306874e-10 BR00117024 ganetespib final compound M10 U2OS 24 480 Hole +0.17481434554605285 9.1589899575474e-10 BR00117024 PP-2 final compound J10 U2OS 24 697 Hole +0.23131112873380916 1.2773603309808053e-09 BR00117024 RGB-286638 final compound K21 U2OS 24 388 Hole +0.27316114542391917 1.4087140289351147e-09 BR00117025 puromycin final compound C22 U2OS 24 274 Hole +0.15333648779327427 1.6818114936318823e-09 BR00117025 SB-203580 final compound L08 U2OS 24 883 Hole +0.24543801178241687 1.75006627561591e-09 BR00117024 PHA-793887 final compound E13 U2OS 24 341 Hole +0.23099569504235523 1.8638772250293487e-09 BR00117025 homoharringtonine final compound N15 U2OS 24 380 Hole +0.2016704553555163 2.2028973815042964e-09 BR00117025 geldanamycin final compound L01 U2OS 24 502 Hole +0.2199340834185703 2.403600086785002e-09 BR00117026 ganetespib final compound I17 U2OS 24 419 Hole +0.2917572070114443 2.4700462002557773e-09 BR00117024 AZD7762 final compound K11 U2OS 24 234 Hole +0.29132261335651166 2.4710589436211897e-09 BR00117024 colchicine final compound K17 U2OS 24 234 Hole +0.2688122096881221 2.6649870153431223e-09 BR00117026 AZD7762 final compound K11 U2OS 24 275 Hole +0.2405710071639275 4.654045761714778e-09 BR00117026 BI-2536 final compound I14 U2OS 24 339 Hole +0.2651889222842422 5.4691136180221395e-09 BR00116995 puromycin final compound C22 U2OS 24 272 Hole 0.6026679841897233 5.647954929329262e-94 BR00117025 PF-431396 final compound L20 U2OS 24 550 Interphase 0.5381717289719626 1.6834327746934593e-85 BR00117025 KU-60019 final compound I07 U2OS 24 642 Interphase 0.5633371220438371 6.906265771576052e-82 BR00117026 PF-431396 final compound L20 U2OS 24 556 Interphase @@ -379,6 +3709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5323588261449533 3.3804340703334955e-68 BR00117024 PF-431396 final compound L20 U2OS 24 519 Interphase 0.6020825198490173 1.1000885285281415e-66 BR00117025 epothilone-b final compound F07 U2OS 24 390 Interphase 0.536144578313253 6.601218948346878e-66 BR00117025 danusertib final compound E05 U2OS 24 498 Interphase +0.4588858289133687 1.2936829790175845e-65 BR00117024 KU-60019 final compound I07 U2OS 24 688 Interphase +0.5277476054112767 1.5462618539125832e-63 BR00117026 AMG900 final compound N09 U2OS 24 492 Interphase +0.5191997080246626 6.431082039627098e-63 BR00117025 danusertib final compound N18 U2OS 24 508 Interphase +0.449264992211838 9.639962086357198e-59 BR00117026 KU-60019 final compound I07 U2OS 24 642 Interphase +0.6339937434827946 5.511179861290348e-52 BR00117025 puromycin final compound C22 U2OS 24 274 Interphase +0.4743083003952569 7.498444153400342e-52 BR00117026 danusertib final compound N18 U2OS 24 506 Interphase +0.48014097019678836 9.475453132795255e-52 BR00117026 danusertib final compound E05 U2OS 24 488 Interphase +0.5062757304950296 1.883152007369381e-51 BR00117024 AMG900 final compound N09 U2OS 24 433 Interphase +0.48232848232848236 4.737795072856872e-51 BR00117024 danusertib final compound E05 U2OS 24 481 Interphase +0.4798286985730608 6.371285331515836e-51 BR00117024 danusertib final compound N18 U2OS 24 482 Interphase +0.47336723601514374 4.24191672083554e-50 BR00116995 AMG900 final compound N09 U2OS 24 491 Interphase +0.5089669890881553 9.60499421893709e-50 BR00117025 UNC2025 final compound N06 U2OS 24 418 Interphase +0.5907843420482449 2.3275326774837815e-49 BR00117026 puromycin final compound C22 U2OS 24 299 Interphase +0.4748283325869533 1.1815462961994275e-47 BR00117026 UNC2025 final compound N06 U2OS 24 464 Interphase +0.4729621537301329 3.09657507626049e-45 BR00116995 danusertib final compound N18 U2OS 24 439 Interphase +0.46993318485523383 3.532410632606726e-45 BR00117026 GSK1070916 final compound C04 U2OS 24 449 Interphase +0.6206150545324512 2.2692603172751426e-43 BR00117025 ponatinib final compound C20 U2OS 24 235 Interphase +0.503365289777883 9.053078463697977e-42 BR00117026 7-hydroxystaurosporine final compound L04 U2OS 24 355 Interphase +0.6083891183592081 1.0455715096454721e-41 BR00117025 AZD7762 final compound I05 U2OS 24 236 Interphase +0.3679203125859887 4.53845476077855e-41 BR00117025 BMS-536924 final compound B15 U2OS 24 673 Interphase +0.2981427174975562 1.6687429095544917e-40 BR00117025 polydatin final compound K08 U2OS 24 1023 Interphase +0.537062532538902 2.914425660434117e-39 BR00117025 delanzomib final compound L11 U2OS 24 295 Interphase +0.5383996052255668 2.9558872847685985e-37 BR00117026 SU3327 final compound I20 U2OS 24 278 Interphase +0.4819814813231535 1.9994257651962782e-36 BR00116995 epothilone-b final compound F07 U2OS 24 341 Interphase +0.4683895904730607 7.602099808149094e-36 BR00117024 7-hydroxystaurosporine final compound L04 U2OS 24 358 Interphase +0.5666739098942489 1.3389096150014862e-35 BR00117024 AZD7762 final compound K11 U2OS 24 234 Interphase +0.5346912521440823 5.176888033490385e-35 BR00117024 SU3327 final compound I20 U2OS 24 265 Interphase +0.3225806451612903 1.2394804513489546e-34 BR00117025 PP-2 final compound J10 U2OS 24 744 Interphase +0.48851084415060875 1.6037979874302572e-34 BR00116995 7-hydroxystaurosporine final compound L04 U2OS 24 316 Interphase +0.2824506749740395 3.1281163601414856e-34 BR00117026 polydatin final compound K08 U2OS 24 963 Interphase +0.5452091767881242 4.998260880092651e-34 BR00117025 AZD7762 final compound K11 U2OS 24 247 Interphase +0.5612899486030065 9.135421501973143e-34 BR00117025 SU3327 final compound I20 U2OS 24 226 Interphase +0.5113337757133377 4.0275372122686957e-33 BR00117026 AZD7762 final compound K11 U2OS 24 275 Interphase +0.3503252228378704 5.610686835394484e-33 BR00117026 BMS-536924 final compound B15 U2OS 24 593 Interphase +0.48596491228070177 8.184194005734205e-33 BR00117025 NSC-663284 final compound G06 U2OS 24 304 Interphase +0.5064673679690854 1.389462235355868e-32 BR00116995 puromycin final compound C22 U2OS 24 272 Interphase +0.4763700351935646 2.4461386984215487e-32 BR00117024 ixabepilone final compound J21 U2OS 24 306 Interphase +0.4995854538960956 3.4258229106255434e-32 BR00116995 SU3327 final compound I20 U2OS 24 281 Interphase +0.423844885559609 4.4470865052703186e-32 BR00117025 PP-121 final compound B16 U2OS 24 391 Interphase +0.49048420837797846 3.207347121565074e-31 BR00117024 delanzomib final compound L11 U2OS 24 282 Interphase +0.5742574257425742 4.083236807161733e-31 BR00117026 AZD7762 final compound I05 U2OS 24 202 Interphase +0.455521472392638 4.644846592149909e-31 BR00117024 TG-101348 final compound M20 U2OS 24 328 Interphase +0.575 6.7854964852395645e-31 BR00117024 AZD7762 final compound I05 U2OS 24 200 Interphase +0.45462333768180846 1.53846021197237e-30 BR00117026 KG-5 final compound C13 U2OS 24 319 Interphase +0.3356862349652387 1.7566673360313823e-30 BR00116995 BMS-536924 final compound B15 U2OS 24 597 Interphase +0.4968029506842682 3.1211036709044102e-30 BR00117026 delanzomib final compound L11 U2OS 24 267 Interphase +0.4056920199501247 6.0496238892789586e-30 BR00117024 GSK1070916 final compound C04 U2OS 24 401 Interphase +0.38739474744834046 3.109783836504895e-29 BR00117025 AVL-292 final compound A24 U2OS 24 431 Interphase +0.40822315973643 1.1505691136556495e-28 BR00117026 PP-121 final compound B16 U2OS 24 374 Interphase +0.45394736842105265 1.329320701636281e-28 BR00117026 NSC-663284 final compound G06 U2OS 24 304 Interphase +0.2807488611532906 1.8961184633083157e-28 BR00117026 PP-2 final compound J10 U2OS 24 806 Interphase +0.5226042340012929 3.2213437058850163e-28 BR00117024 puromycin final compound C22 U2OS 24 224 Interphase +0.33905287687954283 5.939428671365384e-28 BR00116995 PP-121 final compound B16 U2OS 24 538 Interphase +0.4455743113461234 2.716096044823043e-27 BR00117025 ixabepilone final compound J21 U2OS 24 298 Interphase +0.24424899312959014 6.75596270513052e-27 BR00117024 polydatin final compound K08 U2OS 24 1005 Interphase +0.5391424125704666 7.467174350117517e-27 BR00117026 ponatinib final compound C20 U2OS 24 199 Interphase +0.3741135764122826 9.492205917179728e-27 BR00117025 GSK1070916 final compound C04 U2OS 24 419 Interphase +0.3079180882010248 1.829356274789726e-26 BR00116995 WH-4-023 final compound A18 U2OS 24 617 Interphase +0.4494617072299607 5.826681830432323e-26 BR00117025 TG-101348 final compound M20 U2OS 24 278 Interphase +0.38608526593528675 8.40069788656306e-26 BR00117025 homoharringtonine final compound N15 U2OS 24 380 Interphase +0.4042851772960782 9.950403174990912e-26 BR00117025 7-hydroxystaurosporine final compound L04 U2OS 24 345 Interphase +0.4156698105973468 1.1782044105476394e-25 BR00117024 UNC2025 final compound N06 U2OS 24 322 Interphase +0.41883116883116883 1.3772866758285508e-24 BR00116995 TG-101348 final compound M20 U2OS 24 308 Interphase +0.46743197278911564 1.9101715226260162e-24 BR00117024 NSC-632839 final compound M16 U2OS 24 240 Interphase +0.34273318872017355 2.1221125488613313e-24 BR00117026 AVL-292 final compound A24 U2OS 24 461 Interphase +0.3660287081339713 3.311953609487459e-24 BR00117024 PP-121 final compound B16 U2OS 24 399 Interphase +0.5609756097560976 4.114302702575417e-24 BR00117024 ponatinib final compound C20 U2OS 24 164 Interphase +0.3397623314156371 5.2393928479271075e-24 BR00117025 WH-4-023 final compound A18 U2OS 24 460 Interphase +0.4118175174861677 6.224769777962249e-24 BR00116995 UNC2025 final compound N06 U2OS 24 310 Interphase +0.4265823569524518 7.174727021986492e-24 BR00117026 TG-101348 final compound M20 U2OS 24 283 Interphase +0.5252822483785732 1.1196410400438793e-23 BR00116995 ponatinib final compound C20 U2OS 24 181 Interphase +0.46047917599641736 6.72264585054404e-23 BR00117024 ryuvidine final compound A14 U2OS 24 231 Interphase +0.4221763795771016 7.620486513289752e-23 BR00117025 KG-5 final compound C13 U2OS 24 277 Interphase +0.415308734469626 2.0562592924795358e-22 BR00117024 NSC-663284 final compound G06 U2OS 24 285 Interphase +0.46268835206888304 3.5974443044285234e-22 BR00117025 NSC-632839 final compound M16 U2OS 24 222 Interphase +0.25923924632676426 4.566219045891944e-21 BR00117024 PP-2 final compound J10 U2OS 24 697 Interphase +0.40382162355222206 5.622991205010962e-21 BR00117025 oxibendazole final compound M19 U2OS 24 278 Interphase +0.503256704980843 5.916305250115878e-21 BR00117026 ryuvidine final compound A14 U2OS 24 174 Interphase +0.41672561155319776 6.141343232649884e-21 BR00116995 ixabepilone final compound J21 U2OS 24 261 Interphase +0.48359929078014185 1.2314119649276692e-20 BR00117025 ryuvidine final compound A14 U2OS 24 192 Interphase +0.39772496187086936 1.729185424955098e-20 BR00117026 ixabepilone final compound J21 U2OS 24 280 Interphase +0.34000054113286166 2.6452903971373883e-20 BR00116995 AVL-292 final compound A24 U2OS 24 383 Interphase +0.6060606060606061 3.356834158939253e-20 BR00117025 LDN-212854 final compound K01 U2OS 24 110 Interphase +0.3463474524248005 9.279566005020139e-20 BR00117024 BI-2536 final compound I14 U2OS 24 362 Interphase +0.2567825447188118 1.5219402445628277e-19 BR00116995 PP-2 final compound J10 U2OS 24 660 Interphase +0.38198305691444934 1.6576285491911438e-19 BR00116995 NSC-632839 final compound M16 U2OS 24 289 Interphase +0.2862595419847328 2.558718297168688e-19 BR00117024 AVL-292 final compound A24 U2OS 24 524 Interphase +0.2778422045758314 2.699049933605829e-19 BR00117026 WH-4-023 final compound A18 U2OS 24 552 Interphase +0.3901842315126448 4.02837948648437e-19 BR00116995 delanzomib final compound L11 U2OS 24 271 Interphase +0.34845290717443045 5.161355719171322e-19 BR00117025 BI-2536 final compound I14 U2OS 24 340 Interphase 0.8533317036855965 1.1231439391424946e-112 BR00117026 puromycin final compound C22 U2OS 24 299 Large 0.8639794168096054 3.4296488384768183e-103 BR00117024 SU3327 final compound I20 U2OS 24 265 Large 0.835458944947996 1.711614567015045e-97 BR00117025 puromycin final compound C22 U2OS 24 274 Large @@ -389,6 +3809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.8512241054613936 2.905698564381459e-88 BR00117024 AZD7762 final compound K11 U2OS 24 234 Large 0.848240991311779 3.589081661318382e-88 BR00117025 AZD7762 final compound I05 U2OS 24 236 Large 0.7996018579960186 5.663668009719321e-88 BR00117026 AZD7762 final compound K11 U2OS 24 275 Large +0.7927779691067488 6.268807629763621e-88 BR00116995 SU3327 final compound I20 U2OS 24 281 Large +0.8437868764527088 6.9489181459806785e-87 BR00117025 ponatinib final compound C20 U2OS 24 235 Large +0.5146963824289406 1.6170033692442085e-83 BR00117024 KU-60019 final compound I07 U2OS 24 688 Large +0.7519407647365072 3.06737713891907e-82 BR00117025 delanzomib final compound L11 U2OS 24 295 Large +0.8811881188118812 3.501514230312645e-82 BR00117026 AZD7762 final compound I05 U2OS 24 202 Large +0.7730249033920137 3.105684686300899e-81 BR00116995 puromycin final compound C22 U2OS 24 272 Large +0.88 4.359302419892892e-81 BR00117024 AZD7762 final compound I05 U2OS 24 200 Large +0.7383333333333333 1.7252874568277457e-80 BR00117025 NSC-663284 final compound G06 U2OS 24 304 Large +0.732766977907036 7.655366725239334e-74 BR00117024 delanzomib final compound L11 U2OS 24 282 Large +0.8281764150702753 4.0478286620316456e-69 BR00117026 ponatinib final compound C20 U2OS 24 199 Large +0.6875 7.127836292227694e-69 BR00117026 NSC-663284 final compound G06 U2OS 24 304 Large +0.47757496105919 6.455176357765166e-67 BR00117026 KU-60019 final compound I07 U2OS 24 642 Large +0.7452978056426333 1.1885832040293135e-63 BR00117024 ryuvidine final compound A14 U2OS 24 231 Large +0.814316598606774 7.3170122182356396e-62 BR00116995 ponatinib final compound C20 U2OS 24 181 Large +0.7120748299319728 5.30739993833784e-60 BR00117024 NSC-632839 final compound M16 U2OS 24 240 Large +0.6725623389014682 9.273911133669462e-58 BR00117026 delanzomib final compound L11 U2OS 24 267 Large +0.7219416612798966 6.267600256535608e-57 BR00117024 puromycin final compound C22 U2OS 24 224 Large +0.8170731707317073 2.3879019347927295e-55 BR00117024 ponatinib final compound C20 U2OS 24 164 Large +0.6035233411271467 2.995235393256608e-54 BR00116995 7-hydroxystaurosporine final compound L04 U2OS 24 316 Large +0.566671361281943 8.573491843636223e-54 BR00117024 7-hydroxystaurosporine final compound L04 U2OS 24 358 Large +0.6098675575706957 4.365858437496584e-51 BR00116995 NSC-632839 final compound M16 U2OS 24 289 Large +0.7626436781609195 5.0373616511846156e-51 BR00117026 ryuvidine final compound A14 U2OS 24 174 Large +0.614596990697384 2.276994493059652e-50 BR00117024 NSC-663284 final compound G06 U2OS 24 285 Large +0.7117686170212766 3.56090159004421e-47 BR00117025 ryuvidine final compound A14 U2OS 24 192 Large +0.6611655903691301 4.829059817635861e-47 BR00117025 NSC-632839 final compound M16 U2OS 24 222 Large +0.448 1.506661131572923e-45 BR00117024 fludarabine-phosphate final compound N12 U2OS 24 500 Large +0.5216948751331518 9.99691986262498e-45 BR00117026 7-hydroxystaurosporine final compound L04 U2OS 24 355 Large +0.5913791006041929 1.4783796518676054e-44 BR00116995 delanzomib final compound L11 U2OS 24 271 Large +0.5961132234896493 4.543933377629244e-44 BR00117026 NSC-632839 final compound M16 U2OS 24 263 Large +0.5062810580573475 1.0836832912610975e-42 BR00117025 UNC1999 final compound H19 U2OS 24 362 Large +0.40641322110196404 1.7609787993359533e-42 BR00116995 UNC1999 final compound H19 U2OS 24 569 Large +0.4498261702020456 5.219279314924342e-41 BR00116995 fludarabine-phosphate final compound N12 U2OS 24 445 Large +0.504297994269341 9.799860051997579e-41 BR00117026 UNC1999 final compound H19 U2OS 24 349 Large +0.8242424242424242 6.6349773046794965e-40 BR00117025 LDN-212854 final compound K01 U2OS 24 110 Large +0.774074074074074 9.480392282482029e-40 BR00117026 LDN-212854 final compound K01 U2OS 24 135 Large +0.42112212045864417 1.405790615600228e-39 BR00116995 AMG900 final compound N09 U2OS 24 491 Large +0.43010752688172044 5.496792265784174e-39 BR00117024 UNC1999 final compound H19 U2OS 24 465 Large +0.41566265060240964 6.55278687531934e-39 BR00117025 danusertib final compound E05 U2OS 24 498 Large +0.31018113369549066 1.2087389540503505e-36 BR00117026 AC-710 final compound I03 U2OS 24 853 Large +0.7512718023255814 2.6269754897162138e-36 BR00117024 LDN-212854 final compound K01 U2OS 24 129 Large +0.39723320158102765 4.8712517114726174e-36 BR00117026 danusertib final compound N18 U2OS 24 506 Large +0.39468170829975824 5.595138473234828e-36 BR00117025 fludarabine-phosphate final compound N12 U2OS 24 510 Large +0.5111910061062603 6.263582708307244e-36 BR00117025 thiostrepton final compound B02 U2OS 24 297 Large +0.3878644784680679 7.034783028495207e-36 BR00117026 fludarabine-phosphate final compound N12 U2OS 24 527 Large +0.3827966809679566 3.8837105627993116e-35 BR00117024 JTE-607 final compound C14 U2OS 24 532 Large +0.48757763975155277 4.5032461220426734e-35 BR00117026 thiostrepton final compound B02 U2OS 24 322 Large +0.3856792309245368 2.596823026290706e-34 BR00117025 danusertib final compound N18 U2OS 24 508 Large +0.3935892922994401 3.0410478146618758e-34 BR00117026 danusertib final compound E05 U2OS 24 488 Large +0.35779784886927746 3.978869352537999e-34 BR00117025 azeliragon final compound C08 U2OS 24 588 Large +0.4059008569259139 6.024784684169083e-33 BR00116995 danusertib final compound N18 U2OS 24 439 Large +0.38818587149815725 6.983546805690081e-33 BR00117024 danusertib final compound N18 U2OS 24 482 Large +0.3312892361707406 5.289507711413845e-32 BR00117026 azeliragon final compound C08 U2OS 24 648 Large +0.2720664589823468 9.266441112039419e-32 BR00117026 polydatin final compound K08 U2OS 24 963 Large +0.3804573804573805 2.1012102381577046e-31 BR00117024 danusertib final compound E05 U2OS 24 481 Large +0.3422818791946309 2.407054129193643e-31 BR00117024 azeliragon final compound C08 U2OS 24 596 Large +0.3830734966592428 9.460136601196162e-30 BR00117026 GSK1070916 final compound C04 U2OS 24 449 Large +0.3624140087554722 2.8286873280646803e-29 BR00117026 AMG900 final compound N09 U2OS 24 492 Large +0.34684105202973126 8.820864464323568e-29 BR00117025 AMG900 final compound N09 U2OS 24 528 Large +0.2525142146410803 1.1545205709832042e-28 BR00117024 polydatin final compound K08 U2OS 24 1005 Large +0.42130894207075137 5.396722104424943e-28 BR00117025 7-hydroxystaurosporine final compound L04 U2OS 24 345 Large +0.24731182795698925 7.193793993306202e-28 BR00117025 polydatin final compound K08 U2OS 24 1023 Large +0.38626558603491273 2.5947460321057287e-27 BR00117024 GSK1070916 final compound C04 U2OS 24 401 Large +0.30620436085049035 5.586357409928302e-27 BR00117025 NVP-ADW742 final compound D16 U2OS 24 641 Large +0.3743933493964897 8.851244965847925e-27 BR00117025 GSK1070916 final compound C04 U2OS 24 419 Large +0.456705051516509 1.4510958992121585e-26 BR00117024 thiostrepton final compound B02 U2OS 24 277 Large +0.30751472197613217 2.1695188866567585e-26 BR00117026 NVP-ADW742 final compound D16 U2OS 24 620 Large +0.2563236785570181 2.7219562364119645e-25 BR00117025 AC-710 final compound I03 U2OS 24 856 Large +0.3244274809160305 8.584700992924441e-25 BR00117024 AVL-292 final compound A24 U2OS 24 524 Large +0.2373457760156017 1.3484944847054495e-23 BR00117024 AC-710 final compound I03 U2OS 24 931 Large +0.3448930087041079 1.7334748825790132e-23 BR00117024 AMG900 final compound N09 U2OS 24 433 Large +0.32074745687748785 3.52933110769583e-22 BR00117025 BAX-channel-blocker final compound I19 U2OS 24 475 Large +0.4333665173386428 3.961880172763401e-21 BR00117025 colchicine final compound K17 U2OS 24 245 Large +0.2987068326663702 6.223664320061466e-21 BR00117024 PF-431396 final compound L20 U2OS 24 519 Large +0.28421052631578947 1.1096490909557572e-20 BR00116995 NVP-ADW742 final compound D16 U2OS 24 570 Large +0.2544885830466062 3.42625627624978e-20 BR00117026 JTE-607 final compound C14 U2OS 24 695 Large +0.3970005083884087 3.530377848551386e-20 BR00117026 CYT-997 final compound E06 U2OS 24 280 Large +0.33363712311080734 3.561992331395957e-20 BR00117024 PP-121 final compound B16 U2OS 24 399 Large +0.2985152732140684 5.3650909701753025e-20 BR00116995 PF-431396 final compound L20 U2OS 24 498 Large +0.22452319056392653 3.497394070817289e-19 BR00116995 BAN-ORL-24 final compound A15 U2OS 24 846 Large +0.3036876355748373 3.652627215979524e-19 BR00117026 AVL-292 final compound A24 U2OS 24 461 Large +0.2752638104955892 4.895186324535297e-19 BR00117026 PF-431396 final compound L20 U2OS 24 556 Large +0.3177819887473535 6.88257919721717e-19 BR00117026 BAX-channel-blocker final compound I19 U2OS 24 414 Large +0.34772603403379154 8.70393001090926e-19 BR00117024 anisomycin final compound N03 U2OS 24 343 Large +0.24074271058634425 1.2509610429483503e-18 BR00117024 NVP-ADW742 final compound D16 U2OS 24 711 Large +0.37999387723863465 1.3572204889344969e-18 BR00117025 TG-101348 final compound M20 U2OS 24 278 Large +0.3051806585841421 3.6514010406965876e-18 BR00117025 AVL-292 final compound A24 U2OS 24 431 Large +0.3091837926960676 4.744840305634012e-17 BR00117025 PP-121 final compound B16 U2OS 24 391 Large +0.22580645161290322 4.946227961305197e-17 BR00117025 PP-2 final compound J10 U2OS 24 744 Large +0.33413137812359717 8.776267329189605e-17 BR00117024 TG-101348 final compound M20 U2OS 24 328 Large +0.25847167325428194 1.0308552009023199e-16 BR00117025 PF-431396 final compound L20 U2OS 24 550 Large 0.5105435674450955 6.1438052913954725e-59 BR00116995 AMG900 final compound N09 U2OS 24 491 Metaphase 0.554699690753823 1.2373219059909448e-53 BR00117024 epothilone-b final compound F07 U2OS 24 372 Metaphase 0.5236011477761836 5.4472838724223134e-52 BR00117026 epothilone-b final compound F07 U2OS 24 410 Metaphase @@ -399,6 +3909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.4705133151183008 4.910565376195743e-44 BR00117024 AMG900 final compound N09 U2OS 24 433 Metaphase 0.48460236886632824 3.134030706923772e-42 BR00117025 epothilone-b final compound F07 U2OS 24 390 Metaphase 0.4365904365904366 1.433741556273235e-41 BR00117024 danusertib final compound E05 U2OS 24 481 Metaphase +0.45421205688045907 2.4065089697824536e-41 BR00116995 danusertib final compound N18 U2OS 24 439 Metaphase +0.42369612467032636 3.0146322473997265e-39 BR00117024 danusertib final compound N18 U2OS 24 482 Metaphase +0.40695123758707574 6.84938782135184e-39 BR00117024 PF-431396 final compound L20 U2OS 24 519 Metaphase +0.45849127182044885 1.02217528352615e-38 BR00117024 GSK1070916 final compound C04 U2OS 24 401 Metaphase +0.40963855421686746 9.089611931449368e-38 BR00117025 danusertib final compound E05 U2OS 24 498 Metaphase +0.40491000015530604 1.06761935825116e-37 BR00117025 danusertib final compound N18 U2OS 24 508 Metaphase +0.4051383399209486 1.6310081210968549e-37 BR00117026 danusertib final compound N18 U2OS 24 506 Metaphase +0.3987278233106218 1.5083494546604362e-35 BR00117026 AMG900 final compound N09 U2OS 24 492 Metaphase +0.49051030668677725 2.75094163997225e-34 BR00117024 ixabepilone final compound J21 U2OS 24 306 Metaphase +0.36992753623188407 5.444201524961213e-34 BR00117025 PF-431396 final compound L20 U2OS 24 550 Metaphase +0.48916457641289857 6.168885294610234e-33 BR00117025 ixabepilone final compound J21 U2OS 24 298 Metaphase +0.5043467208947636 6.861542141009272e-33 BR00117026 ixabepilone final compound J21 U2OS 24 280 Metaphase +0.39115912822809373 2.862856103304442e-32 BR00117026 UNC2025 final compound N06 U2OS 24 464 Metaphase +0.3817761239062657 3.045897924457449e-32 BR00117026 danusertib final compound E05 U2OS 24 488 Metaphase +0.48559419700359296 3.1837760091193915e-32 BR00116995 briciclib final compound H01 U2OS 24 297 Metaphase +0.34217222272451336 2.6401289639016427e-29 BR00117026 PF-431396 final compound L20 U2OS 24 556 Metaphase +0.4779840848806366 1.5912947412294776e-27 BR00116995 ixabepilone final compound J21 U2OS 24 261 Metaphase +0.4671397172550403 2.181714440647128e-27 BR00117024 KG-5 final compound C13 U2OS 24 274 Metaphase +0.3721209076063994 1.9459193832534206e-26 BR00117025 GSK1070916 final compound C04 U2OS 24 419 Metaphase +0.42222395295858567 4.4148085891178605e-26 BR00117026 KG-5 final compound C13 U2OS 24 319 Metaphase +0.48359109072073403 4.799683635343562e-25 BR00117024 oxibendazole final compound M19 U2OS 24 232 Metaphase +0.4058983192400042 1.6464001250306556e-23 BR00116995 UNC2025 final compound N06 U2OS 24 310 Metaphase +0.42209902011346057 8.059265867176886e-23 BR00117025 KG-5 final compound C13 U2OS 24 277 Metaphase +0.473989898989899 8.584688025273115e-23 BR00117024 CYT-997 final compound E06 U2OS 24 220 Metaphase +0.4349593495934959 2.773614839906396e-21 BR00117026 CYT-997 final compound C09 U2OS 24 246 Metaphase +0.40012254901960786 4.600284663328723e-21 BR00117024 briciclib final compound H01 U2OS 24 289 Metaphase +0.41168684877499295 7.390297539460517e-21 BR00117026 oxibendazole final compound M19 U2OS 24 268 Metaphase +0.40913645741231947 3.29269601722947e-20 BR00117026 briciclib final compound H01 U2OS 24 261 Metaphase +0.42770272666028436 3.31609461186638e-20 BR00116995 oxibendazole final compound M19 U2OS 24 238 Metaphase +0.4166666666666667 5.624042738278987e-20 BR00116995 colchicine final compound K17 U2OS 24 252 Metaphase +0.4004083356800901 1.0061829230828467e-19 BR00117025 briciclib final compound H01 U2OS 24 268 Metaphase +0.4248152976966536 1.7876959872817191e-19 BR00117024 colchicine final compound K17 U2OS 24 234 Metaphase +0.31798675891822425 2.857015620491486e-19 BR00117025 UNC2025 final compound N06 U2OS 24 418 Metaphase +0.37277580071174377 5.325779165042473e-18 BR00117026 CYT-997 final compound E06 U2OS 24 280 Metaphase +0.33613075728825254 1.7128908396655935e-17 BR00116995 BI-2536 final compound E21 U2OS 24 340 Metaphase +0.39303135888501745 1.9834370970283095e-17 BR00117025 colchicine final compound K17 U2OS 24 245 Metaphase +0.36072272083136514 2.504830130917432e-17 BR00117025 CYT-997 final compound C09 U2OS 24 290 Metaphase +0.3447477253928867 5.0915563027801725e-17 BR00116995 BI-2536 final compound I14 U2OS 24 312 Metaphase +0.2189873417721519 5.30200674242041e-17 BR00116995 AZ191 final compound I18 U2OS 24 790 Metaphase +0.33971704623878535 5.355612300975521e-17 BR00117024 UNC2025 final compound N06 U2OS 24 322 Metaphase +0.38396442914515205 5.808546642835726e-17 BR00117024 CYT-997 final compound C09 U2OS 24 249 Metaphase +0.41423948220064727 1.4360986271882055e-16 BR00117026 colchicine final compound K17 U2OS 24 210 Metaphase +0.3111878453038674 5.036205887300395e-16 BR00117024 BI-2536 final compound I14 U2OS 24 362 Metaphase +0.352594520128578 5.898631207897559e-16 BR00117025 oxibendazole final compound M19 U2OS 24 278 Metaphase +0.3030846063454759 2.0299054967234326e-15 BR00117026 buparlisib final compound D11 U2OS 24 368 Metaphase +0.3167701863354037 1.114384140183794e-14 BR00117026 thiostrepton final compound B02 U2OS 24 322 Metaphase +0.28268569918054454 3.485116833559578e-14 BR00117024 RGB-286638 final compound K21 U2OS 24 388 Metaphase +0.3017541087231353 3.9650131555025495e-14 BR00117026 BI-2536 final compound I14 U2OS 24 339 Metaphase +0.3221476510067114 4.4791922173258693e-14 BR00117026 BI-2536 final compound E21 U2OS 24 298 Metaphase +0.2244062244062244 1.295796307861374e-13 BR00117026 AZ191 final compound I18 U2OS 24 592 Metaphase +0.303317674404977 1.6136526605513346e-13 BR00117024 BI-2536 final compound E21 U2OS 24 317 Metaphase +0.3941193941193941 3.245996667607094e-13 BR00117025 CYT-997 final compound E06 U2OS 24 182 Metaphase +0.30224458204334365 6.831102756810226e-13 BR00116995 buparlisib final compound D11 U2OS 24 304 Metaphase +0.3100985679747071 1.2784695270122665e-12 BR00117026 TG-101348 final compound M20 U2OS 24 283 Metaphase +0.31083292210996544 2.6077660664985596e-12 BR00117026 SU3327 final compound I20 U2OS 24 278 Metaphase +0.27873563218390807 2.626755563608005e-12 BR00117026 RGB-286638 final compound K21 U2OS 24 348 Metaphase +0.3067865393019916 2.8977068566327005e-12 BR00117024 buparlisib final compound L12 U2OS 24 285 Metaphase +0.20140409060588693 5.087401352899943e-12 BR00117024 AZ191 final compound I18 U2OS 24 653 Metaphase +0.2460279274655718 6.226223790593253e-12 BR00116995 RGB-286638 final compound K21 U2OS 24 432 Metaphase +0.3088235294117647 7.41951941420021e-12 BR00117025 buparlisib final compound D11 U2OS 24 272 Metaphase +0.2736654199251955 8.108968623804743e-12 BR00117025 BI-2536 final compound I14 U2OS 24 340 Metaphase +0.18165839132587902 9.757101541357578e-12 BR00116995 NVS-PAK1-1 final compound N14 U2OS 24 784 Metaphase +0.1949188393801444 1.746006019599057e-11 BR00116995 PP-2 final compound J10 U2OS 24 660 Metaphase +0.32693343593689883 2.57973834754248e-11 BR00117026 buparlisib final compound L12 U2OS 24 226 Metaphase +0.2945400405807795 4.860392084503844e-11 BR00117024 thiostrepton final compound B02 U2OS 24 277 Metaphase +0.2913413949691311 5.403942065277855e-11 BR00117025 BI-2536 final compound E21 U2OS 24 278 Metaphase +0.17900403768506057 8.178610059707265e-11 BR00117024 RKI-1447 final compound J04 U2OS 24 743 Metaphase +0.29128842172320435 8.352694781363588e-11 BR00117024 buparlisib final compound D11 U2OS 24 276 Metaphase +0.29179531160663236 2.0548490956833895e-10 BR00117024 SU3327 final compound I20 U2OS 24 265 Metaphase +0.1814838300570704 4.2059574103111116e-10 BR00116995 PP-1 final compound A22 U2OS 24 664 Metaphase +0.18199144753390994 8.483245409483179e-10 BR00117025 AZ191 final compound I18 U2OS 24 644 Metaphase +0.16429628769628188 9.472444212436042e-10 BR00117026 RKI-1447 final compound J04 U2OS 24 786 Metaphase +0.1685123042505593 1.0926301802863937e-09 BR00117024 NVS-PAK1-1 final compound N14 U2OS 24 745 Metaphase +0.26536551960280774 1.1211872950238058e-09 BR00117025 thiostrepton final compound B02 U2OS 24 297 Metaphase +0.31146468065899346 1.3038087068664772e-09 BR00116995 thiostrepton final compound B02 U2OS 24 211 Metaphase +0.1696551724137931 1.587478853079124e-09 BR00116995 RKI-1447 final compound J04 U2OS 24 725 Metaphase +0.2564935064935065 2.6095365550783408e-09 BR00116995 TG-101348 final compound M20 U2OS 24 308 Metaphase +0.1549242982585441 2.7177449458971706e-09 BR00117026 sotrastaurin final compound K12 U2OS 24 843 Metaphase +0.16810656265462579 4.70271820856917e-09 BR00117024 PP-2 final compound J10 U2OS 24 697 Metaphase +0.1911862619985574 4.730681687228824e-09 BR00116995 PP-121 final compound B16 U2OS 24 538 Metaphase +0.18470846141599206 4.7904370575474546e-09 BR00117024 BMS-536924 final compound B15 U2OS 24 571 Metaphase +0.2632144197300829 4.969944995846707e-09 BR00116995 buparlisib final compound L12 U2OS 24 279 Metaphase +0.18006139952829925 5.357384894081849e-09 BR00116995 BMS-536924 final compound B15 U2OS 24 597 Metaphase +0.23596992845463746 8.227730175946318e-09 BR00117024 homoharringtonine final compound N15 U2OS 24 343 Metaphase +0.26521276750724765 1.2501969717437474e-08 BR00117026 NSC-632839 final compound M16 U2OS 24 263 Metaphase +0.23400958016342632 1.4540697204764102e-08 BR00117025 RGB-286638 final compound K21 U2OS 24 336 Metaphase +0.23971021415492397 1.7161521625780736e-08 BR00117026 GK921 final compound H24 U2OS 24 316 Metaphase +0.23014871602983022 2.2364692645563193e-08 BR00117024 PHA-793887 final compound E13 U2OS 24 341 Metaphase +0.23398922639533143 2.32202295890161e-08 BR00117024 TG-101348 final compound M20 U2OS 24 328 Metaphase +0.20083135990325993 2.4716275137434358e-08 BR00116995 fludarabine-phosphate final compound N12 U2OS 24 445 Metaphase 0.6635934819897084 7.119888751228951e-56 BR00117024 SU3327 final compound I20 U2OS 24 265 MetaphaseAlignment 0.5968885541386385 8.714704601045787e-47 BR00117026 SU3327 final compound I20 U2OS 24 278 MetaphaseAlignment 0.5897269097820125 5.418421592396735e-46 BR00116995 SU3327 final compound I20 U2OS 24 281 MetaphaseAlignment @@ -409,6 +4009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5031055900621118 1.9913891041084745e-37 BR00117026 thiostrepton final compound B02 U2OS 24 322 MetaphaseAlignment 0.5646987608602763 2.8542219313980477e-35 BR00117025 AZD7762 final compound I05 U2OS 24 236 MetaphaseAlignment 0.5059696923312413 3.900042512897267e-33 BR00117024 delanzomib final compound L11 U2OS 24 282 MetaphaseAlignment +0.585 4.8365256663149875e-32 BR00117024 AZD7762 final compound I05 U2OS 24 200 MetaphaseAlignment +0.49942514906018554 8.608030491719336e-32 BR00117025 puromycin final compound C22 U2OS 24 274 MetaphaseAlignment +0.5708746779583195 2.1250745943489465e-30 BR00117026 ponatinib final compound C20 U2OS 24 199 MetaphaseAlignment +0.5643564356435643 5.376368463724474e-30 BR00117026 AZD7762 final compound I05 U2OS 24 202 MetaphaseAlignment +0.4675353764262563 7.144658474396486e-28 BR00117024 thiostrepton final compound B02 U2OS 24 277 MetaphaseAlignment +0.4679851867754401 1.7447965822825847e-27 BR00116995 puromycin final compound C22 U2OS 24 272 MetaphaseAlignment +0.4402100097015351 1.8921227294915193e-26 BR00117025 thiostrepton final compound B02 U2OS 24 297 MetaphaseAlignment +0.5036158694246929 3.0764138749987513e-26 BR00117024 puromycin final compound C22 U2OS 24 224 MetaphaseAlignment +0.43486317311820666 1.0638127021494125e-25 BR00116995 briciclib final compound H01 U2OS 24 297 MetaphaseAlignment +0.4468878566688786 2.1440899090419954e-25 BR00117026 AZD7762 final compound K11 U2OS 24 275 MetaphaseAlignment +0.4477109606260898 5.208092444651346e-25 BR00116995 delanzomib final compound L11 U2OS 24 271 MetaphaseAlignment +0.42105263157894735 1.5534051446648148e-24 BR00117026 NSC-663284 final compound G06 U2OS 24 304 MetaphaseAlignment +0.43609557702084395 2.050645741995681e-24 BR00117026 CYT-997 final compound E06 U2OS 24 280 MetaphaseAlignment +0.4982431807674526 5.4035083419080805e-24 BR00117026 colchicine final compound K17 U2OS 24 210 MetaphaseAlignment +0.611965811965812 1.0258321004426462e-23 BR00117026 LDN-212854 final compound K01 U2OS 24 135 MetaphaseAlignment +0.4180964052287582 2.598378694377092e-23 BR00117024 briciclib final compound H01 U2OS 24 289 MetaphaseAlignment +0.45121951219512196 6.206541809688896e-23 BR00117026 CYT-997 final compound C09 U2OS 24 246 MetaphaseAlignment +0.4586411705055773 9.24202091248691e-23 BR00117024 AZD7762 final compound K11 U2OS 24 234 MetaphaseAlignment +0.4365079365079365 5.9605946165637255e-22 BR00116995 colchicine final compound K17 U2OS 24 252 MetaphaseAlignment +0.46515151515151515 6.474238260339918e-22 BR00117024 CYT-997 final compound E06 U2OS 24 220 MetaphaseAlignment +0.45092551127033886 1.268926526257195e-21 BR00117024 ryuvidine final compound A14 U2OS 24 231 MetaphaseAlignment +0.4489603374278526 1.5919936822477788e-21 BR00117024 oxibendazole final compound M19 U2OS 24 232 MetaphaseAlignment +0.45908372827804106 9.384783761347235e-21 BR00116995 thiostrepton final compound B02 U2OS 24 211 MetaphaseAlignment +0.40959748262750756 2.631909778284422e-20 BR00117026 NSC-632839 final compound M16 U2OS 24 263 MetaphaseAlignment +0.4331450094161959 2.9066687139003773e-20 BR00117024 colchicine final compound K17 U2OS 24 234 MetaphaseAlignment +0.5121951219512195 5.814500348544026e-20 BR00117024 ponatinib final compound C20 U2OS 24 164 MetaphaseAlignment +0.388020522610667 6.938489740153209e-20 BR00116995 NSC-632839 final compound M16 U2OS 24 289 MetaphaseAlignment +0.4174713787954206 1.143254280523852e-19 BR00117025 colchicine final compound K17 U2OS 24 245 MetaphaseAlignment +0.5645591085271318 1.3688475106227444e-19 BR00117024 LDN-212854 final compound K01 U2OS 24 129 MetaphaseAlignment +0.403518837253777 9.082472253418973e-19 BR00117024 CYT-997 final compound C09 U2OS 24 249 MetaphaseAlignment +0.3998299319727891 6.98452877500452e-18 BR00117024 NSC-632839 final compound M16 U2OS 24 240 MetaphaseAlignment +0.3629900803023146 1.487638708795356e-17 BR00117025 CYT-997 final compound C09 U2OS 24 290 MetaphaseAlignment +0.3929733595565886 6.957057853448958e-17 BR00117025 ponatinib final compound C20 U2OS 24 235 MetaphaseAlignment +0.543939393939394 3.884410872283738e-16 BR00117025 LDN-212854 final compound K01 U2OS 24 110 MetaphaseAlignment +0.3597437341593917 6.515422110795501e-16 BR00117025 briciclib final compound H01 U2OS 24 268 MetaphaseAlignment +0.35371726274288934 2.7360956513932333e-15 BR00117026 oxibendazole final compound M19 U2OS 24 268 MetaphaseAlignment +0.3482169171824344 1.174815368401723e-14 BR00117026 briciclib final compound H01 U2OS 24 261 MetaphaseAlignment +0.35517264079523386 2.0313385238413418e-14 BR00117025 AZD7762 final compound K11 U2OS 24 247 MetaphaseAlignment +0.4110016814797021 2.3228956844026697e-14 BR00116995 ponatinib final compound C20 U2OS 24 181 MetaphaseAlignment +0.40019157088122603 3.356410951054215e-13 BR00117026 ryuvidine final compound A14 U2OS 24 174 MetaphaseAlignment +0.307280701754386 4.304523345494101e-13 BR00117025 NSC-663284 final compound G06 U2OS 24 304 MetaphaseAlignment +0.19310344827586207 3.120851192221377e-12 BR00116995 RKI-1447 final compound J04 U2OS 24 725 MetaphaseAlignment +0.18977119784656796 4.144556183578874e-12 BR00117024 RKI-1447 final compound J04 U2OS 24 743 MetaphaseAlignment +0.17709149662825685 2.872534999030755e-11 BR00117026 RKI-1447 final compound J04 U2OS 24 786 MetaphaseAlignment +0.2921895486046076 3.6959482358178316e-11 BR00117024 NSC-663284 final compound G06 U2OS 24 285 MetaphaseAlignment +0.17001180637544275 4.200571573378392e-11 BR00117025 RKI-1447 final compound J04 U2OS 24 847 MetaphaseAlignment +0.353964953964954 9.075168904695953e-11 BR00117025 CYT-997 final compound E06 U2OS 24 182 MetaphaseAlignment +0.26495605901797953 2.9617062683304177e-10 BR00116995 7-hydroxystaurosporine final compound L04 U2OS 24 316 MetaphaseAlignment +0.2521489971346705 3.7485906281301124e-10 BR00117026 UNC1999 final compound H19 U2OS 24 349 MetaphaseAlignment +0.3018083878414775 1.1200754132740313e-09 BR00117026 buparlisib final compound L12 U2OS 24 226 MetaphaseAlignment +0.1772400154078862 1.6984008061622911e-09 BR00117024 AZ191 final compound I18 U2OS 24 653 MetaphaseAlignment +0.2120773920491762 2.978820558297257e-09 BR00116995 fludarabine-phosphate final compound N12 U2OS 24 445 MetaphaseAlignment +0.26141639879585693 6.199582010601999e-09 BR00117025 BI-2536 final compound E21 U2OS 24 278 MetaphaseAlignment +0.18148490734745476 1.2302958703022496e-08 BR00116995 UNC1999 final compound H19 U2OS 24 569 MetaphaseAlignment +0.22593600820609935 1.73615670980339e-08 BR00117026 7-hydroxystaurosporine final compound L04 U2OS 24 355 MetaphaseAlignment +0.192 1.796150290481388e-08 BR00117024 fludarabine-phosphate final compound N12 U2OS 24 500 MetaphaseAlignment +0.16416487810247096 2.1427054451092797e-08 BR00117025 BMS-536924 final compound B15 U2OS 24 673 MetaphaseAlignment +0.2534451302356275 2.2612948895045113e-08 BR00116995 buparlisib final compound L12 U2OS 24 279 MetaphaseAlignment +0.2725064709428075 2.3507860472754674e-08 BR00116995 oxibendazole final compound M19 U2OS 24 238 MetaphaseAlignment +0.14811797093934792 3.304580863945228e-08 BR00117026 PP-2 final compound J10 U2OS 24 806 MetaphaseAlignment +0.23426863689191432 3.307175931224944e-08 BR00117024 BI-2536 final compound E21 U2OS 24 317 MetaphaseAlignment +0.15456989247311828 3.592717103142261e-08 BR00117025 PP-2 final compound J10 U2OS 24 744 MetaphaseAlignment +0.20676709708273552 3.831603025840065e-08 BR00117026 epothilone-b final compound F07 U2OS 24 410 MetaphaseAlignment +0.22691047093324132 3.841781930139498e-08 BR00116995 BI-2536 final compound E21 U2OS 24 340 MetaphaseAlignment +0.24161073825503357 4.8286347705080225e-08 BR00117026 BI-2536 final compound E21 U2OS 24 298 MetaphaseAlignment +0.24612599113441969 4.966638770162373e-08 BR00117024 buparlisib final compound L12 U2OS 24 285 MetaphaseAlignment +0.2470534210929129 5.084371810873391e-08 BR00117025 oxibendazole final compound M19 U2OS 24 278 MetaphaseAlignment +0.24816849816849818 6.38059439225419e-08 BR00117024 buparlisib final compound D11 U2OS 24 276 MetaphaseAlignment +0.21461433735505375 9.066194770251335e-08 BR00117024 7-hydroxystaurosporine final compound L04 U2OS 24 358 MetaphaseAlignment +0.22988006617038875 1.0213149661993305e-07 BR00116995 BI-2536 final compound I14 U2OS 24 312 MetaphaseAlignment +0.14430379746835442 1.3682775705806245e-07 BR00116995 AZ191 final compound I18 U2OS 24 790 MetaphaseAlignment +0.2887854609929078 1.694854078652382e-07 BR00117025 ryuvidine final compound A14 U2OS 24 192 MetaphaseAlignment +0.21736725663716813 1.7952833162772206e-07 BR00117026 BI-2536 final compound I14 U2OS 24 339 MetaphaseAlignment +0.22131922944616442 4.7172141976566797e-07 BR00116995 buparlisib final compound D11 U2OS 24 304 MetaphaseAlignment +0.22100196596840893 6.341109719342011e-07 BR00117025 ixabepilone final compound J21 U2OS 24 298 MetaphaseAlignment +0.19895710928319624 6.658142825230913e-07 BR00117026 buparlisib final compound D11 U2OS 24 368 MetaphaseAlignment +0.14447819038923773 8.339509741391975e-07 BR00117024 PP-2 final compound J10 U2OS 24 697 MetaphaseAlignment +0.17112991538078645 9.07549037579449e-07 BR00117024 BAX-channel-blocker final compound I19 U2OS 24 492 MetaphaseAlignment +0.21392659627953745 1.0860751691034078e-06 BR00117024 ixabepilone final compound J21 U2OS 24 306 MetaphaseAlignment +0.2032352111351453 1.109248798207422e-06 BR00116995 epothilone-b final compound F07 U2OS 24 341 MetaphaseAlignment +0.25001993143586065 1.1693761819020023e-06 BR00117025 NSC-632839 final compound M16 U2OS 24 222 MetaphaseAlignment +0.22794117647058823 1.3204240327056107e-06 BR00117025 buparlisib final compound D11 U2OS 24 272 MetaphaseAlignment +0.15033920449933624 1.4696622384393879e-06 BR00116995 WH-4-023 final compound A18 U2OS 24 617 MetaphaseAlignment +0.1951964395334561 1.610608819584281e-06 BR00117024 BI-2536 final compound I14 U2OS 24 362 MetaphaseAlignment +0.1513335910320835 2.0267111499020525e-06 BR00116995 BMS-536924 final compound B15 U2OS 24 597 MetaphaseAlignment +0.20498841488346736 2.1010093114189987e-06 BR00117026 KG-5 final compound C13 U2OS 24 319 MetaphaseAlignment +0.2254936634246979 2.285182504983148e-06 BR00116995 ixabepilone final compound J21 U2OS 24 261 MetaphaseAlignment +0.11760236867707359 2.509242312846309e-06 BR00117025 regorafenib final compound P13 U2OS 24 974 MetaphaseAlignment +0.21823843416370106 2.559987927164651e-06 BR00117026 ixabepilone final compound J21 U2OS 24 280 MetaphaseAlignment +0.14913208663208663 3.0510614539254006e-06 BR00117026 AZ191 final compound I18 U2OS 24 592 MetaphaseAlignment 0.519528816199377 1.4985273943228363e-79 BR00117025 KU-60019 final compound I07 U2OS 24 642 OutOfFocus 0.4541958722741433 2.5236092608451884e-60 BR00117026 KU-60019 final compound I07 U2OS 24 642 OutOfFocus 0.4363185094519244 2.5242358623250367e-59 BR00117024 KU-60019 final compound I07 U2OS 24 688 OutOfFocus @@ -419,6 +4109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.48008837337752003 1.3878446013555196e-37 BR00117026 7-hydroxystaurosporine final compound L04 U2OS 24 355 OutOfFocus 0.5680493473985339 1.1961685778533336e-35 BR00117025 ponatinib final compound C20 U2OS 24 235 OutOfFocus 0.5079628400796284 1.210551411804553e-32 BR00117026 AZD7762 final compound K11 U2OS 24 275 OutOfFocus +0.44617623585747146 1.3720706844396898e-32 BR00117024 7-hydroxystaurosporine final compound L04 U2OS 24 358 OutOfFocus +0.46349673466096913 4.384818215519819e-31 BR00116995 7-hydroxystaurosporine final compound L04 U2OS 24 316 OutOfFocus +0.26099706744868034 4.99674969345896e-31 BR00117025 polydatin final compound K08 U2OS 24 1023 OutOfFocus +0.46381578947368424 6.822113509037355e-30 BR00117026 NSC-663284 final compound G06 U2OS 24 304 OutOfFocus +0.5196653628857019 1.0450568129566454e-29 BR00117024 AZD7762 final compound K11 U2OS 24 234 OutOfFocus +0.2549158967069415 2.880593566700226e-29 BR00117024 polydatin final compound K08 U2OS 24 1005 OutOfFocus +0.4506578947368421 3.1680083086736128e-28 BR00117025 NSC-663284 final compound G06 U2OS 24 304 OutOfFocus +0.4655968226706741 2.0197502914524366e-27 BR00116995 puromycin final compound C22 U2OS 24 272 OutOfFocus +0.5359538810805295 8.602775969504892e-27 BR00117026 ponatinib final compound C20 U2OS 24 199 OutOfFocus +0.4774248682523857 3.606581137216179e-25 BR00117025 AZD7762 final compound I05 U2OS 24 236 OutOfFocus +0.43451196489616817 2.929023599045073e-24 BR00117024 delanzomib final compound L11 U2OS 24 282 OutOfFocus +0.504950495049505 8.574440288793307e-24 BR00117026 AZD7762 final compound I05 U2OS 24 202 OutOfFocus +0.34232377689323323 1.1278527281822914e-23 BR00116995 fludarabine-phosphate final compound N12 U2OS 24 445 OutOfFocus +0.33405639913232105 3.542257992762124e-23 BR00117026 AVL-292 final compound A24 U2OS 24 461 OutOfFocus +0.37293572234055883 5.540677230816516e-22 BR00117025 7-hydroxystaurosporine final compound L04 U2OS 24 345 OutOfFocus +0.45152261531571874 7.066706016336912e-22 BR00117024 ryuvidine final compound A14 U2OS 24 231 OutOfFocus +0.5304878048780488 1.8344716503100934e-21 BR00117024 ponatinib final compound C20 U2OS 24 164 OutOfFocus +0.48 3.1330954373417528e-21 BR00117024 AZD7762 final compound I05 U2OS 24 200 OutOfFocus +0.41749571183533446 4.482623343355891e-21 BR00117024 SU3327 final compound I20 U2OS 24 265 OutOfFocus +0.39434256956094177 6.9574884466289e-21 BR00117025 delanzomib final compound L11 U2OS 24 295 OutOfFocus +0.4919529185683401 1.0037336201694671e-20 BR00116995 ponatinib final compound C20 U2OS 24 181 OutOfFocus +0.3997627520759193 1.8272369918607592e-20 BR00116995 SU3327 final compound I20 U2OS 24 281 OutOfFocus +0.4942528735632184 3.3192436309114957e-20 BR00117026 ryuvidine final compound A14 U2OS 24 174 OutOfFocus +0.47717198581560283 4.2358294030528515e-20 BR00117025 ryuvidine final compound A14 U2OS 24 192 OutOfFocus +0.3264705882352941 8.009289394638833e-20 BR00117026 epothilone-b final compound F07 U2OS 24 410 OutOfFocus +0.32714502706843057 4.472015619193985e-19 BR00117025 PP-121 final compound B16 U2OS 24 391 OutOfFocus +0.2755705668858091 4.891652579411247e-19 BR00117026 PF-431396 final compound L20 U2OS 24 556 OutOfFocus +0.4205085597248522 1.1689557142106425e-18 BR00117025 SU3327 final compound I20 U2OS 24 226 OutOfFocus +0.2625901625405643 1.6934703666438635e-18 BR00117026 BMS-536924 final compound B15 U2OS 24 593 OutOfFocus +0.284 3.644777735190423e-18 BR00117024 fludarabine-phosphate final compound N12 U2OS 24 500 OutOfFocus +0.24184029497551043 8.470845801302554e-18 BR00117025 BMS-536924 final compound B15 U2OS 24 673 OutOfFocus +0.30089430628628694 1.183799402169639e-17 BR00117025 AVL-292 final compound A24 U2OS 24 431 OutOfFocus +0.4143705559146736 1.32217784728821e-17 BR00117024 puromycin final compound C22 U2OS 24 224 OutOfFocus +0.332378223495702 1.815601580706301e-17 BR00117026 UNC1999 final compound H19 U2OS 24 349 OutOfFocus +0.26233201581027665 3.5387750597921115e-17 BR00117025 PF-431396 final compound L20 U2OS 24 550 OutOfFocus +0.2711676451402479 5.933023683865719e-17 BR00117025 fludarabine-phosphate final compound N12 U2OS 24 510 OutOfFocus +0.357457701192483 1.2441887023911643e-16 BR00117024 NSC-663284 final compound G06 U2OS 24 285 OutOfFocus +0.36198478040672155 1.308939386888848e-16 BR00117026 SU3327 final compound I20 U2OS 24 278 OutOfFocus +0.36934820068070806 1.3714682550066236e-16 BR00117026 delanzomib final compound L11 U2OS 24 267 OutOfFocus +0.38290816326530613 2.0556664756232866e-16 BR00117024 NSC-632839 final compound M16 U2OS 24 240 OutOfFocus +0.26040384141836986 3.276467460445968e-16 BR00117026 fludarabine-phosphate final compound N12 U2OS 24 527 OutOfFocus +0.39400462409311965 4.0729901152557274e-16 BR00117025 NSC-632839 final compound M16 U2OS 24 222 OutOfFocus +0.29855525185474424 6.094990624429383e-16 BR00117025 epothilone-b final compound F07 U2OS 24 390 OutOfFocus +0.3039549465202712 7.752618223221588e-16 BR00117024 epothilone-b final compound F07 U2OS 24 372 OutOfFocus +0.19951540849549482 3.411473055965259e-15 BR00116995 BAN-ORL-24 final compound A15 U2OS 24 846 OutOfFocus +0.49202279202279203 4.316741668734288e-15 BR00117026 LDN-212854 final compound K01 U2OS 24 135 OutOfFocus +0.2313915857605178 6.479470953328234e-15 BR00117026 BAN-ORL-24 final compound A15 U2OS 24 618 OutOfFocus +0.3369304556354916 1.194046487702707e-14 BR00117025 TG-101348 final compound M20 U2OS 24 278 OutOfFocus +0.20833333333333334 1.5251677669626185e-14 BR00117025 PP-2 final compound J10 U2OS 24 744 OutOfFocus +0.3092174173275475 2.154175114036407e-14 BR00117024 TG-101348 final compound M20 U2OS 24 328 OutOfFocus +0.285048499032725 2.6248799128311114e-14 BR00116995 AVL-292 final compound A24 U2OS 24 383 OutOfFocus +0.5121212121212121 2.8651037729574694e-14 BR00117025 LDN-212854 final compound K01 U2OS 24 110 OutOfFocus +0.24236641221374045 6.490840397994936e-14 BR00117024 AVL-292 final compound A24 U2OS 24 524 OutOfFocus +0.229706390328152 7.87645800347431e-14 BR00117025 BAN-ORL-24 final compound A15 U2OS 24 579 OutOfFocus +0.4780765503875969 1.0112040069664653e-13 BR00117024 LDN-212854 final compound K01 U2OS 24 129 OutOfFocus +0.19148546811625508 1.5855341769649898e-13 BR00117025 arcyriaflavin-a final compound B04 U2OS 24 817 OutOfFocus +0.23158602896299174 3.6387457746399617e-13 BR00116995 PP-121 final compound B16 U2OS 24 538 OutOfFocus +0.35513468013468014 9.111284773985807e-13 BR00117024 CYT-997 final compound E06 U2OS 24 220 OutOfFocus +0.3244322072170505 1.011630108738577e-12 BR00117026 NSC-632839 final compound M16 U2OS 24 263 OutOfFocus +0.22848434645936877 1.3012187577869816e-12 BR00117024 JTE-607 final compound C14 U2OS 24 532 OutOfFocus +0.3056437179334208 1.9674541630580343e-12 BR00116995 NSC-632839 final compound M16 U2OS 24 289 OutOfFocus +0.2597402597402597 2.880458294896844e-12 BR00117024 PP-121 final compound B16 U2OS 24 399 OutOfFocus +0.26221551225431405 6.696440931077058e-12 BR00117026 PP-121 final compound B16 U2OS 24 374 OutOfFocus +0.2083494395052184 7.786218240803066e-12 BR00116995 BMS-536924 final compound B15 U2OS 24 597 OutOfFocus +0.22549019607843138 8.97573495390077e-12 BR00117026 ganetespib final compound M10 U2OS 24 510 OutOfFocus +0.17810142834216017 1.1521417330306301e-11 BR00117026 PP-2 final compound J10 U2OS 24 806 OutOfFocus +0.16999513241877653 2.7010769824175424e-11 BR00117025 lonafarnib final compound J06 U2OS 24 853 OutOfFocus +0.2607796536930152 2.918229883836099e-11 BR00117025 UNC1999 final compound H19 U2OS 24 362 OutOfFocus +0.2277205553067622 4.789346536015146e-11 BR00117026 UNC2025 final compound N06 U2OS 24 464 OutOfFocus +0.2353572323344553 6.397719451563894e-11 BR00117025 ganetespib final compound I17 U2OS 24 431 OutOfFocus +0.2177315321893635 8.47761394183966e-11 BR00116995 PF-431396 final compound L20 U2OS 24 498 OutOfFocus +0.19457063334755959 9.169204691765039e-11 BR00116995 WH-4-023 final compound A18 U2OS 24 617 OutOfFocus +0.23397358668089452 1.3371152907276332e-10 BR00117025 UNC2025 final compound N06 U2OS 24 418 OutOfFocus +0.2843469096770194 1.3801464030540812e-10 BR00117026 TG-101348 final compound M20 U2OS 24 283 OutOfFocus +0.17551302216019435 2.1324926279169628e-10 BR00117025 lonafarnib final compound F22 U2OS 24 734 OutOfFocus +0.18000208528829112 2.711136412056923e-10 BR00117026 JTE-607 final compound C14 U2OS 24 695 OutOfFocus +0.22321428571428573 3.4347666367046833e-10 BR00117025 ganetespib final compound M10 U2OS 24 448 OutOfFocus +0.17988420748863718 6.771884733788229e-10 BR00117026 lonafarnib final compound F22 U2OS 24 664 OutOfFocus +0.1594867583370184 7.735997416251535e-10 BR00117026 SB-203580 final compound L08 U2OS 24 843 OutOfFocus +0.18850036584808158 1.1300303119018861e-09 BR00116995 ganetespib final compound I17 U2OS 24 592 OutOfFocus +0.2227071258097511 1.4446083809071198e-09 BR00117026 ganetespib final compound I17 U2OS 24 419 OutOfFocus +0.15318005760767828 1.7566586641603099e-09 BR00117025 SB-203580 final compound L08 U2OS 24 883 OutOfFocus +0.2724544827865861 1.950076654026882e-09 BR00116995 delanzomib final compound L11 U2OS 24 271 OutOfFocus +0.19089878659223733 2.844134630905739e-09 BR00117026 WH-4-023 final compound A18 U2OS 24 552 OutOfFocus +0.231353591160221 5.589672915631591e-09 BR00117024 BI-2536 final compound I14 U2OS 24 362 OutOfFocus +0.1669948097494726 6.006862081910839e-09 BR00117024 PP-2 final compound J10 U2OS 24 697 OutOfFocus +0.14370660068640753 6.466904716615524e-09 BR00117024 lonafarnib final compound J06 U2OS 24 935 OutOfFocus +0.19305617311397658 6.488507133237773e-09 BR00117024 PF-431396 final compound L20 U2OS 24 519 OutOfFocus +0.1606829064115841 6.991906768834115e-09 BR00117026 nafamostat final compound I08 U2OS 24 746 OutOfFocus +0.1597334745105589 8.099380135015463e-09 BR00117026 arcyriaflavin-a final compound B04 U2OS 24 751 OutOfFocus 0.6147941680960549 1.4949281300477887e-47 BR00117024 SU3327 final compound I20 U2OS 24 265 Polylobed 0.4139370729628147 4.0155713105802834e-43 BR00117026 PF-431396 final compound L20 U2OS 24 556 Polylobed 0.4309602044541804 5.573218351459969e-42 BR00116995 PF-431396 final compound L20 U2OS 24 498 Polylobed @@ -429,6 +4209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5027611417904644 6.287177824489772e-35 BR00117026 puromycin final compound C22 U2OS 24 299 Polylobed 0.605 2.0470461494164774e-34 BR00117024 AZD7762 final compound I05 U2OS 24 200 Polylobed 0.4997662519803652 2.988800701999435e-32 BR00117026 SU3327 final compound I20 U2OS 24 278 Polylobed +0.36584276817468825 7.223155240049638e-31 BR00117025 danusertib final compound N18 U2OS 24 508 Polylobed +0.3564894225271584 2.225370955235596e-30 BR00117025 AMG900 final compound N09 U2OS 24 528 Polylobed +0.4953931160194244 3.309401386316684e-30 BR00117026 delanzomib final compound L11 U2OS 24 267 Polylobed +0.5283456351199908 1.5440495534900098e-29 BR00117025 SU3327 final compound I20 U2OS 24 226 Polylobed +0.367983367983368 2.3440011551224935e-29 BR00117024 danusertib final compound E05 U2OS 24 481 Polylobed +0.5139794292336666 9.2826558704767e-29 BR00117024 AZD7762 final compound K11 U2OS 24 234 Polylobed +0.4769391192748857 1.4549500392470474e-28 BR00117025 puromycin final compound C22 U2OS 24 274 Polylobed +0.46834781055880814 1.8150258199008227e-28 BR00116995 SU3327 final compound I20 U2OS 24 281 Polylobed +0.35897951657782695 2.1227108374127266e-28 BR00117026 danusertib final compound E05 U2OS 24 488 Polylobed +0.4554752125874935 6.122239613435491e-28 BR00117025 delanzomib final compound L11 U2OS 24 295 Polylobed +0.46900493774151997 9.816227628357943e-28 BR00116995 puromycin final compound C22 U2OS 24 272 Polylobed +0.4985757014670275 1.63867779411912e-27 BR00117025 AZD7762 final compound I05 U2OS 24 236 Polylobed +0.3724175035868006 7.298685451173123e-26 BR00117026 epothilone-b final compound F07 U2OS 24 410 Polylobed +0.3881819729338667 8.383551059735625e-26 BR00117024 epothilone-b final compound F07 U2OS 24 372 Polylobed +0.33736916855130594 2.600567432345477e-25 BR00116995 AMG900 final compound N09 U2OS 24 491 Polylobed +0.34609643230332887 3.174584994467062e-25 BR00117026 UNC2025 final compound N06 U2OS 24 464 Polylobed +0.37550436027593387 3.254030186148543e-25 BR00117025 epothilone-b final compound F07 U2OS 24 390 Polylobed +0.40993788819875776 1.3601153070073755e-24 BR00117026 thiostrepton final compound B02 U2OS 24 322 Polylobed +0.27052489905787347 2.5452286524580355e-24 BR00117024 RKI-1447 final compound J04 U2OS 24 743 Polylobed +0.5099009900990099 2.8112918979650187e-24 BR00117026 AZD7762 final compound I05 U2OS 24 202 Polylobed +0.5058541438155243 8.52870578733945e-24 BR00117026 ponatinib final compound C20 U2OS 24 199 Polylobed +0.3253012048192771 1.0392768636834217e-23 BR00117025 danusertib final compound E05 U2OS 24 498 Polylobed +0.34601339174827317 1.2240378365881585e-23 BR00117024 AMG900 final compound N09 U2OS 24 433 Polylobed +0.27263203877264136 2.9718341638604935e-23 BR00117024 PP-2 final compound J10 U2OS 24 697 Polylobed +0.47224466709760826 5.469908549248071e-23 BR00117024 puromycin final compound C22 U2OS 24 224 Polylobed +0.3240809944760874 7.515187269130007e-23 BR00117024 danusertib final compound N18 U2OS 24 482 Polylobed +0.41766581464597224 4.49813976743604e-22 BR00117024 thiostrepton final compound B02 U2OS 24 277 Polylobed +0.41729263437292635 4.540453058655251e-22 BR00117026 AZD7762 final compound K11 U2OS 24 275 Polylobed +0.3102766798418972 6.512916302194967e-22 BR00117026 danusertib final compound N18 U2OS 24 506 Polylobed +0.41390589730073124 2.1118756093205446e-21 BR00116995 delanzomib final compound L11 U2OS 24 271 Polylobed +0.2803622348083786 3.2425880036819915e-21 BR00116995 BMS-536924 final compound B15 U2OS 24 597 Polylobed +0.4465591879384983 3.336716509040444e-21 BR00117024 ryuvidine final compound A14 U2OS 24 231 Polylobed +0.27466007546023674 5.555460905609919e-21 BR00116995 WH-4-023 final compound A18 U2OS 24 617 Polylobed +0.524390243902439 5.9032356952286335e-21 BR00117024 ponatinib final compound C20 U2OS 24 164 Polylobed +0.26136811402784654 8.061309997942351e-21 BR00117025 BMS-536924 final compound B15 U2OS 24 673 Polylobed +0.32989111103461727 9.763131071970868e-21 BR00117025 UNC2025 final compound N06 U2OS 24 418 Polylobed +0.3898647491867831 1.1393239446381163e-20 BR00117025 thiostrepton final compound B02 U2OS 24 297 Polylobed +0.3867543859649123 1.2251203747265624e-20 BR00117025 NSC-663284 final compound G06 U2OS 24 304 Polylobed +0.4281462585034014 1.5301184901633906e-20 BR00117024 NSC-632839 final compound M16 U2OS 24 240 Polylobed +0.3920773177425128 2.1147783812376345e-20 BR00116995 NSC-632839 final compound M16 U2OS 24 289 Polylobed +0.5727955426356589 2.6206954336204556e-20 BR00117024 LDN-212854 final compound K01 U2OS 24 129 Polylobed +0.32369700748129676 3.294524324818823e-19 BR00117024 GSK1070916 final compound C04 U2OS 24 401 Polylobed +0.30734966592427615 3.987751397647919e-19 BR00117026 GSK1070916 final compound C04 U2OS 24 449 Polylobed +0.3495036892008584 4.463755789897875e-19 BR00116995 epothilone-b final compound F07 U2OS 24 341 Polylobed +0.5501424501424501 4.811586256937223e-19 BR00117026 LDN-212854 final compound K01 U2OS 24 135 Polylobed +0.22618298087725147 1.3859457514396578e-18 BR00117026 PP-2 final compound J10 U2OS 24 806 Polylobed +0.23521505376344087 1.8538598300719524e-18 BR00117025 PP-2 final compound J10 U2OS 24 744 Polylobed +0.3651315789473684 2.0733962547876034e-18 BR00117026 NSC-663284 final compound G06 U2OS 24 304 Polylobed +0.2575424773619397 8.348477208721412e-18 BR00117026 BMS-536924 final compound B15 U2OS 24 593 Polylobed +0.24355543293327817 9.238669602607861e-18 BR00116995 PP-2 final compound J10 U2OS 24 660 Polylobed +0.24789232866043615 9.429008842422215e-18 BR00117025 KU-60019 final compound I07 U2OS 24 642 Polylobed +0.29652012665354677 1.3308304485578725e-17 BR00116995 danusertib final compound N18 U2OS 24 439 Polylobed +0.3342918487846024 1.7192787725636786e-16 BR00117024 UNC2025 final compound N06 U2OS 24 322 Polylobed +0.38726980153763635 2.1416802919585018e-16 BR00117025 ponatinib final compound C20 U2OS 24 235 Polylobed +0.23719334112149532 2.434801196020521e-16 BR00117026 KU-60019 final compound I07 U2OS 24 642 Polylobed +0.37895395148283467 3.3770091108724377e-16 BR00117025 AZD7762 final compound K11 U2OS 24 247 Polylobed +0.3468988307066599 1.9916637053389895e-15 BR00117026 CYT-997 final compound E06 U2OS 24 280 Polylobed +0.3611111111111111 5.399465923528127e-15 BR00116995 colchicine final compound K17 U2OS 24 252 Polylobed +0.19834710743801653 5.516066316452419e-15 BR00117025 RKI-1447 final compound J04 U2OS 24 847 Polylobed +0.2934615438883637 8.177789530186605e-15 BR00117026 PP-121 final compound B16 U2OS 24 374 Polylobed +0.2640101857964727 1.0551015230267624e-14 BR00117025 WH-4-023 final compound A18 U2OS 24 460 Polylobed +0.2764956435349602 1.1130976165285111e-14 BR00117025 GSK1070916 final compound C04 U2OS 24 419 Polylobed +0.2646420824295011 1.3383603566185616e-14 BR00117026 AVL-292 final compound A24 U2OS 24 461 Polylobed +0.3542742398164085 1.4716640164520664e-14 BR00117024 CYT-997 final compound C09 U2OS 24 249 Polylobed +0.38013468013468016 1.5156939156498294e-14 BR00117024 CYT-997 final compound E06 U2OS 24 220 Polylobed +0.31538782753940914 3.033217583966282e-14 BR00116995 UNC2025 final compound N06 U2OS 24 310 Polylobed +0.21543265238332504 3.748901583527279e-14 BR00117026 PP-1 final compound A22 U2OS 24 669 Polylobed +0.4081791976939707 3.907401891013688e-14 BR00116995 ponatinib final compound C20 U2OS 24 181 Polylobed +0.18831738004002543 4.0016558530389346e-14 BR00117025 SB-203580 final compound L08 U2OS 24 883 Polylobed +0.3249591503267974 4.28047453369805e-14 BR00117024 briciclib final compound H01 U2OS 24 289 Polylobed +0.20551724137931035 8.24448619357476e-14 BR00116995 RKI-1447 final compound J04 U2OS 24 725 Polylobed +0.5 1.3568831368700863e-13 BR00117025 LDN-212854 final compound K01 U2OS 24 110 Polylobed +0.32080914028844354 2.2016568707407488e-13 BR00117024 NSC-663284 final compound G06 U2OS 24 285 Polylobed +0.32939993881386304 3.4856231528571424e-13 BR00117026 NSC-632839 final compound M16 U2OS 24 263 Polylobed +0.3471316818774446 4.358452865059246e-13 BR00117024 colchicine final compound K17 U2OS 24 234 Polylobed +0.204499864001088 4.58493189113658e-13 BR00117024 KU-60019 final compound I07 U2OS 24 688 Polylobed +0.1846925954782511 4.886992827125219e-13 BR00117026 SB-203580 final compound L08 U2OS 24 843 Polylobed +0.22714377440574468 5.479380373446067e-13 BR00117026 WH-4-023 final compound A18 U2OS 24 552 Polylobed +0.22295567829718443 6.887335232170609e-13 BR00117024 BMS-536924 final compound B15 U2OS 24 571 Polylobed +0.30109351432880843 6.966802832651249e-13 BR00117024 ixabepilone final compound J21 U2OS 24 306 Polylobed +0.3333333333333333 1.6812424806125408e-12 BR00117026 CYT-997 final compound C09 U2OS 24 246 Polylobed +0.3313257010121122 2.2376251645831543e-12 BR00117025 colchicine final compound K17 U2OS 24 245 Polylobed +0.16226783968719452 3.602296224865975e-12 BR00117025 polydatin final compound K08 U2OS 24 1023 Polylobed +0.16927017306626851 4.564645448711101e-12 BR00117024 SB-203580 final compound L08 U2OS 24 924 Polylobed +0.22745098039215686 5.663602726502882e-12 BR00117026 ganetespib final compound M10 U2OS 24 510 Polylobed +0.2973783656117147 7.11356280658856e-12 BR00117025 CYT-997 final compound C09 U2OS 24 290 Polylobed +0.1672290510382525 7.851290647633956e-12 BR00117024 AC-710 final compound I03 U2OS 24 931 Polylobed +0.18100020317534032 9.163231379163608e-12 BR00117026 RKI-1447 final compound J04 U2OS 24 786 Polylobed +0.37126436781609196 2.1725776491730818e-11 BR00117026 ryuvidine final compound A14 U2OS 24 174 Polylobed +0.21730609423375324 3.139400312633522e-11 BR00117024 WH-4-023 final compound A18 U2OS 24 521 Polylobed 0.33 1.6968714178670592e-24 BR00117024 fludarabine-phosphate final compound N12 U2OS 24 500 Prometaphase 0.40157507276151344 8.80854712339545e-22 BR00117025 thiostrepton final compound B02 U2OS 24 297 Prometaphase 0.3416149068322981 4.7309308005495036e-17 BR00117026 thiostrepton final compound B02 U2OS 24 322 Prometaphase @@ -439,6 +4309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2543092834277272 1.797308855510326e-15 BR00117026 fludarabine-phosphate final compound N12 U2OS 24 527 Prometaphase 0.3424405923544943 5.060372042312558e-15 BR00116995 SU3327 final compound I20 U2OS 24 281 Prometaphase 0.3406228086123159 7.867361535349692e-15 BR00117026 SU3327 final compound I20 U2OS 24 278 Prometaphase +0.35841836734693877 2.174894207108994e-14 BR00117024 NSC-632839 final compound M16 U2OS 24 240 Prometaphase +0.34838227974116476 8.6632853829805e-14 BR00117025 colchicine final compound K17 U2OS 24 245 Prometaphase +0.21106792891546255 1.337465824782939e-13 BR00117026 PP-1 final compound A22 U2OS 24 669 Prometaphase +0.33259035881298893 1.949946638811656e-13 BR00117026 NSC-632839 final compound M16 U2OS 24 263 Prometaphase +0.2168605722221435 1.0859546472045424e-12 BR00117026 BMS-536924 final compound B15 U2OS 24 593 Prometaphase +0.23671211223078442 2.512295254568298e-12 BR00117024 danusertib final compound N18 U2OS 24 482 Prometaphase +0.33378436120210797 2.7946492680041163e-12 BR00117025 AZD7762 final compound I05 U2OS 24 236 Prometaphase +0.19636951756719373 4.0776592669434715e-12 BR00117026 NVS-PAK1-1 final compound N14 U2OS 24 686 Prometaphase +0.2992914501653283 4.585789980260875e-12 BR00117025 CYT-997 final compound C09 U2OS 24 290 Prometaphase +0.19457746143542412 5.179513277268944e-12 BR00117024 PP-2 final compound J10 U2OS 24 697 Prometaphase +0.302783460417829 5.293020498863538e-12 BR00117026 TG-101348 final compound M20 U2OS 24 283 Prometaphase +0.28678923046011656 6.359449590606161e-12 BR00117026 homoharringtonine final compound N15 U2OS 24 315 Prometaphase +0.3013980681240468 8.184646581261826e-12 BR00117026 CYT-997 final compound E06 U2OS 24 280 Prometaphase +0.17894090342333 9.260735354896245e-12 BR00117026 PP-2 final compound J10 U2OS 24 806 Prometaphase +0.20669680621614203 1.1521587529120667e-11 BR00116995 BMS-536924 final compound B15 U2OS 24 597 Prometaphase +0.18548387096774194 1.3410798012444447e-11 BR00117025 PP-2 final compound J10 U2OS 24 744 Prometaphase +0.29514377759217275 1.4081782365884672e-11 BR00116995 NSC-632839 final compound M16 U2OS 24 289 Prometaphase +0.27907474834011564 1.7167083225989133e-11 BR00117026 KG-5 final compound C13 U2OS 24 319 Prometaphase +0.3024451374944817 3.090998900271788e-11 BR00117026 delanzomib final compound L11 U2OS 24 267 Prometaphase +0.2895400807381776 3.276769010805151e-11 BR00117024 briciclib final compound H01 U2OS 24 289 Prometaphase +0.3015770205575894 3.441089869567716e-11 BR00117025 briciclib final compound H01 U2OS 24 268 Prometaphase +0.22088353413654618 4.70136414875683e-11 BR00117025 danusertib final compound E05 U2OS 24 498 Prometaphase +0.2861880708199398 1.2344606932571829e-10 BR00117025 TG-101348 final compound M20 U2OS 24 278 Prometaphase +0.2865912557193696 1.3629731065963791e-10 BR00117026 ixabepilone final compound J21 U2OS 24 280 Prometaphase +0.20468290517671864 2.577638672941399e-10 BR00116995 PP-121 final compound B16 U2OS 24 538 Prometaphase +0.2561099047503698 2.614281143214299e-10 BR00117024 anisomycin final compound N03 U2OS 24 343 Prometaphase +0.2901709401709402 2.854003128809683e-10 BR00117026 briciclib final compound H01 U2OS 24 261 Prometaphase +0.3008130081300813 3.182609689053834e-10 BR00117026 CYT-997 final compound C09 U2OS 24 246 Prometaphase +0.29427232740485754 4.01966637096466e-10 BR00117024 CYT-997 final compound C09 U2OS 24 249 Prometaphase +0.33 4.869254633582969e-10 BR00117024 AZD7762 final compound I05 U2OS 24 200 Prometaphase +0.3061019438111064 5.817436886520971e-10 BR00117025 SU3327 final compound I20 U2OS 24 226 Prometaphase +0.21437901179280489 7.350037196513497e-10 BR00117026 UNC2025 final compound N06 U2OS 24 464 Prometaphase +0.27540809555408097 9.215199805381448e-10 BR00117026 AZD7762 final compound K11 U2OS 24 275 Prometaphase +0.2354101058246092 1.2384389914343229e-09 BR00117024 epothilone-b final compound F07 U2OS 24 372 Prometaphase +0.2705240063268534 1.6132684737967763e-09 BR00117024 delanzomib final compound L11 U2OS 24 282 Prometaphase +0.1897878828701946 1.830625813839698e-09 BR00117024 BMS-536924 final compound B15 U2OS 24 571 Prometaphase +0.22558289663552822 2.1786450489137284e-09 BR00117024 PP-121 final compound B16 U2OS 24 399 Prometaphase +0.24796124494987282 2.315909602278224e-09 BR00117024 TG-101348 final compound M20 U2OS 24 328 Prometaphase +0.26015185411158565 2.7089190165604237e-09 BR00116995 briciclib final compound H01 U2OS 24 297 Prometaphase +0.2191490826477574 2.8271438755057016e-09 BR00117025 UNC2025 final compound N06 U2OS 24 418 Prometaphase +0.2899101839779806 2.8532653640871507e-09 BR00117024 AZD7762 final compound K11 U2OS 24 234 Prometaphase +0.20374220374220375 3.782461614973736e-09 BR00117024 danusertib final compound E05 U2OS 24 481 Prometaphase +0.15301508419493637 3.998246366212736e-09 BR00117026 sotrastaurin final compound K12 U2OS 24 843 Prometaphase +0.29474607350713544 4.199946257512615e-09 BR00117025 NSC-632839 final compound M16 U2OS 24 222 Prometaphase +0.3021214172872941 4.339006211990986e-09 BR00116995 thiostrepton final compound B02 U2OS 24 211 Prometaphase +0.2532467532467532 4.3908288991970346e-09 BR00116995 TG-101348 final compound M20 U2OS 24 308 Prometaphase +0.1676781685102636 9.262816944737237e-09 BR00117025 BMS-536924 final compound B15 U2OS 24 673 Prometaphase +0.20613462564937296 1.3945773082534837e-08 BR00117024 AMG900 final compound N09 U2OS 24 433 Prometaphase +0.25669159360495103 1.4308802036104926e-08 BR00117025 KG-5 final compound C13 U2OS 24 277 Prometaphase +0.2537629470891372 1.9637007610524422e-08 BR00117025 oxibendazole final compound M19 U2OS 24 278 Prometaphase +0.2094332855093257 2.498161752906283e-08 BR00117026 epothilone-b final compound F07 U2OS 24 410 Prometaphase +0.22996863416025093 2.795426773750701e-08 BR00117025 anisomycin final compound N03 U2OS 24 334 Prometaphase +0.2839225589225589 2.9727534542279983e-08 BR00117024 CYT-997 final compound E06 U2OS 24 220 Prometaphase +0.24479666801642852 3.141316198826455e-08 BR00117025 delanzomib final compound L11 U2OS 24 295 Prometaphase +0.2275263645093476 3.2267426473022595e-08 BR00117024 homoharringtonine final compound N15 U2OS 24 343 Prometaphase +0.14361766535123205 4.080748538645591e-08 BR00117026 AC-710 final compound I03 U2OS 24 853 Prometaphase +0.18486465079439035 4.188221365497505e-08 BR00117025 danusertib final compound N18 U2OS 24 508 Prometaphase +0.18871316504073218 4.531394074126324e-08 BR00117026 danusertib final compound E05 U2OS 24 488 Prometaphase +0.2503943744819657 5.080854790349619e-08 BR00117025 puromycin final compound C22 U2OS 24 274 Prometaphase +0.2190318380873476 5.662567622020352e-08 BR00117026 7-hydroxystaurosporine final compound L04 U2OS 24 355 Prometaphase +0.21205388140536036 5.987684621730872e-08 BR00117025 homoharringtonine final compound N15 U2OS 24 380 Prometaphase +0.2133813160987074 7.9686030441873e-08 BR00117026 buparlisib final compound D11 U2OS 24 368 Prometaphase +0.23609151212791255 8.342311998870381e-08 BR00117026 puromycin final compound C22 U2OS 24 299 Prometaphase +0.17439788243310533 8.82522639910826e-08 BR00117026 WH-4-023 final compound A18 U2OS 24 552 Prometaphase +0.24633001383876482 9.640806402026784e-08 BR00117024 KG-5 final compound C13 U2OS 24 274 Prometaphase +0.2871287128712871 9.646397890993259e-08 BR00117026 AZD7762 final compound I05 U2OS 24 202 Prometaphase +0.17090617580859002 1.0479429585269083e-07 BR00116995 UNC1999 final compound H19 U2OS 24 569 Prometaphase +0.27114980607627664 1.078130185409644e-07 BR00117024 puromycin final compound C22 U2OS 24 224 Prometaphase +0.20825279020219264 1.2083281734368587e-07 BR00117026 PP-121 final compound B16 U2OS 24 374 Prometaphase +0.16643916643916645 1.23600907075559e-07 BR00117026 AZ191 final compound I18 U2OS 24 592 Prometaphase +0.13235390784197726 1.5387715778158497e-07 BR00117024 SB-203580 final compound L08 U2OS 24 924 Prometaphase +0.16105602438187802 1.7740295249201322e-07 BR00116995 WH-4-023 final compound A18 U2OS 24 617 Prometaphase +0.16638078902229847 1.8423399599357056e-07 BR00117024 PP-1 final compound A22 U2OS 24 583 Prometaphase +0.21399991646827882 1.904544240355378e-07 BR00117025 7-hydroxystaurosporine final compound L04 U2OS 24 345 Prometaphase +0.24234018586313713 2.1972564968438257e-07 BR00117026 oxibendazole final compound M19 U2OS 24 268 Prometaphase +0.19808668488871534 3.20392167224478e-07 BR00117025 epothilone-b final compound F07 U2OS 24 390 Prometaphase +0.24603174603174602 4.181665434977189e-07 BR00116995 colchicine final compound K17 U2OS 24 252 Prometaphase +0.23029281388524692 4.341552907420299e-07 BR00117024 buparlisib final compound L12 U2OS 24 285 Prometaphase +0.15092426541591944 4.791679105040559e-07 BR00116995 PP-2 final compound J10 U2OS 24 660 Prometaphase +0.16703830760434535 5.97951022905644e-07 BR00117025 AMG900 final compound N09 U2OS 24 528 Prometaphase +0.26458622283865 6.451074520026655e-07 BR00117026 colchicine final compound K17 U2OS 24 210 Prometaphase +0.1495504467347495 7.096278030275436e-07 BR00117024 AZ191 final compound I18 U2OS 24 653 Prometaphase +0.14705882352941177 7.868105467499918e-07 BR00117024 acetylcysteine final compound C24 U2OS 24 680 Prometaphase +0.18043998161147526 9.092160338719696e-07 BR00116995 danusertib final compound N18 U2OS 24 439 Prometaphase +0.14673204094573783 1.021164715639322e-06 BR00116995 PP-1 final compound A22 U2OS 24 664 Prometaphase +0.22708243881494203 1.1384041291638984e-06 BR00116995 puromycin final compound C22 U2OS 24 272 Prometaphase +0.2420324496595683 1.6010323656869098e-06 BR00117024 colchicine final compound K17 U2OS 24 234 Prometaphase +0.16600790513833993 1.670613915054847e-06 BR00117026 danusertib final compound N18 U2OS 24 506 Prometaphase +0.2138157894736842 1.6923548634923004e-06 BR00117026 NSC-663284 final compound G06 U2OS 24 304 Prometaphase +0.1479623742769295 1.952451774772642e-06 BR00117026 NVP-ADW742 final compound D16 U2OS 24 620 Prometaphase 0.5993067467124071 4.877207977966386e-89 BR00117025 AMG900 final compound N09 U2OS 24 528 SmallIrregular 0.5624505928853755 1.055036857617535e-80 BR00117025 PF-431396 final compound L20 U2OS 24 550 SmallIrregular 0.5863453815261044 1.1241180076464598e-79 BR00117025 danusertib final compound E05 U2OS 24 498 SmallIrregular @@ -449,6 +4409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.565992825773576 1.3234966336548492e-72 BR00117026 danusertib final compound E05 U2OS 24 488 SmallIrregular 0.553684868832494 6.228005657381019e-70 BR00117026 AMG900 final compound N09 U2OS 24 492 SmallIrregular 0.553014553014553 5.7416177813040685e-68 BR00117024 danusertib final compound E05 U2OS 24 481 SmallIrregular +0.5335968379446641 2.7172609814077243e-66 BR00117026 danusertib final compound N18 U2OS 24 506 SmallIrregular +0.5348751973144411 5.758308275045508e-65 BR00116995 AMG900 final compound N09 U2OS 24 491 SmallIrregular +0.5378985077704183 9.784338191094554e-65 BR00117024 danusertib final compound N18 U2OS 24 482 SmallIrregular +0.5520211815813255 1.2119143573029057e-61 BR00117024 AMG900 final compound N09 U2OS 24 433 SmallIrregular +0.5531444285031085 2.7537208784172713e-58 BR00117026 epothilone-b final compound F07 U2OS 24 410 SmallIrregular +0.5189309576837416 1.5971963917564521e-55 BR00117026 GSK1070916 final compound C04 U2OS 24 449 SmallIrregular +0.5624663091894345 3.0250877251202685e-55 BR00117024 epothilone-b final compound F07 U2OS 24 372 SmallIrregular +0.515808449423809 7.988436321784109e-54 BR00116995 danusertib final compound N18 U2OS 24 439 SmallIrregular +0.5397631133671743 6.628334657049997e-53 BR00117025 epothilone-b final compound F07 U2OS 24 390 SmallIrregular +0.5731275014293882 5.553866824022641e-41 BR00117024 SU3327 final compound I20 U2OS 24 265 SmallIrregular +0.46814837905236906 3.703985282992419e-40 BR00117024 GSK1070916 final compound C04 U2OS 24 401 SmallIrregular +0.481485598009627 2.0105843093244808e-36 BR00116995 epothilone-b final compound F07 U2OS 24 341 SmallIrregular +0.41504329004329005 2.0899545725868988e-36 BR00117026 UNC2025 final compound N06 U2OS 24 464 SmallIrregular +0.5687483093094253 2.117289832757456e-34 BR00117025 SU3327 final compound I20 U2OS 24 226 SmallIrregular +0.4195567025613502 9.750449351027106e-34 BR00117025 GSK1070916 final compound C04 U2OS 24 419 SmallIrregular +0.4181210055878742 2.050018030466884e-33 BR00117025 UNC2025 final compound N06 U2OS 24 418 SmallIrregular +0.5011480177560079 1.2195530823528439e-32 BR00117024 delanzomib final compound L11 U2OS 24 282 SmallIrregular +0.4866084340834153 3.2272983227950434e-32 BR00117025 delanzomib final compound L11 U2OS 24 295 SmallIrregular +0.30551816958277256 5.198128753288757e-31 BR00117024 RKI-1447 final compound J04 U2OS 24 743 SmallIrregular +0.575 6.7854964852395645e-31 BR00117024 AZD7762 final compound I05 U2OS 24 200 SmallIrregular +0.3062068965517241 2.0911328251514013e-30 BR00116995 RKI-1447 final compound J04 U2OS 24 725 SmallIrregular +0.4758734167527647 2.1589180061381736e-29 BR00116995 SU3327 final compound I20 U2OS 24 281 SmallIrregular +0.35012746787954285 3.896686124965439e-29 BR00117026 fludarabine-phosphate final compound N12 U2OS 24 527 SmallIrregular +0.2815478090925802 4.5307728291429325e-28 BR00117026 RKI-1447 final compound J04 U2OS 24 786 SmallIrregular +0.4635093369347843 1.1549793501883176e-27 BR00117026 SU3327 final compound I20 U2OS 24 278 SmallIrregular +0.5018871955561885 1.3123045857548901e-27 BR00117025 AZD7762 final compound I05 U2OS 24 236 SmallIrregular +0.2680047225501771 3.717579240571948e-27 BR00117025 RKI-1447 final compound J04 U2OS 24 847 SmallIrregular +0.450876983653502 3.8501201032275896e-27 BR00116995 NSC-632839 final compound M16 U2OS 24 289 SmallIrregular +0.25299698488296996 1.1922136801778162e-26 BR00117024 AC-710 final compound I03 U2OS 24 931 SmallIrregular +0.4430524220305242 5.636367330665397e-25 BR00117026 AZD7762 final compound K11 U2OS 24 275 SmallIrregular +0.44433303922355016 6.591639127748599e-25 BR00117025 puromycin final compound C22 U2OS 24 274 SmallIrregular +0.43915637772176414 1.3680096362206563e-23 BR00117026 delanzomib final compound L11 U2OS 24 267 SmallIrregular +0.4576530612244898 1.750014594032526e-23 BR00117024 NSC-632839 final compound M16 U2OS 24 240 SmallIrregular +0.4634217007098363 3.1244605891202533e-23 BR00117024 AZD7762 final compound K11 U2OS 24 234 SmallIrregular +0.2902684563758389 1.5643813548343147e-22 BR00117024 azeliragon final compound C08 U2OS 24 596 SmallIrregular +0.2906083310208738 1.036654105007623e-21 BR00116995 UNC1999 final compound H19 U2OS 24 569 SmallIrregular +0.24817388641280266 1.2663073169751108e-21 BR00116995 NVS-PAK1-1 final compound N14 U2OS 24 784 SmallIrregular +0.39600525024253835 2.1723066627144428e-21 BR00117025 thiostrepton final compound B02 U2OS 24 297 SmallIrregular +0.38587229763700354 4.4508005691567006e-21 BR00117024 ixabepilone final compound J21 U2OS 24 306 SmallIrregular +0.2809110130538702 5.5136136722236745e-21 BR00117025 azeliragon final compound C08 U2OS 24 588 SmallIrregular +0.3745878383559543 1.0748008318955018e-20 BR00117024 UNC2025 final compound N06 U2OS 24 322 SmallIrregular +0.40620974667239157 1.3353182816420023e-20 BR00116995 puromycin final compound C22 U2OS 24 272 SmallIrregular +0.3848684210526316 1.8441506351493914e-20 BR00117026 NSC-663284 final compound G06 U2OS 24 304 SmallIrregular +0.4457013574660634 2.112503091183214e-20 BR00117024 puromycin final compound C22 U2OS 24 224 SmallIrregular +0.31560437345694564 2.960909690848949e-20 BR00116995 fludarabine-phosphate final compound N12 U2OS 24 445 SmallIrregular +0.38251536128179203 4.9181086528546875e-20 BR00117026 puromycin final compound C22 U2OS 24 299 SmallIrregular +0.40550383870168843 6.32454901925731e-20 BR00117026 NSC-632839 final compound M16 U2OS 24 263 SmallIrregular +0.37285087719298243 3.284719653489562e-19 BR00117025 NSC-663284 final compound G06 U2OS 24 304 SmallIrregular +0.42517539931333037 3.40917134800662e-19 BR00117024 ryuvidine final compound A14 U2OS 24 231 SmallIrregular +0.3665413926297108 6.246415605606811e-19 BR00116995 UNC2025 final compound N06 U2OS 24 310 SmallIrregular +0.3856291310165849 1.7062518735837032e-18 BR00116995 delanzomib final compound L11 U2OS 24 271 SmallIrregular +0.2946236559139785 3.37497607022687e-18 BR00117024 UNC1999 final compound H19 U2OS 24 465 SmallIrregular +0.36918274333520634 1.0259662397262449e-17 BR00117024 NSC-663284 final compound G06 U2OS 24 285 SmallIrregular +0.27567629791642684 1.1483787815968083e-17 BR00117025 fludarabine-phosphate final compound N12 U2OS 24 510 SmallIrregular +0.28 1.1605588232289023e-17 BR00117024 fludarabine-phosphate final compound N12 U2OS 24 500 SmallIrregular +0.2681573544914831 1.7193179091480198e-17 BR00116995 BAX-channel-blocker final compound I19 U2OS 24 538 SmallIrregular +0.21297124287069652 1.9298041383086152e-17 BR00117025 AC-710 final compound I03 U2OS 24 856 SmallIrregular +0.3385093167701863 9.595127257452515e-17 BR00117026 thiostrepton final compound B02 U2OS 24 322 SmallIrregular +0.1968130472258767 2.3456099979239905e-16 BR00117025 NVS-PAK1-1 final compound N14 U2OS 24 940 SmallIrregular +0.3550686447600727 5.084033271534229e-16 BR00117024 thiostrepton final compound B02 U2OS 24 277 SmallIrregular +0.18670576735092864 5.372611867893156e-16 BR00117025 polydatin final compound K08 U2OS 24 1023 SmallIrregular +0.41529984950131366 5.847892636964141e-16 BR00117026 ponatinib final compound C20 U2OS 24 199 SmallIrregular +0.2651402024224324 9.314664726180796e-16 BR00117024 BAX-channel-blocker final compound I19 U2OS 24 492 SmallIrregular +0.41089108910891087 1.2083490848128877e-15 BR00117026 AZD7762 final compound I05 U2OS 24 202 SmallIrregular +0.3776327552297515 1.6643820385343373e-15 BR00117025 ponatinib final compound C20 U2OS 24 235 SmallIrregular +0.2298383956386293 2.1812787610099976e-15 BR00117025 KU-60019 final compound I07 U2OS 24 642 SmallIrregular +0.1988466555487674 3.002860137776838e-15 BR00117026 AC-710 final compound I03 U2OS 24 853 SmallIrregular +0.38332137447181697 3.5218133900637653e-15 BR00117025 NSC-632839 final compound M16 U2OS 24 222 SmallIrregular +0.20868694522623946 1.2576092451696417e-14 BR00117024 NVS-PAK1-1 final compound N14 U2OS 24 745 SmallIrregular +0.43902439024390244 1.3819358821254245e-14 BR00117024 ponatinib final compound C20 U2OS 24 164 SmallIrregular +0.3548764030150423 2.866892123945473e-14 BR00117025 AZD7762 final compound K11 U2OS 24 247 SmallIrregular +0.3216392109009559 3.0372585643047934e-14 BR00117025 ixabepilone final compound J21 U2OS 24 298 SmallIrregular +0.2160338785046729 1.3094816496671727e-13 BR00117026 KU-60019 final compound I07 U2OS 24 642 SmallIrregular +0.2855026389703386 1.9966236696938368e-13 BR00117025 UNC1999 final compound H19 U2OS 24 362 SmallIrregular +0.38707890070921985 3.0712023125504077e-13 BR00117025 ryuvidine final compound A14 U2OS 24 192 SmallIrregular +0.20253164556962025 3.59807662541858e-13 BR00116995 simvastatin final compound N24 U2OS 24 711 SmallIrregular +0.3288387857353375 4.111712077106782e-13 BR00116995 ixabepilone final compound J21 U2OS 24 261 SmallIrregular +0.20501835985312117 4.2044721250727736e-13 BR00117024 KU-60019 final compound I07 U2OS 24 688 SmallIrregular +0.20355541653633616 4.720163074957521e-13 BR00117026 JTE-607 final compound C14 U2OS 24 695 SmallIrregular +0.3783029065577708 3.542977603875562e-12 BR00116995 ponatinib final compound C20 U2OS 24 181 SmallIrregular +0.16614745586708204 5.1084172140256985e-12 BR00117026 polydatin final compound K08 U2OS 24 963 SmallIrregular +0.4358974358974359 7.06720586829997e-12 BR00117026 LDN-212854 final compound K01 U2OS 24 135 SmallIrregular +0.23223352498894295 1.085641096755747e-11 BR00117025 BAX-channel-blocker final compound I19 U2OS 24 475 SmallIrregular +0.24731587625118465 4.8426329292097793e-11 BR00117025 PP-121 final compound B16 U2OS 24 391 SmallIrregular +0.24296491361982545 1.0242823178135677e-10 BR00117025 TG-02 final compound L21 U2OS 24 396 SmallIrregular +0.2422279792746114 1.9681997426439068e-10 BR00117026 PHA-793887 final compound I06 U2OS 24 388 SmallIrregular +0.26306280875088217 2.1865548040213745e-10 BR00117026 PHA-793887 final compound E13 U2OS 24 327 SmallIrregular +0.25501432664756446 2.233749209913149e-10 BR00117026 UNC1999 final compound H19 U2OS 24 349 SmallIrregular +0.2753812913065582 7.891403325169545e-10 BR00117026 ixabepilone final compound J21 U2OS 24 280 SmallIrregular +0.42272727272727273 9.832381737659262e-10 BR00117025 LDN-212854 final compound K01 U2OS 24 110 SmallIrregular 0.6723076923076923 3.684627809820627e-43 BR00117013 thiostrepton final compound B02 U2OS 48 200 ADCCM 0.6214285714285714 3.828764249337873e-41 BR00117010 delanzomib final compound L11 U2OS 48 224 ADCCM 0.40900735294117646 8.917603167290163e-39 BR00117013 fludarabine-phosphate final compound N12 U2OS 48 510 ADCCM @@ -459,6 +4509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.6240082280340876 1.6122454226550327e-30 BR00117013 puromycin final compound C22 U2OS 48 164 ADCCM 0.5199276647046309 8.028441439690679e-30 BR00117013 BVT-948 final compound B12 U2OS 48 236 ADCCM 0.4747300806341397 5.529185210043402e-28 BR00117013 delanzomib final compound L11 U2OS 48 270 ADCCM +0.537242308090749 8.971892610874177e-27 BR00117012 delanzomib final compound L11 U2OS 48 196 ADCCM +0.47560975609756095 1.5294176537193298e-25 BR00117010 AZD7762 final compound K11 U2OS 48 246 ADCCM +0.1995912388270484 1.807379311714494e-25 BR00117012 RKI-1447 final compound J04 U2OS 48 1434 ADCCM +0.3146853146853147 1.9987694574864865e-25 BR00117011 fludarabine-phosphate final compound N12 U2OS 48 572 ADCCM +0.5918367346938775 4.992727513903755e-25 BR00117010 NSC-663284 final compound G06 U2OS 48 154 ADCCM +0.6078431372549019 1.1608612751444737e-24 BR00117010 thiostrepton final compound B02 U2OS 48 144 ADCCM +0.5243079386867994 4.2311640323214906e-24 BR00117011 delanzomib final compound L11 U2OS 48 186 ADCCM +0.6385084745762711 7.741459545538443e-24 BR00117011 NSC-663284 final compound G06 U2OS 48 118 ADCCM +0.5244273024777933 8.249556736348434e-24 BR00117013 NSC-632839 final compound M16 U2OS 48 184 ADCCM +0.6026233738307709 1.257707675295522e-23 BR00117013 ryuvidine final compound A14 U2OS 48 142 ADCCM +0.4163272861902999 2.010523454168466e-23 BR00117013 colchicine final compound K17 U2OS 48 296 ADCCM +0.4314538419016031 4.264216941006437e-23 BR00117013 AZD7762 final compound K11 U2OS 48 268 ADCCM +0.23793859649122806 4.713746092126655e-23 BR00117012 deferasirox final compound L14 U2OS 48 912 ADCCM +0.6246031746031746 5.696675515081185e-23 BR00117013 ponatinib final compound C20 U2OS 48 120 ADCCM +0.17886003762851152 5.832874527130847e-23 BR00117010 RKI-1447 final compound J04 U2OS 48 1612 ADCCM +0.4075142613599108 6.174574744864929e-23 BR00117010 briciclib final compound H01 U2OS 48 302 ADCCM +0.3183673469387755 2.370564684052484e-22 BR00117012 AMG900 final compound N09 U2OS 48 490 ADCCM +0.5228571428571429 5.519271458765324e-22 BR00117013 AZD7762 final compound I05 U2OS 48 168 ADCCM +0.4787890382132096 7.54206554603289e-22 BR00117012 AZD7762 final compound K11 U2OS 48 206 ADCCM +0.20325829215280658 2.093098888491959e-21 BR00117011 AZ191 final compound I18 U2OS 48 1154 ADCCM +0.3786047890874045 2.0948892735763594e-21 BR00117011 briciclib final compound H01 U2OS 48 328 ADCCM +0.519403194172037 2.4750821478005767e-21 BR00117013 NSC-663284 final compound G06 U2OS 48 166 ADCCM +0.3031496062992126 5.300740906752459e-21 BR00117010 AMG900 final compound N09 U2OS 48 508 ADCCM +0.37205489545915077 5.570505836613621e-21 BR00117012 briciclib final compound H01 U2OS 48 330 ADCCM +0.5085714285714286 6.2105517332938736e-21 BR00117011 thiostrepton final compound B02 U2OS 48 170 ADCCM +0.5371304974765682 3.0167307811396633e-20 BR00117012 NSC-632839 final compound M16 U2OS 48 152 ADCCM +0.3815789473684211 4.129720305307946e-20 BR00117010 colchicine final compound K17 U2OS 48 304 ADCCM +0.39705882352941174 1.554394932127786e-19 BR00117010 oxibendazole final compound M19 U2OS 48 272 ADCCM +0.5900826446280992 3.5843724987785966e-19 BR00117012 AZD7762 final compound I05 U2OS 48 110 ADCCM +0.5560804263565892 1.0658765130476858e-18 BR00117010 AZD7762 final compound I05 U2OS 48 128 ADCCM +0.2618028569864813 1.1356140337281804e-18 BR00117013 AMG900 final compound N09 U2OS 48 604 ADCCM +0.5777471686562595 3.336215313856056e-18 BR00117012 ponatinib final compound C20 U2OS 48 108 ADCCM +0.42990654205607476 3.942444634830502e-18 BR00117013 buparlisib final compound L12 U2OS 48 214 ADCCM +0.4112509534706331 5.291457530569507e-18 BR00117011 colchicine final compound K17 U2OS 48 230 ADCCM +0.5312217194570136 1.022376209471307e-17 BR00117011 NSC-632839 final compound M16 U2OS 48 136 ADCCM +0.41517857142857145 1.134571302275678e-17 BR00117013 CYT-997 final compound E06 U2OS 48 224 ADCCM +0.6566666666666666 4.178479087772911e-17 BR00117010 puromycin final compound C22 U2OS 48 88 ADCCM +0.22697420477923722 1.3840969680980338e-16 BR00117012 JTE-607 final compound C14 U2OS 48 710 ADCCM +0.16007649043433425 1.5156586709693043e-16 BR00117013 lonafarnib final compound J06 U2OS 48 1434 ADCCM +0.48496383707651314 4.953217314687001e-16 BR00117011 BVT-948 final compound B12 U2OS 48 148 ADCCM +0.23123123123123124 5.093900522224248e-16 BR00117013 JTE-607 final compound C14 U2OS 48 666 ADCCM +0.44094591063496213 7.253375223953956e-16 BR00117012 buparlisib final compound L12 U2OS 48 172 ADCCM +0.16191024013831545 7.294003550334802e-16 BR00117012 PP-2 final compound J10 U2OS 48 1348 ADCCM +0.19710378117457764 7.960158659438638e-16 BR00117010 deferasirox final compound L14 U2OS 48 904 ADCCM +0.5192846656879755 1.220463221066243e-15 BR00117010 BVT-948 final compound B12 U2OS 48 118 ADCCM +0.18679944607363963 1.2220040989982859e-15 BR00117012 AZ191 final compound I18 U2OS 48 990 ADCCM +0.18932357632048036 1.3099123961815099e-15 BR00117013 AZ191 final compound I18 U2OS 48 968 ADCCM +0.33950388744909293 1.6123902813112853e-15 BR00117013 oxibendazole final compound M19 U2OS 48 296 ADCCM +0.1348373557187828 1.6195024189368255e-15 BR00117011 SB-203580 final compound L08 U2OS 48 1906 ADCCM +0.349910430202401 1.6597258379279129e-15 BR00117011 CYT-997 final compound C09 U2OS 48 274 ADCCM +0.371831955922865 2.393359136663054e-15 BR00117013 CYT-997 final compound C09 U2OS 48 240 ADCCM +0.5128135593220339 4.202092573087627e-15 BR00117011 ryuvidine final compound A14 U2OS 48 118 ADCCM +0.24754507213580423 4.7954946235219706e-15 BR00117011 AMG900 final compound N09 U2OS 48 542 ADCCM +0.3489005532699674 5.2821181623021685e-15 BR00117012 colchicine final compound K17 U2OS 48 266 ADCCM +0.4027585499666718 6.070371193165833e-15 BR00117011 AZD7762 final compound K11 U2OS 48 198 ADCCM +0.41397849462365593 1.1823238551398601e-14 BR00117013 buparlisib final compound D11 U2OS 48 186 ADCCM +0.6791666666666667 3.43963480596184e-14 BR00117011 SU3327 final compound I20 U2OS 48 60 ADCCM +0.32031007751937984 4.2183440920177717e-14 BR00117010 GK921 final compound H24 U2OS 48 300 ADCCM +0.4281516309138995 4.328896928452762e-14 BR00117013 romidepsin final compound N19 U2OS 48 164 ADCCM +0.13407505374109976 4.561994030139446e-14 BR00117011 PP-2 final compound J10 U2OS 48 1734 ADCCM +0.32816901408450705 5.344639481640205e-14 BR00117013 briciclib final compound H01 U2OS 48 284 ADCCM +0.6971153846153846 6.770170285478615e-14 BR00117010 SU3327 final compound I20 U2OS 48 52 ADCCM +0.37627948375611925 7.064919880123342e-14 BR00117010 buparlisib final compound D11 U2OS 48 214 ADCCM +0.6274038461538461 1.5609037732985568e-13 BR00117011 puromycin final compound C22 U2OS 48 78 ADCCM +0.32643557880967955 1.5862043105535394e-13 BR00117012 oxibendazole final compound M19 U2OS 48 278 ADCCM +0.15188850834929665 1.9788868059001493e-13 BR00117013 RKI-1447 final compound J04 U2OS 48 1288 ADCCM +0.19633507853403143 2.729049384023692e-13 BR00117010 BMS-536924 final compound B15 U2OS 48 764 ADCCM +0.6043758967001435 3.0004143835574603e-13 BR00117010 ryuvidine final compound A14 U2OS 48 82 ADCCM +0.15057349711217766 3.0543731933463527e-13 BR00117013 PP-2 final compound J10 U2OS 48 1292 ADCCM +0.1834014673633484 3.506551278922316e-13 BR00117010 AZ191 final compound I18 U2OS 48 860 ADCCM +0.13691011897459038 3.6376730470010853e-13 BR00117011 RKI-1447 final compound J04 U2OS 48 1558 ADCCM +0.2038113641285336 3.891632138452862e-13 BR00117013 BMS-536924 final compound B15 U2OS 48 694 ADCCM +0.17583821304413105 4.1428291740137945e-13 BR00117011 deferasirox final compound L14 U2OS 48 930 ADCCM +0.27715629423314003 9.886269236595696e-13 BR00117012 GK921 final compound H24 U2OS 48 362 ADCCM +0.37223639455782315 1.5603313317729797e-12 BR00117011 AZD7762 final compound I05 U2OS 48 196 ADCCM +0.3088489587249079 2.27679948335328e-12 BR00117010 CYT-997 final compound C09 U2OS 48 282 ADCCM +0.5345849802371542 2.346247383306814e-12 BR00117013 LDN-212854 final compound K01 U2OS 48 92 ADCCM +0.12023305084745763 2.6442946555593614e-12 BR00117013 SB-203580 final compound L08 U2OS 48 1888 ADCCM +0.34487297617480583 6.425027674974254e-12 BR00117011 CYT-997 final compound E06 U2OS 48 214 ADCCM +0.10993706923444693 1.1677732734058504e-11 BR00117012 L-Cystine final compound O08 U2OS 48 2124 ADCCM +0.17245138052544717 1.6776740461729647e-11 BR00117013 deferasirox final compound L14 U2OS 48 846 ADCCM +0.4312328082020505 4.148318990706926e-11 BR00117010 ponatinib final compound C20 U2OS 48 124 ADCCM +0.11458449577800096 4.55852211819735e-11 BR00117010 SB-203580 final compound L08 U2OS 48 1854 ADCCM +0.1412792337397492 4.730428908563055e-11 BR00117010 ZK-93423 final compound K20 U2OS 48 1216 ADCCM +0.12002325647352449 4.898799895395238e-11 BR00117013 AC-710 final compound I03 U2OS 48 1680 ADCCM +0.3796747967479675 4.957263860073485e-11 BR00117011 buparlisib final compound L12 U2OS 48 164 ADCCM +0.3671760797342193 5.373950182753449e-11 BR00117010 buparlisib final compound L12 U2OS 48 172 ADCCM +0.4778743180440493 7.586993094050941e-11 BR00117010 NSC-632839 final compound M16 U2OS 48 98 ADCCM +0.26127017178552836 8.877313354777623e-11 BR00117013 GK921 final compound H24 U2OS 48 340 ADCCM +0.11621124076910526 9.35279631311438e-11 BR00117010 ingenol-mebutate final compound M11 U2OS 48 1744 ADCCM 0.4410191285022621 2.0488670127037857e-128 BR00117012 AC-710 final compound I03 U2OS 48 1462 Anaphase 0.6901252437938744 8.332002845009347e-124 BR00117011 AMG900 final compound N09 U2OS 48 542 Anaphase 0.6803063043066699 5.860404120520892e-123 BR00117012 fludarabine-phosphate final compound N12 U2OS 48 554 Anaphase @@ -469,6 +4609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.6909448818897638 3.491207463425055e-116 BR00117010 AMG900 final compound N09 U2OS 48 508 Anaphase 0.6376279349789283 7.696085600606625e-116 BR00117013 AMG900 final compound N09 U2OS 48 604 Anaphase 0.3579555695554056 3.644330046228315e-107 BR00117012 PETCM final compound I04 U2OS 48 1874 Anaphase +0.6612660843430074 4.498720924223909e-105 BR00117013 danusertib final compound E05 U2OS 48 504 Anaphase +0.5620026159446554 4.749677777346545e-104 BR00117012 PF-431396 final compound L20 U2OS 48 712 Anaphase +0.651593137254902 9.179833118394002e-103 BR00117013 fludarabine-phosphate final compound N12 U2OS 48 510 Anaphase +0.6188811188811189 1.0036479340297938e-102 BR00117011 fludarabine-phosphate final compound N12 U2OS 48 572 Anaphase +0.5416823258820522 1.1321464310930638e-98 BR00117013 PF-431396 final compound L20 U2OS 48 728 Anaphase +0.5472504754816836 1.914068912255885e-96 BR00117011 PF-431396 final compound L20 U2OS 48 696 Anaphase +0.6051659566800942 1.7511371176079514e-95 BR00117010 danusertib final compound N18 U2OS 48 556 Anaphase +0.622731549939508 2.266952966082278e-94 BR00117011 danusertib final compound E05 U2OS 48 516 Anaphase +0.6209663405235919 3.3351828656324647e-93 BR00117010 fludarabine-phosphate final compound N12 U2OS 48 514 Anaphase +0.634818254787295 5.725642993710116e-87 BR00117013 danusertib final compound N18 U2OS 48 456 Anaphase +0.5847250735171725 1.4364990133811669e-85 BR00117011 danusertib final compound N18 U2OS 48 536 Anaphase +0.5317460317460317 7.514339427208726e-82 BR00117012 KU-60019 final compound I07 U2OS 48 630 Anaphase +0.5329808148600095 3.7713723092702437e-78 BR00117010 PF-431396 final compound L20 U2OS 48 596 Anaphase +0.4342105263157895 1.3390216701921937e-77 BR00117012 deferasirox final compound L14 U2OS 48 912 Anaphase +0.5743870967741935 1.5520094494377278e-76 BR00117011 GSK1070916 final compound C04 U2OS 48 500 Anaphase +0.41439868139630714 4.145258645412227e-70 BR00117010 deferasirox final compound L14 U2OS 48 904 Anaphase +0.5317755511022044 1.9848274347733124e-65 BR00117012 danusertib final compound E05 U2OS 48 500 Anaphase +0.5610328638497653 4.2582760183557215e-62 BR00117010 GSK1070916 final compound C04 U2OS 48 426 Anaphase +0.5541015899817082 9.822300415629161e-59 BR00117013 GSK1070916 final compound C04 U2OS 48 414 Anaphase +0.2563710499490316 4.8005462786182806e-57 BR00117011 AC-710 final compound I03 U2OS 48 1962 Anaphase +0.29928661359597747 1.3327431581105546e-56 BR00117012 quinine final compound A05 U2OS 48 1418 Anaphase +0.3790033007716669 9.571832511526878e-55 BR00117013 deferasirox final compound L14 U2OS 48 846 Anaphase +0.4900702439835405 7.399109866361025e-54 BR00117010 KG-5 final compound C13 U2OS 48 490 Anaphase +0.35525680560849127 7.9978405246130835e-53 BR00117011 deferasirox final compound L14 U2OS 48 930 Anaphase +0.5413946910356832 2.3946888902489565e-52 BR00117012 KG-5 final compound C13 U2OS 48 384 Anaphase +0.5161883249180619 2.6592156150615747e-52 BR00117011 epothilone-b final compound F07 U2OS 48 426 Anaphase +0.463254127158022 2.8298735133059903e-50 BR00117012 epothilone-b final compound F07 U2OS 48 514 Anaphase +0.4625726858400126 3.803663055929429e-49 BR00117010 epothilone-b final compound F07 U2OS 48 504 Anaphase +0.36417231624640295 2.895427966022435e-48 BR00117011 JTE-607 final compound C14 U2OS 48 812 Anaphase +0.3668255382906447 1.4029207099595239e-47 BR00117010 KU-60019 final compound I07 U2OS 48 786 Anaphase +0.3299089495891628 2.4237021235834655e-46 BR00117012 amlodipine final compound A03 U2OS 48 950 Anaphase +0.24795725913951047 9.500625378622665e-46 BR00117013 AC-710 final compound I03 U2OS 48 1680 Anaphase +0.27628024107284754 1.1201692065594609e-45 BR00117012 fludarabine final compound B06 U2OS 48 1342 Anaphase +0.3769544231682228 1.5484439401668638e-45 BR00117012 JTE-607 final compound C14 U2OS 48 710 Anaphase +0.38288288288288286 6.776413228212275e-44 BR00117013 JTE-607 final compound C14 U2OS 48 666 Anaphase +0.32752262010342004 8.970963023878314e-44 BR00117010 JTE-607 final compound C14 U2OS 48 908 Anaphase +0.4699788397108094 3.3183576531657185e-43 BR00117012 GSK1070916 final compound C04 U2OS 48 424 Anaphase +0.24535315985130113 4.837628409009752e-43 BR00117010 AC-710 final compound I03 U2OS 48 1614 Anaphase +0.31655118809682437 1.3729467172736916e-42 BR00117012 polydatin final compound K08 U2OS 48 950 Anaphase +0.4869791666666667 1.1941734381915576e-41 BR00117011 KG-5 final compound C13 U2OS 48 384 Anaphase +0.4445986164736165 2.5466550391283813e-40 BR00117013 epothilone-b final compound F07 U2OS 48 444 Anaphase +0.3346126303909501 4.160087047917813e-39 BR00117013 KU-60019 final compound I07 U2OS 48 778 Anaphase +0.3523439780743607 5.674428494080752e-38 BR00117012 SKLB1002 final compound P17 U2OS 48 678 Anaphase +0.2619387429058321 4.99870760644876e-35 BR00117011 fludarabine final compound B06 U2OS 48 1148 Anaphase +0.3567002569803367 7.892937428346327e-34 BR00117010 SKLB1002 final compound P17 U2OS 48 590 Anaphase +0.22155987888250672 2.5337863242925e-33 BR00117013 fludarabine final compound B06 U2OS 48 1524 Anaphase +0.3022850314588109 3.907066711693379e-33 BR00117011 KU-60019 final compound I07 U2OS 48 812 Anaphase +0.5115757824244909 1.1460067066135029e-32 BR00117013 delanzomib final compound L11 U2OS 48 270 Anaphase +0.39470198675496687 6.882017119213507e-32 BR00117013 SKLB1002 final compound P17 U2OS 48 450 Anaphase +0.27757546573569686 9.968221131607213e-31 BR00117010 FK-866 final compound L09 U2OS 48 892 Anaphase +0.4109246791500105 4.2075265387323976e-30 BR00117013 KG-5 final compound C13 U2OS 48 388 Anaphase +0.3128952611972624 4.9209017939427376e-30 BR00117011 SKLB1002 final compound P17 U2OS 48 680 Anaphase +0.4179835205147017 6.756422529306923e-30 BR00117010 BAX-channel-blocker final compound I19 U2OS 48 376 Anaphase +0.43452380952380953 7.154126345081769e-29 BR00117012 ixabepilone final compound J21 U2OS 48 336 Anaphase +0.557028902931731 1.85822356593699e-28 BR00117012 delanzomib final compound L11 U2OS 48 196 Anaphase +0.396967899281524 4.097891412685348e-28 BR00117010 azeliragon final compound C08 U2OS 48 390 Anaphase +0.23976872478432304 6.02572272582745e-27 BR00117013 FK-866 final compound D08 U2OS 48 1046 Anaphase +0.37643855079327493 2.040603090898472e-26 BR00117011 BAX-channel-blocker final compound I19 U2OS 48 410 Anaphase +0.40154220359157483 3.523990113183466e-25 BR00117012 azeliragon final compound C08 U2OS 48 342 Anaphase +0.42713178294573645 4.950118889143795e-25 BR00117010 ixabepilone final compound J21 U2OS 48 300 Anaphase +0.5620041140170438 1.6993756017639257e-24 BR00117013 puromycin final compound C22 U2OS 48 164 Anaphase +0.4031526152376403 1.7308759097921516e-23 BR00117013 azeliragon final compound C08 U2OS 48 316 Anaphase +0.24383680320545795 5.1269803281811853e-23 BR00117011 aminopurvalanol-a final compound K03 U2OS 48 860 Anaphase +0.44667044890433305 7.164301637769502e-22 BR00117013 BVT-948 final compound B12 U2OS 48 236 Anaphase +0.4969114619080302 1.974170753933559e-21 BR00117011 delanzomib final compound L11 U2OS 48 186 Anaphase +0.38649354891393106 2.3805385501626164e-21 BR00117011 BI-2536 final compound E21 U2OS 48 312 Anaphase +0.21851210304241617 2.2463034055520487e-20 BR00117010 FK-866 final compound D08 U2OS 48 950 Anaphase +0.17516101453405528 5.690717358550954e-20 BR00117010 fludarabine final compound B06 U2OS 48 1452 Anaphase +0.3609467455621302 5.866585316383902e-20 BR00117013 ixabepilone final compound J21 U2OS 48 338 Anaphase +0.22544935190924034 1.1776641672832105e-19 BR00117013 FK-866 final compound L09 U2OS 48 860 Anaphase +0.23091120081972272 2.8621889894380953e-19 BR00117012 FK-866 final compound D08 U2OS 48 804 Anaphase +0.43372434017595307 4.135121183569226e-19 BR00117012 BVT-948 final compound B12 U2OS 48 220 Anaphase +0.42936507936507934 5.345335976574011e-19 BR00117010 delanzomib final compound L11 U2OS 48 224 Anaphase +0.31288934701743376 9.241802191420161e-19 BR00117011 ixabepilone final compound J21 U2OS 48 424 Anaphase +0.4065040650406504 1.460218839646217e-18 BR00117010 AZD7762 final compound K11 U2OS 48 246 Anaphase +0.6482213438735178 1.5818951650497586e-18 BR00117013 LDN-212854 final compound K01 U2OS 48 92 Anaphase +0.38662244333886125 1.8449750132908388e-18 BR00117013 AZD7762 final compound K11 U2OS 48 268 Anaphase +0.4369410301783921 5.010613063040203e-18 BR00117012 AZD7762 final compound K11 U2OS 48 206 Anaphase +0.3696478959636854 5.932750842236151e-18 BR00117011 BI-2536 final compound I14 U2OS 48 286 Anaphase +0.44300876788186433 5.978394866970498e-18 BR00117011 AZD7762 final compound K11 U2OS 48 198 Anaphase +0.3849970640046976 8.175479748613561e-18 BR00117012 UNC2025 final compound N06 U2OS 48 262 Anaphase +0.5685644322007959 1.3247655033447167e-17 BR00117012 ponatinib final compound C20 U2OS 48 108 Anaphase +0.375 2.0374315631447512e-17 BR00117010 oxibendazole final compound M19 U2OS 48 272 Anaphase +0.2713840213840214 2.854211091808463e-17 BR00117011 menadione final compound M12 U2OS 48 518 Anaphase +0.1979381443298969 4.957047083735647e-17 BR00117010 NNC-55-0396 final compound A16 U2OS 48 970 Anaphase +0.5286321580395099 8.98275344394146e-17 BR00117010 ponatinib final compound C20 U2OS 48 124 Anaphase +0.28391588519465755 8.986002198188812e-17 BR00117012 menadione final compound M12 U2OS 48 460 Anaphase +0.5377627118644068 1.2284248230350294e-16 BR00117011 NSC-663284 final compound G06 U2OS 48 118 Anaphase +0.20250585768898755 1.3641700750869742e-16 BR00117011 FK-866 final compound D08 U2OS 48 900 Anaphase +0.3946224256292906 1.561638584227049e-16 BR00117011 oxibendazole final compound M19 U2OS 48 230 Anaphase 0.3885459997295771 7.366667971335171e-144 BR00117012 L-Cystine final compound O08 U2OS 48 2124 Apoptosis 0.6277726715686275 8.149621582589408e-95 BR00117013 fludarabine-phosphate final compound N12 U2OS 48 510 Apoptosis 0.5612575972215875 4.100405770900713e-81 BR00117012 fludarabine-phosphate final compound N12 U2OS 48 554 Apoptosis @@ -479,6 +4709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.38949216358869526 2.243041574479361e-63 BR00117011 deferasirox final compound L14 U2OS 48 930 Apoptosis 0.48776223776223776 4.558022588397614e-62 BR00117011 fludarabine-phosphate final compound N12 U2OS 48 572 Apoptosis 0.2764729856077739 6.645684701446764e-59 BR00117011 PP-2 final compound J10 U2OS 48 1734 Apoptosis +0.3154688703757758 2.72322323645901e-57 BR00117013 PP-2 final compound J10 U2OS 48 1292 Apoptosis +0.37452171183015126 4.856221823698239e-57 BR00117010 deferasirox final compound L14 U2OS 48 904 Apoptosis +0.2918336189146664 1.9461803401363644e-55 BR00117012 AC-710 final compound I03 U2OS 48 1462 Apoptosis +0.3810272536687631 2.9046715184548883e-55 BR00117013 deferasirox final compound L14 U2OS 48 846 Apoptosis +0.2912723694621986 3.263547442580709e-54 BR00117010 PP-2 final compound J10 U2OS 48 1434 Apoptosis +0.46718021970547224 2.2983776359814443e-48 BR00117012 danusertib final compound N18 U2OS 48 484 Apoptosis +0.28063319790679103 3.5522966610212856e-47 BR00117012 PP-2 final compound J10 U2OS 48 1348 Apoptosis +0.44285714285714284 1.3447118672243279e-43 BR00117012 AMG900 final compound N09 U2OS 48 490 Apoptosis +0.4272330233868695 5.567910606375743e-42 BR00117013 danusertib final compound E05 U2OS 48 504 Apoptosis +0.36115682861212217 1.1475555615936396e-41 BR00117012 JTE-607 final compound C14 U2OS 48 710 Apoptosis +0.37237237237237236 1.7562650634739896e-41 BR00117013 JTE-607 final compound C14 U2OS 48 666 Apoptosis +0.25522439498617455 5.05577209102213e-41 BR00117012 quinine final compound A05 U2OS 48 1418 Apoptosis +0.32669609325464566 9.382939210650086e-39 BR00117011 JTE-607 final compound C14 U2OS 48 812 Apoptosis +0.42151129457631004 4.564320186504149e-37 BR00117013 danusertib final compound N18 U2OS 48 456 Apoptosis +0.26763309395216334 4.915748909898364e-37 BR00117010 polydatin final compound K08 U2OS 48 1160 Apoptosis +0.32428695414000547 1.2028977092598684e-36 BR00117013 KU-60019 final compound I07 U2OS 48 778 Apoptosis +0.2986653290879749 3.469519090393719e-36 BR00117010 JTE-607 final compound C14 U2OS 48 908 Apoptosis +0.3198905981581225 4.5331002647865834e-36 BR00117010 KU-60019 final compound I07 U2OS 48 786 Apoptosis +0.23676265920320388 5.379752248925641e-36 BR00117013 PP-1 final compound A22 U2OS 48 1444 Apoptosis +0.3956692913385827 6.852430189767604e-36 BR00117010 AMG900 final compound N09 U2OS 48 508 Apoptosis +0.24418016672390092 1.0762158170701546e-35 BR00117012 fludarabine final compound B06 U2OS 48 1342 Apoptosis +0.31327122860069256 1.3577509129373356e-35 BR00117011 KU-60019 final compound I07 U2OS 48 812 Apoptosis +0.20801772960607076 1.4592088339545453e-35 BR00117010 SB-203580 final compound L08 U2OS 48 1854 Apoptosis +0.27581399178460664 1.9562048274228244e-35 BR00117013 FK-866 final compound D08 U2OS 48 1046 Apoptosis +0.3523809523809524 4.12112138568817e-35 BR00117012 KU-60019 final compound I07 U2OS 48 630 Apoptosis +0.44597310939384466 3.2062564630139346e-33 BR00117010 ganetespib final compound M10 U2OS 48 366 Apoptosis +0.44977487967706875 1.5461046961684633e-31 BR00117012 azeliragon final compound C08 U2OS 48 342 Apoptosis +0.33953259263313446 2.3710650573655964e-31 BR00117013 AMG900 final compound N09 U2OS 48 604 Apoptosis +0.3283287837427965 1.5233753697066013e-30 BR00117010 danusertib final compound E05 U2OS 48 628 Apoptosis +0.29581151832460734 7.044504929638411e-30 BR00117010 BMS-536924 final compound B15 U2OS 48 764 Apoptosis +0.34876625009344014 9.259905447411519e-30 BR00117011 AMG900 final compound N09 U2OS 48 542 Apoptosis +0.4641638981173865 1.0650904619920945e-29 BR00117011 ganetespib final compound I17 U2OS 48 300 Apoptosis +0.42362333798797885 1.1268377884123425e-29 BR00117013 ganetespib final compound M10 U2OS 48 364 Apoptosis +0.3066975159366109 9.966554225994994e-29 BR00117012 SKLB1002 final compound P17 U2OS 48 678 Apoptosis +0.18310598111227702 2.5008245177452022e-28 BR00117011 SB-203580 final compound L08 U2OS 48 1906 Apoptosis +0.18114406779661016 1.79503166335329e-27 BR00117013 SB-203580 final compound L08 U2OS 48 1888 Apoptosis +0.3294745241373985 2.1460172158387416e-27 BR00117010 danusertib final compound N18 U2OS 48 556 Apoptosis +0.4048802946593002 3.8790309728541885e-27 BR00117012 NVP-HSP990 final compound E23 U2OS 48 360 Apoptosis +0.20543175487465182 4.592895747720174e-27 BR00117010 PP-1 final compound A22 U2OS 48 1440 Apoptosis +0.3166286489764098 1.5294147093203748e-26 BR00117010 SKLB1002 final compound P17 U2OS 48 590 Apoptosis +0.2163861585418673 3.015995186660295e-26 BR00117011 polydatin final compound K08 U2OS 48 1254 Apoptosis +0.3285524052599456 3.2341104480572924e-26 BR00117011 danusertib final compound N18 U2OS 48 536 Apoptosis +0.1989247311827957 3.684764504948207e-26 BR00117012 SB-203580 final compound L08 U2OS 48 1488 Apoptosis +0.19475479222352624 8.256293798851165e-26 BR00117013 fludarabine final compound B06 U2OS 48 1524 Apoptosis +0.24994231598800173 4.514167124378795e-25 BR00117010 FK-866 final compound L09 U2OS 48 892 Apoptosis +0.3262311242550522 5.8667603601053385e-25 BR00117011 danusertib final compound E05 U2OS 48 516 Apoptosis +0.375809109485202 6.377203970639165e-25 BR00117010 azeliragon final compound C08 U2OS 48 390 Apoptosis +0.34722590139808684 9.317123253092818e-25 BR00117013 SKLB1002 final compound P17 U2OS 48 450 Apoptosis +0.27975962419416633 2.5045749063768368e-24 BR00117013 BMS-536924 final compound B15 U2OS 48 694 Apoptosis +0.3857985047590818 1.4569924361586684e-23 BR00117011 ganetespib final compound M10 U2OS 48 348 Apoptosis +0.3493386801744759 5.543279071979202e-23 BR00117013 GSK1070916 final compound C04 U2OS 48 414 Apoptosis +0.3831292047610833 1.0188501767886677e-22 BR00117011 geldanamycin final compound L01 U2OS 48 340 Apoptosis +0.37422299922299923 1.5596009417982133e-22 BR00117013 RGB-286638 final compound K21 U2OS 48 352 Apoptosis +0.3764367816091954 2.4035761838332016e-22 BR00117012 ganetespib final compound M10 U2OS 48 348 Apoptosis +0.21678102826515103 2.8220243100133385e-22 BR00117010 WH-4-023 final compound A18 U2OS 48 1054 Apoptosis +0.19895401541858754 4.161263196020548e-22 BR00117013 lonafarnib final compound F22 U2OS 48 1244 Apoptosis +0.22473279457768508 8.200802721779826e-22 BR00117013 polydatin final compound K08 U2OS 48 960 Apoptosis +0.19692058346839547 2.4628994186001783e-21 BR00117011 simvastatin final compound N24 U2OS 48 1234 Apoptosis +0.3409045226130653 4.2858335923843706e-21 BR00117010 RGB-286638 final compound K21 U2OS 48 400 Apoptosis +0.2510339123242349 5.0889180269868996e-21 BR00117011 BMS-536924 final compound B15 U2OS 48 744 Apoptosis +0.260257298795807 8.793793241039325e-21 BR00117011 SKLB1002 final compound P17 U2OS 48 680 Apoptosis +0.22013324450366423 1.3430180969223356e-20 BR00117010 FK-866 final compound D08 U2OS 48 950 Apoptosis +0.3812070282658518 1.9399256587681375e-20 BR00117010 PP-121 final compound B16 U2OS 48 308 Apoptosis +0.30057238587184143 4.084691709058458e-20 BR00117012 AVL-292 final compound A24 U2OS 48 494 Apoptosis +0.33989160829081266 9.835063085258031e-20 BR00117011 azeliragon final compound C08 U2OS 48 372 Apoptosis +0.3510748510748511 1.1794534421466077e-19 BR00117012 7-hydroxystaurosporine final compound L04 U2OS 48 352 Apoptosis +0.36673035586338665 1.3530139632652092e-19 BR00117013 azeliragon final compound C08 U2OS 48 316 Apoptosis +0.166800592484438 3.185570632154647e-19 BR00117012 simvastatin final compound N24 U2OS 48 1538 Apoptosis +0.37327633756205186 6.3347169408044e-19 BR00117011 NSC-95397 final compound D03 U2OS 48 296 Apoptosis +0.3310814654681989 8.0781571114138845e-19 BR00117012 RGB-286638 final compound K21 U2OS 48 374 Apoptosis +0.21496115427302998 8.753149057969365e-19 BR00117011 FK-866 final compound D08 U2OS 48 900 Apoptosis +0.34242308140793926 1.1429429052789964e-18 BR00117010 geldanamycin final compound L01 U2OS 48 346 Apoptosis +0.2864838709677419 1.6741857793760447e-18 BR00117011 GSK1070916 final compound C04 U2OS 48 500 Apoptosis +0.18680318543799773 2.6021002617467764e-18 BR00117010 lonafarnib final compound F22 U2OS 48 1172 Apoptosis +0.3089622641509434 2.8459386170562865e-18 BR00117010 BVT-948 final compound O16 U2OS 48 424 Apoptosis +0.3586628093860495 4.120192771695909e-18 BR00117010 ganetespib final compound I17 U2OS 48 306 Apoptosis +0.35947712418300654 5.855164460722166e-18 BR00117011 7-hydroxystaurosporine final compound L04 U2OS 48 306 Apoptosis +0.1859364301690428 8.677095759204528e-18 BR00117011 fludarabine final compound B06 U2OS 48 1148 Apoptosis +0.30026686999618757 1.2840964887727609e-17 BR00117011 RGB-286638 final compound K21 U2OS 48 430 Apoptosis +0.3024844930260832 1.5809879449051046e-17 BR00117011 BVT-948 final compound O16 U2OS 48 422 Apoptosis +0.189699705498962 1.8180639339068423e-17 BR00117012 PP-1 final compound A22 U2OS 48 1078 Apoptosis +0.18203174299360295 3.0262955756198343e-17 BR00117011 PP-1 final compound A22 U2OS 48 1156 Apoptosis +0.1401630988786952 3.2379856403445904e-17 BR00117011 AC-710 final compound I03 U2OS 48 1962 Apoptosis +0.22160105121247803 4.808662342898502e-17 BR00117012 BMS-536924 final compound B15 U2OS 48 766 Apoptosis +0.19880079946702198 7.13203370705484e-17 BR00117012 amlodipine final compound A03 U2OS 48 950 Apoptosis +0.1836055479940372 7.618558996679483e-17 BR00117011 lonafarnib final compound F22 U2OS 48 1112 Apoptosis +0.3684387053496562 8.665995014865723e-17 BR00117010 homoharringtonine final compound N15 U2OS 48 268 Apoptosis +0.3246500204666394 9.230119907338792e-17 BR00117013 7-hydroxystaurosporine final compound L04 U2OS 48 350 Apoptosis +0.32764063551208406 1.0044974837528905e-16 BR00117012 ganetespib final compound I17 U2OS 48 342 Apoptosis +0.293181105185318 1.427970711099635e-16 BR00117011 ixabepilone final compound J21 U2OS 48 424 Apoptosis 0.39173716662203806 3.7598203323059093e-146 BR00117012 L-Cystine final compound O08 U2OS 48 2124 Binuclear 0.4211146542909568 9.11018923494132e-117 BR00117012 AC-710 final compound I03 U2OS 48 1462 Binuclear 0.4868954030646236 9.703740143117272e-103 BR00117012 polydatin final compound K08 U2OS 48 950 Binuclear @@ -489,6 +4809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.672857932559425 2.3437186729609198e-58 BR00117013 AZD7762 final compound K11 U2OS 48 268 Binuclear 0.7708190345458705 9.50099521353711e-56 BR00117011 delanzomib final compound L11 U2OS 48 186 Binuclear 0.6966172611871498 1.367271573019167e-55 BR00117013 BVT-948 final compound B12 U2OS 48 236 Binuclear +0.3602642682656007 3.750243226940296e-55 BR00117012 amlodipine final compound A03 U2OS 48 950 Binuclear +0.29415385718725345 1.692662052283325e-54 BR00117012 quinine final compound A05 U2OS 48 1418 Binuclear +0.7421343537414966 1.7873322797828084e-52 BR00117011 AZD7762 final compound I05 U2OS 48 196 Binuclear +0.7884219806053482 6.03572626307448e-52 BR00117013 puromycin final compound C22 U2OS 48 164 Binuclear +0.5632183908045977 3.287898082601762e-51 BR00117012 ganetespib final compound M10 U2OS 48 348 Binuclear +0.6881349206349207 3.71186346784663e-51 BR00117010 delanzomib final compound L11 U2OS 48 224 Binuclear +0.7203460064228737 3.363156987685966e-50 BR00117012 delanzomib final compound L11 U2OS 48 196 Binuclear +0.7215300210224068 3.5560041310665147e-50 BR00117011 AZD7762 final compound K11 U2OS 48 198 Binuclear +0.6887725178047759 5.317325823968559e-50 BR00117012 BVT-948 final compound B12 U2OS 48 220 Binuclear +0.3737584118004159 1.324675049181293e-49 BR00117010 KU-60019 final compound I07 U2OS 48 786 Binuclear +0.6504065040650406 2.147204389185839e-49 BR00117010 AZD7762 final compound K11 U2OS 48 246 Binuclear +0.7007986991247788 1.411387421816821e-48 BR00117012 AZD7762 final compound K11 U2OS 48 206 Binuclear +0.5704983388704319 1.589790909688416e-45 BR00117011 ganetespib final compound I17 U2OS 48 300 Binuclear +0.5157549632687755 9.0382979618445e-45 BR00117013 ganetespib final compound M10 U2OS 48 364 Binuclear +0.8381016949152542 2.856693533010362e-44 BR00117011 ryuvidine final compound A14 U2OS 48 118 Binuclear +0.37475398991151904 3.683951332667408e-44 BR00117011 PF-431396 final compound L20 U2OS 48 696 Binuclear +0.5136137011137011 5.543799572512233e-43 BR00117012 7-hydroxystaurosporine final compound L04 U2OS 48 352 Binuclear +0.503357603371004 1.0980157332215334e-42 BR00117010 ganetespib final compound M10 U2OS 48 366 Binuclear +0.8125 1.1528210458564916e-42 BR00117012 puromycin final compound C22 U2OS 48 128 Binuclear +0.5151802656546489 1.338921479858425e-41 BR00117011 geldanamycin final compound L01 U2OS 48 340 Binuclear +0.4899103462192626 4.749262421446625e-41 BR00117011 azeliragon final compound C08 U2OS 48 372 Binuclear +0.8112542372881356 1.1555880406887765e-40 BR00117011 NSC-663284 final compound G06 U2OS 48 118 Binuclear +0.3410080156815639 1.4123086000368117e-40 BR00117013 KU-60019 final compound I07 U2OS 48 778 Binuclear +0.5326797385620915 4.383284805046782e-40 BR00117011 7-hydroxystaurosporine final compound L04 U2OS 48 306 Binuclear +0.47356140003954916 6.557456886815376e-40 BR00117010 azeliragon final compound C08 U2OS 48 390 Binuclear +0.6930512748669095 1.8801862194484858e-39 BR00117013 NSC-663284 final compound G06 U2OS 48 166 Binuclear +0.4109024970722678 2.7478568594932582e-39 BR00117012 epothilone-b final compound F07 U2OS 48 514 Binuclear +0.7829457364341085 4.834782757970872e-39 BR00117010 ponatinib final compound C20 U2OS 48 124 Binuclear +0.6847619047619048 7.640118149956394e-39 BR00117013 AZD7762 final compound I05 U2OS 48 168 Binuclear +0.21049949031600407 1.866501961370143e-38 BR00117011 AC-710 final compound I03 U2OS 48 1962 Binuclear +0.3458089730053422 3.2753497686591813e-38 BR00117012 PF-431396 final compound L20 U2OS 48 712 Binuclear +0.44287580830897333 3.452605048093941e-38 BR00117011 epothilone-b final compound F07 U2OS 48 426 Binuclear +0.48615090735434574 9.745841650236177e-38 BR00117011 ganetespib final compound M10 U2OS 48 348 Binuclear +0.517718715393134 1.5174895864821544e-37 BR00117010 GK921 final compound H24 U2OS 48 300 Binuclear +0.7108868060562364 1.0613724647161852e-36 BR00117012 NSC-632839 final compound M16 U2OS 48 152 Binuclear +0.7956841138659321 1.3600182712618512e-36 BR00117012 ponatinib final compound C20 U2OS 48 108 Binuclear +0.21718396637285536 2.5556691630075502e-36 BR00117011 PP-2 final compound J10 U2OS 48 1734 Binuclear +0.22428748451053285 5.613295614863075e-36 BR00117010 AC-710 final compound I03 U2OS 48 1614 Binuclear +0.4620793571069814 1.7823944021236926e-35 BR00117012 GK921 final compound H24 U2OS 48 362 Binuclear +0.47471924649381564 2.1377970187870994e-35 BR00117012 ganetespib final compound I17 U2OS 48 342 Binuclear +0.42823690225429123 2.28435359470312e-35 BR00117011 ixabepilone final compound J21 U2OS 48 424 Binuclear +0.39335219236209334 2.9336318678949216e-35 BR00117010 epothilone-b final compound F07 U2OS 48 504 Binuclear +0.6321879382889201 4.070890844919916e-35 BR00117013 NSC-632839 final compound M16 U2OS 48 184 Binuclear +0.6926406926406926 5.127319052218888e-35 BR00117010 NSC-663284 final compound G06 U2OS 48 154 Binuclear +0.75 1.6067972663252678e-34 BR00117013 ponatinib final compound C20 U2OS 48 120 Binuclear +0.4567219152854512 2.191391682362081e-34 BR00117012 NVP-HSP990 final compound E23 U2OS 48 360 Binuclear +0.30612593279032335 5.195359043963472e-34 BR00117011 KU-60019 final compound I07 U2OS 48 812 Binuclear +0.7281976744186046 5.3923394947966335e-34 BR00117010 AZD7762 final compound I05 U2OS 48 128 Binuclear +0.7058380819266745 3.629493437215552e-33 BR00117013 ryuvidine final compound A14 U2OS 48 142 Binuclear +0.7074660633484163 1.4129784038779223e-32 BR00117011 NSC-632839 final compound M16 U2OS 48 136 Binuclear +0.5876923076923077 3.398474472574068e-32 BR00117013 thiostrepton final compound B02 U2OS 48 200 Binuclear +0.44565307924239145 2.2258369812136844e-31 BR00117010 geldanamycin final compound L01 U2OS 48 346 Binuclear +0.43942693409742123 4.459034949851968e-31 BR00117013 7-hydroxystaurosporine final compound L04 U2OS 48 350 Binuclear +0.33830474770072083 8.810466334169517e-31 BR00117010 PF-431396 final compound L20 U2OS 48 596 Binuclear +0.4060857210513853 9.436316992698625e-31 BR00117011 BAX-channel-blocker final compound I19 U2OS 48 410 Binuclear +0.38425032175032175 5.967136351842638e-30 BR00117013 epothilone-b final compound F07 U2OS 48 444 Binuclear +0.7223140495867768 1.3410577706189e-29 BR00117012 AZD7762 final compound I05 U2OS 48 110 Binuclear +0.2995257136844004 2.1768991778337495e-29 BR00117013 PF-431396 final compound L20 U2OS 48 728 Binuclear +0.2800040742680868 3.266919967379399e-29 BR00117012 NVP-ADW742 final compound D16 U2OS 48 830 Binuclear +0.363265306122449 3.9535410392150356e-29 BR00117012 AMG900 final compound N09 U2OS 48 490 Binuclear +0.6406547392462886 1.7257563121871583e-28 BR00117011 BVT-948 final compound B12 U2OS 48 148 Binuclear +0.42573312510845046 2.9956275949434432e-28 BR00117013 GK921 final compound H24 U2OS 48 340 Binuclear +0.43355697234783896 3.813023126363906e-28 BR00117011 briciclib final compound H01 U2OS 48 328 Binuclear +0.4473684210526316 9.235594874691587e-28 BR00117010 colchicine final compound K17 U2OS 48 304 Binuclear +0.5828571428571429 1.0584133158257863e-27 BR00117011 UNC1999 final compound H19 U2OS 48 170 Binuclear +0.24246937524586715 1.7990154214377485e-27 BR00117013 FK-866 final compound D08 U2OS 48 1046 Binuclear +0.22142052779348895 2.0007889789553207e-27 BR00117011 polydatin final compound K08 U2OS 48 1254 Binuclear +0.5713264908405873 5.4879033283561774e-27 BR00117013 UNC1999 final compound H19 U2OS 48 172 Binuclear +0.5332739156268568 9.016380161252267e-27 BR00117012 UNC1999 final compound H19 U2OS 48 204 Binuclear +0.20338971503541253 1.6881101430366254e-26 BR00117010 PP-2 final compound J10 U2OS 48 1434 Binuclear +0.4377417874237755 1.8284518235859294e-26 BR00117010 briciclib final compound H01 U2OS 48 302 Binuclear +0.483739837398374 1.9007785863475516e-26 BR00117010 NSC-95397 final compound D03 U2OS 48 246 Binuclear +0.4479166666666667 2.1917351515813012e-26 BR00117013 NSC-95397 final compound D03 U2OS 48 288 Binuclear +0.20862469836982225 3.995418633575022e-26 BR00117012 PP-2 final compound J10 U2OS 48 1348 Binuclear +0.2246275743367559 4.074616088043772e-26 BR00117010 polydatin final compound K08 U2OS 48 1160 Binuclear +0.6639530228212999 4.284123927296333e-26 BR00117010 BVT-948 final compound B12 U2OS 48 118 Binuclear +0.41449755917841025 4.6373485457831054e-26 BR00117012 briciclib final compound H01 U2OS 48 330 Binuclear +0.42975978270095916 6.486676457439161e-26 BR00117010 PP-121 final compound B16 U2OS 48 308 Binuclear +0.2697090552884004 8.069642375769092e-26 BR00117010 NVP-ADW742 final compound D16 U2OS 48 794 Binuclear +0.4107142857142857 9.604097826324114e-26 BR00117012 ixabepilone final compound J21 U2OS 48 336 Binuclear +0.4605108631826189 1.101950094085976e-25 BR00117011 NVP-HSP990 final compound E23 U2OS 48 262 Binuclear +0.5093457943925234 1.2188022509947872e-25 BR00117013 buparlisib final compound L12 U2OS 48 214 Binuclear +0.7453900709219858 1.6463632054921052e-25 BR00117010 LDN-212854 final compound K01 U2OS 48 94 Binuclear +0.4391268453768454 1.8718657320727771e-25 BR00117010 7-hydroxystaurosporine final compound L04 U2OS 48 286 Binuclear +0.7851515151515152 2.523026192867836e-25 BR00117010 puromycin final compound C22 U2OS 48 88 Binuclear +0.4274640088593577 4.564697620623497e-25 BR00117010 ixabepilone final compound J21 U2OS 48 300 Binuclear +0.42953020134228187 4.713565926315615e-25 BR00117012 NSC-95397 final compound D03 U2OS 48 298 Binuclear +0.5432366999813769 7.559283549159425e-25 BR00117012 thiostrepton final compound B02 U2OS 48 178 Binuclear +0.5532773109243697 8.470100285792098e-25 BR00117011 thiostrepton final compound B02 U2OS 48 170 Binuclear +0.46921487603305784 1.2323638865867085e-24 BR00117013 CYT-997 final compound C09 U2OS 48 240 Binuclear 0.5197914699104681 7.948957725080473e-64 BR00117012 epothilone-b final compound F07 U2OS 48 514 Elongated 0.5528167436023843 4.963714650336185e-60 BR00117011 ixabepilone final compound J21 U2OS 48 424 Elongated 0.4983969825553984 2.4781033788516682e-57 BR00117010 epothilone-b final compound F07 U2OS 48 504 Elongated @@ -499,6 +4909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2863281428686831 3.424650602803198e-52 BR00117010 PP-2 final compound J10 U2OS 48 1434 Elongated 0.4816326530612245 7.633154788690861e-52 BR00117012 AMG900 final compound N09 U2OS 48 490 Elongated 0.29931907685387665 1.2294000833450211e-51 BR00117013 PP-2 final compound J10 U2OS 48 1292 Elongated +0.5017696267696268 1.5969935685149942e-51 BR00117013 epothilone-b final compound F07 U2OS 48 444 Elongated +0.2588802672271191 1.6354518756302136e-51 BR00117011 PP-2 final compound J10 U2OS 48 1734 Elongated +0.26724874162975953 3.9311372145447335e-46 BR00117010 NVS-PAK1-1 final compound N14 U2OS 48 1456 Elongated +0.3761969734557182 1.6689261768686995e-44 BR00117011 PF-431396 final compound L20 U2OS 48 696 Elongated +0.40204053962443226 1.1924673061712532e-43 BR00117010 PF-431396 final compound L20 U2OS 48 596 Elongated +0.4412153456087119 2.403945926496667e-43 BR00117010 KG-5 final compound C13 U2OS 48 490 Elongated +0.3655073514348299 9.815613661882108e-43 BR00117012 PF-431396 final compound L20 U2OS 48 712 Elongated +0.26227472597572 2.3123823548505046e-41 BR00117012 PP-2 final compound J10 U2OS 48 1348 Elongated +0.5439645625692138 3.427026002325302e-41 BR00117010 ixabepilone final compound J21 U2OS 48 300 Elongated +0.23681715941478995 1.066020222095507e-39 BR00117011 NVS-PAK1-1 final compound N14 U2OS 48 1590 Elongated +0.23925831202046036 1.093669385589739e-39 BR00117013 NVS-PAK1-1 final compound N14 U2OS 48 1560 Elongated +0.2527727860902923 3.594103546606548e-37 BR00117012 NVS-PAK1-1 final compound N14 U2OS 48 1306 Elongated +0.5294117647058824 3.2518144673209257e-35 BR00117010 oxibendazole final compound M19 U2OS 48 272 Elongated +0.4934210526315789 5.84964211889935e-34 BR00117010 colchicine final compound K17 U2OS 48 304 Elongated +0.4719719996315741 8.90422401660183e-34 BR00117012 briciclib final compound H01 U2OS 48 330 Elongated +0.4375 2.0946880013791946e-33 BR00117011 KG-5 final compound C13 U2OS 48 384 Elongated +0.3164526991476376 7.282170745320076e-33 BR00117013 PF-431396 final compound L20 U2OS 48 728 Elongated +0.21825007541248728 1.225171402904764e-32 BR00117012 simvastatin final compound N24 U2OS 48 1538 Elongated +0.22463736334423948 3.2423304129718354e-32 BR00117012 RKI-1447 final compound J04 U2OS 48 1434 Elongated +0.4523809523809524 2.3732137493651904e-31 BR00117012 ixabepilone final compound J21 U2OS 48 336 Elongated +0.2201287600480122 3.8198528297907954e-31 BR00117013 PP-1 final compound A22 U2OS 48 1444 Elongated +0.4866187050359712 2.809799646294545e-30 BR00117012 oxibendazole final compound M19 U2OS 48 278 Elongated +0.24098985264958594 4.848731363004994e-30 BR00117011 PP-1 final compound A22 U2OS 48 1156 Elongated +0.466864124398371 1.3254217616974311e-29 BR00117013 colchicine final compound K17 U2OS 48 296 Elongated +0.4349112426035503 4.286296501624144e-29 BR00117013 ixabepilone final compound J21 U2OS 48 338 Elongated +0.21062751470133087 2.156765957989951e-28 BR00117010 PP-1 final compound A22 U2OS 48 1440 Elongated +0.476521492410271 7.132761011606395e-28 BR00117012 colchicine final compound K17 U2OS 48 266 Elongated +0.44484514676633224 1.1657949306515524e-27 BR00117010 briciclib final compound H01 U2OS 48 302 Elongated +0.22932073476345477 3.8170179268942226e-27 BR00117011 AZ191 final compound I18 U2OS 48 1154 Elongated +0.2155918035641725 1.053433895901661e-26 BR00117013 RKI-1447 final compound J04 U2OS 48 1288 Elongated +0.3864664422470019 1.819754304657632e-26 BR00117013 KG-5 final compound C13 U2OS 48 388 Elongated +0.1914577433046325 2.2350005959478473e-26 BR00117010 RKI-1447 final compound J04 U2OS 48 1612 Elongated +0.4579925650557621 6.623276279249738e-26 BR00117010 CYT-997 final compound E06 U2OS 48 270 Elongated +0.4775619791485059 3.438759058092462e-25 BR00117012 CYT-997 final compound E06 U2OS 48 238 Elongated +0.21393841166936792 3.9060342234529647e-25 BR00117011 simvastatin final compound N24 U2OS 48 1234 Elongated +0.3885737258230223 4.202399877590987e-25 BR00117010 ganetespib final compound M10 U2OS 48 366 Elongated +0.4247840531561462 4.951715049488604e-25 BR00117011 ganetespib final compound I17 U2OS 48 300 Elongated +0.4730027548209366 6.58675896424954e-25 BR00117013 CYT-997 final compound C09 U2OS 48 240 Elongated +0.39655172413793105 8.054112244608638e-25 BR00117012 ganetespib final compound M10 U2OS 48 348 Elongated +0.22646750487961323 1.174306792207058e-24 BR00117012 PP-1 final compound A22 U2OS 48 1078 Elongated +0.3832789908770543 1.6816494453695066e-23 BR00117011 ganetespib final compound M10 U2OS 48 348 Elongated +0.37499241090401314 2.277900807912047e-23 BR00117013 ganetespib final compound M10 U2OS 48 364 Elongated +0.38642401242021734 2.3239834882090873e-23 BR00117011 geldanamycin final compound L01 U2OS 48 340 Elongated +0.48598130841121495 2.828165068829998e-23 BR00117013 buparlisib final compound L12 U2OS 48 214 Elongated +0.5016575157981975 2.976253406382882e-23 BR00117012 delanzomib final compound L11 U2OS 48 196 Elongated +0.42295065533919757 3.833522763520612e-23 BR00117010 CYT-997 final compound C09 U2OS 48 282 Elongated +0.41373565346168084 4.742712574108153e-23 BR00117013 oxibendazole final compound M19 U2OS 48 296 Elongated +0.36152360748476936 6.03841639757984e-23 BR00117012 KG-5 final compound C13 U2OS 48 384 Elongated +0.45121951219512196 6.206541809688896e-23 BR00117010 AZD7762 final compound K11 U2OS 48 246 Elongated +0.609375 1.7461918487868324e-22 BR00117012 puromycin final compound C22 U2OS 48 128 Elongated +0.17884559487706891 2.635389141096968e-22 BR00117011 RKI-1447 final compound J04 U2OS 48 1558 Elongated +0.4585812356979405 2.821310794209462e-22 BR00117011 oxibendazole final compound M19 U2OS 48 230 Elongated +0.4126760563380282 4.147242484305125e-22 BR00117013 briciclib final compound H01 U2OS 48 284 Elongated +0.5585796683489546 5.028918215184863e-22 BR00117012 NSC-632839 final compound M16 U2OS 48 152 Elongated +0.31251612903225806 5.44830542621789e-22 BR00117011 GSK1070916 final compound C04 U2OS 48 500 Elongated +0.3380281690140845 5.826635489309737e-22 BR00117010 GSK1070916 final compound C04 U2OS 48 426 Elongated +0.4522120518688024 1.174811271256768e-21 BR00117011 colchicine final compound K17 U2OS 48 230 Elongated +0.24346437106764865 1.311761682207233e-21 BR00117011 KU-60019 final compound I07 U2OS 48 812 Elongated +0.3902198125499096 2.191314296561758e-21 BR00117011 UNC2025 final compound N06 U2OS 48 308 Elongated +0.49996896145012104 4.382498012999934e-21 BR00117012 thiostrepton final compound B02 U2OS 48 178 Elongated +0.24497823655005593 4.418106094431817e-21 BR00117013 KU-60019 final compound I07 U2OS 48 778 Elongated +0.6843971631205674 4.965001195230845e-21 BR00117010 LDN-212854 final compound K01 U2OS 48 94 Elongated +0.4526183493925429 8.609736465052531e-21 BR00117012 BVT-948 final compound B12 U2OS 48 220 Elongated +0.23096894712618785 1.2716950350869428e-20 BR00117010 AZ191 final compound I18 U2OS 48 860 Elongated +0.38750830564784056 1.4658322107205443e-20 BR00117010 GK921 final compound H24 U2OS 48 300 Elongated +0.44345238095238093 1.5185338055683273e-20 BR00117010 delanzomib final compound L11 U2OS 48 224 Elongated +0.5152806347340582 1.5282940660514648e-20 BR00117013 puromycin final compound C22 U2OS 48 164 Elongated +0.4832418210935713 1.9417076651400858e-20 BR00117011 delanzomib final compound L11 U2OS 48 186 Elongated +0.3493752187875744 2.7018313030493223e-20 BR00117012 GK921 final compound H24 U2OS 48 362 Elongated +0.4308914261399901 2.8482470425487685e-20 BR00117013 BVT-948 final compound B12 U2OS 48 236 Elongated +0.39068570318570317 3.414263675666095e-20 BR00117012 geldanamycin final compound L01 U2OS 48 288 Elongated +0.39964172080960403 5.69442124934855e-20 BR00117011 CYT-997 final compound C09 U2OS 48 274 Elongated +0.4066059894304169 5.944715776895589e-20 BR00117012 UNC2025 final compound N06 U2OS 48 262 Elongated +0.4664102564102564 6.028708343446963e-20 BR00117013 thiostrepton final compound B02 U2OS 48 200 Elongated +0.15064186990188544 2.04339059298436e-19 BR00117012 dexamethasone final compound O02 U2OS 48 1916 Elongated +0.5953474135292317 2.237515316256825e-19 BR00117012 ponatinib final compound C20 U2OS 48 108 Elongated +0.35051889856907265 2.4286727080998248e-19 BR00117010 geldanamycin final compound L01 U2OS 48 346 Elongated +0.15247670460886062 2.980081344382104e-19 BR00117010 SB-203580 final compound L08 U2OS 48 1854 Elongated +0.5515837104072399 3.3490863520862295e-19 BR00117011 NSC-632839 final compound M16 U2OS 48 136 Elongated +0.4603528911564626 3.5299546859395535e-19 BR00117011 AZD7762 final compound I05 U2OS 48 196 Elongated +0.3572725924827637 4.648499956184915e-19 BR00117011 briciclib final compound H01 U2OS 48 328 Elongated +0.3418079096045198 9.974629814464727e-19 BR00117011 GK921 final compound H24 U2OS 48 354 Elongated +0.3899944720840243 1.0202426647909546e-18 BR00117013 AZD7762 final compound K11 U2OS 48 268 Elongated +0.20704075425790755 1.4597719822335107e-18 BR00117013 polydatin final compound K08 U2OS 48 960 Elongated +0.1882960413080895 1.822162183251977e-18 BR00117010 polydatin final compound K08 U2OS 48 1160 Elongated +0.38313516468498016 2.191773764727388e-18 BR00117013 delanzomib final compound L11 U2OS 48 270 Elongated +0.43075211392968404 2.8459492322443047e-18 BR00117010 buparlisib final compound D11 U2OS 48 214 Elongated +0.22494542824298316 5.79010955558964e-18 BR00117010 KU-60019 final compound I07 U2OS 48 786 Elongated +0.5034013605442177 6.500288477937595e-18 BR00117010 NSC-663284 final compound G06 U2OS 48 154 Elongated +0.5685950413223141 9.52810520321331e-18 BR00117012 AZD7762 final compound I05 U2OS 48 110 Elongated 0.26682962739083443 3.830367363782256e-67 BR00117012 L-Cystine final compound O08 U2OS 48 2124 Grape 0.4441789215686274 7.623674674117968e-46 BR00117013 fludarabine-phosphate final compound N12 U2OS 48 510 Grape 0.32133688652009773 8.66835978911451e-44 BR00117012 polydatin final compound K08 U2OS 48 950 Grape @@ -509,6 +5009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2222763850819502 4.5611921553284046e-38 BR00117011 PP-2 final compound J10 U2OS 48 1734 Grape 0.25271196903067744 1.0167117048859095e-36 BR00117013 PP-2 final compound J10 U2OS 48 1292 Grape 0.2993421052631579 1.908530064822843e-36 BR00117012 deferasirox final compound L14 U2OS 48 912 Grape +0.20671563483735572 4.815717532781646e-36 BR00117011 SB-203580 final compound L08 U2OS 48 1906 Grape +0.23203897763516085 2.0255403170324423e-34 BR00117010 PP-2 final compound J10 U2OS 48 1434 Grape +0.23905937577675956 3.097548892953634e-34 BR00117012 PP-2 final compound J10 U2OS 48 1348 Grape +0.32071346470989986 3.9770670824497345e-32 BR00117013 BMS-536924 final compound B15 U2OS 48 694 Grape +0.3479020979020979 4.204982488590625e-31 BR00117011 fludarabine-phosphate final compound N12 U2OS 48 572 Grape +0.24365244228144103 1.094212307278517e-30 BR00117010 polydatin final compound K08 U2OS 48 1160 Grape +0.3058357511161889 1.2643909172065377e-30 BR00117013 PF-431396 final compound L20 U2OS 48 728 Grape +0.26523070907194995 3.703530267310229e-30 BR00117013 polydatin final compound K08 U2OS 48 960 Grape +0.1832627118644068 4.112043087410816e-28 BR00117013 SB-203580 final compound L08 U2OS 48 1888 Grape +0.2561126318099396 2.940996566779811e-27 BR00117011 deferasirox final compound L14 U2OS 48 930 Grape +0.201236323938387 1.1953512228446815e-25 BR00117012 quinine final compound A05 U2OS 48 1418 Grape +0.2000502910742115 1.3776099428571272e-25 BR00117012 RKI-1447 final compound J04 U2OS 48 1434 Grape +0.17452063938629106 2.1482268180661023e-25 BR00117012 PETCM final compound I04 U2OS 48 1874 Grape +0.2581794460056202 2.7746411857029824e-25 BR00117013 deferasirox final compound L14 U2OS 48 846 Grape +0.18888796650973044 3.132721112968179e-25 BR00117011 lonafarnib final compound J06 U2OS 48 1590 Grape +0.27840112201963535 9.566300445701682e-25 BR00117012 PF-431396 final compound L20 U2OS 48 712 Grape +0.19589091680938356 1.3954495190802785e-24 BR00117013 lonafarnib final compound J06 U2OS 48 1434 Grape +0.19086021505376344 4.201569114238658e-24 BR00117012 SB-203580 final compound L08 U2OS 48 1488 Grape +0.18645161290322582 5.881006974552026e-24 BR00117010 lonafarnib final compound J06 U2OS 48 1550 Grape +0.20686734074561913 9.64753053756217e-24 BR00117013 lonafarnib final compound F22 U2OS 48 1244 Grape +0.2725998511535599 2.3569736110688646e-23 BR00117011 PF-431396 final compound L20 U2OS 48 696 Grape +0.1789200340287275 4.87154085966939e-23 BR00117010 RKI-1447 final compound J04 U2OS 48 1612 Grape +0.20734809369621657 1.7704354864560532e-22 BR00117010 lonafarnib final compound F22 U2OS 48 1172 Grape +0.23487137727370838 2.1448068907724688e-22 BR00117010 deferasirox final compound L14 U2OS 48 904 Grape +0.1989059928357053 3.184953131408458e-22 BR00117011 polydatin final compound K08 U2OS 48 1254 Grape +0.31020408163265306 3.19014334135982e-21 BR00117012 AMG900 final compound N09 U2OS 48 490 Grape +0.2462499360057339 6.994527635690902e-21 BR00117012 BMS-536924 final compound B15 U2OS 48 766 Grape +0.20411886706850735 1.0554447517033201e-20 BR00117011 lonafarnib final compound F22 U2OS 48 1112 Grape +0.24460188933873145 4.891039984420534e-20 BR00117011 BMS-536924 final compound B15 U2OS 48 744 Grape +0.2921184975640421 2.063243626048795e-19 BR00117010 epothilone-b final compound F07 U2OS 48 504 Grape +0.2173953078127196 2.662297567847827e-19 BR00117010 JTE-607 final compound C14 U2OS 48 908 Grape +0.26734910627528075 2.9501784785966403e-19 BR00117010 PF-431396 final compound L20 U2OS 48 596 Grape +0.2909477626035756 4.929890322861152e-19 BR00117012 AVL-292 final compound A24 U2OS 48 494 Grape +0.24333755341034974 5.520675414208061e-19 BR00117012 JTE-607 final compound C14 U2OS 48 710 Grape +0.15948803625641333 8.054218016788044e-18 BR00117011 RKI-1447 final compound J04 U2OS 48 1558 Grape +0.17474507072231574 1.2865695213978846e-17 BR00117013 RKI-1447 final compound J04 U2OS 48 1288 Grape +0.22394738492101468 1.5135022954109574e-17 BR00117013 KU-60019 final compound I07 U2OS 48 778 Grape +0.27371543086172345 4.634299163258788e-17 BR00117012 danusertib final compound E05 U2OS 48 500 Grape +0.27165354330708663 6.766317696897325e-17 BR00117010 AMG900 final compound N09 U2OS 48 508 Grape +0.28555341055341055 1.4385682069923774e-16 BR00117013 epothilone-b final compound F07 U2OS 48 444 Grape +0.4248717948717949 1.4539881462869e-16 BR00117013 thiostrepton final compound B02 U2OS 48 200 Grape +0.23423423423423423 1.9748146753418836e-16 BR00117013 JTE-607 final compound C14 U2OS 48 666 Grape +0.15770617209739513 3.58550838147553e-16 BR00117013 PP-1 final compound A22 U2OS 48 1444 Grape +0.20984733941374434 4.183786178694471e-16 BR00117011 JTE-607 final compound C14 U2OS 48 812 Grape +0.2855510240666876 9.800873052071523e-16 BR00117011 ixabepilone final compound J21 U2OS 48 424 Grape +0.1732870177915083 1.3434089446608656e-15 BR00117011 PP-1 final compound A22 U2OS 48 1156 Grape +0.28276419523429885 1.481005488168094e-15 BR00117011 epothilone-b final compound F07 U2OS 48 426 Grape +0.17935311284046693 6.626251304756744e-15 BR00117012 lonafarnib final compound F22 U2OS 48 1028 Grape +0.1512341380377592 7.949808586373494e-15 BR00117010 PP-1 final compound A22 U2OS 48 1440 Grape +0.15543486354356637 1.2556190277753178e-14 BR00117012 fludarabine final compound B06 U2OS 48 1342 Grape +0.2903091060985798 1.3118340692183618e-14 BR00117010 AVL-292 final compound A24 U2OS 48 380 Grape +0.26851851851851855 4.1914085365599055e-14 BR00117013 AVL-292 final compound A24 U2OS 48 432 Grape +0.2992806500025876 5.216681814439671e-14 BR00117012 azeliragon final compound C08 U2OS 48 342 Grape +0.27608040201005024 5.765306865174268e-14 BR00117010 RGB-286638 final compound K21 U2OS 48 400 Grape +0.22521482130151607 6.461731811319559e-14 BR00117013 AMG900 final compound N09 U2OS 48 604 Grape +0.2495781204538842 7.436271002671889e-14 BR00117010 KG-5 final compound C13 U2OS 48 490 Grape +0.17024560015108323 7.621522873044181e-14 BR00117010 WH-4-023 final compound A18 U2OS 48 1054 Grape +0.26338434725777465 1.2939303273112765e-13 BR00117011 RGB-286638 final compound K21 U2OS 48 430 Grape +0.287354205033763 1.3188574968928034e-13 BR00117012 NVP-HSP990 final compound E23 U2OS 48 360 Grape +0.400148985039419 1.8742251006141752e-13 BR00117012 thiostrepton final compound B02 U2OS 48 178 Grape +0.15993073582698336 2.1217556327466237e-13 BR00117011 AZ191 final compound I18 U2OS 48 1154 Grape +0.23255387250005097 2.422058347132987e-13 BR00117011 AMG900 final compound N09 U2OS 48 542 Grape +0.3064680417621594 2.683636500992347e-13 BR00117010 PP-121 final compound B16 U2OS 48 308 Grape +0.12882400962447366 5.854873059514573e-13 BR00117012 A205804 final compound M06 U2OS 48 1728 Grape +0.12020937780960944 1.5350922825709525e-12 BR00117012 dexamethasone final compound O02 U2OS 48 1916 Grape +0.2002849635952471 1.925172268656997e-12 BR00117012 SKLB1002 final compound P17 U2OS 48 678 Grape +0.1198918657775435 1.960963444097654e-12 BR00117012 trazodone final compound G08 U2OS 48 1906 Grape +0.13805029489114704 2.2020540839704682e-12 BR00117013 gabapentin-enacarbil final compound A01 U2OS 48 1432 Grape +0.23010086509765404 2.2214319064601057e-12 BR00117012 epothilone-b final compound F07 U2OS 48 514 Grape +0.28421795289265167 2.4086388607326707e-12 BR00117011 AVL-292 final compound A24 U2OS 48 332 Grape +0.2748640248640249 2.6920568705435107e-12 BR00117013 RGB-286638 final compound K21 U2OS 48 352 Grape +0.4486607142857143 4.977098128989882e-12 BR00117012 CYT-997 final compound C09 U2OS 48 126 Grape +0.1552855004793401 7.658893346880487e-12 BR00117012 PP-1 final compound A22 U2OS 48 1078 Grape +0.17841291518314392 9.449543084590528e-12 BR00117011 KU-60019 final compound I07 U2OS 48 812 Grape +0.11389149449371407 1.0881363454755469e-11 BR00117010 KU-55933 final compound J16 U2OS 48 1986 Grape +0.12355426983181599 1.2183466866048095e-11 BR00117013 AC-710 final compound I03 U2OS 48 1680 Grape +0.13255701957158267 1.652637183752806e-11 BR00117012 lonafarnib final compound J06 U2OS 48 1442 Grape +0.16567745503258438 1.8939905409168678e-11 BR00117013 arcyriaflavin-a final compound B04 U2OS 48 914 Grape +0.19095988911028328 2.2737514178264783e-11 BR00117011 SKLB1002 final compound P17 U2OS 48 680 Grape +0.11725436880077217 3.341825163127307e-11 BR00117013 LY2109761 final compound M02 U2OS 48 1788 Grape +0.13361932812566696 4.1426398885402975e-11 BR00117012 AZD1283 final compound P19 U2OS 48 1370 Grape +0.1531791907514451 4.863745325676546e-11 BR00117011 arcyriaflavin-a final compound B04 U2OS 48 1038 Grape +0.11535440604298978 5.961765963441455e-11 BR00117010 sotrastaurin final compound K12 U2OS 48 1814 Grape +0.1280503121162744 6.446548970713664e-11 BR00117012 AC-710 final compound I03 U2OS 48 1462 Grape +0.25794807044807044 7.141801201318107e-11 BR00117013 PP-121 final compound B16 U2OS 48 352 Grape +0.16824862080336533 1.273526136106511e-10 BR00117013 WH-4-023 final compound A18 U2OS 48 822 Grape +0.25966879420389855 1.5483938344428304e-10 BR00117011 geldanamycin final compound L01 U2OS 48 340 Grape +0.2745293466223699 1.799474525883355e-10 BR00117011 ganetespib final compound I17 U2OS 48 300 Grape +0.2454630788485607 1.9296764698253025e-10 BR00117012 RGB-286638 final compound K21 U2OS 48 374 Grape +0.194785320359195 2.8349886771730694e-10 BR00117010 SKLB1002 final compound P17 U2OS 48 590 Grape 0.6285082906149938 1.4113862754088088e-135 BR00117013 PF-431396 final compound L20 U2OS 48 728 Hole 0.6472045293701345 4.507468122653625e-125 BR00117010 danusertib final compound E05 U2OS 48 628 Hole 0.6146448358554536 4.518852618694611e-123 BR00117011 PF-431396 final compound L20 U2OS 48 696 Hole @@ -519,6 +5109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.6407447237531926 9.325388264193103e-101 BR00117011 danusertib final compound E05 U2OS 48 516 Hole 0.6437007874015748 2.1213531545421885e-99 BR00117010 AMG900 final compound N09 U2OS 48 508 Hole 0.6110732165609194 6.274488567712449e-98 BR00117010 danusertib final compound N18 U2OS 48 556 Hole +0.5881974103450613 6.8926682579908974e-96 BR00117010 PF-431396 final compound L20 U2OS 48 596 Hole +0.6290514573342856 7.587866317581887e-91 BR00117012 danusertib final compound N18 U2OS 48 484 Hole +0.6130130553207477 2.3545455333503752e-89 BR00117013 danusertib final compound E05 U2OS 48 504 Hole +0.6055551102204408 1.1063462377712364e-85 BR00117012 danusertib final compound E05 U2OS 48 500 Hole +0.57745658325473 1.2339012270701733e-83 BR00117011 danusertib final compound N18 U2OS 48 536 Hole +0.5472027972027972 5.621780645462528e-79 BR00117011 fludarabine-phosphate final compound N12 U2OS 48 572 Hole +0.531893642161887 4.789938827161097e-72 BR00117012 fludarabine-phosphate final compound N12 U2OS 48 554 Hole +0.5635821580094026 1.1349239504959739e-67 BR00117013 danusertib final compound N18 U2OS 48 456 Hole +0.5321939336790822 7.328908177759137e-66 BR00117010 epothilone-b final compound F07 U2OS 48 504 Hole +0.5693927717246877 4.3037317792482074e-64 BR00117011 epothilone-b final compound F07 U2OS 48 426 Hole +0.516081749839447 3.4962687794538854e-63 BR00117010 fludarabine-phosphate final compound N12 U2OS 48 514 Hole +0.5130131740196079 4.6445718403208364e-62 BR00117013 fludarabine-phosphate final compound N12 U2OS 48 510 Hole +0.4945675215096222 2.9062123640940913e-55 BR00117010 KG-5 final compound C13 U2OS 48 490 Hole +0.48099429564428997 2.5154194390746644e-54 BR00117012 epothilone-b final compound F07 U2OS 48 514 Hole +0.4840733590733591 7.925762308670527e-48 BR00117013 epothilone-b final compound F07 U2OS 48 444 Hole +0.2892901655884622 2.9812762617559098e-43 BR00117010 polydatin final compound K08 U2OS 48 1160 Hole +0.4295483870967742 9.999894238863828e-42 BR00117011 GSK1070916 final compound C04 U2OS 48 500 Hole +0.652051282051282 2.248623520673729e-40 BR00117013 thiostrepton final compound B02 U2OS 48 200 Hole +0.4629297214969539 8.996383445966846e-38 BR00117012 KG-5 final compound C13 U2OS 48 384 Hole +0.34616105236097133 1.3509805125599862e-36 BR00117012 SKLB1002 final compound P17 U2OS 48 678 Hole +0.2841088807785888 9.753671743180759e-35 BR00117013 polydatin final compound K08 U2OS 48 960 Hole +0.4296875 3.3823018940661333e-32 BR00117011 KG-5 final compound C13 U2OS 48 384 Hole +0.28132664874516805 5.150257889496747e-32 BR00117010 deferasirox final compound L14 U2OS 48 904 Hole +0.26879413724183876 9.898313463735925e-31 BR00117012 polydatin final compound K08 U2OS 48 950 Hole +0.2741228070175439 1.4827284805441743e-30 BR00117012 deferasirox final compound L14 U2OS 48 912 Hole +0.4127130233536714 2.9886929995038823e-30 BR00117013 KG-5 final compound C13 U2OS 48 388 Hole +0.281086912886391 4.798081411150245e-30 BR00117013 deferasirox final compound L14 U2OS 48 846 Hole +0.19016316073354908 9.053730787642998e-30 BR00117010 SB-203580 final compound L08 U2OS 48 1854 Hole +0.5918430690918121 1.1599350251674785e-29 BR00117012 thiostrepton final compound B02 U2OS 48 178 Hole +0.38836104513064135 5.944046299577083e-29 BR00117011 ixabepilone final compound J21 U2OS 48 424 Hole +0.3714071592311762 9.373220176646851e-27 BR00117012 GSK1070916 final compound C04 U2OS 48 424 Hole +0.3775268514610009 1.1361934260370417e-26 BR00117013 GSK1070916 final compound C04 U2OS 48 414 Hole +0.2774869109947644 2.7019664829626194e-26 BR00117010 BMS-536924 final compound B15 U2OS 48 764 Hole +0.24885485603409446 6.951600255074374e-26 BR00117011 deferasirox final compound L14 U2OS 48 930 Hole +0.36619718309859156 8.626903753014531e-26 BR00117010 GSK1070916 final compound C04 U2OS 48 426 Hole +0.4107142857142857 9.604097826324114e-26 BR00117012 ixabepilone final compound J21 U2OS 48 336 Hole +0.3067940981145151 5.357901565666761e-25 BR00117010 SKLB1002 final compound P17 U2OS 48 590 Hole +0.21080274750192357 6.333377044092567e-25 BR00117011 polydatin final compound K08 U2OS 48 1254 Hole +0.19149826611423693 1.7604805972936458e-23 BR00117010 PP-2 final compound J10 U2OS 48 1434 Hole +0.41373200442967883 1.78335386651802e-23 BR00117010 ixabepilone final compound J21 U2OS 48 300 Hole +0.45429402170058863 1.0239479626521856e-22 BR00117013 BVT-948 final compound B12 U2OS 48 236 Hole +0.17231699707876003 3.3384432573042307e-22 BR00117013 AC-710 final compound I03 U2OS 48 1680 Hole +0.26870830806549423 3.449660277303354e-22 BR00117011 SKLB1002 final compound P17 U2OS 48 680 Hole +0.32665194996320823 7.869230712958815e-22 BR00117013 SKLB1002 final compound P17 U2OS 48 450 Hole +0.16574234638835836 2.6677580507347597e-21 BR00117011 PP-2 final compound J10 U2OS 48 1734 Hole +0.1874338055436086 4.9269741371058415e-21 BR00117012 fludarabine final compound B06 U2OS 48 1342 Hole +0.18950048090496266 8.578796125977805e-21 BR00117013 PP-2 final compound J10 U2OS 48 1292 Hole +0.17225806451612904 1.7105302311589645e-20 BR00117010 lonafarnib final compound J06 U2OS 48 1550 Hole +0.16806011803817858 4.735209733637169e-20 BR00117011 lonafarnib final compound J06 U2OS 48 1590 Hole +0.15057712486883526 2.924977802561088e-19 BR00117011 SB-203580 final compound L08 U2OS 48 1906 Hole +0.2396391101824039 3.1293322616850395e-19 BR00117011 BMS-536924 final compound B15 U2OS 48 744 Hole +0.23199372002935204 1.202795223963926e-18 BR00117012 BMS-536924 final compound B15 U2OS 48 766 Hole +0.16209248382615826 2.096603204433073e-18 BR00117011 RKI-1447 final compound J04 U2OS 48 1558 Hole +0.4894210990302674 2.100978430783242e-18 BR00117013 puromycin final compound C22 U2OS 48 164 Hole +0.14671610169491525 3.9083901535325616e-18 BR00117013 SB-203580 final compound L08 U2OS 48 1888 Hole +0.5236928104575164 4.300910310129936e-18 BR00117010 thiostrepton final compound B02 U2OS 48 144 Hole +0.45698924731182794 5.496415354555053e-18 BR00117013 NSC-632839 final compound M16 U2OS 48 184 Hole +0.17228389861266616 6.473044697491304e-18 BR00117012 PP-2 final compound J10 U2OS 48 1348 Hole +0.16641321698878522 7.620191891111862e-18 BR00117013 lonafarnib final compound J06 U2OS 48 1434 Hole +0.34023668639053256 9.79346879956317e-18 BR00117013 ixabepilone final compound J21 U2OS 48 338 Hole +0.23678182938814946 1.3771176451586119e-17 BR00117013 BMS-536924 final compound B15 U2OS 48 694 Hole +0.14118246687054026 1.83794874297391e-17 BR00117011 AC-710 final compound I03 U2OS 48 1962 Hole +0.2674933174933175 8.706072115888931e-17 BR00117011 menadione final compound M12 U2OS 48 518 Hole +0.2118958201238843 2.0939401962757034e-16 BR00117011 JTE-607 final compound C14 U2OS 48 812 Hole +0.416614854847195 2.1198977530236182e-16 BR00117012 AZD7762 final compound K11 U2OS 48 206 Hole +0.3984920634920635 2.2045630631878563e-16 BR00117010 delanzomib final compound L11 U2OS 48 224 Hole +0.3637110980622431 7.921889202599717e-16 BR00117012 UNC2025 final compound N06 U2OS 48 262 Hole +0.22972972972972974 8.142297131040707e-16 BR00117013 JTE-607 final compound C14 U2OS 48 666 Hole +0.1283404076315815 9.76707628617633e-16 BR00117012 L-Cystine final compound O08 U2OS 48 2124 Hole +0.21985678113625573 1.3552301535193427e-15 BR00117012 JTE-607 final compound C14 U2OS 48 710 Hole +0.2992085081951526 1.4759363759027954e-15 BR00117012 BI-2536 final compound E21 U2OS 48 382 Hole +0.33215651662253604 1.5220784999900919e-15 BR00117011 UNC2025 final compound N06 U2OS 48 308 Hole +0.3113830613830614 1.651938408716797e-15 BR00117012 cycloheximide final compound K14 U2OS 48 352 Hole +0.15711770283082757 2.4678176507457442e-14 BR00117013 RKI-1447 final compound J04 U2OS 48 1288 Hole +0.14857503749901319 2.756133852373111e-14 BR00117012 RKI-1447 final compound J04 U2OS 48 1434 Hole +0.31237693389592125 3.3758879268427725e-14 BR00117010 BI-2536 final compound E21 U2OS 48 316 Hole +0.1625565181879175 5.211069863020103e-14 BR00117010 lonafarnib final compound F22 U2OS 48 1172 Hole +0.29499155321474707 7.347218331089126e-14 BR00117013 BI-2536 final compound I14 U2OS 48 348 Hole +0.15694804943245652 8.189111636446945e-14 BR00117013 lonafarnib final compound F22 U2OS 48 1244 Hole +0.37383177570093457 1.0582776613609869e-13 BR00117013 buparlisib final compound L12 U2OS 48 214 Hole +0.16669659799403633 1.1914176568626894e-13 BR00117011 NNC-55-0396 final compound A16 U2OS 48 1088 Hole +0.2976190476190476 1.5768902750994659e-13 BR00117012 BI-2536 final compound I14 U2OS 48 336 Hole +0.14180107526881722 1.8511285000309161e-13 BR00117012 SB-203580 final compound L08 U2OS 48 1488 Hole +0.3249861802100608 3.9045468548624424e-13 BR00117013 AZD7762 final compound K11 U2OS 48 268 Hole +0.12646966811545343 4.228634474415118e-13 BR00117010 sotrastaurin final compound K12 U2OS 48 1814 Hole +0.34228650137741046 4.550047399434118e-13 BR00117013 CYT-997 final compound C09 U2OS 48 240 Hole +0.19572340425531914 4.568783710605013e-13 BR00117012 aminopurvalanol-a final compound K03 U2OS 48 750 Hole +0.4320475847152127 4.758817828371691e-13 BR00117012 NSC-632839 final compound M16 U2OS 48 152 Hole +0.32253655869892034 6.444946188035399e-13 BR00117013 delanzomib final compound L11 U2OS 48 270 Hole +0.2792718749524375 6.454065304263431e-13 BR00117012 GK921 final compound H24 U2OS 48 362 Hole 0.6318117919457538 1.3103144160526817e-130 BR00117011 PF-431396 final compound L20 U2OS 48 696 Interphase 0.6109499255874085 8.011022484874414e-128 BR00117013 PF-431396 final compound L20 U2OS 48 728 Interphase 0.6083883574704131 2.7705557472835556e-123 BR00117012 PF-431396 final compound L20 U2OS 48 712 Interphase @@ -529,6 +5209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5440198159943382 3.536118414369033e-86 BR00117010 danusertib final compound E05 U2OS 48 628 Interphase 0.3004999288593368 3.1905767941167637e-85 BR00117012 L-Cystine final compound O08 U2OS 48 2124 Interphase 0.5885826771653543 6.213318764613518e-82 BR00117010 AMG900 final compound N09 U2OS 48 508 Interphase +0.5835110220440882 3.971743583227677e-79 BR00117012 danusertib final compound E05 U2OS 48 500 Interphase +0.5602007438275753 1.8880402033435763e-75 BR00117011 danusertib final compound E05 U2OS 48 516 Interphase +0.5607117222620982 6.202141517218026e-75 BR00117012 epothilone-b final compound F07 U2OS 48 514 Interphase +0.5640971239981141 7.750464261875726e-75 BR00117010 epothilone-b final compound F07 U2OS 48 504 Interphase +0.3351708726657265 9.620936526718258e-72 BR00117010 PP-2 final compound J10 U2OS 48 1434 Interphase +0.5971853131366818 7.02408309605621e-71 BR00117011 epothilone-b final compound F07 U2OS 48 426 Interphase +0.519529993178981 2.0063093437756294e-69 BR00117010 danusertib final compound N18 U2OS 48 556 Interphase +0.5701013513513513 1.1869093235812271e-67 BR00117013 epothilone-b final compound F07 U2OS 48 444 Interphase +0.5414023858015712 9.39706281694868e-67 BR00117010 KG-5 final compound C13 U2OS 48 490 Interphase +0.3288791804039602 1.653132991754454e-62 BR00117013 PP-2 final compound J10 U2OS 48 1292 Interphase +0.2850029700781277 1.976454487741365e-62 BR00117011 PP-2 final compound J10 U2OS 48 1734 Interphase +0.3814990006662225 3.750009926196247e-62 BR00117012 polydatin final compound K08 U2OS 48 950 Interphase +0.5237220691766147 2.6143423993166404e-61 BR00117012 danusertib final compound N18 U2OS 48 484 Interphase +0.5471249943978846 1.3776499899059538e-58 BR00117011 ixabepilone final compound J21 U2OS 48 424 Interphase +0.3314974182444062 6.513721902591567e-57 BR00117010 polydatin final compound K08 U2OS 48 1160 Interphase +0.48776650699727625 3.511628417064375e-55 BR00117013 danusertib final compound E05 U2OS 48 504 Interphase +0.46956666481717807 3.039995399277979e-54 BR00117011 danusertib final compound N18 U2OS 48 536 Interphase +0.3496458985053876 1.63309737594001e-52 BR00117013 polydatin final compound K08 U2OS 48 960 Interphase +0.29395221870030114 8.576306200989012e-52 BR00117012 PP-2 final compound J10 U2OS 48 1348 Interphase +0.24203725402670834 3.747525537585116e-48 BR00117010 SB-203580 final compound L08 U2OS 48 1854 Interphase +0.4584623323013416 4.664285277881048e-44 BR00117013 danusertib final compound N18 U2OS 48 456 Interphase +0.35340314136125656 9.578293678517748e-43 BR00117010 BMS-536924 final compound B15 U2OS 48 764 Interphase +0.5010928298221116 7.345169285237985e-42 BR00117013 ganetespib final compound M10 U2OS 48 364 Interphase +0.2714826930818187 3.1937327702075306e-41 BR00117011 polydatin final compound K08 U2OS 48 1254 Interphase +0.5375858250276855 1.4918293247614745e-40 BR00117010 ixabepilone final compound J21 U2OS 48 300 Interphase +0.5119047619047619 1.7938101713990327e-40 BR00117012 ixabepilone final compound J21 U2OS 48 336 Interphase +0.21961234945975805 3.86051551097766e-40 BR00117012 PETCM final compound I04 U2OS 48 1874 Interphase +0.21353620146904512 1.882595044562342e-38 BR00117011 SB-203580 final compound L08 U2OS 48 1906 Interphase +0.462780134899913 1.6083255740604024e-37 BR00117012 KG-5 final compound C13 U2OS 48 384 Interphase +0.4881656804733728 6.8721038843979565e-37 BR00117013 ixabepilone final compound J21 U2OS 48 338 Interphase +0.48455208818506446 7.985256367103386e-37 BR00117012 azeliragon final compound C08 U2OS 48 342 Interphase +0.3304492621130991 2.393311929406316e-36 BR00117011 BMS-536924 final compound B15 U2OS 48 744 Interphase +0.20815677966101695 3.32508202776298e-36 BR00117013 SB-203580 final compound L08 U2OS 48 1888 Interphase +0.23557238436290462 3.604983516877627e-36 BR00117012 AC-710 final compound I03 U2OS 48 1462 Interphase +0.4494792762465811 3.914822633187953e-36 BR00117013 KG-5 final compound C13 U2OS 48 388 Interphase +0.5076854928017719 4.906341900573446e-36 BR00117011 ganetespib final compound I17 U2OS 48 300 Interphase +0.4505208333333333 1.7851837621873088e-35 BR00117011 KG-5 final compound C13 U2OS 48 384 Interphase +0.47126436781609193 2.642167214895131e-35 BR00117012 ganetespib final compound M10 U2OS 48 348 Interphase +0.3343814029418134 8.639171075089793e-35 BR00117013 BMS-536924 final compound B15 U2OS 48 694 Interphase +0.270108959170044 5.625712264923726e-34 BR00117013 FK-866 final compound D08 U2OS 48 1046 Interphase +0.2264784946236559 7.522313637098716e-34 BR00117012 SB-203580 final compound L08 U2OS 48 1488 Interphase +0.44137507673419274 2.85109361141144e-32 BR00117012 NVP-HSP990 final compound E23 U2OS 48 360 Interphase +0.43520793317550366 1.0015552544997004e-31 BR00117010 ganetespib final compound M10 U2OS 48 366 Interphase +0.4769736842105263 1.1571793683184909e-31 BR00117010 colchicine final compound K17 U2OS 48 304 Interphase +0.44946436888681884 1.546802087016353e-31 BR00117012 ganetespib final compound I17 U2OS 48 342 Interphase +0.4404867766689721 5.747515085564912e-31 BR00117011 ganetespib final compound M10 U2OS 48 348 Interphase +0.45325596389426176 6.142010463550282e-31 BR00117012 briciclib final compound H01 U2OS 48 330 Interphase +0.5683207293069512 4.390349071257602e-30 BR00117012 delanzomib final compound L11 U2OS 48 196 Interphase +0.488612493090105 9.494923462796481e-30 BR00117013 AZD7762 final compound K11 U2OS 48 268 Interphase +0.45921398862575336 1.0522557963127302e-29 BR00117010 PP-121 final compound B16 U2OS 48 308 Interphase +0.4316103346604254 1.1159248275044404e-29 BR00117010 geldanamycin final compound L01 U2OS 48 346 Interphase +0.43019238641015145 1.8139919027256452e-29 BR00117013 7-hydroxystaurosporine final compound L04 U2OS 48 350 Interphase +0.47585075850758507 1.9791565181842987e-28 BR00117013 delanzomib final compound L11 U2OS 48 270 Interphase +0.24316854149567904 2.1685292667194075e-28 BR00117012 PP-1 final compound A22 U2OS 48 1078 Interphase +0.5428762733751016 3.060464410483906e-28 BR00117012 AZD7762 final compound K11 U2OS 48 206 Interphase +0.47058823529411764 1.3570641131758685e-27 BR00117010 oxibendazole final compound M19 U2OS 48 272 Interphase +0.207416819560306 1.5117183037195037e-27 BR00117013 lonafarnib final compound J06 U2OS 48 1434 Interphase +0.5494260204081632 1.8531790421783696e-27 BR00117011 AZD7762 final compound I05 U2OS 48 196 Interphase +0.4135910385910386 2.4077489632222867e-27 BR00117012 7-hydroxystaurosporine final compound L04 U2OS 48 352 Interphase +0.4124293785310734 2.475188927670621e-27 BR00117011 GK921 final compound H24 U2OS 48 354 Interphase +0.415732275314818 4.797489831689882e-27 BR00117011 geldanamycin final compound L01 U2OS 48 340 Interphase +0.20489012689569794 6.893668905968169e-27 BR00117010 PP-1 final compound A22 U2OS 48 1440 Interphase +0.40154939652679483 8.28211895778851e-27 BR00117012 GK921 final compound H24 U2OS 48 362 Interphase +0.5129032258064516 9.268973672812205e-27 BR00117012 BVT-948 final compound B12 U2OS 48 220 Interphase +0.49715791454921887 1.1554057253279367e-26 BR00117010 UNC2025 final compound N06 U2OS 48 230 Interphase +0.30634920634920637 1.6867782225850898e-26 BR00117012 KU-60019 final compound I07 U2OS 48 630 Interphase +0.47711609233857477 6.183350004092809e-26 BR00117012 homoharringtonine final compound N15 U2OS 48 244 Interphase +0.528380249192432 1.2323659545111746e-25 BR00117011 AZD7762 final compound K11 U2OS 48 198 Interphase +0.4232547387887194 1.7040680127429995e-25 BR00117011 UNC2025 final compound N06 U2OS 48 308 Interphase +0.21262542129934528 3.3383591251431203e-25 BR00117013 lonafarnib final compound F22 U2OS 48 1244 Interphase +0.4715447154471545 4.270604679231667e-25 BR00117010 AZD7762 final compound K11 U2OS 48 246 Interphase +0.5659712018806935 4.724634130464155e-25 BR00117013 puromycin final compound C22 U2OS 48 164 Interphase +0.4245847176079734 5.105331217190955e-25 BR00117010 GK921 final compound H24 U2OS 48 300 Interphase +0.640625 5.107376513336746e-25 BR00117012 puromycin final compound C22 U2OS 48 128 Interphase +0.4556664709336465 6.878333712619028e-25 BR00117012 UNC2025 final compound N06 U2OS 48 262 Interphase +0.4471155170039928 8.982005731131507e-25 BR00117010 CYT-997 final compound E06 U2OS 48 270 Interphase +0.4498226698822528 1.3168633685393322e-24 BR00117012 colchicine final compound K17 U2OS 48 266 Interphase +0.37322523235119637 1.4014098638157447e-24 BR00117010 azeliragon final compound C08 U2OS 48 390 Interphase +0.39112276612276614 1.8091702866489087e-24 BR00117013 RGB-286638 final compound K21 U2OS 48 352 Interphase +0.26705916483216435 1.937278624834963e-24 BR00117012 BMS-536924 final compound B15 U2OS 48 766 Interphase +0.19426858894225707 2.2458296847770465e-24 BR00117013 PP-1 final compound A22 U2OS 48 1444 Interphase +0.46751978799818683 3.0229321383066722e-24 BR00117012 CYT-997 final compound E06 U2OS 48 238 Interphase +0.41938171047760087 8.563077689529849e-24 BR00117013 colchicine final compound K17 U2OS 48 296 Interphase +0.5780461427541457 1.2269187327169246e-23 BR00117012 NSC-632839 final compound M16 U2OS 48 152 Interphase +0.4161073825503356 1.728758904669022e-23 BR00117012 NSC-95397 final compound D03 U2OS 48 298 Interphase +0.6479338842975206 2.2664156317947448e-23 BR00117012 AZD7762 final compound I05 U2OS 48 110 Interphase +0.4206002331002331 3.032608737112042e-23 BR00117012 geldanamycin final compound L01 U2OS 48 288 Interphase +0.4126249537208441 5.043346159790783e-23 BR00117013 oxibendazole final compound M19 U2OS 48 296 Interphase +0.34348891672566856 6.60872534856528e-23 BR00117011 RGB-286638 final compound K21 U2OS 48 430 Interphase +0.6076388888888888 1.1679814470946576e-22 BR00117012 CYT-997 final compound C09 U2OS 48 126 Interphase 0.5129679266075802 1.498964282695512e-255 BR00117012 L-Cystine final compound O08 U2OS 48 2124 Large 0.5654304963512511 2.7467622825829237e-216 BR00117012 AC-710 final compound I03 U2OS 48 1462 Large 0.47477781081894005 1.2209105436019833e-191 BR00117012 PETCM final compound I04 U2OS 48 1874 Large @@ -539,6 +5309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.6044809734888792 4.727628729741479e-95 BR00117012 fludarabine-phosphate final compound N12 U2OS 48 554 Large 0.38324049947009 2.1215581207655275e-93 BR00117012 quinine final compound A05 U2OS 48 1418 Large 0.5909090909090909 5.384046493815067e-93 BR00117011 fludarabine-phosphate final compound N12 U2OS 48 572 Large +0.6178232230392157 1.1989374028414364e-91 BR00117013 fludarabine-phosphate final compound N12 U2OS 48 510 Large +0.5029881431272708 2.248223499943444e-90 BR00117013 KU-60019 final compound I07 U2OS 48 778 Large +0.6052736957425107 3.703781759685309e-88 BR00117010 fludarabine-phosphate final compound N12 U2OS 48 514 Large +0.7954671088999448 3.545368380424346e-85 BR00117013 AZD7762 final compound K11 U2OS 48 268 Large +0.4345864661654135 2.3539576761693583e-79 BR00117011 deferasirox final compound L14 U2OS 48 930 Large +0.858003730451002 7.374960299992545e-78 BR00117012 AZD7762 final compound K11 U2OS 48 206 Large +0.2976554536187564 4.689786497599799e-77 BR00117011 AC-710 final compound I03 U2OS 48 1962 Large +0.5699962430731661 2.4061601654994417e-76 BR00117013 danusertib final compound E05 U2OS 48 504 Large +0.5809951365506921 3.1709608711278635e-76 BR00117012 danusertib final compound N18 U2OS 48 484 Large +0.44910500902306977 5.021826400938065e-74 BR00117011 KU-60019 final compound I07 U2OS 48 812 Large +0.7764227642276422 1.7015051242216362e-73 BR00117010 AZD7762 final compound K11 U2OS 48 246 Large +0.41311347990228736 3.886011827868883e-73 BR00117012 amlodipine final compound A03 U2OS 48 950 Large +0.5033464765948842 4.9954210672887855e-73 BR00117010 danusertib final compound E05 U2OS 48 628 Large +0.4166666666666667 2.7343252307884626e-71 BR00117012 deferasirox final compound L14 U2OS 48 912 Large +0.5511811023622047 2.919632451477664e-71 BR00117010 AMG900 final compound N09 U2OS 48 508 Large +0.5770840499942668 4.708317144541654e-71 BR00117013 danusertib final compound N18 U2OS 48 456 Large +0.7907936507936508 8.150128843754997e-71 BR00117010 delanzomib final compound L11 U2OS 48 224 Large +0.5571428571428572 2.487947259749517e-70 BR00117012 AMG900 final compound N09 U2OS 48 490 Large +0.8914193358801058 2.5890724443647535e-70 BR00117013 puromycin final compound C22 U2OS 48 164 Large +0.8503774879890186 5.820019956908662e-70 BR00117011 delanzomib final compound L11 U2OS 48 186 Large +0.6564198105884179 6.910382912441264e-70 BR00117012 azeliragon final compound C08 U2OS 48 342 Large +0.423848075293278 9.39263420734582e-69 BR00117013 deferasirox final compound L14 U2OS 48 846 Large +0.7897779639715123 1.5460444758497736e-68 BR00117012 BVT-948 final compound B12 U2OS 48 220 Large +0.4097727763279242 1.9988338711711893e-68 BR00117010 deferasirox final compound L14 U2OS 48 904 Large +0.8227964928472543 5.285338106381034e-68 BR00117011 AZD7762 final compound K11 U2OS 48 198 Large +0.8218688490624676 2.0811014029401554e-67 BR00117012 delanzomib final compound L11 U2OS 48 196 Large +0.49013737616988673 2.4457141931030533e-66 BR00117013 AMG900 final compound N09 U2OS 48 604 Large +0.3735680240057819 1.2338241047026455e-65 BR00117013 FK-866 final compound D08 U2OS 48 1046 Large +0.7472519679455357 4.044291450748226e-65 BR00117013 BVT-948 final compound B12 U2OS 48 236 Large +0.5969415331883198 4.308943894259755e-65 BR00117010 azeliragon final compound C08 U2OS 48 390 Large +0.8096301020408163 1.6460293890091033e-64 BR00117011 AZD7762 final compound I05 U2OS 48 196 Large +0.5119639736523727 1.9861690158489495e-62 BR00117011 danusertib final compound E05 U2OS 48 516 Large +0.5021777728458081 4.285562229491893e-62 BR00117011 danusertib final compound N18 U2OS 48 536 Large +0.4945464924262502 1.062562174302898e-60 BR00117011 AMG900 final compound N09 U2OS 48 542 Large +0.5089516129032258 2.3517099452281825e-59 BR00117011 GSK1070916 final compound C04 U2OS 48 500 Large +0.8204761904761905 4.697243792371003e-59 BR00117013 AZD7762 final compound I05 U2OS 48 168 Large +0.4005999122079696 1.207698609732809e-58 BR00117011 JTE-607 final compound C14 U2OS 48 812 Large +0.8230596805827963 1.7313750676343696e-58 BR00117013 NSC-663284 final compound G06 U2OS 48 166 Large +0.7895044413277232 3.479086304400409e-58 BR00117013 NSC-632839 final compound M16 U2OS 48 184 Large +0.5919540229885057 6.373782082426027e-57 BR00117012 ganetespib final compound M10 U2OS 48 348 Large +0.5678024734065554 5.673412747392395e-56 BR00117011 azeliragon final compound C08 U2OS 48 372 Large +0.5709428692854107 2.1884117980030877e-55 BR00117013 ganetespib final compound M10 U2OS 48 364 Large +0.3707075571071719 3.36289956172695e-55 BR00117010 FK-866 final compound L09 U2OS 48 892 Large +0.28392039471756775 1.038755079267652e-54 BR00117013 fludarabine final compound B06 U2OS 48 1524 Large +0.3614733720068042 3.6169864010856854e-53 BR00117010 JTE-607 final compound C14 U2OS 48 908 Large +0.5258899676375405 5.923838511775375e-53 BR00117013 GSK1070916 final compound C04 U2OS 48 414 Large +0.5652558329922227 2.5160018780435505e-52 BR00117013 7-hydroxystaurosporine final compound L04 U2OS 48 350 Large +0.6072646733111849 4.6526362565113656e-52 BR00117011 ganetespib final compound I17 U2OS 48 300 Large +0.5524337040842155 8.279611551609196e-52 BR00117010 ganetespib final compound M10 U2OS 48 366 Large +0.5531863080833448 9.91960557729323e-52 BR00117012 GK921 final compound H24 U2OS 48 362 Large +0.8240807498197549 1.505995764708309e-51 BR00117012 NSC-632839 final compound M16 U2OS 48 152 Large +0.34775705085498554 1.8312674993003857e-51 BR00117010 FK-866 final compound D08 U2OS 48 950 Large +0.8682170542635659 1.8712867804926783e-51 BR00117010 AZD7762 final compound I05 U2OS 48 128 Large +0.8200371057513914 1.9686415967055054e-51 BR00117010 NSC-663284 final compound G06 U2OS 48 154 Large +0.5682076936346386 3.962128032368204e-51 BR00117011 geldanamycin final compound L01 U2OS 48 340 Large +0.29253809966759686 5.0613882192267084e-51 BR00117012 fludarabine final compound B06 U2OS 48 1342 Large +0.8861016949152543 8.9145925013382e-51 BR00117011 ryuvidine final compound A14 U2OS 48 118 Large +0.44639065134296857 1.2409570462432975e-50 BR00117010 danusertib final compound N18 U2OS 48 556 Large +0.7220512820512821 1.9633468138642526e-50 BR00117013 thiostrepton final compound B02 U2OS 48 200 Large +0.5506831131831131 8.220005472298255e-50 BR00117012 7-hydroxystaurosporine final compound L04 U2OS 48 352 Large +0.8781016949152542 1.1562976652729477e-49 BR00117011 NSC-663284 final compound G06 U2OS 48 118 Large +0.5882352941176471 2.007799401581255e-49 BR00117011 7-hydroxystaurosporine final compound L04 U2OS 48 306 Large +0.8391570798838834 2.0668930908238695e-49 BR00117013 ryuvidine final compound A14 U2OS 48 142 Large +0.5906976744186047 3.3668334583232825e-49 BR00117010 GK921 final compound H24 U2OS 48 300 Large +0.8968472604836241 4.296830386819797e-49 BR00117012 ponatinib final compound C20 U2OS 48 108 Large +0.8706349206349207 5.436033633561094e-49 BR00117013 ponatinib final compound C20 U2OS 48 120 Large +0.3779332842260339 4.694844224795054e-47 BR00117013 PF-431396 final compound L20 U2OS 48 728 Large +0.2558859975216852 8.028374084432212e-47 BR00117010 AC-710 final compound I03 U2OS 48 1614 Large +0.8776859504132232 9.8858892491731e-47 BR00117012 AZD7762 final compound I05 U2OS 48 110 Large +0.5424105987683072 1.0625095648301324e-46 BR00117012 ganetespib final compound I17 U2OS 48 342 Large +0.3933933933933934 2.2008957622443085e-46 BR00117013 JTE-607 final compound C14 U2OS 48 666 Large +0.8257918552036199 2.9258663815278383e-46 BR00117011 NSC-632839 final compound M16 U2OS 48 136 Large +0.5556484356341056 8.033356355181472e-46 BR00117013 azeliragon final compound C08 U2OS 48 316 Large +0.8347086771692923 1.9303373357876835e-45 BR00117010 ponatinib final compound C20 U2OS 48 124 Large +0.715811037308337 8.269616202019252e-45 BR00117012 thiostrepton final compound B02 U2OS 48 178 Large +0.7174873327270365 2.907869326827578e-44 BR00117013 UNC1999 final compound H19 U2OS 48 172 Large +0.3694549064720992 9.77038512606374e-44 BR00117012 PF-431396 final compound L20 U2OS 48 712 Large +0.503744628606507 4.230863843974583e-42 BR00117012 NVP-HSP990 final compound E23 U2OS 48 360 Large +0.6016260162601627 9.393834757367578e-42 BR00117010 NSC-95397 final compound D03 U2OS 48 246 Large +0.3331092485885571 2.2579259759228328e-41 BR00117012 NVP-ADW742 final compound D16 U2OS 48 830 Large +0.6524064171122995 5.063613104037517e-41 BR00117012 UNC1999 final compound H19 U2OS 48 204 Large +0.5352405443051538 1.0794619158358187e-40 BR00117010 ganetespib final compound I17 U2OS 48 306 Large +0.3543954739673999 3.916545806802193e-40 BR00117012 JTE-607 final compound C14 U2OS 48 710 Large +0.23124805014322583 8.478916715363999e-40 BR00117013 AC-710 final compound I03 U2OS 48 1680 Large +0.2760494803949911 5.964128313730455e-39 BR00117011 fludarabine final compound B06 U2OS 48 1148 Large +0.5230263157894737 2.483814113335511e-38 BR00117010 colchicine final compound K17 U2OS 48 304 Large +0.3278789150955398 2.9745555928798894e-38 BR00117010 NVP-ADW742 final compound D16 U2OS 48 794 Large +0.3140963108679835 3.9125234327303556e-38 BR00117013 FK-866 final compound L09 U2OS 48 860 Large +0.7251617814998097 1.5478653958104786e-37 BR00117011 BVT-948 final compound B12 U2OS 48 148 Large +0.320179499524709 5.922441661577479e-37 BR00117012 FK-866 final compound D08 U2OS 48 804 Large 0.636734693877551 1.2116657035967606e-93 BR00117012 AMG900 final compound N09 U2OS 48 490 Metaphase 0.6259842519685039 1.5057868036489477e-93 BR00117010 AMG900 final compound N09 U2OS 48 508 Metaphase 0.5616496086694762 1.5779638828356158e-88 BR00117013 AMG900 final compound N09 U2OS 48 604 Metaphase @@ -549,6 +5409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.4130462560695119 3.670987227805144e-56 BR00117013 PF-431396 final compound L20 U2OS 48 728 Metaphase 0.49714314865830017 3.252648103161243e-55 BR00117012 danusertib final compound N18 U2OS 48 484 Metaphase 0.48276982358052206 9.765508504984101e-55 BR00117012 epothilone-b final compound F07 U2OS 48 514 Metaphase +0.44921248276952974 9.811230771546246e-55 BR00117010 PF-431396 final compound L20 U2OS 48 596 Metaphase +0.4650315639668105 1.8496308644113727e-54 BR00117012 fludarabine-phosphate final compound N12 U2OS 48 554 Metaphase +0.5203959606696784 2.667224618385437e-53 BR00117011 epothilone-b final compound F07 U2OS 48 426 Metaphase +0.47966129032258065 2.457554478592092e-52 BR00117011 GSK1070916 final compound C04 U2OS 48 500 Metaphase +0.46686382578303537 1.2595129538907276e-51 BR00117011 danusertib final compound E05 U2OS 48 516 Metaphase +0.45444709537812794 1.3247199234665631e-50 BR00117011 danusertib final compound N18 U2OS 48 536 Metaphase +0.4577008802085301 4.452022000934329e-49 BR00117010 fludarabine-phosphate final compound N12 U2OS 48 514 Metaphase +0.45660749506903353 3.540506479633155e-48 BR00117013 danusertib final compound E05 U2OS 48 504 Metaphase +0.4106763724598119 4.1610235896087337e-48 BR00117010 danusertib final compound E05 U2OS 48 628 Metaphase +0.44464875058934467 2.5318160359706558e-45 BR00117010 epothilone-b final compound F07 U2OS 48 504 Metaphase +0.4166162597649966 8.275677563775909e-44 BR00117010 danusertib final compound N18 U2OS 48 556 Metaphase +0.43276654411764703 1.098813719988511e-43 BR00117013 fludarabine-phosphate final compound N12 U2OS 48 510 Metaphase +0.441256910096014 2.37629064040224e-43 BR00117010 KG-5 final compound C13 U2OS 48 490 Metaphase +0.4323758743263387 4.712655581247561e-39 BR00117013 danusertib final compound N18 U2OS 48 456 Metaphase +0.42698278635778636 4.481327057476804e-37 BR00117013 epothilone-b final compound F07 U2OS 48 444 Metaphase +0.43427230046948356 1.8452817783792454e-36 BR00117010 GSK1070916 final compound C04 U2OS 48 426 Metaphase +0.4421643820713664 1.8480286784199645e-34 BR00117012 KG-5 final compound C13 U2OS 48 384 Metaphase +0.42006901806121993 6.322699865705708e-34 BR00117011 ixabepilone final compound J21 U2OS 48 424 Metaphase +0.4401041666666667 8.181783151860869e-34 BR00117011 KG-5 final compound C13 U2OS 48 384 Metaphase +0.418554476806904 7.435374287639414e-33 BR00117013 GSK1070916 final compound C04 U2OS 48 414 Metaphase +0.5 2.872475783160653e-31 BR00117010 oxibendazole final compound M19 U2OS 48 272 Metaphase +0.17810794115385736 5.7680013315869075e-30 BR00117012 L-Cystine final compound O08 U2OS 48 2124 Metaphase +0.464031007751938 1.2693830599237507e-29 BR00117010 ixabepilone final compound J21 U2OS 48 300 Metaphase +0.23737958534367704 5.15870991194713e-29 BR00117011 AZ191 final compound I18 U2OS 48 1154 Metaphase +0.21078392673877003 2.2883579779190782e-28 BR00117012 RKI-1447 final compound J04 U2OS 48 1434 Metaphase +0.4226190476190476 2.7773578243816344e-27 BR00117012 ixabepilone final compound J21 U2OS 48 336 Metaphase +0.20250502592318273 1.4252713438678474e-26 BR00117010 NVS-PAK1-1 final compound N14 U2OS 48 1456 Metaphase +0.2143113488786062 1.501693194967906e-26 BR00117013 PP-2 final compound J10 U2OS 48 1292 Metaphase +0.36638159054840413 5.426469667550768e-26 BR00117012 GSK1070916 final compound C04 U2OS 48 424 Metaphase +0.38002314327792974 1.0653711487757436e-25 BR00117013 KG-5 final compound C13 U2OS 48 388 Metaphase +0.1883796038249746 3.192093726156092e-25 BR00117011 NVS-PAK1-1 final compound N14 U2OS 48 1590 Metaphase +0.20220605218064597 1.126348168338784e-24 BR00117012 PP-2 final compound J10 U2OS 48 1348 Metaphase +0.2807807807807808 1.6080198084569434e-23 BR00117013 JTE-607 final compound C14 U2OS 48 666 Metaphase +0.20083233532230368 1.6334454824300382e-23 BR00117012 NVS-PAK1-1 final compound N14 U2OS 48 1306 Metaphase +0.3211302605210421 3.3224102118171056e-23 BR00117012 danusertib final compound E05 U2OS 48 500 Metaphase +0.1822971998163814 3.845461024322435e-23 BR00117013 NVS-PAK1-1 final compound N14 U2OS 48 1560 Metaphase +0.1725535479780827 5.003925295120945e-23 BR00117011 PP-2 final compound J10 U2OS 48 1734 Metaphase +0.1885823403516046 1.0180478432346226e-22 BR00117010 PP-2 final compound J10 U2OS 48 1434 Metaphase +0.1615341359113779 7.649402229872404e-22 BR00117012 PETCM final compound I04 U2OS 48 1874 Metaphase +0.17789235406099413 8.387210040065326e-22 BR00117012 simvastatin final compound N24 U2OS 48 1538 Metaphase +0.3668639053254438 1.2791889553711978e-20 BR00117013 ixabepilone final compound J21 U2OS 48 338 Metaphase +0.16786762025047727 2.288511866473929e-20 BR00117010 RKI-1447 final compound J04 U2OS 48 1612 Metaphase +0.39124877828734683 6.854378764842778e-20 BR00117010 CYT-997 final compound C09 U2OS 48 282 Metaphase +0.22619866258764923 1.0526044725837445e-19 BR00117010 AZ191 final compound I18 U2OS 48 860 Metaphase +0.3756693550149717 1.087182555680325e-19 BR00117010 briciclib final compound H01 U2OS 48 302 Metaphase +0.3809700111069974 1.507371108775787e-19 BR00117013 colchicine final compound K17 U2OS 48 296 Metaphase +0.38969260954872464 2.3228784574896465e-19 BR00117012 oxibendazole final compound M19 U2OS 48 278 Metaphase +0.21710526315789475 3.1121875597639965e-19 BR00117012 deferasirox final compound L14 U2OS 48 912 Metaphase +0.20718475073313783 3.782765955583215e-19 BR00117012 AZ191 final compound I18 U2OS 48 990 Metaphase +0.17350071318718974 4.527013784536816e-19 BR00117012 quinine final compound A05 U2OS 48 1418 Metaphase +0.3540204476374689 5.338762313970918e-19 BR00117012 briciclib final compound H01 U2OS 48 330 Metaphase +0.3933607603915449 9.060336993205212e-19 BR00117012 colchicine final compound K17 U2OS 48 266 Metaphase +0.38766349993115795 1.5404015215815135e-18 BR00117010 CYT-997 final compound E06 U2OS 48 270 Metaphase +0.19559834748363691 1.739292878474413e-18 BR00117012 PP-1 final compound A22 U2OS 48 1078 Metaphase +0.17864398908689846 2.14773845339848e-18 BR00117013 RKI-1447 final compound J04 U2OS 48 1288 Metaphase +0.1872295310925224 3.1040846922774587e-18 BR00117011 PP-1 final compound A22 U2OS 48 1156 Metaphase +0.21594336302352654 4.00243364873255e-18 BR00117011 aminopurvalanol-a final compound K03 U2OS 48 860 Metaphase +0.16715413184772515 4.907528246441851e-18 BR00117010 PP-1 final compound A22 U2OS 48 1440 Metaphase +0.16540808560903528 5.9666657664121635e-18 BR00117012 AC-710 final compound I03 U2OS 48 1462 Metaphase +0.37533755781930966 7.836184317186424e-18 BR00117011 CYT-997 final compound C09 U2OS 48 274 Metaphase +0.20187805439705242 8.89691860647644e-18 BR00117013 AZ191 final compound I18 U2OS 48 968 Metaphase +0.36319881525360975 9.7570530394998e-18 BR00117013 oxibendazole final compound M19 U2OS 48 296 Metaphase +0.16538946755824926 9.860884649596399e-18 BR00117013 PP-1 final compound A22 U2OS 48 1444 Metaphase +0.4028604118993135 2.8787228172085316e-17 BR00117011 oxibendazole final compound M19 U2OS 48 230 Metaphase +0.3594896331738437 4.5938702613186194e-17 BR00117011 BI-2536 final compound I14 U2OS 48 286 Metaphase +0.34539473684210525 1.7747075151443174e-16 BR00117010 colchicine final compound K17 U2OS 48 304 Metaphase +0.19586719964468133 2.2566177264444677e-16 BR00117012 amlodipine final compound A03 U2OS 48 950 Metaphase +0.3274519979242346 3.25682138425556e-16 BR00117011 briciclib final compound H01 U2OS 48 328 Metaphase +0.346454163577959 8.833418878679662e-16 BR00117013 briciclib final compound H01 U2OS 48 284 Metaphase +0.35584263065179095 3.857171285275412e-15 BR00117012 UNC2025 final compound N06 U2OS 48 262 Metaphase +0.13051608647664908 9.936447807966184e-15 BR00117012 dexamethasone final compound O02 U2OS 48 1916 Metaphase +0.18737165494381114 1.0273046174998998e-14 BR00117011 deferasirox final compound L14 U2OS 48 930 Metaphase +0.19581883670101252 1.1777987163014858e-14 BR00117013 deferasirox final compound L14 U2OS 48 846 Metaphase +0.21722689075630253 1.2945838844671332e-14 BR00117011 SKLB1002 final compound P17 U2OS 48 680 Metaphase +0.30083805359568055 1.884307201679981e-14 BR00117013 BI-2536 final compound I14 U2OS 48 348 Metaphase +0.3559747550472471 5.752770978294688e-14 BR00117012 CYT-997 final compound E06 U2OS 48 238 Metaphase +0.3127180263102593 8.284257309694053e-14 BR00117011 UNC2025 final compound N06 U2OS 48 308 Metaphase +0.37383177570093457 1.0582776613609869e-13 BR00117013 buparlisib final compound L12 U2OS 48 214 Metaphase +0.30932549403886983 1.089813882134732e-13 BR00117011 BI-2536 final compound E21 U2OS 48 312 Metaphase +0.1372670807453416 1.2265995185845163e-13 BR00117012 trihexyphenidyl final compound E02 U2OS 48 1610 Metaphase +0.346969696969697 2.2116566062904541e-13 BR00117013 CYT-997 final compound C09 U2OS 48 240 Metaphase +0.20751798451436365 2.4924678741764356e-13 BR00117012 SKLB1002 final compound P17 U2OS 48 678 Metaphase +0.3534706331045004 3.4044154737056e-13 BR00117011 colchicine final compound K17 U2OS 48 230 Metaphase +0.29995981514968856 3.744054602864869e-13 BR00117010 BI-2536 final compound E21 U2OS 48 316 Metaphase +0.18816758523142954 4.914665865594674e-13 BR00117011 JTE-607 final compound C14 U2OS 48 812 Metaphase +0.2705152215220155 8.645396057497221e-13 BR00117012 BI-2536 final compound E21 U2OS 48 382 Metaphase +0.39133403687379725 9.1899633365738e-13 BR00117012 thiostrepton final compound B02 U2OS 48 178 Metaphase +0.3597985347985348 1.1942396771164537e-12 BR00117012 buparlisib final compound D11 U2OS 48 210 Metaphase +0.11948717948717949 1.5283911822013512e-12 BR00117011 desonide final compound E16 U2OS 48 1950 Metaphase +0.12257614995683808 3.119194094305276e-12 BR00117012 M-25 final compound C07 U2OS 48 1800 Metaphase 0.6806870548806032 4.699205155393756e-49 BR00117012 BVT-948 final compound B12 U2OS 48 220 MetaphaseAlignment 0.6935897435897436 4.249619314552399e-46 BR00117013 thiostrepton final compound B02 U2OS 48 200 MetaphaseAlignment 0.7043888509528835 3.652626009216287e-43 BR00117012 thiostrepton final compound B02 U2OS 48 178 MetaphaseAlignment @@ -559,6 +5509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.6722009991184249 8.694015949075415e-36 BR00117013 puromycin final compound C22 U2OS 48 164 MetaphaseAlignment 0.3816705073476635 7.940842440566154e-34 BR00117010 fludarabine-phosphate final compound N12 U2OS 48 514 MetaphaseAlignment 0.6094143216655228 7.979216358587873e-33 BR00117011 delanzomib final compound L11 U2OS 48 186 MetaphaseAlignment +0.3551419562478375 1.1401022716285435e-31 BR00117012 fludarabine-phosphate final compound N12 U2OS 48 554 MetaphaseAlignment +0.655534941249227 3.7108234549536944e-31 BR00117010 NSC-663284 final compound G06 U2OS 48 154 MetaphaseAlignment +0.7341597796143251 1.864140926477399e-30 BR00117012 ponatinib final compound C20 U2OS 48 108 MetaphaseAlignment +0.3409090909090909 7.415915788643604e-30 BR00117011 fludarabine-phosphate final compound N12 U2OS 48 572 MetaphaseAlignment +0.5574950792499741 7.303934952731634e-29 BR00117012 delanzomib final compound L11 U2OS 48 196 MetaphaseAlignment +0.5811764705882353 1.822813669356199e-27 BR00117011 thiostrepton final compound B02 U2OS 48 170 MetaphaseAlignment +0.31306989217886266 1.2143736434801548e-26 BR00117013 AMG900 final compound N09 U2OS 48 604 MetaphaseAlignment +0.483739837398374 1.9007785863475516e-26 BR00117010 AZD7762 final compound K11 U2OS 48 246 MetaphaseAlignment +0.6615593220338983 1.1334877242603561e-25 BR00117011 NSC-663284 final compound G06 U2OS 48 118 MetaphaseAlignment +0.5451145395044413 1.1642592421511983e-25 BR00117013 NSC-632839 final compound M16 U2OS 48 184 MetaphaseAlignment +0.33877551020408164 2.5950097260878497e-25 BR00117012 AMG900 final compound N09 U2OS 48 490 MetaphaseAlignment +0.65 5.067941540748431e-25 BR00117013 ponatinib final compound C20 U2OS 48 120 MetaphaseAlignment +0.640625 5.107376513336746e-25 BR00117012 puromycin final compound C22 U2OS 48 128 MetaphaseAlignment +0.5079152518054426 1.1184458361757016e-24 BR00117012 AZD7762 final compound K11 U2OS 48 206 MetaphaseAlignment +0.4417910447761194 4.647917957304435e-24 BR00117013 AZD7762 final compound K11 U2OS 48 268 MetaphaseAlignment +0.3188976377952756 3.100172184132004e-23 BR00117010 AMG900 final compound N09 U2OS 48 508 MetaphaseAlignment +0.5304761904761904 1.1933083722552577e-22 BR00117013 AZD7762 final compound I05 U2OS 48 168 MetaphaseAlignment +0.5897215353187829 1.3874779353745602e-22 BR00117013 ryuvidine final compound A14 U2OS 48 142 MetaphaseAlignment +0.38452611218568666 2.190702299021777e-22 BR00117012 briciclib final compound H01 U2OS 48 330 MetaphaseAlignment +0.5285093863827403 3.3890094724329545e-22 BR00117013 NSC-663284 final compound G06 U2OS 48 166 MetaphaseAlignment +0.1842027548982629 9.505205773468458e-22 BR00117012 RKI-1447 final compound J04 U2OS 48 1434 MetaphaseAlignment +0.22697368421052633 5.35675431707068e-21 BR00117012 deferasirox final compound L14 U2OS 48 912 MetaphaseAlignment +0.45794392523364486 1.3055173031923767e-20 BR00117013 buparlisib final compound L12 U2OS 48 214 MetaphaseAlignment +0.475765306122449 1.6535825156435018e-20 BR00117011 AZD7762 final compound I05 U2OS 48 196 MetaphaseAlignment +0.3694306471940099 2.2145198917696868e-20 BR00117011 briciclib final compound H01 U2OS 48 328 MetaphaseAlignment +0.6066115702479339 2.5703224104513877e-20 BR00117012 AZD7762 final compound I05 U2OS 48 110 MetaphaseAlignment +0.15424973767051417 3.4072233445007715e-20 BR00117011 SB-203580 final compound L08 U2OS 48 1906 MetaphaseAlignment +0.3868937430581266 4.017166392444117e-20 BR00117013 colchicine final compound K17 U2OS 48 296 MetaphaseAlignment +0.48628168278024564 2.477522808041213e-19 BR00117012 buparlisib final compound L12 U2OS 48 172 MetaphaseAlignment +0.5697627118644067 9.625260530729588e-19 BR00117011 ryuvidine final compound A14 U2OS 48 118 MetaphaseAlignment +0.5269607843137255 2.5993780878876423e-18 BR00117010 thiostrepton final compound B02 U2OS 48 144 MetaphaseAlignment +0.36122221493672546 5.254011033780646e-18 BR00117010 briciclib final compound H01 U2OS 48 302 MetaphaseAlignment +0.7155448717948718 6.5916991966763124e-18 BR00117011 puromycin final compound C22 U2OS 48 78 MetaphaseAlignment +0.40103305785123966 7.857640744718524e-18 BR00117013 CYT-997 final compound C09 U2OS 48 240 MetaphaseAlignment +0.5282805429864253 1.4764749654005786e-17 BR00117011 NSC-632839 final compound M16 U2OS 48 136 MetaphaseAlignment +0.1643021000310474 2.162568053945141e-17 BR00117010 PP-2 final compound J10 U2OS 48 1434 MetaphaseAlignment +0.36967952910398955 2.6537803159943743e-17 BR00117012 oxibendazole final compound M19 U2OS 48 278 MetaphaseAlignment +0.20157998683344305 4.298235599199752e-17 BR00117011 deferasirox final compound L14 U2OS 48 930 MetaphaseAlignment +0.49405191059841386 4.5889139893016914e-17 BR00117012 NSC-632839 final compound M16 U2OS 48 152 MetaphaseAlignment +0.5422394234618978 4.655610491738408e-17 BR00117010 BVT-948 final compound B12 U2OS 48 118 MetaphaseAlignment +0.47149573905377606 4.8069186446822376e-17 BR00117013 romidepsin final compound N19 U2OS 48 164 MetaphaseAlignment +0.5257994186046512 5.696413252035384e-17 BR00117010 AZD7762 final compound I05 U2OS 48 128 MetaphaseAlignment +0.15282929178095467 7.265896675680038e-17 BR00117010 RKI-1447 final compound J04 U2OS 48 1612 MetaphaseAlignment +0.4931480776551199 1.4172217557114887e-16 BR00117011 BVT-948 final compound B12 U2OS 48 148 MetaphaseAlignment +0.36057859415523646 1.7858101693569119e-16 BR00117011 CYT-997 final compound C09 U2OS 48 274 MetaphaseAlignment +0.23093380042962403 2.7020724418132425e-16 BR00117012 SKLB1002 final compound P17 U2OS 48 678 MetaphaseAlignment +0.41808952468850946 3.759070005602483e-16 BR00117011 AZD7762 final compound K11 U2OS 48 198 MetaphaseAlignment +0.7439903846153846 5.193890433334457e-16 BR00117010 SU3327 final compound I20 U2OS 48 52 MetaphaseAlignment +0.2547824373271357 6.142173301579886e-16 BR00117011 AMG900 final compound N09 U2OS 48 542 MetaphaseAlignment +0.6275757575757576 1.6831280703654246e-15 BR00117010 puromycin final compound C22 U2OS 48 88 MetaphaseAlignment +0.38161708619374524 1.8474196352539178e-15 BR00117011 colchicine final compound K17 U2OS 48 230 MetaphaseAlignment +0.15136962317270744 4.165511132151057e-15 BR00117012 AC-710 final compound I03 U2OS 48 1462 MetaphaseAlignment +0.5884387351778656 5.72520529564568e-15 BR00117013 LDN-212854 final compound K01 U2OS 48 92 MetaphaseAlignment +0.2140093369203988 8.330107514515278e-15 BR00117012 JTE-607 final compound C14 U2OS 48 710 MetaphaseAlignment +0.3256578947368421 1.1614742921767238e-14 BR00117010 colchicine final compound K17 U2OS 48 304 MetaphaseAlignment +0.13675944498163348 1.3397536676517717e-14 BR00117011 PP-2 final compound J10 U2OS 48 1734 MetaphaseAlignment +0.375 2.058032828220321e-14 BR00117013 CYT-997 final compound E06 U2OS 48 224 MetaphaseAlignment +0.6784274193548387 2.861980919695249e-14 BR00117012 ryuvidine final compound A14 U2OS 48 62 MetaphaseAlignment +0.38104138851802405 3.163442608982547e-14 BR00117010 buparlisib final compound D11 U2OS 48 214 MetaphaseAlignment +0.32802075611564124 5.3655092624619745e-14 BR00117013 briciclib final compound H01 U2OS 48 284 MetaphaseAlignment +0.4032258064516129 6.672334771684455e-14 BR00117013 buparlisib final compound D11 U2OS 48 186 MetaphaseAlignment +0.3196038504257682 8.518676305984776e-14 BR00117013 oxibendazole final compound M19 U2OS 48 296 MetaphaseAlignment +0.13433095096287473 1.0090132089972726e-13 BR00117013 AC-710 final compound I03 U2OS 48 1680 MetaphaseAlignment +0.6144189383070301 1.024208594221532e-13 BR00117010 ryuvidine final compound A14 U2OS 48 82 MetaphaseAlignment +0.32111397374555267 1.1816266195346567e-13 BR00117011 BI-2536 final compound I14 U2OS 48 286 MetaphaseAlignment +0.3304865938430983 1.8485072699568385e-13 BR00117012 colchicine final compound K17 U2OS 48 266 MetaphaseAlignment +0.34704836291363017 2.6101936652634997e-13 BR00117012 CYT-997 final compound E06 U2OS 48 238 MetaphaseAlignment +0.12552774987910575 3.5324132198130606e-13 BR00117010 SB-203580 final compound L08 U2OS 48 1854 MetaphaseAlignment +0.3235294117647059 5.433900876338521e-13 BR00117010 oxibendazole final compound M19 U2OS 48 272 MetaphaseAlignment +0.3608058608058608 1.1272242626207439e-12 BR00117012 buparlisib final compound D11 U2OS 48 210 MetaphaseAlignment +0.64375 1.3817106946033626e-12 BR00117011 SU3327 final compound I20 U2OS 48 60 MetaphaseAlignment +0.2332816755893679 1.3824194036952411e-12 BR00117013 danusertib final compound E05 U2OS 48 504 MetaphaseAlignment +0.18047192113832017 1.6592034180465259e-12 BR00117013 deferasirox final compound L14 U2OS 48 846 MetaphaseAlignment +0.173361829575028 2.0931310527908127e-12 BR00117010 JTE-607 final compound C14 U2OS 48 908 MetaphaseAlignment +0.3902325581395349 2.136425912696934e-12 BR00117010 buparlisib final compound L12 U2OS 48 172 MetaphaseAlignment +0.15301180816340593 2.6735557630651652e-12 BR00117011 AZ191 final compound I18 U2OS 48 1154 MetaphaseAlignment +0.1317201622777512 3.1811789936488756e-12 BR00117011 RKI-1447 final compound J04 U2OS 48 1558 MetaphaseAlignment +0.3525641025641026 6.872753723998857e-12 BR00117011 buparlisib final compound D11 U2OS 48 208 MetaphaseAlignment +0.1981981981981982 7.448390036230676e-12 BR00117013 JTE-607 final compound C14 U2OS 48 666 MetaphaseAlignment +0.20317460317460317 8.644653142887791e-12 BR00117012 KU-60019 final compound I07 U2OS 48 630 MetaphaseAlignment +0.18455497382198952 8.753593095161083e-12 BR00117010 BMS-536924 final compound B15 U2OS 48 764 MetaphaseAlignment +0.1730270460513848 9.055640995485956e-12 BR00117010 AZ191 final compound I18 U2OS 48 860 MetaphaseAlignment +0.29067552602436325 1.2361226813531898e-11 BR00117010 GK921 final compound H24 U2OS 48 300 MetaphaseAlignment +0.2632299894981964 1.7329753659161463e-11 BR00117012 GK921 final compound H24 U2OS 48 362 MetaphaseAlignment +0.257391779491227 4.212039226879476e-11 BR00117013 ganetespib final compound M10 U2OS 48 364 MetaphaseAlignment +0.26436781609195403 4.23928195607748e-11 BR00117012 ganetespib final compound M10 U2OS 48 348 MetaphaseAlignment +0.58125 5.232819600832431e-11 BR00117012 NSC-663284 final compound G06 U2OS 48 70 MetaphaseAlignment +0.37915742793791574 5.6754100281247734e-11 BR00117011 buparlisib final compound L12 U2OS 48 164 MetaphaseAlignment +0.42810702675668916 6.065768272402641e-11 BR00117010 ponatinib final compound C20 U2OS 48 124 MetaphaseAlignment +0.2285504047093451 8.060987407868203e-11 BR00117013 SKLB1002 final compound P17 U2OS 48 450 MetaphaseAlignment 0.451988447816777 1.9447193922691088e-196 BR00117012 L-Cystine final compound O08 U2OS 48 2124 OutOfFocus 0.35167496896942085 1.4952675554067933e-103 BR00117012 PETCM final compound I04 U2OS 48 1874 OutOfFocus 0.4742682656007106 2.695991890067651e-97 BR00117012 polydatin final compound K08 U2OS 48 950 OutOfFocus @@ -569,6 +5609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.3411085316979084 2.089075596299232e-48 BR00117011 deferasirox final compound L14 U2OS 48 930 OutOfFocus 0.5473270196139316 2.887936004846017e-47 BR00117012 azeliragon final compound C08 U2OS 48 342 OutOfFocus 0.3132406890684037 8.23003909188765e-46 BR00117013 FK-866 final compound D08 U2OS 48 1046 OutOfFocus +0.3267543859649123 1.7801050160985148e-43 BR00117012 deferasirox final compound L14 U2OS 48 912 OutOfFocus +0.4113499716022222 1.3280351861103346e-42 BR00117012 fludarabine-phosphate final compound N12 U2OS 48 554 OutOfFocus +0.31512769264934487 3.14219738751873e-42 BR00117012 amlodipine final compound A03 U2OS 48 950 OutOfFocus +0.3372064244252238 8.849670658377654e-40 BR00117013 KU-60019 final compound I07 U2OS 48 778 OutOfFocus +0.30903792947824893 1.1438456180409876e-38 BR00117010 deferasirox final compound L14 U2OS 48 904 OutOfFocus +0.5176965669988925 1.5462218289093975e-37 BR00117011 ganetespib final compound I17 U2OS 48 300 OutOfFocus +0.47097929694614776 7.103465341017862e-37 BR00117013 ganetespib final compound M10 U2OS 48 364 OutOfFocus +0.3067013470716803 1.2453988990063228e-35 BR00117013 deferasirox final compound L14 U2OS 48 846 OutOfFocus +0.3894752748290582 3.0737693189271854e-35 BR00117010 fludarabine-phosphate final compound N12 U2OS 48 514 OutOfFocus +0.2607306071576948 3.7402124782592484e-35 BR00117010 polydatin final compound K08 U2OS 48 1160 OutOfFocus +0.3408408408408408 1.10465848020606e-34 BR00117013 JTE-607 final compound C14 U2OS 48 666 OutOfFocus +0.36713286713286714 1.130634316268143e-34 BR00117011 fludarabine-phosphate final compound N12 U2OS 48 572 OutOfFocus +0.4495084897229669 2.65085463485034e-34 BR00117011 azeliragon final compound C08 U2OS 48 372 OutOfFocus +0.3001572940545286 9.28445518471262e-33 BR00117011 JTE-607 final compound C14 U2OS 48 812 OutOfFocus +0.4540229885057471 1.063925595176051e-32 BR00117012 ganetespib final compound M10 U2OS 48 348 OutOfFocus +0.31637917391992404 6.424861547800636e-32 BR00117012 JTE-607 final compound C14 U2OS 48 710 OutOfFocus +0.4949695964621338 1.144315842648882e-30 BR00117013 AZD7762 final compound K11 U2OS 48 268 OutOfFocus +0.42683998153690383 2.2696742520758748e-30 BR00117010 ganetespib final compound M10 U2OS 48 366 OutOfFocus +0.4339387464387464 2.3119295425126005e-30 BR00117012 7-hydroxystaurosporine final compound L04 U2OS 48 352 OutOfFocus +0.46405228758169936 4.0569273339183365e-30 BR00117011 7-hydroxystaurosporine final compound L04 U2OS 48 306 OutOfFocus +0.2922043114917141 4.2255717222606144e-30 BR00117010 KU-60019 final compound I07 U2OS 48 786 OutOfFocus +0.23161028478835777 4.9472424814571466e-30 BR00117011 polydatin final compound K08 U2OS 48 1254 OutOfFocus +0.426365868631062 6.893486800109623e-30 BR00117012 NVP-HSP990 final compound E23 U2OS 48 360 OutOfFocus +0.2058342510206579 8.226811421814364e-29 BR00117013 fludarabine final compound B06 U2OS 48 1524 OutOfFocus +0.3905304629238779 9.682936668773236e-29 BR00117013 GSK1070916 final compound C04 U2OS 48 414 OutOfFocus +0.22697348881054766 1.5125028118624974e-28 BR00117013 lonafarnib final compound F22 U2OS 48 1244 OutOfFocus +0.2802211871433449 1.6506175251066298e-28 BR00117011 KU-60019 final compound I07 U2OS 48 812 OutOfFocus +0.20027038886187637 1.9781268141889395e-28 BR00117011 lonafarnib final compound J06 U2OS 48 1590 OutOfFocus +0.4751674183408501 2.749778153669801e-28 BR00117013 delanzomib final compound L11 U2OS 48 270 OutOfFocus +0.5539660565041276 2.901380428560498e-28 BR00117011 AZD7762 final compound K11 U2OS 48 198 OutOfFocus +0.20964104720276489 4.292789080793068e-28 BR00117010 PP-2 final compound J10 U2OS 48 1434 OutOfFocus +0.26135851470609617 1.0445724990039292e-27 BR00117010 JTE-607 final compound C14 U2OS 48 908 OutOfFocus +0.18052416954952943 7.572113565621147e-27 BR00117010 SB-203580 final compound L08 U2OS 48 1854 OutOfFocus +0.41521476625840953 1.0314295380117979e-26 BR00117011 geldanamycin final compound L01 U2OS 48 340 OutOfFocus +0.3860918858348164 2.579125443529674e-26 BR00117010 azeliragon final compound C08 U2OS 48 390 OutOfFocus +0.5322697606961566 2.773165710929735e-26 BR00117012 delanzomib final compound L11 U2OS 48 196 OutOfFocus +0.40207941056078594 7.385991160962525e-26 BR00117013 7-hydroxystaurosporine final compound L04 U2OS 48 350 OutOfFocus +0.21171063398107962 7.984856541332157e-26 BR00117013 PP-2 final compound J10 U2OS 48 1292 OutOfFocus +0.1753177966101695 9.438402368245233e-26 BR00117013 SB-203580 final compound L08 U2OS 48 1888 OutOfFocus +0.1824313885315028 9.813779139435504e-26 BR00117011 PP-2 final compound J10 U2OS 48 1734 OutOfFocus +0.24349148418491484 1.4826081227338944e-25 BR00117013 polydatin final compound K08 U2OS 48 960 OutOfFocus +0.24980688395983186 5.054070869876262e-25 BR00117010 FK-866 final compound L09 U2OS 48 892 OutOfFocus +0.2683246073298429 1.3581869219616283e-24 BR00117010 BMS-536924 final compound B15 U2OS 48 764 OutOfFocus +0.20233693520083662 1.8593246324138702e-24 BR00117012 fludarabine final compound B06 U2OS 48 1342 OutOfFocus +0.19510876044207826 2.2065462594249056e-24 BR00117013 lonafarnib final compound J06 U2OS 48 1434 OutOfFocus +0.3294298314048501 2.3592040990218028e-24 BR00117012 AVL-292 final compound A24 U2OS 48 494 OutOfFocus +0.3832131212330797 1.849266285662093e-23 BR00117011 ganetespib final compound M10 U2OS 48 348 OutOfFocus +0.32043548387096776 3.978425105049652e-23 BR00117011 GSK1070916 final compound C04 U2OS 48 500 OutOfFocus +0.20664799743298037 2.3007335402135157e-22 BR00117010 lonafarnib final compound F22 U2OS 48 1172 OutOfFocus +0.19093272739670886 6.035746584633686e-22 BR00117012 PP-2 final compound J10 U2OS 48 1348 OutOfFocus +0.4805586111243962 7.294462000115054e-22 BR00117012 AZD7762 final compound K11 U2OS 48 206 OutOfFocus +0.22656895403064622 7.458961772221362e-22 BR00117010 FK-866 final compound D08 U2OS 48 950 OutOfFocus +0.15739769150052466 5.174489087529781e-21 BR00117011 SB-203580 final compound L08 U2OS 48 1906 OutOfFocus +0.3871912401324166 5.620328942175151e-21 BR00117010 PP-121 final compound B16 U2OS 48 308 OutOfFocus +0.3789109147360879 6.558600682744554e-21 BR00117013 azeliragon final compound C08 U2OS 48 316 OutOfFocus +0.36598871810795425 7.11936511068479e-21 BR00117012 ganetespib final compound I17 U2OS 48 342 OutOfFocus +0.47619047619047616 1.5723684111631268e-20 BR00117011 AZD7762 final compound I05 U2OS 48 196 OutOfFocus +0.46495676955030674 1.909792110104872e-20 BR00117011 homoharringtonine final compound N15 U2OS 48 206 OutOfFocus +0.509256538348516 4.6133806621840223e-20 BR00117013 puromycin final compound C22 U2OS 48 164 OutOfFocus +0.33943191311612364 7.475260223607238e-20 BR00117010 AVL-292 final compound A24 U2OS 48 380 OutOfFocus +0.49176470588235294 1.5224651955657708e-19 BR00117011 UNC1999 final compound H19 U2OS 48 170 OutOfFocus +0.19612418173569252 3.872322922773833e-19 BR00117011 lonafarnib final compound F22 U2OS 48 1112 OutOfFocus +0.1638709677419355 1.4073952257268177e-18 BR00117010 lonafarnib final compound J06 U2OS 48 1550 OutOfFocus +0.14662168594084532 2.267200747985514e-18 BR00117012 trazodone final compound G08 U2OS 48 1906 OutOfFocus +0.38339202862094024 3.565277852625594e-18 BR00117010 homoharringtonine final compound N15 U2OS 48 268 OutOfFocus +0.3360263863670437 9.082549542918722e-18 BR00117010 geldanamycin final compound L01 U2OS 48 346 OutOfFocus +0.46136363636363636 1.088048306690847e-17 BR00117011 anisomycin final compound N03 U2OS 48 176 OutOfFocus +0.21726616611373029 1.1070867673462375e-17 BR00117012 NVP-ADW742 final compound D16 U2OS 48 830 OutOfFocus +0.35906040268456374 1.8501287761722436e-17 BR00117012 NSC-95397 final compound D03 U2OS 48 298 OutOfFocus +0.3384348203625312 1.8831471081751487e-17 BR00117011 AVL-292 final compound A24 U2OS 48 332 OutOfFocus +0.5395098774693673 2.0722296781140414e-17 BR00117010 ponatinib final compound C20 U2OS 48 124 OutOfFocus +0.3944926161766698 2.437884850912629e-17 BR00117013 homoharringtonine final compound N15 U2OS 48 242 OutOfFocus +0.4444063143445436 2.889202912201294e-17 BR00117011 delanzomib final compound L11 U2OS 48 186 OutOfFocus +0.5270106589147286 4.607068781627956e-17 BR00117010 AZD7762 final compound I05 U2OS 48 128 OutOfFocus +0.3756605989430417 5.700156948130257e-17 BR00117011 NVP-HSP990 final compound E23 U2OS 48 262 OutOfFocus +0.1473613259431125 7.825170801755306e-17 BR00117012 A205804 final compound M06 U2OS 48 1728 OutOfFocus +0.5537190082644629 8.421197609597536e-17 BR00117012 AZD7762 final compound I05 U2OS 48 110 OutOfFocus +0.6120567375886525 9.03256702811597e-17 BR00117010 LDN-212854 final compound K01 U2OS 48 94 OutOfFocus +0.40569752827817346 1.086667070024632e-16 BR00117012 BVT-948 final compound B12 U2OS 48 220 OutOfFocus +0.4600028019052956 1.138321267855555e-16 BR00117013 NSC-663284 final compound G06 U2OS 48 166 OutOfFocus +0.22962457620110807 1.206621982274617e-16 BR00117011 PF-431396 final compound L20 U2OS 48 696 OutOfFocus +0.5373559322033898 1.2370231955548565e-16 BR00117011 ryuvidine final compound A14 U2OS 48 118 OutOfFocus +0.1788354153036228 1.6792165170305403e-16 BR00117011 fludarabine final compound B06 U2OS 48 1148 OutOfFocus +0.35266122766122765 1.7760948753620776e-16 BR00117010 7-hydroxystaurosporine final compound L04 U2OS 48 286 OutOfFocus +0.3821138211382114 2.1491616189074596e-16 BR00117010 NSC-95397 final compound D03 U2OS 48 246 OutOfFocus +0.2883968986689374 4.776056387663449e-16 BR00117011 ixabepilone final compound J21 U2OS 48 424 OutOfFocus +0.28792876360729924 7.775326407153201e-16 BR00117011 BVT-948 final compound O16 U2OS 48 422 OutOfFocus +0.37398373983739835 1.0513214845737789e-15 BR00117010 AZD7762 final compound K11 U2OS 48 246 OutOfFocus +0.3088739963739964 2.0086429975278106e-15 BR00117013 PP-121 final compound B16 U2OS 48 352 OutOfFocus +0.5958498023715415 2.183241225096653e-15 BR00117013 LDN-212854 final compound K01 U2OS 48 92 OutOfFocus 0.42540325611461044 1.1787535454459283e-59 BR00117013 PF-431396 final compound L20 U2OS 48 728 Polylobed 0.7018253968253968 5.0813519285991284e-54 BR00117010 delanzomib final compound L11 U2OS 48 224 Polylobed 0.4374053736469844 7.84270821265129e-52 BR00117010 PF-431396 final compound L20 U2OS 48 596 Polylobed @@ -579,6 +5709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.26824278488429243 6.315284588147462e-46 BR00117010 PP-2 final compound J10 U2OS 48 1434 Polylobed 0.6879487179487179 2.351088779774083e-45 BR00117013 thiostrepton final compound B02 U2OS 48 200 Polylobed 0.229800629590766 1.60993535188206e-44 BR00117011 SB-203580 final compound L08 U2OS 48 1906 Polylobed +0.43554308617234466 2.7127572728394375e-43 BR00117012 danusertib final compound E05 U2OS 48 500 Polylobed +0.563782971163045 3.603974086827419e-40 BR00117013 delanzomib final compound L11 U2OS 48 270 Polylobed +0.2325268817204301 1.1229395493968045e-35 BR00117012 SB-203580 final compound L08 U2OS 48 1488 Polylobed +0.24515865078643512 1.349471769443978e-34 BR00117013 PP-2 final compound J10 U2OS 48 1292 Polylobed +0.3180628272251309 1.4712968707528036e-34 BR00117010 BMS-536924 final compound B15 U2OS 48 764 Polylobed +0.540650406504065 2.593777687838178e-33 BR00117010 AZD7762 final compound K11 U2OS 48 246 Polylobed +0.5481526132898376 2.798361504150929e-33 BR00117013 BVT-948 final compound B12 U2OS 48 236 Polylobed +0.6434028798119307 5.244016823178294e-33 BR00117013 puromycin final compound C22 U2OS 48 164 Polylobed +0.19777601086188298 3.6184844680573763e-32 BR00117010 SB-203580 final compound L08 U2OS 48 1854 Polylobed +0.36959142108982085 2.8890277043761822e-30 BR00117010 KG-5 final compound C13 U2OS 48 490 Polylobed +0.5784145504461222 9.766155193444817e-30 BR00117011 delanzomib final compound L11 U2OS 48 186 Polylobed +0.29736406773758217 1.53756228916945e-29 BR00117011 BMS-536924 final compound B15 U2OS 48 744 Polylobed +0.577689490347011 1.8813341433805135e-28 BR00117012 thiostrepton final compound B02 U2OS 48 178 Polylobed +0.5473945923547083 7.941239419557176e-28 BR00117012 delanzomib final compound L11 U2OS 48 196 Polylobed +0.562529219261337 1.1793812202819956e-27 BR00117013 NSC-632839 final compound M16 U2OS 48 184 Polylobed +0.2973088904066232 1.4579619714740372e-27 BR00117013 BMS-536924 final compound B15 U2OS 48 694 Polylobed +0.18114406779661016 1.79503166335329e-27 BR00117013 SB-203580 final compound L08 U2OS 48 1888 Polylobed +0.39531657963446476 1.8334464577783124e-27 BR00117012 KG-5 final compound C13 U2OS 48 384 Polylobed +0.3426466699406898 3.095919917424531e-27 BR00117012 epothilone-b final compound F07 U2OS 48 514 Polylobed +0.46826976229961303 3.892796219637009e-27 BR00117013 AZD7762 final compound K11 U2OS 48 268 Polylobed +0.3093721565059145 4.28150782831092e-27 BR00117010 danusertib final compound E05 U2OS 48 628 Polylobed +0.19437449137667123 4.595589987190138e-27 BR00117010 RKI-1447 final compound J04 U2OS 48 1612 Polylobed +0.50670297444491 3.069010653491141e-26 BR00117012 BVT-948 final compound B12 U2OS 48 220 Polylobed +0.18671403046030802 3.8531903517799545e-26 BR00117013 AC-710 final compound I03 U2OS 48 1680 Polylobed +0.22250749911027506 1.5943643030277147e-25 BR00117011 PP-1 final compound A22 U2OS 48 1156 Polylobed +0.3338048090523338 2.5514059514839337e-25 BR00117010 epothilone-b final compound F07 U2OS 48 504 Polylobed +0.5918367346938775 4.992727513903755e-25 BR00117010 NSC-663284 final compound G06 U2OS 48 154 Polylobed +0.30324558042800065 5.55776577192434e-25 BR00117013 AMG900 final compound N09 U2OS 48 604 Polylobed +0.3197858292182212 9.385982338539665e-25 BR00117011 danusertib final compound N18 U2OS 48 536 Polylobed +0.2258416039616252 1.2497878337269872e-24 BR00117012 PP-1 final compound A22 U2OS 48 1078 Polylobed +0.3558774027814687 1.557617406915242e-24 BR00117011 epothilone-b final compound F07 U2OS 48 426 Polylobed +0.31204256793949153 8.591949884270351e-24 BR00117011 AMG900 final compound N09 U2OS 48 542 Polylobed +0.6531986531986532 1.4154868365505538e-23 BR00117012 ponatinib final compound C20 U2OS 48 108 Polylobed +0.2607382378538883 1.768680810933274e-23 BR00117012 BMS-536924 final compound B15 U2OS 48 766 Polylobed +0.3150737106241878 3.18078168495176e-23 BR00117011 danusertib final compound E05 U2OS 48 516 Polylobed +0.18124666004095644 8.052245980071942e-23 BR00117011 RKI-1447 final compound J04 U2OS 48 1558 Polylobed +0.5849673202614379 9.950476271608107e-23 BR00117010 thiostrepton final compound B02 U2OS 48 144 Polylobed +0.2993912562257886 1.3380922757541261e-22 BR00117010 danusertib final compound N18 U2OS 48 556 Polylobed +0.6150793650793651 2.8819661943666615e-22 BR00117013 ponatinib final compound C20 U2OS 48 120 Polylobed +0.6055593220338983 2.6390064029207502e-21 BR00117011 NSC-663284 final compound G06 U2OS 48 118 Polylobed +0.18198313215722686 2.8374863553480443e-21 BR00117010 PP-1 final compound A22 U2OS 48 1440 Polylobed +0.1797525206854675 9.504898744856509e-21 BR00117013 lonafarnib final compound J06 U2OS 48 1434 Polylobed +0.19870318713276752 1.6425045992334145e-20 BR00117010 polydatin final compound K08 U2OS 48 1160 Polylobed +0.4634367975512937 1.7098789712313593e-20 BR00117012 AZD7762 final compound K11 U2OS 48 206 Polylobed +0.21543491484184915 4.659620459340969e-20 BR00117013 polydatin final compound K08 U2OS 48 960 Polylobed +0.7036363636363636 8.519850839819711e-20 BR00117010 puromycin final compound C22 U2OS 48 88 Polylobed +0.1654275092936803 1.0868617019030451e-19 BR00117010 AC-710 final compound I03 U2OS 48 1614 Polylobed +0.2933070866141732 1.1447936909186371e-19 BR00117010 AMG900 final compound N09 U2OS 48 508 Polylobed +0.15503415431249448 1.8330931574707222e-19 BR00117010 sotrastaurin final compound K12 U2OS 48 1814 Polylobed +0.5486506827222879 1.9495082429666662e-19 BR00117013 ryuvidine final compound A14 U2OS 48 142 Polylobed +0.5641957364341085 2.2573125368079656e-19 BR00117010 AZD7762 final compound I05 U2OS 48 128 Polylobed +0.1724773961601709 3.123572404803336e-19 BR00117013 PP-1 final compound A22 U2OS 48 1444 Polylobed +0.2938775510204082 4.654447997175857e-19 BR00117012 AMG900 final compound N09 U2OS 48 490 Polylobed +0.3145539906103286 5.052731106375525e-19 BR00117010 GSK1070916 final compound C04 U2OS 48 426 Polylobed +0.49068366489212667 5.245746640408026e-19 BR00117013 NSC-663284 final compound G06 U2OS 48 166 Polylobed +0.4857142857142857 7.025344558874657e-19 BR00117013 AZD7762 final compound I05 U2OS 48 168 Polylobed +0.1708756202322161 8.950628558162128e-19 BR00117012 RKI-1447 final compound J04 U2OS 48 1434 Polylobed +0.3087198025039676 1.8516119325021656e-18 BR00117012 GSK1070916 final compound C04 U2OS 48 424 Polylobed +0.7111378205128205 1.138226746457645e-17 BR00117011 puromycin final compound C22 U2OS 48 78 Polylobed +0.46285714285714286 2.8225422582276186e-17 BR00117011 thiostrepton final compound B02 U2OS 48 170 Polylobed +0.6822094691535151 4.83772215188477e-17 BR00117010 ryuvidine final compound A14 U2OS 48 82 Polylobed +0.5570247933884298 5.2234227246148385e-17 BR00117012 AZD7762 final compound I05 U2OS 48 110 Polylobed +0.3125 5.771342396991125e-17 BR00117011 KG-5 final compound C13 U2OS 48 384 Polylobed +0.13863404689092762 7.512793170412721e-17 BR00117011 AC-710 final compound I03 U2OS 48 1962 Polylobed +0.28405572755417957 8.491822656261193e-17 BR00117013 danusertib final compound N18 U2OS 48 456 Polylobed +0.24126984126984127 1.6940372548115764e-16 BR00117012 KU-60019 final compound I07 U2OS 48 630 Polylobed +0.15059210421034103 3.876659595097418e-16 BR00117011 MCOPPB final compound B17 U2OS 48 1582 Polylobed +0.26308790752143857 4.3015881243202365e-16 BR00117010 fludarabine-phosphate final compound N12 U2OS 48 514 Polylobed +0.48553483060525315 4.555595933170229e-16 BR00117011 BVT-948 final compound B12 U2OS 48 148 Polylobed +0.5177544386096524 5.145513952609015e-16 BR00117010 ponatinib final compound C20 U2OS 48 124 Polylobed +0.4177818797108137 5.345433664552507e-16 BR00117011 AZD7762 final compound K11 U2OS 48 198 Polylobed +0.2625152625152625 7.188104852292395e-16 BR00117013 danusertib final compound E05 U2OS 48 504 Polylobed +0.47656813266041814 7.333568865682023e-16 BR00117012 NSC-632839 final compound M16 U2OS 48 152 Polylobed +0.33732004429678847 1.3812419752750777e-15 BR00117010 GK921 final compound H24 U2OS 48 300 Polylobed +0.5208135593220339 1.3825590492014137e-15 BR00117011 ryuvidine final compound A14 U2OS 48 118 Polylobed +0.2820870322967159 1.432964349152933e-15 BR00117011 RGB-286638 final compound K21 U2OS 48 430 Polylobed +0.1408037128856185 1.557478094936834e-15 BR00117010 ingenol-mebutate final compound M11 U2OS 48 1744 Polylobed +0.33503813957554696 1.7585849368173992e-15 BR00117010 briciclib final compound H01 U2OS 48 302 Polylobed +0.49615384615384617 2.039526912357101e-15 BR00117011 NSC-632839 final compound M16 U2OS 48 136 Polylobed +0.2579120710784314 2.1506891822872667e-15 BR00117013 fludarabine-phosphate final compound N12 U2OS 48 510 Polylobed +0.2633404754616876 2.9516286614507373e-15 BR00117012 danusertib final compound N18 U2OS 48 484 Polylobed +0.16226466206149262 3.020287235514189e-15 BR00117013 RKI-1447 final compound J04 U2OS 48 1288 Polylobed +0.5090084078473242 5.10474064540352e-15 BR00117010 BVT-948 final compound B12 U2OS 48 118 Polylobed +0.3878504672897196 9.599747788861153e-15 BR00117013 buparlisib final compound L12 U2OS 48 214 Polylobed +0.1607405822135938 1.2658641281053393e-14 BR00117011 polydatin final compound K08 U2OS 48 1254 Polylobed +0.3293224731580896 1.2905227028515618e-14 BR00117013 colchicine final compound K17 U2OS 48 296 Polylobed +0.29775317275317276 2.2725348743420645e-14 BR00117013 RGB-286638 final compound K21 U2OS 48 352 Polylobed +0.1485311681306827 2.386629856751629e-14 BR00117012 lonafarnib final compound J06 U2OS 48 1442 Polylobed +0.30654761904761907 2.4354382901312486e-14 BR00117012 ixabepilone final compound J21 U2OS 48 336 Polylobed +0.16905502624927085 2.6051848363454127e-14 BR00117011 lonafarnib final compound F22 U2OS 48 1112 Polylobed 0.45939329832647047 2.0809192164358633e-49 BR00117010 fludarabine-phosphate final compound N12 U2OS 48 514 Prometaphase 0.44558057598039214 3.736009786524595e-46 BR00117013 fludarabine-phosphate final compound N12 U2OS 48 510 Prometaphase 0.40559440559440557 1.872386825567846e-42 BR00117011 fludarabine-phosphate final compound N12 U2OS 48 572 Prometaphase @@ -589,6 +5809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.25207257775775843 1.5101931661155355e-26 BR00117011 deferasirox final compound L14 U2OS 48 930 Prometaphase 0.2529335007750721 6.562835246226899e-26 BR00117010 deferasirox final compound L14 U2OS 48 904 Prometaphase 0.19924843862686759 1.8819836658477021e-25 BR00117010 PP-2 final compound J10 U2OS 48 1434 Prometaphase +0.32112834940504104 3.231614542476761e-25 BR00117011 AMG900 final compound N09 U2OS 48 542 Prometaphase +0.23464912280701755 1.9980010064383395e-22 BR00117012 deferasirox final compound L14 U2OS 48 912 Prometaphase +0.19483828673420073 6.439232492789495e-22 BR00117013 PP-2 final compound J10 U2OS 48 1292 Prometaphase +0.3144236982620821 1.0016592839589607e-21 BR00117012 danusertib final compound N18 U2OS 48 484 Prometaphase +0.17641536775522584 2.42773506953584e-21 BR00117012 simvastatin final compound N24 U2OS 48 1538 Prometaphase +0.29031157900155724 2.8315092286831237e-21 BR00117010 danusertib final compound N18 U2OS 48 556 Prometaphase +0.18794997063436372 2.927651195802495e-21 BR00117012 PP-2 final compound J10 U2OS 48 1348 Prometaphase +0.27122636740471134 7.456174744693645e-21 BR00117010 danusertib final compound E05 U2OS 48 628 Prometaphase +0.25495527291582243 6.352823766594225e-20 BR00117012 SKLB1002 final compound P17 U2OS 48 678 Prometaphase +0.29259415797877336 1.244958484868703e-19 BR00117013 danusertib final compound E05 U2OS 48 504 Prometaphase +0.21931201930765765 1.3490960572525178e-19 BR00117010 JTE-607 final compound C14 U2OS 48 908 Prometaphase +0.4527237074943804 1.7517229861214144e-19 BR00117012 AZD7762 final compound K11 U2OS 48 206 Prometaphase +0.1847649918962723 8.086436133906932e-19 BR00117011 simvastatin final compound N24 U2OS 48 1234 Prometaphase +0.17093005261528937 8.27442127278622e-19 BR00117010 PP-1 final compound A22 U2OS 48 1440 Prometaphase +0.22041014318212232 1.711912636799464e-18 BR00117013 deferasirox final compound L14 U2OS 48 846 Prometaphase +0.3611295681063123 5.600767920427725e-18 BR00117010 GK921 final compound H24 U2OS 48 300 Prometaphase +0.5039653929343908 8.889736714208524e-18 BR00117012 NSC-632839 final compound M16 U2OS 48 152 Prometaphase +0.26809158937133126 6.389315460911129e-17 BR00117011 danusertib final compound E05 U2OS 48 516 Prometaphase +0.22761476275273018 1.1876499353590063e-16 BR00117012 PF-431396 final compound L20 U2OS 48 712 Prometaphase +0.18489078632466843 1.2872753543137017e-16 BR00117012 PP-1 final compound A22 U2OS 48 1078 Prometaphase +0.34539473684210525 1.7747075151443174e-16 BR00117010 colchicine final compound K17 U2OS 48 304 Prometaphase +0.4432304922714011 1.9438751104454763e-16 BR00117012 thiostrepton final compound B02 U2OS 48 178 Prometaphase +0.15816731411642004 2.1423322659418863e-16 BR00117010 NVS-PAK1-1 final compound N14 U2OS 48 1456 Prometaphase +0.2213398776326273 3.7981031657706256e-16 BR00117013 PF-431396 final compound L20 U2OS 48 728 Prometaphase +0.3262411347517731 4.987022003778908e-16 BR00117012 briciclib final compound H01 U2OS 48 330 Prometaphase +0.37398373983739835 1.0513214845737789e-15 BR00117010 AZD7762 final compound K11 U2OS 48 246 Prometaphase +0.4125641025641026 1.3818058065369586e-15 BR00117013 thiostrepton final compound B02 U2OS 48 200 Prometaphase +0.16358024691358025 1.5070136537834131e-15 BR00117010 simvastatin final compound N24 U2OS 48 1296 Prometaphase +0.1408649453532262 1.7146037365612131e-15 BR00117011 PP-2 final compound J10 U2OS 48 1734 Prometaphase +0.33193451795510676 3.4267161082008273e-15 BR00117010 briciclib final compound H01 U2OS 48 302 Prometaphase +0.3102520312580862 4.833027592388185e-15 BR00117012 ganetespib final compound I17 U2OS 48 342 Prometaphase +0.31065417317369426 6.0896360014595804e-15 BR00117013 GK921 final compound H24 U2OS 48 340 Prometaphase +0.23623134005139607 6.551027282924404e-15 BR00117010 SKLB1002 final compound P17 U2OS 48 590 Prometaphase +0.216881667080129 7.311401807992825e-15 BR00117011 PF-431396 final compound L20 U2OS 48 696 Prometaphase +0.13304179221069076 9.436412496398498e-15 BR00117010 SB-203580 final compound L08 U2OS 48 1854 Prometaphase +0.2963791607689147 1.7246242114002146e-14 BR00117012 GK921 final compound H24 U2OS 48 362 Prometaphase +0.14168692606603972 2.3604681203567716e-14 BR00117011 NVS-PAK1-1 final compound N14 U2OS 48 1590 Prometaphase +0.22961155175920275 3.091794023660019e-14 BR00117010 PF-431396 final compound L20 U2OS 48 596 Prometaphase +0.46486928104575165 3.3374736130279886e-14 BR00117010 thiostrepton final compound B02 U2OS 48 144 Prometaphase +0.14675793072686444 4.867672095384155e-14 BR00117013 PP-1 final compound A22 U2OS 48 1444 Prometaphase +0.15389506369445466 5.593182881337532e-14 BR00117012 NVS-PAK1-1 final compound N14 U2OS 48 1306 Prometaphase +0.1629826570925284 7.045051192446866e-14 BR00117011 PP-1 final compound A22 U2OS 48 1156 Prometaphase +0.1932278203189777 1.0249887583843788e-13 BR00117011 JTE-607 final compound C14 U2OS 48 812 Prometaphase +0.29310344827586204 1.3931636084514706e-13 BR00117012 ganetespib final compound M10 U2OS 48 348 Prometaphase +0.33088235294117646 1.4001186874096715e-13 BR00117010 oxibendazole final compound M19 U2OS 48 272 Prometaphase +0.23178716085002496 3.6363931924280564e-13 BR00117011 danusertib final compound N18 U2OS 48 536 Prometaphase +0.2498307579102281 6.407483621125374e-13 BR00117013 SKLB1002 final compound P17 U2OS 48 450 Prometaphase +0.2637437185929648 8.895545589884967e-13 BR00117010 RGB-286638 final compound K21 U2OS 48 400 Prometaphase +0.20277224291778567 9.203520797703641e-13 BR00117011 SKLB1002 final compound P17 U2OS 48 680 Prometaphase +0.45591085271317827 9.520144812700636e-13 BR00117010 AZD7762 final compound I05 U2OS 48 128 Prometaphase +0.4809917355371901 1.279703833447617e-12 BR00117012 AZD7762 final compound I05 U2OS 48 110 Prometaphase +0.13709677419354838 1.320003813691881e-12 BR00117012 SB-203580 final compound L08 U2OS 48 1488 Prometaphase +0.3164179104477612 1.7334327743936183e-12 BR00117013 AZD7762 final compound K11 U2OS 48 268 Prometaphase +0.309425356489487 2.18942711867855e-12 BR00117010 CYT-997 final compound C09 U2OS 48 282 Prometaphase +0.3107457428068115 1.047596655101543e-11 BR00117012 UNC2025 final compound N06 U2OS 48 262 Prometaphase +0.23583877995642702 1.0924705203028224e-11 BR00117013 danusertib final compound N18 U2OS 48 456 Prometaphase +0.13691208487115628 1.781848758740226e-11 BR00117012 fludarabine final compound B06 U2OS 48 1342 Prometaphase +0.29288073038073037 2.132548506614645e-11 BR00117012 geldanamycin final compound L01 U2OS 48 288 Prometaphase +0.114900314795383 2.2465504766905506e-11 BR00117011 SB-203580 final compound L08 U2OS 48 1906 Prometaphase +0.25893995507255174 3.349905177642348e-11 BR00117013 ganetespib final compound M10 U2OS 48 364 Prometaphase +0.26441260744985673 3.4644668630794367e-11 BR00117013 7-hydroxystaurosporine final compound L04 U2OS 48 350 Prometaphase +0.29752920789311865 4.690197918616319e-11 BR00117010 homoharringtonine final compound N15 U2OS 48 268 Prometaphase +0.43507273455224876 5.917076813814734e-11 BR00117010 BVT-948 final compound B12 U2OS 48 118 Prometaphase +0.27699560698596376 6.294759607818206e-11 BR00117010 ganetespib final compound I17 U2OS 48 306 Prometaphase +0.2575595700595701 8.743852223836193e-11 BR00117013 RGB-286638 final compound K21 U2OS 48 352 Prometaphase +0.11025641025641025 9.72116907115696e-11 BR00117011 desonide final compound E16 U2OS 48 1950 Prometaphase +0.23328761404973464 2.66345494520693e-10 BR00117013 PF-03758309 final compound N21 U2OS 48 410 Prometaphase +0.24297417226078052 2.9276980356227683e-10 BR00117012 RGB-286638 final compound K21 U2OS 48 374 Prometaphase +0.2103960396039604 2.9745159018285266e-10 BR00117010 epothilone-b final compound F07 U2OS 48 504 Prometaphase +0.35340998170891036 3.1044692879850105e-10 BR00117012 buparlisib final compound L12 U2OS 48 172 Prometaphase +0.3008130081300813 3.182609689053834e-10 BR00117010 NSC-95397 final compound D03 U2OS 48 246 Prometaphase +0.12462829925528275 3.6449232192055265e-10 BR00117012 RKI-1447 final compound J04 U2OS 48 1434 Prometaphase +0.3139086719731881 4.671134005164073e-10 BR00117012 BVT-948 final compound B12 U2OS 48 220 Prometaphase +0.24591774094536525 4.754901839866536e-10 BR00117012 NVP-HSP990 final compound E23 U2OS 48 360 Prometaphase +0.279912301810112 5.256394596052011e-10 BR00117011 CYT-997 final compound C09 U2OS 48 274 Prometaphase +0.11705580182112052 6.531837996736892e-10 BR00117011 MCOPPB final compound B17 U2OS 48 1582 Prometaphase +0.24616355866355866 7.056205247786564e-10 BR00117013 PP-121 final compound B16 U2OS 48 352 Prometaphase +0.40625 7.851514581889473e-10 BR00117012 puromycin final compound C22 U2OS 48 128 Prometaphase +0.452781112444978 8.058121428350306e-10 BR00117012 pyrrolidine-dithiocarbamate final compound O22 U2OS 48 98 Prometaphase +0.26143790849673204 8.622420471530326e-10 BR00117010 PP-121 final compound B16 U2OS 48 308 Prometaphase +0.11695193127418191 9.103229478821816e-10 BR00117013 NVS-PAK1-1 final compound N14 U2OS 48 1560 Prometaphase +0.1571316931202673 9.482151827816153e-10 BR00117013 FK-866 final compound L09 U2OS 48 860 Prometaphase +0.18412698412698414 9.536727938149933e-10 BR00117012 KU-60019 final compound I07 U2OS 48 630 Prometaphase +0.22215748666696544 1.1679569179739238e-09 BR00117011 ixabepilone final compound J21 U2OS 48 424 Prometaphase +0.2558569419328913 1.1714801228339411e-09 BR00117010 BI-2536 final compound E21 U2OS 48 316 Prometaphase +0.24458506971240418 1.712210948008775e-09 BR00117013 BVT-948 final compound O16 U2OS 48 342 Prometaphase +0.1038135593220339 2.8226200283530303e-09 BR00117013 SB-203580 final compound L08 U2OS 48 1888 Prometaphase +0.24404761904761904 3.4268510925403425e-09 BR00117012 ixabepilone final compound J21 U2OS 48 336 Prometaphase +0.2585153646797482 3.809121735176794e-09 BR00117013 colchicine final compound K17 U2OS 48 296 Prometaphase +0.26974038870761813 4.2649415529098676e-09 BR00117012 colchicine final compound K17 U2OS 48 266 Prometaphase 0.6518768509192586 4.9298163937011624e-147 BR00117013 PF-431396 final compound L20 U2OS 48 728 SmallIrregular 0.6549792740875543 6.880964571125156e-128 BR00117010 danusertib final compound E05 U2OS 48 628 SmallIrregular 0.6000007879351372 8.127580338930628e-120 BR00117012 PF-431396 final compound L20 U2OS 48 712 SmallIrregular @@ -599,6 +5909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.6918367346938775 2.1245075728716683e-112 BR00117012 AMG900 final compound N09 U2OS 48 490 SmallIrregular 0.6885011733496582 4.001892316213354e-110 BR00117012 danusertib final compound N18 U2OS 48 484 SmallIrregular 0.6598109064838464 5.561123328327581e-107 BR00117011 danusertib final compound E05 U2OS 48 516 SmallIrregular +0.617958584831598 4.689310884666711e-100 BR00117010 danusertib final compound N18 U2OS 48 556 SmallIrregular +0.6378322532168686 4.880632291369098e-97 BR00117013 danusertib final compound E05 U2OS 48 504 SmallIrregular +0.5780625042370009 2.411828457803206e-92 BR00117010 PF-431396 final compound L20 U2OS 48 596 SmallIrregular +0.6174108216432865 2.380539093220247e-89 BR00117012 danusertib final compound E05 U2OS 48 500 SmallIrregular +0.5923264717305665 2.7648332640272015e-88 BR00117011 danusertib final compound N18 U2OS 48 536 SmallIrregular +0.6350762527233116 2.461429059532334e-87 BR00117013 danusertib final compound N18 U2OS 48 456 SmallIrregular +0.548951048951049 1.643387344441078e-79 BR00117011 fludarabine-phosphate final compound N12 U2OS 48 572 SmallIrregular +0.5518438970890646 7.672520629818229e-78 BR00117012 fludarabine-phosphate final compound N12 U2OS 48 554 SmallIrregular +0.5453212950020777 4.7378534138992865e-71 BR00117010 fludarabine-phosphate final compound N12 U2OS 48 514 SmallIrregular +0.5418964460784313 3.2761387369798704e-69 BR00117013 fludarabine-phosphate final compound N12 U2OS 48 510 SmallIrregular +0.5699685534591195 1.7173317785618553e-64 BR00117011 epothilone-b final compound F07 U2OS 48 426 SmallIrregular +0.5202577400597203 9.981659889193388e-63 BR00117010 epothilone-b final compound F07 U2OS 48 504 SmallIrregular +0.25739041794087664 1.678576949043668e-57 BR00117011 AC-710 final compound I03 U2OS 48 1962 SmallIrregular +0.2772192915284041 1.986206628384901e-57 BR00117013 AC-710 final compound I03 U2OS 48 1680 SmallIrregular +0.4820316721393242 5.113421383773903e-52 BR00117010 KG-5 final compound C13 U2OS 48 490 SmallIrregular +0.2669701356380156 5.2331098449440536e-51 BR00117010 RKI-1447 final compound J04 U2OS 48 1612 SmallIrregular +0.2664188351920694 9.08347683835175e-51 BR00117010 AC-710 final compound I03 U2OS 48 1614 SmallIrregular +0.46323146084394246 2.8298735243319046e-50 BR00117012 epothilone-b final compound F07 U2OS 48 514 SmallIrregular +0.47920688545688545 7.452532688259497e-47 BR00117013 epothilone-b final compound F07 U2OS 48 444 SmallIrregular +0.32883170143044954 1.159491833947875e-43 BR00117010 deferasirox final compound L14 U2OS 48 904 SmallIrregular +0.25830714855987635 2.0724366804081085e-43 BR00117012 AC-710 final compound I03 U2OS 48 1462 SmallIrregular +0.3742870463566925 6.069091515577421e-43 BR00117012 SKLB1002 final compound P17 U2OS 48 678 SmallIrregular +0.33444845889647173 1.4437713215175904e-42 BR00117013 deferasirox final compound L14 U2OS 48 846 SmallIrregular +0.5635369687030204 5.714346209682512e-40 BR00117013 delanzomib final compound L11 U2OS 48 270 SmallIrregular +0.6448717948717949 3.869402451102691e-39 BR00117013 thiostrepton final compound B02 U2OS 48 200 SmallIrregular +0.671425910981439 5.5801421173782745e-39 BR00117012 thiostrepton final compound B02 U2OS 48 178 SmallIrregular +0.23584454338179653 1.3294131379797986e-38 BR00117011 RKI-1447 final compound J04 U2OS 48 1558 SmallIrregular +0.6032142857142857 2.1373611644651314e-38 BR00117010 delanzomib final compound L11 U2OS 48 224 SmallIrregular +0.25713511735454037 7.853273204183183e-38 BR00117013 RKI-1447 final compound J04 U2OS 48 1288 SmallIrregular +0.2515850550837898 8.712273904072387e-38 BR00117012 fludarabine final compound B06 U2OS 48 1342 SmallIrregular +0.4025 1.2179686780611955e-36 BR00117011 GSK1070916 final compound C04 U2OS 48 500 SmallIrregular +0.2962544610373861 1.2412791705342915e-36 BR00117011 deferasirox final compound L14 U2OS 48 930 SmallIrregular +0.45545039164490864 1.3802376641423736e-36 BR00117012 KG-5 final compound C13 U2OS 48 384 SmallIrregular +0.23829489867225717 3.94594619335696e-36 BR00117012 RKI-1447 final compound J04 U2OS 48 1434 SmallIrregular +0.5609756097560976 5.371176756863495e-36 BR00117010 AZD7762 final compound K11 U2OS 48 246 SmallIrregular +0.29605263157894735 1.202764971481748e-35 BR00117012 deferasirox final compound L14 U2OS 48 912 SmallIrregular +0.6541287099617984 9.768895083662027e-34 BR00117013 puromycin final compound C22 U2OS 48 164 SmallIrregular +0.25402101014897027 2.371689796089173e-33 BR00117010 polydatin final compound K08 U2OS 48 1160 SmallIrregular +0.6086135895676047 1.0027213782426124e-32 BR00117011 delanzomib final compound L11 U2OS 48 186 SmallIrregular +0.2745807264511644 2.8412844663318635e-32 BR00117013 polydatin final compound K08 U2OS 48 960 SmallIrregular +0.5403162896248493 3.0944239330644245e-32 BR00117013 BVT-948 final compound B12 U2OS 48 236 SmallIrregular +0.19566237137874706 6.806079686023461e-32 BR00117012 PETCM final compound I04 U2OS 48 1874 SmallIrregular +0.2109539113488214 1.6646571591652244e-31 BR00117011 NVS-PAK1-1 final compound N14 U2OS 48 1590 SmallIrregular +0.42062907637281716 1.72378075536333e-31 BR00117013 KG-5 final compound C13 U2OS 48 388 SmallIrregular +0.40010307892260116 9.141924868979829e-31 BR00117011 ixabepilone final compound J21 U2OS 48 424 SmallIrregular +0.4166666666666667 3.0719980290074728e-30 BR00117011 KG-5 final compound C13 U2OS 48 384 SmallIrregular +0.401728342948267 3.1029665936034946e-30 BR00117013 GSK1070916 final compound C04 U2OS 48 414 SmallIrregular +0.5721537345902828 4.3310437467203344e-30 BR00117012 delanzomib final compound L11 U2OS 48 196 SmallIrregular +0.38236938925680647 4.803646446694585e-30 BR00117013 SKLB1002 final compound P17 U2OS 48 450 SmallIrregular +0.3329194698697774 1.901851838919055e-29 BR00117010 SKLB1002 final compound P17 U2OS 48 590 SmallIrregular +0.38967136150234744 3.0635095013936563e-29 BR00117010 GSK1070916 final compound C04 U2OS 48 426 SmallIrregular +0.5722300140252454 2.130531731285549e-28 BR00117013 NSC-632839 final compound M16 U2OS 48 184 SmallIrregular +0.6397058823529411 1.678245455759661e-27 BR00117010 thiostrepton final compound B02 U2OS 48 144 SmallIrregular +0.3766090636572033 1.763444369269789e-27 BR00117012 GSK1070916 final compound C04 U2OS 48 424 SmallIrregular +0.198360548232671 2.4235609161029806e-27 BR00117013 NVS-PAK1-1 final compound N14 U2OS 48 1560 SmallIrregular +0.1998550657201993 4.4799424125434526e-27 BR00117013 fludarabine final compound B06 U2OS 48 1524 SmallIrregular +0.6486425339366516 4.883299261286497e-27 BR00117011 NSC-632839 final compound M16 U2OS 48 136 SmallIrregular +0.6948270584634221 6.292964870952473e-27 BR00117012 ponatinib final compound C20 U2OS 48 108 SmallIrregular +0.41369047619047616 4.003392357078262e-26 BR00117012 ixabepilone final compound J21 U2OS 48 336 SmallIrregular +0.18270657992388953 5.798165627293801e-26 BR00117010 ingenol-mebutate final compound M11 U2OS 48 1744 SmallIrregular +0.5019689987431923 9.914649040940976e-26 BR00117012 BVT-948 final compound B12 U2OS 48 220 SmallIrregular +0.2503622608956931 1.9107835812479374e-25 BR00117010 JTE-607 final compound C14 U2OS 48 908 SmallIrregular +0.5118370079869913 4.186276343827866e-25 BR00117012 AZD7762 final compound K11 U2OS 48 206 SmallIrregular +0.4271760797342193 4.949037519285423e-25 BR00117010 ixabepilone final compound J21 U2OS 48 300 SmallIrregular +0.5924657534246576 6.572179108229908e-25 BR00117012 NSC-632839 final compound M16 U2OS 48 152 SmallIrregular +0.2819327731092437 2.1194681910110252e-24 BR00117011 SKLB1002 final compound P17 U2OS 48 680 SmallIrregular +0.5096139055529918 3.921129562773236e-24 BR00117011 AZD7762 final compound K11 U2OS 48 198 SmallIrregular +0.631864406779661 2.3052877860571732e-23 BR00117011 NSC-663284 final compound G06 U2OS 48 118 SmallIrregular +0.19866746429196847 5.496446154178438e-23 BR00117012 NVS-PAK1-1 final compound N14 U2OS 48 1306 SmallIrregular +0.25000609666878015 9.661918608893888e-23 BR00117011 JTE-607 final compound C14 U2OS 48 812 SmallIrregular +0.6099806201550387 1.0876264030147245e-22 BR00117010 AZD7762 final compound I05 U2OS 48 128 SmallIrregular +0.2747747747747748 1.572707736967481e-22 BR00117013 JTE-607 final compound C14 U2OS 48 666 SmallIrregular +0.18563417325453088 1.9460035876436104e-22 BR00117010 NVS-PAK1-1 final compound N14 U2OS 48 1456 SmallIrregular +0.24986760698001834 4.677171509005226e-22 BR00117010 KU-60019 final compound I07 U2OS 48 786 SmallIrregular +0.16931780116243414 1.6194745783250446e-21 BR00117012 MCOPPB final compound B17 U2OS 48 1678 SmallIrregular +0.35957262225469155 2.9036333625462666e-21 BR00117012 GK921 final compound H24 U2OS 48 362 SmallIrregular +0.22803242343074406 7.836722463679533e-21 BR00117010 FK-866 final compound L09 U2OS 48 892 SmallIrregular +0.17290322580645162 1.2071563732546488e-20 BR00117010 lonafarnib final compound J06 U2OS 48 1550 SmallIrregular +0.24345549738219896 2.813377017601945e-20 BR00117010 BMS-536924 final compound B15 U2OS 48 764 SmallIrregular +0.22899835619391523 2.890364237339095e-20 BR00117013 FK-866 final compound L09 U2OS 48 860 SmallIrregular +0.16041152230488717 6.217175183865034e-20 BR00117011 GNF-5837 final compound A10 U2OS 48 1734 SmallIrregular +0.4994396189408798 9.507323303221594e-20 BR00117013 NSC-663284 final compound G06 U2OS 48 166 SmallIrregular +0.15876165944659096 9.656593710348774e-20 BR00117012 ingenol-mebutate final compound M11 U2OS 48 1752 SmallIrregular +0.2419572504462148 1.279169042131581e-19 BR00117011 BMS-536924 final compound B15 U2OS 48 744 SmallIrregular +0.2888105138105138 1.553526887748526e-19 BR00117011 menadione final compound M12 U2OS 48 518 SmallIrregular +0.19800759013282732 4.19297058455221e-19 BR00117011 NNC-55-0396 final compound A16 U2OS 48 1088 SmallIrregular +0.4876190476190476 4.745316122044633e-19 BR00117013 AZD7762 final compound I05 U2OS 48 168 SmallIrregular +0.5266463646745337 5.646940924483369e-19 BR00117011 BVT-948 final compound B12 U2OS 48 148 SmallIrregular +0.16960197587156836 9.786540175589143e-19 BR00117010 fludarabine final compound B06 U2OS 48 1452 SmallIrregular +0.14873417721518986 1.053161073630937e-18 BR00117013 ingenol-mebutate final compound M11 U2OS 48 1896 SmallIrregular 0.2728612162262431 5.152551256976878e-18 BR00118041 HDAC3 final crispr K19 A549 96 531 ADCCM 0.14830291513256 3.281603910389643e-17 BR00118044 GJB4 final crispr N01 A549 96 1740 ADCCM 0.2612377920003431 2.0906753686353878e-16 BR00118041 MMP2 final crispr E07 A549 96 527 ADCCM @@ -609,6 +6009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2673913043478261 7.215851910261498e-15 BR00118041 OPRL1 final crispr A11 A549 96 460 ADCCM 0.1029771142904628 8.383981416881428e-15 BR00118041 UGT1A9 final crispr J01 A549 96 3112 ADCCM 0.2627118644067797 1.0033371335543474e-14 BR00118043 TUBB3 final crispr K11 A549 96 472 ADCCM +0.11921876538477934 1.0189171850927657e-14 BR00118044 PTK2B final crispr N15 A549 96 2302 ADCCM +0.18777141324831845 2.4394278670065004e-14 BR00118041 HDAC3 final crispr G07 A549 96 897 ADCCM +0.19821495619524407 3.330492112374281e-14 BR00118041 CHRM3 final crispr B21 A549 96 800 ADCCM +0.13092645209093326 3.7525032764125165e-14 BR00118043 GJB4 final crispr N01 A549 96 1829 ADCCM +0.19679090115901313 3.9802611622001654e-14 BR00118043 TGFBR1 final crispr B08 A549 96 802 ADCCM +0.22671327308744904 1.3745529385406755e-13 BR00118041 CDK7 final crispr E12 A549 96 581 ADCCM +0.13112553941169483 1.5372718468316858e-13 BR00118044 LPAR1 final crispr L01 A549 96 1740 ADCCM +0.12894299944659657 1.6613071007990442e-13 BR00118044 HSD11B1 final crispr O01 A549 96 1807 ADCCM +0.3111184939091916 2.374500643206778e-13 BR00118043 RPL23A final crispr G14 A549 96 301 ADCCM +0.3264653836129439 2.4601202230366003e-13 BR00118043 RPL3 final crispr K04 A549 96 269 ADCCM +0.3524701335860134 2.8970655871531424e-13 BR00118043 RPL23A final crispr M18 A549 96 233 ADCCM +0.2156148867313916 4.5292774407130563e-13 BR00118041 BTK final crispr D24 A549 96 618 ADCCM +0.2495543930325909 5.981676989580319e-13 BR00118041 ASIC1 final crispr M20 A549 96 453 ADCCM +0.20658682634730538 6.911868322159513e-13 BR00118041 VEGFA final crispr H02 A549 96 668 ADCCM +0.17894474610050232 7.268610265010856e-13 BR00118041 SCNN1G final crispr G24 A549 96 888 ADCCM +0.21775544388609716 8.287510571979533e-13 BR00118041 HIF1A final crispr M24 A549 96 597 ADCCM +0.2003500975363985 1.7231041547816704e-12 BR00118041 HBB final crispr M08 A549 96 681 ADCCM +0.18605984179754673 1.9203229757381207e-12 BR00118043 CSK final crispr B11 A549 96 792 ADCCM +0.12133947572451172 2.3837055799441284e-12 BR00118043 LPAR1 final crispr L01 A549 96 1855 ADCCM +0.10718835304822566 3.2011032232168296e-12 BR00118041 TUBB final crispr J17 A549 96 2352 ADCCM +0.24162998532746433 6.798369324584873e-12 BR00118044 RPL3 final crispr K04 A549 96 441 ADCCM +0.3117800245098039 1.3232364404610603e-11 BR00118041 AURKB final crispr C13 A549 96 255 ADCCM +0.18498862636752222 1.4140994945401957e-11 BR00118041 IMPDH1 final crispr F15 A549 96 739 ADCCM +0.1097750175582579 1.551894189053702e-11 BR00118041 CDK2 final crispr L19 A549 96 2107 ADCCM +0.279186320754717 1.7301637750526014e-11 BR00118041 CDK4 final crispr B15 A549 96 318 ADCCM +0.1858747143459626 3.051089800914372e-11 BR00118041 HRH4 final crispr A08 A549 96 715 ADCCM +0.39271255060728744 3.711398926503315e-11 BR00118042 AURKB final crispr C13 A549 96 152 ADCCM +0.215292725120641 4.2799161032148953e-11 BR00118041 ABL1 final crispr P20 A549 96 523 ADCCM +0.19558359621451105 5.11241778171032e-11 BR00118041 CHEK2 final crispr M07 A549 96 634 ADCCM +0.21823514359388224 5.235316195893532e-11 BR00118041 COMT final crispr A12 A549 96 505 ADCCM +0.24721120803595031 5.3783005875651164e-11 BR00118041 PAK4 final crispr M16 A549 96 388 ADCCM +0.1809987957248231 6.599934237123744e-11 BR00118043 SLC7A11 final crispr P05 A549 96 728 ADCCM +0.12010546193038088 7.382376219655907e-11 BR00118044 AKR1B1 final crispr L21 A549 96 1649 ADCCM +0.20239750139914425 7.851370485168058e-11 BR00118043 SLCO2B1 final crispr A21 A549 96 574 ADCCM +0.11798907217207871 8.179445664900236e-11 BR00118044 AKT1 final crispr J19 A549 96 1700 ADCCM +0.1786014382836627 8.853387464782502e-11 BR00118043 TUBB4B final crispr C04 A549 96 741 ADCCM +0.09344145028339851 9.526613549982236e-11 BR00118041 AGER final crispr J18 A549 96 2707 ADCCM +0.3756172377674697 1.0336783689165465e-10 BR00118041 RPL3 final crispr K04 A549 96 164 ADCCM +0.09725815833943115 1.2780737793262104e-10 BR00118041 AKR1B1 final crispr L21 A549 96 2467 ADCCM +0.20881815903476425 1.448354017635578e-10 BR00118043 CDK4 final crispr B15 A549 96 527 ADCCM +0.31251874062968515 1.4566128707535914e-10 BR00118042 SIRT2 final crispr P01 A549 96 230 ADCCM +0.1741130618489109 2.6711618309071145e-10 BR00118043 PARP3 final crispr F12 A549 96 740 ADCCM +0.11323635510549716 2.6998754341688564e-10 BR00118044 GAA final crispr L17 A549 96 1765 ADCCM +0.20868414265993113 2.7746339124936563e-10 BR00118043 OPRL1 final crispr A11 A549 96 511 ADCCM +0.1885594513746159 2.831436347818858e-10 BR00118041 CDK7 final crispr I14 A549 96 626 ADCCM +0.17314271749755622 2.9270769817778807e-10 BR00118041 HSD11B1 final crispr O23 A549 96 744 ADCCM +0.09594576382418947 2.983080773628415e-10 BR00118041 PORCN final crispr L13 A549 96 2443 ADCCM +0.16605166051660517 3.3596179948821126e-10 BR00118043 CA14 final crispr C19 A549 96 813 ADCCM +0.22544699872286078 3.47736773040546e-10 BR00118041 AVPR1A final crispr J07 A549 96 432 ADCCM +0.154225302889096 4.175212264128131e-10 BR00118041 PTPN2 final crispr B12 A549 96 925 ADCCM +0.17309553978239012 4.647133889867291e-10 BR00118041 TGFBR1 final crispr B08 A549 96 729 ADCCM +0.1913477537437604 4.935029556134481e-10 BR00118041 SLC7A11 final crispr P05 A549 96 601 ADCCM +0.11183180189268009 5.313803810710574e-10 BR00118044 LYN final crispr N13 A549 96 1748 ADCCM +0.1916179018037972 5.622834877755751e-10 BR00118041 AKR1C1 final crispr B13 A549 96 589 ADCCM +0.15818874796889823 7.983389561653225e-10 BR00118041 HSP90AA1 final crispr I04 A549 96 857 ADCCM +0.10579650834445109 8.282302792057393e-10 BR00118043 ELANE final crispr N19 A549 96 1915 ADCCM +0.08691362131193932 8.573465784951779e-10 BR00118041 FOXM1 final crispr F23 A549 96 2840 ADCCM +0.23929544569871544 1.1100018809611136e-09 BR00118041 TUBB3 final crispr K11 A549 96 367 ADCCM +0.10845790183429395 1.8562789321489587e-09 BR00118043 HSD11B1 final crispr O01 A549 96 1752 ADCCM +0.22661020930111175 2.2296649324490557e-09 BR00118044 RPL23A final crispr G14 A549 96 391 ADCCM +0.19445609033484265 2.3981585732482183e-09 BR00118041 RNASE1 final crispr I13 A549 96 534 ADCCM +0.12327782544438505 2.639092384332325e-09 BR00118041 OPRM1 final crispr P22 A549 96 1336 ADCCM +0.15935075093867335 2.672927534911611e-09 BR00118041 PTGIS final crispr I16 A549 96 800 ADCCM +0.11424150801372794 3.177504957615114e-09 BR00118044 UGT1A9 final crispr J01 A549 96 1538 ADCCM +0.10924548879635138 3.1809168781653572e-09 BR00118044 MET final crispr H13 A549 96 1680 ADCCM +0.22567538248114716 3.2932432580386647e-09 BR00118041 CA5A final crispr M01 A549 96 389 ADCCM +0.15490964638395688 3.9376903233115345e-09 BR00118041 TBXAS1 final crispr E24 A549 96 829 ADCCM +0.17084890199934447 4.082999445584651e-09 BR00118043 FFAR2 final crispr A06 A549 96 678 ADCCM +0.10514665190924184 4.084221411597916e-09 BR00118044 PORCN final crispr L13 A549 96 1807 ADCCM +0.2562680972368746 4.0933548779218625e-09 BR00118041 CCND1 final crispr B23 A549 96 299 ADCCM +0.1906175486335869 4.597517349508382e-09 BR00118043 CDK2 final crispr F08 A549 96 542 ADCCM +0.10407748322431029 5.89568690743129e-09 BR00118041 KRAS final crispr F07 A549 96 1797 ADCCM +0.18418274570107032 6.075078123789182e-09 BR00118042 SLC29A1 final crispr E03 A549 96 573 ADCCM +0.14670441475714413 8.044433733782543e-09 BR00118041 TUBB4B final crispr C04 A549 96 890 ADCCM +0.10937482963422175 8.40852491302325e-09 BR00118044 OPRM1 final crispr P22 A549 96 1604 ADCCM +0.15870206177940757 8.428646272242178e-09 BR00118043 ALDH2 final crispr A10 A549 96 754 ADCCM +0.16344215054816774 1.1944878510331309e-08 BR00118041 KCNN1 final crispr D01 A549 96 702 ADCCM +0.18796992481203006 1.2492256574744733e-08 BR00118043 HPGDS final crispr B19 A549 96 532 ADCCM +0.24960489246203532 1.278310251110294e-08 BR00118041 CDK2 final crispr F08 A549 96 297 ADCCM +0.08501976491402408 1.291759486265349e-08 BR00118041 RGS4 final crispr N11 A549 96 2591 ADCCM +0.20729154835883373 1.2925113649085003e-08 BR00118042 HRH4 final crispr H24 A549 96 429 ADCCM +0.13883018478905182 1.4107117202187283e-08 BR00118041 CA14 final crispr C19 A549 96 966 ADCCM +0.2801724137931034 2.0084628558912955e-08 BR00118044 RPL23A final crispr M18 A549 96 232 ADCCM +0.15074293995313692 2.3613797830437534e-08 BR00118041 IL1B final crispr H18 A549 96 799 ADCCM +0.16365258907257435 2.4268810216074293e-08 BR00118043 HDAC3 final crispr K19 A549 96 670 ADCCM +0.13222928727341748 2.6311579776429147e-08 BR00118041 KCNJ1 final crispr E14 A549 96 1025 ADCCM +0.1534989563015433 2.6856039721285918e-08 BR00118043 TGM2 final crispr B09 A549 96 765 ADCCM +0.0992980826394899 2.7562227026304696e-08 BR00118044 AKR1B1 final crispr H17 A549 96 1818 ADCCM +0.18945553091894554 3.107306745547555e-08 BR00118041 CDK9 final crispr M04 A549 96 495 ADCCM +0.23188726167449572 3.228646467462363e-08 BR00118042 TUBB final crispr K13 A549 96 330 ADCCM 0.3542150284605845 3.341108540716063e-30 BR00118044 AURKB final crispr C13 A549 96 533 Anaphase 0.3191732240161003 1.1487181256148245e-26 BR00118043 AURKB final crispr C13 A549 96 577 Anaphase 0.5531376518218624 2.538282116906189e-22 BR00118042 AURKB final crispr C13 A549 96 152 Anaphase @@ -619,6 +6109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.33797197353055664 4.896573269360509e-19 BR00118041 TUBB3 final crispr K11 A549 96 367 Anaphase 0.2391304347826087 7.200546151559388e-19 BR00118043 PPAT final crispr E13 A549 96 736 Anaphase 0.2485672082717873 7.369786223579285e-19 BR00118041 FOXM1 final crispr A19 A549 96 675 Anaphase +0.2966101694915254 1.0293072128516898e-18 BR00118043 TUBB3 final crispr K11 A549 96 472 Anaphase +0.3673421926910299 1.8313892891365778e-18 BR00118043 RPL23A final crispr G14 A549 96 301 Anaphase +0.25778881268765336 1.6105399115495467e-17 BR00118041 CDK7 final crispr E12 A549 96 581 Anaphase +0.3103504954010217 3.9018778921222224e-17 BR00118041 CA5A final crispr M01 A549 96 389 Anaphase +0.34983498349834985 7.566549678812798e-17 BR00118044 PLK1 final crispr F13 A549 96 303 Anaphase +0.3656716417910448 2.52356100742327e-16 BR00118042 CDK7 final crispr I14 A549 96 268 Anaphase +0.3577665441176471 5.8518450740505885e-15 BR00118041 AURKB final crispr C13 A549 96 255 Anaphase +0.3067241066099188 1.024826235701655e-14 BR00118042 PPAT final crispr E13 A549 96 339 Anaphase +0.09774136121931436 2.1709823117700002e-13 BR00118041 UGT1A9 final crispr J01 A549 96 3112 Anaphase +0.20732236166987975 2.5024910912233935e-13 BR00118043 S1PR1 final crispr P23 A549 96 682 Anaphase +0.584493670886076 5.086764929370121e-13 BR00118042 RPL23A final crispr G14 A549 96 80 Anaphase +0.2671720862257947 6.854983608538123e-13 BR00118044 RPL23A final crispr G14 A549 96 391 Anaphase +0.323675688179505 8.829600839242842e-13 BR00118042 TUBB3 final crispr K11 A549 96 262 Anaphase +0.24565217391304348 1.36400097577589e-12 BR00118041 OPRL1 final crispr A11 A549 96 460 Anaphase +0.22202486678507993 1.4386234848662042e-12 BR00118042 PPAT final crispr G13 A549 96 563 Anaphase +0.2100550964187328 2.987566486941596e-12 BR00118043 FOXM1 final crispr A19 A549 96 612 Anaphase +0.2128352490421456 5.806949512078419e-12 BR00118041 HSP90AB1 final crispr B04 A549 96 576 Anaphase +0.169219297026074 1.2875223459540965e-11 BR00118041 TUBB4B final crispr C04 A549 96 890 Anaphase +0.21550296508551678 1.8205382681491273e-11 BR00118043 CDK2 final crispr F08 A549 96 542 Anaphase +0.23735138140449918 2.8504954499304382e-11 BR00118042 CTSG final crispr L12 A549 96 432 Anaphase +0.28462538472649695 2.903348160950532e-11 BR00118044 PLK1 final crispr G09 A549 96 301 Anaphase +0.519723092998955 2.913662069612716e-11 BR00118042 PLK1 final crispr G09 A549 96 87 Anaphase +0.18523328004393924 3.106059723325563e-11 BR00118041 HRH4 final crispr A08 A549 96 715 Anaphase +0.3510081318926145 6.77533208826165e-11 BR00118042 CDK2 final crispr F08 A549 96 188 Anaphase +0.20467130821325785 8.379936867759647e-11 BR00118041 FLT3 final crispr G16 A549 96 563 Anaphase +0.2362469437652812 1.6588381027064997e-10 BR00118041 PPAT final crispr E13 A549 96 408 Anaphase +0.19297212187536641 3.1437174296098375e-10 BR00118041 CYP1A2 final crispr M15 A549 96 598 Anaphase +0.1855888237901825 3.459515517862064e-10 BR00118044 PPAT final crispr E13 A549 96 647 Anaphase +0.3534611723106215 3.615530868900367e-10 BR00118042 DDR2 final crispr A03 A549 96 172 Anaphase +0.2723493437779152 3.744362963666176e-10 BR00118041 CDK2 final crispr F08 A549 96 297 Anaphase +0.44036697247706424 7.003146055137636e-10 BR00118042 RPL3 final crispr K04 A549 96 109 Anaphase +0.20279180279180278 7.10171039011127e-10 BR00118042 CDK7 final crispr E12 A549 96 518 Anaphase +0.3017241379310345 1.010698484672172e-09 BR00118044 RPL23A final crispr M18 A549 96 232 Anaphase +0.18597962135299426 1.1613241949657914e-09 BR00118041 CDK9 final crispr I20 A549 96 609 Anaphase +0.1669881425769653 1.4993946751559481e-09 BR00118043 IMPDH1 final crispr F15 A549 96 745 Anaphase +0.16824966078697423 1.5971865054822012e-09 BR00118043 S1PR1 final crispr A18 A549 96 737 Anaphase +0.16050135207885993 1.6004331122789364e-09 BR00118043 TGFBR1 final crispr B08 A549 96 802 Anaphase +0.18425460636515914 2.855930147802716e-09 BR00118041 HIF1A final crispr M24 A549 96 597 Anaphase +0.28834923800028484 2.9710637755133928e-09 BR00118042 UGT1A9 final crispr J01 A549 96 236 Anaphase +0.16331994645247658 4.117945394732823e-09 BR00118043 CDK7 final crispr I14 A549 96 747 Anaphase +0.23388156865199838 4.275489120010507e-09 BR00118042 FOXM1 final crispr A19 A549 96 359 Anaphase +0.18437801291204434 4.997624172973923e-09 BR00118042 SLC29A1 final crispr E03 A549 96 573 Anaphase +0.17100372576578987 5.040718691614618e-09 BR00118043 HDAC3 final crispr K19 A549 96 670 Anaphase +0.17345536342711484 5.3747235584461854e-09 BR00118041 CSF1R final crispr J15 A549 96 648 Anaphase +0.15176470588235294 5.897670591956234e-09 BR00118043 FGF1 final crispr I19 A549 96 850 Anaphase +0.17538308133737612 6.687191392986151e-09 BR00118041 CDK7 final crispr I14 A549 96 626 Anaphase +0.15120202834754584 7.4113612332865315e-09 BR00118043 CDK7 final crispr E12 A549 96 841 Anaphase +0.200836820083682 7.57534109300982e-09 BR00118042 PIK3CG final crispr I08 A549 96 478 Anaphase +0.1604882205851022 1.0536392825414537e-08 BR00118041 TGFBR1 final crispr B08 A549 96 729 Anaphase +0.27667397537527405 1.0582672920617746e-08 BR00118042 CA5A final crispr M01 A549 96 245 Anaphase +0.192593947523525 1.5471043974594167e-08 BR00118043 DHH final crispr F05 A549 96 497 Anaphase +0.17341977309562398 1.614499189601531e-08 BR00118044 FOXM1 final crispr A19 A549 96 617 Anaphase +0.2459016393442623 1.6683679878217477e-08 BR00118041 FFAR2 final crispr A24 A549 96 305 Anaphase +0.1872146118721461 2.3394750330687395e-08 BR00118043 OPRL1 final crispr A11 A549 96 511 Anaphase +0.17127893532890182 3.2219815750096244e-08 BR00118042 PRKCE final crispr I17 A549 96 601 Anaphase +0.39344799344799347 3.941799011345063e-08 BR00118042 CACNG1 final crispr L02 A549 96 111 Anaphase +0.2289951183568205 4.831122351428874e-08 BR00118042 TUBB final crispr K13 A549 96 330 Anaphase +0.1503154433062036 5.304451119743867e-08 BR00118041 CDC25A final crispr C14 A549 96 764 Anaphase +0.18048404998030862 5.3175336158562205e-08 BR00118043 CDK4 final crispr B15 A549 96 527 Anaphase +0.1677469557371214 7.08708516044054e-08 BR00118043 CSF1R final crispr J15 A549 96 603 Anaphase +0.17853250284987332 7.398416931004287e-08 BR00118041 MMP2 final crispr E07 A549 96 527 Anaphase +0.1903156731366996 7.564125621101773e-08 BR00118044 CDK4 final crispr B15 A549 96 467 Anaphase +0.19088401659735002 9.765924806802868e-08 BR00118041 ASIC1 final crispr M20 A549 96 453 Anaphase +0.1499661297606503 1.1854486778116307e-07 BR00118043 SLC7A11 final crispr P05 A549 96 728 Anaphase +0.15901926030958288 1.2414301911977948e-07 BR00118041 COMT final crispr M02 A549 96 650 Anaphase +0.194125159642401 1.257906276939388e-07 BR00118041 AVPR1A final crispr J07 A549 96 432 Anaphase +0.2994034655809109 1.2822910485927076e-07 BR00118042 RGS4 final crispr N11 A549 96 179 Anaphase +0.17407407407407408 1.4622836857986673e-07 BR00118041 FGF1 final crispr J12 A549 96 540 Anaphase +0.1804639545513909 1.468097846724917e-07 BR00118042 FGF1 final crispr J12 A549 96 494 Anaphase +0.2295538523952063 1.6176912137034926e-07 BR00118042 ALDH2 final crispr A10 A549 96 301 Anaphase +0.24535315985130113 1.6200007110321791e-07 BR00118041 RPL23A final crispr G14 A549 96 269 Anaphase +0.08826663827265657 1.6787660599568695e-07 BR00118041 AKT1 final crispr J19 A549 96 2080 Anaphase +0.17848945928390056 1.7098553259268694e-07 BR00118041 COMT final crispr A12 A549 96 505 Anaphase +0.14944611489159676 1.9773545023211223e-07 BR00118042 NAMPT final crispr I09 A549 96 710 Anaphase +0.17055693871286792 2.3053272953309542e-07 BR00118043 CDC25A final crispr D06 A549 96 545 Anaphase +0.1573208722741433 2.3825175955349393e-07 BR00118041 ADORA2A final crispr O14 A549 96 642 Anaphase +0.1565683777429467 2.530762853115115e-07 BR00118041 PPAT final crispr G13 A549 96 640 Anaphase +0.21978157644824312 2.581534593818936e-07 BR00118042 TBXAS1 final crispr P08 A549 96 325 Anaphase +0.17195177208558118 2.625455750430303e-07 BR00118042 CA14 final crispr C19 A549 96 532 Anaphase +0.18780655755071773 3.0795971716658453e-07 BR00118042 DHH final crispr F05 A549 96 434 Anaphase +0.1335879092549626 3.3062678686879707e-07 BR00118043 JAK1 final crispr J09 A549 96 862 Anaphase +0.21098265895953758 3.728121975969944e-07 BR00118042 HSP90AB1 final crispr B04 A549 96 346 Anaphase +0.3584847073435802 3.9115826440209154e-07 BR00118042 CDK2 final crispr L19 A549 96 113 Anaphase +0.15052160953800298 4.768726459204774e-07 BR00118041 GJB4 final crispr H01 A549 96 671 Anaphase +0.12491793500881797 4.860010478660666e-07 BR00118041 CYP2A6 final crispr O04 A549 96 967 Anaphase +0.18100024636610001 5.87825166569795e-07 BR00118042 ITGB2 final crispr A17 A549 96 450 Anaphase +0.1400523560209424 5.966515698866512e-07 BR00118042 JAK1 final crispr M21 A549 96 764 Anaphase +0.0873212083038081 6.205820710817354e-07 BR00118041 GJB4 final crispr N01 A549 96 1954 Anaphase +0.13603959711071908 6.659182775848844e-07 BR00118043 KCNJ1 final crispr E14 A549 96 797 Anaphase +0.25498712998712997 7.535550887279561e-07 BR00118042 CDK4 final crispr P03 A549 96 222 Anaphase 0.19431255956789162 9.975007608495381e-46 BR00118041 LYN final crispr N13 A549 96 2739 Apoptosis 0.19169420915490806 2.063059106554516e-37 BR00118044 PTK2B final crispr N15 A549 96 2302 Apoptosis 0.1723635527973029 6.7310591859381975e-37 BR00118041 MAPK8 final crispr D07 A549 96 2807 Apoptosis @@ -629,6 +6209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.417425492606789 6.736086821109355e-31 BR00118041 CA5A final crispr M01 A549 96 389 Apoptosis 0.3847826086956522 9.563636115103512e-31 BR00118041 OPRL1 final crispr A11 A549 96 460 Apoptosis 0.14898966513174705 1.4562431161809127e-30 BR00118041 UGT1A9 final crispr J01 A549 96 3112 Apoptosis +0.5218958437842558 1.5127304479194812e-29 BR00118043 RPL23A final crispr M18 A549 96 233 Apoptosis +0.3728414442700157 5.289546705183493e-28 BR00118044 RPL3 final crispr K04 A549 96 441 Apoptosis +0.4476854928017719 9.52838903539854e-28 BR00118043 RPL23A final crispr G14 A549 96 301 Apoptosis +0.35842257548751094 1.5782668178093066e-26 BR00118041 ASIC1 final crispr M20 A549 96 453 Apoptosis +0.1432293088811331 7.191127955715193e-26 BR00118041 FOXM1 final crispr F23 A549 96 2840 Apoptosis +0.27874733961690484 5.935650555853258e-25 BR00118041 HRH4 final crispr A08 A549 96 715 Apoptosis +0.26249822094886854 7.145666368161556e-25 BR00118043 TGFBR1 final crispr B08 A549 96 802 Apoptosis +0.16801389241292006 3.992196087819428e-24 BR00118043 ELANE final crispr N19 A549 96 1915 Apoptosis +0.4757496251874063 4.236902779432283e-24 BR00118042 SIRT2 final crispr P01 A549 96 230 Apoptosis +0.15861324146296646 1.3098153109766894e-23 BR00118041 CDK2 final crispr L19 A549 96 2107 Apoptosis +0.14287162428580735 1.561313012141545e-23 BR00118041 RGS4 final crispr N11 A549 96 2591 Apoptosis +0.3054841240066846 7.979656923932742e-23 BR00118043 CDC25A final crispr D06 A549 96 545 Apoptosis +0.3539981209875254 1.87992955211266e-22 BR00118044 RPL23A final crispr G14 A549 96 391 Apoptosis +0.30626400368786116 1.985531982665185e-22 BR00118041 MMP2 final crispr E07 A549 96 527 Apoptosis +0.1734523333465165 2.9817833506593476e-22 BR00118044 CACNG1 final crispr N23 A549 96 1653 Apoptosis +0.268180924287119 7.023912383209919e-22 BR00118043 FFAR2 final crispr A06 A549 96 678 Apoptosis +0.3317049808429119 1.0275525251897886e-21 BR00118041 AVPR1A final crispr J07 A549 96 432 Apoptosis +0.2568169714524354 1.6382138616081351e-21 BR00118044 GRIN2A final crispr A23 A549 96 722 Apoptosis +0.30145133387963213 1.6981844088771374e-21 BR00118041 ABL1 final crispr P20 A549 96 523 Apoptosis +0.2870223139701757 3.769138965512471e-21 BR00118041 TGFBR1 final crispr P24 A549 96 569 Apoptosis +0.3901639344262295 4.238566514558048e-21 BR00118041 FFAR2 final crispr A24 A549 96 305 Apoptosis +0.1321707582576839 4.451247142871839e-21 BR00118041 AGER final crispr J18 A549 96 2707 Apoptosis +0.41044776119402987 1.3853679944107794e-20 BR00118042 CDK7 final crispr I14 A549 96 268 Apoptosis +0.15800173320388602 1.8920639652762445e-20 BR00118043 PTK2B final crispr N15 A549 96 1837 Apoptosis +0.28864403169171354 2.3747651406484853e-20 BR00118043 CDK2 final crispr F08 A549 96 542 Apoptosis +0.2704156684739209 2.6833171146876275e-20 BR00118041 BTK final crispr D24 A549 96 618 Apoptosis +0.3002906326849989 3.28164379097558e-20 BR00118043 DHH final crispr F05 A549 96 497 Apoptosis +0.137429589670263 7.812644585012901e-20 BR00118041 TUBB final crispr J17 A549 96 2352 Apoptosis +0.24234354194407456 9.266146236629041e-20 BR00118043 KCNMA1 final crispr A07 A549 96 751 Apoptosis +0.271356783919598 9.652634494354271e-20 BR00118041 HIF1A final crispr M24 A549 96 597 Apoptosis +0.40909926470588237 1.007972830079121e-19 BR00118041 AURKB final crispr C13 A549 96 255 Apoptosis +0.34134802527173097 1.760654387330627e-19 BR00118041 TUBB3 final crispr K11 A549 96 367 Apoptosis +0.28922237898026365 1.8948977847401804e-19 BR00118043 OPRL1 final crispr A11 A549 96 511 Apoptosis +0.2418478260869565 2.7011474990283205e-19 BR00118043 PPAT final crispr E13 A549 96 736 Apoptosis +0.28984508788851054 3.133288920575705e-19 BR00118041 COMT final crispr A12 A549 96 505 Apoptosis +0.28213566996478284 3.1342808069917595e-19 BR00118041 RNASE1 final crispr I13 A549 96 534 Apoptosis +0.2830367691811965 3.4223053103832953e-19 BR00118043 CDK4 final crispr B15 A549 96 527 Apoptosis +0.23999322595213007 6.742516240508481e-19 BR00118043 SLC7A11 final crispr P05 A549 96 728 Apoptosis +0.4038202030587328 8.015403497155091e-19 BR00118043 PLK1 final crispr G09 A549 96 251 Apoptosis +0.22445140882711165 8.259435051903063e-19 BR00118041 TBXAS1 final crispr E24 A549 96 829 Apoptosis +0.1586208112473136 1.4519181233577869e-18 BR00118044 AKR1B1 final crispr L21 A549 96 1649 Apoptosis +0.14554129596094795 1.6377806330772913e-18 BR00118041 GJB4 final crispr N01 A549 96 1954 Apoptosis +0.21309513277132494 3.1408190720685903e-18 BR00118041 TUBB4B final crispr C04 A549 96 890 Apoptosis +0.21386990828300084 3.1502644372241383e-18 BR00118041 SCNN1G final crispr G24 A549 96 888 Apoptosis +0.41379310344827586 3.63295368059707e-18 BR00118044 RPL23A final crispr M18 A549 96 232 Apoptosis +0.12998347251217815 3.997765075137752e-18 BR00118041 CACNG1 final crispr L02 A549 96 2400 Apoptosis +0.2266325224071703 5.4817734067004564e-18 BR00118043 OPRL1 final crispr A04 A549 96 781 Apoptosis +0.2545757071547421 1.6298278393660374e-17 BR00118041 SLC7A11 final crispr P05 A549 96 601 Apoptosis +0.22942571127502634 2.236474884576861e-17 BR00118043 ATP5F1D final crispr G21 A549 96 728 Apoptosis +0.21423358026301056 2.3543709755131283e-17 BR00118043 CDK7 final crispr E12 A549 96 841 Apoptosis +0.2608465207844325 2.7259518476964565e-17 BR00118044 OPRL1 final crispr A11 A549 96 564 Apoptosis +0.25414321787767274 3.248535574446292e-17 BR00118041 AKR1C1 final crispr B13 A549 96 589 Apoptosis +0.22706817221904516 5.01968633199731e-17 BR00118041 TGFBR1 final crispr B08 A549 96 729 Apoptosis +0.22345630739640907 6.413753206791991e-17 BR00118043 ALDH2 final crispr A10 A549 96 754 Apoptosis +0.2586218071281815 7.044331213281293e-17 BR00118043 GRIN2A final crispr A23 A549 96 557 Apoptosis +0.220495842315984 7.602096990650779e-17 BR00118043 TGM2 final crispr B09 A549 96 765 Apoptosis +0.22247139324938187 1.139483680742218e-16 BR00118041 HSD11B1 final crispr O23 A549 96 744 Apoptosis +0.14089020063625243 1.5006182698761757e-16 BR00118043 LPAR1 final crispr L01 A549 96 1855 Apoptosis +0.21114242615527323 1.7561350268852466e-16 BR00118043 AVPR1A final crispr J07 A549 96 822 Apoptosis +0.25082614942528736 1.79875576358906e-16 BR00118041 HSP90AB1 final crispr B04 A549 96 576 Apoptosis +0.6482594936708861 2.027443743001884e-16 BR00118042 RPL23A final crispr G14 A549 96 80 Apoptosis +0.24311183144246354 2.0754712034958252e-16 BR00118044 FOXM1 final crispr A19 A549 96 617 Apoptosis +0.2231146654303817 3.1817447593296413e-16 BR00118041 CATSPER4 final crispr P02 A549 96 720 Apoptosis +0.20872953737181488 3.6710710421541787e-16 BR00118043 PDPK1 final crispr E16 A549 96 823 Apoptosis +0.21868456375838927 3.742552144053983e-16 BR00118041 S1PR4 final crispr L05 A549 96 745 Apoptosis +0.3323506289308176 3.8727162318037393e-16 BR00118041 CDK4 final crispr B15 A549 96 318 Apoptosis +0.29468694568291864 4.458972304539409e-16 BR00118041 PPAT final crispr E13 A549 96 408 Apoptosis +0.25736424248205975 5.960699082056053e-16 BR00118041 HDAC3 final crispr K19 A549 96 531 Apoptosis +0.2745182012847966 6.298263684330838e-16 BR00118044 CDK4 final crispr B15 A549 96 467 Apoptosis +0.26282634730538923 9.209816373295648e-16 BR00118041 HTR3A final crispr O20 A549 96 501 Apoptosis +0.21251629726205998 1.41806509682704e-15 BR00118044 FFAR2 final crispr A06 A549 96 767 Apoptosis +0.23208722741433022 1.4351367765048584e-15 BR00118041 CYP2A6 final crispr C07 A549 96 642 Apoptosis +0.1887966804979253 1.9777766045466075e-15 BR00118043 NAMPT final crispr I09 A549 96 964 Apoptosis +0.22672672672672672 2.0606954117954263e-15 BR00118041 HRH4 final crispr H24 A549 96 666 Apoptosis +0.21436519832373238 2.1668401211013783e-15 BR00118041 IMPDH1 final crispr F15 A549 96 739 Apoptosis +0.22893245068386311 2.3360636723420788e-15 BR00118041 CSF1R final crispr J15 A549 96 648 Apoptosis +0.11394043445010107 2.468122399416814e-15 BR00118041 PTK2B final crispr N15 A549 96 2637 Apoptosis +0.20577753441802252 2.5202924065916816e-15 BR00118041 PTGIS final crispr I16 A549 96 800 Apoptosis +0.44860092772706867 2.9746204527846286e-15 BR00118041 RPL3 final crispr K04 A549 96 164 Apoptosis +0.2130257801899593 4.722903726031153e-15 BR00118043 S1PR1 final crispr A18 A549 96 737 Apoptosis +0.24429053523779626 4.958959706185656e-15 BR00118041 PDE3A final crispr P18 A549 96 554 Apoptosis +0.1869384586472894 5.842147179400283e-15 BR00118043 KCNQ2 final crispr A16 A549 96 947 Apoptosis +0.19352455108851105 9.109523914582153e-15 BR00118043 HRH4 final crispr A08 A549 96 870 Apoptosis +0.1150328820956101 1.1050848969369353e-14 BR00118041 AKR1B1 final crispr L21 A549 96 2467 Apoptosis +0.21124209457334378 1.1810836931272109e-14 BR00118043 GHSR final crispr A09 A549 96 726 Apoptosis +0.5489762568489859 1.207786636892263e-14 BR00118041 RPL23A final crispr M18 A549 96 103 Apoptosis +0.22555205047318613 1.5254452747529997e-14 BR00118041 CHEK2 final crispr M07 A549 96 634 Apoptosis +0.22896343110246853 1.742917150367103e-14 BR00118043 FOXM1 final crispr A19 A549 96 612 Apoptosis +0.20404744377403664 2.113821343831296e-14 BR00118041 CDC25A final crispr C14 A549 96 764 Apoptosis +0.1944530191559054 2.1960509186201013e-14 BR00118043 MMP2 final crispr E07 A549 96 836 Apoptosis 0.15877041871241138 2.5641805663416976e-31 BR00118041 MAPK8 final crispr D07 A549 96 2807 Binuclear 0.14899989746990452 1.4179297118801799e-30 BR00118041 UGT1A9 final crispr J01 A549 96 3112 Binuclear 0.15699000497713952 6.501780847624943e-30 BR00118041 LYN final crispr N13 A549 96 2739 Binuclear @@ -639,6 +6309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.1484932944912474 3.1256561349216684e-19 BR00118041 GJB4 final crispr N01 A549 96 1954 Binuclear 0.14734640264276042 4.592867918981159e-18 BR00118043 LPAR1 final crispr L01 A549 96 1855 Binuclear 0.14507225722796357 3.217667260400884e-17 BR00118043 GJB4 final crispr N01 A549 96 1829 Binuclear +0.12078379413452377 3.7654770864855544e-16 BR00118041 AKR1B1 final crispr L21 A549 96 2467 Binuclear +0.13130304543185223 1.836752617458024e-15 BR00118041 EZH2 final crispr H09 A549 96 2003 Binuclear +0.13448069785485123 4.158307717238652e-15 BR00118043 UGT1A9 final crispr J01 A549 96 1854 Binuclear +0.13719268379587474 9.984351924729923e-15 BR00118044 GJB4 final crispr N01 A549 96 1740 Binuclear +0.11481297842727906 3.191995301386722e-14 BR00118041 CACNG1 final crispr L02 A549 96 2400 Binuclear +0.1286548477878549 1.1024951721364956e-13 BR00118043 PTK2B final crispr N15 A549 96 1837 Binuclear +0.10384443247071476 3.6401796429558624e-13 BR00118041 AGER final crispr J18 A549 96 2707 Binuclear +0.11521123024577068 8.93458209789613e-13 BR00118041 GRIN2A final crispr P09 A549 96 2132 Binuclear +0.09893348458746841 1.4582273250294948e-12 BR00118041 FOXM1 final crispr F23 A549 96 2840 Binuclear +0.1070578231292517 3.2876435353281488e-12 BR00118041 TUBB final crispr J17 A549 96 2352 Binuclear +0.10192737984324815 1.5777786598788686e-11 BR00118041 PORCN final crispr L13 A549 96 2443 Binuclear +0.1146435872023638 1.8778877890297576e-11 BR00118043 S1PR2 final crispr J23 A549 96 1919 Binuclear +0.1111484496018167 2.2774591187443343e-11 BR00118041 LPAR1 final crispr L01 A549 96 2026 Binuclear +0.11796715140344574 4.541224739304721e-11 BR00118043 HSD11B1 final crispr O01 A549 96 1752 Binuclear +0.11453608035538644 5.634654368742449e-11 BR00118044 TNF final crispr N17 A549 96 1845 Binuclear +0.10698418460352158 5.64716813844565e-11 BR00118041 CDK2 final crispr L19 A549 96 2107 Binuclear +0.09985935250996755 1.2720461381706583e-10 BR00118041 CACNG1 final crispr N23 A549 96 2338 Binuclear +0.1186369581770278 1.4634090055857972e-10 BR00118044 AKR1B1 final crispr L21 A549 96 1649 Binuclear +0.10299342793800322 2.532989554470601e-10 BR00118041 AKR1B1 final crispr H17 A549 96 2137 Binuclear +0.1101809466268232 4.798048185138626e-10 BR00118044 AKR1B1 final crispr H17 A549 96 1818 Binuclear +0.15376106194690264 9.709890527312539e-10 BR00118043 PIK3CG final crispr E22 A549 96 904 Binuclear +0.10824353429778542 1.412954936941382e-09 BR00118044 SLC29A1 final crispr N21 A549 96 1789 Binuclear +0.15928540930552032 2.1915259710446843e-09 BR00118043 TGFBR1 final crispr B08 A549 96 802 Binuclear +0.15527225119653168 3.0135307204143926e-09 BR00118043 CYP2A6 final crispr C07 A549 96 835 Binuclear +0.15176470588235294 5.897670591956234e-09 BR00118043 FGF1 final crispr I19 A549 96 850 Binuclear +0.2641188493669323 7.648976446387192e-09 BR00118043 RPL3 final crispr K04 A549 96 269 Binuclear +0.10486541508518107 8.355261373412089e-09 BR00118044 LYN final crispr N13 A549 96 1748 Binuclear +0.10853995978157496 2.344904242958436e-08 BR00118044 UGT1A9 final crispr J01 A549 96 1538 Binuclear +0.10101279206348951 2.5899714968116378e-08 BR00118044 GAA final crispr L17 A549 96 1765 Binuclear +0.08218819610964084 3.175244651451375e-08 BR00118041 PTK2B final crispr N15 A549 96 2637 Binuclear +0.10767478527612627 3.8545466591020794e-08 BR00118044 ELANE final crispr N19 A549 96 1526 Binuclear +0.0997611412433852 5.451107514420381e-08 BR00118044 LPAR1 final crispr L01 A549 96 1740 Binuclear +0.15081521739130435 1.0183735755500644e-07 BR00118043 PPAT final crispr E13 A549 96 736 Binuclear +0.09957498482088646 1.5822260312124407e-07 BR00118041 P2RY12 final crispr P19 A549 96 1647 Binuclear +0.48412698412698413 2.2853747773825884e-07 BR00118041 HSD11B1 final crispr O01 A549 96 63 Binuclear +0.14680490742134578 2.4780998070208536e-07 BR00118043 SLC7A11 final crispr P05 A549 96 728 Binuclear +0.1870645694175106 2.7486747255774686e-07 BR00118044 RPL3 final crispr K04 A549 96 441 Binuclear +0.12858874865210662 2.827401033428852e-07 BR00118041 ITGB2 final crispr A17 A549 96 945 Binuclear +0.12366114897760468 2.926203066455252e-07 BR00118043 CTSG final crispr G18 A549 96 1027 Binuclear +0.09540528944608867 3.7400488150257335e-07 BR00118043 CACNG1 final crispr N23 A549 96 1684 Binuclear +0.13359004193600046 4.986088617851019e-07 BR00118043 CDK7 final crispr E12 A549 96 841 Binuclear +0.16742687336651033 5.954790454856183e-07 BR00118043 CDK4 final crispr B15 A549 96 527 Binuclear +0.09075816270060874 6.756719630667092e-07 BR00118044 HSD11B1 final crispr O01 A549 96 1807 Binuclear +0.09075816270060874 6.756719630667092e-07 BR00118044 PORCN final crispr L13 A549 96 1807 Binuclear +0.09311373932288965 7.503454912104999e-07 BR00118044 AKT1 final crispr J19 A549 96 1700 Binuclear +0.1310644646807635 9.024469984643158e-07 BR00118043 MMP2 final crispr E07 A549 96 836 Binuclear +0.1696685161473894 9.622229368568554e-07 BR00118043 DHH final crispr F05 A549 96 497 Binuclear +0.1399700235102395 1.0044680195299925e-06 BR00118041 TGFBR1 final crispr B08 A549 96 729 Binuclear +0.09874363290317613 1.0218880790926126e-06 BR00118044 KCNQ2 final crispr P13 A549 96 1476 Binuclear +0.14714714714714713 1.0477884131623173e-06 BR00118041 HRH4 final crispr H24 A549 96 666 Binuclear +0.11541072044001491 1.1807587631699813e-06 BR00118043 MAPK8 final crispr D13 A549 96 1069 Binuclear +0.1333145451997911 1.1926204623747764e-06 BR00118043 MME final crispr H08 A549 96 792 Binuclear +0.08874187508487216 1.29127867031252e-06 BR00118041 KRAS final crispr F07 A549 96 1797 Binuclear +0.11768574872397732 1.536523822379634e-06 BR00118041 BRD4 final crispr M19 A549 96 1003 Binuclear +0.15793956547946641 1.83190093776089e-06 BR00118041 PDPK1 final crispr E16 A549 96 553 Binuclear +0.08122446928417078 2.0828535361273133e-06 BR00118043 AGER final crispr J18 A549 96 2077 Binuclear +0.11182401466544455 2.325283915920661e-06 BR00118043 PRKCE final crispr I17 A549 96 1091 Binuclear +0.1321853539131026 2.583492842307328e-06 BR00118041 TUBB3 final crispr F19 A549 96 770 Binuclear +0.09522821197381413 2.757743505581351e-06 BR00118044 S1PR2 final crispr J23 A549 96 1478 Binuclear +0.127559817251581 2.762463090941603e-06 BR00118043 PDPK1 final crispr E16 A549 96 823 Binuclear +0.13482613277133826 2.8592221737974446e-06 BR00118043 ATP5F1D final crispr G21 A549 96 728 Binuclear +0.0800539794822414 3.0196541889432033e-06 BR00118041 AKT1 final crispr J19 A549 96 2080 Binuclear +0.14819483766971833 4.474193080483821e-06 BR00118041 CDK7 final crispr E12 A549 96 581 Binuclear +0.0850253807106599 4.844285095748313e-06 BR00118041 TNF final crispr N17 A549 96 1773 Binuclear +0.14791796336298954 5.537221581099244e-06 BR00118042 SLC29A1 final crispr E03 A549 96 573 Binuclear +0.15865868263473054 6.005217295534455e-06 BR00118041 HTR3A final crispr O20 A549 96 501 Binuclear +0.1165341173484496 6.338258710044892e-06 BR00118043 RNASE1 final crispr I13 A549 96 921 Binuclear +0.11558854718981973 6.606291551495163e-06 BR00118043 HIF1A final crispr M24 A549 96 943 Binuclear +0.14866581545022653 7.735138813959547e-06 BR00118043 GRIN2A final crispr A23 A549 96 557 Binuclear +0.08730360233083749 8.949994791850497e-06 BR00118044 OPRM1 final crispr P22 A549 96 1604 Binuclear +0.08996403598143456 8.971852053718123e-06 BR00118044 JAK1 final crispr J09 A549 96 1515 Binuclear +0.11043017506889286 9.544223159797845e-06 BR00118043 ELANE final crispr H10 A549 96 992 Binuclear +0.12112105882387807 1.0174516875520694e-05 BR00118043 AVPR1A final crispr J07 A549 96 822 Binuclear +0.1544278881168435 1.0444809577726697e-05 BR00118041 COMT final crispr A12 A549 96 505 Binuclear +0.1048141377209019 1.0487326682276006e-05 BR00118044 USP1 final crispr K18 A549 96 1098 Binuclear +0.11203319502074689 1.0912913145386982e-05 BR00118043 NAMPT final crispr I09 A549 96 964 Binuclear +0.11711420811208734 1.124771437784282e-05 BR00118043 BAX final crispr E06 A549 96 868 Binuclear +0.10269487294135181 1.1373373012733898e-05 BR00118044 RNASE1 final crispr K09 A549 96 1134 Binuclear +0.12649800266311584 1.1788834828892875e-05 BR00118043 KCNMA1 final crispr A07 A549 96 751 Binuclear +0.1702700046679606 1.2173833766871098e-05 BR00118042 ELANE final crispr H10 A549 96 404 Binuclear +0.1251638155480613 1.2195871446096527e-05 BR00118041 KCNMA1 final crispr A07 A549 96 758 Binuclear +0.13722397476340695 1.270402658404831e-05 BR00118041 CHEK2 final crispr M07 A549 96 634 Binuclear +0.12172090112640802 1.3344623184114133e-05 BR00118041 PTGIS final crispr I16 A549 96 800 Binuclear +0.08806262230919765 1.3581135873709793e-05 BR00118043 CACNG1 final crispr L02 A549 96 1533 Binuclear +0.14660482248218001 1.4876883213905243e-05 BR00118043 CDC25A final crispr D06 A549 96 545 Binuclear +0.12213740458015267 1.582595724788617e-05 BR00118043 HTR3A final crispr O20 A549 96 786 Binuclear +0.10685757466657698 1.8364203992730638e-05 BR00118041 MMP2 final crispr D14 A549 96 1004 Binuclear +0.13167198393004845 2.0090913565404806e-05 BR00118041 COMT final crispr M02 A549 96 650 Binuclear +0.07135855285933451 2.1803911693800686e-05 BR00118041 HCK final crispr H23 A549 96 2222 Binuclear +0.11677916448826878 2.1831915824092762e-05 BR00118041 TBXAS1 final crispr E24 A549 96 829 Binuclear 0.2566045869063645 6.61891902854213e-16 BR00118044 AURKB final crispr C13 A549 96 533 Elongated 0.43286099865047234 1.7457203128476372e-13 BR00118042 AURKB final crispr C13 A549 96 152 Elongated 0.12728278915329275 3.597766963900009e-13 BR00118044 HSD11B1 final crispr O01 A549 96 1807 Elongated @@ -649,6 +6409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.0979328188535047 4.388243393645154e-08 BR00118043 GJB4 final crispr N01 A549 96 1829 Elongated 0.13060474137598618 4.820914603666616e-08 BR00118044 HIF1A final crispr A01 A549 96 1021 Elongated 0.22739141546017178 2.4198527928963194e-07 BR00118044 PLK1 final crispr G09 A549 96 301 Elongated +0.1364723176384118 4.2381434391033274e-07 BR00118044 ITGB2 final crispr A17 A549 96 818 Elongated +0.14158490474279947 1.3350593443243423e-06 BR00118044 FFAR2 final crispr A24 A549 96 703 Elongated +0.3939393939393939 1.4856649390983498e-06 BR00118042 PLK1 final crispr G09 A549 96 87 Elongated +0.08932746026043538 1.5402314183669155e-06 BR00118043 HSD11B1 final crispr O01 A549 96 1752 Elongated +0.08661207948645963 1.670489343363048e-06 BR00118043 LPAR1 final crispr L01 A549 96 1855 Elongated +0.07696907256164569 2.258353158210785e-06 BR00118044 PTK2B final crispr N15 A549 96 2302 Elongated +0.12144712932735613 4.3819671960885714e-06 BR00118043 IGF1R final crispr E19 A549 96 877 Elongated +0.11276750994206707 1.016401445864828e-05 BR00118044 SSTR2 final crispr P10 A549 96 953 Elongated +0.110680492103417 1.2583754286630136e-05 BR00118043 CATSPER4 final crispr A02 A549 96 968 Elongated +0.07958788131522097 1.6763184662511402e-05 BR00118043 PTK2B final crispr N15 A549 96 1837 Elongated +0.2140309728826629 1.6798188816717965e-05 BR00118043 PLK1 final crispr G09 A549 96 251 Elongated +0.08404477449207134 1.7110292310071677e-05 BR00118041 NTRK1 final crispr P07 A549 96 1637 Elongated +0.08378870673952642 1.8836009367282497e-05 BR00118041 P2RY12 final crispr P19 A549 96 1647 Elongated +0.06356305746846838 2.204247329856308e-05 BR00118041 MAPK8 final crispr D07 A549 96 2807 Elongated +0.13832117981753375 2.586023128884824e-05 BR00118043 AURKB final crispr C13 A549 96 577 Elongated +0.10117464092476074 2.7432817357860398e-05 BR00118044 CACNB4 final crispr B01 A549 96 1081 Elongated +0.06546385197952505 2.832902003978166e-05 BR00118041 RGS4 final crispr N11 A549 96 2591 Elongated +0.10629818234001828 3.00726310279265e-05 BR00118044 SCNN1G final crispr G24 A549 96 974 Elongated +0.1261646189391854 3.0245626718460405e-05 BR00118042 GLRA3 final crispr F16 A549 96 693 Elongated +0.0984071567132561 3.0889501836341195e-05 BR00118044 P2RY12 final crispr P19 A549 96 1129 Elongated +0.08704117092478748 3.587109583510323e-05 BR00118043 BTK final crispr P17 A549 96 1434 Elongated +0.08505034218453152 4.8931956033175073e-05 BR00118044 S1PR1 final crispr P23 A549 96 1461 Elongated +0.14586576898800757 5.3031748813962525e-05 BR00118043 FFAR2 final crispr A24 A549 96 490 Elongated +0.10375611873224812 6.207984635114379e-05 BR00118043 CHRM2 final crispr O22 A549 96 955 Elongated +0.08697038201126676 7.283152360890627e-05 BR00118044 AVPR1A final crispr D05 A549 96 1335 Elongated +0.11771080821974907 7.401907164783431e-05 BR00118043 GHSR final crispr A09 A549 96 726 Elongated +0.09818875119161107 8.013759226969124e-05 BR00118044 GHSR final crispr B20 A549 96 1049 Elongated +0.11473272490221642 8.116889336776942e-05 BR00118044 FFAR2 final crispr A06 A549 96 767 Elongated +0.13373280013481195 8.413137230188287e-05 BR00118043 GRIN2A final crispr A23 A549 96 557 Elongated +0.08639695179573538 8.598563977097422e-05 BR00118043 TGFBR1 final crispr P24 A549 96 1336 Elongated +0.19670649509803922 8.827114026206235e-05 BR00118041 AURKB final crispr C13 A549 96 255 Elongated +0.11527503112868967 9.315355473524553e-05 BR00118044 CCND1 final crispr B23 A549 96 738 Elongated +0.10451045104510451 9.630312902239631e-05 BR00118044 ALDH2 final crispr A10 A549 96 909 Elongated +0.11538294624544561 0.00010899969035755672 BR00118044 KCNN4 final crispr K01 A549 96 729 Elongated +0.09217391304347826 0.00011313769997149363 BR00118043 SSTR2 final crispr C02 A549 96 1150 Elongated +0.09244137957566315 0.00012652148248201345 BR00118044 GHSR final crispr A09 A549 96 1118 Elongated +0.09411532580279189 0.00014465767871350943 BR00118043 ERBB2 final crispr I11 A549 96 1067 Elongated +0.0730973778323238 0.00016582258725081136 BR00118044 LPAR1 final crispr L01 A549 96 1740 Elongated +0.07603376007202481 0.00017428135605397518 BR00118044 OPRM1 final crispr P22 A549 96 1604 Elongated +0.10981912144702842 0.0001743809878609951 BR00118043 KRAS final crispr F07 A549 96 774 Elongated +0.10159553795032958 0.0001954621989836703 BR00118043 PLD1 final crispr F04 A549 96 881 Elongated +0.0986040191072311 0.00019837179526800412 BR00118044 MAPK14 final crispr A20 A549 96 934 Elongated +0.07085119594275537 0.00023326721540049944 BR00118044 GUCY1B1 final crispr H21 A549 96 1796 Elongated +0.2770679770679771 0.0002607167721173943 BR00118042 CACNG1 final crispr L02 A549 96 111 Elongated +0.08895748266251863 0.00028135118115979344 BR00118044 GLRA3 final crispr E21 A549 96 1112 Elongated +0.08638382744800614 0.00028274744825102936 BR00118044 CSF1R final crispr C08 A549 96 1177 Elongated +0.09376025721930405 0.0002952007567315727 BR00118043 PPARD final crispr E05 A549 96 991 Elongated +0.07243671715817891 0.00030549339123857506 BR00118044 CACNG1 final crispr N23 A549 96 1653 Elongated +0.08395604395604396 0.00032799904160781343 BR00118043 P2RY12 final crispr O21 A549 96 1222 Elongated +0.08494533221194281 0.0003733257516505138 BR00118043 HSP90AA1 final crispr C03 A549 96 1189 Elongated +0.18210622078614674 0.00037606306638483426 BR00118042 OPRL1 final crispr A11 A549 96 254 Elongated +0.10120481927710843 0.00040263342268277236 BR00118044 CDK4 final crispr P03 A549 96 830 Elongated +0.06730354775501456 0.00042776093168842087 BR00118043 UGT1A9 final crispr J01 A549 96 1854 Elongated +0.09759686888454011 0.00044164573266426357 BR00118043 ITGB2 final crispr A17 A549 96 876 Elongated +0.08062575430417684 0.0004618061517959743 BR00118043 PRKCB final crispr M03 A549 96 1282 Elongated +0.21523809523809523 0.00046652418813553006 BR00118042 AGER final crispr J18 A549 96 177 Elongated +0.07407412245182302 0.00046921305542937296 BR00118044 HCK final crispr H23 A549 96 1515 Elongated +0.0679070777775593 0.0004867509999148917 BR00118044 SLC29A1 final crispr N21 A549 96 1789 Elongated +0.08841577189182644 0.0004882499884745331 BR00118043 CHRM3 final crispr B21 A549 96 1051 Elongated +0.07063069628308404 0.0004960746756243096 BR00118044 AKR1B1 final crispr L21 A549 96 1649 Elongated +0.09928229665071771 0.0005230027861367337 BR00118044 PDPK1 final crispr E16 A549 96 836 Elongated +0.08560233457931668 0.0005492789802804555 BR00118041 KCNQ2 final crispr A16 A549 96 1105 Elongated +0.27124887690925426 0.0005505280772065067 BR00118042 TUBB final crispr J17 A549 96 105 Elongated +0.310126582278481 0.0005570410338568202 BR00118042 PLK1 final crispr F13 A549 96 80 Elongated +0.08429517353919538 0.0005919135918255761 BR00118044 KCNQ2 final crispr A16 A549 96 1128 Elongated +0.11900532859680284 0.0006809580186752918 BR00118042 PPAT final crispr G13 A549 96 563 Elongated +0.09491525423728814 0.0006842237829222153 BR00118043 HIF1A final crispr A01 A549 96 885 Elongated +0.09913258983890955 0.0007133311362601822 BR00118044 OPRL1 final crispr A04 A549 96 807 Elongated +0.10161377659592814 0.0007230400041285641 BR00118044 GRIN2A final crispr P09 A549 96 762 Elongated +0.10252996005326231 0.0007389585009410143 BR00118043 KCNMA1 final crispr A07 A549 96 751 Elongated +0.08759065989532373 0.000764783016624455 BR00118043 ABL1 final crispr C01 A549 96 1016 Elongated +0.07478632478632478 0.0007739915828649193 BR00118044 PAK1 final crispr K10 A549 96 1404 Elongated +0.10323827695467101 0.0007834093960087373 BR00118044 GRIN2A final crispr A23 A549 96 722 Elongated +0.08029717373233583 0.0007951796547488476 BR00118043 CCR1 final crispr G02 A549 96 1203 Elongated +0.08819196790403631 0.000802822480030972 BR00118043 CACNA2D3 final crispr N24 A549 96 992 Elongated +0.09670717865282087 0.0008522246742283288 BR00118043 AVPR1A final crispr J07 A549 96 822 Elongated +0.09397302713301922 0.0008962372705191043 BR00118044 GJB4 final crispr H01 A549 96 861 Elongated +0.11150373822340069 0.0009015136999960973 BR00118044 CA5A final crispr M01 A549 96 614 Elongated +0.08049763877751047 0.0010242376773987717 BR00118044 VEGFA final crispr C24 A549 96 1161 Elongated +0.07177033492822966 0.001063022162760541 BR00118043 TUBB final crispr J17 A549 96 1463 Elongated +0.10894638844301766 0.0010865751734342886 BR00118043 ADA final crispr O24 A549 96 625 Elongated +0.08583106402186476 0.0011068657589433603 BR00118044 HSP90AA1 final crispr C03 A549 96 1003 Elongated +0.16649317603516076 0.001174801704907703 BR00118042 TUBB3 final crispr K11 A549 96 262 Elongated +0.0988037240956598 0.001178230548123135 BR00118043 ALDH2 final crispr A10 A549 96 754 Elongated +0.1741176062084411 0.001182962701089118 BR00118042 BRAF final crispr J10 A549 96 239 Elongated +0.17672413793103448 0.001252551133825485 BR00118042 SIRT2 final crispr P01 A549 96 230 Elongated +0.09962136927521931 0.0012679423271480532 BR00118041 TGFBR1 final crispr B08 A549 96 729 Elongated +0.08936945134515763 0.0012760950276819772 BR00118043 KCNN4 final crispr K01 A549 96 912 Elongated +0.10106885259076206 0.0014026774663150813 BR00118042 PTGIS final crispr I16 A549 96 706 Elongated +0.0889132821075741 0.0014819728685358817 BR00118041 KRAS final crispr D21 A549 96 911 Elongated 0.20935422613469593 4.1539162903169025e-53 BR00118041 LYN final crispr N13 A549 96 2739 Grape 0.19481074052903646 4.254881860866628e-47 BR00118041 MAPK8 final crispr D07 A549 96 2807 Grape 0.20738937200108798 7.582283760586183e-44 BR00118044 PTK2B final crispr N15 A549 96 2302 Grape @@ -659,6 +6509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.16172929714683368 7.34508995125649e-28 BR00118041 CACNG1 final crispr L02 A549 96 2400 Grape 0.1501522264355371 6.634486003934192e-26 BR00118041 RGS4 final crispr N11 A549 96 2591 Grape 0.1446557850237058 3.946079656571959e-25 BR00118041 AGER final crispr J18 A549 96 2707 Grape +0.17422843120284293 4.577052721655611e-25 BR00118043 LPAR1 final crispr L01 A549 96 1855 Grape +0.1632966460627227 5.967640359672206e-25 BR00118041 CDK2 final crispr L19 A549 96 2107 Grape +0.17740739274450032 2.2568764370903426e-24 BR00118044 GJB4 final crispr N01 A549 96 1740 Grape +0.1768524750254035 3.1599527628696107e-24 BR00118044 LPAR1 final crispr L01 A549 96 1740 Grape +0.150574114996317 1.0101863648788159e-23 BR00118041 TUBB final crispr J17 A549 96 2352 Grape +0.4658417405198521 2.2026456242114054e-23 BR00118043 RPL23A final crispr M18 A549 96 233 Grape +0.43287287891466275 3.633218383527307e-23 BR00118043 RPL3 final crispr K04 A549 96 269 Grape +0.1680356251885978 5.598184444329725e-23 BR00118043 GJB4 final crispr N01 A549 96 1829 Grape +0.33260869565217394 6.293928791257843e-23 BR00118041 OPRL1 final crispr A11 A549 96 460 Grape +0.25014077708953425 1.280072858948355e-22 BR00118043 TGFBR1 final crispr B08 A549 96 802 Grape +0.3344414688952504 1.6082379500241953e-22 BR00118044 RPL3 final crispr K04 A549 96 441 Grape +0.16353688694872787 1.1830211519157898e-21 BR00118044 AKR1B1 final crispr H17 A549 96 1818 Grape +0.28354732332909194 3.871500883971218e-21 BR00118041 CDK7 final crispr E12 A549 96 581 Grape +0.34568274610615457 4.0055481986578846e-21 BR00118041 CA5A final crispr M01 A549 96 389 Grape +0.2728119085895688 4.4463933070472965e-21 BR00118041 CDK7 final crispr I14 A549 96 626 Grape +0.16781126457714035 9.955371734212583e-21 BR00118044 AKR1B1 final crispr L21 A549 96 1649 Grape +0.15938018815716656 1.934567390291076e-20 BR00118044 HSD11B1 final crispr O01 A549 96 1807 Grape +0.15915363414176653 3.1573791585742933e-20 BR00118044 SLC29A1 final crispr N21 A549 96 1789 Grape +0.16313587163260365 3.5211335440009387e-20 BR00118044 AKT1 final crispr J19 A549 96 1700 Grape +0.3072033898305085 4.578518121986606e-20 BR00118043 TUBB3 final crispr K11 A549 96 472 Grape +0.1571665744327615 6.934068350961398e-20 BR00118044 PORCN final crispr L13 A549 96 1807 Grape +0.15930711632537978 7.044096219836489e-20 BR00118044 LYN final crispr N13 A549 96 1748 Grape +0.2623565754633716 4.026083452101252e-19 BR00118041 BTK final crispr D24 A549 96 618 Grape +0.15262678718139938 4.128911961131197e-19 BR00118043 PTK2B final crispr N15 A549 96 1837 Grape +0.13157082580978 4.750104040012511e-19 BR00118041 AKR1B1 final crispr L21 A549 96 2467 Grape +0.14694328530561898 7.715694431218431e-19 BR00118041 GJB4 final crispr N01 A549 96 1954 Grape +0.3085727969348659 8.196904490839057e-19 BR00118041 AVPR1A final crispr J07 A549 96 432 Grape +0.14735242890292766 1.2260594189381112e-18 BR00118043 S1PR2 final crispr J23 A549 96 1919 Grape +0.1503289908305367 1.2700054193060435e-18 BR00118044 TNF final crispr N17 A549 96 1845 Grape +0.1253388656696492 1.7525694657835142e-18 BR00118041 PTK2B final crispr N15 A549 96 2637 Grape +0.1480151490793358 3.285940276226968e-18 BR00118043 UGT1A9 final crispr J01 A549 96 1854 Grape +0.26583969524801393 3.723139961247743e-18 BR00118041 TGFBR1 final crispr P24 A549 96 569 Grape +0.2741059974199266 5.290469773747616e-18 BR00118041 MMP2 final crispr E07 A549 96 527 Grape +0.354640088593577 1.99050169213328e-17 BR00118043 RPL23A final crispr G14 A549 96 301 Grape +0.23240910562088682 2.2181909956369492e-17 BR00118041 HRH4 final crispr A08 A549 96 715 Grape +0.35081967213114756 4.732129802538838e-17 BR00118041 FFAR2 final crispr A24 A549 96 305 Grape +0.25125628140703515 5.896320295082901e-17 BR00118041 HIF1A final crispr M24 A549 96 597 Grape +0.264426622748917 8.296582112138757e-17 BR00118043 CDK4 final crispr B15 A549 96 527 Grape +0.22251994580761705 2.270450950450741e-16 BR00118043 SLC7A11 final crispr P05 A549 96 728 Grape +0.2596078763916713 2.545351607347199e-16 BR00118041 HDAC3 final crispr K19 A549 96 531 Grape +0.23059324811537202 2.804128415163424e-16 BR00118043 FFAR2 final crispr A06 A549 96 678 Grape +0.1534705057850905 2.849104350479311e-16 BR00118044 UGT1A9 final crispr J01 A549 96 1538 Grape +0.27771578728728 5.430259787040672e-16 BR00118041 ASIC1 final crispr M20 A549 96 453 Grape +0.1995912390946251 5.815864452587623e-16 BR00118041 SCNN1G final crispr G24 A549 96 888 Grape +0.2173538036915646 5.968130449311997e-16 BR00118041 HSD11B1 final crispr O23 A549 96 744 Grape +0.12033898446962943 6.647594763474486e-16 BR00118041 PORCN final crispr L13 A549 96 2443 Grape +0.25398519832202177 7.463860548771499e-16 BR00118043 CDC25A final crispr D06 A549 96 545 Grape +0.25761267413275063 8.849435264885001e-16 BR00118041 ABL1 final crispr P20 A549 96 523 Grape +0.25345124959629484 9.562410871599486e-16 BR00118043 CDK2 final crispr F08 A549 96 542 Grape +0.2527111632847001 1.4027333109750364e-15 BR00118041 RNASE1 final crispr I13 A549 96 534 Grape +0.24660539636655887 2.4036643102844073e-15 BR00118043 GRIN2A final crispr A23 A549 96 557 Grape +0.23745256378214244 3.880974330701078e-15 BR00118041 AKR1C1 final crispr B13 A549 96 589 Grape +0.2721238938053097 3.94827778022072e-15 BR00118042 TGFBR1 final crispr B08 A549 96 452 Grape +0.1293060409385921 5.239006849640045e-15 BR00118041 EZH2 final crispr H09 A549 96 2003 Grape +0.18822945798526805 5.6372852847764485e-15 BR00118041 PIK3CG final crispr E22 A549 96 937 Grape +0.21141835144257184 8.084925787186531e-15 BR00118041 TGFBR1 final crispr B08 A549 96 729 Grape +0.3723013493253373 8.867397683535059e-15 BR00118042 SIRT2 final crispr P01 A549 96 230 Grape +0.23294509151414308 1.044322465570388e-14 BR00118041 SLC7A11 final crispr P05 A549 96 601 Grape +0.2092657314001497 1.0468214279584327e-14 BR00118041 IMPDH1 final crispr F15 A549 96 739 Grape +0.20772303595206393 1.3626517184924128e-14 BR00118043 KCNMA1 final crispr A07 A549 96 751 Grape +0.2849248395010178 1.4098402482676714e-14 BR00118044 RPL23A final crispr G14 A549 96 391 Grape +0.18884154804557632 1.833073686292115e-14 BR00118041 HDAC3 final crispr G07 A549 96 897 Grape +0.19634788551801086 1.944245809013056e-14 BR00118041 TBXAS1 final crispr E24 A549 96 829 Grape +0.13389262122412382 2.7721059432670254e-14 BR00118044 GAA final crispr L17 A549 96 1765 Grape +0.21771771771771772 3.0965363222166046e-14 BR00118041 HRH4 final crispr H24 A549 96 666 Grape +0.2483869062850619 3.2042716248982284e-14 BR00118041 COMT final crispr A12 A549 96 505 Grape +0.14607284435496587 3.434766326666319e-14 BR00118044 KCNQ2 final crispr P13 A549 96 1476 Grape +0.13230778367874566 3.657237423561707e-14 BR00118041 KRAS final crispr F07 A549 96 1797 Grape +0.20351309175323462 4.301557269676785e-14 BR00118043 ALDH2 final crispr A10 A549 96 754 Grape +0.33955223880597013 4.341803340987066e-14 BR00118042 CDK7 final crispr I14 A549 96 268 Grape +0.24512280222697552 4.647017259510886e-14 BR00118043 OPRL1 final crispr A11 A549 96 511 Grape +0.43079455334430644 4.6628781008297597e-14 BR00118041 RPL3 final crispr K04 A549 96 164 Grape +0.19698842302878597 4.751628251313576e-14 BR00118041 PTGIS final crispr I16 A549 96 800 Grape +0.22082018927444794 5.948974448270696e-14 BR00118041 CHEK2 final crispr M07 A549 96 634 Grape +0.17510435240719727 8.495830320002878e-14 BR00118043 ELANE final crispr H10 A549 96 992 Grape +0.210618333397927 9.218429748876187e-14 BR00118041 HBB final crispr M08 A549 96 681 Grape +0.20313487881981032 1.1013130539259385e-13 BR00118043 ATP5F1D final crispr G21 A549 96 728 Grape +0.2125748502994012 1.2619818219344093e-13 BR00118041 VEGFA final crispr H02 A549 96 668 Grape +0.33863357843137254 1.5457567402287194e-13 BR00118041 AURKB final crispr C13 A549 96 255 Grape +0.18266579037170916 1.9428570920205798e-13 BR00118041 TUBB4B final crispr C04 A549 96 890 Grape +0.20217895224849328 2.490510702732126e-13 BR00118041 CATSPER4 final crispr P02 A549 96 720 Grape +0.1346197280066542 3.790388971290403e-13 BR00118044 OPRM1 final crispr P22 A549 96 1604 Grape +0.2988993710691824 3.8019077552546397e-13 BR00118041 CDK4 final crispr B15 A549 96 318 Grape +0.19617002237136466 4.455730840612904e-13 BR00118041 S1PR4 final crispr L05 A549 96 745 Grape +0.2386546906187625 5.854840537946207e-13 BR00118041 HTR3A final crispr O20 A549 96 501 Grape +0.19078104993597952 7.720702214365079e-13 BR00118043 OPRL1 final crispr A04 A549 96 781 Grape +0.18765231774543006 7.971667199470284e-13 BR00118043 KCNJ1 final crispr E14 A549 96 797 Grape +0.2761775009731413 8.306321199644539e-13 BR00118041 TUBB3 final crispr K11 A549 96 367 Grape +0.12698177160619173 8.939034364672979e-13 BR00118043 HSD11B1 final crispr O01 A549 96 1752 Grape +0.12944746607744823 9.284337316145302e-13 BR00118044 MET final crispr H13 A549 96 1680 Grape 0.38005745116121303 6.755083494278462e-35 BR00118044 AURKB final crispr C13 A549 96 533 Hole 0.17169781567728112 4.5391492673851525e-30 BR00118044 PTK2B final crispr N15 A549 96 2302 Hole 0.1779710310996887 5.138561416929755e-27 BR00118043 ELANE final crispr N19 A549 96 1915 Hole @@ -669,6 +6609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.15776546861015778 1.8165922732654436e-18 BR00118044 CACNG1 final crispr N23 A549 96 1653 Hole 0.1151633122512715 2.070628568133352e-18 BR00118041 UGT1A9 final crispr J01 A549 96 3112 Hole 0.12604032826587683 2.122048828011018e-18 BR00118041 RGS4 final crispr N11 A549 96 2591 Hole +0.15616057159249647 5.179222136761194e-18 BR00118044 AKR1B1 final crispr L21 A549 96 1649 Hole +0.14642824413823 8.17947020113271e-18 BR00118043 LPAR1 final crispr L01 A549 96 1855 Hole +0.14738838961690223 5.884234778585601e-17 BR00118044 LPAR1 final crispr L01 A549 96 1740 Hole +0.25327966562720167 7.54087452741926e-17 BR00118043 AURKB final crispr C13 A549 96 577 Hole +0.12357121192426015 3.870207775046484e-16 BR00118041 TUBB final crispr J17 A549 96 2352 Hole +0.11964509394572025 2.031694905264971e-15 BR00118041 CACNG1 final crispr L02 A549 96 2400 Hole +0.4450067476383266 2.772406078866182e-14 BR00118042 AURKB final crispr C13 A549 96 152 Hole +0.1321731943987998 4.336378882289304e-14 BR00118044 SLC29A1 final crispr N21 A549 96 1789 Hole +0.12696149356595163 1.65120443162204e-13 BR00118043 UGT1A9 final crispr J01 A549 96 1854 Hole +0.12591643303560057 4.0024950842296313e-13 BR00118043 PTK2B final crispr N15 A549 96 1837 Hole +0.11318024862267727 3.1587582383120478e-12 BR00118041 CDK2 final crispr L19 A549 96 2107 Hole +0.1334696134521104 3.301325397500948e-12 BR00118044 HCK final crispr H23 A549 96 1515 Hole +0.13492118640968437 3.3391426334357868e-12 BR00118044 S1PR2 final crispr J23 A549 96 1478 Hole +0.12239408423277778 6.663815003834048e-12 BR00118043 HSD11B1 final crispr O01 A549 96 1752 Hole +0.12026715494829998 1.8692036283874187e-11 BR00118044 LYN final crispr N13 A549 96 1748 Hole +0.12822086958036172 2.7134896459745036e-11 BR00118044 JAK1 final crispr J09 A549 96 1515 Hole +0.09469682480004722 5.249469025108677e-11 BR00118041 AGER final crispr J18 A549 96 2707 Hole +0.12184755163932766 8.08447171458055e-11 BR00118044 OPRM1 final crispr P22 A549 96 1604 Hole +0.11630837853174446 1.0027677589966725e-10 BR00118044 GJB4 final crispr N01 A549 96 1740 Hole +0.1766304347826087 1.9193198632750309e-10 BR00118043 PPAT final crispr E13 A549 96 736 Hole +0.27118079089767666 2.8947967142317484e-10 BR00118044 PLK1 final crispr G09 A549 96 301 Hole +0.2706270627062706 3.6198183012506346e-10 BR00118044 PLK1 final crispr F13 A549 96 303 Hole +0.29265197275414473 6.018612740089428e-10 BR00118043 PLK1 final crispr G09 A549 96 251 Hole +0.10854289799669395 6.674878613097717e-10 BR00118044 TNF final crispr N17 A549 96 1845 Hole +0.12027074600921922 9.225491039872927e-10 BR00118044 KCNQ2 final crispr P13 A549 96 1476 Hole +0.17610591389025657 1.180105534246033e-09 BR00118041 FOXM1 final crispr A19 A549 96 675 Hole +0.14037745879851143 1.721570779411556e-09 BR00118043 MAPK8 final crispr D07 A549 96 1045 Hole +0.10392884690073227 1.8117173902982867e-09 BR00118043 S1PR2 final crispr J23 A549 96 1919 Hole +0.10680686220254565 2.1577191059370884e-09 BR00118044 PORCN final crispr L13 A549 96 1807 Hole +0.10084872690963555 2.760489915418602e-09 BR00118041 EZH2 final crispr H09 A549 96 2003 Hole +0.11354025935230277 4.0476247257934995e-09 BR00118044 UGT1A9 final crispr J01 A549 96 1538 Hole +0.08873000226364637 6.539206201655152e-09 BR00118041 AKR1B1 final crispr L21 A549 96 2467 Hole +0.11318242343541944 8.504145492328773e-09 BR00118043 OPRM1 final crispr P22 A549 96 1502 Hole +0.08219516251545225 8.638458005477082e-09 BR00118041 FOXM1 final crispr F23 A549 96 2840 Hole +0.10400698011855275 8.978621664368375e-09 BR00118044 GAA final crispr L17 A549 96 1765 Hole +0.10293303818483675 9.414397647528873e-09 BR00118044 HSD11B1 final crispr O01 A549 96 1807 Hole +0.17141487844913314 9.510776355558868e-09 BR00118044 PPAT final crispr E13 A549 96 647 Hole +0.10800303145130731 1.0712861690528637e-08 BR00118043 GAA final crispr L18 A549 96 1625 Hole +0.10882163554410818 1.998617581237449e-08 BR00118043 HCK final crispr H23 A549 96 1553 Hole +0.10020042685961834 2.166088622682491e-08 BR00118044 AKR1B1 final crispr H17 A549 96 1818 Hole +0.1013186595280587 5.993197724533549e-08 BR00118044 MET final crispr H13 A549 96 1680 Hole +0.27155172413793105 6.218934438824865e-08 BR00118044 RPL23A final crispr M18 A549 96 232 Hole +0.10036271029479858 8.712731865770108e-08 BR00118043 PDPK1 final crispr N18 A549 96 1672 Hole +0.4284221525600836 1.0240268633734942e-07 BR00118042 PLK1 final crispr G09 A549 96 87 Hole +0.0979278625030259 1.4484007894986225e-07 BR00118044 AKT1 final crispr J19 A549 96 1700 Hole +0.09023908878565992 2.2404586003407088e-07 BR00118041 GJB4 final crispr N01 A549 96 1954 Hole +0.13007755830822454 2.387855301193839e-07 BR00118044 CLK1 final crispr M11 A549 96 927 Hole +0.08054062062886574 2.4360121721263624e-07 BR00118041 PORCN final crispr L13 A549 96 2443 Hole +0.12864592984187298 2.511776375479164e-07 BR00118041 GUCY1B1 final crispr N08 A549 96 946 Hole +0.14995298471896026 3.90711408762327e-07 BR00118043 S1PR1 final crispr P23 A549 96 682 Hole +0.25494752623688155 4.438151188335534e-07 BR00118042 SIRT2 final crispr P01 A549 96 230 Hole +0.09488414958584024 4.443217802659956e-07 BR00118043 CACNG1 final crispr N23 A549 96 1684 Hole +0.0867116809539231 4.4743981515024846e-07 BR00118041 LPAR1 final crispr L01 A549 96 2026 Hole +0.20922326317701712 4.860977635331818e-07 BR00118042 PPAT final crispr E13 A549 96 339 Hole +0.4218354430379747 6.421055893440817e-07 BR00118042 RPL23A final crispr G14 A549 96 80 Hole +0.09297987899023956 6.948601004563144e-07 BR00118044 F10 final crispr H15 A549 96 1712 Hole +0.09712376866898234 1.0451550737786153e-06 BR00118044 ELANE final crispr N19 A549 96 1526 Hole +0.09746328437917223 1.2984552057874679e-06 BR00118043 F10 final crispr H15 A549 96 1498 Hole +0.09334413672751363 1.341773329644253e-06 BR00118043 SCNN1G final crispr P15 A549 96 1623 Hole +0.07302954396492542 1.415262059043154e-06 BR00118041 PTK2B final crispr N15 A549 96 2637 Hole +0.15452930728241562 2.7805863116846687e-06 BR00118042 PPAT final crispr G13 A549 96 563 Hole +0.11099924018630768 2.9609446042776196e-06 BR00118041 GPR119 final crispr G23 A549 96 1084 Hole +0.12124582869855395 3.5526459194923145e-06 BR00118041 CCR1 final crispr O17 A549 96 899 Hole +0.09714285714285714 3.6006384641072565e-06 BR00118041 PDE3A final crispr O08 A549 96 1400 Hole +0.09460051629648565 3.928291851275478e-06 BR00118044 S1PR1 final crispr P23 A549 96 1461 Hole +0.16116158125144003 4.420193272391093e-06 BR00118042 COMT final crispr M02 A549 96 492 Hole +0.14419326959433912 5.3983239083068914e-06 BR00118043 FOXM1 final crispr A19 A549 96 612 Hole +0.10523585665266887 5.748887959118934e-06 BR00118041 AKT1 final crispr F06 A549 96 1136 Hole +0.13708516346650457 6.229827363203734e-06 BR00118044 CDK7 final crispr I14 A549 96 661 Hole +0.2312951712093343 6.318144092474137e-06 BR00118043 RPL23A final crispr M18 A549 96 233 Hole +0.163135593220339 6.715214915484447e-06 BR00118043 TUBB3 final crispr K11 A549 96 472 Hole +0.09035712749021127 6.775620718965377e-06 BR00118044 TUBB final crispr J17 A549 96 1525 Hole +0.1290417626068073 6.889790679171479e-06 BR00118043 CYP3A4 final crispr D20 A549 96 741 Hole +0.14988534500729622 1.1261546178876306e-05 BR00118041 HDAC3 final crispr K19 A549 96 531 Hole +0.08446013659302055 1.2219875848916098e-05 BR00118043 RGS4 final crispr N11 A549 96 1674 Hole +0.0759493670886076 1.418282269045804e-05 BR00118041 F10 final crispr H15 A549 96 2054 Hole +0.07627913055626913 1.6797572356511238e-05 BR00118041 PLA2G1B final crispr J11 A549 96 1998 Hole +0.08196529143873454 1.71753052105182e-05 BR00118044 RPL3 final crispr H11 A549 96 1726 Hole +0.17633320358115998 1.8884465742711708e-05 BR00118041 TUBB3 final crispr K11 A549 96 367 Hole +0.11970074812967581 2.0025344271325602e-05 BR00118042 KCNJ1 final crispr E14 A549 96 802 Hole +0.19436323366555924 2.0269926938405568e-05 BR00118043 RPL23A final crispr G14 A549 96 301 Hole +0.09778941574407705 2.282552140789248e-05 BR00118044 LPAR1 final crispr B16 A549 96 1174 Hole +0.08610567514677103 2.292761349375494e-05 BR00118043 CACNG1 final crispr L02 A549 96 1533 Hole +0.11113511258761573 2.5504235262816866e-05 BR00118041 HDAC3 final crispr G07 A549 96 897 Hole +0.09845380037504163 4.089408233053979e-05 BR00118042 S1PR4 final crispr H05 A549 96 1101 Hole +0.10718113612004287 4.362817090281178e-05 BR00118041 GABRB2 final crispr L22 A549 96 933 Hole +0.09930914765653767 4.777348045161104e-05 BR00118044 CDK2 final crispr L19 A549 96 1066 Hole +0.08577016276696041 4.8748919748354614e-05 BR00118043 BTK final crispr P17 A549 96 1434 Hole +0.2014859068627451 5.066694912247184e-05 BR00118041 AURKB final crispr C13 A549 96 255 Hole +0.09706002380132008 5.294218797525703e-05 BR00118041 FFAR4 final crispr E04 A549 96 1109 Hole 0.20110998998979807 6.022766558395755e-49 BR00118041 LYN final crispr N13 A549 96 2739 Interphase 0.17629627807103307 1.2860449539632545e-38 BR00118041 MAPK8 final crispr D07 A549 96 2807 Interphase 0.1873471424912091 9.57129333715662e-36 BR00118044 PTK2B final crispr N15 A549 96 2302 Interphase @@ -679,6 +6709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.17547126172608563 1.9201569418104566e-25 BR00118043 LPAR1 final crispr L01 A549 96 1855 Interphase 0.155106915377616 3.5897506874157767e-25 BR00118041 TUBB final crispr J17 A549 96 2352 Interphase 0.14602691462961415 1.3643015488238253e-24 BR00118041 RGS4 final crispr N11 A549 96 2591 Interphase +0.17054821013823573 9.19840194302815e-24 BR00118043 PTK2B final crispr N15 A549 96 1837 Interphase +0.31068146405062486 2.8130651053577027e-23 BR00118044 AURKB final crispr C13 A549 96 533 Interphase +0.17554129496466297 1.1398406072233225e-22 BR00118044 AKR1B1 final crispr L21 A549 96 1649 Interphase +0.16525707559148747 3.05393371396824e-22 BR00118043 GJB4 final crispr N01 A549 96 1829 Interphase +0.1430767223382046 7.210019535815344e-22 BR00118041 CACNG1 final crispr L02 A549 96 2400 Interphase +0.12233104300813694 5.990681723212643e-19 BR00118041 FOXM1 final crispr F23 A549 96 2840 Interphase +0.12266767289713497 3.265615139948355e-18 BR00118041 AGER final crispr J18 A549 96 2707 Interphase +0.14697892129794665 5.952376483426992e-18 BR00118043 UGT1A9 final crispr J01 A549 96 1854 Interphase +0.14942045994245812 1.808210277999486e-17 BR00118044 LYN final crispr N13 A549 96 1748 Interphase +0.14722208560187552 1.9115746893427194e-17 BR00118041 KRAS final crispr F07 A549 96 1797 Interphase +0.231717643092225 1.9241933533624232e-17 BR00118044 GRIN2A final crispr A23 A549 96 722 Interphase +0.14866912123731477 3.182219657189891e-17 BR00118044 LPAR1 final crispr L01 A549 96 1740 Interphase +0.1427580733304433 2.2417670515186364e-16 BR00118044 SLC29A1 final crispr N21 A549 96 1789 Interphase +0.13622129491116186 2.990513632769726e-16 BR00118041 GJB4 final crispr N01 A549 96 1954 Interphase +0.2172435593488225 4.298863037681905e-15 BR00118044 FFAR2 final crispr A24 A549 96 703 Interphase +0.20208604954367665 4.096273096586461e-14 BR00118044 FFAR2 final crispr A06 A549 96 767 Interphase +0.13156880815149197 1.1132316019667349e-13 BR00118043 HSD11B1 final crispr O01 A549 96 1752 Interphase +0.13130699288702377 1.5331205572608375e-13 BR00118044 GJB4 final crispr N01 A549 96 1740 Interphase +0.1283895960154953 2.1517882448444764e-13 BR00118044 PORCN final crispr L13 A549 96 1807 Interphase +0.18880747332698913 2.4225247892362765e-13 BR00118043 PDPK1 final crispr E16 A549 96 823 Interphase +0.12661183655473848 3.817982310453375e-13 BR00118044 AKR1B1 final crispr H17 A549 96 1818 Interphase +0.19573901464713714 5.398008710629855e-13 BR00118043 KCNMA1 final crispr A07 A549 96 751 Interphase +0.11982026959560658 6.09768893128117e-13 BR00118041 EZH2 final crispr H09 A549 96 2003 Interphase +0.1077168296843003 6.358185131887409e-13 BR00118041 AKR1B1 final crispr L21 A549 96 2467 Interphase +0.25253178194354664 7.33446011698488e-13 BR00118044 RPL3 final crispr K04 A549 96 441 Interphase +0.12367676981211849 9.68156210635845e-13 BR00118044 TNF final crispr N17 A549 96 1845 Interphase +0.10680589003931772 1.3231968080569375e-12 BR00118041 PORCN final crispr L13 A549 96 2443 Interphase +0.11996886426363766 1.7437523449035476e-12 BR00118043 S1PR2 final crispr J23 A549 96 1919 Interphase +0.2213540822741738 1.951496321821153e-12 BR00118043 GRIN2A final crispr A23 A549 96 557 Interphase +0.17621561675075365 2.43475438326393e-12 BR00118043 IGF1R final crispr E19 A549 96 877 Interphase +0.11474985270534435 4.318490822947615e-12 BR00118041 LPAR1 final crispr L01 A549 96 2026 Interphase +0.2132076424118523 1.0294617994509447e-11 BR00118044 OPRL1 final crispr A11 A549 96 564 Interphase +0.1770486147569262 1.1284607174471196e-11 BR00118044 ITGB2 final crispr A17 A549 96 818 Interphase +0.17773184903745598 1.4184492136239792e-11 BR00118043 TGFBR1 final crispr B08 A549 96 802 Interphase +0.09805697834539756 1.6766457843833623e-11 BR00118041 PTK2B final crispr N15 A549 96 2637 Interphase +0.1685782848311065 1.73062852725956e-11 BR00118041 SCNN1G final crispr G24 A549 96 888 Interphase +0.20041309700657292 1.730718726207459e-11 BR00118041 CDK7 final crispr I14 A549 96 626 Interphase +0.20722949076786218 3.845541206819858e-11 BR00118041 TGFBR1 final crispr P24 A549 96 569 Interphase +0.18822025565388398 6.015559195234022e-11 BR00118043 FFAR2 final crispr A06 A549 96 678 Interphase +0.11647671124580011 6.803074726931045e-11 BR00118044 GAA final crispr L17 A549 96 1765 Interphase +0.19525175471777415 8.662565206383164e-11 BR00118041 BTK final crispr D24 A549 96 618 Interphase +0.1667775559991129 1.1957845452470456e-10 BR00118043 CYP2A6 final crispr C07 A549 96 835 Interphase +0.1531305722159183 1.2459911562329065e-10 BR00118043 ELANE final crispr H10 A549 96 992 Interphase +0.12559064477197088 1.3042988250072704e-10 BR00118044 S1PR2 final crispr J23 A549 96 1478 Interphase +0.1780724589903032 1.680103748913341e-10 BR00118043 GHSR final crispr A09 A549 96 726 Interphase +0.17315706229018496 2.4759472746670405e-10 BR00118043 ALDH2 final crispr A10 A549 96 754 Interphase +0.1624916266607123 3.0504685866551724e-10 BR00118044 KRAS final crispr F07 A549 96 848 Interphase +0.17477164361875758 3.107487682516855e-10 BR00118044 KCNN4 final crispr K01 A549 96 729 Interphase +0.12162412811201964 3.3480761817062416e-10 BR00118044 JAK1 final crispr J09 A549 96 1515 Interphase +0.18263473053892215 3.7771278321544663e-10 BR00118041 VEGFA final crispr H02 A549 96 668 Interphase +0.17934075559353035 4.969576572339441e-10 BR00118044 PDE7A final crispr C22 A549 96 682 Interphase +0.12167159898933225 5.648767399013708e-10 BR00118044 KCNQ2 final crispr P13 A549 96 1476 Interphase +0.16624040920716113 7.546571895307084e-10 BR00118043 ADORA2A final crispr B22 A549 96 782 Interphase +0.11491549829480864 7.672682472734225e-10 BR00118043 GAA final crispr L18 A549 96 1625 Interphase +0.19841751645578254 8.091772310827601e-10 BR00118043 CDC25A final crispr D06 A549 96 545 Interphase +0.20094876660341557 8.187499731556065e-10 BR00118043 CDK4 final crispr B15 A549 96 527 Interphase +0.16895233166580415 8.767721110601794e-10 BR00118041 HSD11B1 final crispr O23 A549 96 744 Interphase +0.19103067561260556 9.559517475749212e-10 BR00118043 AURKB final crispr C13 A549 96 577 Interphase +0.14224825386349887 1.003721683212648e-09 BR00118043 MAPK8 final crispr D07 A549 96 1045 Interphase +0.1688749725335091 1.1739214322005887e-09 BR00118044 CCND1 final crispr B23 A549 96 738 Interphase +0.1691065783531537 1.2822185861655272e-09 BR00118043 ATP5F1D final crispr G21 A549 96 728 Interphase +0.15792139558043303 1.4022120292680914e-09 BR00118041 SLCO2B1 final crispr A21 A549 96 834 Interphase +0.16389244558258642 1.4288203732467977e-09 BR00118043 OPRL1 final crispr A04 A549 96 781 Interphase +0.1169488056985118 1.7973995643825542e-09 BR00118044 HCK final crispr H23 A549 96 1515 Interphase +0.11565919483826978 1.969086998646636e-09 BR00118044 UGT1A9 final crispr J01 A549 96 1538 Interphase +0.1670455218575998 2.075646903944694e-09 BR00118044 SIRT2 final crispr O19 A549 96 734 Interphase +0.14657391428590563 2.2088230192244115e-09 BR00118041 GUCY1B1 final crispr N08 A549 96 946 Interphase +0.1550222085026839 2.6900240037402764e-09 BR00118043 MMP2 final crispr E07 A549 96 836 Interphase +0.16265281972604248 2.7493287237420606e-09 BR00118041 CDC25A final crispr C14 A549 96 764 Interphase +0.1403860043183477 2.8322265194599942e-09 BR00118043 KCNK1 final crispr C17 A549 96 1029 Interphase +0.25742574257425743 3.137996741249157e-09 BR00118044 PLK1 final crispr F13 A549 96 303 Interphase +0.16615350970586035 3.5551659020067817e-09 BR00118044 CDC25A final crispr D06 A549 96 721 Interphase +0.14099790181693725 3.58269082273653e-09 BR00118041 BRD4 final crispr M19 A549 96 1003 Interphase +0.18451064734310926 3.594123815405529e-09 BR00118041 CDK7 final crispr E12 A549 96 581 Interphase +0.14237070302690086 4.062149066649984e-09 BR00118044 SCNN1G final crispr G24 A549 96 974 Interphase +0.1588310038119441 4.4414328709207804e-09 BR00118044 KCNMA1 final crispr A07 A549 96 787 Interphase +0.13608088872603252 4.471128090763442e-09 BR00118043 ERBB2 final crispr I11 A549 96 1067 Interphase +0.15001956947162426 4.9407707917638734e-09 BR00118043 ITGB2 final crispr A17 A549 96 876 Interphase +0.15547263681592038 6.790354083651643e-09 BR00118044 ASIC1 final crispr M20 A549 96 804 Interphase +0.1068521429987819 7.738001386931036e-09 BR00118044 MET final crispr H13 A549 96 1680 Interphase +0.14773960121762394 8.276945433557544e-09 BR00118041 PLA2G1B final crispr L20 A549 96 871 Interphase +0.0960521138662689 8.515659979658546e-09 BR00118043 AGER final crispr J18 A549 96 2077 Interphase +0.09778738217957827 9.329436634589403e-09 BR00118041 PLA2G1B final crispr J11 A549 96 1998 Interphase +0.1507177033492823 1.0643060658364455e-08 BR00118044 PDPK1 final crispr E16 A549 96 836 Interphase +0.13417191942007378 1.3822411181481661e-08 BR00118043 PTGIR final crispr G08 A549 96 1039 Interphase +0.15927886679067105 1.598750446941627e-08 BR00118043 KCNN4 final crispr A22 A549 96 723 Interphase +0.11020804204957338 1.6202499835081384e-08 BR00118044 ELANE final crispr N19 A549 96 1526 Interphase +0.13345828983581665 1.9197298764006558e-08 BR00118041 KCNJ1 final crispr E14 A549 96 1025 Interphase +0.16650509535049268 2.1429410793616417e-08 BR00118043 HSD11B1 final crispr O23 A549 96 651 Interphase +0.13863807205627046 2.1570896772540663e-08 BR00118043 KCNQ2 final crispr A16 A549 96 947 Interphase 0.3491847826086957 3.327206807630566e-40 BR00118043 PPAT final crispr E13 A549 96 736 Large 0.1548744998557137 4.717211833561739e-33 BR00118041 UGT1A9 final crispr J01 A549 96 3112 Large 0.392468063563863 2.0270363831562253e-27 BR00118041 CA5A final crispr M01 A549 96 389 Large @@ -689,6 +6809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.410874861572536 3.70691291739821e-23 BR00118043 RPL23A final crispr G14 A549 96 301 Large 0.285586373903665 4.348176690375593e-23 BR00118041 CDK7 final crispr I14 A549 96 626 Large 0.3052649431318303 1.9100580855190905e-22 BR00118044 AURKB final crispr C13 A549 96 533 Large +0.34165108586221776 8.837984627296277e-22 BR00118041 PPAT final crispr E13 A549 96 408 Large +0.39344262295081966 1.8549961687242282e-21 BR00118041 FFAR2 final crispr A24 A549 96 305 Large +0.42446384803921566 4.4390661362019535e-21 BR00118041 AURKB final crispr C13 A549 96 255 Large +0.4087984746018464 8.407407223497965e-21 BR00118043 RPL3 final crispr K04 A549 96 269 Large +0.41044776119402987 1.3853679944107794e-20 BR00118042 CDK7 final crispr I14 A549 96 268 Large +0.2644396551724138 3.887808025234294e-20 BR00118041 PPAT final crispr G13 A549 96 640 Large +0.27484793417632064 3.497558097460022e-19 BR00118044 OPRL1 final crispr A11 A549 96 564 Large +0.33830883013444324 3.9854048538277933e-19 BR00118041 TUBB3 final crispr K11 A549 96 367 Large +0.298728813559322 5.574714431757929e-19 BR00118043 TUBB3 final crispr K11 A549 96 472 Large +0.1471847361100176 6.244121126721622e-19 BR00118041 GJB4 final crispr N01 A549 96 1954 Large +0.2978149248232829 1.0848822762082067e-18 BR00118044 CDK4 final crispr B15 A549 96 467 Large +0.24570467483180955 1.3458226182575551e-18 BR00118044 S1PR1 final crispr A18 A549 96 680 Large +0.27204142874735077 1.3951343927575157e-18 BR00118043 GRIN2A final crispr A23 A549 96 557 Large +0.27478940008867364 1.6304998483243665e-18 BR00118043 CDC25A final crispr D06 A549 96 545 Large +0.25924215416194024 1.7333523917939767e-18 BR00118043 FOXM1 final crispr A19 A549 96 612 Large +0.25198710805985886 1.8037088221519723e-18 BR00118044 PPAT final crispr E13 A549 96 647 Large +0.34422443100718864 2.0319228462836497e-18 BR00118042 PPAT final crispr E13 A549 96 339 Large +0.41562968515742127 2.052496675318967e-18 BR00118042 SIRT2 final crispr P01 A549 96 230 Large +0.285807775948621 2.591407906598935e-18 BR00118043 DHH final crispr F05 A549 96 497 Large +0.23337856173677068 5.227811240171739e-18 BR00118043 S1PR1 final crispr A18 A549 96 737 Large +0.6068441795635874 6.3076728713435194e-18 BR00118041 RPL23A final crispr M18 A549 96 103 Large +0.2995689655172414 9.959335189548439e-18 BR00118041 AVPR1A final crispr J07 A549 96 432 Large +0.2163509302025655 1.1188076739265167e-17 BR00118043 CDK7 final crispr E12 A549 96 841 Large +0.6727848101265823 1.5621012661393103e-17 BR00118042 RPL23A final crispr G14 A549 96 80 Large +0.29045362547760856 1.821954587691838e-17 BR00118041 ASIC1 final crispr M20 A549 96 453 Large +0.21294117647058824 2.7766395505327e-17 BR00118043 FGF1 final crispr I19 A549 96 850 Large +0.22665889221545696 5.5064167871690055e-17 BR00118041 TGFBR1 final crispr B08 A549 96 729 Large +0.24635332252836303 7.647719478881672e-17 BR00118044 FOXM1 final crispr A19 A549 96 617 Large +0.3055222088835534 9.089246066631252e-17 BR00118044 RPL23A final crispr G14 A549 96 391 Large +0.23327534329011435 1.336972898378187e-16 BR00118041 FOXM1 final crispr A19 A549 96 675 Large +0.1387778932750572 1.3864021998699847e-16 BR00118043 ELANE final crispr N19 A549 96 1915 Large +0.2595600816343359 1.7442112100977566e-16 BR00118043 CDK2 final crispr F08 A549 96 542 Large +0.21572435002167167 4.94643356279238e-16 BR00118041 CDC25A final crispr C14 A549 96 764 Large +0.24150980328189736 5.026648211260805e-16 BR00118041 CDK9 final crispr I20 A549 96 609 Large +0.3728633851690014 5.525044490833158e-16 BR00118043 PLK1 final crispr G09 A549 96 251 Large +0.1456933537818831 8.376190594126326e-16 BR00118044 CACNG1 final crispr N23 A549 96 1653 Large +0.21686746987951808 8.545029100034302e-16 BR00118043 CDK7 final crispr I14 A549 96 747 Large +0.24386205338430578 1.1966667512657159e-15 BR00118043 AURKB final crispr C13 A549 96 577 Large +0.38362068965517243 1.3206868036994008e-15 BR00118044 RPL23A final crispr M18 A549 96 232 Large +0.1794253033895941 1.3662658240179246e-15 BR00118044 PPAT final crispr G13 A549 96 1070 Large +0.2756435907696412 2.300751001205069e-15 BR00118044 RPL3 final crispr K04 A549 96 441 Large +0.3064223341992426 2.350678900235803e-15 BR00118042 FOXM1 final crispr A19 A549 96 359 Large +0.2717391304347826 2.3915974227336666e-15 BR00118041 OPRL1 final crispr A11 A549 96 460 Large +0.19242735952123194 5.4696958309782385e-15 BR00118044 HSP90AB1 final crispr B04 A549 96 899 Large +0.21522572798870135 5.9200368673801894e-15 BR00118041 HRH4 final crispr A08 A549 96 715 Large +0.20015795821960639 7.757016537531814e-15 BR00118043 AVPR1A final crispr J07 A549 96 822 Large +0.20905459387483355 8.929270622279578e-15 BR00118043 KCNMA1 final crispr A07 A549 96 751 Large +0.34572490706319703 1.1820332730006633e-14 BR00118041 RPL23A final crispr G14 A549 96 269 Large +0.21768600458865944 1.6477719126857177e-14 BR00118043 FFAR2 final crispr A06 A549 96 678 Large +0.20767725425259673 2.7914770437242067e-14 BR00118043 ATP5F1D final crispr G21 A549 96 728 Large +0.21771771771771772 3.0965363222166046e-14 BR00118041 HRH4 final crispr H24 A549 96 666 Large +0.21709531013615735 3.1680975971264257e-14 BR00118044 CDK7 final crispr I14 A549 96 661 Large +0.20674620528288912 3.5827954189828825e-14 BR00118041 FPR1 final crispr N22 A549 96 729 Large +0.18873494634573032 4.36295869920834e-14 BR00118043 IGF1R final crispr E19 A549 96 877 Large +0.18635820910819245 5.840047156710781e-14 BR00118043 ASIC1 final crispr M20 A549 96 883 Large +0.20448076952346164 8.33841033130979e-14 BR00118043 CA5A final crispr M01 A549 96 724 Large +0.17599203125032975 1.3113828689196483e-13 BR00118044 SCNN1G final crispr G24 A549 96 974 Large +0.10780729383987922 1.366844772448442e-13 BR00118041 RGS4 final crispr N11 A549 96 2591 Large +0.1981747066492829 1.3824942073960528e-13 BR00118044 FFAR2 final crispr A06 A549 96 767 Large +0.17807460669733144 1.4532699889874175e-13 BR00118043 MET final crispr H13 A549 96 947 Large +0.2456249313424764 2.2149831914987425e-13 BR00118042 OPRL1 final crispr A04 A549 96 486 Large +0.23473201818767678 2.858889056422814e-13 BR00118043 CDK4 final crispr B15 A549 96 527 Large +0.21144038756941982 2.8997703529115453e-13 BR00118041 COMT final crispr M02 A549 96 650 Large +0.3125128839414554 3.0803042396222093e-13 BR00118041 CDK2 final crispr F08 A549 96 297 Large +0.19904410657835314 3.694827501011446e-13 BR00118043 SLC7A11 final crispr P05 A549 96 728 Large +0.12587526500071378 4.020182263988663e-13 BR00118043 PTK2B final crispr N15 A549 96 1837 Large +0.1868583344556545 5.068008773340639e-13 BR00118043 PDPK1 final crispr E16 A549 96 823 Large +0.20446709574372163 5.092794143188993e-13 BR00118043 S1PR1 final crispr P23 A549 96 682 Large +0.18801691729323308 7.054377886458624e-13 BR00118043 TNNC1 final crispr D09 A549 96 798 Large +0.20566318926974664 7.871827300666222e-13 BR00118043 COMT final crispr A12 A549 96 671 Large +0.18687771885422919 8.918669491530505e-13 BR00118043 TGFBR1 final crispr B08 A549 96 802 Large +0.19478956877147258 9.924479154273254e-13 BR00118044 SIRT2 final crispr O19 A549 96 734 Large +0.1960801216844251 1.0568672980225577e-12 BR00118044 GRIN2A final crispr A23 A549 96 722 Large +0.1948704248941838 1.3141164699422102e-12 BR00118043 GHSR final crispr A09 A549 96 726 Large +0.2147280026353845 1.3636126859660146e-12 BR00118041 CYP1A2 final crispr M15 A549 96 598 Large +0.1882202304737516 1.6621204648997556e-12 BR00118043 OPRL1 final crispr A04 A549 96 781 Large +0.18964892857512392 2.0600535240232963e-12 BR00118044 GRIN2A final crispr P09 A549 96 762 Large +0.18500738787624033 2.104421955309773e-12 BR00118043 MME final crispr H08 A549 96 792 Large +0.18288208558957206 2.1223118345715087e-12 BR00118044 ITGB2 final crispr A17 A549 96 818 Large +0.10047299571787367 2.332552961118627e-12 BR00118041 AGER final crispr J18 A549 96 2707 Large +0.2151580459770115 3.1394861183642535e-12 BR00118041 HSP90AB1 final crispr B04 A549 96 576 Large +0.16832660085036008 3.1941750895991376e-12 BR00118041 ITGB2 final crispr A17 A549 96 945 Large +0.1921816360147401 3.2159556313644713e-12 BR00118044 KCNN4 final crispr K01 A549 96 729 Large +0.10826904656903151 3.4591674010354417e-12 BR00118044 PTK2B final crispr N15 A549 96 2302 Large +0.17840448135986092 3.8093320649806576e-12 BR00118043 CYP2A6 final crispr C07 A549 96 835 Large +0.1779374265822422 4.2515569542776195e-12 BR00118044 DHH final crispr F05 A549 96 835 Large +0.4092442645074224 4.392169299887196e-12 BR00118042 AURKB final crispr C13 A549 96 152 Large +0.11152954688169521 4.680221376542581e-12 BR00118041 AKR1B1 final crispr H17 A549 96 2137 Large +0.22386397386397386 6.003027907040348e-12 BR00118042 CDK7 final crispr E12 A549 96 518 Large +0.2287065868263473 6.051485026458142e-12 BR00118041 HTR3A final crispr O20 A549 96 501 Large 0.3220374315868322 5.441921898202953e-25 BR00118044 AURKB final crispr C13 A549 96 533 Metaphase 0.5391363022941971 4.50315527515377e-21 BR00118042 AURKB final crispr C13 A549 96 152 Metaphase 0.33022427164116536 3.084470015604948e-18 BR00118041 TUBB3 final crispr K11 A549 96 367 Metaphase @@ -699,6 +6909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.256258342226754 3.071091537372456e-17 BR00118043 AURKB final crispr C13 A549 96 577 Metaphase 0.2817796610169492 6.614980778100066e-17 BR00118043 TUBB3 final crispr K11 A549 96 472 Metaphase 0.3676319291073952 7.296420122697846e-17 BR00118043 RPL3 final crispr K04 A549 96 269 Metaphase +0.3473532668881506 1.621675031593698e-16 BR00118043 RPL23A final crispr G14 A549 96 301 Metaphase +0.3735906862745098 2.5278147379213653e-16 BR00118041 AURKB final crispr C13 A549 96 255 Metaphase +0.14058355437665782 1.9080253283885335e-15 BR00118044 GJB4 final crispr N01 A549 96 1740 Metaphase +0.2244214672575086 2.1945979457592808e-15 BR00118041 FOXM1 final crispr A19 A549 96 675 Metaphase +0.21331521739130435 4.5085784351125995e-15 BR00118043 PPAT final crispr E13 A549 96 736 Metaphase +0.27102122900442227 7.127274717302377e-15 BR00118044 RPL3 final crispr K04 A549 96 441 Metaphase +0.34328358208955223 2.134719975985307e-14 BR00118042 CDK7 final crispr I14 A549 96 268 Metaphase +0.3639055472263868 3.571568481793346e-14 BR00118042 SIRT2 final crispr P01 A549 96 230 Metaphase +0.30020155883701416 4.468462679734024e-14 BR00118042 PPAT final crispr E13 A549 96 339 Metaphase +0.281507439233657 4.5066750238858325e-14 BR00118041 CA5A final crispr M01 A549 96 389 Metaphase +0.2300729504639484 5.70537164611589e-14 BR00118041 CDK7 final crispr E12 A549 96 581 Metaphase +0.2775392765801973 6.922528274281233e-14 BR00118044 RPL23A final crispr G14 A549 96 391 Metaphase +0.25217391304347825 2.9719200993322607e-13 BR00118041 OPRL1 final crispr A11 A549 96 460 Metaphase +0.09710892003562094 3.2083260204354647e-13 BR00118041 UGT1A9 final crispr J01 A549 96 3112 Metaphase +0.2277137575845032 8.995304331653074e-13 BR00118043 CDK2 final crispr F08 A549 96 542 Metaphase +0.1950352592708834 2.067392910666963e-12 BR00118041 HRH4 final crispr A08 A549 96 715 Metaphase +0.19234665081874688 2.4925502959804322e-12 BR00118041 TGFBR1 final crispr B08 A549 96 729 Metaphase +0.1908286918560891 3.962573941069904e-12 BR00118043 SLC7A11 final crispr P05 A549 96 728 Metaphase +0.5599683544303797 4.763980159660693e-12 BR00118042 RPL23A final crispr G14 A549 96 80 Metaphase +0.1794087981039956 8.339572698447822e-12 BR00118043 TGFBR1 final crispr B08 A549 96 802 Metaphase +0.19821533953318005 2.621443186560641e-11 BR00118041 CDK7 final crispr I14 A549 96 626 Metaphase +0.3232758620689655 4.014771621397197e-11 BR00118044 RPL23A final crispr M18 A549 96 232 Metaphase +0.19940852374007453 4.4535058047189554e-11 BR00118043 FOXM1 final crispr A19 A549 96 612 Metaphase +0.5094043887147336 4.825730593435314e-11 BR00118042 PLK1 final crispr G09 A549 96 87 Metaphase +0.3003411982419616 5.5868017432596573e-11 BR00118042 TUBB3 final crispr K11 A549 96 262 Metaphase +0.18535613538683487 9.733332701690384e-11 BR00118043 S1PR1 final crispr P23 A549 96 682 Metaphase +0.27463638484872055 1.6444330287806955e-10 BR00118044 PLK1 final crispr G09 A549 96 301 Metaphase +0.10770700469779282 2.505706224070864e-10 BR00118041 GJB4 final crispr N01 A549 96 1954 Metaphase +0.1909752402711898 4.436426266533058e-10 BR00118042 PRKCE final crispr I17 A549 96 601 Metaphase +0.09454063113619254 4.817536798578266e-10 BR00118041 AKR1B1 final crispr L21 A549 96 2467 Metaphase +0.15942341188125267 8.852600788898758e-10 BR00118043 CDK7 final crispr E12 A549 96 841 Metaphase +0.2504651376991803 1.314184793436099e-09 BR00118042 TUBB final crispr K13 A549 96 330 Metaphase +0.18635295168647859 1.3583634010271537e-09 BR00118041 CYP1A2 final crispr M15 A549 96 598 Metaphase +0.1898227969348659 1.373025132231701e-09 BR00118041 HSP90AB1 final crispr B04 A549 96 576 Metaphase +0.10675426567116911 1.633381404157822e-09 BR00118043 GJB4 final crispr N01 A549 96 1829 Metaphase +0.43119266055045874 1.7733773075106592e-09 BR00118042 RPL3 final crispr K04 A549 96 109 Metaphase +0.18592964824120603 1.9644604265253146e-09 BR00118041 HIF1A final crispr M24 A549 96 597 Metaphase +0.19552827862046548 2.161626143384309e-09 BR00118041 HDAC3 final crispr K19 A549 96 531 Metaphase +0.26008383151240294 2.52707763213264e-09 BR00118041 CDK2 final crispr F08 A549 96 297 Metaphase +0.2101284410760261 2.7392358053971124e-09 BR00118041 ASIC1 final crispr M20 A549 96 453 Metaphase +0.18606219260669524 3.657435642312517e-09 BR00118042 SLC29A1 final crispr E03 A549 96 573 Metaphase +0.1882770870337478 3.886322980905994e-09 BR00118042 PPAT final crispr G13 A549 96 563 Metaphase +0.09788063405059072 4.008273134708331e-09 BR00118041 AKT1 final crispr J19 A549 96 2080 Metaphase +0.16338874146977564 4.0420273179895996e-09 BR00118041 IMPDH1 final crispr F15 A549 96 739 Metaphase +0.17097026080360528 5.224137000079461e-09 BR00118043 HDAC3 final crispr K19 A549 96 670 Metaphase +0.1561746272833904 5.430015482839423e-09 BR00118043 KCNJ1 final crispr E14 A549 96 797 Metaphase +0.25245901639344265 6.0376346290810525e-09 BR00118041 FFAR2 final crispr A24 A549 96 305 Metaphase +0.09797435707346004 6.263767078313145e-09 BR00118041 LPAR1 final crispr L01 A549 96 2026 Metaphase +0.1750788643533123 6.6705121800901355e-09 BR00118041 CHEK2 final crispr M07 A549 96 634 Metaphase +0.09134461038052206 8.567933647227953e-09 BR00118044 PTK2B final crispr N15 A549 96 2302 Metaphase +0.14578304116479823 9.170376499125741e-09 BR00118041 TUBB4B final crispr C04 A549 96 890 Metaphase +0.14941176470588236 1.0817491523690532e-08 BR00118043 FGF1 final crispr I19 A549 96 850 Metaphase +0.18801659537516482 1.1430414258106437e-08 BR00118041 MMP2 final crispr E07 A549 96 527 Metaphase +0.1942526451741096 1.388529272712332e-08 BR00118042 KCNQ2 final crispr A16 A549 96 491 Metaphase +0.2259005977903665 1.6042269404027872e-08 BR00118042 FOXM1 final crispr A19 A549 96 359 Metaphase +0.19075449101796407 1.9612358017190665e-08 BR00118041 HTR3A final crispr O20 A549 96 501 Metaphase +0.1865027770190294 1.9810351784698336e-08 BR00118041 ABL1 final crispr P20 A549 96 523 Metaphase +0.10158836261265966 2.1027042981983468e-08 BR00118044 GAA final crispr L17 A549 96 1765 Metaphase +0.16377404110341795 2.32566651728662e-08 BR00118043 BTK final crispr D24 A549 96 675 Metaphase +0.15505155010166075 2.443522075843413e-08 BR00118043 IMPDH1 final crispr F15 A549 96 745 Metaphase +0.1726117057529877 2.6629248289701335e-08 BR00118043 CSF1R final crispr J15 A549 96 603 Metaphase +0.17304492512479203 2.833287626334853e-08 BR00118041 SLC7A11 final crispr P05 A549 96 601 Metaphase +0.1894315387273134 2.9194874447739472e-08 BR00118043 DHH final crispr F05 A549 96 497 Metaphase +0.07974355419999053 3.25776852445272e-08 BR00118041 MAPK8 final crispr D07 A549 96 2807 Metaphase +0.40242587601078167 4.127483070340769e-08 BR00118042 TUBB final crispr J17 A549 96 105 Metaphase +0.19304644148189082 4.476952246235352e-08 BR00118044 CDK4 final crispr B15 A549 96 467 Metaphase +0.17494451357161628 4.999814721169009e-08 BR00118041 FLT3 final crispr G16 A549 96 563 Metaphase +0.20454000671173114 5.235766823706079e-08 BR00118041 PPAT final crispr E13 A549 96 408 Metaphase +0.29840147042441795 5.691002717508923e-08 BR00118042 CDK2 final crispr F08 A549 96 188 Metaphase +0.15478867253902023 5.8291496284223674e-08 BR00118041 CATSPER4 final crispr P02 A549 96 720 Metaphase +0.15154390201828533 5.921639805263152e-08 BR00118041 HSD11B1 final crispr O23 A549 96 744 Metaphase +0.15791422825670373 6.092677865206027e-08 BR00118041 HBB final crispr M08 A549 96 681 Metaphase +0.17943503633955105 6.152137477939787e-08 BR00118043 CDK4 final crispr B15 A549 96 527 Metaphase +0.19422025129342202 6.424032944244864e-08 BR00118042 ITGB2 final crispr A17 A549 96 450 Metaphase +0.14966122574684323 6.493511886735648e-08 BR00118043 TGM2 final crispr B09 A549 96 765 Metaphase +0.22357087626548705 7.597913650293709e-08 BR00118041 ALDH2 final crispr O09 A549 96 333 Metaphase +0.28502415458937197 8.201089345283872e-08 BR00118042 TUBB4B final crispr J13 A549 96 207 Metaphase +0.17573070495549264 8.620267433548851e-08 BR00118043 CDC25A final crispr D06 A549 96 545 Metaphase +0.08876393800611056 9.316180246298856e-08 BR00118041 GRIN2A final crispr P09 A549 96 2132 Metaphase +0.30637154902760777 1.1477538307997486e-07 BR00118042 DDR2 final crispr A03 A549 96 172 Metaphase +0.18043028954982973 1.2091080837652958e-07 BR00118041 COMT final crispr A12 A549 96 505 Metaphase +0.16043613707165108 1.255734809770472e-07 BR00118041 CYP2A6 final crispr C07 A549 96 642 Metaphase +0.17024431488352137 1.3780005234949303e-07 BR00118044 OPRL1 final crispr A11 A549 96 564 Metaphase +0.1461875047299296 1.396076827907611e-07 BR00118041 CDC25A final crispr C14 A549 96 764 Metaphase +0.09631286538131623 1.7771101512413628e-07 BR00118044 LPAR1 final crispr L01 A549 96 1740 Metaphase +0.13842482100238662 2.037974061155361e-07 BR00118043 S1PR4 final crispr H05 A549 96 838 Metaphase +0.15027443342776203 2.0554584635509705e-07 BR00118043 PLA2G1B final crispr L20 A549 96 706 Metaphase +0.17222222222222222 2.0740220509985573e-07 BR00118041 FGF1 final crispr J12 A549 96 540 Metaphase +0.1331126025132029 2.1678721915539946e-07 BR00118041 HDAC3 final crispr G07 A549 96 897 Metaphase +0.2483922577406908 2.2742760054546515e-07 BR00118042 OPRL1 final crispr A11 A549 96 254 Metaphase 0.14798601607544162 1.1757122716642715e-26 BR00118041 LYN final crispr N13 A549 96 2739 MetaphaseAlignment 0.12541739786728065 9.705667877352265e-20 BR00118041 MAPK8 final crispr D07 A549 96 2807 MetaphaseAlignment 0.25926878861623015 3.686630577988115e-16 BR00118041 MMP2 final crispr E07 A549 96 527 MetaphaseAlignment @@ -709,6 +7009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.22916221100169548 1.247409992791902e-13 BR00118041 TGFBR1 final crispr P24 A549 96 569 MetaphaseAlignment 0.11444087774304132 1.3547276346308421e-13 BR00118044 PTK2B final crispr N15 A549 96 2302 MetaphaseAlignment 0.12894299944659657 1.6613071007990442e-13 BR00118044 HSD11B1 final crispr O01 A549 96 1807 MetaphaseAlignment +0.18522861580539965 1.544219508948923e-12 BR00118043 TGFBR1 final crispr B08 A549 96 802 MetaphaseAlignment +0.34026345614328446 2.136768987032677e-12 BR00118043 RPL23A final crispr M18 A549 96 233 MetaphaseAlignment +0.1052615301196574 2.3516366098460196e-12 BR00118041 AKR1B1 final crispr L21 A549 96 2467 MetaphaseAlignment +0.1178416397658977 2.841482711231918e-12 BR00118041 GJB4 final crispr N01 A549 96 1954 MetaphaseAlignment +0.19086632545536655 3.873682345889984e-12 BR00118043 SLC7A11 final crispr P05 A549 96 728 MetaphaseAlignment +0.12248307533948295 7.173514309766417e-12 BR00118044 LPAR1 final crispr L01 A549 96 1740 MetaphaseAlignment +0.10514753672169505 8.727881745012205e-12 BR00118041 TUBB final crispr J17 A549 96 2352 MetaphaseAlignment +0.12086467343361094 1.0213494883977362e-11 BR00118044 GAA final crispr L17 A549 96 1765 MetaphaseAlignment +0.21742755889097354 1.7301187937971033e-11 BR00118041 HDAC3 final crispr K19 A549 96 531 MetaphaseAlignment +0.12057814376393892 1.7677679256319395e-11 BR00118044 GJB4 final crispr N01 A549 96 1740 MetaphaseAlignment +0.0938992786468547 2.3756111604883505e-11 BR00118041 FOXM1 final crispr F23 A549 96 2840 MetaphaseAlignment +0.10278214056223436 1.1698404024693825e-10 BR00118041 HCK final crispr H23 A549 96 2222 MetaphaseAlignment +0.1140011068068622 1.2094618359194175e-10 BR00118044 PORCN final crispr L13 A549 96 1807 MetaphaseAlignment +0.11873466252880166 1.3888276154834788e-10 BR00118044 AKR1B1 final crispr L21 A549 96 1649 MetaphaseAlignment +0.21473929097743116 1.862422247021703e-10 BR00118042 KCNQ2 final crispr A16 A549 96 491 MetaphaseAlignment +0.19764822583645042 1.911963154730695e-10 BR00118041 CDK7 final crispr E12 A549 96 581 MetaphaseAlignment +0.22569540636767527 1.9703497324780086e-10 BR00118044 RPL3 final crispr K04 A549 96 441 MetaphaseAlignment +0.158792113280348 2.306293445269636e-10 BR00118041 HDAC3 final crispr G07 A549 96 897 MetaphaseAlignment +0.18955149467857796 2.627974491157093e-10 BR00118041 CDK7 final crispr I14 A549 96 626 MetaphaseAlignment +0.10516066212268745 2.632152560491547e-10 BR00118041 F10 final crispr H15 A549 96 2054 MetaphaseAlignment +0.21822033898305085 2.9588579945350473e-10 BR00118043 TUBB3 final crispr K11 A549 96 472 MetaphaseAlignment +0.11141136654476007 3.359326410396039e-10 BR00118041 KRAS final crispr F07 A549 96 1797 MetaphaseAlignment +0.17426989666579512 3.566832305896823e-10 BR00118043 GHSR final crispr A09 A549 96 726 MetaphaseAlignment +0.1723808291645104 3.6642364894137553e-10 BR00118041 HSD11B1 final crispr O23 A549 96 744 MetaphaseAlignment +0.10207770090706948 3.734242633667159e-10 BR00118041 AKR1B1 final crispr H17 A549 96 2137 MetaphaseAlignment +0.3632350740685321 4.986639727640523e-10 BR00118041 RPL3 final crispr K04 A549 96 164 MetaphaseAlignment +0.09469934967148742 5.301108881844743e-10 BR00118041 PORCN final crispr L13 A549 96 2443 MetaphaseAlignment +0.23549793226779928 5.951723717452011e-10 BR00118041 CA5A final crispr M01 A549 96 389 MetaphaseAlignment +0.1038442336495257 8.051262762125562e-10 BR00118041 EZH2 final crispr H09 A549 96 2003 MetaphaseAlignment +0.21521739130434783 9.665522379025572e-10 BR00118041 OPRL1 final crispr A11 A549 96 460 MetaphaseAlignment +0.1881820976216536 1.2512911345915545e-09 BR00118041 AKR1C1 final crispr B13 A549 96 589 MetaphaseAlignment +0.11034616315662067 1.6339340764763677e-09 BR00118044 AKT1 final crispr J19 A549 96 1700 MetaphaseAlignment +0.10835515031145616 2.1911162142011077e-09 BR00118044 LYN final crispr N13 A549 96 1748 MetaphaseAlignment +0.2342500823427254 2.5699237535445542e-09 BR00118041 TUBB3 final crispr K11 A549 96 367 MetaphaseAlignment +0.10860775014147511 2.5923717002197475e-09 BR00118044 RPL3 final crispr H11 A549 96 1726 MetaphaseAlignment +0.1720458731746693 2.876779402848838e-09 BR00118043 S1PR1 final crispr P23 A549 96 682 MetaphaseAlignment +0.17847160929685202 4.252068200734248e-09 BR00118041 TNNC1 final crispr D09 A549 96 618 MetaphaseAlignment +0.09932068136170187 4.883609782427966e-09 BR00118041 PLA2G1B final crispr J11 A549 96 1998 MetaphaseAlignment +0.17005571943625042 5.02190051455231e-09 BR00118043 FFAR2 final crispr A06 A549 96 678 MetaphaseAlignment +0.08585119661085418 6.919349120619346e-09 BR00118041 PTK2B final crispr N15 A549 96 2637 MetaphaseAlignment +0.1478644646924829 7.468927816940412e-09 BR00118044 TGFBR1 final crispr B08 A549 96 880 MetaphaseAlignment +0.10950333410695622 7.890027091372432e-09 BR00118044 OPRM1 final crispr P22 A549 96 1604 MetaphaseAlignment +0.15067753720193114 9.023455983551109e-09 BR00118043 TUBB final crispr K13 A549 96 833 MetaphaseAlignment +0.19020304106346173 9.309604116433005e-09 BR00118041 ABL1 final crispr P20 A549 96 523 MetaphaseAlignment +0.14268234060219376 9.450594602444851e-09 BR00118043 FPR1 final crispr I18 A549 96 931 MetaphaseAlignment +0.2034527898135938 9.793425805797281e-09 BR00118041 ASIC1 final crispr M20 A549 96 453 MetaphaseAlignment +0.2630763110605084 9.796500659615126e-09 BR00118043 RPL3 final crispr K04 A549 96 269 MetaphaseAlignment +0.15452443731132257 1.0284752078795373e-08 BR00118043 CSK final crispr B11 A549 96 792 MetaphaseAlignment +0.2415683962264151 1.0819651555675176e-08 BR00118041 CDK4 final crispr B15 A549 96 318 MetaphaseAlignment +0.23559187930445416 1.1281947896625869e-08 BR00118041 ALDH2 final crispr O09 A549 96 333 MetaphaseAlignment +0.16323398558355579 1.2480503386208285e-08 BR00118041 KCNN1 final crispr D01 A549 96 702 MetaphaseAlignment +0.2478626799557032 1.3555738879085084e-08 BR00118043 RPL23A final crispr G14 A549 96 301 MetaphaseAlignment +0.09273615408409025 1.9563285620186704e-08 BR00118041 GRIN2A final crispr P09 A549 96 2132 MetaphaseAlignment +0.2643841911764706 2.0943325311355586e-08 BR00118041 AURKB final crispr C13 A549 96 255 MetaphaseAlignment +0.11100751399936191 2.1999782864573135e-08 BR00118044 KCNQ2 final crispr P13 A549 96 1476 MetaphaseAlignment +0.17252931323283083 3.5579406785630226e-08 BR00118041 HIF1A final crispr M24 A549 96 597 MetaphaseAlignment +0.1538363471789931 3.946470504579305e-08 BR00118041 IMPDH1 final crispr F15 A549 96 739 MetaphaseAlignment +0.14439140811455847 4.912466791798952e-08 BR00118043 S1PR4 final crispr H05 A549 96 838 MetaphaseAlignment +0.15905322946675796 5.7652555999309705e-08 BR00118041 HBB final crispr M08 A549 96 681 MetaphaseAlignment +0.13901345291479822 6.233640245521374e-08 BR00118041 HBB final crispr F21 A549 96 892 MetaphaseAlignment +0.15365549998753075 6.624696070173766e-08 BR00118044 CDC25A final crispr D06 A549 96 721 MetaphaseAlignment +0.0854737708326558 6.799202813830502e-08 BR00118041 CACNG1 final crispr N23 A549 96 2338 MetaphaseAlignment +0.14177457734492255 7.501843349911019e-08 BR00118043 CDK7 final crispr E12 A549 96 841 MetaphaseAlignment +0.1336567462399343 7.632825800733952e-08 BR00118041 GUCY1B1 final crispr N08 A549 96 946 MetaphaseAlignment +0.08070035937155966 8.584947699453497e-08 BR00118041 RGS4 final crispr N11 A549 96 2591 MetaphaseAlignment +0.15413444079970307 8.951204969391339e-08 BR00118043 CHRM3 final crispr B17 A549 96 707 MetaphaseAlignment +0.19247787610619468 9.797754694845342e-08 BR00118042 TGFBR1 final crispr B08 A549 96 452 MetaphaseAlignment +0.18556701030927836 1.0309958493395314e-07 BR00118042 ADH1C final crispr P04 A549 96 485 MetaphaseAlignment +0.09507937766268237 1.0375910294869319e-07 BR00118044 TNF final crispr N17 A549 96 1845 MetaphaseAlignment +0.45445344129554655 1.0677259083577955e-07 BR00118042 CCND1 final crispr B23 A549 96 78 MetaphaseAlignment +0.23278688524590163 1.1718608935138904e-07 BR00118041 FFAR2 final crispr A24 A549 96 305 MetaphaseAlignment +0.10065479348237968 1.2512268686729728e-07 BR00118043 GAA final crispr L18 A549 96 1625 MetaphaseAlignment +0.09960831359520954 1.2692274593629522e-07 BR00118044 CACNG1 final crispr N23 A549 96 1653 MetaphaseAlignment +0.4462025316455696 1.2936373919469452e-07 BR00118042 RPL23A final crispr G14 A549 96 80 MetaphaseAlignment +0.13530545217904133 1.48835085945901e-07 BR00118041 SCNN1G final crispr G24 A549 96 888 MetaphaseAlignment +0.16198041440759886 1.5456712973597965e-07 BR00118041 BTK final crispr D24 A549 96 618 MetaphaseAlignment +0.22003315833103068 1.739272352941148e-07 BR00118042 TUBB final crispr K13 A549 96 330 MetaphaseAlignment +0.1824998477718143 1.811345790647777e-07 BR00118041 CLK1 final crispr N05 A549 96 481 MetaphaseAlignment +0.15930599369085174 1.945321392184897e-07 BR00118041 CHEK2 final crispr M07 A549 96 634 MetaphaseAlignment +0.17314095449500555 2.092278526423688e-07 BR00118043 CDK4 final crispr B15 A549 96 527 MetaphaseAlignment +0.09757876270424659 2.3695526241165792e-07 BR00118044 BTK final crispr P17 A549 96 1662 MetaphaseAlignment +0.24935740907338388 2.623704374772541e-07 BR00118043 PLK1 final crispr G09 A549 96 251 MetaphaseAlignment +0.1894955300127714 2.7438989787322983e-07 BR00118041 AVPR1A final crispr J07 A549 96 432 MetaphaseAlignment +0.25862068965517243 3.1606722721544055e-07 BR00118044 RPL23A final crispr M18 A549 96 232 MetaphaseAlignment +0.09001339586556116 3.4840977741451317e-07 BR00118043 ELANE final crispr N19 A549 96 1915 MetaphaseAlignment +0.12586622863302704 3.960672007269369e-07 BR00118043 RPL3 final crispr H11 A549 96 968 MetaphaseAlignment +0.15973377703826955 4.1530035202217635e-07 BR00118041 SLC7A11 final crispr P05 A549 96 601 MetaphaseAlignment +0.0856739102255472 4.311200517418121e-07 BR00118041 AKT1 final crispr J19 A549 96 2080 MetaphaseAlignment +0.1351143705255806 4.519376993617012e-07 BR00118041 PTGIR final crispr G10 A549 96 830 MetaphaseAlignment +0.15465751012502202 4.599483304585618e-07 BR00118041 AKR1C1 final crispr B06 A549 96 630 MetaphaseAlignment 0.21170946519724773 1.3312536515986299e-45 BR00118044 PTK2B final crispr N15 A549 96 2302 OutOfFocus 0.19058689502389906 5.959030544999719e-44 BR00118041 LYN final crispr N13 A549 96 2739 OutOfFocus 0.17835718895813407 1.8958231861304515e-39 BR00118041 MAPK8 final crispr D07 A549 96 2807 OutOfFocus @@ -719,6 +7109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.19043671031678452 1.9945742830253373e-29 BR00118043 GJB4 final crispr N01 A549 96 1829 OutOfFocus 0.1890580255222561 9.709187625208975e-28 BR00118044 GJB4 final crispr N01 A549 96 1740 OutOfFocus 0.1747395218224287 1.589720318022664e-26 BR00118041 GJB4 final crispr N01 A549 96 1954 OutOfFocus +0.1633255058638381 5.61315701028983e-25 BR00118041 CDK2 final crispr L19 A549 96 2107 OutOfFocus +0.35010414422179126 1.1284079676696621e-24 BR00118044 RPL3 final crispr K04 A549 96 441 OutOfFocus +0.3056745482296744 1.847073206071312e-24 BR00118041 CDK7 final crispr E12 A549 96 581 OutOfFocus +0.4406919162128424 4.287803241105793e-24 BR00118043 RPL3 final crispr K04 A549 96 269 OutOfFocus +0.1441338298674483 5.875418672734589e-24 BR00118041 RGS4 final crispr N11 A549 96 2591 OutOfFocus +0.47035653902606694 6.719332255018445e-24 BR00118043 RPL23A final crispr M18 A549 96 233 OutOfFocus +0.17476806946698867 9.614962657438695e-24 BR00118044 LPAR1 final crispr L01 A549 96 1740 OutOfFocus +0.1479740779401531 2.2231114428373525e-23 BR00118041 CACNG1 final crispr L02 A549 96 2400 OutOfFocus +0.2522385104236926 6.105907163426639e-23 BR00118043 TGFBR1 final crispr B08 A549 96 802 OutOfFocus +0.2839329683970615 8.538219322953254e-23 BR00118041 CDK7 final crispr I14 A549 96 626 OutOfFocus +0.326271186440678 1.2570222466004615e-22 BR00118043 TUBB3 final crispr K11 A549 96 472 OutOfFocus +0.4043853820598007 1.5191322726320696e-22 BR00118043 RPL23A final crispr G14 A549 96 301 OutOfFocus +0.1746127363132181 1.7104671736007183e-22 BR00118044 AKR1B1 final crispr L21 A549 96 1649 OutOfFocus +0.13603989109977857 2.7523711547983724e-22 BR00118041 AGER final crispr J18 A549 96 2707 OutOfFocus +0.1320000546103551 4.811486805535505e-22 BR00118041 FOXM1 final crispr F23 A549 96 2840 OutOfFocus +0.26188565992212554 5.089999498540416e-22 BR00118041 HRH4 final crispr A08 A549 96 715 OutOfFocus +0.16436081903707803 1.0240500513981133e-21 BR00118044 HSD11B1 final crispr O01 A549 96 1807 OutOfFocus +0.16250723478065235 1.8759302289346205e-21 BR00118044 AKR1B1 final crispr H17 A549 96 1818 OutOfFocus +0.1603351343543002 2.6783556955278478e-21 BR00118043 UGT1A9 final crispr J01 A549 96 1854 OutOfFocus +0.25900360537528677 2.0470176310376988e-20 BR00118043 FFAR2 final crispr A06 A549 96 678 OutOfFocus +0.3385229357194985 2.3939503702349125e-20 BR00118041 CA5A final crispr M01 A549 96 389 OutOfFocus +0.3130434782608696 2.589314682298496e-20 BR00118041 OPRL1 final crispr A11 A549 96 460 OutOfFocus +0.2458979376787596 6.507810172685037e-20 BR00118043 SLC7A11 final crispr P05 A549 96 728 OutOfFocus +0.15927146339261533 8.118589890604274e-20 BR00118044 LYN final crispr N13 A549 96 1748 OutOfFocus +0.15460249510404098 1.115804511706631e-19 BR00118044 TNF final crispr N17 A549 96 1845 OutOfFocus +0.15480158488049126 1.2021972554056681e-19 BR00118043 PTK2B final crispr N15 A549 96 1837 OutOfFocus +0.26955074875207985 1.307281164209499e-19 BR00118041 SLC7A11 final crispr P05 A549 96 601 OutOfFocus +0.2822915452101066 2.8922848392280725e-19 BR00118041 HDAC3 final crispr K19 A549 96 531 OutOfFocus +0.28280749150398266 3.881895465223183e-19 BR00118041 MMP2 final crispr E07 A549 96 527 OutOfFocus +0.2842647728307384 3.916450536926393e-19 BR00118041 ABL1 final crispr P20 A549 96 523 OutOfFocus +0.15456888192281198 4.12322484526482e-19 BR00118044 SLC29A1 final crispr N21 A549 96 1789 OutOfFocus +0.2709075298413318 8.575396263644672e-19 BR00118041 TGFBR1 final crispr P24 A549 96 569 OutOfFocus +0.14742178261337835 1.1329363744161847e-18 BR00118043 S1PR2 final crispr J23 A549 96 1919 OutOfFocus +0.27419255823471234 1.9842214277756916e-18 BR00118043 CDC25A final crispr D06 A549 96 545 OutOfFocus +0.1432850723914129 2.423838103946782e-18 BR00118041 EZH2 final crispr H09 A549 96 2003 OutOfFocus +0.2613065326633166 2.5450422278917942e-18 BR00118041 HIF1A final crispr M24 A549 96 597 OutOfFocus +0.2737961404890623 5.334521873467312e-18 BR00118043 CDK4 final crispr B15 A549 96 527 OutOfFocus +0.13018978291953723 7.778679177149409e-18 BR00118041 TUBB final crispr J17 A549 96 2352 OutOfFocus +0.23021965384394227 8.211429325447818e-18 BR00118041 HSD11B1 final crispr O23 A549 96 744 OutOfFocus +0.16036991499786082 8.97073311229019e-18 BR00118044 UGT1A9 final crispr J01 A549 96 1538 OutOfFocus +0.12583175843208272 1.8677480512841802e-17 BR00118041 AKR1B1 final crispr L21 A549 96 2467 OutOfFocus +0.22636484687083888 2.8456396017719654e-17 BR00118043 KCNMA1 final crispr A07 A549 96 751 OutOfFocus +0.24605678233438485 2.9636485176119937e-17 BR00118041 CHEK2 final crispr M07 A549 96 634 OutOfFocus +0.2740743656870657 3.065228835543557e-17 BR00118041 COMT final crispr A12 A549 96 505 OutOfFocus +0.28982300884955753 3.911372655570211e-17 BR00118042 TGFBR1 final crispr B08 A549 96 452 OutOfFocus +0.26455571818288015 3.939033403925185e-17 BR00118043 CDK2 final crispr F08 A549 96 542 OutOfFocus +0.22588270861828122 4.335222992380888e-17 BR00118041 IMPDH1 final crispr F15 A549 96 739 OutOfFocus +0.14499169894853348 5.61621284054002e-17 BR00118044 PORCN final crispr L13 A549 96 1807 OutOfFocus +0.25963937805028225 6.229475640254178e-17 BR00118043 GRIN2A final crispr A23 A549 96 557 OutOfFocus +0.28373450036469733 1.1427118929511979e-16 BR00118041 ASIC1 final crispr M20 A549 96 453 OutOfFocus +0.22442747520959247 1.232187004325208e-16 BR00118041 TGFBR1 final crispr B08 A549 96 729 OutOfFocus +0.22418478260869565 1.288577015078387e-16 BR00118043 PPAT final crispr E13 A549 96 736 OutOfFocus +0.14732994432340837 1.3544038769721963e-16 BR00118044 AKT1 final crispr J19 A549 96 1700 OutOfFocus +0.23423423423423423 1.9748146753418836e-16 BR00118041 HRH4 final crispr H24 A549 96 666 OutOfFocus +0.20281709474711732 2.0282519108942207e-16 BR00118041 SCNN1G final crispr G24 A549 96 888 OutOfFocus +0.11738677959215851 2.800600439482665e-16 BR00118041 PTK2B final crispr N15 A549 96 2637 OutOfFocus +0.1433617369311581 2.971559847827822e-16 BR00118044 GAA final crispr L17 A549 96 1765 OutOfFocus +0.14760802553267052 1.0446698153691077e-15 BR00118044 OPRM1 final crispr P22 A549 96 1604 OutOfFocus +0.26272654690618763 1.1017785130282858e-15 BR00118041 HTR3A final crispr O20 A549 96 501 OutOfFocus +0.2366032026226201 1.2134781862259607e-15 BR00118041 BTK final crispr D24 A549 96 618 OutOfFocus +0.21704425711275027 1.3651748243635728e-15 BR00118043 ATP5F1D final crispr G21 A549 96 728 OutOfFocus +0.2581956643759766 1.4703354685828605e-15 BR00118043 OPRL1 final crispr A11 A549 96 511 OutOfFocus +0.18775933609958506 2.894676869489671e-15 BR00118043 NAMPT final crispr I09 A549 96 964 OutOfFocus +0.21165382677953085 2.9914448095801413e-15 BR00118043 ALDH2 final crispr A10 A549 96 754 OutOfFocus +0.25018167589021184 3.681517382116424e-15 BR00118041 RNASE1 final crispr I13 A549 96 534 OutOfFocus +0.18922615160210535 4.163819722996337e-15 BR00118041 PIK3CG final crispr E22 A549 96 937 OutOfFocus +0.18563524995060265 4.6244579131252474e-15 BR00118041 CA14 final crispr C19 A549 96 966 OutOfFocus +0.32786885245901637 6.603480383189088e-15 BR00118041 FFAR2 final crispr A24 A549 96 305 OutOfFocus +0.2741060025542784 6.854364354781525e-15 BR00118041 AVPR1A final crispr J07 A549 96 432 OutOfFocus +0.28744976251370113 8.119749726757743e-15 BR00118044 RPL23A final crispr G14 A549 96 391 OutOfFocus +0.20486555697823303 9.408749787661591e-15 BR00118043 OPRL1 final crispr A04 A549 96 781 OutOfFocus +0.19860270987829207 9.622283463817364e-15 BR00118041 TBXAS1 final crispr E24 A549 96 829 OutOfFocus +0.19683727957967756 1.1794629175773603e-14 BR00118041 SLCO2B1 final crispr A21 A549 96 834 OutOfFocus +0.13626518381989244 1.2409615837784475e-14 BR00118043 HSD11B1 final crispr O01 A549 96 1752 OutOfFocus +0.19542686426709788 1.4495969257084302e-14 BR00118043 CDK7 final crispr E12 A549 96 841 OutOfFocus +0.2072841163310962 1.4784989992882555e-14 BR00118041 S1PR4 final crispr L05 A549 96 745 OutOfFocus +0.20068523153942427 1.5573580807677976e-14 BR00118041 PTGIS final crispr I16 A549 96 800 OutOfFocus +0.23237067615821935 1.6417555183940735e-14 BR00118041 AKR1C1 final crispr B13 A549 96 589 OutOfFocus +0.22705207413945278 1.770643371653616e-14 BR00118041 TNNC1 final crispr D09 A549 96 618 OutOfFocus +0.18876581924901864 2.0462533882535336e-14 BR00118041 HDAC3 final crispr G07 A549 96 897 OutOfFocus +0.20971431296799734 2.1656058696924063e-14 BR00118043 KCNN4 final crispr A22 A549 96 723 OutOfFocus +0.2388688327316486 2.188791735515003e-14 BR00118041 PDE3A final crispr P18 A549 96 554 OutOfFocus +0.21731477143430827 2.4719666908813218e-14 BR00118043 HDAC3 final crispr K19 A549 96 670 OutOfFocus +0.29205467556966197 2.5898634986152296e-14 BR00118041 TUBB3 final crispr K11 A549 96 367 OutOfFocus +0.20220032166444238 3.1420105007466196e-14 BR00118043 TGM2 final crispr B09 A549 96 765 OutOfFocus +0.2049209586945436 4.539271504242556e-14 BR00118043 PARP3 final crispr F12 A549 96 740 OutOfFocus +0.3041664418909928 4.5619705296145144e-14 BR00118041 ALDH2 final crispr O09 A549 96 333 OutOfFocus +0.19557195571955718 5.215130944921215e-14 BR00118043 CA14 final crispr C19 A549 96 813 OutOfFocus +0.1447436272537761 5.2708725744270826e-14 BR00118044 S1PR2 final crispr J23 A549 96 1478 OutOfFocus +0.1878160469667319 6.111585185965729e-14 BR00118043 ITGB2 final crispr A17 A549 96 876 OutOfFocus 0.18294862361720604 1.6235241637624801e-40 BR00118041 LYN final crispr N13 A549 96 2739 Polylobed 0.15807795265434543 4.7759072826347106e-31 BR00118041 MAPK8 final crispr D07 A549 96 2807 Polylobed 0.14587882923870185 2.7605391433610837e-22 BR00118041 TUBB final crispr J17 A549 96 2352 Polylobed @@ -729,6 +7209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.14143399391464037 8.327491798056571e-19 BR00118041 CDK2 final crispr L19 A549 96 2107 Polylobed 0.14655076923916394 1.8987706708770192e-18 BR00118043 ELANE final crispr N19 A549 96 1915 Polylobed 0.15293030866885732 2.8461760441759616e-18 BR00118044 LPAR1 final crispr L01 A549 96 1740 Polylobed +0.11179428907368193 2.0851706851663374e-17 BR00118041 UGT1A9 final crispr J01 A549 96 3112 Polylobed +0.25528248141019083 9.126133800917726e-17 BR00118041 TGFBR1 final crispr P24 A549 96 569 Polylobed +0.11976045672551941 1.1305820948516865e-16 BR00118041 RGS4 final crispr N11 A549 96 2591 Polylobed +0.140011068068622 7.425764059582649e-16 BR00118044 PORCN final crispr L13 A549 96 1807 Polylobed +0.13518237888296936 8.333960853308728e-15 BR00118041 KRAS final crispr F07 A549 96 1797 Polylobed +0.13855759587785732 9.499120449476229e-15 BR00118044 AKT1 final crispr J19 A549 96 1700 Polylobed +0.1364120458503257 1.159558764316096e-14 BR00118044 LYN final crispr N13 A549 96 1748 Polylobed +0.13567771223458305 1.7999075603331686e-14 BR00118044 GJB4 final crispr N01 A549 96 1740 Polylobed +0.13942888500601835 1.8051506713963762e-14 BR00118044 AKR1B1 final crispr L21 A549 96 1649 Polylobed +0.2430450583732673 3.2463699511653685e-14 BR00118041 MMP2 final crispr E07 A549 96 527 Polylobed +0.10924841018325007 2.914526991872874e-13 BR00118041 AKR1B1 final crispr L21 A549 96 2467 Polylobed +0.23265600322235294 4.363610097656347e-13 BR00118041 HDAC3 final crispr K19 A549 96 531 Polylobed +0.25 4.961814426711253e-13 BR00118041 OPRL1 final crispr A11 A549 96 460 Polylobed +0.12618555169487586 7.292977073370215e-13 BR00118044 SLC29A1 final crispr N21 A549 96 1789 Polylobed +0.12360810690902638 7.803325379968591e-13 BR00118043 LPAR1 final crispr L01 A549 96 1855 Polylobed +0.10298883692612944 1.2053806958336418e-12 BR00118041 PTK2B final crispr N15 A549 96 2637 Polylobed +0.18413643311077146 2.098824029541801e-12 BR00118043 TGFBR1 final crispr B08 A549 96 802 Polylobed +0.12290150544960222 4.737682811063291e-12 BR00118044 GAA final crispr L17 A549 96 1765 Polylobed +0.3940969624420171 8.797272850628172e-12 BR00118041 RPL3 final crispr K04 A549 96 164 Polylobed +0.10233369913788991 1.28864516963275e-11 BR00118041 PORCN final crispr L13 A549 96 2443 Polylobed +0.3278338256879029 1.3682877148875375e-11 BR00118043 RPL23A final crispr M18 A549 96 233 Polylobed +0.13125112306603445 1.5516909168729378e-11 BR00118044 KCNQ2 final crispr P13 A549 96 1476 Polylobed +0.27523584905660375 4.216468037455238e-11 BR00118041 CDK4 final crispr B15 A549 96 318 Polylobed +0.18028721752630672 4.393414291561955e-11 BR00118041 HSD11B1 final crispr O23 A549 96 744 Polylobed +0.18382290920860345 4.529377035916165e-11 BR00118041 HRH4 final crispr A08 A549 96 715 Polylobed +0.1747710395251379 4.641867882473627e-11 BR00118043 CSK final crispr B11 A549 96 792 Polylobed +0.19558359621451105 5.11241778171032e-11 BR00118041 CHEK2 final crispr M07 A549 96 634 Polylobed +0.2963963840381898 5.44196629175762e-11 BR00118043 RPL3 final crispr K04 A549 96 269 Polylobed +0.1884234677155031 5.5321422873643725e-11 BR00118043 FFAR2 final crispr A06 A549 96 678 Polylobed +0.19655991257933006 5.869870878047165e-11 BR00118041 BTK final crispr D24 A549 96 618 Polylobed +0.16437374168751143 6.507870223022419e-11 BR00118041 SCNN1G final crispr G24 A549 96 888 Polylobed +0.22245762711864406 1.208926814924848e-10 BR00118043 TUBB3 final crispr K11 A549 96 472 Polylobed +0.20968041518710734 1.5072230124752902e-10 BR00118041 ABL1 final crispr P20 A549 96 523 Polylobed +0.1988911293298654 1.5705938720805274e-10 BR00118041 CDK7 final crispr E12 A549 96 581 Polylobed +0.15992059649462573 1.6333555157707384e-10 BR00118041 HDAC3 final crispr G07 A549 96 897 Polylobed +0.18562874251497005 1.794110397614266e-10 BR00118041 VEGFA final crispr H02 A549 96 668 Polylobed +0.1732592177708265 2.1495273931260324e-10 BR00118043 ALDH2 final crispr A10 A549 96 754 Polylobed +0.1102109758127429 3.468978072569773e-10 BR00118043 PTK2B final crispr N15 A549 96 1837 Polylobed +0.18675851122280784 4.509354615715363e-10 BR00118041 CDK7 final crispr I14 A549 96 626 Polylobed +0.11680822927067092 5.593410193742639e-10 BR00118044 OPRM1 final crispr P22 A549 96 1604 Polylobed +0.22297254150702425 5.760726812938682e-10 BR00118041 AVPR1A final crispr J07 A549 96 432 Polylobed +0.1726892970043655 5.904385523604514e-10 BR00118043 SLC7A11 final crispr P05 A549 96 728 Polylobed +0.11880426554961947 6.117635819618361e-10 BR00118044 UGT1A9 final crispr J01 A549 96 1538 Polylobed +0.18689453868606964 7.309872309345663e-10 BR00118042 HDAC3 final crispr G07 A549 96 616 Polylobed +0.220580539908271 7.491462332627135e-10 BR00118044 RPL3 final crispr K04 A549 96 441 Polylobed +0.10866716138353802 7.617780816243743e-10 BR00118044 AKR1B1 final crispr H17 A549 96 1818 Polylobed +0.11910316361451448 7.873860133226393e-10 BR00118044 HCK final crispr H23 A549 96 1515 Polylobed +0.16740250183958794 1.0426227781216747e-09 BR00118041 ATP5F1D final crispr G21 A549 96 756 Polylobed +0.1002921129503408 2.067864531621474e-09 BR00118041 F10 final crispr H15 A549 96 2054 Polylobed +0.11158521669457103 2.147191925416897e-09 BR00118044 CACNG1 final crispr N23 A549 96 1653 Polylobed +0.10125383011826233 2.3706511888456765e-09 BR00118041 PLA2G1B final crispr J11 A549 96 1998 Polylobed +0.11754379548696192 2.3892015742479477e-09 BR00118044 S1PR2 final crispr J23 A549 96 1478 Polylobed +0.11581328317528322 2.5258582172832846e-09 BR00118044 JAK1 final crispr J09 A549 96 1515 Polylobed +0.22760175938040356 2.542993753498096e-09 BR00118041 CA5A final crispr M01 A549 96 389 Polylobed +0.14538176638812675 3.0570099069847953e-09 BR00118041 GUCY1B1 final crispr N08 A549 96 946 Polylobed +0.10810854509687677 3.126678572615019e-09 BR00118044 RPL3 final crispr H11 A549 96 1726 Polylobed +0.1842866540840393 3.224560934480935e-09 BR00118041 AKR1C1 final crispr B13 A549 96 589 Polylobed +0.10661996324122813 3.98179763511554e-09 BR00118043 HSD11B1 final crispr O01 A549 96 1752 Polylobed +0.10411285094127103 4.3794668326425055e-09 BR00118043 GJB4 final crispr N01 A549 96 1829 Polylobed +0.14103075863186904 4.396638312720147e-09 BR00118043 ELANE final crispr H10 A549 96 992 Polylobed +0.16432679925597368 5.208118195168634e-09 BR00118043 KCNN4 final crispr A22 A549 96 723 Polylobed +0.10092678315188952 5.782040199733515e-09 BR00118043 S1PR2 final crispr J23 A549 96 1919 Polylobed +0.09822456289579343 5.947301008397706e-09 BR00118041 LPAR1 final crispr L01 A549 96 2026 Polylobed +0.18090452261306533 5.9736945834361835e-09 BR00118041 HIF1A final crispr M24 A549 96 597 Polylobed +0.10656926690344862 6.266352782620949e-09 BR00118044 F10 final crispr H15 A549 96 1712 Polylobed +0.1556836670838548 6.451128358981901e-09 BR00118041 CHRM3 final crispr B21 A549 96 800 Polylobed +0.10165713899825889 8.616125236044135e-09 BR00118044 TNF final crispr N17 A549 96 1845 Polylobed +0.10144664155022938 9.27199236241774e-09 BR00118043 UGT1A9 final crispr J01 A549 96 1854 Polylobed +0.10703318689922144 9.917459329047477e-09 BR00118044 BTK final crispr P17 A549 96 1662 Polylobed +0.24918032786885247 1.007151278737538e-08 BR00118041 FFAR2 final crispr A24 A549 96 305 Polylobed +0.20312432072108627 1.025269298220209e-08 BR00118041 ASIC1 final crispr M20 A549 96 453 Polylobed +0.09806734377870509 1.2412048386302153e-08 BR00118041 GJB4 final crispr N01 A549 96 1954 Polylobed +0.10515707770318121 1.400461084161694e-08 BR00118044 MET final crispr H13 A549 96 1680 Polylobed +0.1018262313226342 1.4197759042888369e-08 BR00118044 HSD11B1 final crispr O01 A549 96 1807 Polylobed +0.15712383488681758 1.6630563128327164e-08 BR00118043 KCNMA1 final crispr A07 A549 96 751 Polylobed +0.16366090922009638 1.813820823105673e-08 BR00118041 HBB final crispr M08 A549 96 681 Polylobed +0.10459790319722408 1.981492090355344e-08 BR00118043 PDPK1 final crispr N18 A549 96 1672 Polylobed +0.1570271833429728 1.988904553691488e-08 BR00118043 TUBB4B final crispr C04 A549 96 741 Polylobed +0.13999301025163094 2.103933055859819e-08 BR00118041 PTPN2 final crispr B12 A549 96 925 Polylobed +0.1551722881911561 2.9243363176510766e-08 BR00118043 PARP3 final crispr F12 A549 96 740 Polylobed +0.10753380553766903 3.085536706043007e-08 BR00118043 HCK final crispr H23 A549 96 1553 Polylobed +0.18281121334717698 3.2256106457941866e-08 BR00118043 CDK4 final crispr B15 A549 96 527 Polylobed +0.18834550361796898 3.7548884370146665e-08 BR00118042 KCNQ2 final crispr A16 A549 96 491 Polylobed +0.23993849745235798 4.0539784526593007e-08 BR00118041 CCND1 final crispr B23 A549 96 299 Polylobed +0.19690265486725664 4.455842023540605e-08 BR00118042 TGFBR1 final crispr B08 A549 96 452 Polylobed +0.18350930687662131 4.791803417141908e-08 BR00118043 OPRL1 final crispr A11 A549 96 511 Polylobed +0.21043634845242445 4.924237913416698e-08 BR00118044 RPL23A final crispr G14 A549 96 391 Polylobed +0.10310269041303524 5.635402127637802e-08 BR00118043 GAA final crispr L18 A549 96 1625 Polylobed +0.09092599655912126 6.294361267701077e-08 BR00118043 AGER final crispr J18 A549 96 2077 Polylobed +0.1556543318720969 7.032317279827041e-08 BR00118041 KCNN1 final crispr D01 A549 96 702 Polylobed 0.23028870445158167 7.093469438461008e-13 BR00118044 AURKB final crispr C13 A549 96 533 Prometaphase 0.23552423092853997 5.909933223879087e-10 BR00118041 CA5A final crispr M01 A549 96 389 Prometaphase 0.16016623911360753 2.3596320315015578e-08 BR00118044 FFAR2 final crispr A24 A549 96 703 Prometaphase @@ -739,6 +7309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2548350824587706 4.5378825361438207e-07 BR00118042 SIRT2 final crispr P01 A549 96 230 Prometaphase 0.22112211221122113 6.672149158331373e-07 BR00118044 PLK1 final crispr F13 A549 96 303 Prometaphase 0.25 8.921953501744207e-07 BR00118044 RPL23A final crispr M18 A549 96 232 Prometaphase +0.13966736207695873 1.370679553153165e-06 BR00118043 SIRT2 final crispr P01 A549 96 720 Prometaphase +0.14200543953608186 3.86993164912297e-06 BR00118044 PPAT final crispr E13 A549 96 647 Prometaphase +0.19381655550653554 4.625126107056064e-06 BR00118042 ATP5F1D final crispr E15 A549 96 339 Prometaphase +0.10286334447712903 6.902910282974739e-06 BR00118044 RNASE1 final crispr I13 A549 96 1173 Prometaphase +0.2 9.45347785936215e-06 BR00118041 FFAR2 final crispr A24 A549 96 305 Prometaphase +0.13614262560777957 2.104019410151476e-05 BR00118044 FOXM1 final crispr A19 A549 96 617 Prometaphase +0.0804417040242004 2.1671982447210847e-05 BR00118043 HSD11B1 final crispr O01 A549 96 1752 Prometaphase +0.18191333835067777 2.179141004947817e-05 BR00118042 PPAT final crispr E13 A549 96 339 Prometaphase +0.133930933436438 2.2551720808486444e-05 BR00118041 CDK7 final crispr I14 A549 96 626 Prometaphase +0.13587208988278507 2.2651935604635613e-05 BR00118043 FOXM1 final crispr A19 A549 96 612 Prometaphase +0.10740823592226248 2.2730954419845647e-05 BR00118044 SCNN1G final crispr G24 A549 96 974 Prometaphase +0.17688022284122562 2.280329181498623e-05 BR00118042 FOXM1 final crispr A19 A549 96 359 Prometaphase +0.1203585147247119 2.3921446321132833e-05 BR00118043 OPRL1 final crispr A04 A549 96 781 Prometaphase +0.13163205329153604 2.6108857843252e-05 BR00118041 PPAT final crispr G13 A549 96 640 Prometaphase +0.26535087719298245 2.7895081890787482e-05 BR00118042 AURKB final crispr C13 A549 96 152 Prometaphase +0.1271519751595653 2.9066795638713655e-05 BR00118044 S1PR1 final crispr A18 A549 96 680 Prometaphase +0.11379448646776669 4.21917259048256e-05 BR00118043 PDPK1 final crispr E16 A549 96 823 Prometaphase +0.13684662174099593 4.474817670998864e-05 BR00118044 OPRL1 final crispr A11 A549 96 564 Prometaphase +0.118508655126498 5.160550130561589e-05 BR00118043 KCNMA1 final crispr A07 A549 96 751 Prometaphase +0.13815354183008766 5.561479434167662e-05 BR00118043 CDC25A final crispr D06 A549 96 545 Prometaphase +0.19258151689323585 7.173900481425667e-05 BR00118043 RPL3 final crispr K04 A549 96 269 Prometaphase +0.1423833975181857 7.500440675318458e-05 BR00118042 COMT final crispr M02 A549 96 492 Prometaphase +0.10132094519446298 8.784817441113487e-05 BR00118043 CATSPER4 final crispr A02 A549 96 968 Prometaphase +0.1131917951536031 0.00012016487845875201 BR00118043 ALDH2 final crispr A10 A549 96 754 Prometaphase +0.12495165666340934 0.00020294780790300598 BR00118041 CDK7 final crispr E12 A549 96 581 Prometaphase +0.14786183422024066 0.00023889454005946977 BR00118041 PPAT final crispr E13 A549 96 408 Prometaphase +0.1294029107175035 0.00024073583323650768 BR00118041 HDAC3 final crispr K19 A549 96 531 Prometaphase +0.06969438942119525 0.00025674171847648566 BR00118043 GJB4 final crispr N01 A549 96 1829 Prometaphase +0.1653694968553459 0.00028055967896546967 BR00118041 CDK4 final crispr B15 A549 96 318 Prometaphase +0.12392976816234469 0.0003433402425648851 BR00118043 GRIN2A final crispr A23 A549 96 557 Prometaphase +0.13695652173913042 0.000351665210120777 BR00118041 OPRL1 final crispr A11 A549 96 460 Prometaphase +0.11326378539493294 0.00036088616435848856 BR00118043 COMT final crispr A12 A549 96 671 Prometaphase +0.0796872970588367 0.00037937016413533707 BR00118043 TGFBR1 final crispr P24 A549 96 1336 Prometaphase +0.10560625814863103 0.00038152809183604274 BR00118044 FFAR2 final crispr A06 A549 96 767 Prometaphase +0.13908045977011493 0.0003941850646587469 BR00118041 AVPR1A final crispr J07 A549 96 432 Prometaphase +0.16524628051422793 0.0004670388008532644 BR00118044 PLK1 final crispr G09 A549 96 301 Prometaphase +0.12431944493610393 0.0004742953458513571 BR00118041 CDK4 final crispr P03 A549 96 530 Prometaphase +0.10316264046833995 0.0004914028639875613 BR00118043 PTPN2 final crispr A15 A549 96 772 Prometaphase +0.09616506042288207 0.0005722693802372815 BR00118043 IGF1R final crispr E19 A549 96 877 Prometaphase +0.09195071859395415 0.0006120610752391136 BR00118043 KCNQ2 final crispr A16 A549 96 947 Prometaphase +0.10846326385469665 0.0006133467159076706 BR00118041 FOXM1 final crispr A19 A549 96 675 Prometaphase +0.11275208074723754 0.0006254771705994744 BR00118041 CSK final crispr B11 A549 96 626 Prometaphase +0.10420763847048704 0.0006341248654099123 BR00118043 GHSR final crispr A09 A549 96 726 Prometaphase +0.06999414246349296 0.0006444754228626849 BR00118043 SCNN1G final crispr P15 A549 96 1623 Prometaphase +0.1167242881052109 0.0006539213932938594 BR00118043 AURKB final crispr C13 A549 96 577 Prometaphase +0.09759186662645931 0.0006544598542406716 BR00118043 CATSPER4 final crispr P02 A549 96 834 Prometaphase +0.10741396263520157 0.0007263209713612419 BR00118043 FFAR2 final crispr A06 A549 96 678 Prometaphase +0.10798204679351528 0.0008236484707362676 BR00118044 CDK7 final crispr I14 A549 96 661 Prometaphase +0.09685301573492132 0.0008528894037344787 BR00118044 ITGB2 final crispr A17 A549 96 818 Prometaphase +0.0854126679462572 0.0009005611629136716 BR00118042 PRKCB final crispr M03 A549 96 1044 Prometaphase +0.11314475873544093 0.0009021243219887367 BR00118041 SLC7A11 final crispr P05 A549 96 601 Prometaphase +0.3354978354978355 0.0009554011773530974 BR00118041 HSD11B1 final crispr O01 A549 96 63 Prometaphase +0.17443076404115365 0.0010050379958012419 BR00118042 CA5A final crispr M01 A549 96 245 Prometaphase +0.08251070477010426 0.001010448779485164 BR00118043 KCNN1 final crispr D01 A549 96 1108 Prometaphase +0.15746400885935768 0.0010596801840847422 BR00118043 RPL23A final crispr G14 A549 96 301 Prometaphase +0.10050842327482826 0.0011679773839596496 BR00118044 GRIN2A final crispr A23 A549 96 722 Prometaphase +0.10040705563093623 0.0011774007240576978 BR00118043 S1PR1 final crispr A18 A549 96 737 Prometaphase +0.08277191540700979 0.0011978649469024934 BR00118041 IL1B final crispr H06 A549 96 1069 Prometaphase +0.2643468230318177 0.0012176280032635484 BR00118041 RPL23A final crispr M18 A549 96 103 Prometaphase +0.06955902714281982 0.0012449966171241681 BR00118044 HCK final crispr H23 A549 96 1515 Prometaphase +0.09294656029841313 0.0012720472118457403 BR00118043 CDK7 final crispr E12 A549 96 841 Prometaphase +0.05096894440702935 0.0015360628463475024 BR00118041 LYN final crispr N13 A549 96 2739 Prometaphase +0.10014946783432142 0.0015401938976743574 BR00118043 CHRM3 final crispr B17 A549 96 707 Prometaphase +0.12404055627206902 0.0016017561745275799 BR00118041 ASIC1 final crispr M20 A549 96 453 Prometaphase +0.09567701632599707 0.001684559721791089 BR00118041 CDC25A final crispr C14 A549 96 764 Prometaphase +0.08813559322033898 0.0020570972719267076 BR00118043 HIF1A final crispr A01 A549 96 885 Prometaphase +0.09652146781729906 0.002115778560802926 BR00118043 CA5A final crispr M01 A549 96 724 Prometaphase +0.08736986301369863 0.0022976786342511343 BR00118043 ITGB2 final crispr A17 A549 96 876 Prometaphase +0.13246753246753246 0.0023025198026654725 BR00118042 NAMPT final crispr D18 A549 96 385 Prometaphase +0.09133458646616541 0.0023259233412693345 BR00118043 TNNC1 final crispr D09 A549 96 798 Prometaphase +0.07485281749369217 0.002548679120771815 BR00118043 HSP90AA1 final crispr C03 A549 96 1189 Prometaphase +0.08801583443294674 0.002553814303885235 BR00118041 PRKCE final crispr K05 A549 96 847 Prometaphase +0.11864406779661017 0.002581167864302135 BR00118043 TUBB3 final crispr K11 A549 96 472 Prometaphase +0.07602087901197864 0.002669858425273754 BR00118041 AKT1 final crispr F06 A549 96 1136 Prometaphase +0.10484086423689812 0.0027737856805830838 BR00118041 AKR1C1 final crispr B13 A549 96 589 Prometaphase +0.11057606243958326 0.002786622285790501 BR00118043 CDK4 final crispr B15 A549 96 527 Prometaphase +0.09672013764948542 0.002978015713293379 BR00118044 KCNN4 final crispr A22 A549 96 685 Prometaphase +0.1072306806885366 0.0030505437960429435 BR00118041 PDE3A final crispr P18 A549 96 554 Prometaphase +0.093861072477206 0.0031767061139405333 BR00118041 CATSPER4 final crispr P02 A549 96 720 Prometaphase +0.08766367333505724 0.0031849566386722957 BR00118041 CA5A final crispr I02 A549 96 826 Prometaphase +0.2805379746835443 0.003217245421994522 BR00118042 RPL23A final crispr G14 A549 96 80 Prometaphase +0.09067515313280636 0.003540616996142605 BR00118043 TGM2 final crispr B09 A549 96 765 Prometaphase +0.07908538376099904 0.0037116027818164437 BR00118043 PPARD final crispr E05 A549 96 991 Prometaphase +0.056825479973044574 0.0038077976622811717 BR00118043 ELANE final crispr N19 A549 96 1915 Prometaphase +0.1926530001496334 0.0038172797152868153 BR00118041 RPL3 final crispr K04 A549 96 164 Prometaphase +0.08089377942319119 0.0038886140608359312 BR00118043 F10 final crispr H07 A549 96 935 Prometaphase +0.07139003197600773 0.003929695041114753 BR00118044 AURKB final crispr M05 A549 96 1210 Prometaphase +0.10670510877207859 0.004257000728160659 BR00118041 GRIN2A final crispr A23 A549 96 531 Prometaphase +0.09784398073836276 0.004588386190349163 BR00118043 ADA final crispr O24 A549 96 625 Prometaphase +0.06244446338444038 0.004637681609276596 BR00118044 UGT1A9 final crispr J01 A549 96 1538 Prometaphase 0.37837207576769377 1.4966018103499906e-34 BR00118044 AURKB final crispr C13 A549 96 533 SmallIrregular 0.1512423275756697 8.31583005545532e-28 BR00118041 LYN final crispr N13 A549 96 2739 SmallIrregular 0.17426411408584813 6.247003177394772e-26 BR00118043 ELANE final crispr N19 A549 96 1915 SmallIrregular @@ -749,6 +7409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.12890103480555085 8.839238174511919e-21 BR00118041 MAPK8 final crispr D07 A549 96 2807 SmallIrregular 0.1612527547936709 3.334853591194714e-20 BR00118044 LPAR1 final crispr L01 A549 96 1740 SmallIrregular 0.14694164272683427 5.959172523840385e-18 BR00118043 UGT1A9 final crispr J01 A549 96 1854 SmallIrregular +0.2578873988899822 1.8551695250845855e-17 BR00118043 AURKB final crispr C13 A549 96 577 SmallIrregular +0.15991666448966796 2.408194635195864e-17 BR00118044 HCK final crispr H23 A549 96 1515 SmallIrregular +0.1259489145976862 1.0129470035572939e-16 BR00118041 TUBB final crispr J17 A549 96 2352 SmallIrregular +0.1212195546276966 8.153563749864867e-16 BR00118041 CACNG1 final crispr L02 A549 96 2400 SmallIrregular +0.14572420412275633 9.198606715808567e-16 BR00118044 AKR1B1 final crispr L21 A549 96 1649 SmallIrregular +0.13951932438835174 2.4319421152415278e-15 BR00118043 HSD11B1 final crispr O01 A549 96 1752 SmallIrregular +0.21749111001695937 1.643625875982206e-14 BR00118041 FOXM1 final crispr A19 A549 96 675 SmallIrregular +0.20652173913043478 3.7915509986044815e-14 BR00118043 PPAT final crispr E13 A549 96 736 SmallIrregular +0.4402834008097166 6.19834400508906e-14 BR00118042 AURKB final crispr C13 A549 96 152 SmallIrregular +0.10902626809771293 7.040322737039735e-14 BR00118041 RGS4 final crispr N11 A549 96 2591 SmallIrregular +0.1354002334884552 1.0432125652996775e-13 BR00118044 CACNG1 final crispr N23 A549 96 1653 SmallIrregular +0.12862789605278513 1.1157454811047507e-13 BR00118043 PTK2B final crispr N15 A549 96 1837 SmallIrregular +0.14179863219105437 2.046693896073623e-13 BR00118044 S1PR2 final crispr J23 A549 96 1478 SmallIrregular +0.13779781068898905 2.867859569185801e-13 BR00118043 HCK final crispr H23 A549 96 1553 SmallIrregular +0.1283364345381844 5.671422945949141e-13 BR00118044 GJB4 final crispr N01 A549 96 1740 SmallIrregular +0.1266490205202773 5.863009950724291e-13 BR00118044 SLC29A1 final crispr N21 A549 96 1789 SmallIrregular +0.30363036303630364 9.926373700062868e-13 BR00118044 PLK1 final crispr F13 A549 96 303 SmallIrregular +0.13418845842367877 2.512004165475548e-12 BR00118044 JAK1 final crispr J09 A549 96 1515 SmallIrregular +0.09354537907608808 2.6435806959857397e-12 BR00118041 UGT1A9 final crispr J01 A549 96 3112 SmallIrregular +0.1111839620673989 8.04258943319523e-12 BR00118041 CDK2 final crispr L19 A549 96 2107 SmallIrregular +0.11953514111787493 1.1587539524797196e-11 BR00118044 HSD11B1 final crispr O01 A549 96 1807 SmallIrregular +0.12871372768092595 1.42635322710217e-11 BR00118044 UGT1A9 final crispr J01 A549 96 1538 SmallIrregular +0.12089091772611482 1.456047723343943e-11 BR00118044 LYN final crispr N13 A549 96 1748 SmallIrregular +0.1947569581730827 3.591965220048242e-11 BR00118044 PPAT final crispr E13 A549 96 647 SmallIrregular +0.11510791366906475 7.634295511792588e-11 BR00118044 PORCN final crispr L13 A549 96 1807 SmallIrregular +0.5330696202531645 9.310851584397705e-11 BR00118042 RPL23A final crispr G14 A549 96 80 SmallIrregular +0.20426287744227353 1.0875489875516964e-10 BR00118042 PPAT final crispr G13 A549 96 563 SmallIrregular +0.1199727559975172 1.1229774345459451e-10 BR00118043 SCNN1G final crispr P15 A549 96 1623 SmallIrregular +0.30052371160519215 1.769037220307365e-10 BR00118043 PLK1 final crispr G09 A549 96 251 SmallIrregular +0.25562504865959046 3.0737567144063277e-10 BR00118042 PPAT final crispr E13 A549 96 339 SmallIrregular +0.3078335832083958 3.0937371282828584e-10 BR00118042 SIRT2 final crispr P01 A549 96 230 SmallIrregular +0.17805910615148796 5.916969038985318e-10 BR00118043 S1PR1 final crispr P23 A549 96 682 SmallIrregular +0.14407871821664925 6.354334052706931e-10 BR00118043 MAPK8 final crispr D07 A549 96 1045 SmallIrregular +0.2649362770697452 8.719534188017483e-10 BR00118044 PLK1 final crispr G09 A549 96 301 SmallIrregular +0.08893759440241496 8.963015394988807e-10 BR00118041 AGER final crispr J18 A549 96 2707 SmallIrregular +0.12153662451399765 1.037892448266796e-09 BR00118043 BTK final crispr P17 A549 96 1434 SmallIrregular +0.14868473046071828 1.2148146368144605e-09 BR00118041 GUCY1B1 final crispr N08 A549 96 946 SmallIrregular +0.1183968301117382 1.8150917646493886e-09 BR00118044 KCNQ2 final crispr P13 A549 96 1476 SmallIrregular +0.10475414504957617 2.9887811854186935e-09 BR00118044 TNF final crispr N17 A549 96 1845 SmallIrregular +0.4643416927899687 3.0260288704287044e-09 BR00118042 PLK1 final crispr G09 A549 96 87 SmallIrregular +0.11201267599271653 3.2078040309087766e-09 BR00118044 OPRM1 final crispr P22 A549 96 1604 SmallIrregular +0.1093725883624016 3.5647448023766244e-09 BR00118043 PDPK1 final crispr N18 A549 96 1672 SmallIrregular +0.08371072398437152 4.1050719249502264e-09 BR00118041 FOXM1 final crispr F23 A549 96 2840 SmallIrregular +0.11118508655126498 1.6714470809418852e-08 BR00118043 OPRM1 final crispr P22 A549 96 1502 SmallIrregular +0.09804248472314543 1.7502850036305486e-08 BR00118043 S1PR2 final crispr J23 A549 96 1919 SmallIrregular +0.12412152476722857 2.2065397796762598e-08 BR00118044 LPAR1 final crispr B16 A549 96 1174 SmallIrregular +0.08576571128506678 2.412670004520237e-08 BR00118041 AKR1B1 final crispr L21 A549 96 2467 SmallIrregular +0.2574626865671642 3.259229385690615e-08 BR00118042 CDK7 final crispr I14 A549 96 268 SmallIrregular +0.09435846230654019 3.518345818124201e-08 BR00118041 EZH2 final crispr H09 A549 96 2003 SmallIrregular +0.09999148374117643 3.783573603507787e-08 BR00118044 GAA final crispr L17 A549 96 1765 SmallIrregular +0.21105332710931696 3.863566500602779e-08 BR00118041 CA5A final crispr M01 A549 96 389 SmallIrregular +0.168030573110787 5.502707013510642e-08 BR00118043 FOXM1 final crispr A19 A549 96 612 SmallIrregular +0.2710737045500994 5.5564514323775206e-08 BR00118043 RPL23A final crispr M18 A549 96 233 SmallIrregular +0.21445788543881186 7.544086945789163e-08 BR00118041 TUBB3 final crispr K11 A549 96 367 SmallIrregular +0.0958226663787874 1.0464712390995412e-07 BR00118044 AKR1B1 final crispr H17 A549 96 1818 SmallIrregular +0.1054739652870494 1.1285250218307004e-07 BR00118043 F10 final crispr H15 A549 96 1498 SmallIrregular +0.10371819960861056 1.3441483004439715e-07 BR00118043 CACNG1 final crispr L02 A549 96 1533 SmallIrregular +0.10013035240621447 1.4027390317927002e-07 BR00118043 GAA final crispr L18 A549 96 1625 SmallIrregular +0.09781234166451436 1.6900644849772528e-07 BR00118043 CACNG1 final crispr N23 A549 96 1684 SmallIrregular +0.2307641196013289 1.8385840868425233e-07 BR00118043 RPL23A final crispr G14 A549 96 301 SmallIrregular +0.2629310344827586 1.8554117092510505e-07 BR00118044 RPL23A final crispr M18 A549 96 232 SmallIrregular +0.09717146823036174 2.4172631996174177e-07 BR00118044 MET final crispr H13 A549 96 1680 SmallIrregular +0.2388098602175613 2.835506589782627e-07 BR00118043 RPL3 final crispr K04 A549 96 269 SmallIrregular +0.10355190259093944 2.940354151774802e-07 BR00118044 S1PR1 final crispr P23 A549 96 1461 SmallIrregular +0.1289418498679463 3.196566519413486e-07 BR00118044 CLK1 final crispr M11 A549 96 927 SmallIrregular +0.07975108548526025 3.2940830930565056e-07 BR00118041 PORCN final crispr L13 A549 96 2443 SmallIrregular +0.15883306320907617 3.294497858621197e-07 BR00118044 FOXM1 final crispr A19 A549 96 617 SmallIrregular +0.10643015521064302 4.3142754299180403e-07 BR00118044 AVPR1A final crispr J07 A549 96 1353 SmallIrregular +0.11838612845962254 4.676129439397313e-07 BR00118041 GPR119 final crispr G23 A549 96 1084 SmallIrregular +0.094285368468375 5.157753834060479e-07 BR00118044 AKT1 final crispr J19 A549 96 1700 SmallIrregular +0.10404276699658556 6.886857203723689e-07 BR00118043 KCNQ2 final crispr P13 A549 96 1360 SmallIrregular +0.14982856583072102 1.0249144180986877e-06 BR00118041 PPAT final crispr G13 A549 96 640 SmallIrregular +0.08430867085194249 1.2388653324957438e-06 BR00118041 PLA2G1B final crispr J11 A549 96 1998 SmallIrregular +0.09550841627698389 1.6872533907542028e-06 BR00118043 NTRK1 final crispr P07 A549 96 1516 SmallIrregular +0.2647320931268798 2.418477893630559e-06 BR00118042 CDK2 final crispr F08 A549 96 188 SmallIrregular +0.2287377450980392 2.5058026184891757e-06 BR00118041 AURKB final crispr C13 A549 96 255 SmallIrregular +0.10698878343399482 3.395248799207141e-06 BR00118041 MET final crispr E20 A549 96 1159 SmallIrregular +0.09714285714285714 3.6006384641072565e-06 BR00118041 PDE3A final crispr O08 A549 96 1400 SmallIrregular +0.1145724883199833 3.7659761357817207e-06 BR00118043 CYP3A4 final crispr D04 A549 96 998 SmallIrregular +0.12010959570754284 3.925371123011512e-06 BR00118041 HDAC3 final crispr G07 A549 96 897 SmallIrregular +0.08534919000115262 3.958777264217038e-06 BR00118044 GUCY1B1 final crispr H21 A549 96 1796 SmallIrregular +0.10911922943422422 5.000941490080265e-06 BR00118041 CATSPER4 final crispr A02 A549 96 1072 SmallIrregular +0.14858829035747606 5.8013753784626124e-06 BR00118041 TGFBR1 final crispr P24 A549 96 569 SmallIrregular +0.09229171807849364 7.1458918247053595e-06 BR00118043 HRH4 final crispr H24 A549 96 1465 SmallIrregular +0.1105275596754287 7.3559818331872655e-06 BR00118041 MET final crispr H13 A549 96 1011 SmallIrregular +0.21446333564654174 8.090074754639252e-06 BR00118042 TUBB3 final crispr K11 A549 96 262 SmallIrregular +0.1755376063468866 8.369121974907765e-06 BR00118044 RPL23A final crispr G14 A549 96 391 SmallIrregular +0.10781483379009545 8.498506402200376e-06 BR00118041 CCR1 final crispr G02 A549 96 1053 SmallIrregular +0.1167964404894327 9.242950245598842e-06 BR00118041 CCR1 final crispr O17 A549 96 899 SmallIrregular +0.08255211288919154 9.745972697579994e-06 BR00118041 BTK final crispr P17 A549 96 1782 SmallIrregular 0.17384854596722793 4.518569278498114e-33 BR00117005 LPAR1 final crispr L01 A549 144 2470 ADCCM 0.15462158156323494 5.008793389386448e-29 BR00117003 PORCN final crispr L13 A549 144 2737 ADCCM 0.15300080023370938 7.004869763667577e-24 BR00117001 CACNA2D3 final crispr O07 A549 144 2289 ADCCM @@ -759,6 +7509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.11726865335274947 1.1350590523650071e-18 BR00117003 TUBB4B final crispr J13 A549 144 3036 ADCCM 0.3290524373720776 1.7301456158319254e-18 BR00117000 RPL3 final crispr K04 A549 144 372 ADCCM 0.48443775100401604 3.2440875290031394e-18 BR00117000 RPL23A final crispr M18 A549 144 166 ADCCM +0.12369902387660434 4.0694519357232615e-18 BR00117003 CACNG1 final crispr N23 A549 144 2650 ADCCM +0.2484375 9.51842065035772e-18 BR00117004 TUBB4B final crispr C04 A549 144 640 ADCCM +0.11541273414568338 1.146511902761805e-17 BR00117004 PORCN final crispr L13 A549 144 2968 ADCCM +0.23226717327436752 5.598643387851088e-17 BR00117004 HDAC3 final crispr K19 A549 144 693 ADCCM +0.12140288840950116 1.767707330836103e-16 BR00117005 PTK2B final crispr N15 A549 144 2494 ADCCM +0.2593320235756385 1.8973799392033022e-15 BR00117000 TUBB3 final crispr K11 A549 144 509 ADCCM +0.13997645690246516 2.348530829201022e-15 BR00117001 LPAR1 final crispr L01 A549 144 1739 ADCCM +0.12433707152487664 3.0032309558992603e-15 BR00117005 ELANE final crispr N19 A549 144 2192 ADCCM +0.3901630988786952 3.0523838043888555e-15 BR00117004 SIRT2 final crispr P01 A549 144 218 ADCCM +0.12356932254795293 4.161093255069762e-15 BR00117003 HSP90AB1 final crispr B04 A549 144 2198 ADCCM +0.33344479291578266 5.410814619394205e-15 BR00117000 PLK1 final crispr G09 A549 144 293 ADCCM +0.2639643844140632 9.326585596166004e-15 BR00117004 S1PR1 final crispr A18 A549 144 467 ADCCM +0.10037947490592425 1.2624176568252826e-14 BR00117004 AKT1 final crispr J19 A549 144 3225 ADCCM +0.11896523710261633 2.6877318164342466e-14 BR00117003 PDE3A final crispr O08 A549 144 2248 ADCCM +0.13393266472805487 4.4669196308818256e-14 BR00117001 CACNG1 final crispr N23 A549 144 1738 ADCCM +0.10158992957006202 4.9178734985972525e-14 BR00117004 AKR1B1 final crispr L21 A549 144 3024 ADCCM +0.20459231766230707 5.935341502285025e-14 BR00117004 GHSR final crispr B20 A549 144 738 ADCCM +0.12077067669172932 6.188699640078471e-14 BR00117003 HCK final crispr H23 A549 144 2128 ADCCM +0.18761837639679171 8.309666688474097e-14 BR00117004 BRAF final crispr F20 A549 144 869 ADCCM +0.10712203539049847 8.692300518852398e-14 BR00117004 AGER final crispr J18 A549 144 2673 ADCCM +0.30351579884290164 1.0930383622017865e-13 BR00117004 CDK9 final crispr I20 A549 144 322 ADCCM +0.19698031805374946 1.7790065405269243e-13 BR00117000 NAMPT final crispr I09 A549 144 768 ADCCM +0.12080442129982205 1.9756547499419042e-13 BR00117003 LYN final crispr N13 A549 144 2038 ADCCM +0.3033414374409773 2.2046298791760318e-13 BR00117004 GRIN2A final crispr A23 A549 144 314 ADCCM +0.11331285656318105 2.9161795167744267e-13 BR00117005 PDPK1 final crispr N18 A549 144 2282 ADCCM +0.19421933998205185 3.832419214397619e-13 BR00117004 KCNMA1 final crispr E23 A549 144 770 ADCCM +0.1817990087525045 4.2933269885319293e-13 BR00117000 DHH final crispr F05 A549 144 872 ADCCM +0.1995792992162287 4.5448632566383366e-13 BR00117003 SLC29A1 final crispr E03 A549 144 723 ADCCM +0.17080284343584906 4.877415543585425e-13 BR00117004 PNLIP final crispr C18 A549 144 989 ADCCM +0.21750681892775897 8.626198709678207e-13 BR00117005 BTK final crispr D24 A549 144 593 ADCCM +0.15942028985507245 1.1723285946801108e-12 BR00117000 AKT1 final crispr F06 A549 144 1104 ADCCM +0.24319955791945846 1.204147830361852e-12 BR00117005 SLC7A11 final crispr P05 A549 144 465 ADCCM +0.30582913421896474 1.2198598625604758e-12 BR00117001 RPL3 final crispr K04 A549 144 296 ADCCM +0.2105387913265727 1.2437765701098914e-12 BR00117004 ATP5F1D final crispr G21 A549 144 622 ADCCM +0.2134646962233169 1.4657610113460202e-12 BR00117004 PTPN2 final crispr B12 A549 144 609 ADCCM +0.24123474412320509 1.629636769217142e-12 BR00117005 UGT1A9 final crispr B18 A549 144 473 ADCCM +0.20552147239263804 1.8379116976871424e-12 BR00117000 IMPDH1 final crispr F15 A549 144 652 ADCCM +0.2785882699675803 1.9816909601669815e-12 BR00117004 KCNN1 final crispr D01 A549 144 351 ADCCM +0.2381987017670393 2.7750408086752755e-12 BR00117004 SSTR2 final crispr P10 A549 144 470 ADCCM +0.2728274363749224 3.0340220155362395e-12 BR00117000 RPL23A final crispr G14 A549 144 358 ADCCM +0.10089860745714031 3.7176964101476475e-12 BR00117004 MAPK8 final crispr D13 A549 144 2632 ADCCM +0.3248426435877262 3.867650777833572e-12 BR00117004 CDK9 final crispr M04 A549 144 246 ADCCM +0.16506706697012252 5.618653578272866e-12 BR00117000 TUBB final crispr K13 A549 144 963 ADCCM +0.2913291329132913 5.930982910054661e-12 BR00117002 HDAC3 final crispr K19 A549 144 303 ADCCM +0.26167141341374883 6.635601963207346e-12 BR00117004 SLC7A11 final crispr P05 A549 144 376 ADCCM +0.10622271526949804 6.977232395999277e-12 BR00117003 GAA final crispr L17 A549 144 2330 ADCCM +0.2085105550009368 7.560575512935002e-12 BR00117004 IGF1R final crispr E19 A549 144 599 ADCCM +0.26721763085399447 8.35975235441622e-12 BR00117004 FOXM1 final crispr A19 A549 144 363 ADCCM +0.16613756613756614 8.44203733253591e-12 BR00117000 ATP5F1D final crispr G21 A549 144 945 ADCCM +0.19285714285714287 8.529676350731563e-12 BR00117005 MMP2 final crispr E07 A549 144 700 ADCCM +0.1038468456937675 8.895022613610887e-12 BR00117004 KRAS final crispr D21 A549 144 2404 ADCCM +0.17783191230207065 9.376095907922735e-12 BR00117004 CDK7 final crispr E12 A549 144 821 ADCCM +0.18703221333133443 1.0166403212238927e-11 BR00117000 HPGDS final crispr B19 A549 144 731 ADCCM +0.11602781831707035 1.0214979896914188e-11 BR00117000 LPAR1 final crispr L01 A549 144 1916 ADCCM +0.17718446601941748 1.0320098510456217e-11 BR00117003 TUBB4B final crispr C04 A549 144 824 ADCCM +0.16287400663944174 1.2075533262410606e-11 BR00117000 ATP5F1D final crispr E15 A549 144 963 ADCCM +0.1843193033175018 1.3331278066100662e-11 BR00117005 PDE4D final crispr P06 A549 144 751 ADCCM +0.19875744201889756 1.700708176494775e-11 BR00117000 FFAR2 final crispr A24 A549 144 636 ADCCM +0.18111254851228978 1.719484788102208e-11 BR00117000 IGF1R final crispr E19 A549 144 773 ADCCM +0.15153028774271318 1.8496786090025162e-11 BR00117000 MMP2 final crispr D14 A549 144 1094 ADCCM +0.22373289493157972 1.9804356307548297e-11 BR00117005 IGF1R final crispr E19 A549 144 501 ADCCM +0.22463039158290524 2.060088121943211e-11 BR00117004 OPRL1 final crispr A11 A549 144 491 ADCCM +0.18214686248331108 2.2994819446137278e-11 BR00117000 CDK7 final crispr I14 A549 144 749 ADCCM +0.22602105551935806 2.3089492950750732e-11 BR00117003 FFAR2 final crispr A24 A549 144 482 ADCCM +0.1027101110867695 2.5966693508182254e-11 BR00117003 IL1B final crispr H18 A549 144 2370 ADCCM +0.19758005685105526 2.616762540813772e-11 BR00117000 CYP2A6 final crispr C07 A549 144 631 ADCCM +0.10403131959131416 3.0660167892196653e-11 BR00117003 LPAR1 final crispr L01 A549 144 2283 ADCCM +0.2006738768718802 4.501155978546057e-11 BR00117000 CHRM3 final crispr B21 A549 144 600 ADCCM +0.09688581314878893 4.819798305237165e-11 BR00117004 F10 final crispr H15 A549 144 2601 ADCCM +0.18321053780991023 4.9198904486990575e-11 BR00117000 CTSG final crispr L12 A549 144 722 ADCCM +0.10271196360135174 5.061691569952869e-11 BR00117003 CHRM3 final crispr B17 A549 144 2300 ADCCM +0.179628532974428 5.195790285612083e-11 BR00117004 HSP90AA1 final crispr I04 A549 144 750 ADCCM +0.10715751947609002 5.36484712372193e-11 BR00117005 AKR1B1 final crispr L21 A549 144 2107 ADCCM +0.20994028932811132 5.3999593322868554e-11 BR00117001 SLC7A11 final crispr P05 A549 144 541 ADCCM +0.16449097599439286 6.905395991968953e-11 BR00117004 PRKCE final crispr I17 A549 144 878 ADCCM +0.23394495412844038 7.133077132620253e-11 BR00117004 DYRK1B final crispr N16 A549 144 436 ADCCM +0.2099696250387804 1.0768863338302364e-10 BR00117004 TUBB final crispr K13 A549 144 526 ADCCM +0.10843289860375978 1.0815337655227562e-10 BR00117000 LYN final crispr N13 A549 144 1995 ADCCM +0.20955991674100505 1.175565949945398e-10 BR00117005 HDAC3 final crispr G07 A549 144 532 ADCCM +0.17896174863387979 1.1788090591213303e-10 BR00117004 COMT final crispr A12 A549 144 732 ADCCM +0.18867778039270872 1.635699124105787e-10 BR00117000 COMT final crispr A12 A549 144 643 ADCCM +0.19055118110236222 1.7146185866425836e-10 BR00117004 ABL1 final crispr C01 A549 144 635 ADCCM +0.28889474560284084 1.833436369183534e-10 BR00117001 RPL23A final crispr M18 A549 144 269 ADCCM +0.15525062220675998 1.9254306590226144e-10 BR00117000 PIK3CG final crispr E22 A549 144 946 ADCCM +0.1899335666108829 2.0924996573899721e-10 BR00117004 KCNN1 final crispr B24 A549 144 626 ADCCM +0.17591777074002585 2.3067775530626168e-10 BR00117000 TGFBR1 final crispr B08 A549 144 731 ADCCM +0.15062977878358694 2.4338930989596255e-10 BR00117004 MET final crispr E20 A549 144 995 ADCCM +0.2404204043379301 2.5110707947689697e-10 BR00117003 CDK9 final crispr I20 A549 144 388 ADCCM +0.1521742328709542 2.6497165926785977e-10 BR00117004 ATM final crispr F14 A549 144 976 ADCCM +0.25811706038656135 2.8330736536349834e-10 BR00117002 VEGFA final crispr C24 A549 144 331 ADCCM 0.43386151592258465 7.307184235921331e-34 BR00117000 AURKB final crispr C13 A549 144 396 Anaphase 0.4682109583986717 8.380149293503888e-30 BR00117000 PLK1 final crispr G09 A549 144 293 Anaphase 0.6308108108108108 2.641865574253682e-28 BR00117005 AURKB final crispr C13 A549 144 150 Anaphase @@ -769,6 +7609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5397303499713139 4.795316308317577e-23 BR00117000 RPL23A final crispr M18 A549 144 166 Anaphase 0.4788056405028882 5.745484592938903e-23 BR00117004 SIRT2 final crispr P01 A549 144 218 Anaphase 0.3102886616595783 2.349459908203775e-22 BR00117000 CDK4 final crispr B15 A549 144 516 Anaphase +0.33715596330275227 2.3723931169528645e-22 BR00117004 CDK7 final crispr I14 A549 144 436 Anaphase +0.36572004965859717 5.661589497207481e-22 BR00117000 RPL23A final crispr G14 A549 144 358 Anaphase +0.29381449956731204 1.0484015940636771e-21 BR00117003 FOXM1 final crispr A19 A549 144 557 Anaphase +0.5076399589111453 1.7206622702228923e-21 BR00117004 AURKB final crispr C13 A549 144 176 Anaphase +0.2573195012503293 2.729362517448342e-20 BR00117001 AURKB final crispr C13 A549 144 682 Anaphase +0.4482263422998607 5.4141530508495284e-20 BR00117000 PLK1 final crispr F13 A549 144 217 Anaphase +0.3497781721384206 2.790586373568345e-19 BR00117001 PLK1 final crispr G09 A549 144 345 Anaphase +0.31938978937332063 3.2319582364072084e-19 BR00117003 CDK2 final crispr F08 A549 144 415 Anaphase +0.37524908953480385 4.050880010524337e-19 BR00117004 CA5A final crispr M01 A549 144 294 Anaphase +0.49797979797979797 6.484045362247293e-19 BR00117003 TUBB3 final crispr K11 A549 144 162 Anaphase +0.29219055985651277 3.2042666738702554e-18 BR00117004 S1PR1 final crispr A18 A549 144 467 Anaphase +0.2964986233278916 4.023816375283068e-18 BR00117001 TUBB3 final crispr K11 A549 144 455 Anaphase +0.26650829427527734 1.6750510657300876e-17 BR00117001 SLC7A11 final crispr P05 A549 144 541 Anaphase +0.29723502304147464 2.5972117569798296e-17 BR00117004 CDK2 final crispr F08 A549 144 434 Anaphase +0.27746823069403714 2.7997510204065877e-17 BR00117003 PRKCE final crispr K05 A549 144 495 Anaphase +0.31188244744945776 3.818319316647823e-17 BR00117003 CDK9 final crispr I20 A549 144 388 Anaphase +0.32404828226555243 4.3441399923999585e-17 BR00117003 CDK4 final crispr P03 A549 144 354 Anaphase +0.3704155800921045 7.605499831463909e-17 BR00117001 RPL23A final crispr M18 A549 144 269 Anaphase +0.26981464460784316 8.032657440079886e-17 BR00117000 FOXM1 final crispr A19 A549 144 512 Anaphase +0.31955922865013775 8.704605727016094e-17 BR00117004 FOXM1 final crispr A19 A549 144 363 Anaphase +0.37047715965626415 8.77846002556905e-17 BR00117004 RPL23A final crispr G14 A549 144 268 Anaphase +0.2601144459989856 1.299673315673588e-16 BR00117003 FPR1 final crispr N22 A549 144 541 Anaphase +0.4540229885057471 1.5450879542917198e-16 BR00117005 TUBB3 final crispr K11 A549 144 174 Anaphase +0.7872733999260081 2.454329956028117e-16 BR00117002 RPL23A final crispr M18 A549 144 51 Anaphase +0.3079649122807018 2.566034664643979e-16 BR00117004 PPAT final crispr E13 A549 144 375 Anaphase +0.37614976033164915 3.927898234782111e-16 BR00117004 TUBB3 final crispr K11 A549 144 248 Anaphase +0.2168811748998665 5.480144282093274e-16 BR00117000 CDK7 final crispr I14 A549 144 749 Anaphase +0.3727380015735641 7.391707714943944e-16 BR00117004 CDK9 final crispr M04 A549 144 246 Anaphase +0.265338852379264 8.414730313823522e-16 BR00117004 CDC25A final crispr D06 A549 144 491 Anaphase +0.5179504132231405 1.4334400587655061e-15 BR00117003 RPL23A final crispr G14 A549 144 125 Anaphase +0.5812865497076023 4.464529334163559e-15 BR00117002 TUBB3 final crispr K11 A549 144 95 Anaphase +0.29426579938763703 6.5070826961849475e-15 BR00117001 RPL23A final crispr G14 A549 144 379 Anaphase +0.31950611826639075 8.03576886674103e-15 BR00117004 GRIN2A final crispr A23 A549 144 314 Anaphase +0.32368951180832367 1.0575144567014271e-14 BR00117002 HDAC3 final crispr K19 A549 144 303 Anaphase +0.26420101637492943 1.3170938194790396e-14 BR00117005 CDK7 final crispr E12 A549 144 460 Anaphase +0.32409076104657475 1.3717674726873865e-14 BR00117004 CDK4 final crispr P03 A549 144 302 Anaphase +0.2755850324374421 2.1014951700105842e-14 BR00117004 CTSG final crispr L12 A549 144 416 Anaphase +0.2122022103970528 2.583235259955673e-14 BR00117001 PPAT final crispr E13 A549 144 698 Anaphase +0.20046107849140882 2.695598592727465e-14 BR00117001 AVPR1A final crispr J07 A549 144 781 Anaphase +0.2637931763412675 8.96368151754902e-14 BR00117001 CDK4 final crispr B15 A549 144 436 Anaphase +0.24889407084805049 1.0484284935685357e-13 BR00117003 FFAR2 final crispr A24 A549 144 482 Anaphase +0.097149709001956 1.1178382150451223e-13 BR00117004 AKT1 final crispr J19 A549 144 3225 Anaphase +0.40325652256713007 1.4189217722977677e-13 BR00117003 SIRT2 final crispr P01 A549 144 178 Anaphase +0.20229377024195086 1.629739018441189e-13 BR00117000 CDK7 final crispr E12 A549 144 724 Anaphase +0.3158268437929455 1.7870951483509384e-13 BR00117001 RPL3 final crispr K04 A549 144 296 Anaphase +0.6787878787878788 3.496330812288568e-13 BR00117005 PLK1 final crispr G09 A549 144 55 Anaphase +0.27745367192862047 3.6007848365610613e-13 BR00117004 CDK4 final crispr B15 A549 144 372 Anaphase +0.5632183908045977 4.642834791529173e-13 BR00117003 RPL3 final crispr K04 A549 144 87 Anaphase +0.24458965209634256 5.641821883650916e-13 BR00117004 ASIC1 final crispr M20 A549 144 472 Anaphase +0.18131393019086786 5.651805050121935e-13 BR00117000 DHH final crispr F05 A549 144 872 Anaphase +0.26194884576582994 6.359426966564849e-13 BR00117003 SLC7A11 final crispr P05 A549 144 411 Anaphase +0.2934364027636199 7.053468712339e-13 BR00117003 ATP5F1D final crispr E15 A549 144 327 Anaphase +0.46153846153846156 7.213091449808737e-13 BR00117005 RPL23A final crispr G14 A549 144 130 Anaphase +0.32495527728085866 1.0532020534091891e-12 BR00117002 PPAT final crispr E13 A549 144 258 Anaphase +0.26515151515151514 1.2019123572657845e-12 BR00117005 HRH4 final crispr A08 A549 144 396 Anaphase +0.2571428571428571 1.313204396677366e-12 BR00117004 HRH4 final crispr A08 A549 144 420 Anaphase +0.30691320645905423 1.415802157960252e-12 BR00117005 PPAT final crispr E13 A549 144 288 Anaphase +0.2414257137661393 1.4755391751390923e-12 BR00117003 PARP3 final crispr L11 A549 144 470 Anaphase +0.2543724020481104 1.7477026425308335e-12 BR00117003 CACNA2D3 final crispr O07 A549 144 422 Anaphase +0.23497447990962836 1.8302623155103494e-12 BR00117004 OPRL1 final crispr A11 A549 144 491 Anaphase +0.23010267324648595 2.662693602323469e-12 BR00117003 KCNN1 final crispr D01 A549 144 507 Anaphase +0.20913618132385797 3.902152631257805e-12 BR00117003 RGS4 final crispr N11 A549 144 609 Anaphase +0.1716426193118757 4.140273188359291e-12 BR00117004 MME final crispr H08 A549 144 901 Anaphase +0.2723478123643824 4.143861546796046e-12 BR00117004 PPAT final crispr G13 A549 144 357 Anaphase +0.22941022716471818 4.545227170973697e-12 BR00117004 KCNN4 final crispr K01 A549 144 504 Anaphase +0.18088612452092462 4.585811463248559e-12 BR00117004 TNNC1 final crispr D09 A549 144 811 Anaphase +0.10315757416354047 5.339902635870323e-12 BR00117005 PTK2B final crispr N15 A549 144 2494 Anaphase +0.278248127645718 7.292993283659448e-12 BR00117005 TUBB4B final crispr C04 A549 144 332 Anaphase +0.10854965137394197 9.805762938066601e-12 BR00117004 GUCY1B1 final crispr H21 A549 144 2199 Anaphase +0.1872548095946939 1.2150250966468487e-11 BR00117004 CYP3A4 final crispr D04 A549 144 727 Anaphase +0.2861736334405145 1.2652264334209264e-11 BR00117005 HDAC3 final crispr K19 A549 144 311 Anaphase +0.19658972233539862 1.634799378142762e-11 BR00117003 BRD4 final crispr M19 A549 144 653 Anaphase +0.11721694209991253 1.646262616087233e-11 BR00117004 S1PR2 final crispr J23 A549 144 1840 Anaphase +0.2928494092171539 1.8379685701554426e-11 BR00117002 FOXM1 final crispr A19 A549 144 292 Anaphase +0.25692582663092045 2.160994746572371e-11 BR00117000 RPL3 final crispr K04 A549 144 372 Anaphase +0.37226762341372666 2.3502848384197134e-11 BR00117002 CDK7 final crispr E12 A549 144 173 Anaphase +0.21979685971206261 2.811073866620339e-11 BR00117003 CA5A final crispr M01 A549 144 508 Anaphase +0.21498147646155236 3.610338164912403e-11 BR00117003 ABL1 final crispr P20 A549 144 527 Anaphase +0.4535232383808096 3.9024310607189406e-11 BR00117002 AURKB final crispr C13 A549 144 115 Anaphase +0.1743074915753804 4.445447197067618e-11 BR00117003 CDK7 final crispr E12 A549 144 798 Anaphase +0.18181818181818182 6.71518999656462e-11 BR00117000 AGER final crispr K20 A549 144 726 Anaphase +0.20583353783759348 7.564777334717805e-11 BR00117003 PORCN final crispr N07 A549 144 557 Anaphase +0.15762235613070347 8.471841249125969e-11 BR00117003 PPAT final crispr G13 A549 144 954 Anaphase +0.24676004623648604 8.80904246255696e-11 BR00117003 CLK1 final crispr M11 A549 144 385 Anaphase +0.19751100318713005 9.16093916290583e-11 BR00117004 BRD4 final crispr J16 A549 144 605 Anaphase +0.16930572472594396 1.0901330426978276e-10 BR00117004 CDK7 final crispr E12 A549 144 821 Anaphase +0.22394853573004483 1.1396156582737762e-10 BR00117000 CASP3 final crispr D19 A549 144 465 Anaphase +0.25535205535205535 1.5163115392447123e-10 BR00117005 DHH final crispr F05 A549 144 350 Anaphase +0.17838289534347626 1.5467052163213233e-10 BR00117003 SLC29A1 final crispr E03 A549 144 723 Anaphase +0.2658714034171165 1.772130728476178e-10 BR00117004 CDK9 final crispr I20 A549 144 322 Anaphase 0.2196589357613632 3.6822027864982725e-53 BR00117005 PTK2B final crispr N15 A549 144 2494 Apoptosis 0.1917706425986534 2.0930799514225537e-52 BR00117004 AKT1 final crispr J19 A549 144 3225 Apoptosis 0.20181014750867143 1.412494521802062e-44 BR00117005 LPAR1 final crispr L01 A549 144 2470 Apoptosis @@ -779,6 +7709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.16563328691073506 4.990180986991482e-36 BR00117004 PORCN final crispr L13 A549 144 2968 Apoptosis 0.4551875234224106 1.596527672534826e-35 BR00117000 RPL3 final crispr K04 A549 144 372 Apoptosis 0.3665295833093973 4.5712087239396e-33 BR00117001 SLC7A11 final crispr P05 A549 144 541 Apoptosis +0.4769635717012598 5.328219284553978e-33 BR00117004 GRIN2A final crispr A23 A549 144 314 Apoptosis +0.16712797746094082 7.928951127820044e-33 BR00117003 CACNG1 final crispr N23 A549 144 2650 Apoptosis +0.6285857716580608 2.172695808971614e-31 BR00117000 RPL23A final crispr M18 A549 144 166 Apoptosis +0.5538990825688074 2.178515759662945e-31 BR00117004 SIRT2 final crispr P01 A549 144 218 Apoptosis +0.5169873040549294 9.940116955666395e-31 BR00117004 TUBB3 final crispr K11 A549 144 248 Apoptosis +0.17378116712239233 1.1110397649065911e-30 BR00117001 CACNA2D3 final crispr O07 A549 144 2289 Apoptosis +0.41965205367347225 2.813856946789519e-30 BR00117001 RPL23A final crispr G14 A549 144 379 Apoptosis +0.3774891774891775 8.232507009464348e-30 BR00117005 CDK7 final crispr E12 A549 144 460 Apoptosis +0.14825414345281895 1.9376583938834965e-29 BR00117004 AKR1B1 final crispr L21 A549 144 3024 Apoptosis +0.3716423752619097 2.681314430276581e-29 BR00117005 SLC7A11 final crispr P05 A549 144 465 Apoptosis +0.46491067338524966 2.927703113382408e-29 BR00117001 RPL3 final crispr K04 A549 144 296 Apoptosis +0.3645747542963817 4.764486297444102e-28 BR00117004 S1PR1 final crispr A18 A549 144 467 Apoptosis +0.45475159760874045 5.194740466764623e-28 BR00117004 CA5A final crispr M01 A549 144 294 Apoptosis +0.2740560292326431 1.557859139405901e-27 BR00117004 CDK7 final crispr E12 A549 144 821 Apoptosis +0.34577603143418467 2.2150944725737266e-27 BR00117000 TUBB3 final crispr K11 A549 144 509 Apoptosis +0.1616245621082931 4.92925141844902e-27 BR00117003 GAA final crispr L17 A549 144 2330 Apoptosis +0.40608317815021727 6.1839933673079836e-27 BR00117000 RPL23A final crispr G14 A549 144 358 Apoptosis +0.3046875 1.2709543054801172e-26 BR00117004 TUBB4B final crispr C04 A549 144 640 Apoptosis +0.16729323308270677 2.0900771976625002e-26 BR00117003 HCK final crispr H23 A549 144 2128 Apoptosis +0.16734211148426123 3.476612772014637e-26 BR00117005 AKR1B1 final crispr L21 A549 144 2107 Apoptosis +0.14840445982314496 2.1654804167606853e-25 BR00117004 F10 final crispr H15 A549 144 2601 Apoptosis +0.15069477963466524 2.4535648847682526e-25 BR00117003 AKT1 final crispr J19 A549 144 2505 Apoptosis +0.3796842105263158 9.526569301594134e-25 BR00117004 PPAT final crispr E13 A549 144 375 Apoptosis +0.26308490328158207 2.1883419302834102e-24 BR00117001 AVPR1A final crispr J07 A549 144 781 Apoptosis +0.23961661341853036 4.677946801431488e-24 BR00117000 TUBB4B final crispr C04 A549 144 939 Apoptosis +0.15444656057597153 2.574520201251038e-23 BR00117005 ELANE final crispr N19 A549 144 2192 Apoptosis +0.4335987349497864 4.345211379906882e-23 BR00117001 RPL23A final crispr M18 A549 144 269 Apoptosis +0.31958656629039306 1.0178821813116236e-22 BR00117004 OPRL1 final crispr A11 A549 144 491 Apoptosis +0.25560269444793104 1.1015692379304647e-22 BR00117001 DHH final crispr F05 A549 144 771 Apoptosis +0.1378710032236313 1.3977065560895249e-22 BR00117004 AGER final crispr J18 A549 144 2673 Apoptosis +0.1487544833723175 1.587517555518681e-22 BR00117005 PDPK1 final crispr N18 A549 144 2282 Apoptosis +0.2607841459049812 6.349580703257178e-22 BR00117000 PPAT final crispr E13 A549 144 716 Apoptosis +0.23905119166241023 1.1754982123574177e-21 BR00117001 TUBB4B final crispr C04 A549 144 847 Apoptosis +0.26259927123236476 1.294387329699209e-21 BR00117004 HDAC3 final crispr K19 A549 144 693 Apoptosis +0.15447536376871912 1.5839288228469965e-21 BR00117000 CACNA2D3 final crispr O07 A549 144 2018 Apoptosis +0.4406218814013341 1.719895434658809e-21 BR00117005 ATP5F1D final crispr E15 A549 144 237 Apoptosis +0.30346966911764706 2.4180775422827835e-21 BR00117000 FOXM1 final crispr A19 A549 144 512 Apoptosis +0.312515002914852 2.569068112902629e-21 BR00117003 FFAR2 final crispr A24 A549 144 482 Apoptosis +0.2330327955288411 3.2048866197980596e-21 BR00117000 DHH final crispr F05 A549 144 872 Apoptosis +0.37820475609992066 3.601761954333716e-21 BR00117004 CDK9 final crispr I20 A549 144 322 Apoptosis +0.40386168601716305 3.687252933487612e-21 BR00117005 COMT final crispr A12 A549 144 280 Apoptosis +0.3434343434343434 4.2148939262103074e-21 BR00117005 HRH4 final crispr A08 A549 144 396 Apoptosis +0.4147444595205789 4.217405073658914e-21 BR00117004 RPL23A final crispr G14 A549 144 268 Apoptosis +0.35135135135135137 1.1566159487868266e-20 BR00117003 PPAT final crispr E13 A549 144 370 Apoptosis +0.26163599814442556 1.4804205632387368e-20 BR00117004 FPR1 final crispr N22 A549 144 669 Apoptosis +0.2894101707839313 1.852803573606417e-20 BR00117003 FPR1 final crispr N22 A549 144 541 Apoptosis +0.34657567633438946 2.4424385674850675e-20 BR00117005 CDK7 final crispr I14 A549 144 374 Apoptosis +0.21904761904761905 2.87720410974694e-20 BR00117000 ATP5F1D final crispr G21 A549 144 945 Apoptosis +0.16134054873899953 3.163396579753924e-20 BR00117001 CACNG1 final crispr N23 A549 144 1738 Apoptosis +0.29778538161771695 3.178057699001185e-20 BR00117004 KCNN4 final crispr K01 A549 144 504 Apoptosis +0.4211250983477577 3.4597712977872755e-20 BR00117004 CDK9 final crispr M04 A549 144 246 Apoptosis +0.3420938739040599 3.669381905374345e-20 BR00117004 SLC7A11 final crispr P05 A549 144 376 Apoptosis +0.1533112696018269 3.947750447752636e-20 BR00117001 AGER final crispr J18 A549 144 1918 Apoptosis +0.349862258953168 4.1519549149014966e-20 BR00117004 FOXM1 final crispr A19 A549 144 363 Apoptosis +0.13621476333622756 6.192361358301446e-20 BR00117004 KRAS final crispr D21 A549 144 2404 Apoptosis +0.3769019759118769 7.550368907075197e-20 BR00117002 HDAC3 final crispr K19 A549 144 303 Apoptosis +0.5074074074074074 8.903671636307192e-20 BR00117003 TUBB3 final crispr K11 A549 144 162 Apoptosis +0.33034543912406505 1.5628803934920755e-19 BR00117000 AURKB final crispr C13 A549 144 396 Apoptosis +0.24649859943977592 1.8954472471297656e-19 BR00117004 FFAR2 final crispr A24 A549 144 714 Apoptosis +0.6781609195402298 2.4802390651368844e-19 BR00117003 RPL3 final crispr K04 A549 144 87 Apoptosis +0.3317579327888606 2.5635668666821965e-19 BR00117003 CDK9 final crispr I20 A549 144 388 Apoptosis +0.2893627254509018 5.289332308121105e-19 BR00117004 DHH final crispr F05 A549 144 500 Apoptosis +0.3039497088277576 5.746282521139161e-19 BR00117001 TUBB3 final crispr K11 A549 144 455 Apoptosis +0.3351206434316354 5.990081827362135e-19 BR00117005 KCNN4 final crispr A22 A549 144 373 Apoptosis +0.1335686157167207 6.970456340284595e-19 BR00117003 IL1B final crispr H18 A549 144 2370 Apoptosis +0.2403296449976948 9.290898914837567e-19 BR00117003 SLC29A1 final crispr E03 A549 144 723 Apoptosis +0.23753349699229803 1.3326532390006127e-18 BR00117000 HPGDS final crispr B19 A549 144 731 Apoptosis +0.3119047619047619 1.899469842601048e-18 BR00117004 HRH4 final crispr A08 A549 144 420 Apoptosis +0.14767932489451477 1.913362332398741e-18 BR00117000 AKR1B1 final crispr L21 A549 144 1896 Apoptosis +0.3064516129032258 2.154781869426419e-18 BR00117004 CDK2 final crispr F08 A549 144 434 Apoptosis +0.2071139945373622 2.419571574429672e-18 BR00117004 FLT3 final crispr G16 A549 144 951 Apoptosis +0.3349936263632501 3.082999151349998e-18 BR00117003 CDK4 final crispr P03 A549 144 354 Apoptosis +0.22865023569570872 3.548587725984309e-18 BR00117000 NAMPT final crispr I09 A549 144 768 Apoptosis +0.3015685113939035 4.619958302756619e-18 BR00117001 CDK4 final crispr B15 A549 144 436 Apoptosis +0.24753166869069834 1.0876480850869926e-17 BR00117000 FFAR2 final crispr A24 A549 144 636 Apoptosis +0.3840304182509506 1.122064018806037e-17 BR00117005 NAMPT final crispr I09 A549 144 263 Apoptosis +0.22107703716219387 1.1724640737554428e-17 BR00117003 CDK7 final crispr E12 A549 144 798 Apoptosis +0.25203252032520324 1.4628651619058186e-17 BR00117003 CACNA2D3 final crispr N24 A549 144 615 Apoptosis +0.33851622707044393 1.6630340754905018e-17 BR00117005 TUBB4B final crispr C04 A549 144 332 Apoptosis +0.2274534935469515 1.8308177880998155e-17 BR00117000 CDK7 final crispr I14 A549 144 749 Apoptosis +0.24672351772193293 2.0213268026541078e-17 BR00117000 CYP2A6 final crispr C07 A549 144 631 Apoptosis +0.3504823151125402 2.4029284598826985e-17 BR00117005 HDAC3 final crispr K19 A549 144 311 Apoptosis +0.24243084142349355 2.7228419992892507e-17 BR00117003 BRD4 final crispr M19 A549 144 653 Apoptosis +0.13102584628553765 2.952781950921401e-17 BR00117003 PDE3A final crispr O08 A549 144 2248 Apoptosis +0.3281510953924747 3.027706692974786e-17 BR00117004 KCNN1 final crispr D01 A549 144 351 Apoptosis +0.24566929133858267 3.154003345344137e-17 BR00117004 ABL1 final crispr C01 A549 144 635 Apoptosis +0.3008754442229349 3.222852562748546e-17 BR00117003 TBXAS1 final crispr P08 A549 144 415 Apoptosis +0.22973137740522004 3.3314604740127625e-17 BR00117000 CDK7 final crispr E12 A549 144 724 Apoptosis +0.21820448877805487 3.922551672472785e-17 BR00117000 F10 final crispr H07 A549 144 802 Apoptosis +0.24594978976007914 4.123287197684571e-17 BR00117004 ATP5F1D final crispr G21 A549 144 622 Apoptosis 0.17065422896331647 1.9732465269225203e-41 BR00117004 AKT1 final crispr J19 A549 144 3225 Binuclear 0.19125483657767803 2.1917845559377583e-40 BR00117005 PTK2B final crispr N15 A549 144 2494 Binuclear 0.15065524370160133 2.0706568604545348e-30 BR00117004 AKR1B1 final crispr L21 A549 144 3024 Binuclear @@ -789,6 +7809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.1381621956394582 5.4723696795091e-21 BR00117005 LPAR1 final crispr L01 A549 144 2470 Binuclear 0.163667771638556 7.546403522197239e-21 BR00117001 LPAR1 final crispr L01 A549 144 1739 Binuclear 0.1303344867358708 1.151988329397321e-19 BR00117004 F10 final crispr H15 A549 144 2601 Binuclear +0.15813734725504988 1.7655664296597422e-19 BR00117001 CACNG1 final crispr N23 A549 144 1738 Binuclear +0.11785677137507801 7.607120491071459e-19 BR00117003 TUBB4B final crispr J13 A549 144 3036 Binuclear +0.12626579063718965 1.0341540223913463e-18 BR00117004 MAPK8 final crispr D13 A549 144 2632 Binuclear +0.12145742185662345 1.1195503498088021e-17 BR00117004 AGER final crispr J18 A549 144 2673 Binuclear +0.12601626016260162 1.9659991921367765e-17 BR00117004 TUBB final crispr J17 A549 144 2460 Binuclear +0.12480517159089444 2.6382239019710447e-16 BR00117003 GAA final crispr L17 A549 144 2330 Binuclear +0.13225021292025627 4.07658466409062e-15 BR00117001 AGER final crispr J18 A549 144 1918 Binuclear +0.12096057796404162 1.8661218465027538e-14 BR00117005 ELANE final crispr N19 A549 144 2192 Binuclear +0.17380457380457381 3.4550639707009184e-14 BR00117002 UGT1A9 final crispr J01 A549 144 1040 Binuclear +0.12428525029813484 4.4986910082142976e-14 BR00117000 CACNA2D3 final crispr O07 A549 144 2018 Binuclear +0.2032063414725559 1.2062681676326483e-13 BR00117000 TGFBR1 final crispr B08 A549 144 731 Binuclear +0.1102641858227239 1.3807373959966874e-13 BR00117004 RPL3 final crispr H11 A549 144 2481 Binuclear +0.1221565718311186 2.7503867413757687e-13 BR00117005 CCR1 final crispr O17 A549 144 1976 Binuclear +0.11701127819548872 4.182813768962091e-13 BR00117003 HCK final crispr H23 A549 144 2128 Binuclear +0.11713038739237848 4.671718124593346e-13 BR00117005 AKR1B1 final crispr L21 A549 144 2107 Binuclear +0.11190109574137694 7.057590572335223e-13 BR00117005 PDPK1 final crispr N18 A549 144 2282 Binuclear +0.10366430461879962 7.687725565325208e-13 BR00117003 CACNG1 final crispr N23 A549 144 2650 Binuclear +0.10470503526068374 2.1732919200668615e-12 BR00117003 AKT1 final crispr J19 A549 144 2505 Binuclear +0.11105675812398501 2.5194473124500374e-12 BR00117004 ITGB2 final crispr D23 A549 144 2203 Binuclear +0.16755163053446315 6.221659322143035e-12 BR00117002 AKR1B1 final crispr L21 A549 144 932 Binuclear +0.10365164049322718 1.4700799926249996e-11 BR00117004 EZH2 final crispr H09 A549 144 2374 Binuclear +0.1247262990204386 1.7315773894004344e-11 BR00117001 PTK2B final crispr N15 A549 144 1629 Binuclear +0.10329870035732593 2.9844040534261336e-11 BR00117004 CSK final crispr B05 A549 144 2324 Binuclear +0.11514447660813645 3.4669722947420985e-11 BR00117001 SLC29A1 final crispr N21 A549 144 1860 Binuclear +0.18299104591350734 3.887453429965714e-11 BR00117000 CDK7 final crispr E12 A549 144 724 Binuclear +0.10080876986035056 4.556442771095e-11 BR00117004 KRAS final crispr D21 A549 144 2404 Binuclear +0.17365106706268768 7.950938290995156e-11 BR00117001 AVPR1A final crispr J07 A549 144 781 Binuclear +0.15705948045219337 8.068415856123898e-11 BR00117000 KCNMA1 final crispr E23 A549 144 958 Binuclear +0.22399498362711628 1.1148262836825586e-10 BR00117000 CASP3 final crispr D19 A549 144 465 Binuclear +0.11353794882196042 1.2332718729432271e-10 BR00117004 TUBB3 final crispr F19 A549 144 1809 Binuclear +0.09987141020145734 1.5145708259339388e-10 BR00117004 GAA final crispr L17 A549 144 2333 Binuclear +0.10346856048626125 1.613406615239056e-10 BR00117005 PLA2G1B final crispr J11 A549 144 2152 Binuclear +0.1626056869959309 2.0241016278174335e-10 BR00117000 FGF1 final crispr J12 A549 144 858 Binuclear +0.1489856116341685 2.0799558973526995e-10 BR00117000 ASIC1 final crispr M20 A549 144 1023 Binuclear +0.16548736611695128 2.572882613799629e-10 BR00117000 CDK2 final crispr F08 A549 144 823 Binuclear +0.24340569056473232 2.8512571313510106e-10 BR00117000 RPL3 final crispr K04 A549 144 372 Binuclear +0.2478584729981378 3.51070413652014e-10 BR00117000 RPL23A final crispr G14 A549 144 358 Binuclear +0.09864754566801141 4.1333611550925804e-10 BR00117003 LPAR1 final crispr L01 A549 144 2283 Binuclear +0.1660728548877051 4.448402766279412e-10 BR00117000 ICAM1 final crispr C20 A549 144 799 Binuclear +0.1523809523809524 5.485818445598063e-10 BR00117000 ATP5F1D final crispr G21 A549 144 945 Binuclear +0.14861099444895537 6.36675634509813e-10 BR00117000 RNASE1 final crispr K09 A549 144 983 Binuclear +0.16588557115549404 7.111099609956935e-10 BR00117001 JAK1 final crispr J09 A549 144 778 Binuclear +0.17283033255006924 8.075764368081899e-10 BR00117000 PPAT final crispr E13 A549 144 716 Binuclear +0.15375508694043655 9.64963213298263e-10 BR00117000 DCK final crispr I07 A549 144 900 Binuclear +0.10946495930117134 1.3600818442905263e-09 BR00117004 SCNN1G final crispr P15 A549 144 1752 Binuclear +0.26485341273476865 1.4157334425312346e-09 BR00117001 RPL3 final crispr K04 A549 144 296 Binuclear +0.15963384817222256 1.455865946862439e-09 BR00117000 CSF1R final crispr J15 A549 144 818 Binuclear +0.20235756385068762 1.5680698763394218e-09 BR00117000 TUBB3 final crispr K11 A549 144 509 Binuclear +0.10417525627013785 1.6430591634092868e-09 BR00117000 LPAR1 final crispr L01 A549 144 1916 Binuclear +0.099229344055503 1.6725223311687599e-09 BR00117003 F10 final crispr H15 A549 144 2112 Binuclear +0.10519636400646142 1.7314507014573902e-09 BR00117005 LYN final crispr N13 A549 144 1874 Binuclear +0.10673234811165845 1.7676228715765017e-09 BR00117004 CCR1 final crispr G02 A549 144 1827 Binuclear +0.16602937249666222 1.8078205484937573e-09 BR00117000 CDK7 final crispr I14 A549 144 749 Binuclear +0.09373962175671807 2.368393475035764e-09 BR00117004 PTK2B final crispr N15 A549 144 2324 Binuclear +0.15442719607479333 2.3857749121741548e-09 BR00117003 BRD4 final crispr J16 A549 144 855 Binuclear +0.19781769372304164 2.7959120847674475e-09 BR00117000 CDK4 final crispr B15 A549 144 516 Binuclear +0.14009661835748793 2.844346324950969e-09 BR00117000 JAK1 final crispr J09 A549 144 1035 Binuclear +0.1920085238780922 3.0312819645126544e-09 BR00117005 TGFBR1 final crispr B08 A549 144 543 Binuclear +0.15391719634406606 4.4549803412879315e-09 BR00117001 CDC25A final crispr D06 A549 144 829 Binuclear +0.11906449145016029 4.595545424968037e-09 BR00117001 ITGB2 final crispr D23 A549 144 1396 Binuclear +0.14841015572037622 4.987946100060753e-09 BR00117000 PDE7A final crispr C10 A549 144 893 Binuclear +0.1541055940040497 6.745201143991291e-09 BR00117000 HTR3A final crispr O20 A549 144 812 Binuclear +0.1509433962264151 7.637982429010387e-09 BR00117000 HRH4 final crispr A08 A549 144 848 Binuclear +0.13956583294006608 9.357051212686086e-09 BR00117000 GUCY1B1 final crispr H21 A549 144 978 Binuclear +0.13670619205143736 1.0141540697149557e-08 BR00117003 ITGB2 final crispr D23 A549 144 1016 Binuclear +0.09729561923126431 1.0898997038741e-08 BR00117004 MET final crispr H13 A549 144 1991 Binuclear +0.19502007699631577 1.0989896484972196e-08 BR00117005 KCNN4 final crispr K01 A549 144 493 Binuclear +0.08593113978567717 1.6727991734092128e-08 BR00117004 LPAR1 final crispr L01 A549 144 2498 Binuclear +0.1378959305172547 1.7454096491160144e-08 BR00117000 PPAT final crispr G13 A549 144 964 Binuclear +0.134258277989732 2.0896801393890558e-08 BR00117000 ABL1 final crispr C01 A549 144 1008 Binuclear +0.14456922914689443 2.1168568002176375e-08 BR00117000 DHH final crispr F05 A549 144 872 Binuclear +0.15087281795511223 2.2251604056022394e-08 BR00117000 F10 final crispr H07 A549 144 802 Binuclear +0.10040562345274931 2.4997840588335806e-08 BR00117004 HCK final crispr H23 A549 144 1793 Binuclear +0.11113658312471285 2.7207473127945348e-08 BR00117001 FOXM1 final crispr F23 A549 144 1460 Binuclear +0.1397491881401203 2.9771787304231386e-08 BR00117000 CYP3A4 final crispr D04 A549 144 912 Binuclear +0.13122605363984674 2.981971285870957e-08 BR00117000 MET final crispr H13 A549 144 1044 Binuclear +0.13466893885863918 3.036546436252229e-08 BR00117000 IMPDH1 final crispr G05 A549 144 982 Binuclear +0.1516376788036411 3.3420843661121204e-08 BR00117000 NAMPT final crispr I09 A549 144 768 Binuclear +0.09065807639208467 3.434143278146363e-08 BR00117000 SLC29A1 final crispr N21 A549 144 2173 Binuclear +0.2073170731707317 3.99630258306941e-08 BR00117003 CDK9 final crispr M04 A549 144 410 Binuclear +0.09001096808203105 4.0444584568432444e-08 BR00117005 CSK final crispr B05 A549 144 2170 Binuclear +0.15045412061118335 4.1332775269812646e-08 BR00117000 KCNJ1 final crispr E14 A549 144 768 Binuclear +0.1611851589008893 4.3872629520138345e-08 BR00117004 KRAS final crispr F07 A549 144 673 Binuclear +0.13733905579399142 4.429387863659052e-08 BR00117000 PNLIP final crispr C06 A549 144 932 Binuclear +0.1434386011864936 4.444472636081147e-08 BR00117005 RPL3 final crispr H11 A549 144 846 Binuclear +0.14595735989379022 4.6307291375630064e-08 BR00117000 GRIN2A final crispr P09 A549 144 814 Binuclear +0.13788366788486078 5.0512903396019345e-08 BR00117003 PTGIR final crispr G08 A549 144 913 Binuclear +0.08877570152512894 5.4312008786851746e-08 BR00117004 GUCY1B1 final crispr H21 A549 144 2199 Binuclear +0.21317709141704175 5.453970667597999e-08 BR00117001 RPL23A final crispr G14 A549 144 379 Binuclear +0.08779652688061251 5.5207461213897436e-08 BR00117003 PDE3A final crispr O08 A549 144 2248 Binuclear 0.2972472819801064 7.472204694005271e-16 BR00117000 AURKB final crispr C13 A549 144 396 Elongated 0.33482842911170557 3.445096579826416e-15 BR00117000 PLK1 final crispr G09 A549 144 293 Elongated 0.2596695821185617 9.410488315973805e-11 BR00117001 PLK1 final crispr G09 A549 144 345 Elongated @@ -799,6 +7909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.4189655172413793 1.6063459122774777e-09 BR00117002 AURKB final crispr C13 A549 144 115 Elongated 0.13710703061771476 3.1566669960854537e-09 BR00117001 OPRL1 final crispr A04 A549 144 1068 Elongated 0.300675168792198 4.107145423815524e-09 BR00117000 PLK1 final crispr F13 A549 144 217 Elongated +0.1295776927009205 5.13296278391265e-09 BR00117001 MAPK14 final crispr A20 A549 144 1165 Elongated +0.3133025166923472 4.1151009744255884e-08 BR00117004 AURKB final crispr C13 A549 144 176 Elongated +0.12526529068164477 4.28041379053584e-08 BR00117001 F10 final crispr H07 A549 144 1118 Elongated +0.1297832896751677 6.296167143683657e-08 BR00117001 DDR2 final crispr A03 A549 144 1016 Elongated +0.11962210309309236 6.071640195065777e-07 BR00117001 KCNN4 final crispr K01 A549 144 1033 Elongated +0.15062111801242237 8.642671957548568e-07 BR00117002 PDPK1 final crispr E16 A549 144 644 Elongated +0.14531824955143996 9.250671668956034e-07 BR00117001 SIRT2 final crispr P01 A549 144 679 Elongated +0.1284722222222222 1.24243064414527e-06 BR00117000 CHEK2 final crispr M07 A549 144 864 Elongated +0.49981502034776176 1.9716080586420723e-06 BR00117002 RPL23A final crispr M18 A549 144 51 Elongated +0.11370346273538368 2.5893376394579642e-06 BR00117001 CATSPER4 final crispr A02 A549 144 1039 Elongated +0.1334214002642008 2.7231937212973005e-06 BR00117001 KCNN4 final crispr A22 A549 144 757 Elongated +0.28055077452667815 2.84560071965183e-06 BR00117000 RPL23A final crispr M18 A549 144 166 Elongated +0.1251838535708449 3.1953547104524843e-06 BR00117001 OPRL1 final crispr A11 A549 144 841 Elongated +0.07275687261631851 3.4597491527239566e-06 BR00117005 PTK2B final crispr N15 A549 144 2494 Elongated +0.07214260318479791 4.9678270356372e-06 BR00117005 LPAR1 final crispr L01 A549 144 2470 Elongated +0.13532763532763534 5.064417174535185e-06 BR00117001 COMT final crispr A12 A549 144 702 Elongated +0.08393054109945919 5.936960854425497e-06 BR00117004 AKR1B1 final crispr H17 A549 144 1791 Elongated +0.10672645739910314 5.987740858294302e-06 BR00117001 ITGB2 final crispr A17 A549 144 1115 Elongated +0.13546961850919284 6.506509122302273e-06 BR00117001 AURKB final crispr C13 A549 144 682 Elongated +0.10787992495309569 8.037683570038806e-06 BR00117004 CHRM2 final crispr B07 A549 144 1066 Elongated +0.10088186356073212 8.546312505327108e-06 BR00117000 HIF1A final crispr A01 A549 144 1200 Elongated +0.07766934476179432 9.08416227274719e-06 BR00117000 CACNA2D3 final crispr O07 A549 144 2018 Elongated +0.07275689844497184 9.968101579126832e-06 BR00117001 CACNA2D3 final crispr O07 A549 144 2289 Elongated +0.08403345049579726 1.009391822368933e-05 BR00117004 AKR1C1 final crispr B06 A549 144 1716 Elongated +0.10484158640594092 1.2177228535892373e-05 BR00117001 HSD11B1 final crispr O23 A549 144 1083 Elongated +0.10183298770850359 1.227575240225669e-05 BR00117001 P3H1 final crispr I01 A549 144 1147 Elongated +0.09880139368093935 1.2914482282874961e-05 BR00117001 OPRM1 final crispr C23 A549 144 1215 Elongated +0.08926969806599436 1.626456199155419e-05 BR00117001 HBB final crispr F21 A549 144 1456 Elongated +0.10358952191579493 1.8135797551473636e-05 BR00117001 PTGIR final crispr G08 A549 144 1076 Elongated +0.09051785925088959 2.2532015258365938e-05 BR00117001 UGT1A9 final crispr J01 A549 144 1376 Elongated +0.07520626739927665 2.2756296718717048e-05 BR00117004 MET final crispr H13 A549 144 1991 Elongated +0.09338833546496617 2.317539730734013e-05 BR00117001 ABL1 final crispr P20 A549 144 1291 Elongated +0.1054726368159204 2.7476420294514015e-05 BR00117001 ABL1 final crispr C01 A549 144 1005 Elongated +0.10928374245101588 3.015179420747248e-05 BR00117001 HIF1A final crispr M24 A549 144 918 Elongated +0.091324200913242 3.4420626085324195e-05 BR00117001 GJB4 final crispr N01 A549 144 1314 Elongated +0.0892499360731776 3.519294937250554e-05 BR00117001 EZH2 final crispr H09 A549 144 1362 Elongated +0.1375398783307286 4.461638622714603e-05 BR00117003 FOXM1 final crispr A19 A549 144 557 Elongated +0.07224644977816835 4.686511832385131e-05 BR00117004 GPR119 final crispr P21 A549 144 2025 Elongated +0.10985013822202823 4.882899656989498e-05 BR00117001 ATP5F1D final crispr E15 A549 144 870 Elongated +0.06162700991691486 5.8098718610350796e-05 BR00117003 PORCN final crispr L13 A549 144 2737 Elongated +0.08121184505786322 5.959511673736582e-05 BR00117003 GJB4 final crispr N01 A549 144 1564 Elongated +0.09884858518964479 6.1002570412707936e-05 BR00117004 SLC29A1 final crispr E03 A549 144 1056 Elongated +0.10445155428263268 6.33420256418857e-05 BR00117001 ADA final crispr O24 A549 144 941 Elongated +0.09850072157785024 6.491925387326144e-05 BR00117003 ADA final crispr O24 A549 144 1060 Elongated +0.12264816864341052 6.564316504731878e-05 BR00117002 CHRM3 final crispr B17 A549 144 676 Elongated +0.06825963218054901 6.729403103689244e-05 BR00117005 ELANE final crispr N19 A549 144 2192 Elongated +0.1529184085878944 6.84654557889178e-05 BR00117002 PDE3A final crispr P18 A549 144 434 Elongated +0.18034327236281633 6.889134378702234e-05 BR00117002 ASIC1 final crispr M20 A549 144 307 Elongated +0.2413793103448276 7.369005840189334e-05 BR00117005 TUBB3 final crispr K11 A549 144 174 Elongated +0.14228456913827656 8.002245903716719e-05 BR00117004 TGFBR1 final crispr B08 A549 144 499 Elongated +0.09243209226085938 8.259377230071416e-05 BR00117001 PRKCE final crispr K05 A549 144 1168 Elongated +0.06810860561435803 8.335435272637906e-05 BR00117000 SLC29A1 final crispr N21 A549 144 2173 Elongated +0.08922345544166962 8.605494944118264e-05 BR00117001 BAX final crispr E06 A549 144 1249 Elongated +0.16242228212039533 8.85270997129236e-05 BR00117002 ATP5F1D final crispr E15 A549 144 371 Elongated +0.09098446193398853 9.376949049142972e-05 BR00117001 CLK1 final crispr M11 A549 144 1192 Elongated +0.10643519983127703 9.461967704164362e-05 BR00117000 DHH final crispr F05 A549 144 872 Elongated +0.13512862616310892 0.00012048058820326718 BR00117002 HSD11B1 final crispr O01 A549 144 522 Elongated +0.06666935908990426 0.00012236604502324327 BR00117005 CSK final crispr B05 A549 144 2170 Elongated +0.14319886667131146 0.00012356216846898471 BR00117000 CASP3 final crispr D19 A549 144 465 Elongated +0.06869205654729589 0.0001293310705080988 BR00117003 CDK2 final crispr L19 A549 144 2027 Elongated +0.11592403504241244 0.00013429993292039607 BR00117002 EDNRB final crispr J03 A549 144 710 Elongated +0.13436801561932304 0.0001356692495246572 BR00117005 ICAM1 final crispr I12 A549 144 523 Elongated +0.10125555195977731 0.00013809551769859309 BR00117001 NAMPT final crispr I09 A549 144 924 Elongated +0.1156431334622824 0.0001454795778537318 BR00117001 P2RY12 final crispr P19 A549 144 705 Elongated +0.10938331258998951 0.00015370405334968055 BR00117001 AKR1C1 final crispr B13 A549 144 785 Elongated +0.10429753332311935 0.0001596413332547024 BR00117001 FPR1 final crispr N22 A549 144 854 Elongated +0.3020618556701031 0.00016726338611524572 BR00117003 PLK1 final crispr F13 A549 144 97 Elongated +0.3116959064327485 0.00017305439309333662 BR00117002 TUBB3 final crispr K11 A549 144 95 Elongated +0.05372885998933087 0.0001759014248668505 BR00117004 AKT1 final crispr J19 A549 144 3225 Elongated +0.10967741935483871 0.00017650418071116954 BR00117004 KCTD16 final crispr D03 A549 144 775 Elongated +0.3924242424242424 0.0001773533313432266 BR00117005 PLK1 final crispr G09 A549 144 55 Elongated +0.11906774340001738 0.00018094234790343467 BR00117001 GRIN2A final crispr A23 A549 144 643 Elongated +0.09970250743731407 0.00021731230969808908 BR00117001 PTPN2 final crispr A15 A549 144 905 Elongated +0.08335525012159314 0.00022774160478534745 BR00117001 ANXA1 final crispr G01 A549 144 1291 Elongated +0.07177047399983354 0.00023748141784566781 BR00117001 CACNG1 final crispr N23 A549 144 1738 Elongated +0.06900212314225053 0.000253062297875051 BR00117003 BTK final crispr P17 A549 144 1884 Elongated +0.07140536975405187 0.0002603662430950621 BR00117001 LPAR1 final crispr L01 A549 144 1739 Elongated +0.07645916699172953 0.00027094904302911953 BR00117001 BTK final crispr P17 A549 144 1510 Elongated +0.07998912810363976 0.00027216181235840015 BR00117000 S1PR1 final crispr P23 A549 144 1373 Elongated +0.09810677664432045 0.00027610540411994694 BR00117001 FFAR2 final crispr A06 A549 144 911 Elongated +0.05364052423548991 0.00030240780676272686 BR00117003 TUBB4B final crispr J13 A549 144 3036 Elongated +0.0680379746835443 0.00030713714132266437 BR00117000 AKR1B1 final crispr L21 A549 144 1896 Elongated +0.10258909507013177 0.00031189754046093376 BR00117001 PDE7A final crispr C22 A549 144 823 Elongated +0.0704379695516337 0.0003151450821579366 BR00117004 SCNN1G final crispr P15 A549 144 1752 Elongated +0.11063559993659851 0.00031559868322846604 BR00117005 CACNA2D3 final crispr N24 A549 144 702 Elongated +0.0825529073578111 0.00031745304034464634 BR00117001 ALK final crispr G06 A549 144 1277 Elongated +0.09594706368899918 0.00033656083431392195 BR00117001 KCNMA1 final crispr A07 A549 144 936 Elongated +0.08971962616822429 0.00036069068292135883 BR00117001 RNASE1 final crispr K09 A549 144 1070 Elongated +0.10999727897887498 0.00037052722077899534 BR00117001 PAK4 final crispr M16 A549 144 696 Elongated +0.08958961654459285 0.0003719381760523859 BR00117001 PDE4D final crispr J24 A549 144 1055 Elongated 0.2572108523651688 3.26644953140264e-72 BR00117005 LPAR1 final crispr L01 A549 144 2470 Grape 0.19858167889771575 3.7319766402574917e-56 BR00117004 AKT1 final crispr J19 A549 144 3225 Grape 0.22536802094597488 5.0762023787864535e-56 BR00117005 PTK2B final crispr N15 A549 144 2494 Grape @@ -809,6 +8009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.16869604867114954 2.749101442128809e-39 BR00117004 S100B final crispr D22 A549 144 3123 Grape 0.16580249833561092 9.539228643909625e-37 BR00117004 AKR1B1 final crispr L21 A549 144 3024 Grape 0.1707035755478662 1.6962140570578433e-33 BR00117004 F10 final crispr H15 A549 144 2601 Grape +0.16749879051765845 5.7979965935256595e-33 BR00117003 CACNG1 final crispr N23 A549 144 2650 Grape +0.18134642973373272 5.052912397121356e-32 BR00117005 ELANE final crispr N19 A549 144 2192 Grape +0.16785009390636127 2.4307100619867126e-31 BR00117003 AKT1 final crispr J19 A549 144 2505 Grape +0.1799812030075188 1.6117078300714827e-30 BR00117003 HCK final crispr H23 A549 144 2128 Grape +0.1727947259456494 3.50894063241583e-30 BR00117005 PDPK1 final crispr N18 A549 144 2282 Grape +0.4149514255239413 1.9712908431371688e-29 BR00117000 RPL3 final crispr K04 A549 144 372 Grape +0.19488531494955072 2.103105199628188e-29 BR00117001 CACNG1 final crispr N23 A549 144 1738 Grape +0.1676276174452739 4.9124179434005705e-29 BR00117003 GAA final crispr L17 A549 144 2330 Grape +0.3830275229357798 6.807211530260337e-29 BR00117004 CDK7 final crispr I14 A549 144 436 Grape +0.17157636774755883 1.638725051360995e-27 BR00117005 AKR1B1 final crispr L21 A549 144 2107 Grape +0.187641656361885 2.7029269641627195e-27 BR00117001 LPAR1 final crispr L01 A549 144 1739 Grape +0.43210633125037673 6.456109213794415e-27 BR00117004 GRIN2A final crispr A23 A549 144 314 Grape +0.15741660641827032 1.7763256128042777e-26 BR00117004 KRAS final crispr D21 A549 144 2404 Grape +0.1708026374429834 3.072159659782429e-26 BR00117000 CACNA2D3 final crispr O07 A549 144 2018 Grape +0.32651295758751314 3.5314428022658077e-26 BR00117001 SLC7A11 final crispr P05 A549 144 541 Grape +0.47274582199766807 1.413357299006974e-25 BR00117004 TUBB3 final crispr K11 A549 144 248 Grape +0.24387646432374868 6.511101117562013e-25 BR00117000 TUBB4B final crispr C04 A549 144 939 Grape +0.5619621342512908 9.992234741114198e-25 BR00117000 RPL23A final crispr M18 A549 144 166 Grape +0.15040650406504066 1.1101316987565834e-24 BR00117004 TUBB final crispr J17 A549 144 2460 Grape +0.4276683463124141 1.1213360174880316e-24 BR00117001 RPL3 final crispr K04 A549 144 296 Grape +0.14349933690419386 1.8307762745996375e-24 BR00117004 AGER final crispr J18 A549 144 2673 Grape +0.488914373088685 3.282032498053752e-24 BR00117004 SIRT2 final crispr P01 A549 144 218 Grape +0.3371324629872672 4.434909822841063e-24 BR00117005 SLC7A11 final crispr P05 A549 144 465 Grape +0.16763742820182242 5.5537235743290194e-24 BR00117000 LPAR1 final crispr L01 A549 144 1916 Grape +0.27255494305854017 2.834009717636956e-23 BR00117004 HDAC3 final crispr K19 A549 144 693 Grape +0.24847746650426308 1.1706271479779005e-22 BR00117004 CDK7 final crispr E12 A549 144 821 Grape +0.3564388228067236 6.444383875267346e-22 BR00117004 SLC7A11 final crispr P05 A549 144 376 Grape +0.32321663843402976 8.00992072110639e-22 BR00117005 CDK7 final crispr E12 A549 144 460 Grape +0.14367008458410588 9.42505471206448e-22 BR00117003 IL1B final crispr H18 A549 144 2370 Grape +0.14721207635691486 3.0889990047592946e-21 BR00117003 HSP90AB1 final crispr B04 A549 144 2198 Grape +0.15986953482056704 3.508216368329744e-21 BR00117001 SLC29A1 final crispr N21 A549 144 1860 Grape +0.15809191647017284 6.2849843747980624e-21 BR00117005 LYN final crispr N13 A549 144 1874 Grape +0.14634146341463414 1.0528950613333827e-20 BR00117000 SLC29A1 final crispr N21 A549 144 2173 Grape +0.34538540770109916 1.8792354101867783e-20 BR00117001 RPL23A final crispr G14 A549 144 379 Grape +0.14874939990861258 3.954477684260041e-20 BR00117003 LYN final crispr N13 A549 144 2038 Grape +0.4006131054763358 6.260294250724695e-20 BR00117001 RPL23A final crispr M18 A549 144 269 Grape +0.16536962342812594 6.675497134131272e-20 BR00117001 PTK2B final crispr N15 A549 144 1629 Grape +0.2570889443170791 7.306905492003767e-20 BR00117004 FPR1 final crispr N22 A549 144 669 Grape +0.21481481481481482 1.6765560313264821e-19 BR00117000 ATP5F1D final crispr G21 A549 144 945 Grape +0.1373733693292303 2.194206049629276e-19 BR00117003 CHRM3 final crispr B17 A549 144 2300 Grape +0.14977969742253855 2.9626148526630027e-19 BR00117001 AGER final crispr J18 A549 144 1918 Grape +0.23067331670822944 4.088923333680967e-19 BR00117000 F10 final crispr H07 A549 144 802 Grape +0.15031645569620253 4.266073605780906e-19 BR00117000 AKR1B1 final crispr L21 A549 144 1896 Grape +0.291062124248497 4.38636232541208e-19 BR00117004 DHH final crispr F05 A549 144 500 Grape +0.30028001976610114 4.959465600135906e-19 BR00117004 S1PR1 final crispr A18 A549 144 467 Grape +0.13094443262147132 5.175778766812518e-19 BR00117004 RPL3 final crispr H11 A549 144 2481 Grape +0.2937227804259113 7.926569090109993e-19 BR00117003 FFAR2 final crispr A24 A549 144 482 Grape +0.12562582466866068 1.3394936660902478e-18 BR00117004 MAPK8 final crispr D13 A549 144 2632 Grape +0.3398172708517536 1.735371592658624e-18 BR00117004 KCNN1 final crispr D01 A549 144 351 Grape +0.3248421052631579 3.629033279759556e-18 BR00117004 PPAT final crispr E13 A549 144 375 Grape +0.28094302554027506 4.305900586956958e-18 BR00117000 TUBB3 final crispr K11 A549 144 509 Grape +0.25 5.722950416027579e-18 BR00117004 TUBB4B final crispr C04 A549 144 640 Grape +0.14153421687686352 6.399009273358458e-18 BR00117000 LYN final crispr N13 A549 144 1995 Grape +0.31565656565656564 7.784971618662205e-18 BR00117005 HRH4 final crispr A08 A549 144 396 Grape +0.13116382950813635 1.3547837738938325e-17 BR00117003 LPAR1 final crispr L01 A549 144 2283 Grape +0.27729065678167475 1.7563351787669828e-17 BR00117004 KCNN4 final crispr K01 A549 144 504 Grape +0.22919244138093556 1.969354921166841e-17 BR00117004 GHSR final crispr B20 A549 144 738 Grape +0.23249299719887956 2.4982717330557853e-17 BR00117004 FFAR2 final crispr A24 A549 144 714 Grape +0.22974873213462424 3.0808098112590835e-17 BR00117003 SLC29A1 final crispr E03 A549 144 723 Grape +0.12664739798664687 3.156148871885734e-17 BR00117004 PLA2G1B final crispr J11 A549 144 2393 Grape +0.20902404302435937 3.5492122455484485e-17 BR00117000 DHH final crispr F05 A549 144 872 Grape +0.2461095308764119 4.0791523335376196e-17 BR00117004 ATP5F1D final crispr G21 A549 144 622 Grape +0.2754850466287919 5.184162079446305e-17 BR00117004 OPRL1 final crispr A11 A549 144 491 Grape +0.19617451939373395 9.365668879787419e-17 BR00117000 ATP5F1D final crispr E15 A549 144 963 Grape +0.3892886531155348 1.0510612869226792e-16 BR00117005 ATP5F1D final crispr E15 A549 144 237 Grape +0.25984211762543274 1.5461088860445506e-16 BR00117003 FPR1 final crispr N22 A549 144 541 Grape +0.21393418909315035 1.672797130946068e-16 BR00117000 ICAM1 final crispr C20 A549 144 799 Grape +0.34869099154813443 1.7777054207922608e-16 BR00117004 CA5A final crispr M01 A549 144 294 Grape +0.2777226830147854 1.8933943098526315e-16 BR00117004 SSTR2 final crispr P10 A549 144 470 Grape +0.21733505821474774 2.124186460082628e-16 BR00117000 IGF1R final crispr E19 A549 144 773 Grape +0.2909378468368479 2.360180085249297e-16 BR00117003 DCK final crispr I07 A549 144 424 Grape +0.24227642276422764 3.0156949515650476e-16 BR00117003 CACNA2D3 final crispr N24 A549 144 615 Grape +0.2347832399042762 3.0840334416278856e-16 BR00117003 BRD4 final crispr M19 A549 144 653 Grape +0.31440099317194287 3.8470047556985017e-16 BR00117000 RPL23A final crispr G14 A549 144 358 Grape +0.2540813926135027 4.571754490572059e-16 BR00117004 HTR3A final crispr O20 A549 144 545 Grape +0.23639455782312926 4.618595098842596e-16 BR00117000 FFAR2 final crispr A24 A549 144 636 Grape +0.12612606900268689 5.091487466397695e-16 BR00117003 PDE3A final crispr O08 A549 144 2248 Grape +0.1927266234152729 5.67405666841259e-16 BR00117004 FLT3 final crispr G16 A549 144 951 Grape +0.35866123925825416 9.079304019989087e-16 BR00117004 RPL23A final crispr G14 A549 144 268 Grape +0.21873880739188417 1.1842980676073219e-15 BR00117000 CDK7 final crispr E12 A549 144 724 Grape +0.19810810253661654 1.2919120325869849e-15 BR00117004 PRKCE final crispr I17 A549 144 878 Grape +0.13588110403397027 1.4159972243722951e-15 BR00117003 BTK final crispr P17 A549 144 1884 Grape +0.2963582808943634 1.6752080272900922e-15 BR00117003 CDK9 final crispr I20 A549 144 388 Grape +0.20135591895746635 1.842246639555561e-15 BR00117001 TUBB4B final crispr C04 A549 144 847 Grape +0.21564942001011936 2.101042771267493e-15 BR00117000 HPGDS final crispr B19 A549 144 731 Grape +0.12578333065454125 2.4417339818704476e-15 BR00117005 PLA2G1B final crispr J11 A549 144 2152 Grape +0.2833333333333333 2.9766716959917165e-15 BR00117004 HRH4 final crispr A08 A549 144 420 Grape +0.4469135802469136 3.007290268369631e-15 BR00117003 TUBB3 final crispr K11 A549 144 162 Grape +0.18731768375968944 3.0356408637156623e-15 BR00117004 KCNJ1 final crispr E14 A549 144 964 Grape +0.30528933163369687 3.2950138766890817e-15 BR00117003 CDK4 final crispr P03 A549 144 354 Grape 0.20698974500972414 9.623380665645377e-47 BR00117005 LPAR1 final crispr L01 A549 144 2470 Hole 0.16696611409735834 8.690153420914329e-31 BR00117005 PTK2B final crispr N15 A549 144 2494 Hole 0.16825589805761454 8.356592771273761e-29 BR00117001 CACNA2D3 final crispr O07 A549 144 2289 Hole @@ -819,6 +8109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.1625384820049793 1.457606178157791e-20 BR00117001 LPAR1 final crispr L01 A549 144 1739 Hole 0.2556783090537663 4.6256663280136355e-20 BR00117001 AURKB final crispr C13 A549 144 682 Hole 0.12147909298939047 5.36731187381319e-20 BR00117003 TUBB4B final crispr J13 A549 144 3036 Hole +0.14154872046917238 1.219506903493304e-19 BR00117005 ELANE final crispr N19 A549 144 2192 Hole +0.1148099021035482 6.031805330292566e-19 BR00117004 AKT1 final crispr J19 A549 144 3225 Hole +0.15066070386484315 7.406491517746632e-19 BR00117001 SLC29A1 final crispr N21 A549 144 1860 Hole +0.13418081210701513 2.3790014748758327e-18 BR00117005 PDPK1 final crispr N18 A549 144 2282 Hole +0.13815789473684212 4.0579482536024155e-18 BR00117003 HCK final crispr H23 A549 144 2128 Hole +0.1273501481998905 1.0111205338723719e-16 BR00117003 CHRM3 final crispr B17 A549 144 2300 Hole +0.4119120700550691 1.292628354439941e-16 BR00117003 AURKB final crispr C13 A549 144 212 Hole +0.14696848154801584 8.235936244083755e-16 BR00117001 PTK2B final crispr N15 A549 144 1629 Hole +0.1358536664413171 1.4060253638960682e-15 BR00117005 LYN final crispr N13 A549 144 1874 Hole +0.14957843119246067 2.247642285162586e-15 BR00117003 LPAR1 final crispr B16 A549 144 1529 Hole +0.12872900162145176 3.3138952799327884e-15 BR00117003 LYN final crispr N13 A549 144 2038 Hole +0.12723367727143856 9.825441054513868e-15 BR00117000 CACNA2D3 final crispr O07 A549 144 2018 Hole +0.11265736683058464 2.7609450200123532e-14 BR00117003 AKT1 final crispr J19 A549 144 2505 Hole +0.1019854972532539 6.310220434210643e-14 BR00117004 PORCN final crispr L13 A549 144 2968 Hole +0.12738853503184713 9.786833907114653e-14 BR00117003 BTK final crispr P17 A549 144 1884 Hole +0.10848141643800781 1.9923626805255165e-12 BR00117003 GAA final crispr L17 A549 144 2330 Hole +0.3958691910499139 2.6771036993073805e-12 BR00117000 RPL23A final crispr M18 A549 144 166 Hole +0.11877267382630567 3.0699450217883584e-12 BR00117000 LPAR1 final crispr L01 A549 144 1916 Hole +0.29921132736832395 3.885236833779061e-12 BR00117000 PLK1 final crispr G09 A549 144 293 Hole +0.10998619420156466 7.317699322168248e-12 BR00117000 SLC29A1 final crispr N21 A549 144 2173 Hole +0.10284552845528455 9.616696507502413e-12 BR00117004 TUBB final crispr J17 A549 144 2460 Hole +0.11239138202459802 1.2592954952984262e-11 BR00117003 CDK2 final crispr L19 A549 144 2027 Hole +0.3716936312275295 1.617742771528713e-11 BR00117004 AURKB final crispr C13 A549 144 176 Hole +0.11650098686773878 1.991602823178805e-11 BR00117004 AVPR1A final crispr J07 A549 144 1852 Hole +0.38417508417508417 2.340789652045461e-11 BR00117003 TUBB3 final crispr K11 A549 144 162 Hole +0.21101610632499387 2.6994138643575665e-11 BR00117003 FOXM1 final crispr A19 A549 144 557 Hole +0.11941167179658704 2.9551613364714406e-11 BR00117003 CDK4 final crispr B15 A549 144 1738 Hole +0.11448665459626688 7.72002026909963e-11 BR00117000 SCNN1G final crispr P15 A549 144 1821 Hole +0.25650061266742724 1.6410139051425947e-10 BR00117001 PLK1 final crispr G09 A549 144 345 Hole +0.10704785043391217 2.0424621416842436e-10 BR00117000 LYN final crispr N13 A549 144 1995 Hole +0.11989938455933671 2.9356584396199555e-10 BR00117001 HCK final crispr H23 A549 144 1561 Hole +0.10043806116621101 3.8963699651604537e-10 BR00117003 HSP90AB1 final crispr B04 A549 144 2198 Hole +0.4783625730994152 4.046907404719785e-10 BR00117002 TUBB3 final crispr K11 A549 144 95 Hole +0.11958713013741477 4.2038132069975617e-10 BR00117001 LYN final crispr N13 A549 144 1550 Hole +0.08444759802375697 7.805420424573838e-10 BR00117004 AKR1B1 final crispr L21 A549 144 3024 Hole +0.5878787878787879 8.865584812840327e-10 BR00117005 PLK1 final crispr G09 A549 144 55 Hole +0.09939673573795109 1.0952077360203535e-09 BR00117003 KCNQ2 final crispr P13 A549 144 2141 Hole +0.11367781155015197 1.1265294886657916e-09 BR00117001 RGS4 final crispr N11 A549 144 1645 Hole +0.150035765379113 1.1824229356983738e-09 BR00117002 AKR1B1 final crispr L21 A549 144 932 Hole +0.10548523206751055 1.330640277066403e-09 BR00117000 AKR1B1 final crispr L21 A549 144 1896 Hole +0.08996539792387544 1.4050630436252907e-09 BR00117004 F10 final crispr H15 A549 144 2601 Hole +0.2604060362609923 1.4706709146836616e-09 BR00117004 CDK4 final crispr P03 A549 144 302 Hole +0.41851574212893555 1.6498211886262293e-09 BR00117002 AURKB final crispr C13 A549 144 115 Hole +0.08808417997097243 2.093704400135841e-09 BR00117003 CACNG1 final crispr N23 A549 144 2650 Hole +0.189689828890729 2.1492473245360776e-09 BR00117005 GUCY1B1 final crispr H21 A549 144 562 Hole +0.11702968589761042 2.372677920271662e-09 BR00117001 TNF final crispr N17 A549 144 1485 Hole +0.1086320509200513 2.9897251173177762e-09 BR00117005 CDK2 final crispr L19 A549 144 1714 Hole +0.1024234640565095 3.115123690473329e-09 BR00117001 AGER final crispr J18 A549 144 1918 Hole +0.09518806848720833 5.829167631885152e-09 BR00117005 PLA2G1B final crispr J11 A549 144 2152 Hole +0.2314245810055866 5.882114719941303e-09 BR00117000 RPL23A final crispr G14 A549 144 358 Hole +0.29510703363914376 7.251662608845224e-09 BR00117004 SIRT2 final crispr P01 A549 144 218 Hole +0.10560490622445856 7.28620349548777e-09 BR00117001 ELANE final crispr N19 A549 144 1729 Hole +0.09004947370174507 7.633401630595082e-09 BR00117004 EZH2 final crispr H09 A549 144 2374 Hole +0.1648915268112976 8.243795217492094e-09 BR00117001 PPAT final crispr E13 A549 144 698 Hole +0.29347336834208554 9.19487056760017e-09 BR00117000 PLK1 final crispr F13 A549 144 217 Hole +0.09512493210211842 9.639670564451691e-09 BR00117005 AKR1B1 final crispr L21 A549 144 2107 Hole +0.08373810739911872 1.26665556469695e-08 BR00117004 AGER final crispr J18 A549 144 2673 Hole +0.11948249619482496 1.373515187438274e-08 BR00117001 GJB4 final crispr N01 A549 144 1314 Hole +0.18818055681235485 1.9210777857230328e-08 BR00117000 CDK4 final crispr B15 A549 144 516 Hole +0.09279810283535449 2.1933804364919294e-08 BR00117003 F10 final crispr H15 A549 144 2112 Hole +0.31781248016250874 2.239955225852798e-08 BR00117003 SIRT2 final crispr P01 A549 144 178 Hole +0.10089966899383881 2.2552172458862915e-08 BR00117001 MAPK8 final crispr D13 A549 144 1788 Hole +0.5730669626341103 2.3686525979999047e-08 BR00117002 RPL23A final crispr M18 A549 144 51 Hole +0.17517006802721088 2.7005675184703223e-08 BR00117002 PPARD final crispr N03 A549 144 588 Hole +0.13571844095404303 3.7303229697057575e-08 BR00117003 PPAT final crispr G13 A549 144 954 Hole +0.08582023723454672 3.880485325734545e-08 BR00117004 KRAS final crispr D21 A549 144 2404 Hole +0.1026216983667037 4.806572851980377e-08 BR00117001 HPGDS final crispr P14 A549 144 1659 Hole +0.13256490826074505 6.291537347822733e-08 BR00117005 ADA final crispr O06 A549 144 973 Hole +0.09401718524551758 7.762194964906904e-08 BR00117000 CACNG1 final crispr N23 A549 144 1912 Hole +0.1366201060920321 7.86028395549106e-08 BR00117002 COMT final crispr M02 A549 144 905 Hole +0.09553635069264725 8.007875878349164e-08 BR00117005 KCNQ2 final crispr P13 A549 144 1857 Hole +0.08833599741527369 8.159699662091039e-08 BR00117005 CSK final crispr B05 A549 144 2170 Hole +0.08593633135495511 8.912561709261121e-08 BR00117003 LPAR1 final crispr L01 A549 144 2283 Hole +0.09669636228656273 9.285912909937835e-08 BR00117004 AKR1B1 final crispr H17 A549 144 1791 Hole +0.11788967188555238 1.0043502129146327e-07 BR00117001 GAA final crispr L17 A549 144 1194 Hole +0.08158143655779088 1.213333916263241e-07 BR00117004 RPL3 final crispr H11 A549 144 2481 Hole +0.21081081081081082 1.3056449827502033e-07 BR00117003 PPAT final crispr E13 A549 144 370 Hole +0.10287904310839444 1.3833912997620002e-07 BR00117001 TUBB4B final crispr J13 A549 144 1549 Hole +0.09987745098039216 1.66371756413264e-07 BR00117000 P2RY12 final crispr P19 A549 144 1632 Hole +0.07154915145693244 2.0934296996788434e-07 BR00117004 S100B final crispr D22 A549 144 3123 Hole +0.09088266784022911 2.372234159253091e-07 BR00117000 NTRK1 final crispr P07 A549 144 1912 Hole +0.08201021903317118 2.895469770653694e-07 BR00117004 PTK2B final crispr N15 A549 144 2324 Hole +0.1219845260542935 3.568856537193662e-07 BR00117003 TGM2 final crispr B09 A549 144 1032 Hole +0.1049388366309649 3.8338697029271215e-07 BR00117000 KCNQ2 final crispr P13 A549 144 1393 Hole +0.1051349562372464 4.2398906802365343e-07 BR00117001 UGT1A9 final crispr J01 A549 144 1376 Hole +0.41379310344827586 4.716088985641062e-07 BR00117003 RPL3 final crispr K04 A549 144 87 Hole +0.1450140831919827 4.769589993491706e-07 BR00117000 PPAT final crispr E13 A549 144 716 Hole +0.11862835959221502 4.943534849413242e-07 BR00117000 FPR1 final crispr I18 A549 144 1079 Hole +0.12673056443024494 5.461745569325454e-07 BR00117000 TUBB4B final crispr C04 A549 144 939 Hole +0.08412038133585978 5.60097624818691e-07 BR00117004 IGF1R final crispr M22 A549 144 2111 Hole 0.22968540330997464 1.535202909892432e-57 BR00117005 LPAR1 final crispr L01 A549 144 2470 Interphase 0.21934006529359745 4.543365511831873e-53 BR00117005 PTK2B final crispr N15 A549 144 2494 Interphase 0.19112866871398568 5.898060789043158e-52 BR00117004 AKT1 final crispr J19 A549 144 3225 Interphase @@ -829,6 +8209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.18030077110578296 1.2232327847163536e-31 BR00117005 ELANE final crispr N19 A549 144 2192 Interphase 0.15838783118472352 1.8843786124625585e-29 BR00117003 CACNG1 final crispr N23 A549 144 2650 Interphase 0.1446659237912264 5.988252715775829e-29 BR00117004 S100B final crispr D22 A549 144 3123 Interphase +0.18428416473003664 2.7495400468354525e-26 BR00117001 CACNG1 final crispr N23 A549 144 1738 Interphase +0.16881335211652393 1.2249260619268133e-25 BR00117000 CACNA2D3 final crispr O07 A549 144 2018 Interphase +0.1318603489961106 2.290084746856466e-23 BR00117004 AKR1B1 final crispr L21 A549 144 3024 Interphase +0.15695488721804512 2.7864096926283807e-23 BR00117003 HCK final crispr H23 A549 144 2128 Interphase +0.14421818772670142 3.752890715852096e-23 BR00117003 AKT1 final crispr J19 A549 144 2505 Interphase +0.15042153201098082 5.887866405098324e-23 BR00117005 PDPK1 final crispr N18 A549 144 2282 Interphase +0.14752818078454716 1.2551127431599749e-22 BR00117003 GAA final crispr L17 A549 144 2330 Interphase +0.15468265297099476 1.7570259687064217e-22 BR00117005 AKR1B1 final crispr L21 A549 144 2107 Interphase +0.1410569105691057 9.484860827350497e-22 BR00117004 TUBB final crispr J17 A549 144 2460 Interphase +0.13341022683583237 1.3801161348303316e-20 BR00117004 F10 final crispr H15 A549 144 2601 Interphase +0.16133293808746332 2.8262809678538484e-20 BR00117001 LPAR1 final crispr L01 A549 144 1739 Interphase +0.15359029063945917 3.2251690551216945e-20 BR00117000 LPAR1 final crispr L01 A549 144 1916 Interphase +0.15348101265822786 6.798948775039197e-20 BR00117000 AKR1B1 final crispr L21 A549 144 1896 Interphase +0.15099283638540803 4.17920492120463e-19 BR00117005 LYN final crispr N13 A549 144 1874 Interphase +0.32190222839077803 1.2767536790598389e-18 BR00117000 AURKB final crispr C13 A549 144 396 Interphase +0.13077743585870982 1.2664135562939926e-17 BR00117003 CHRM3 final crispr B17 A549 144 2300 Interphase +0.14427467022585846 2.5658970144591398e-17 BR00117001 SLC29A1 final crispr N21 A549 144 1860 Interphase +0.1261876429097727 4.1309101634272193e-17 BR00117004 KRAS final crispr D21 A549 144 2404 Interphase +0.1308608852422217 6.657789539247652e-17 BR00117003 HSP90AB1 final crispr B04 A549 144 2198 Interphase +0.13069489185457892 1.3762685606967293e-16 BR00117000 SLC29A1 final crispr N21 A549 144 2173 Interphase +0.13763089371140227 2.648286258426735e-16 BR00117001 AGER final crispr J18 A549 144 1918 Interphase +0.1959531416400426 3.540761464672736e-16 BR00117000 TUBB4B final crispr C04 A549 144 939 Interphase +0.12906355477438522 4.0210482069165617e-16 BR00117005 PLA2G1B final crispr J11 A549 144 2152 Interphase +0.14815819106908149 4.942422299501797e-16 BR00117001 PTK2B final crispr N15 A549 144 1629 Interphase +0.12256818095629309 5.349040036611205e-16 BR00117004 EZH2 final crispr H09 A549 144 2374 Interphase +0.13245180185788102 9.709973287305655e-16 BR00117000 LYN final crispr N13 A549 144 1995 Interphase +0.12684799428639448 1.0625994969149264e-15 BR00117005 CSK final crispr B05 A549 144 2170 Interphase +0.1378739994080646 1.2279151347576016e-14 BR00117005 CDK2 final crispr L19 A549 144 1714 Interphase +0.10986514625070846 1.527599065217105e-14 BR00117004 AGER final crispr J18 A549 144 2673 Interphase +0.131104033970276 1.5870843339967678e-14 BR00117003 BTK final crispr P17 A549 144 1884 Interphase +0.29132433912767736 1.7907070782493148e-14 BR00117000 RPL3 final crispr K04 A549 144 372 Interphase +0.1928842328304715 3.398673360240527e-14 BR00117001 OPRL1 final crispr A11 A549 144 841 Interphase +0.10954557942966117 3.4911799007676125e-14 BR00117004 MAPK8 final crispr D13 A549 144 2632 Interphase +0.21980622663562688 4.550907581156706e-14 BR00117001 GRIN2A final crispr A23 A549 144 643 Interphase +0.1223395948491433 8.941530642121819e-14 BR00117003 LYN final crispr N13 A549 144 2038 Interphase +0.12242627045957856 1.0134509801864772e-13 BR00117003 CDK2 final crispr L19 A549 144 2027 Interphase +0.19815059445178335 2.0679531491205597e-13 BR00117001 KCNN4 final crispr A22 A549 144 757 Interphase +0.1325227963525836 5.261831202560091e-13 BR00117001 RGS4 final crispr N11 A549 144 1645 Interphase +0.30645900137425564 7.568300189263037e-13 BR00117001 RPL3 final crispr K04 A549 144 296 Interphase +0.11137180086115835 9.109763538033942e-13 BR00117003 LPAR1 final crispr L01 A549 144 2283 Interphase +0.1276499332541364 1.1778224504306333e-12 BR00117004 AKR1C1 final crispr B06 A549 144 1716 Interphase +0.1180785511110565 1.962499102146857e-12 BR00117005 CCR1 final crispr O17 A549 144 1976 Interphase +0.17110468453883607 3.8882778011388524e-12 BR00117001 FFAR2 final crispr A06 A549 144 911 Interphase +0.15515695067264573 3.9966133983573395e-12 BR00117001 ITGB2 final crispr A17 A549 144 1115 Interphase +0.2362151949979758 5.069659140755176e-12 BR00117002 HPGDS final crispr P14 A549 144 470 Interphase +0.12123690712906278 5.990926018172595e-12 BR00117004 AKR1B1 final crispr H17 A549 144 1791 Interphase +0.1775555001391853 6.45221200246795e-12 BR00117001 CDC25A final crispr D06 A549 144 829 Interphase +0.20650406504065041 6.891433261191649e-12 BR00117003 CACNA2D3 final crispr N24 A549 144 615 Interphase +0.10993071593533488 8.279504506311785e-12 BR00117000 ELANE final crispr N19 A549 144 2165 Interphase +0.1164136720024347 9.297346010847495e-12 BR00117000 CACNG1 final crispr N23 A549 144 1912 Interphase +0.24311926605504589 1.0215382231496039e-11 BR00117004 CDK7 final crispr I14 A549 144 436 Interphase +0.20672365724001196 1.155906004017022e-11 BR00117004 IGF1R final crispr E19 A549 144 599 Interphase +0.11435090611719423 2.2200930588100596e-11 BR00117000 NTRK1 final crispr P07 A549 144 1912 Interphase +0.24235294117647058 2.3144732197487008e-11 BR00117002 SLC7A11 final crispr P05 A549 144 425 Interphase +0.16329579243930653 3.595722609499991e-11 BR00117001 HIF1A final crispr M24 A549 144 918 Interphase +0.1439618369182316 3.6129131629886525e-11 BR00117001 GHSR final crispr A09 A549 144 1185 Interphase +0.10680614788268213 3.990267762377215e-11 BR00117003 KCNQ2 final crispr P13 A549 144 2141 Interphase +0.09900990581175695 4.9490771172223295e-11 BR00117004 RPL3 final crispr H11 A549 144 2481 Interphase +0.17174177831912302 5.4766190214267495e-11 BR00117004 CDK7 final crispr E12 A549 144 821 Interphase +0.39594594594594595 5.853147436379709e-11 BR00117005 AURKB final crispr C13 A549 144 150 Interphase +0.17026938508147058 6.375080536403286e-11 BR00117004 BTK final crispr D24 A549 144 828 Interphase +0.2216744967593704 6.3943335822504e-11 BR00117002 GPR119 final crispr P21 A549 144 484 Interphase +0.10162301856452761 6.647075225480075e-11 BR00117004 PTK2B final crispr N15 A549 144 2324 Interphase +0.10327219840055799 6.837526710802138e-11 BR00117003 PDE3A final crispr O08 A549 144 2248 Interphase +0.1185794411937818 6.929491638355995e-11 BR00117000 RGS4 final crispr N11 A549 144 1700 Interphase +0.11406844106463879 7.549928777484322e-11 BR00117000 TNF final crispr N17 A549 144 1841 Interphase +0.1592221457750045 7.949314456003781e-11 BR00117005 TGFBR1 final crispr P24 A549 144 938 Interphase +0.18256769825918762 8.31673583295522e-11 BR00117001 P2RY12 final crispr P19 A549 144 705 Interphase +0.20068027210884354 9.027638705210208e-11 BR00117002 PPARD final crispr N03 A549 144 588 Interphase +0.12346935796651166 9.681082468091354e-11 BR00117001 LYN final crispr N13 A549 144 1550 Interphase +0.15784453981878874 1.2219325982314777e-10 BR00117002 AKR1B1 final crispr L21 A549 144 932 Interphase +0.1636963965987923 1.6261006847658304e-10 BR00117000 ITGB2 final crispr A17 A549 144 855 Interphase +0.16071428571428573 1.6299511637683994e-10 BR00117001 SLCO2B1 final crispr I24 A549 144 896 Interphase +0.11221328334504933 1.663301445317431e-10 BR00117000 PTK2B final crispr N15 A549 144 1829 Interphase +0.11847220837665019 1.835595165156084e-10 BR00117000 MAPK8 final crispr D07 A549 144 1633 Interphase +0.160183769163686 1.9833097582305528e-10 BR00117001 KCNN1 final crispr D01 A549 144 890 Interphase +0.18449814294773076 1.98834774796785e-10 BR00117001 TGM2 final crispr B09 A549 144 665 Interphase +0.10682013785653531 2.204002712270941e-10 BR00117004 MET final crispr H13 A549 144 1991 Interphase +0.16326447528199514 2.844799569887845e-10 BR00117004 MMP2 final crispr D14 A549 144 845 Interphase +0.11101052444618432 3.1382226177475756e-10 BR00117000 SCNN1G final crispr P15 A549 144 1821 Interphase +0.21725495613732126 3.5306616834086036e-10 BR00117005 SLC7A11 final crispr P05 A549 144 465 Interphase +0.1436604132445751 3.718827658543169e-10 BR00117001 PTGIR final crispr G08 A549 144 1076 Interphase +0.102584949542731 4.0167489561007647e-10 BR00117003 F10 final crispr H15 A549 144 2112 Interphase +0.18005040543502082 4.121512460542896e-10 BR00117001 KCNN1 final crispr B24 A549 144 676 Interphase +0.17616266546366405 4.866919080320458e-10 BR00117005 CACNA2D3 final crispr N24 A549 144 702 Interphase +0.11017490757750498 4.930537280046986e-10 BR00117000 GAA final crispr L17 A549 144 1813 Interphase +0.16763817413497342 5.770778219756262e-10 BR00117001 DHH final crispr F05 A549 144 771 Interphase +0.2388638832841844 6.205830390690123e-10 BR00117001 RPL23A final crispr G14 A549 144 379 Interphase +0.17786204483909837 6.858754152745386e-10 BR00117001 AURKB final crispr C13 A549 144 682 Interphase +0.18958018101518137 7.227941550687789e-10 BR00117001 FFAR2 final crispr A24 A549 144 598 Interphase 0.2069648006278899 3.089756308116566e-47 BR00117005 PTK2B final crispr N15 A549 144 2494 Large 0.1690946140130817 1.1143576202584991e-40 BR00117004 AKT1 final crispr J19 A549 144 3225 Large 0.4540540540540541 9.518071523430009e-35 BR00117003 PPAT final crispr E13 A549 144 370 Large @@ -839,6 +8309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.4034428251985504 3.2921251382493755e-29 BR00117000 AURKB final crispr C13 A549 144 396 Large 0.3513482942720116 1.1032265156234764e-28 BR00117000 CDK4 final crispr B15 A549 144 516 Large 0.40073684210526317 1.3742559969570445e-27 BR00117004 PPAT final crispr E13 A549 144 375 Large +0.521215130450483 8.033643335701582e-27 BR00117003 AURKB final crispr C13 A549 144 212 Large +0.4598984630749598 4.2571735675223306e-26 BR00117001 RPL23A final crispr M18 A549 144 269 Large +0.2720494087519771 4.619323509834396e-26 BR00117001 AVPR1A final crispr J07 A549 144 781 Large +0.36009174311926606 1.6533890875326987e-25 BR00117004 CDK7 final crispr I14 A549 144 436 Large +0.4989381583418281 2.9589792896597945e-25 BR00117004 SIRT2 final crispr P01 A549 144 218 Large +0.13548258523424087 1.1865606950177018e-24 BR00117004 AKR1B1 final crispr L21 A549 144 3024 Large +0.5574440619621343 1.3463948361352547e-24 BR00117000 RPL23A final crispr M18 A549 144 166 Large +0.5852252252252252 1.9615185471851996e-24 BR00117005 AURKB final crispr C13 A549 144 150 Large +0.42328042328042326 2.8038624408399534e-24 BR00117004 CA5A final crispr M01 A549 144 294 Large +0.3104481848564004 1.145733388282978e-23 BR00117001 SLC7A11 final crispr P05 A549 144 541 Large +0.37075473029221284 1.3928585603602573e-23 BR00117001 RPL23A final crispr G14 A549 144 379 Large +0.34059104553333613 5.342950526945158e-23 BR00117001 CDK4 final crispr B15 A549 144 436 Large +0.368032278088144 2.8863291352677316e-22 BR00117000 RPL23A final crispr G14 A549 144 358 Large +0.33819306000982347 1.4331829241740981e-21 BR00117003 CDK2 final crispr F08 A549 144 415 Large +0.3899576593203778 4.573863182157734e-21 BR00117004 CDK4 final crispr P03 A549 144 302 Large +0.412483039348711 9.243219419023189e-21 BR00117004 RPL23A final crispr G14 A549 144 268 Large +0.49349330286294674 2.1475971975290912e-20 BR00117003 SIRT2 final crispr P01 A549 144 178 Large +0.4956343091936312 3.657800316384179e-20 BR00117004 AURKB final crispr C13 A549 144 176 Large +0.32027649769585254 4.420836558182812e-20 BR00117004 CDK2 final crispr F08 A549 144 434 Large +0.29273084479371314 1.252086686241519e-19 BR00117000 TUBB3 final crispr K11 A549 144 509 Large +0.29147518382352944 1.2972638725214137e-19 BR00117000 FOXM1 final crispr A19 A549 144 512 Large +0.33080808080808083 1.4009122053144933e-19 BR00117005 HRH4 final crispr A08 A549 144 396 Large +0.2779148315100164 1.567236895499154e-19 BR00117003 FOXM1 final crispr A19 A549 144 557 Large +0.5048260381593714 1.5710072294763892e-19 BR00117003 TUBB3 final crispr K11 A549 144 162 Large +0.25157748802577534 2.1732863664981193e-19 BR00117001 AURKB final crispr C13 A549 144 682 Large +0.13593651238259158 2.838188568524707e-19 BR00117003 GAA final crispr L17 A549 144 2330 Large +0.3738662391204764 7.272294558748189e-19 BR00117001 RPL3 final crispr K04 A549 144 296 Large +0.3025900928339953 7.678845012237136e-19 BR00117001 TUBB3 final crispr K11 A549 144 455 Large +0.27677753835574936 8.555810247896751e-19 BR00117003 FPR1 final crispr N22 A549 144 541 Large +0.37602124183006536 1.1909548673625281e-18 BR00117005 PPAT final crispr E13 A549 144 288 Large +0.2096705266060105 1.912893463192811e-18 BR00117001 KCNMA1 final crispr A07 A549 144 936 Large +0.12247600256222034 2.297660931977199e-18 BR00117003 PORCN final crispr L13 A549 144 2737 Large +0.334678878869427 3.3991494433137804e-18 BR00117003 CDK4 final crispr P03 A549 144 354 Large +0.22614527717355482 5.105657601549863e-18 BR00117001 JAK1 final crispr J09 A549 144 778 Large +0.22267748021739742 7.221565721176307e-18 BR00117003 CDK7 final crispr E12 A549 144 798 Large +0.22090272995189011 3.232418721547892e-17 BR00117001 ALDH2 final crispr A10 A549 144 779 Large +0.11234267734553775 3.6122402620626454e-17 BR00117003 TUBB4B final crispr J13 A549 144 3036 Large +0.2247654650645305 4.769007988043649e-17 BR00117000 CDK7 final crispr I14 A549 144 749 Large +0.322831104272695 6.923195539316519e-17 BR00117004 PPAT final crispr G13 A549 144 357 Large +0.35295406327829537 7.483924435526619e-17 BR00117000 PLK1 final crispr G09 A549 144 293 Large +0.23793734867536798 1.019737530476305e-16 BR00117003 BRD4 final crispr M19 A549 144 653 Large +0.27141984359726296 1.501889363542025e-16 BR00117003 PRKCE final crispr K05 A549 144 495 Large +0.5291239669421488 2.498363649346381e-16 BR00117003 RPL23A final crispr G14 A549 144 125 Large +0.12565668869309 3.113927848737287e-16 BR00117001 CACNA2D3 final crispr O07 A549 144 2289 Large +0.19432315848398038 3.138785347189444e-16 BR00117003 PPAT final crispr G13 A549 144 954 Large +0.21510062340487845 3.503145189305625e-16 BR00117001 DHH final crispr F05 A549 144 771 Large +0.30665510171897176 4.439757048919873e-16 BR00117005 CDK7 final crispr I14 A549 144 374 Large +0.22396845715008137 4.471921901179115e-16 BR00117003 OPRL1 final crispr A11 A549 144 712 Large +0.23708147812743693 5.086794957573792e-16 BR00117000 CYP2A6 final crispr C07 A549 144 631 Large +0.2611665035953346 8.949752831742868e-16 BR00117003 CA5A final crispr M01 A549 144 508 Large +0.3612167300380228 1.2189590862139137e-15 BR00117005 NAMPT final crispr I09 A549 144 263 Large +0.3697875688434304 1.2264897416082192e-15 BR00117004 CDK9 final crispr M04 A549 144 246 Large +0.34134773807842583 1.3999355388595756e-15 BR00117002 FOXM1 final crispr A19 A549 144 292 Large +0.18855398915835503 1.819869024889741e-15 BR00117000 PPAT final crispr G13 A549 144 964 Large +0.35930232558139535 1.985160807912216e-15 BR00117002 PPAT final crispr E13 A549 144 258 Large +0.2019201772292846 2.440617337607906e-15 BR00117001 CDC25A final crispr D06 A549 144 829 Large +0.3858964741185296 5.897653122141082e-15 BR00117000 PLK1 final crispr F13 A549 144 217 Large +0.32006871747473326 7.790023129455258e-15 BR00117004 GRIN2A final crispr A23 A549 144 314 Large +0.2779234311451716 8.330766906856856e-15 BR00117003 CACNA2D3 final crispr O07 A549 144 422 Large +0.26971478204662064 9.225380480929323e-15 BR00117000 SIRT2 final crispr P01 A549 144 444 Large +0.3276733780760626 1.0342240249360288e-14 BR00117002 HTR3A final crispr O20 A549 144 300 Large +0.18868314006435552 1.3249787847147642e-14 BR00117001 PTPN2 final crispr A15 A549 144 905 Large +0.28790333377962246 1.349164334953673e-14 BR00117003 CDK9 final crispr I20 A549 144 388 Large +0.10433070150814394 1.488251101989612e-14 BR00117004 PORCN final crispr L13 A549 144 2968 Large +0.20786848856986365 1.5248190348842757e-14 BR00117001 HRH4 final crispr A08 A549 144 746 Large +0.42528735632183906 1.7036607121927147e-14 BR00117005 TUBB3 final crispr K11 A549 144 174 Large +0.2872781668593187 1.9509201220775667e-14 BR00117003 CLK1 final crispr M11 A549 144 385 Large +0.34445847443035066 2.084036551154419e-14 BR00117002 SIRT2 final crispr P01 A549 144 266 Large +0.3080972538803864 2.1869914208568177e-14 BR00117005 TUBB4B final crispr C04 A549 144 332 Large +0.20903981710802058 2.6238034776478728e-14 BR00117000 CDK7 final crispr E12 A549 144 724 Large +0.22981928557376127 2.6495251145447722e-14 BR00117003 PARP3 final crispr F12 A549 144 598 Large +0.2735345227062094 2.7386711659217787e-14 BR00117004 CTSG final crispr L12 A549 144 416 Large +0.19579595757181992 2.9917047560506e-14 BR00117000 CDK2 final crispr F08 A549 144 823 Large +0.1281655094697268 3.30590648417794e-14 BR00117001 AGER final crispr J18 A549 144 1918 Large +0.4846153846153846 3.347230166109397e-14 BR00117005 RPL23A final crispr G14 A549 144 130 Large +0.19980964931546966 3.6583422639995105e-14 BR00117001 AKR1C1 final crispr B13 A549 144 785 Large +0.21415581823423743 5.154348050111844e-14 BR00117004 KRAS final crispr F07 A549 144 673 Large +0.7 5.428820713693272e-14 BR00117005 PLK1 final crispr G09 A549 144 55 Large +0.19271701293466711 5.992670590276631e-14 BR00117004 GHSR final crispr A09 A549 144 827 Large +0.27302363488182557 6.031347451550533e-14 BR00117004 CATSPER4 final crispr P02 A549 144 408 Large +0.5618357487922705 6.197902046234754e-14 BR00117005 RPL3 final crispr K04 A549 144 92 Large +0.10841983852364476 9.980891800371485e-14 BR00117004 F10 final crispr H15 A549 144 2601 Large +0.31805669305669304 1.0307432561862494e-13 BR00117003 AVPR1A final crispr J07 A549 144 296 Large +0.23590104948546958 1.0942216702016415e-13 BR00117005 TGFBR1 final crispr B08 A549 144 543 Large +0.5747126436781609 1.2877935918110114e-13 BR00117003 RPL3 final crispr K04 A549 144 87 Large +0.19330855018587362 1.3484765341209732e-13 BR00117005 ASIC1 final crispr M20 A549 144 807 Large +0.24808819999314152 1.6469071214294715e-13 BR00117003 FFAR2 final crispr A24 A549 144 482 Large +0.18366694787432575 1.7257142453433084e-13 BR00117001 MAPK14 final crispr M17 A549 144 885 Large +0.307608786436148 1.9030094214347903e-13 BR00117002 ASIC1 final crispr M20 A549 144 307 Large +0.2931459309387472 2.0872938415874155e-13 BR00117002 CA5A final crispr M01 A549 144 340 Large 0.4204063536124605 7.084071120357091e-32 BR00117000 AURKB final crispr C13 A549 144 396 Metaphase 0.4726847154321557 3.0021048358312815e-30 BR00117000 PLK1 final crispr G09 A549 144 293 Metaphase 0.5773873873873874 1.468569792271002e-23 BR00117005 AURKB final crispr C13 A549 144 150 Metaphase @@ -849,6 +8409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.4426605504587156 9.880735804638588e-20 BR00117004 SIRT2 final crispr P01 A549 144 218 Metaphase 0.4397385060550852 2.7094672349260615e-19 BR00117000 PLK1 final crispr F13 A549 144 217 Metaphase 0.4777542372881356 1.1150027722312501e-18 BR00117004 AURKB final crispr C13 A549 144 176 Metaphase +0.33787974817256095 5.0399014096157176e-18 BR00117001 PLK1 final crispr G09 A549 144 345 Metaphase +0.2409831605042779 7.473904007096386e-18 BR00117001 AURKB final crispr C13 A549 144 682 Metaphase +0.38152638295511293 7.479462907971047e-18 BR00117001 RPL23A final crispr M18 A549 144 269 Metaphase +0.2981651376146789 1.6927524191514297e-17 BR00117004 CDK7 final crispr I14 A549 144 436 Metaphase +0.31319006024964685 8.905575486596172e-17 BR00117000 RPL3 final crispr K04 A549 144 372 Metaphase +0.38042492550848556 1.2649438270629325e-16 BR00117004 TUBB3 final crispr K11 A549 144 248 Metaphase +0.4654320987654321 1.5519441341456057e-16 BR00117003 TUBB3 final crispr K11 A549 144 162 Metaphase +0.2545625976776927 1.9557596039047863e-16 BR00117003 FOXM1 final crispr A19 A549 144 557 Metaphase +0.21433377837116155 1.2033078147046722e-15 BR00117000 CDK7 final crispr I14 A549 144 749 Metaphase +0.26700044580089843 1.2492783385586046e-15 BR00117003 FFAR2 final crispr A24 A549 144 482 Metaphase +0.2483315141909998 3.069715775856114e-15 BR00117001 SLC7A11 final crispr P05 A549 144 541 Metaphase +0.33614292258360057 3.081649838348066e-15 BR00117001 RPL3 final crispr K04 A549 144 296 Metaphase +0.28282915836005895 3.821892008262751e-15 BR00117003 CDK2 final crispr F08 A549 144 415 Metaphase +0.42528735632183906 1.7036607121927147e-14 BR00117005 TUBB3 final crispr K11 A549 144 174 Metaphase +0.28860073652872037 2.376944625666791e-14 BR00117001 RPL23A final crispr G14 A549 144 379 Metaphase +0.2596634272223137 2.7410659872915787e-14 BR00117004 S1PR1 final crispr A18 A549 144 467 Metaphase +0.10225393321419811 3.257751536971421e-14 BR00117004 AKR1B1 final crispr L21 A549 144 3024 Metaphase +0.250760655359219 4.177932684524058e-14 BR00117004 CDC25A final crispr D06 A549 144 491 Metaphase +0.2891891891891892 4.871065361074703e-14 BR00117003 PPAT final crispr E13 A549 144 370 Metaphase +0.09810349053475396 6.063948154109706e-14 BR00117004 AKT1 final crispr J19 A549 144 3225 Metaphase +0.18685015290519877 9.560542108459202e-14 BR00117000 DHH final crispr F05 A549 144 872 Metaphase +0.2887729568953307 1.2545034686131684e-13 BR00117003 CDK4 final crispr P03 A549 144 354 Metaphase +0.20392228567871648 1.3739602770356054e-13 BR00117000 PPAT final crispr E13 A549 144 716 Metaphase +0.20235282911030672 1.5392524424824787e-13 BR00117000 CDK7 final crispr E12 A549 144 724 Metaphase +0.3306196291270918 2.17138712216644e-13 BR00117004 RPL23A final crispr G14 A549 144 268 Metaphase +0.2537316342194391 2.5998608298080995e-13 BR00117001 TUBB3 final crispr K11 A549 144 455 Metaphase +0.3065449402083065 3.29853575001086e-13 BR00117002 HDAC3 final crispr K19 A549 144 303 Metaphase +0.29925254676605917 5.820653534850701e-13 BR00117004 GRIN2A final crispr A23 A549 144 314 Metaphase +0.2830828175655762 7.086371028265591e-13 BR00117004 KCNN1 final crispr D01 A549 144 351 Metaphase +0.23301812807287425 9.174015257401485e-13 BR00117000 CDK4 final crispr B15 A549 144 516 Metaphase +0.3048855905998763 1.2298410509707016e-12 BR00117004 CA5A final crispr M01 A549 144 294 Metaphase +0.2689122807017544 1.6029734564465545e-12 BR00117004 PPAT final crispr E13 A549 144 375 Metaphase +0.3311369000786782 1.851442729479069e-12 BR00117004 CDK9 final crispr M04 A549 144 246 Metaphase +0.19221932799880068 3.0603656148536262e-12 BR00117000 HPGDS final crispr B19 A549 144 731 Metaphase +0.10788871990410907 4.5093223197836736e-12 BR00117001 CACNA2D3 final crispr O07 A549 144 2289 Metaphase +0.17904993909866018 6.53808340686761e-12 BR00117004 CDK7 final crispr E12 A549 144 821 Metaphase +0.0939111674965501 7.133850354319145e-12 BR00117004 PORCN final crispr L13 A549 144 2968 Metaphase +0.2500089015488695 7.34879653875097e-12 BR00117003 SLC7A11 final crispr P05 A549 144 411 Metaphase +0.24423963133640553 9.0408553008529e-12 BR00117004 CDK2 final crispr F08 A549 144 434 Metaphase +0.16116116116116116 9.746145889696312e-12 BR00117004 F10 final crispr H07 A549 144 999 Metaphase +0.2 1.3080349922789511e-11 BR00117004 TUBB4B final crispr C04 A549 144 640 Metaphase +0.2644628099173554 1.4402569599368768e-11 BR00117004 FOXM1 final crispr A19 A549 144 363 Metaphase +0.4619190404797601 1.473063389482183e-11 BR00117002 AURKB final crispr C13 A549 144 115 Metaphase +0.23383210991906644 1.6293568507750842e-11 BR00117005 CDK7 final crispr E12 A549 144 460 Metaphase +0.6681465038845728 1.7649000855046957e-11 BR00117002 RPL23A final crispr M18 A549 144 51 Metaphase +0.5287356321839081 1.7858799042388578e-11 BR00117003 RPL3 final crispr K04 A549 144 87 Metaphase +0.25409023965724997 1.9070080887176826e-11 BR00117003 CDK9 final crispr I20 A549 144 388 Metaphase +0.24257447928921158 2.1251096242718393e-11 BR00117003 CACNA2D3 final crispr O07 A549 144 422 Metaphase +0.17461169679514305 2.8861540365794694e-11 BR00117004 TNNC1 final crispr D09 A549 144 811 Metaphase +0.22585710667495568 5.7253057300185935e-11 BR00117005 SLC7A11 final crispr P05 A549 144 465 Metaphase +0.10067343125782567 6.263245253889905e-11 BR00117003 IL1B final crispr H18 A549 144 2370 Metaphase +0.49415204678362573 8.040888329993324e-11 BR00117002 TUBB3 final crispr K11 A549 144 95 Metaphase +0.214859068627451 8.641551143584253e-11 BR00117000 FOXM1 final crispr A19 A549 144 512 Metaphase +0.1798455858928471 9.259454533833235e-11 BR00117000 TGFBR1 final crispr B08 A549 144 731 Metaphase +0.09717694204348164 1.0802258247379839e-10 BR00117005 PTK2B final crispr N15 A549 144 2494 Metaphase +0.17396907216494845 1.1372439923490657e-10 BR00117004 FGF1 final crispr J12 A549 144 776 Metaphase +0.21668164614889882 1.184829678898288e-10 BR00117004 OPRL1 final crispr A11 A549 144 491 Metaphase +0.2802820239364854 1.69564038369634e-10 BR00117002 CDK9 final crispr I20 A549 144 291 Metaphase +0.21975813784324422 1.9253311294084722e-10 BR00117003 PARP3 final crispr L11 A549 144 470 Metaphase +0.486231884057971 1.9281388409053698e-10 BR00117005 RPL3 final crispr K04 A549 144 92 Metaphase +0.2324490268767377 2.0705979255261648e-10 BR00117004 CTSG final crispr L12 A549 144 416 Metaphase +0.19376026272577998 2.0733269865764872e-10 BR00117004 PTPN2 final crispr B12 A549 144 609 Metaphase +0.17254901960784313 2.3238943725460078e-10 BR00117000 HDAC3 final crispr K19 A549 144 765 Metaphase +0.42168595041322315 2.4985637841322373e-10 BR00117003 RPL23A final crispr G14 A549 144 125 Metaphase +0.2705243730322441 2.8319057810591943e-10 BR00117004 CDK4 final crispr P03 A549 144 302 Metaphase +0.2124248496993988 2.864971419102073e-10 BR00117004 TGFBR1 final crispr B08 A549 144 499 Metaphase +0.21261404366243075 3.009991111446693e-10 BR00117003 PRKCE final crispr K05 A549 144 495 Metaphase +0.18672975352112675 3.449346275721551e-10 BR00117004 CACNB4 final crispr B01 A549 144 639 Metaphase +0.24267902081903456 3.668047408116066e-10 BR00117004 CDK4 final crispr B15 A549 144 372 Metaphase +0.15343915343915343 4.031321628370686e-10 BR00117000 ATP5F1D final crispr G21 A549 144 945 Metaphase +0.25970859696987286 4.946987457927345e-10 BR00117004 CDK9 final crispr I20 A549 144 322 Metaphase +0.23931283855475513 5.107075717210192e-10 BR00117004 SLC7A11 final crispr P05 A549 144 376 Metaphase +0.23484848484848486 5.47996107261765e-10 BR00117005 HRH4 final crispr A08 A549 144 396 Metaphase +0.18385687215980084 5.567487459246785e-10 BR00117000 COMT final crispr A12 A549 144 643 Metaphase +0.15787147458997136 6.307826926257607e-10 BR00117004 BRAF final crispr F20 A549 144 869 Metaphase +0.26366559485530544 6.531654449694417e-10 BR00117005 HDAC3 final crispr K19 A549 144 311 Metaphase +0.18778701983902663 7.445825544956615e-10 BR00117003 RGS4 final crispr N11 A549 144 609 Metaphase +0.2261904761904762 7.925257070767523e-10 BR00117004 HRH4 final crispr A08 A549 144 420 Metaphase +0.27174644367550943 8.112663941646375e-10 BR00117005 PPAT final crispr E13 A549 144 288 Metaphase +0.1853594832452738 8.85314408175086e-10 BR00117003 ADRA2B final crispr J14 A549 144 619 Metaphase +0.1713635315813739 9.449853220740333e-10 BR00117003 SLC29A1 final crispr E03 A549 144 723 Metaphase +0.16019417475728157 1.212147296522129e-09 BR00117004 BRD4 final crispr M19 A549 144 824 Metaphase +0.16209476309226933 1.3023096468947544e-09 BR00117000 F10 final crispr H07 A549 144 802 Metaphase +0.2515856835428701 1.400383820036751e-09 BR00117003 ATP5F1D final crispr E15 A549 144 327 Metaphase +0.1846217525076229 1.8586235951803038e-09 BR00117004 BRD4 final crispr J16 A549 144 605 Metaphase +0.18270437753237467 2.0567202127851235e-09 BR00117003 TUBB final crispr K13 A549 144 614 Metaphase +0.1937752542015162 2.135639751785427e-09 BR00117003 FPR1 final crispr N22 A549 144 541 Metaphase +0.08086542427153379 2.47796352421411e-09 BR00117004 S100B final crispr D22 A549 144 3123 Metaphase +0.3923076923076923 2.5711568605498353e-09 BR00117005 RPL23A final crispr G14 A549 144 130 Metaphase +0.1503233824536485 3.1182286421582673e-09 BR00117004 IMPDH1 final crispr G05 A549 144 886 Metaphase 0.15687988766861585 4.6969256902253524e-27 BR00117005 LPAR1 final crispr L01 A549 144 2470 MetaphaseAlignment 0.13290983626253744 2.4728377930120507e-25 BR00117004 AKT1 final crispr J19 A549 144 3225 MetaphaseAlignment 0.11854830232313676 5.649890438939739e-19 BR00117004 AKR1B1 final crispr L21 A549 144 3024 MetaphaseAlignment @@ -859,6 +8509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.11572472126105345 1.3872933974347715e-15 BR00117004 F10 final crispr H15 A549 144 2601 MetaphaseAlignment 0.19169329073482427 1.7012348156953907e-15 BR00117000 TUBB4B final crispr C04 A549 144 939 MetaphaseAlignment 0.11686868234867656 2.8362989659053478e-15 BR00117005 PTK2B final crispr N15 A549 144 2494 MetaphaseAlignment +0.29689526939375593 4.187361418597818e-15 BR00117000 RPL3 final crispr K04 A549 144 372 MetaphaseAlignment +0.12051820560255008 5.855072056741447e-15 BR00117001 CACNA2D3 final crispr O07 A549 144 2289 MetaphaseAlignment +0.27522935779816515 6.132511291036447e-15 BR00117004 CDK7 final crispr I14 A549 144 436 MetaphaseAlignment +0.10882262769188432 1.507946191337132e-14 BR00117003 PORCN final crispr L13 A549 144 2737 MetaphaseAlignment +0.13841454917955612 4.156354697017202e-14 BR00117001 PTK2B final crispr N15 A549 144 1629 MetaphaseAlignment +0.10255385611901628 5.1247086805215926e-14 BR00117004 PORCN final crispr L13 A549 144 2968 MetaphaseAlignment +0.3721542643560992 7.534966065311762e-14 BR00117004 SIRT2 final crispr P01 A549 144 218 MetaphaseAlignment +0.1158643911116844 8.669612668773535e-14 BR00117005 PDPK1 final crispr N18 A549 144 2282 MetaphaseAlignment +0.4181726907630522 1.5121785980457484e-13 BR00117000 RPL23A final crispr M18 A549 144 166 MetaphaseAlignment +0.3036126906307139 2.0789567503157698e-13 BR00117004 GRIN2A final crispr A23 A549 144 314 MetaphaseAlignment +0.12963261280187288 3.1539371915945754e-13 BR00117001 LPAR1 final crispr L01 A549 144 1739 MetaphaseAlignment +0.27427123471268217 4.674972298843005e-13 BR00117004 SLC7A11 final crispr P05 A549 144 376 MetaphaseAlignment +0.2375249500998004 6.484576657855897e-13 BR00117004 KCNN4 final crispr K01 A549 144 504 MetaphaseAlignment +0.09696536301227376 6.919397711157187e-13 BR00117003 TUBB4B final crispr J13 A549 144 3036 MetaphaseAlignment +0.2450447482567397 6.951717365476909e-13 BR00117004 S1PR1 final crispr A18 A549 144 467 MetaphaseAlignment +0.19390685754683634 1.4000871548292914e-12 BR00117004 GHSR final crispr B20 A549 144 738 MetaphaseAlignment +0.20342071116907914 1.4850336611185289e-12 BR00117004 FPR1 final crispr N22 A549 144 669 MetaphaseAlignment +0.11470591419873281 1.573451038895181e-12 BR00117005 AKR1B1 final crispr L21 A549 144 2107 MetaphaseAlignment +0.1925985902076586 2.865203708732737e-12 BR00117000 CDK7 final crispr E12 A549 144 724 MetaphaseAlignment +0.2341484195279884 4.205908356945768e-12 BR00117004 HIF1A final crispr M24 A549 144 485 MetaphaseAlignment +0.19281531887956954 4.474397181096869e-12 BR00117004 HIF1A final crispr A01 A549 144 710 MetaphaseAlignment +0.17904993909866018 6.53808340686761e-12 BR00117004 CDK7 final crispr E12 A549 144 821 MetaphaseAlignment +0.29600590351443595 7.09806663303957e-12 BR00117000 PLK1 final crispr G09 A549 144 293 MetaphaseAlignment +0.1042515765477496 7.218632487764546e-12 BR00117004 KRAS final crispr D21 A549 144 2404 MetaphaseAlignment +0.11470688449782816 7.703513980275025e-12 BR00117004 MET final crispr H13 A549 144 1991 MetaphaseAlignment +0.1539855072463768 7.800450884309108e-12 BR00117000 AKT1 final crispr F06 A549 144 1104 MetaphaseAlignment +0.18286397377546598 9.736551999348263e-12 BR00117000 KCNJ1 final crispr E14 A549 144 768 MetaphaseAlignment +0.10207646579570584 9.888703311121447e-12 BR00117004 RPL3 final crispr H11 A549 144 2481 MetaphaseAlignment +0.17643962522370776 1.0427257967980409e-11 BR00117004 BTK final crispr D24 A549 144 828 MetaphaseAlignment +0.19772619812139647 1.2887948283800799e-11 BR00117004 OPRL1 final crispr A04 A549 144 653 MetaphaseAlignment +0.2 1.3080349922789511e-11 BR00117004 TUBB4B final crispr C04 A549 144 640 MetaphaseAlignment +0.10397468710648977 1.394639248197495e-11 BR00117003 IL1B final crispr H18 A549 144 2370 MetaphaseAlignment +0.18156758495741546 1.4614855905178005e-11 BR00117004 KCNMA1 final crispr E23 A549 144 770 MetaphaseAlignment +0.17597087378640777 1.474299787208031e-11 BR00117003 TUBB4B final crispr C04 A549 144 824 MetaphaseAlignment +0.22466749672237935 2.031466161783166e-11 BR00117004 OPRL1 final crispr A11 A549 144 491 MetaphaseAlignment +0.09965416334131418 2.560944432511732e-11 BR00117003 AKT1 final crispr J19 A549 144 2505 MetaphaseAlignment +0.16824678832475248 3.212267384851303e-11 BR00117004 BRAF final crispr F20 A549 144 869 MetaphaseAlignment +0.25364912280701757 3.4767283382642134e-11 BR00117004 PPAT final crispr E13 A549 144 375 MetaphaseAlignment +0.2402706070856329 5.5296537990847263e-11 BR00117003 SLC7A11 final crispr P05 A549 144 411 MetaphaseAlignment +0.15770342033476992 6.023320802230447e-11 BR00117000 TUBB final crispr K13 A549 144 963 MetaphaseAlignment +0.18347338935574228 6.468773926966634e-11 BR00117004 FFAR2 final crispr A24 A549 144 714 MetaphaseAlignment +0.11666417844388749 8.839492351030333e-11 BR00117001 CACNG1 final crispr N23 A549 144 1738 MetaphaseAlignment +0.1901840490797546 1.0103774469389984e-10 BR00117000 IMPDH1 final crispr F15 A549 144 652 MetaphaseAlignment +0.09404283464496373 1.0198287005544542e-10 BR00117004 AGER final crispr J18 A549 144 2673 MetaphaseAlignment +0.17997349008759797 1.0230099596011607e-10 BR00117003 SLC29A1 final crispr E03 A549 144 723 MetaphaseAlignment +0.09427672955974843 1.0589838377296927e-10 BR00117003 CACNG1 final crispr N23 A549 144 2650 MetaphaseAlignment +0.20998044747151898 1.0642460758531509e-10 BR00117004 TUBB final crispr K13 A549 144 526 MetaphaseAlignment +0.26887057138987247 1.1126799536189271e-10 BR00117004 CDK9 final crispr I20 A549 144 322 MetaphaseAlignment +0.16322102710112835 1.215316389535247e-10 BR00117000 DHH final crispr F05 A549 144 872 MetaphaseAlignment +0.17136936100753733 1.3406835907118654e-10 BR00117000 AKR1C1 final crispr B13 A549 144 791 MetaphaseAlignment +0.11914893617021277 1.3735279919538512e-10 BR00117001 RGS4 final crispr N11 A549 144 1645 MetaphaseAlignment +0.2227011223238706 1.5020715848300213e-10 BR00117004 USP1 final crispr N12 A549 144 460 MetaphaseAlignment +0.2889918437552017 1.7286985123744043e-10 BR00117001 RPL23A final crispr M18 A549 144 269 MetaphaseAlignment +0.23345179278264136 1.753213965551457e-10 BR00117003 TBXAS1 final crispr P08 A549 144 415 MetaphaseAlignment +0.19349593495934958 1.7615077225176877e-10 BR00117003 CACNA2D3 final crispr N24 A549 144 615 MetaphaseAlignment +0.17914741696751627 1.96208796218795e-10 BR00117003 HDAC3 final crispr K19 A549 144 707 MetaphaseAlignment +0.09482447165548782 2.2393483719543038e-10 BR00117004 ELANE final crispr N19 A549 144 2527 MetaphaseAlignment +0.11173878548893938 3.252098949961624e-10 BR00117004 AKR1B1 final crispr H17 A549 144 1791 MetaphaseAlignment +0.2114300903774588 3.2614286909483113e-10 BR00117004 HCK final crispr M23 A549 144 494 MetaphaseAlignment +0.08461761127121357 3.3800638215302417e-10 BR00117004 S100B final crispr D22 A549 144 3123 MetaphaseAlignment +0.16708229426433915 3.4513658032665954e-10 BR00117000 F10 final crispr H07 A549 144 802 MetaphaseAlignment +0.10788378348309238 3.6908408895207156e-10 BR00117000 LPAR1 final crispr L01 A549 144 1916 MetaphaseAlignment +0.23834196891191708 4.994222394221662e-10 BR00117005 CDC25A final crispr C14 A549 144 386 MetaphaseAlignment +0.10232710788242663 6.586434378014692e-10 BR00117004 CCND1 final crispr O05 A549 144 2071 MetaphaseAlignment +0.206286836935167 6.850426687952429e-10 BR00117000 TUBB3 final crispr K11 A549 144 509 MetaphaseAlignment +0.10801723907321663 6.976556028941076e-10 BR00117004 AVPR1A final crispr J07 A549 144 1852 MetaphaseAlignment +0.31109205872896795 7.940512372614545e-10 BR00117000 PLK1 final crispr F13 A549 144 217 MetaphaseAlignment +0.16688227684346701 8.200923482728013e-10 BR00117000 IGF1R final crispr E19 A549 144 773 MetaphaseAlignment +0.13971388897213813 8.328907523671541e-10 BR00117000 MMP2 final crispr D14 A549 144 1094 MetaphaseAlignment +0.19977301744928358 8.737703585024083e-10 BR00117004 ADORA2A final crispr B22 A549 144 530 MetaphaseAlignment +0.20348837209302326 9.24328843764363e-10 BR00117005 PTGIR final crispr G10 A549 144 516 MetaphaseAlignment +0.15533297601500737 9.386210507486565e-10 BR00117004 PRKCE final crispr I17 A549 144 878 MetaphaseAlignment +0.3569023569023569 9.421467449093753e-10 BR00117003 TUBB3 final crispr K11 A549 144 162 MetaphaseAlignment +0.1703989655753987 9.92810137582679e-10 BR00117000 HPGDS final crispr B19 A549 144 731 MetaphaseAlignment +0.09836211060481735 1.0678626853760536e-09 BR00117005 GAA final crispr L17 A549 144 2191 MetaphaseAlignment +0.26483301483301486 1.128584051867504e-09 BR00117003 AVPR1A final crispr J07 A549 144 296 MetaphaseAlignment +0.22682926829268293 1.1769839936221193e-09 BR00117003 CDK9 final crispr M04 A549 144 410 MetaphaseAlignment +0.16470084254443 1.2764545715858045e-09 BR00117000 NAMPT final crispr I09 A549 144 768 MetaphaseAlignment +0.09800236321926292 1.2828549187546767e-09 BR00117003 HSP90AB1 final crispr B04 A549 144 2198 MetaphaseAlignment +0.10576665573086325 1.374309881270134e-09 BR00117005 LYN final crispr N13 A549 144 1874 MetaphaseAlignment +0.19389587073608616 1.4355962253038699e-09 BR00117004 PTPN2 final crispr A15 A549 144 557 MetaphaseAlignment +0.1709029854160823 1.5558726182493661e-09 BR00117004 FFAR4 final crispr G11 A549 144 707 MetaphaseAlignment +0.18241462646885137 1.5873004134835984e-09 BR00117003 ADRA2B final crispr J14 A549 144 619 MetaphaseAlignment +0.10509554140127389 1.7763698060294815e-09 BR00117003 BTK final crispr P17 A549 144 1884 MetaphaseAlignment +0.17372262773722627 1.9222095794463195e-09 BR00117004 HSD11B1 final crispr O23 A549 144 685 MetaphaseAlignment +0.22142857142857142 1.9679694557352307e-09 BR00117004 HRH4 final crispr A08 A549 144 420 MetaphaseAlignment +0.09416758652334715 2.0176391388860946e-09 BR00117003 GAA final crispr L17 A549 144 2330 MetaphaseAlignment +0.22727272727272727 2.2446067590581095e-09 BR00117005 HRH4 final crispr A08 A549 144 396 MetaphaseAlignment +0.09656339871017448 2.2884923795772165e-09 BR00117005 ELANE final crispr N19 A549 144 2192 MetaphaseAlignment +0.26162391204764085 2.4261165748479564e-09 BR00117001 RPL3 final crispr K04 A549 144 296 MetaphaseAlignment 0.20755922086535272 2.9888240289913147e-61 BR00117004 AKT1 final crispr J19 A549 144 3225 OutOfFocus 0.2245607845018329 1.2714121990190055e-55 BR00117005 PTK2B final crispr N15 A549 144 2494 OutOfFocus 0.2208001481148939 3.248310699310972e-53 BR00117005 LPAR1 final crispr L01 A549 144 2470 OutOfFocus @@ -869,6 +8609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.17356185434986768 2.1246815225633902e-35 BR00117003 CACNG1 final crispr N23 A549 144 2650 OutOfFocus 0.15746571886007044 3.122093359114203e-34 BR00117004 S100B final crispr D22 A549 144 3123 OutOfFocus 0.1591694698482778 7.0229661821332705e-34 BR00117004 AKR1B1 final crispr L21 A549 144 3024 OutOfFocus +0.44450690420594424 7.3575480741879685e-34 BR00117000 RPL3 final crispr K04 A549 144 372 OutOfFocus +0.1804974412934874 1.3557866544716123e-33 BR00117003 GAA final crispr L17 A549 144 2330 OutOfFocus +0.18231363283143934 2.2611001553313015e-32 BR00117005 ELANE final crispr N19 A549 144 2192 OutOfFocus +0.4036697247706422 3.862776658418825e-32 BR00117004 CDK7 final crispr I14 A549 144 436 OutOfFocus +0.20212207969623425 1.466141460142479e-31 BR00117001 CACNG1 final crispr N23 A549 144 1738 OutOfFocus +0.16742317440139673 4.165983006361288e-31 BR00117003 AKT1 final crispr J19 A549 144 2505 OutOfFocus +0.17574796587774974 9.324029523202478e-28 BR00117000 CACNA2D3 final crispr O07 A549 144 2018 OutOfFocus +0.15417147251057287 2.236568492133145e-27 BR00117004 F10 final crispr H15 A549 144 2601 OutOfFocus +0.18710523553330793 3.745139063946639e-27 BR00117001 LPAR1 final crispr L01 A549 144 1739 OutOfFocus +0.17458437226632462 5.31585594588007e-26 BR00117000 LPAR1 final crispr L01 A549 144 1916 OutOfFocus +0.2470713525026624 1.4488886608880977e-25 BR00117000 TUBB4B final crispr C04 A549 144 939 OutOfFocus +0.46510234486332425 5.070507565974623e-25 BR00117004 TUBB3 final crispr K11 A549 144 248 OutOfFocus +0.49689942235813794 8.743668074825534e-25 BR00117004 SIRT2 final crispr P01 A549 144 218 OutOfFocus +0.3280943025540275 1.2121375738385668e-24 BR00117000 TUBB3 final crispr K11 A549 144 509 OutOfFocus +0.4110791858385742 1.657020696719607e-24 BR00117004 GRIN2A final crispr A23 A549 144 314 OutOfFocus +0.14277099560699028 2.918981026148459e-24 BR00117004 AGER final crispr J18 A549 144 2673 OutOfFocus +0.1526893707750346 1.0716079475861142e-23 BR00117005 PDPK1 final crispr N18 A549 144 2282 OutOfFocus +0.33292348783127257 1.6916528538178376e-23 BR00117005 SLC7A11 final crispr P05 A549 144 465 OutOfFocus +0.15824131403379285 1.850476306080563e-23 BR00117005 AKR1B1 final crispr L21 A549 144 2107 OutOfFocus +0.33036841816285073 5.028806099008058e-23 BR00117004 S1PR1 final crispr A18 A549 144 467 OutOfFocus +0.24847746650426308 1.1706271479779005e-22 BR00117004 CDK7 final crispr E12 A549 144 821 OutOfFocus +0.3707635009310987 1.3778160906502262e-22 BR00117000 RPL23A final crispr G14 A549 144 358 OutOfFocus +0.1536654135338346 2.4936054403659275e-22 BR00117003 HCK final crispr H23 A549 144 2128 OutOfFocus +0.3589587870665103 3.0991231160477315e-22 BR00117004 SLC7A11 final crispr P05 A549 144 376 OutOfFocus +0.40420293174530464 5.173843195055885e-22 BR00117001 RPL3 final crispr K04 A549 144 296 OutOfFocus +0.41911723908339343 9.35647645735563e-22 BR00117001 RPL23A final crispr M18 A549 144 269 OutOfFocus +0.15922716867898248 9.74169087398799e-22 BR00117001 AGER final crispr J18 A549 144 1918 OutOfFocus +0.35112280701754384 3.399111404577912e-21 BR00117004 PPAT final crispr E13 A549 144 375 OutOfFocus +0.1598363118452907 3.607403960163606e-21 BR00117001 SLC29A1 final crispr N21 A549 144 1860 OutOfFocus +0.3078118686972798 3.6320003081428324e-21 BR00117004 OPRL1 final crispr A11 A549 144 491 OutOfFocus +0.15822784810126583 4.021577446211036e-21 BR00117000 AKR1B1 final crispr L21 A549 144 1896 OutOfFocus +0.22328042328042327 4.765239583019625e-21 BR00117000 ATP5F1D final crispr G21 A549 144 945 OutOfFocus +0.14344565366644343 5.352791972303214e-21 BR00117003 LPAR1 final crispr L01 A549 144 2283 OutOfFocus +0.3383838383838384 1.741209404526048e-20 BR00117005 HRH4 final crispr A08 A549 144 396 OutOfFocus +0.34542068206510235 1.8718670060187463e-20 BR00117001 RPL23A final crispr G14 A549 144 379 OutOfFocus +0.14402156468639715 2.4714825561925263e-20 BR00117003 HSP90AB1 final crispr B04 A549 144 2198 OutOfFocus +0.265625 2.9404792804952706e-20 BR00117004 TUBB4B final crispr C04 A549 144 640 OutOfFocus +0.2523155501572768 5.737458745012965e-20 BR00117004 HDAC3 final crispr K19 A549 144 693 OutOfFocus +0.23566084788029926 6.121477331067377e-20 BR00117000 F10 final crispr H07 A549 144 802 OutOfFocus +0.2573578681511262 6.69460524814106e-20 BR00117004 FPR1 final crispr N22 A549 144 669 OutOfFocus +0.16470302455117558 1.0087621336326733e-19 BR00117001 PTK2B final crispr N15 A549 144 1629 OutOfFocus +0.28245817380637794 1.2670137718300803e-19 BR00117001 SLC7A11 final crispr P05 A549 144 541 OutOfFocus +0.12932767065662962 1.2703978724925544e-19 BR00117004 MAPK8 final crispr D13 A549 144 2632 OutOfFocus +0.1522212663660363 1.9869565084531468e-19 BR00117005 LYN final crispr N13 A549 144 1874 OutOfFocus +0.14035895075931892 4.486393897788229e-19 BR00117000 SLC29A1 final crispr N21 A549 144 2173 OutOfFocus +0.13170731707317074 5.225776962056196e-19 BR00117004 TUBB final crispr J17 A549 144 2460 OutOfFocus +0.28918637274549097 7.439900855356681e-19 BR00117004 DHH final crispr F05 A549 144 500 OutOfFocus +0.23285899094437257 8.742999398400203e-19 BR00117000 IGF1R final crispr E19 A549 144 773 OutOfFocus +0.3142857142857143 9.94468812521201e-19 BR00117004 HRH4 final crispr A08 A549 144 420 OutOfFocus +0.2552254573817916 1.162717961104618e-18 BR00117000 FFAR2 final crispr A24 A549 144 636 OutOfFocus +0.4858720596672404 1.4228625673668238e-18 BR00117000 RPL23A final crispr M18 A549 144 166 OutOfFocus +0.1355325000594441 1.889685648026549e-18 BR00117003 PDE3A final crispr O08 A549 144 2248 OutOfFocus +0.1310367920378019 3.441093018608544e-18 BR00117003 IL1B final crispr H18 A549 144 2370 OutOfFocus +0.2909304002884962 4.1866303083045785e-18 BR00117004 SSTR2 final crispr P10 A549 144 470 OutOfFocus +0.21816037735849056 4.384081537009165e-18 BR00117000 HRH4 final crispr A08 A549 144 848 OutOfFocus +0.22789921942464314 5.642920079763861e-18 BR00117004 KCNMA1 final crispr E23 A549 144 770 OutOfFocus +0.3497610340357191 6.748008924358057e-18 BR00117004 CDK9 final crispr I20 A549 144 322 OutOfFocus +0.1353348729792148 1.0738786260165438e-17 BR00117000 ELANE final crispr N19 A549 144 2165 OutOfFocus +0.24539877300613497 1.2219359455937913e-17 BR00117000 IMPDH1 final crispr F15 A549 144 652 OutOfFocus +0.18999073215940684 1.9534654313368954e-17 BR00117000 FPR1 final crispr I18 A549 144 1079 OutOfFocus +0.2244324338968357 1.977168141586996e-17 BR00117000 KCNJ1 final crispr E14 A549 144 768 OutOfFocus +0.3575895004466433 2.2111454950420665e-17 BR00117004 CA5A final crispr M01 A549 144 294 OutOfFocus +0.2883116883116883 2.3634000813161623e-17 BR00117005 CDK7 final crispr E12 A549 144 460 OutOfFocus +0.28126607455162717 2.784982815345498e-17 BR00117003 FFAR2 final crispr A24 A549 144 482 OutOfFocus +0.24306160426821427 3.589866004054846e-17 BR00117000 COMT final crispr A12 A549 144 643 OutOfFocus +0.24457395498392284 6.740494371739541e-17 BR00117004 ATP5F1D final crispr G21 A549 144 622 OutOfFocus +0.14042189131848426 7.31761981267728e-17 BR00117000 NTRK1 final crispr P07 A549 144 1912 OutOfFocus +0.12419564066818642 1.1539390123277473e-16 BR00117004 KRAS final crispr D21 A549 144 2404 OutOfFocus +0.1360058450189699 1.4019070316366132e-16 BR00117000 LYN final crispr N13 A549 144 1995 OutOfFocus +0.21385400091823323 1.7780676604937188e-16 BR00117000 ICAM1 final crispr C20 A549 144 799 OutOfFocus +0.2207832665776591 1.7867320413484783e-16 BR00117000 CDK7 final crispr I14 A549 144 749 OutOfFocus +0.21049723352020813 1.7900771674357983e-16 BR00117004 GHSR final crispr A09 A549 144 827 OutOfFocus +0.22424504379898572 1.9538843806980394e-16 BR00117003 SLC29A1 final crispr E03 A549 144 723 OutOfFocus +0.22549019607843138 2.5666023936744253e-16 BR00117004 FFAR2 final crispr A24 A549 144 714 OutOfFocus +0.2244907486655981 2.595021830792295e-16 BR00117000 PPAT final crispr E13 A549 144 716 OutOfFocus +0.3412412669838412 2.7799297468964433e-16 BR00117002 HDAC3 final crispr K19 A549 144 303 OutOfFocus +0.21663686605981794 2.844058238148275e-16 BR00117000 NAMPT final crispr I09 A549 144 768 OutOfFocus +0.20171048969789424 3.5934506397113976e-16 BR00117004 PRKCE final crispr I17 A549 144 878 OutOfFocus +0.37614739050616314 4.952343703977197e-16 BR00117004 CDK9 final crispr M04 A549 144 246 OutOfFocus +0.3514639071176174 5.315745754140776e-16 BR00117005 COMT final crispr A12 A549 144 280 OutOfFocus +0.21568627450980393 5.413437344871798e-16 BR00117000 HDAC3 final crispr K19 A549 144 765 OutOfFocus +0.28440366972477066 6.166244619487528e-16 BR00117004 DYRK1B final crispr N16 A549 144 436 OutOfFocus +0.3159691521760487 6.411595308054884e-16 BR00117004 KCNN1 final crispr D01 A549 144 351 OutOfFocus +0.2009754297163345 6.686282752374758e-16 BR00117000 DHH final crispr F05 A549 144 872 OutOfFocus +0.31176526131910676 8.01893946142444e-16 BR00117003 CDK4 final crispr P03 A549 144 354 OutOfFocus +0.20631067961165048 9.302562952742318e-16 BR00117004 BRD4 final crispr M19 A549 144 824 OutOfFocus +0.21073874074486446 9.419339580873773e-16 BR00117001 AVPR1A final crispr J07 A549 144 781 OutOfFocus +0.11878987514128724 1.0792153763053386e-15 BR00117004 RPL3 final crispr H11 A549 144 2481 OutOfFocus +0.233974794355143 1.1671822225658156e-15 BR00117000 CYP2A6 final crispr C07 A549 144 631 OutOfFocus +0.3763502985100758 1.3514811112862614e-15 BR00117005 ATP5F1D final crispr E15 A549 144 237 OutOfFocus 0.22083176998936652 2.383828354415497e-53 BR00117005 LPAR1 final crispr L01 A549 144 2470 Polylobed 0.15527456034476425 3.2815198099784605e-29 BR00117003 PORCN final crispr L13 A549 144 2737 Polylobed 0.15944988164287988 4.170890680706672e-28 BR00117005 PTK2B final crispr N15 A549 144 2494 Polylobed @@ -879,6 +8709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.22470713525026625 3.5002463231572166e-21 BR00117000 TUBB4B final crispr C04 A549 144 939 Polylobed 0.14685297848741058 4.030159576960142e-21 BR00117005 ELANE final crispr N19 A549 144 2192 Polylobed 0.25936445648675865 5.090573534299202e-21 BR00117004 HDAC3 final crispr K19 A549 144 693 Polylobed +0.14849624060150377 7.097711171377756e-21 BR00117003 HCK final crispr H23 A549 144 2128 Polylobed +0.1362873614303715 9.968521597850976e-21 BR00117003 AKT1 final crispr J19 A549 144 2505 Polylobed +0.11670220511753693 1.764267347774724e-18 BR00117003 TUBB4B final crispr J13 A549 144 3036 Polylobed +0.13717129363682712 1.869126973978546e-18 BR00117003 HSP90AB1 final crispr B04 A549 144 2198 Polylobed +0.12480890179003387 1.9858360083686764e-18 BR00117003 CACNG1 final crispr N23 A549 144 2650 Polylobed +0.13238705658026392 4.542601440070826e-18 BR00117003 CHRM3 final crispr B17 A549 144 2300 Polylobed +0.1517851126768565 5.689161918075297e-18 BR00117001 CACNG1 final crispr N23 A549 144 1738 Polylobed +0.3926512501619381 8.936369803234445e-18 BR00117004 TUBB3 final crispr K11 A549 144 248 Polylobed +0.13944726040206604 9.388750559465893e-18 BR00117003 LYN final crispr N13 A549 144 2038 Polylobed +0.24375 4.2927278423827394e-17 BR00117004 TUBB4B final crispr C04 A549 144 640 Polylobed +0.15129836137191321 8.959657825937468e-17 BR00117001 PTK2B final crispr N15 A549 144 1629 Polylobed +0.1439363979853024 3.3715125767610835e-16 BR00117001 LPAR1 final crispr L01 A549 144 1739 Polylobed +0.3342542546565131 4.038658909638013e-16 BR00117004 GRIN2A final crispr A23 A549 144 314 Polylobed +0.13676284841067793 4.649638186629755e-16 BR00117000 LPAR1 final crispr L01 A549 144 1916 Polylobed +0.30730202657903083 5.285065976535043e-16 BR00117000 RPL3 final crispr K04 A549 144 372 Polylobed +0.10656522574447647 6.909721767315897e-16 BR00117004 S100B final crispr D22 A549 144 3123 Polylobed +0.1284580548993848 1.332609796584189e-15 BR00117005 AKR1B1 final crispr L21 A549 144 2107 Polylobed +0.2705855264672699 1.4357809343223167e-15 BR00117005 SLC7A11 final crispr P05 A549 144 465 Polylobed +0.2193661971830986 1.8082759107423463e-15 BR00117004 HIF1A final crispr A01 A549 144 710 Polylobed +0.23291285349163163 2.295633297717458e-15 BR00117004 ATP5F1D final crispr G21 A549 144 622 Polylobed +0.20052403176942601 5.355093415782987e-15 BR00117004 BTK final crispr D24 A549 144 828 Polylobed +0.11341791618608228 5.5179525614328846e-15 BR00117004 F10 final crispr H15 A549 144 2601 Polylobed +0.1330681637914222 5.9512436977221714e-15 BR00117005 LYN final crispr N13 A549 144 1874 Polylobed +0.11952927908420972 6.208322746095787e-15 BR00117003 GAA final crispr L17 A549 144 2330 Polylobed +0.2115662189230588 6.589777053795241e-15 BR00117004 GHSR final crispr B20 A549 144 738 Polylobed +0.10472817898314588 6.862635370059473e-15 BR00117004 AKR1B1 final crispr L21 A549 144 3024 Polylobed +0.12883538500038355 7.221693408959504e-15 BR00117000 LYN final crispr N13 A549 144 1995 Polylobed +0.20024271844660194 7.300236917414664e-15 BR00117003 TUBB4B final crispr C04 A549 144 824 Polylobed +0.20615655530909768 8.986598174552762e-15 BR00117004 KCNMA1 final crispr E23 A549 144 770 Polylobed +0.4353126792885829 1.0271272992714342e-14 BR00117000 RPL23A final crispr M18 A549 144 166 Polylobed +0.1162343772160744 1.3296451991028188e-14 BR00117004 KRAS final crispr D21 A549 144 2404 Polylobed +0.23063285263266808 2.058024447515475e-14 BR00117004 IGF1R final crispr E19 A549 144 599 Polylobed +0.1961023142509135 3.224983082657308e-14 BR00117004 CDK7 final crispr E12 A549 144 821 Polylobed +0.11219512195121951 6.716205959916286e-14 BR00117004 TUBB final crispr J17 A549 144 2460 Polylobed +0.18967932991143824 7.514752228940063e-14 BR00117001 TUBB4B final crispr C04 A549 144 847 Polylobed +0.28193583514826603 8.850327068868218e-14 BR00117004 SLC7A11 final crispr P05 A549 144 376 Polylobed +0.26146788990825687 1.6578443599256414e-13 BR00117004 CDK7 final crispr I14 A549 144 436 Polylobed +0.12166112326689935 1.890767953748113e-13 BR00117000 CACNA2D3 final crispr O07 A549 144 2018 Polylobed +0.13434650455927052 2.352116840664514e-13 BR00117001 RGS4 final crispr N11 A549 144 1645 Polylobed +0.20951631807414678 2.588696808691675e-13 BR00117004 FPR1 final crispr N22 A549 144 669 Polylobed +0.12552044513008961 2.9648993911977887e-13 BR00117001 SLC29A1 final crispr N21 A549 144 1860 Polylobed +0.11642890013805798 3.0348158715676497e-13 BR00117000 SLC29A1 final crispr N21 A549 144 2173 Polylobed +0.3633622154264356 3.351852377247894e-13 BR00117004 SIRT2 final crispr P01 A549 144 218 Polylobed +0.1817066760119152 3.3757584218668083e-13 BR00117004 PRKCE final crispr I17 A549 144 878 Polylobed +0.12532115362919594 3.7288588595249203e-13 BR00117004 AVPR1A final crispr J07 A549 144 1852 Polylobed +0.11074462154445697 4.3799839262448343e-13 BR00117003 IL1B final crispr H18 A549 144 2370 Polylobed +0.24695272607478175 5.678250002239439e-13 BR00117004 S1PR1 final crispr A18 A549 144 467 Polylobed +0.30629867155290885 9.043777514142547e-13 BR00117001 RPL3 final crispr K04 A549 144 296 Polylobed +0.18943298969072164 1.3865241316174546e-12 BR00117004 PDE4D final crispr J24 A549 144 776 Polylobed +0.10753255627593701 2.046368348022586e-12 BR00117004 EZH2 final crispr H09 A549 144 2374 Polylobed +0.20393645775259173 2.4009321432453707e-12 BR00117004 OPRL1 final crispr A04 A549 144 653 Polylobed +0.17611355108617602 3.2577233870608575e-12 BR00117004 BRAF final crispr F20 A549 144 869 Polylobed +0.21018062397372742 3.4624032912764864e-12 BR00117004 PTPN2 final crispr B12 A549 144 609 Polylobed +0.24770642201834864 3.754617758346621e-12 BR00117004 DYRK1B final crispr N16 A549 144 436 Polylobed +0.18850288122566655 4.932960956973635e-12 BR00117004 SCNN1G final crispr G24 A549 144 746 Polylobed +0.1895746887966805 7.505802182793351e-12 BR00117003 SLC29A1 final crispr E03 A549 144 723 Polylobed +0.27087631397976225 7.885153347542495e-12 BR00117004 KCNN1 final crispr D01 A549 144 351 Polylobed +0.12052156352164187 8.20489140726026e-12 BR00117004 AKR1B1 final crispr H17 A549 144 1791 Polylobed +0.1885245901639344 8.754052692898514e-12 BR00117004 COMT final crispr A12 A549 144 732 Polylobed +0.3073017810575376 1.0043418455013996e-11 BR00117001 RPL23A final crispr M18 A549 144 269 Polylobed +0.16150903741067676 1.2852881574826625e-11 BR00117004 ATM final crispr F14 A549 144 976 Polylobed +0.27853563205046344 1.5069374780841916e-11 BR00117004 CDK9 final crispr I20 A549 144 322 Polylobed +0.1160337552742616 1.5579017996045248e-11 BR00117000 AKR1B1 final crispr L21 A549 144 1896 Polylobed +0.18111254851228978 1.719484788102208e-11 BR00117000 IGF1R final crispr E19 A549 144 773 Polylobed +0.151268115942029 1.962355103419843e-11 BR00117000 AKT1 final crispr F06 A549 144 1104 Polylobed +0.22619067904916076 1.9707204730132656e-11 BR00117004 HIF1A final crispr M24 A549 144 485 Polylobed +0.1876750700280112 2.0986500195844764e-11 BR00117004 FFAR2 final crispr A24 A549 144 714 Polylobed +0.2241727615293914 2.4908038696984897e-11 BR00117004 OPRL1 final crispr A11 A549 144 491 Polylobed +0.09636787031996613 2.8284048405655145e-11 BR00117004 AGER final crispr J18 A549 144 2673 Polylobed +0.16880604234103508 3.066897475005746e-11 BR00117004 OPRM1 final crispr C23 A549 144 868 Polylobed +0.10488967178942529 3.133146352316399e-11 BR00117003 PDE3A final crispr O08 A549 144 2248 Polylobed +0.11411889596602973 4.2166434818110685e-11 BR00117003 BTK final crispr P17 A549 144 1884 Polylobed +0.21075467936349168 4.481676493449942e-11 BR00117001 SLC7A11 final crispr P05 A549 144 541 Polylobed +0.17319636884854275 4.8410020760334315e-11 BR00117004 FFAR2 final crispr A06 A549 144 805 Polylobed +0.12541634645493036 6.188263196852528e-11 BR00117003 LPAR1 final crispr B16 A549 144 1529 Polylobed +0.1139810027131214 9.464472461499748e-11 BR00117000 SCNN1G final crispr P15 A549 144 1821 Polylobed +0.17537878395949522 9.5246152576013e-11 BR00117004 AKR1C1 final crispr B13 A549 144 762 Polylobed +0.2751810895375252 1.069193785989298e-10 BR00117002 HDAC3 final crispr K19 A549 144 303 Polylobed +0.09436922299040584 1.226259551928942e-10 BR00117004 MAPK8 final crispr D13 A549 144 2632 Polylobed +0.2088168534543907 1.3397729650108286e-10 BR00117004 ADORA2A final crispr B22 A549 144 530 Polylobed +0.18059708321645906 1.3583024741681254e-10 BR00117004 FFAR4 final crispr G11 A549 144 707 Polylobed +0.1446156049057119 1.7959806943862544e-10 BR00117000 MMP2 final crispr D14 A549 144 1094 Polylobed +0.21236099230111205 1.9127433250559667e-10 BR00117004 KCNN4 final crispr K01 A549 144 504 Polylobed +0.16727716727716727 2.0301717099550961e-10 BR00117004 KCNMA1 final crispr A07 A549 144 819 Polylobed +0.21876126938333934 2.205161373612963e-10 BR00117004 SSTR2 final crispr P10 A549 144 470 Polylobed +0.1895380090268269 2.35281147167651e-10 BR00117004 KCNN1 final crispr B24 A549 144 626 Polylobed +0.2113426853707415 2.59818553714226e-10 BR00117004 DHH final crispr F05 A549 144 500 Polylobed +0.19929453262786595 2.908012967893005e-10 BR00117004 GABRB2 final crispr L22 A549 144 567 Polylobed +0.15071357372843938 3.012894745286751e-10 BR00117004 PNLIP final crispr C18 A549 144 989 Polylobed +0.1949461125518824 3.230998095548701e-10 BR00117005 MME final crispr G17 A549 144 583 Polylobed 0.32900101936799186 5.679639280082925e-11 BR00117004 SIRT2 final crispr P01 A549 144 218 Prometaphase 0.6507584165741769 8.123958706365356e-11 BR00117002 RPL23A final crispr M18 A549 144 51 Prometaphase 0.24215436810856658 1.1599130667705245e-10 BR00117000 AURKB final crispr C13 A549 144 396 Prometaphase @@ -889,6 +8809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.29600025680534153 2.7287410606059975e-07 BR00117004 AURKB final crispr C13 A549 144 176 Prometaphase 0.26656585718154735 4.3762627195975763e-07 BR00117003 AURKB final crispr C13 A549 144 212 Prometaphase 0.2 6.89885207988568e-07 BR00117003 PPAT final crispr E13 A549 144 370 Prometaphase +0.22126022126022127 7.880690311372862e-07 BR00117004 CA5A final crispr M01 A549 144 294 Prometaphase +0.11645750907493918 1.8652039438190474e-06 BR00117001 DDR2 final crispr A03 A549 144 1016 Prometaphase +0.3393553223388306 2.1982864357877332e-06 BR00117002 AURKB final crispr C13 A549 144 115 Prometaphase +0.12204480602270658 2.3344517251121852e-06 BR00117001 PTPN2 final crispr A15 A549 144 905 Prometaphase +0.16726896292113683 3.930312725466389e-06 BR00117005 CDK7 final crispr E12 A549 144 460 Prometaphase +0.17207119604278526 4.311232423807936e-06 BR00117001 CDK4 final crispr B15 A549 144 436 Prometaphase +0.15668437155414744 6.351471802111144e-06 BR00117003 CA5A final crispr M01 A549 144 508 Prometaphase +0.1333810888252149 6.506986026116028e-06 BR00117001 PPAT final crispr E13 A549 144 698 Prometaphase +0.11608423186581701 7.939004455286844e-06 BR00117001 FFAR2 final crispr A06 A549 144 911 Prometaphase +0.09453984486313514 8.058500713766973e-06 BR00117000 S1PR1 final crispr P23 A549 144 1373 Prometaphase +0.19838926174496643 1.1383249054344806e-05 BR00117002 HTR3A final crispr O20 A549 144 300 Prometaphase +0.2518885291690472 1.575379110507088e-05 BR00117003 SIRT2 final crispr P01 A549 144 178 Prometaphase +0.0711124391207256 1.7182108364788787e-05 BR00117001 CACNA2D3 final crispr O07 A549 144 2289 Prometaphase +0.10646766169154229 2.2213400939539675e-05 BR00117001 ABL1 final crispr C01 A549 144 1005 Prometaphase +0.16500671173114723 2.623651964129428e-05 BR00117004 CATSPER4 final crispr P02 A549 144 408 Prometaphase +0.16944393492585327 3.316183797145495e-05 BR00117001 RPL23A final crispr G14 A549 144 379 Prometaphase +0.18664640104223212 4.0534959685887957e-05 BR00117004 CDK4 final crispr P03 A549 144 302 Prometaphase +0.12432894674331323 4.671763015921666e-05 BR00117001 AURKB final crispr C13 A549 144 682 Prometaphase +0.24994388327721662 5.276422673462618e-05 BR00117003 TUBB3 final crispr K11 A549 144 162 Prometaphase +0.0996068322657918 5.9396520496956034e-05 BR00117005 DNMT3A final crispr L04 A549 144 1036 Prometaphase +0.11014449059176899 6.397132270500202e-05 BR00117001 OPRL1 final crispr A11 A549 144 841 Prometaphase +0.09364240505165293 6.402875131264514e-05 BR00117001 MAPK14 final crispr A20 A549 144 1165 Prometaphase +0.07677122856544895 6.436984116628992e-05 BR00117001 LPAR1 final crispr L01 A549 144 1739 Prometaphase +0.4106060606060606 7.245129053291121e-05 BR00117005 PLK1 final crispr G09 A549 144 55 Prometaphase +0.10345683152478083 7.714421506049557e-05 BR00117001 ADA final crispr O24 A549 144 941 Prometaphase +0.13755883962780516 8.544841254187502e-05 BR00117002 HSD11B1 final crispr O01 A549 144 522 Prometaphase +0.18832880208622316 0.00011119752197769654 BR00117001 RPL23A final crispr M18 A549 144 269 Prometaphase +0.1049043818211435 0.00011796653900464895 BR00117001 ICAM1 final crispr C20 A549 144 877 Prometaphase +0.13277710263035167 0.00012328841986028005 BR00117003 FPR1 final crispr N22 A549 144 541 Prometaphase +0.19072748956469887 0.00012516627882206723 BR00117002 PPAT final crispr E13 A549 144 258 Prometaphase +0.06665873663717278 0.00013289776201469365 BR00117003 KCNQ2 final crispr P13 A549 144 2141 Prometaphase +0.10392047934605769 0.00015744895454990922 BR00117001 ATP5F1D final crispr E15 A549 144 870 Prometaphase +0.1229495565675298 0.0001709527816336196 BR00117004 CACNG1 final crispr L02 A549 144 613 Prometaphase +0.14823529411764705 0.00017181685901400032 BR00117002 SLC7A11 final crispr P05 A549 144 425 Prometaphase +0.05373962523488901 0.000175242374696142 BR00117004 AKT1 final crispr J19 A549 144 3225 Prometaphase +0.18452620099867992 0.000202014909403307 BR00117002 SIRT2 final crispr P01 A549 144 266 Prometaphase +0.11553516580430183 0.0002166002154031879 BR00117001 SIRT2 final crispr P01 A549 144 679 Prometaphase +0.11749562899065909 0.00023169978083174676 BR00117001 GRIN2A final crispr A23 A549 144 643 Prometaphase +0.1576884944053633 0.00023735637499493095 BR00117003 CDK4 final crispr P03 A549 144 354 Prometaphase +0.1277578592017626 0.00024251398041089095 BR00117001 SLC7A11 final crispr P05 A549 144 541 Prometaphase +0.07626101389738955 0.00024367856544312637 BR00117000 ADA final crispr O06 A549 144 1534 Prometaphase +0.1668508509313026 0.00025308341244353985 BR00117004 GRIN2A final crispr A23 A549 144 314 Prometaphase +0.09422514898134403 0.0003071171151087978 BR00117001 KCNQ2 final crispr A16 A549 144 972 Prometaphase +0.1579819538434843 0.00032394033828135886 BR00117002 CA5A final crispr M01 A549 144 340 Prometaphase +0.150900269541779 0.00034770528154901665 BR00117002 ATP5F1D final crispr E15 A549 144 371 Prometaphase +0.09358730813943693 0.0003567652817992952 BR00117005 ADA final crispr O06 A549 144 973 Prometaphase +0.14285714285714285 0.0003717179593698629 BR00117004 HRH4 final crispr A08 A549 144 420 Prometaphase +0.3554778554778555 0.00038465672302230325 BR00117005 RPL23A final crispr M18 A549 144 65 Prometaphase +0.25384615384615383 0.00043379964060348276 BR00117005 RPL23A final crispr G14 A549 144 130 Prometaphase +0.06290057685348578 0.00045780758728016803 BR00117003 NTRK1 final crispr P07 A549 144 2094 Prometaphase +0.11459968602825746 0.00045993212779995847 BR00117001 AKR1C1 final crispr B06 A549 144 637 Prometaphase +0.10435931307793923 0.0005204607927656918 BR00117001 KCNN4 final crispr A22 A549 144 757 Prometaphase +0.08962608276716451 0.0005528050050907651 BR00117001 FLT3 final crispr G16 A549 144 1010 Prometaphase +0.11046290424857325 0.0005590330158639658 BR00117001 TGM2 final crispr B09 A549 144 665 Prometaphase +0.09064543486739067 0.0005591462943766161 BR00117001 PTGIS final crispr K17 A549 144 986 Prometaphase +0.09342998871644206 0.0005914143437919308 BR00117001 HIF1A final crispr M24 A549 144 918 Prometaphase +0.1341519226968723 0.0006140560198512199 BR00117002 S1PR1 final crispr A18 A549 144 439 Prometaphase +0.2296035655641567 0.0006994124174243495 BR00117002 CDK4 final crispr P03 A549 144 147 Prometaphase +0.07823014866119937 0.0007156905078948801 BR00117000 BAX final crispr L14 A549 144 1282 Prometaphase +0.13647058823529412 0.0007191010209597773 BR00117002 GHSR final crispr A09 A549 144 425 Prometaphase +0.14078691494179388 0.0007707204977872276 BR00117002 NAMPT final crispr I09 A549 144 387 Prometaphase +0.07976821742508286 0.0008237461158785804 BR00117001 OPRM1 final crispr C23 A549 144 1215 Prometaphase +0.14600550964187328 0.0008569666320118943 BR00117004 FOXM1 final crispr A19 A549 144 363 Prometaphase +0.08032447150743462 0.0008601284032054763 BR00117001 GHSR final crispr A09 A549 144 1185 Prometaphase +0.07201178686659579 0.0009459770543352893 BR00117004 HBB final crispr F21 A549 144 1464 Prometaphase +0.08544303503758435 0.0009499608429208336 BR00117001 CATSPER4 final crispr A02 A549 144 1039 Prometaphase +0.09119066670108149 0.000987330233191151 BR00117001 KRAS final crispr F07 A549 144 901 Prometaphase +0.06418754225168131 0.0009921874186313722 BR00117000 PTK2B final crispr N15 A549 144 1829 Prometaphase +0.07373508967759981 0.0010055132814453668 BR00117000 EZH2 final crispr H09 A549 144 1381 Prometaphase +0.08403837594223426 0.001064441791973246 BR00117004 ADRA2B final crispr H22 A549 144 1053 Prometaphase +0.07016393442622951 0.001093798424163502 BR00117001 GPR119 final crispr P21 A549 144 1525 Prometaphase +0.07859742069446025 0.0010963527785010667 BR00117000 AURKB final crispr M05 A549 144 1205 Prometaphase +0.27995169082125604 0.001138447299881235 BR00117005 RPL3 final crispr K04 A549 144 92 Prometaphase +0.08870116156282999 0.0011550592452753588 BR00117001 CSK final crispr B11 A549 144 947 Prometaphase +0.15716954155520707 0.0011728279659773562 BR00117000 PLK1 final crispr G09 A549 144 293 Prometaphase +0.10260115606936417 0.0013616185739717776 BR00117005 TUBB final crispr K13 A549 144 692 Prometaphase +0.08675078864353312 0.0014537744511099872 BR00117000 ATM final crispr G12 A549 144 951 Prometaphase +0.09785883132981636 0.0014542241978379184 BR00117001 HRH4 final crispr A08 A549 144 746 Prometaphase +0.12024048096192384 0.0014568330537088558 BR00117004 GRIN2A final crispr P09 A549 144 499 Prometaphase +0.13528733986486946 0.0015709668424374473 BR00117002 IMPDH1 final crispr G05 A549 144 379 Prometaphase +0.08108841964382688 0.0015744553538890602 BR00117001 OPRL1 final crispr A04 A549 144 1068 Prometaphase +0.05543091242047235 0.0016040422738098808 BR00117003 CHRM3 final crispr B17 A549 144 2300 Prometaphase +0.16163500678426052 0.0016188535562418086 BR00117004 RPL23A final crispr G14 A549 144 268 Prometaphase +0.1289562094531974 0.0016788515358251246 BR00117004 CTSG final crispr L12 A549 144 416 Prometaphase +0.09279129005625988 0.001734371721746074 BR00117002 P2RY12 final crispr O21 A549 144 809 Prometaphase +0.08434959349593496 0.0018132658247187986 BR00117003 ALDH2 final crispr A10 A549 144 984 Prometaphase +0.07448494453248812 0.001814137435668254 BR00117004 CA14 final crispr C19 A549 144 1262 Prometaphase +0.07610818698508412 0.0018877014125161886 BR00117001 S1PR4 final crispr H05 A549 144 1186 Prometaphase +0.13809918333530596 0.0019108885062574174 BR00117004 PPAT final crispr G13 A549 144 357 Prometaphase +0.08678848352963316 0.0019230283333829521 BR00117001 JAK1 final crispr M21 A549 144 908 Prometaphase 0.22157431058579113 1.5034838156355053e-53 BR00117005 LPAR1 final crispr L01 A549 144 2470 SmallIrregular 0.44562032539131774 6.481607450274479e-36 BR00117000 AURKB final crispr C13 A549 144 396 SmallIrregular 0.16279366501325662 5.611247368381642e-27 BR00117001 CACNA2D3 final crispr O07 A549 144 2289 SmallIrregular @@ -899,6 +8909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.13399497211613776 5.631877903599778e-20 BR00117005 PTK2B final crispr N15 A549 144 2494 SmallIrregular 0.13414634146341464 1.0505510254096706e-19 BR00117004 TUBB final crispr J17 A549 144 2460 SmallIrregular 0.16231682653741428 3.296619154541731e-19 BR00117001 PTK2B final crispr N15 A549 144 1629 SmallIrregular +0.11905727758130503 3.3065693575274487e-19 BR00117003 TUBB4B final crispr J13 A549 144 3036 SmallIrregular +0.1388721000511414 6.413615999716928e-19 BR00117005 ELANE final crispr N19 A549 144 2192 SmallIrregular +0.14915074309978768 1.0862964685974189e-18 BR00117003 BTK final crispr P17 A549 144 1884 SmallIrregular +0.15407669979746308 1.6628870372831811e-18 BR00117001 CACNG1 final crispr N23 A549 144 1738 SmallIrregular +0.1113949163050217 7.347334949256605e-18 BR00117004 AKT1 final crispr J19 A549 144 3225 SmallIrregular +0.23958166874694975 1.2206588265094978e-17 BR00117001 AURKB final crispr C13 A549 144 682 SmallIrregular +0.3599875472742367 1.6724157474490858e-17 BR00117000 PLK1 final crispr G09 A549 144 293 SmallIrregular +0.11447338059172006 1.988980339864068e-17 BR00117004 PORCN final crispr L13 A549 144 2968 SmallIrregular +0.31891891891891894 4.917742487506486e-17 BR00117003 PPAT final crispr E13 A549 144 370 SmallIrregular +0.12827861579414374 5.973301612973831e-17 BR00117003 CHRM3 final crispr B17 A549 144 2300 SmallIrregular +0.13345864661654136 6.23699849910725e-17 BR00117003 HCK final crispr H23 A549 144 2128 SmallIrregular +0.15544925261619574 1.4238434742867405e-16 BR00117003 LPAR1 final crispr B16 A549 144 1529 SmallIrregular +0.25588326466295547 1.9280270347553824e-16 BR00117003 FOXM1 final crispr A19 A549 144 557 SmallIrregular +0.3196602864748384 4.893439602545661e-16 BR00117001 PLK1 final crispr G09 A549 144 345 SmallIrregular +0.13673652158337812 1.3623085061248106e-15 BR00117001 SLC29A1 final crispr N21 A549 144 1860 SmallIrregular +0.4272919876733436 6.928038908271429e-15 BR00117004 AURKB final crispr C13 A549 144 176 SmallIrregular +0.1272523490862849 9.824623355219915e-15 BR00117000 CACNA2D3 final crispr O07 A549 144 2018 SmallIrregular +0.11930693772474445 1.385256253339942e-14 BR00117005 PDPK1 final crispr N18 A549 144 2282 SmallIrregular +0.12579265083260874 1.5418042392258095e-14 BR00117003 LYN final crispr N13 A549 144 2038 SmallIrregular +0.29594972067039105 1.8424277709757242e-14 BR00117000 RPL23A final crispr G14 A549 144 358 SmallIrregular +0.11190452295727778 4.316997825955391e-14 BR00117003 AKT1 final crispr J19 A549 144 2505 SmallIrregular +0.4265993265993266 5.590603184972857e-14 BR00117003 TUBB3 final crispr K11 A549 144 162 SmallIrregular +0.5584795321637427 7.349663571240357e-14 BR00117002 TUBB3 final crispr K11 A549 144 95 SmallIrregular +0.2423008475854372 9.984401117938159e-14 BR00117000 CDK4 final crispr B15 A549 144 516 SmallIrregular +0.12290284165003577 1.3324512228244764e-13 BR00117000 LYN final crispr N13 A549 144 1995 SmallIrregular +0.2648117650457947 2.1200334814945951e-13 BR00117003 CDK2 final crispr F08 A549 144 415 SmallIrregular +0.17557706872139353 2.17023962168241e-13 BR00117003 PPAT final crispr G13 A549 144 954 SmallIrregular +0.0978949858088931 4.675469099031672e-13 BR00117004 AKR1B1 final crispr L21 A549 144 3024 SmallIrregular +0.40784566838783703 4.784103555451205e-13 BR00117000 RPL23A final crispr M18 A549 144 166 SmallIrregular +0.23772102161100198 5.024581042749057e-13 BR00117000 TUBB3 final crispr K11 A549 144 509 SmallIrregular +0.12240103140686252 5.60714640855733e-13 BR00117000 LPAR1 final crispr L01 A549 144 1916 SmallIrregular +0.12217155099320649 1.5849148809052674e-12 BR00117004 AVPR1A final crispr J07 A549 144 1852 SmallIrregular +0.12096183139265466 1.9670040498956197e-12 BR00117005 LYN final crispr N13 A549 144 1874 SmallIrregular +0.10729332174138641 2.2323269093589293e-12 BR00117004 EZH2 final crispr H09 A549 144 2374 SmallIrregular +0.349030114671525 2.9252988279476284e-12 BR00117000 PLK1 final crispr F13 A549 144 217 SmallIrregular +0.12464843786292694 3.171487450571963e-12 BR00117003 CDK4 final crispr B15 A549 144 1738 SmallIrregular +0.19278800516643066 3.470661870761157e-12 BR00117000 PPAT final crispr E13 A549 144 716 SmallIrregular +0.1037892006636665 4.317403009657974e-12 BR00117004 RPL3 final crispr H11 A549 144 2481 SmallIrregular +0.10149942329873125 4.425122440428025e-12 BR00117004 F10 final crispr H15 A549 144 2601 SmallIrregular +0.22706035539215685 4.671138849902862e-12 BR00117000 FOXM1 final crispr A19 A549 144 512 SmallIrregular +0.10409781341561708 8.891889882427923e-12 BR00117004 KRAS final crispr D21 A549 144 2404 SmallIrregular +0.2128088595032964 1.0313120310615454e-11 BR00117005 GUCY1B1 final crispr H21 A549 144 562 SmallIrregular +0.12522796352583587 1.1790073841389985e-11 BR00117001 RGS4 final crispr N11 A549 144 1645 SmallIrregular +0.1186786718210536 1.2347761637696743e-11 BR00117000 SCNN1G final crispr P15 A549 144 1821 SmallIrregular +0.2017951500884072 1.3217959446574276e-11 BR00117003 HTR3A final crispr O20 A549 144 627 SmallIrregular +0.10814542107685228 1.7568440065691668e-11 BR00117000 SLC29A1 final crispr N21 A549 144 2173 SmallIrregular +0.37373833555513236 1.757897721011189e-11 BR00117003 SIRT2 final crispr P01 A549 144 178 SmallIrregular +0.12349397590361445 1.912203432256585e-11 BR00117004 JAK1 final crispr J09 A549 144 1660 SmallIrregular +0.1035903081908332 2.4803268064533633e-11 BR00117004 PTK2B final crispr N15 A549 144 2324 SmallIrregular +0.10164412482178752 3.0387663689966076e-11 BR00117004 CDK2 final crispr L19 A549 144 2403 SmallIrregular +0.10589197859766586 3.2210758151452036e-11 BR00117003 HSP90AB1 final crispr B04 A549 144 2198 SmallIrregular +0.45397301349325336 3.6209713814593605e-11 BR00117002 AURKB final crispr C13 A549 144 115 SmallIrregular +0.18682357756856324 3.8347924157726236e-11 BR00117001 PPAT final crispr E13 A549 144 698 SmallIrregular +0.10634867975921812 4.920188346135867e-11 BR00117003 KCNQ2 final crispr P13 A549 144 2141 SmallIrregular +0.4342479338842975 5.311648566054089e-11 BR00117003 RPL23A final crispr G14 A549 144 125 SmallIrregular +0.10117956646647883 7.209157420799521e-11 BR00117003 GAA final crispr L17 A549 144 2330 SmallIrregular +0.09420472978741569 1.1134698508558362e-10 BR00117003 CACNG1 final crispr N23 A549 144 2650 SmallIrregular +0.10610524536191256 2.0595919931587672e-10 BR00117003 CDK2 final crispr L19 A549 144 2027 SmallIrregular +0.24435087719298246 2.1383515910802194e-10 BR00117004 PPAT final crispr E13 A549 144 375 SmallIrregular +0.13165905631659056 2.421672541192122e-10 BR00117001 GJB4 final crispr N01 A549 144 1314 SmallIrregular +0.09193817751701983 2.599061304349474e-10 BR00117004 AGER final crispr J18 A549 144 2673 SmallIrregular +0.22811059907834103 2.6187679121585283e-10 BR00117004 CDK2 final crispr F08 A549 144 434 SmallIrregular +0.22008281573498964 2.6916745740613677e-10 BR00117005 CDK7 final crispr E12 A549 144 460 SmallIrregular +0.603030303030303 2.74093507068595e-10 BR00117005 PLK1 final crispr G09 A549 144 55 SmallIrregular +0.22689510844290364 2.7524834299396446e-10 BR00117001 CDK4 final crispr B15 A549 144 436 SmallIrregular +0.10343300066032184 2.881082318225933e-10 BR00117004 IGF1R final crispr M22 A549 144 2111 SmallIrregular +0.29039952295766247 3.269342493395495e-10 BR00117002 PPAT final crispr E13 A549 144 258 SmallIrregular +0.31668365613319743 4.224577147089681e-10 BR00117004 SIRT2 final crispr P01 A549 144 218 SmallIrregular +0.6167221605623382 7.713935016302137e-10 BR00117002 RPL23A final crispr M18 A549 144 51 SmallIrregular +0.11973644803833483 9.126285509671004e-10 BR00117001 TNF final crispr N17 A549 144 1485 SmallIrregular +0.10920766706507655 1.006792716109623e-09 BR00117004 KCNQ2 final crispr P13 A549 144 1782 SmallIrregular +0.10707647302589586 1.1918998157544509e-09 BR00117004 TUBB4B final crispr J13 A549 144 1841 SmallIrregular +0.10390543407578673 1.7808510735991612e-09 BR00117000 CACNG1 final crispr N23 A549 144 1912 SmallIrregular +0.10340732688311888 2.169581602369308e-09 BR00117000 NTRK1 final crispr P07 A549 144 1912 SmallIrregular +0.12178999359158137 2.2118949613227963e-09 BR00117001 UGT1A9 final crispr J01 A549 144 1376 SmallIrregular +0.11213235294117647 2.3615015750784397e-09 BR00117000 P2RY12 final crispr P19 A549 144 1632 SmallIrregular +0.26063354634783203 2.4421997617887213e-09 BR00117004 CA5A final crispr M01 A549 144 294 SmallIrregular +0.25734447942677235 2.474626693959613e-09 BR00117004 CDK4 final crispr P03 A549 144 302 SmallIrregular +0.08085169388408582 2.47911283707301e-09 BR00117004 S100B final crispr D22 A549 144 3123 SmallIrregular +0.1475180949933616 4.458939476782304e-09 BR00117002 COMT final crispr M02 A549 144 905 SmallIrregular +0.26919769183820674 5.121590724067855e-09 BR00117001 RPL23A final crispr M18 A549 144 269 SmallIrregular +0.1123823156783536 5.545298563764631e-09 BR00117001 TUBB4B final crispr J13 A549 144 1549 SmallIrregular +0.11344262295081967 5.783457412033029e-09 BR00117001 GPR119 final crispr P21 A549 144 1525 SmallIrregular +0.10426420645668331 5.973114090860817e-09 BR00117004 AKR1B1 final crispr H17 A549 144 1791 SmallIrregular +0.10126582278481013 6.994752933987342e-09 BR00117000 AKR1B1 final crispr L21 A549 144 1896 SmallIrregular +0.10597589800742165 7.432683343364119e-09 BR00117004 AKR1C1 final crispr B06 A549 144 1716 SmallIrregular +0.11038840097995674 9.31162959426162e-09 BR00117001 HCK final crispr H23 A549 144 1561 SmallIrregular +0.11032841920887462 1.1105952853089299e-08 BR00117001 LYN final crispr N13 A549 144 1550 SmallIrregular +0.0887965682789137 1.1521926484272546e-08 BR00117004 PLA2G1B final crispr J11 A549 144 2393 SmallIrregular +0.1124198234745902 1.4062428257263755e-08 BR00117000 UGT1A9 final crispr J01 A549 144 1479 SmallIrregular 0.12624584717607973 7.820568643964586e-06 BR00118046 SLC7A11 final crispr A05 U2OS 96 774 ADCCM 0.12656467315716272 1.9460667290697968e-05 BR00118046 TGFBR1 final crispr P24 U2OS 96 719 ADCCM 0.10517310539331233 3.4745515015784055e-05 BR00118047 TGM2 final crispr O03 U2OS 96 984 ADCCM @@ -909,6 +9009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.1399105190909553 0.0002914095075188532 BR00118046 KCNMA1 final crispr A07 U2OS 96 445 ADCCM 0.1220225486042461 0.00029165638059650874 BR00118047 PDE7A final crispr C10 U2OS 96 584 ADCCM 0.09528184264059321 0.00038971373428886113 BR00118047 EDNRB final crispr K06 U2OS 96 931 ADCCM +0.10755701957158267 0.0004299507622064757 BR00118046 HIF1A final crispr A01 U2OS 96 721 ADCCM +0.10751411673194018 0.00043392745783648554 BR00118047 CLK1 final crispr N05 U2OS 96 719 ADCCM +0.12056737588652482 0.0005431654143310795 BR00118045 FOXM1 final crispr A19 U2OS 96 564 ADCCM +0.10271263019935159 0.0005833005195037678 BR00118047 MMP2 final crispr E07 U2OS 96 760 ADCCM +0.08814098245803131 0.0007659098057518464 BR00118048 LPAR1 final crispr L01 U2OS 96 999 ADCCM +0.09393292590707578 0.0008339283561236059 BR00118046 ADA final crispr O06 U2OS 96 873 ADCCM +0.09426768164456462 0.0008737617360244205 BR00118045 SLC7A11 final crispr A05 U2OS 96 863 ADCCM +0.08644630529081133 0.000879626008154195 BR00118045 PPAT final crispr G13 U2OS 96 1023 ADCCM +0.09699780976220275 0.0009594860515524044 BR00118047 SSTR2 final crispr C02 U2OS 96 800 ADCCM +0.10215196413858593 0.0010913123880123498 BR00118045 SIRT2 final crispr P01 U2OS 96 709 ADCCM +0.1527846483634265 0.0011205331692852917 BR00118048 FOXM1 final crispr A19 U2OS 96 312 ADCCM +0.09199916891087369 0.0011302726261532203 BR00118047 CHRM2 final crispr O22 U2OS 96 866 ADCCM +0.10202587013425993 0.0011682337748825419 BR00118047 SIRT2 final crispr P01 U2OS 96 703 ADCCM +0.13755135911915314 0.001186197247111298 BR00118045 CCND1 final crispr B23 U2OS 96 383 ADCCM +0.10985700805690644 0.0012296608674205237 BR00118047 BRD4 final crispr M19 U2OS 96 598 ADCCM +0.08697799832325018 0.001430153178395154 BR00118047 RNASE1 final crispr K09 U2OS 96 939 ADCCM +0.10044895607779257 0.001469035973316825 BR00118047 ATP5F1D final crispr G21 U2OS 96 710 ADCCM +0.09242875138124834 0.0016732468483073588 BR00118047 PPARD final crispr N03 U2OS 96 819 ADCCM +0.0895056219882206 0.0018571129534240075 BR00118045 AKR1B1 final crispr L21 U2OS 96 858 ADCCM +0.09677437440430582 0.0019152800923435173 BR00118047 CCR1 final crispr O17 U2OS 96 733 ADCCM +0.1 0.0020024650342671314 BR00118047 HTR3A final crispr O20 U2OS 96 690 ADCCM +0.08430589663610118 0.0021299285696191194 BR00118046 HSD11B1 final crispr O23 U2OS 96 949 ADCCM +0.10453890105195707 0.0022358962118953357 BR00118047 PAK1 final crispr K10 U2OS 96 610 ADCCM +0.09280726867065853 0.0022884789050535027 BR00118047 CA14 final crispr C19 U2OS 96 772 ADCCM +0.10090361445783133 0.002302407861118841 BR00118047 GJB4 final crispr H01 U2OS 96 664 ADCCM +0.09089250003067222 0.002385331959344641 BR00118047 GABRB2 final crispr D10 U2OS 96 807 ADCCM +0.0797659593048642 0.002420544424333989 BR00118045 P2RY12 final crispr O21 U2OS 96 1045 ADCCM +0.10161194473332343 0.0024794174245332157 BR00118047 KDR final crispr O18 U2OS 96 636 ADCCM +0.08337326465146615 0.0024974922019041198 BR00118047 CACNA2D3 final crispr O07 U2OS 96 948 ADCCM +0.09562773861687941 0.0025146165408645345 BR00118047 CYP1A2 final crispr M15 U2OS 96 724 ADCCM +0.08466571572530568 0.0025168798454287327 BR00118047 CA5A final crispr I02 U2OS 96 921 ADCCM +0.08823529411764706 0.002660590419844941 BR00118047 KCNN4 final crispr K01 U2OS 96 850 ADCCM +0.11669997779258272 0.0029020268569649745 BR00118048 ALDH2 final crispr A10 U2OS 96 474 ADCCM +0.09590973201692525 0.0029259622413012132 BR00118047 CHEK2 final crispr M07 U2OS 96 709 ADCCM +0.09711103376261747 0.003025884832473062 BR00118045 ALDH2 final crispr A10 U2OS 96 676 ADCCM +0.09082754280970934 0.0030578193160817483 BR00118047 CYP2A6 final crispr O04 U2OS 96 774 ADCCM +0.10277324632952692 0.0030650008323780827 BR00118045 ANXA1 final crispr F24 U2OS 96 613 ADCCM +0.08465987206144686 0.0030764052755911037 BR00118045 CYP1A2 final crispr K22 U2OS 96 889 ADCCM +0.08302656030298106 0.003196807220327169 BR00118045 CDK9 final crispr M04 U2OS 96 921 ADCCM +0.12316478315464116 0.0036261996346490886 BR00118047 ANXA1 final crispr F24 U2OS 96 408 ADCCM +0.14674264669287812 0.003652855508501894 BR00118045 KCNN1 final crispr B24 U2OS 96 284 ADCCM +0.08236107870262342 0.003691288024114154 BR00118045 LYN final crispr F22 U2OS 96 916 ADCCM +0.11404436012106428 0.003712628045466128 BR00118045 HRH4 final crispr H24 U2OS 96 471 ADCCM +0.11266961620694765 0.003785806953214752 BR00118046 PDPK1 final crispr N18 U2OS 96 487 ADCCM +0.08738392472787651 0.003870115380136606 BR00118045 KCNH7 final crispr O16 U2OS 96 805 ADCCM +0.10718157975707315 0.004433146843030947 BR00118045 ADORA2A final crispr B22 U2OS 96 521 ADCCM +0.0838156971445317 0.00446017621206895 BR00118047 GPR119 final crispr G23 U2OS 96 863 ADCCM +0.09078590785907859 0.0045448720248294555 BR00118046 HSD11B1 final crispr O01 U2OS 96 738 ADCCM +0.09341831261437496 0.00455668256885705 BR00118046 SIRT2 final crispr P01 U2OS 96 689 ADCCM +0.08314350797266515 0.004608402055642597 BR00118045 KDR final crispr J02 U2OS 96 878 ADCCM +0.08769008312603223 0.0051409490907823275 BR00118048 CACNB4 final crispr I23 U2OS 96 766 ADCCM +0.10265486725663717 0.005164005008391986 BR00118047 DDR2 final crispr A03 U2OS 96 565 ADCCM +0.0826748315522939 0.005174612384164539 BR00118045 GHSR final crispr A09 U2OS 96 863 ADCCM +0.09100151086537225 0.005285629719548388 BR00118047 COMT final crispr M02 U2OS 96 704 ADCCM +0.08693231203824424 0.005310704005667854 BR00118047 PTGIR final crispr G08 U2OS 96 767 ADCCM +0.08702354186532758 0.006034727908293984 BR00118047 GLRA3 final crispr E21 U2OS 96 755 ADCCM +0.09816971713810316 0.006076258752117235 BR00118048 PTGIR final crispr G08 U2OS 96 601 ADCCM +0.07941793069429029 0.006281471573807932 BR00118045 IGF1R final crispr M22 U2OS 96 901 ADCCM +0.09065096557887198 0.006335457777636008 BR00118048 MME final crispr G17 U2OS 96 687 ADCCM +0.08356516484831011 0.0065359918540606535 BR00118045 CSF1R final crispr C08 U2OS 96 806 ADCCM +0.09797297297297297 0.006781267624302406 BR00118047 PDE7A final crispr C22 U2OS 96 592 ADCCM +0.08213698662535625 0.007167403979671957 BR00118048 SIRT2 final crispr P01 U2OS 96 824 ADCCM +0.09743589743589744 0.007713728984674536 BR00118046 PAK4 final crispr G22 U2OS 96 585 ADCCM +0.09861158840324637 0.00795557571602556 BR00118045 KCNN4 final crispr A22 U2OS 96 557 ADCCM +0.0914249776958741 0.008635614717260157 BR00118047 S1PR2 final crispr K02 U2OS 96 642 ADCCM +0.08788226630858528 0.009233403334459076 BR00118047 GAA final crispr L18 U2OS 96 679 ADCCM +0.09375814619049468 0.009262427146087805 BR00118046 OPRL1 final crispr A04 U2OS 96 602 ADCCM +0.08061276425572138 0.009406664696085313 BR00118045 HDAC6 final crispr K12 U2OS 96 812 ADCCM +0.0986364904449714 0.009517985283296277 BR00118046 FOXM1 final crispr A19 U2OS 96 536 ADCCM +0.10004825831359129 0.009535280946010326 BR00118046 ABL1 final crispr P20 U2OS 96 522 ADCCM +0.10285536323105167 0.009698276369948846 BR00118048 ANXA1 final crispr F24 U2OS 96 492 ADCCM +0.07372592572769199 0.010868228506934974 BR00118045 S1PR4 final crispr L05 U2OS 96 946 ADCCM +0.11354663385120238 0.011056152131871718 BR00118047 MAPK8 final crispr D13 U2OS 96 394 ADCCM +0.08812537757983618 0.01118303815678702 BR00118047 NTRK1 final crispr P07 U2OS 96 654 ADCCM +0.07615358865188873 0.011629243622400216 BR00118048 HTR3A final crispr O02 U2OS 96 877 ADCCM +0.07222319371852082 0.01224837450561729 BR00118045 CCR1 final crispr O17 U2OS 96 963 ADCCM +0.07820382849305266 0.01232605468418537 BR00118045 HTR3A final crispr O20 U2OS 96 820 ADCCM +0.09076175040518639 0.012371266363005918 BR00118046 BRD4 final crispr J16 U2OS 96 617 ADCCM +0.07971395981398614 0.012636824235263924 BR00118045 BRD4 final crispr M19 U2OS 96 786 ADCCM +0.09806654880094293 0.012859805327005818 BR00118045 RPL3 final crispr H11 U2OS 96 513 ADCCM +0.085383502170767 0.012946084771830603 BR00118047 FFAR4 final crispr E04 U2OS 96 691 ADCCM +0.08226511965682053 0.013145067917103615 BR00118045 KDR final crispr O18 U2OS 96 731 ADCCM +0.0924675764614789 0.01326128132021303 BR00118047 P3H1 final crispr N02 U2OS 96 576 ADCCM +0.07923135766557558 0.01378783967393239 BR00118047 P2RY12 final crispr O21 U2OS 96 782 ADCCM +0.10536818467236407 0.013977204968395756 BR00118046 AURKB final crispr C13 U2OS 96 434 ADCCM +0.09047932160348268 0.014132099717374991 BR00118046 OPRL1 final crispr A11 U2OS 96 596 ADCCM +0.11473375109738745 0.014134022509716125 BR00118045 BTK final crispr D24 U2OS 96 363 ADCCM +0.08972267536704731 0.014347157041251932 BR00118045 ITGB2 final crispr A17 U2OS 96 613 ADCCM +0.07900117211433443 0.014560240120841896 BR00118047 LPAR1 final crispr L01 U2OS 96 776 ADCCM +0.07685615237381377 0.014580710697222072 BR00118045 CYP2A6 final crispr O04 U2OS 96 821 ADCCM 0.22695035460992907 3.853083730267636e-13 BR00118045 FOXM1 final crispr A19 U2OS 96 564 Anaphase 0.22678571428571428 4.9492736129279e-13 BR00118047 AURKB final crispr C13 U2OS 96 560 Anaphase 0.2486776428518215 2.4840620164933083e-12 BR00118046 AURKB final crispr C13 U2OS 96 434 Anaphase @@ -919,6 +9109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.12653482105671623 4.5821682227417364e-08 BR00118047 GPR119 final crispr P21 U2OS 96 1094 Anaphase 0.2806379155435759 6.875644528378614e-08 BR00118047 RPL23A final crispr G14 U2OS 96 210 Anaphase 0.18511330912733193 7.142155237019689e-08 BR00118046 TUBB3 final crispr K11 U2OS 96 490 Anaphase +0.11306440704936946 7.519902558532902e-08 BR00118047 RGS4 final crispr N11 U2OS 96 1323 Anaphase +0.26908866995073893 7.899004639952853e-08 BR00118048 RPL23A final crispr M18 U2OS 96 231 Anaphase +0.22239449672084402 9.100431207791989e-08 BR00118045 RPL23A final crispr M18 U2OS 96 334 Anaphase +0.2018922305764411 1.1090340336917336e-07 BR00118047 FOXM1 final crispr A19 U2OS 96 399 Anaphase +0.2006281407035176 1.5671296399935028e-07 BR00118045 RPL23A final crispr G14 U2OS 96 400 Anaphase +0.14840113872358424 2.73729656772966e-07 BR00118045 SIRT2 final crispr P01 U2OS 96 709 Anaphase +0.2263036303630363 2.9536733185944154e-07 BR00118047 TUBB3 final crispr K11 U2OS 96 303 Anaphase +0.16643596059904356 3.2664227924663506e-07 BR00118045 KCNN4 final crispr A22 U2OS 96 557 Anaphase +0.311431989063568 4.6933562411303125e-07 BR00118046 RPL23A final crispr M18 U2OS 96 152 Anaphase +0.19397965879265092 8.900048410327027e-07 BR00118048 TUBB3 final crispr K11 U2OS 96 384 Anaphase +0.1620748150097979 1.8566178677231087e-06 BR00118046 ABL1 final crispr P20 U2OS 96 522 Anaphase +0.15801715720463105 2.3390701884638272e-06 BR00118046 FOXM1 final crispr A19 U2OS 96 536 Anaphase +0.11618669314796425 2.437217449020375e-06 BR00118047 SCNN1G final crispr P15 U2OS 96 1007 Anaphase +0.15135281610872556 2.8000343824092028e-06 BR00118046 PPAT final crispr E13 U2OS 96 578 Anaphase +0.32557471264367815 4.5903621050540155e-06 BR00118047 PLK1 final crispr F13 U2OS 96 116 Anaphase +0.20841547402647279 8.376665525956049e-06 BR00118046 RPL23A final crispr G14 U2OS 96 278 Anaphase +0.1974297139088136 8.4017456148427e-06 BR00118048 FOXM1 final crispr A19 U2OS 96 312 Anaphase +0.14192495921696574 8.411209990425972e-06 BR00118045 ITGB2 final crispr A17 U2OS 96 613 Anaphase +0.16055472737950038 8.607150871135406e-06 BR00118045 TUBB3 final crispr K11 U2OS 96 471 Anaphase +0.16981132075471697 9.369057852153702e-06 BR00118045 TUBB4B final crispr J13 U2OS 96 424 Anaphase +0.10942726268250035 1.5776316411984673e-05 BR00118046 CDK4 final crispr P03 U2OS 96 966 Anaphase +0.1563084428784388 1.6354599836324738e-05 BR00118045 HRH4 final crispr H24 U2OS 96 471 Anaphase +0.1478753392409998 2.2623063056079845e-05 BR00118046 ITGB2 final crispr A17 U2OS 96 516 Anaphase +0.1272126340535519 2.488446162882039e-05 BR00118045 PPAT final crispr E13 U2OS 96 687 Anaphase +0.1184375619097933 2.501757348667799e-05 BR00118045 CDK4 final crispr P03 U2OS 96 797 Anaphase +0.1020788648737832 3.174495913828047e-05 BR00118047 PTK2B final crispr N15 U2OS 96 1044 Anaphase +0.1390797458690786 3.639867835428113e-05 BR00118048 PPAT final crispr E13 U2OS 96 554 Anaphase +0.15527479790533327 3.751632793888169e-05 BR00118046 KCNMA1 final crispr A07 U2OS 96 445 Anaphase +0.13794049088166735 3.870128547160747e-05 BR00118046 DDR2 final crispr A03 U2OS 96 561 Anaphase +0.1385866036412747 4.092461709593924e-05 BR00118045 KCNMA1 final crispr A07 U2OS 96 554 Anaphase +0.17282865282865284 4.3519480925244616e-05 BR00118047 TUBB4B final crispr J13 U2OS 96 351 Anaphase +0.1266575184168713 5.237704035235749e-05 BR00118046 PIK3CG final crispr I08 U2OS 96 645 Anaphase +0.14042651389723226 5.7594975639968864e-05 BR00118045 ADORA2A final crispr B22 U2OS 96 521 Anaphase +0.12152829164816734 5.8127718579912154e-05 BR00118047 TGFBR1 final crispr P24 U2OS 96 696 Anaphase +0.16256131047557365 6.328711249974318e-05 BR00118045 CCND1 final crispr B23 U2OS 96 383 Anaphase +0.1188387932805512 7.358790835437547e-05 BR00118045 CACNB4 final crispr B01 U2OS 96 712 Anaphase +0.12370861237296867 7.846960163103111e-05 BR00118045 CDK2 final crispr F08 U2OS 96 655 Anaphase +0.12828252421870723 8.063217503104555e-05 BR00118045 SLCO2B1 final crispr I24 U2OS 96 605 Anaphase +0.17364277213219811 8.352523763641167e-05 BR00118047 BTK final crispr D24 U2OS 96 331 Anaphase +0.12925870032469017 9.119343383669651e-05 BR00118045 UGT1A9 final crispr J01 U2OS 96 591 Anaphase +0.1442284912434166 9.49743081785296e-05 BR00118046 ALDH2 final crispr A10 U2OS 96 468 Anaphase +0.1104403540609607 9.803410450613041e-05 BR00118045 KCNN1 final crispr D01 U2OS 96 804 Anaphase +0.12447781619129934 0.00010465423528731714 BR00118045 OPRL1 final crispr A11 U2OS 96 624 Anaphase +0.1388888888888889 0.0001172921071699888 BR00118047 DCK final crispr I07 U2OS 96 504 Anaphase +0.10529830842030466 0.00016030350861152606 BR00118045 GJB4 final crispr N01 U2OS 96 839 Anaphase +0.12073909990803279 0.0001647907767643483 BR00118045 CATSPER4 final crispr P02 U2OS 96 634 Anaphase +0.14648989350141273 0.00017569774349729096 BR00118047 PPAT final crispr E13 U2OS 96 430 Anaphase +0.12894465680571712 0.00018889114154182335 BR00118048 GAA final crispr L18 U2OS 96 547 Anaphase +0.1097501199340884 0.00019131731971598251 BR00118045 DYRK1B final crispr N16 U2OS 96 756 Anaphase +0.11189001456442758 0.0002500742956430478 BR00118045 PIK3CG final crispr E22 U2OS 96 708 Anaphase +0.09744405544779297 0.00027969914667390935 BR00118046 CYP2A6 final crispr C07 U2OS 96 920 Anaphase +0.16230376049653158 0.000282369343606218 BR00118046 TUBB4B final crispr J13 U2OS 96 330 Anaphase +0.11027122823239328 0.0002859682788566831 BR00118046 HIF1A final crispr A01 U2OS 96 721 Anaphase +0.22426575420587397 0.00031991734175920543 BR00118046 PLK1 final crispr F13 U2OS 96 168 Anaphase +0.11687261402451275 0.00032662348675203647 BR00118045 SLCO2B1 final crispr A21 U2OS 96 630 Anaphase +0.08828828828828829 0.00034690165749359087 BR00118047 KCNQ2 final crispr P13 U2OS 96 1110 Anaphase +0.12302335147752384 0.0003714888116244025 BR00118046 CDK2 final crispr L19 U2OS 96 561 Anaphase +0.10151413074677386 0.00037527486995673413 BR00118045 CYP2A6 final crispr O04 U2OS 96 821 Anaphase +0.11757290483146675 0.0003947639862539547 BR00118047 BRD4 final crispr J16 U2OS 96 606 Anaphase +0.17197361244578344 0.0004087837197925416 BR00118048 RPL23A final crispr G14 U2OS 96 278 Anaphase +0.12826217299378334 0.0004220028749222281 BR00118047 ERBB2 final crispr I11 U2OS 96 503 Anaphase +0.11366362879975232 0.0004320409116902269 BR00118048 CDK4 final crispr P03 U2OS 96 642 Anaphase +0.13228886168910647 0.0004442368216551825 BR00118046 DCK final crispr I07 U2OS 96 473 Anaphase +0.11222760657403717 0.00046370656826218035 BR00118048 DCK final crispr I07 U2OS 96 657 Anaphase +0.10443864229765012 0.0004658167008536283 BR00118046 CDC25A final crispr D06 U2OS 96 766 Anaphase +0.10093141431399834 0.00047851437986365993 BR00118045 PDE3A final crispr P18 U2OS 96 809 Anaphase +0.1174950117903138 0.00048411560934933447 BR00118046 OPRL1 final crispr A11 U2OS 96 596 Anaphase +0.19194828469022018 0.0005319613280623649 BR00118045 JAK1 final crispr J09 U2OS 96 217 Anaphase +0.10150375939849623 0.0005326436078195405 BR00118045 NTRK1 final crispr P07 U2OS 96 798 Anaphase +0.13020615866388308 0.000532822958749187 BR00118047 CDK9 final crispr I20 U2OS 96 480 Anaphase +0.09891585760517799 0.0005524339685782871 BR00118045 CA5A final crispr M01 U2OS 96 825 Anaphase +0.11794871794871795 0.0005772185288364449 BR00118046 HSP90AB1 final crispr B04 U2OS 96 585 Anaphase +0.14662634496964916 0.0005801749747178833 BR00118046 CSF1R final crispr J15 U2OS 96 371 Anaphase +0.10652328969160653 0.0006033447517703253 BR00118047 HSP90AB1 final crispr B04 U2OS 96 702 Anaphase +0.10762545013966951 0.0006081242653672361 BR00118045 S1PR1 final crispr A18 U2OS 96 688 Anaphase +0.12324090638044126 0.0006714401146981948 BR00118047 S1PR1 final crispr A18 U2OS 96 520 Anaphase +0.10374643009737121 0.000688358634548178 BR00118045 PDE4D final crispr J24 U2OS 96 732 Anaphase +0.12233947215127482 0.0007618813398975888 BR00118047 RET final crispr D17 U2OS 96 519 Anaphase +0.10289004107720225 0.0007808252334053695 BR00118045 KDR final crispr O18 U2OS 96 731 Anaphase +0.12173661231399804 0.00080448092453644 BR00118048 CYP3A4 final crispr D04 U2OS 96 522 Anaphase +0.09281767955801105 0.0008165299746012534 BR00118045 DDR2 final crispr B03 U2OS 96 905 Anaphase +0.11867049288031509 0.0008346436574583303 BR00118046 GPR119 final crispr P21 U2OS 96 543 Anaphase +0.10522075682042868 0.0008488566484057509 BR00118046 SIRT2 final crispr P01 U2OS 96 689 Anaphase +0.12233605771075554 0.0008673552567737799 BR00118046 PARP3 final crispr L11 U2OS 96 511 Anaphase +0.09242761692650334 0.000925647476247298 BR00118045 SCNN1G final crispr G24 U2OS 96 898 Anaphase +0.20525451559934318 0.000935752461619377 BR00118046 PLK1 final crispr G09 U2OS 96 175 Anaphase +0.10754334831793706 0.0009362142549739169 BR00118045 VEGFA final crispr H02 U2OS 96 653 Anaphase +0.1001949648215648 0.0009808426747996589 BR00118045 HSP90AB1 final crispr B04 U2OS 96 752 Anaphase +0.0975 0.0009886460460131023 BR00118045 GPR119 final crispr G23 U2OS 96 800 Anaphase +0.126610610647567 0.001003626480516074 BR00118047 CDC25A final crispr D06 U2OS 96 467 Anaphase 0.13028603254167165 2.7765833313788283e-10 BR00118047 RGS4 final crispr N11 U2OS 96 1323 Apoptosis 0.18085106382978725 1.7891494392571686e-08 BR00118045 FOXM1 final crispr A19 U2OS 96 564 Apoptosis 0.1425709883337002 2.7221860810233864e-07 BR00118045 KCNJ1 final crispr F03 U2OS 96 770 Apoptosis @@ -929,6 +9209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.11396773974440004 9.371885542859167e-06 BR00118047 EDNRB final crispr K06 U2OS 96 931 Apoptosis 0.10705017718516885 1.1425697784347027e-05 BR00118045 P2RY12 final crispr O21 U2OS 96 1045 Apoptosis 0.10320634663751406 1.4386787194291847e-05 BR00118045 CYP2A6 final crispr C07 U2OS 96 1102 Apoptosis +0.11335704249090076 1.942199272057408e-05 BR00118045 CYP1A2 final crispr K22 U2OS 96 889 Apoptosis +0.1016302003476508 2.5046087958678383e-05 BR00118045 GLRA3 final crispr E21 U2OS 96 1079 Apoptosis +0.1335891812865497 3.21499345999337e-05 BR00118047 GRIN2A final crispr P09 U2OS 96 608 Apoptosis +0.15921713512991403 5.723319332887799e-05 BR00118047 ANXA1 final crispr F24 U2OS 96 408 Apoptosis +0.09489071912740087 6.967183043833961e-05 BR00118045 CCR1 final crispr G02 U2OS 96 1124 Apoptosis +0.10356347438752785 0.00012971674862362768 BR00118045 GABRB2 final crispr D10 U2OS 96 898 Apoptosis +0.18821476205340673 0.0001328563561656904 BR00118047 RPL23A final crispr M18 U2OS 96 262 Apoptosis +0.1339870478088233 0.00014539058446891303 BR00118045 ADORA2A final crispr B22 U2OS 96 521 Apoptosis +0.11104502386057127 0.00015427486427958156 BR00118046 KCNJ1 final crispr E14 U2OS 96 760 Apoptosis +0.19933945364979846 0.00016838957771684175 BR00118048 RPL23A final crispr M18 U2OS 96 231 Apoptosis +0.1086814993791738 0.00019487961717149058 BR00118046 SLC7A11 final crispr A05 U2OS 96 774 Apoptosis +0.16666666666666666 0.00020298764839854144 BR00118047 KCNN4 final crispr A22 U2OS 96 330 Apoptosis +0.10494254975285777 0.00021367428047733208 BR00118045 ADH1C final crispr D02 U2OS 96 824 Apoptosis +0.0970117418412652 0.0002317048252786713 BR00118045 PAK1 final crispr N06 U2OS 96 949 Apoptosis +0.12798760872155368 0.00024242671999912937 BR00118048 F10 final crispr H15 U2OS 96 539 Apoptosis +0.12071778140293637 0.00026009675677878154 BR00118045 ITGB2 final crispr A17 U2OS 96 613 Apoptosis +0.1075174748703054 0.0002782694970699691 BR00118047 GLRA3 final crispr E21 U2OS 96 755 Apoptosis +0.12524609539347964 0.00028097172563748085 BR00118045 KCNN4 final crispr A22 U2OS 96 557 Apoptosis +0.12930303296189055 0.0002821278796238574 BR00118046 ABL1 final crispr P20 U2OS 96 522 Apoptosis +0.0999720167794713 0.0002877437556073045 BR00118048 HTR3A final crispr O02 U2OS 96 877 Apoptosis +0.10022779043280182 0.00029260736986805866 BR00118045 KDR final crispr J02 U2OS 96 878 Apoptosis +0.14665413533834587 0.0002992522830458585 BR00118047 FOXM1 final crispr A19 U2OS 96 399 Apoptosis +0.1299290845073109 0.000306467238836943 BR00118048 KCNQ2 final crispr A16 U2OS 96 513 Apoptosis +0.12665295020225972 0.0003082761817206185 BR00118046 FOXM1 final crispr A19 U2OS 96 536 Apoptosis +0.15998360422013116 0.00032172638187355295 BR00118045 RPL23A final crispr M18 U2OS 96 334 Apoptosis +0.10002387236599287 0.00033377317893626364 BR00118045 SLC7A11 final crispr A05 U2OS 96 863 Apoptosis +0.12396436641300677 0.00035469939430834275 BR00118045 KCNMA1 final crispr A07 U2OS 96 554 Apoptosis +0.11159420289855072 0.000366589509709594 BR00118047 PTPN2 final crispr A15 U2OS 96 690 Apoptosis +0.08748663101604279 0.0003948575921436417 BR00118045 BAX final crispr E06 U2OS 96 1105 Apoptosis +0.12212389380530973 0.00043205201656327743 BR00118047 DDR2 final crispr A03 U2OS 96 565 Apoptosis +0.13586890057478293 0.0004720404051873246 BR00118047 SLCO2B1 final crispr A21 U2OS 96 442 Apoptosis +0.1273767374770522 0.0005766643321066465 BR00118048 ANXA1 final crispr F24 U2OS 96 492 Apoptosis +0.08506705283410526 0.0006260998030374476 BR00118046 CACNG1 final crispr L02 U2OS 96 1103 Apoptosis +0.12632611326739285 0.000675538037429031 BR00118046 TUBB3 final crispr K11 U2OS 96 490 Apoptosis +0.11033551982353283 0.0007147359669226264 BR00118048 CDK4 final crispr P03 U2OS 96 642 Apoptosis +0.09755799391734749 0.0007518948574884588 BR00118045 HTR3A final crispr O20 U2OS 96 820 Apoptosis +0.17374517374517376 0.0007849432561145569 BR00118045 FFAR2 final crispr A24 U2OS 96 259 Apoptosis +0.09985444153624272 0.0008025912000338318 BR00118046 ATP5F1D final crispr E15 U2OS 96 776 Apoptosis +0.10897126783202733 0.001013361149358516 BR00118045 SLCO2B1 final crispr A21 U2OS 96 630 Apoptosis +0.10323245029845592 0.0010613997376399157 BR00118047 TGFBR1 final crispr P24 U2OS 96 696 Apoptosis +0.10090152565880721 0.0011117628596737919 BR00118046 HIF1A final crispr A01 U2OS 96 721 Apoptosis +0.11424318276633671 0.0011514117570646 BR00118045 SCNN1G final crispr P15 U2OS 96 561 Apoptosis +0.13258958050950545 0.0011700589566423223 BR00118048 FFAR2 final crispr A06 U2OS 96 414 Apoptosis +0.13366834170854272 0.0013596517128483393 BR00118045 RPL23A final crispr G14 U2OS 96 400 Apoptosis +0.08365026270772238 0.0013749201489397125 BR00118045 PPAT final crispr G13 U2OS 96 1023 Apoptosis +0.09756782170575275 0.0013860471370583808 BR00118046 KCNMA1 final crispr E23 U2OS 96 754 Apoptosis +0.11765903538141345 0.0014309646532142835 BR00118047 KCNMA1 final crispr A07 U2OS 96 516 Apoptosis +0.1797020683742364 0.0015874378999660766 BR00118047 KCNN1 final crispr B24 U2OS 96 217 Apoptosis +0.09585109744662995 0.0016652699336775765 BR00118045 KCNJ1 final crispr E14 U2OS 96 759 Apoptosis +0.0866410565108307 0.0016820899076836111 BR00118048 PORCN final crispr N07 U2OS 96 934 Apoptosis +0.21086807928913193 0.0016995575915897268 BR00118046 RPL23A final crispr M18 U2OS 96 152 Apoptosis +0.09732900318133617 0.0017065445082424652 BR00118046 ADH1C final crispr P04 U2OS 96 736 Apoptosis +0.09840057855664501 0.0018379721161973887 BR00118047 OPRL1 final crispr A11 U2OS 96 707 Apoptosis +0.11444652908067542 0.0018421471921950957 BR00118047 KCNQ2 final crispr A16 U2OS 96 533 Apoptosis +0.13566883748783592 0.0019931266099053103 BR00118047 HRH4 final crispr A08 U2OS 96 365 Apoptosis +0.1361138861138861 0.0020946797182793994 BR00118045 BTK final crispr D24 U2OS 96 363 Apoptosis +0.08022083771951621 0.0021145995261702345 BR00118045 S1PR2 final crispr K02 U2OS 96 1055 Apoptosis +0.11835388715724805 0.002285713014475146 BR00118045 HRH4 final crispr H24 U2OS 96 471 Apoptosis +0.10626086802490531 0.0025424960286809213 BR00118047 FPR1 final crispr I18 U2OS 96 583 Apoptosis +0.09887225571101274 0.002694515064946864 BR00118048 PPARD final crispr N03 U2OS 96 671 Apoptosis +0.09700427960057062 0.002715435227825536 BR00118045 CACNA2D3 final crispr N24 U2OS 96 701 Apoptosis +0.08747091208354617 0.00303592674594119 BR00118046 CHRM2 final crispr O22 U2OS 96 839 Apoptosis +0.11123577678045242 0.0030646011981538494 BR00118045 RPL3 final crispr H11 U2OS 96 513 Apoptosis +0.08590863194981524 0.003109591296566187 BR00118046 LPAR1 final crispr L01 U2OS 96 864 Apoptosis +0.08596685501197271 0.003198359085130148 BR00118048 TGM2 final crispr O03 U2OS 96 859 Apoptosis +0.1375263206078916 0.0034367235172140316 BR00118047 BTK final crispr D24 U2OS 96 331 Apoptosis +0.09106137570731848 0.003658024085279293 BR00118048 SLC7A11 final crispr P05 U2OS 96 743 Apoptosis +0.08305089385252429 0.0038461859513626243 BR00118045 FPR1 final crispr N22 U2OS 96 897 Apoptosis +0.10162540564286422 0.00385693130597089 BR00118045 KCNQ2 final crispr P13 U2OS 96 595 Apoptosis +0.08500446948103423 0.00396340745640314 BR00118047 PRKCE final crispr K05 U2OS 96 843 Apoptosis +0.07443492205018332 0.0041466773004940815 BR00118045 HTR2C final crispr L03 U2OS 96 1097 Apoptosis +0.09167285228737743 0.004335967656027976 BR00118046 PTGIR final crispr G10 U2OS 96 716 Apoptosis +0.10154432669940554 0.004594257336010702 BR00118046 FFAR2 final crispr A06 U2OS 96 583 Apoptosis +0.07786951343572439 0.0046490283327801545 BR00118047 TGM2 final crispr O03 U2OS 96 984 Apoptosis +0.07904404424390049 0.004894516009832591 BR00118047 CACNA2D3 final crispr O07 U2OS 96 948 Apoptosis +0.08081144407448514 0.004957959017800311 BR00118047 CCR1 final crispr G02 U2OS 96 900 Apoptosis +0.16599281221922732 0.005025958664772218 BR00118047 RPL23A final crispr G14 U2OS 96 210 Apoptosis +0.08278303289904218 0.005074338064627021 BR00118045 AKR1B1 final crispr L21 U2OS 96 858 Apoptosis +0.09026997803548237 0.0057315779959395945 BR00118045 IL1B final crispr H06 U2OS 96 709 Apoptosis +0.07729451981166556 0.005741840462574782 BR00118046 PNLIP final crispr C06 U2OS 96 965 Apoptosis +0.15399789137162875 0.005796722589597484 BR00118045 AVPR1A final crispr J07 U2OS 96 242 Apoptosis +0.1097890409721281 0.005869985032776642 BR00118045 TUBB3 final crispr K11 U2OS 96 471 Apoptosis +0.10065401994266564 0.006139297486625274 BR00118046 DDR2 final crispr A03 U2OS 96 561 Apoptosis +0.07948826196288615 0.006147270421671711 BR00118046 ICAM1 final crispr C20 U2OS 96 903 Apoptosis +0.08720276744109912 0.006268468810730603 BR00118048 PAK4 final crispr G22 U2OS 96 741 Apoptosis +0.0793538044148477 0.0064385691273910264 BR00118045 IGF1R final crispr M22 U2OS 96 901 Apoptosis +0.08627450980392157 0.006708891691455654 BR00118045 ATM final crispr F14 U2OS 96 765 Apoptosis +0.09060356964439802 0.006911665421218525 BR00118045 HRH4 final crispr A08 U2OS 96 679 Apoptosis +0.07330571752328208 0.006989327396934663 BR00118045 CACNG1 final crispr L02 U2OS 96 1033 Apoptosis +0.11707317073170732 0.0072093383569935155 BR00118047 PDPK1 final crispr N18 U2OS 96 410 Apoptosis 0.14971507049664237 3.930532584284039e-06 BR00118046 S1PR1 final crispr P23 U2OS 96 579 Binuclear 0.20430107526881722 1.6484078288943752e-05 BR00118045 PLK1 final crispr G09 U2OS 96 279 Binuclear 0.09222659824163583 2.2761661816871364e-05 BR00118047 RGS4 final crispr N11 U2OS 96 1323 Binuclear @@ -939,6 +9309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.22686371100164204 0.00017690767216403276 BR00118046 PLK1 final crispr G09 U2OS 96 175 Binuclear 0.09570587536689232 0.00018805280022088063 BR00118048 LPAR1 final crispr L01 U2OS 96 999 Binuclear 0.10652229126805399 0.00029024618109374446 BR00118045 KCNJ1 final crispr F03 U2OS 96 770 Binuclear +0.10829430305172617 0.00032087257982521035 BR00118046 ADH1C final crispr P04 U2OS 96 736 Binuclear +0.12573385169597318 0.0003885712783758136 BR00118046 AVPR1A final crispr J07 U2OS 96 529 Binuclear +0.1196836607513799 0.0004372817236624998 BR00118047 FGF1 final crispr I19 U2OS 96 581 Binuclear +0.13848076505107584 0.0004509268386734485 BR00118047 TNNC1 final crispr D09 U2OS 96 430 Binuclear +0.18685689034783157 0.0008351853669432628 BR00118046 KCNN1 final crispr B24 U2OS 96 217 Binuclear +0.10292072322670376 0.0009768598167524708 BR00118046 TGFBR1 final crispr P24 U2OS 96 719 Binuclear +0.11038792403830547 0.0010805575113477489 BR00118047 BRD4 final crispr J16 U2OS 96 606 Binuclear +0.08265579029589995 0.001081877869062599 BR00118047 GPR119 final crispr P21 U2OS 96 1094 Binuclear +0.11347517730496454 0.0013899957091882665 BR00118045 FOXM1 final crispr A19 U2OS 96 564 Binuclear +0.07692477357632235 0.001428339010311798 BR00118045 PTGIR final crispr G08 U2OS 96 1204 Binuclear +0.09070532859889818 0.0019840888583482342 BR00118045 ADH1C final crispr D02 U2OS 96 824 Binuclear +0.11450381679389313 0.0020589087585979483 BR00118046 TNF final crispr N17 U2OS 96 524 Binuclear +0.18133663366336633 0.0021895726159967947 BR00118048 PLK1 final crispr G09 U2OS 96 200 Binuclear +0.09922907488986785 0.0022029551228916256 BR00118047 JAK1 final crispr M21 U2OS 96 680 Binuclear +0.12602523863034576 0.0032628554972953055 BR00118046 RPL3 final crispr K04 U2OS 96 393 Binuclear +0.07741513384523248 0.0036083090083987002 BR00118045 EZH2 final crispr C05 U2OS 96 1043 Binuclear +0.1050656660412758 0.005539470251899473 BR00118047 KCNQ2 final crispr A16 U2OS 96 533 Binuclear +0.08998211343182683 0.006062183345007326 BR00118047 SIRT2 final crispr P01 U2OS 96 703 Binuclear +0.07930339227737608 0.006236493454978537 BR00118048 PRKCB final crispr N04 U2OS 96 907 Binuclear +0.10885807247008222 0.0072923965572342245 BR00118048 AURKB final crispr C13 U2OS 96 466 Binuclear +0.08496484358553325 0.00782588299888855 BR00118046 HBB final crispr F21 U2OS 96 754 Binuclear +0.085219707057257 0.008532335437671141 BR00118045 TGM2 final crispr B09 U2OS 96 751 Binuclear +0.12573099415204678 0.008918197454094121 BR00118047 AKR1B1 final crispr H17 U2OS 96 342 Binuclear +0.09884767918843934 0.009089478609559892 BR00118048 F10 final crispr H15 U2OS 96 539 Binuclear +0.09865221572733288 0.009551673562277617 BR00118046 KCNK1 final crispr N20 U2OS 96 542 Binuclear +0.08885542168674698 0.010543118919041201 BR00118047 DNMT3A final crispr L06 U2OS 96 664 Binuclear +0.11345238095238096 0.01093567790074118 BR00118047 FOXM1 final crispr A19 U2OS 96 399 Binuclear +0.09306010198208045 0.011097403753437863 BR00118046 ANXA1 final crispr F24 U2OS 96 586 Binuclear +0.07692952532385793 0.011336698642977079 BR00118048 TGM2 final crispr O03 U2OS 96 859 Binuclear +0.08522026540377879 0.011578112464549747 BR00118047 TGFBR1 final crispr P24 U2OS 96 696 Binuclear +0.07149950347567031 0.011601154351135656 BR00118047 SCNN1G final crispr P15 U2OS 96 1007 Binuclear +0.0850772605089134 0.012306893699705742 BR00118048 HCK final crispr M23 U2OS 96 697 Binuclear +0.09241342849590273 0.012510737893195305 BR00118048 GHSR final crispr A09 U2OS 96 585 Binuclear +0.10743744207599629 0.014267258510461659 BR00118046 MAPK14 final crispr A20 U2OS 96 415 Binuclear +0.09608066617908576 0.015096507219163929 BR00118047 CDK2 final crispr L19 U2OS 96 521 Binuclear +0.0656900349930055 0.015983667594009092 BR00118046 CACNG1 final crispr L02 U2OS 96 1103 Binuclear +0.11947267234276297 0.01598486198622962 BR00118047 BTK final crispr D24 U2OS 96 331 Binuclear +0.07830778270391539 0.016072830782342652 BR00118046 CA14 final crispr G15 U2OS 96 776 Binuclear +0.08867687756999922 0.016685945904329067 BR00118048 HIF1A final crispr M24 U2OS 96 599 Binuclear +0.09722222222222222 0.017017207723285535 BR00118047 DCK final crispr I07 U2OS 96 504 Binuclear +0.08712474311984915 0.017291796278587204 BR00118047 CACNG1 final crispr L02 U2OS 96 613 Binuclear +0.08201438848920864 0.01861931664580188 BR00118046 TBXAS1 final crispr E24 U2OS 96 695 Binuclear +0.07720148848326815 0.01971082135840929 BR00118047 PTGIR final crispr G08 U2OS 96 767 Binuclear +0.08762162488257651 0.019870482202074418 BR00118048 HTR3A final crispr O20 U2OS 96 591 Binuclear +0.07398473010308666 0.020168396222512677 BR00118046 RPL3 final crispr H11 U2OS 96 820 Binuclear +0.08194966479832949 0.02056011559484636 BR00118048 FPR1 final crispr N22 U2OS 96 675 Binuclear +0.08589951377633712 0.02103763049735279 BR00118046 BRD4 final crispr J16 U2OS 96 617 Binuclear +0.0706401766004415 0.021729326071461174 BR00118046 P2RY12 final crispr O21 U2OS 96 906 Binuclear +0.0734071281516537 0.022302925285827772 BR00118045 FGF1 final crispr J12 U2OS 96 822 Binuclear +0.07896254062238785 0.022440292464045018 BR00118045 IL1B final crispr H06 U2OS 96 709 Binuclear +0.06469623518674973 0.022967105201187256 BR00118045 S1PR2 final crispr K02 U2OS 96 1055 Binuclear +0.08162138332675932 0.02327577194848815 BR00118047 S1PR1 final crispr P23 U2OS 96 658 Binuclear +0.105 0.02424717195471133 BR00118047 GUCY1B1 final crispr H21 U2OS 96 400 Binuclear +0.06442189591009918 0.02522892166629346 BR00118047 PTK2B final crispr N15 U2OS 96 1044 Binuclear +0.0857223555994916 0.025348218640752845 BR00118047 PDE7A final crispr C10 U2OS 96 584 Binuclear +0.0752249028111097 0.02599391218072937 BR00118046 KCNMA1 final crispr E23 U2OS 96 754 Binuclear +0.06479425566625203 0.02635686151999626 BR00118048 AURKB final crispr M05 U2OS 96 1018 Binuclear +0.08573280084394544 0.026548929334520643 BR00118046 CSK final crispr B11 U2OS 96 575 Binuclear +0.07972677121088162 0.02664552815327611 BR00118047 CDK2 final crispr F08 U2OS 96 662 Binuclear +0.08913438800520387 0.02771026072119779 BR00118045 AURKB final crispr C13 U2OS 96 526 Binuclear +0.07518186824334117 0.027932987289592228 BR00118048 KCNH7 final crispr O16 U2OS 96 742 Binuclear +0.061730233084257666 0.028128969972260935 BR00118045 HTR2C final crispr L03 U2OS 96 1097 Binuclear +0.08386978005440929 0.030058519177175003 BR00118047 NAMPT final crispr I09 U2OS 96 587 Binuclear +0.0656042396749296 0.0302899457510463 BR00118046 PNLIP final crispr C06 U2OS 96 965 Binuclear +0.0752673340919453 0.03165760005755502 BR00118046 CACNB4 final crispr B01 U2OS 96 722 Binuclear +0.06616794627818973 0.031721851015225414 BR00118047 EDNRB final crispr K06 U2OS 96 931 Binuclear +0.08822889958466405 0.032404952919580905 BR00118046 CACNA2D3 final crispr N24 U2OS 96 516 Binuclear +0.09062926491275956 0.033289953744121206 BR00118048 FGF1 final crispr J12 U2OS 96 485 Binuclear +0.07498923822503119 0.034156108430530165 BR00118046 CLK1 final crispr N05 U2OS 96 711 Binuclear +0.08298114386424053 0.034362575734986134 BR00118048 LYN final crispr N13 U2OS 96 583 Binuclear +0.08780719053398059 0.03495711179917003 BR00118047 GAA final crispr L17 U2OS 96 515 Binuclear +0.07848145353224589 0.035237740163760356 BR00118048 CDK4 final crispr P03 U2OS 96 642 Binuclear +0.08161924668344495 0.035527389189407316 BR00118048 BRD4 final crispr J16 U2OS 96 595 Binuclear +0.0618925600667779 0.03616762510431038 BR00118046 S1PR4 final crispr L05 U2OS 96 1031 Binuclear +0.10477004477004477 0.03685390000492773 BR00118047 TUBB4B final crispr J13 U2OS 96 351 Binuclear +0.0765687212225015 0.03735467319867231 BR00118048 MET final crispr E20 U2OS 96 671 Binuclear +0.09089169536930732 0.03746797367536728 BR00118046 CHRM3 final crispr B17 U2OS 96 468 Binuclear +0.06633330892429362 0.03996342695099792 BR00118048 HTR3A final crispr O02 U2OS 96 877 Binuclear +0.06691480113018909 0.0401760459629009 BR00118045 BRAF final crispr F20 U2OS 96 856 Binuclear +0.08243578599952131 0.04047744071061134 BR00118047 RNASE1 final crispr I13 U2OS 96 564 Binuclear +0.14834616481323068 0.04118682540173556 BR00118046 PLK1 final crispr F13 U2OS 96 168 Binuclear +0.11347861178369653 0.04128883132865205 BR00118046 FFAR2 final crispr A24 U2OS 96 295 Binuclear +0.09915954808487186 0.04296100298721605 BR00118048 RPL3 final crispr K04 U2OS 96 382 Binuclear +0.08121485851230528 0.04406108212268776 BR00118048 AKT1 final crispr F06 U2OS 96 571 Binuclear +0.09207910540484572 0.04435587872104692 BR00118048 TNNC1 final crispr D09 U2OS 96 439 Binuclear +0.07121420532699763 0.04549122190754546 BR00118048 F10 final crispr H07 U2OS 96 726 Binuclear +0.06875 0.045559747020810754 BR00118045 CA14 final crispr C19 U2OS 96 800 Binuclear +0.06732348111658457 0.04589095528748957 BR00118045 HDAC6 final crispr K12 U2OS 96 812 Binuclear +0.0645879732739421 0.04719404716650423 BR00118045 GABRB2 final crispr D10 U2OS 96 898 Binuclear +0.07792207792207792 0.04745961835570677 BR00118046 S1PR2 final crispr J23 U2OS 96 616 Binuclear 0.2130890052356021 4.121343561569569e-08 BR00118048 RPL3 final crispr K04 U2OS 96 382 Elongated 0.19314396398505762 1.2901587883469764e-07 BR00118046 AURKB final crispr C13 U2OS 96 434 Elongated 0.10377133309464137 1.109429553554406e-06 BR00118047 RGS4 final crispr N11 U2OS 96 1323 Elongated @@ -949,6 +9409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2509031198686371 2.1529681667205155e-05 BR00118046 PLK1 final crispr G09 U2OS 96 175 Elongated 0.1971326164874552 3.7144615875310395e-05 BR00118045 PLK1 final crispr G09 U2OS 96 279 Elongated 0.11879895561357702 3.962590036750916e-05 BR00118045 PDE7A final crispr C22 U2OS 96 766 Elongated +0.10210010608814198 5.2544123515766195e-05 BR00118048 LPAR1 final crispr L01 U2OS 96 999 Elongated +0.11100387041424156 0.00011253981527586261 BR00118045 BRD4 final crispr M19 U2OS 96 786 Elongated +0.1466724286949006 0.00012202720085526004 BR00118046 KCNMA1 final crispr A07 U2OS 96 445 Elongated +0.10611552015586052 0.00013777909556737678 BR00118045 JAK1 final crispr M21 U2OS 96 836 Elongated +0.12390547054242354 0.00014330248492707052 BR00118047 PRKCE final crispr I17 U2OS 96 617 Elongated +0.23107356715141147 0.00017257010340727063 BR00118046 PLK1 final crispr F13 U2OS 96 168 Elongated +0.10103549024662714 0.00026223257681502683 BR00118046 LPAR1 final crispr L01 U2OS 96 864 Elongated +0.104051163664346 0.00026559954206389777 BR00118045 HDAC6 final crispr K12 U2OS 96 812 Elongated +0.10350714851649066 0.0002673130456525865 BR00118048 SIRT2 final crispr P01 U2OS 96 824 Elongated +0.2018867924528302 0.00029869790282765075 BR00118047 RPL23A final crispr G14 U2OS 96 210 Elongated +0.13637964756810872 0.0003062556524953029 BR00118048 AURKB final crispr C13 U2OS 96 466 Elongated +0.0938381660391122 0.00035394261838420267 BR00118046 CDK4 final crispr P03 U2OS 96 966 Elongated +0.08702295311195893 0.00047420916824116293 BR00118047 GPR119 final crispr P21 U2OS 96 1094 Elongated +0.12614636405743399 0.0005168748382412361 BR00118048 AGER final crispr K20 U2OS 96 510 Elongated +0.11144578313253012 0.0005184060052717231 BR00118047 GJB4 final crispr H01 U2OS 96 664 Elongated +0.11827239754867219 0.0005311693161486469 BR00118046 PPAT final crispr E13 U2OS 96 578 Elongated +0.11776491606693243 0.0005521663592964915 BR00118046 S1PR1 final crispr P23 U2OS 96 579 Elongated +0.10637690368951881 0.0007589077753673409 BR00118047 DHH final crispr K21 U2OS 96 682 Elongated +0.10078668894458369 0.0008159054024575196 BR00118047 OPRM1 final crispr C23 U2OS 96 756 Elongated +0.08378378378378379 0.0008215108759559069 BR00118047 KCNQ2 final crispr P13 U2OS 96 1110 Elongated +0.10344270373037706 0.000901329658666625 BR00118045 SIRT2 final crispr P01 U2OS 96 709 Elongated +0.11975748776297915 0.0009143722341861704 BR00118045 AURKB final crispr C13 U2OS 96 526 Elongated +0.11082175470619397 0.0009344200436851425 BR00118047 UGT1A9 final crispr J01 U2OS 96 618 Elongated +0.1104799004490613 0.0010670468266071745 BR00118047 BRD4 final crispr J16 U2OS 96 606 Elongated +0.10013351134846461 0.0010868947499457987 BR00118048 ABL1 final crispr C01 U2OS 96 749 Elongated +0.09909407323200427 0.001105069053591145 BR00118046 HBB final crispr F21 U2OS 96 754 Elongated +0.11042102120035832 0.001291101636712759 BR00118048 GPR55 final crispr H16 U2OS 96 595 Elongated +0.08298318942602065 0.0013227255807977498 BR00118047 PTK2B final crispr N15 U2OS 96 1044 Elongated +0.11111895683283905 0.001356625312039447 BR00118047 PDE7A final crispr C10 U2OS 96 584 Elongated +0.09703612840997253 0.0015077752531713474 BR00118046 SLC7A11 final crispr P05 U2OS 96 756 Elongated +0.0989010989010989 0.0016052531664315776 BR00118047 ALK final crispr G06 U2OS 96 728 Elongated +0.10276644939407671 0.0017422318687653894 BR00118047 PPAT final crispr G13 U2OS 96 657 Elongated +0.1249031007751938 0.0021472191831689437 BR00118047 RPL3 final crispr K04 U2OS 96 432 Elongated +0.11147300878783652 0.002166799368895978 BR00118046 FOXM1 final crispr A19 U2OS 96 536 Elongated +0.09682750948568704 0.00222343733346251 BR00118047 ATP5F1D final crispr G21 U2OS 96 710 Elongated +0.08487486398258977 0.002654629904829104 BR00118046 EDNRB final crispr K06 U2OS 96 919 Elongated +0.10038454049844237 0.002784241039885929 BR00118045 NAMPT final crispr D18 U2OS 96 640 Elongated +0.14892108319579436 0.0030423667153346326 BR00118046 HPGDS final crispr B19 U2OS 96 287 Elongated +0.08162786917692119 0.0032565452016101305 BR00118046 HSD11B1 final crispr O23 U2OS 96 949 Elongated +0.08747903526799423 0.0033673498536836983 BR00118046 SLCO2B1 final crispr I24 U2OS 96 822 Elongated +0.09513679315292138 0.0034639226254781974 BR00118048 HCK final crispr M23 U2OS 96 697 Elongated +0.09399815101663472 0.0037893528690455293 BR00118046 GJB4 final crispr N01 U2OS 96 699 Elongated +0.08736610851393602 0.004188323256169755 BR00118046 PAK1 final crispr N06 U2OS 96 797 Elongated +0.09191273663521109 0.004189673319423758 BR00118046 CACNB4 final crispr B01 U2OS 96 722 Elongated +0.09180032543003254 0.004275015806795766 BR00118048 HDAC3 final crispr K19 U2OS 96 720 Elongated +0.09497415471368793 0.004367164352931551 BR00118048 LCK final crispr O13 U2OS 96 670 Elongated +0.08362662028096124 0.004473672847847044 BR00118045 TNF final crispr I10 U2OS 96 859 Elongated +0.0958550929193131 0.0045404061437953865 BR00118048 ALK final crispr I15 U2OS 96 654 Elongated +0.09041079798863969 0.00460362649961244 BR00118048 F10 final crispr H07 U2OS 96 726 Elongated +0.10305013762071923 0.0048008251025047416 BR00118047 PDPK1 final crispr E16 U2OS 96 557 Elongated +0.09407698056801196 0.00480974203970017 BR00118046 CA5A final crispr M01 U2OS 96 672 Elongated +0.08657316372034148 0.004931767575068206 BR00118048 KCNN4 final crispr K01 U2OS 96 787 Elongated +0.09612403100775194 0.005137875466065032 BR00118047 HTR2C final crispr M12 U2OS 96 645 Elongated +0.0918914044213797 0.005158655082882312 BR00118045 LCK final crispr O13 U2OS 96 698 Elongated +0.08444093462363865 0.005245019141854494 BR00118047 PPARD final crispr N03 U2OS 96 819 Elongated +0.07930664107134695 0.005283996127540611 BR00118045 KRAS final crispr D21 U2OS 96 935 Elongated +0.08662420382165605 0.005511473757477613 BR00118046 LCK final crispr O15 U2OS 96 785 Elongated +0.07646474677259185 0.005530603854613868 BR00118047 SCNN1G final crispr P15 U2OS 96 1007 Elongated +0.0992746844068697 0.005620012638959264 BR00118047 S1PR2 final crispr J23 U2OS 96 589 Elongated +0.0940191353948607 0.005745954988651431 BR00118047 AKR1C1 final crispr B06 U2OS 96 654 Elongated +0.092008143463571 0.005756602137654824 BR00118047 GAA final crispr L18 U2OS 96 679 Elongated +0.10570009101941748 0.005783345193846439 BR00118047 GAA final crispr L17 U2OS 96 515 Elongated +0.09724473257698542 0.0058225349439050035 BR00118046 PTPN2 final crispr A15 U2OS 96 617 Elongated +0.08622810023991452 0.00587615895131388 BR00118047 CA14 final crispr C19 U2OS 96 772 Elongated +0.11190075253779339 0.006025530184479601 BR00118047 TUBB3 final crispr F19 U2OS 96 458 Elongated +0.08053691275167785 0.0060448840464979595 BR00118045 MAPK8 final crispr D07 U2OS 96 894 Elongated +0.08 0.006283654506781267 BR00118048 BRAF final crispr J10 U2OS 96 900 Elongated +0.08788772348923146 0.006415523422798317 BR00118047 PTGIS final crispr K17 U2OS 96 734 Elongated +0.09055670726440355 0.006655914477774346 BR00118047 JAK1 final crispr M21 U2OS 96 680 Elongated +0.1834319526627219 0.006680982573926605 BR00118047 PLK1 final crispr G09 U2OS 96 169 Elongated +0.10274353706557096 0.006728356220785786 BR00118045 MAPK14 final crispr A20 U2OS 96 528 Elongated +0.13149847094801223 0.0069502042571008196 BR00118047 TUBB final crispr J17 U2OS 96 327 Elongated +0.1016362228778273 0.007139256093716486 BR00118045 F10 final crispr H07 U2OS 96 537 Elongated +0.07623303541873552 0.007327489218008842 BR00118046 CCR1 final crispr O17 U2OS 96 950 Elongated +0.09089691266921192 0.008018423169772282 BR00118047 PLD1 final crispr F04 U2OS 96 659 Elongated +0.08387096774193549 0.00802850228843729 BR00118046 IMPDH1 final crispr F15 U2OS 96 775 Elongated +0.10934374984567825 0.008153922344845908 BR00118047 PORCN final crispr L13 U2OS 96 449 Elongated +0.09379505526779516 0.008356501295362128 BR00118047 PAK1 final crispr K10 U2OS 96 610 Elongated +0.08564897780053396 0.008376700382586099 BR00118047 ASIC1 final crispr J04 U2OS 96 739 Elongated +0.1114721521026908 0.008377114442372366 BR00118047 JAK1 final crispr J09 U2OS 96 433 Elongated +0.10093430920755399 0.008455529929403028 BR00118045 UGT1A9 final crispr B18 U2OS 96 525 Elongated +0.09017223910840932 0.008551542064512694 BR00118047 FPR1 final crispr N22 U2OS 96 660 Elongated +0.08299338633528865 0.008632684275002371 BR00118045 FLT3 final crispr G16 U2OS 96 777 Elongated +0.08536585365853659 0.0092069431241169 BR00118046 HSD11B1 final crispr O01 U2OS 96 738 Elongated +0.0926517571884984 0.009241404693707577 BR00118047 ATP5F1D final crispr E15 U2OS 96 626 Elongated +0.07570847329327719 0.009294633171359545 BR00118046 CYP2A6 final crispr C07 U2OS 96 920 Elongated +0.11009174311926606 0.010093224455038885 BR00118047 ICAM1 final crispr I12 U2OS 96 436 Elongated +0.08775882111298541 0.010323451460829988 BR00118048 CDK2 final crispr L19 U2OS 96 676 Elongated +0.08109556838583847 0.010493936604776901 BR00118047 DCK final crispr J08 U2OS 96 788 Elongated +0.08290681405655832 0.010539353435264666 BR00118047 AKT1 final crispr F06 U2OS 96 749 Elongated 0.15642036447300123 7.39936896695841e-07 BR00118046 CACNB4 final crispr I23 U2OS 96 599 Grape 0.15892857142857142 1.3725135389061338e-06 BR00118047 AURKB final crispr C13 U2OS 96 560 Grape 0.16963420993816583 6.015011393340463e-06 BR00118046 AURKB final crispr C13 U2OS 96 434 Grape @@ -959,6 +9509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.12056444847142521 2.3341371221147323e-05 BR00118046 SLC7A11 final crispr A05 U2OS 96 774 Grape 0.1415929203539823 2.3410569029320324e-05 BR00118047 DDR2 final crispr A03 U2OS 96 565 Grape 0.15040650406504066 2.3508043593902813e-05 BR00118048 ANXA1 final crispr F24 U2OS 96 492 Grape +0.12001219119863188 2.748019125749868e-05 BR00118045 KCNJ1 final crispr F03 U2OS 96 770 Grape +0.14605768607210567 3.1702144319294216e-05 BR00118048 KCNQ2 final crispr A16 U2OS 96 513 Grape +0.13829787234042554 4.030281305041811e-05 BR00118045 FOXM1 final crispr A19 U2OS 96 564 Grape +0.13409373987437537 5.25822536360267e-05 BR00118046 S1PR1 final crispr P23 U2OS 96 579 Grape +0.12965964343598055 6.125820740044151e-05 BR00118046 BRD4 final crispr J16 U2OS 96 617 Grape +0.15734758755063324 9.159972596665348e-05 BR00118047 MAPK8 final crispr D13 U2OS 96 394 Grape +0.11207603341330484 0.00011172862205483628 BR00118047 CA14 final crispr C19 U2OS 96 772 Grape +0.10396734116100656 0.00012078078807062538 BR00118046 HTR3A final crispr O02 U2OS 96 889 Grape +0.11619023023897972 0.00012639771297739518 BR00118047 ATP5F1D final crispr G21 U2OS 96 710 Grape +0.1323545822290417 0.00014017020573029134 BR00118046 FOXM1 final crispr A19 U2OS 96 536 Grape +0.12788984737889847 0.00021267916048774504 BR00118046 CHEK2 final crispr M07 U2OS 96 550 Grape +0.11412739920788058 0.00023342405686959766 BR00118046 IL1B final crispr H18 U2OS 96 687 Grape +0.11299435028248588 0.0002342050420771252 BR00118047 ERBB2 final crispr H12 U2OS 96 708 Grape +0.11732148875728249 0.00023427782372436375 BR00118046 PIK3CG final crispr I08 U2OS 96 645 Grape +0.10743950643662198 0.00023498956035039668 BR00118046 ATP5F1D final crispr E15 U2OS 96 776 Grape +0.1040392961460686 0.0002428000116549584 BR00118048 SIRT2 final crispr P01 U2OS 96 824 Grape +0.128793027767158 0.0002657043623857768 BR00118046 DHH final crispr F05 U2OS 96 531 Grape +0.0987666945672195 0.00030931423484632103 BR00118045 CYP1A2 final crispr K22 U2OS 96 889 Grape +0.1649661967186083 0.0003732608799732303 BR00118048 FOXM1 final crispr A19 U2OS 96 312 Grape +0.09980618999344028 0.0005257749461379241 BR00118045 HTR3A final crispr O20 U2OS 96 820 Grape +0.1776061776061776 0.0005507470715168763 BR00118045 FFAR2 final crispr A24 U2OS 96 259 Grape +0.08636089910866436 0.0005719150040783875 BR00118045 GLRA3 final crispr E21 U2OS 96 1079 Grape +0.08558558558558559 0.0005850789111361399 BR00118047 KCNQ2 final crispr P13 U2OS 96 1110 Grape +0.11801160175501124 0.0006267518870347993 BR00118046 GAA final crispr L17 U2OS 96 569 Grape +0.13367227617062383 0.0006285900643673211 BR00118046 KCNMA1 final crispr A07 U2OS 96 445 Grape +0.09567198177676538 0.0006419447721223467 BR00118045 KDR final crispr J02 U2OS 96 878 Grape +0.11058132466143716 0.000725395121680856 BR00118046 ADRA2B final crispr H22 U2OS 96 639 Grape +0.09661994294120525 0.0007455073720457856 BR00118046 VEGFA final crispr H02 U2OS 96 834 Grape +0.11902053584123824 0.0007999419304796979 BR00118046 CDK2 final crispr F08 U2OS 96 546 Grape +0.11604666115550656 0.0008057444960479253 BR00118046 CTSG final crispr L12 U2OS 96 570 Grape +0.11256117455138662 0.0008386758273079604 BR00118045 ITGB2 final crispr A17 U2OS 96 613 Grape +0.10927301540137671 0.0009276854608212143 BR00118047 KDR final crispr O18 U2OS 96 636 Grape +0.11915975342781426 0.001013220639105854 BR00118046 PLA2G1B final crispr J11 U2OS 96 526 Grape +0.13264500112841346 0.0010759962778294292 BR00118048 JAK1 final crispr J09 U2OS 96 420 Grape +0.0997394403350668 0.0010945343614888285 BR00118046 CA14 final crispr C19 U2OS 96 746 Grape +0.09787917477302205 0.0011364928674622826 BR00118046 TGM2 final crispr B09 U2OS 96 771 Grape +0.09248554913294797 0.001216244743606927 BR00118047 PAK1 final crispr N06 U2OS 96 865 Grape +0.10542168674698796 0.0012376809340751598 BR00118047 GJB4 final crispr H01 U2OS 96 664 Grape +0.09792862576941697 0.0012430170011011206 BR00118046 KCNJ1 final crispr E14 U2OS 96 760 Grape +0.10272857302350663 0.0012485340476283669 BR00118045 PPAT final crispr E13 U2OS 96 687 Grape +0.09806604634190841 0.0012640751722925144 BR00118046 KCNMA1 final crispr E23 U2OS 96 754 Grape +0.08540218470705065 0.0012853349436114793 BR00118047 SCNN1G final crispr P15 U2OS 96 1007 Grape +0.11248944619906814 0.0013259924657411444 BR00118046 TUBB3 final crispr F19 U2OS 96 566 Grape +0.10289855072463767 0.0013330608755289827 BR00118047 HTR3A final crispr O20 U2OS 96 690 Grape +0.0985352862849534 0.0013529969129741069 BR00118045 TGM2 final crispr B09 U2OS 96 751 Grape +0.09699445457175422 0.0014707345990978185 BR00118046 PRKCE final crispr I17 U2OS 96 757 Grape +0.09338271074212394 0.001479228538781853 BR00118046 AVPR1A final crispr D05 U2OS 96 818 Grape +0.12276985038179068 0.001498713781454558 BR00118046 CHRM3 final crispr B17 U2OS 96 468 Grape +0.08009426157090507 0.001582235738888429 BR00118045 CYP2A6 final crispr C07 U2OS 96 1102 Grape +0.0989010989010989 0.0016052531664315776 BR00118046 GLRA3 final crispr E21 U2OS 96 728 Grape +0.10422973980957395 0.0017055230195052362 BR00118047 S1PR2 final crispr K02 U2OS 96 642 Grape +0.0898083897696752 0.0017631271872595431 BR00118047 GPR119 final crispr G23 U2OS 96 863 Grape +0.09529385390080707 0.0017987349701784625 BR00118047 MMP2 final crispr E07 U2OS 96 760 Grape +0.1229509756352808 0.0018099196335666105 BR00118047 TUBB3 final crispr F19 U2OS 96 458 Grape +0.11111467965044017 0.001815785704491886 BR00118045 KCNN4 final crispr A22 U2OS 96 557 Grape +0.09503984978379008 0.001824851958179094 BR00118048 CACNB4 final crispr I23 U2OS 96 766 Grape +0.10678372352285395 0.0019432028167227489 BR00118046 RNASE1 final crispr I13 U2OS 96 600 Grape +0.10339506172839506 0.0019472311517755557 BR00118046 MAPK8 final crispr D13 U2OS 96 648 Grape +0.09078495676485508 0.0019660119676591656 BR00118045 ADH1C final crispr D02 U2OS 96 824 Grape +0.09873060648801128 0.001980567585794943 BR00118047 CHEK2 final crispr M07 U2OS 96 709 Grape +0.12057953818630132 0.002058150896735108 BR00118048 AURKB final crispr C13 U2OS 96 466 Grape +0.08029268875621068 0.0022118179946352423 BR00118045 P2RY12 final crispr O21 U2OS 96 1045 Grape +0.09843081312410841 0.0022322993518374377 BR00118045 CACNA2D3 final crispr N24 U2OS 96 701 Grape +0.0903496287174728 0.002241947601538503 BR00118047 PPARD final crispr N03 U2OS 96 819 Grape +0.0847863891678756 0.0022446077600813312 BR00118045 CA5A final crispr I02 U2OS 96 928 Grape +0.1805940594059406 0.0022767723699262886 BR00118048 PLK1 final crispr G09 U2OS 96 200 Grape +0.10090361445783133 0.002302407861118841 BR00118046 CHRM2 final crispr B07 U2OS 96 664 Grape +0.09840810419681621 0.0024674172949250427 BR00118047 FFAR4 final crispr E04 U2OS 96 691 Grape +0.09002433090024331 0.0025450274162567114 BR00118047 CYP2A6 final crispr C07 U2OS 96 822 Grape +0.08110203922766236 0.0025463329665098683 BR00118048 LPAR1 final crispr L01 U2OS 96 999 Grape +0.10128930978835397 0.002570558459430917 BR00118046 DCK final crispr J08 U2OS 96 639 Grape +0.10362381363244176 0.0025738341641956927 BR00118046 DDR2 final crispr B03 U2OS 96 608 Grape +0.09517067344737247 0.0025949927201790518 BR00118046 HIF1A final crispr A01 U2OS 96 721 Grape +0.09068425781434719 0.0026052592530196785 BR00118046 GPR119 final crispr G23 U2OS 96 795 Grape +0.0898404431521219 0.0026556560352397713 BR00118047 GABRB2 final crispr D10 U2OS 96 807 Grape +0.08574610244988864 0.0027020924331051938 BR00118045 GABRB2 final crispr D10 U2OS 96 898 Grape +0.07934382637745852 0.002803210956907919 BR00118046 S1PR4 final crispr L05 U2OS 96 1031 Grape +0.09404971417800281 0.002832340058483578 BR00118046 BAX final crispr E06 U2OS 96 731 Grape +0.10385259631490787 0.003176677849171907 BR00118047 GRIN2A final crispr A23 U2OS 96 597 Grape +0.09069256573229031 0.003200246495211688 BR00118047 PTGIR final crispr G08 U2OS 96 767 Grape +0.1085137496879124 0.0035712976051551454 BR00118046 AVPR1A final crispr J07 U2OS 96 529 Grape +0.11467466133688652 0.0035915339273790443 BR00118048 ALDH2 final crispr A10 U2OS 96 474 Grape +0.09565217391304348 0.0036066896998305214 BR00118047 PTPN2 final crispr A15 U2OS 96 690 Grape +0.09860155493181649 0.003707817147859567 BR00118046 S1PR4 final crispr H05 U2OS 96 634 Grape +0.09873546026526904 0.0037164833104593557 BR00118046 PPARD final crispr N03 U2OS 96 635 Grape +0.08402804600660915 0.004063361713745225 BR00118045 SLC7A11 final crispr A05 U2OS 96 863 Grape +0.08012308046878722 0.004111103950118285 BR00118045 PAK1 final crispr N06 U2OS 96 949 Grape +0.07460555872420639 0.004130933949388034 BR00118047 GPR119 final crispr P21 U2OS 96 1094 Grape +0.107869803708237 0.004500258933716675 BR00118045 RPL3 final crispr H11 U2OS 96 513 Grape +0.12419967480991223 0.004639224330856251 BR00118045 CCND1 final crispr B23 U2OS 96 383 Grape 0.28035714285714286 8.794617061320582e-20 BR00118047 AURKB final crispr C13 U2OS 96 560 Hole 0.2874703334362129 2.0821630417819807e-16 BR00118046 AURKB final crispr C13 U2OS 96 434 Hole 0.24340710286285192 3.375686784848791e-14 BR00118045 AURKB final crispr C13 U2OS 96 526 Hole @@ -969,6 +9609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2923267326732673 4.749407593864096e-08 BR00118048 PLK1 final crispr G09 U2OS 96 200 Hole 0.2831536388140162 6.271712019351586e-08 BR00118047 RPL23A final crispr G14 U2OS 96 210 Hole 0.18502149325988063 7.532064947611407e-08 BR00118046 TUBB3 final crispr K11 U2OS 96 490 Hole +0.24377224199288255 8.703965489671095e-08 BR00118046 RPL23A final crispr G14 U2OS 96 278 Hole +0.19601173657900456 1.0133928327551871e-07 BR00118047 PPAT final crispr E13 U2OS 96 430 Hole +0.1464315345671278 1.1494225829478913e-07 BR00118045 KCNJ1 final crispr F03 U2OS 96 770 Hole +0.12711022840119166 1.6572788464839537e-07 BR00118047 SCNN1G final crispr P15 U2OS 96 1007 Hole +0.3144224196855776 3.039932645119565e-07 BR00118046 RPL23A final crispr M18 U2OS 96 152 Hole +0.19676837270341208 5.848748301455366e-07 BR00118048 TUBB3 final crispr K11 U2OS 96 384 Hole +0.20861847733105218 7.399698128681687e-07 BR00118045 RPL23A final crispr M18 U2OS 96 334 Hole +0.11441441441441441 9.53843087966789e-07 BR00118047 KCNQ2 final crispr P13 U2OS 96 1110 Hole +0.1883291457286432 1.0586457557628419e-06 BR00118045 RPL23A final crispr G14 U2OS 96 400 Hole +0.15876712860525602 1.3354790430287638e-06 BR00118048 PPAT final crispr E13 U2OS 96 554 Hole +0.1323839712203973 1.3692477977501525e-06 BR00118045 CDK4 final crispr P03 U2OS 96 797 Hole +0.1504 1.3891669024932686e-06 BR00118045 CSF1R final crispr J15 U2OS 96 625 Hole +0.18160377358490565 1.590466069805037e-06 BR00118045 TUBB4B final crispr J13 U2OS 96 424 Hole +0.11285963025468705 1.6524950719881229e-06 BR00118047 GPR119 final crispr P21 U2OS 96 1094 Hole +0.1636175013411594 2.4992313888253295e-06 BR00118047 ERBB2 final crispr I11 U2OS 96 503 Hole +0.1323005848944647 3.119747877555124e-06 BR00118045 HSP90AB1 final crispr B04 U2OS 96 752 Hole +0.1570097560284893 3.5375622348195474e-06 BR00118046 DHH final crispr F05 U2OS 96 531 Hole +0.15115275098741618 3.598296165688213e-06 BR00118046 CTSG final crispr L12 U2OS 96 570 Hole +0.13071895424836602 4.08732913480178e-06 BR00118045 DCK final crispr I07 U2OS 96 765 Hole +0.14017494605443281 4.22782117752983e-06 BR00118047 S1PR1 final crispr P23 U2OS 96 658 Hole +0.21505376344086022 4.607722311801033e-06 BR00118045 PLK1 final crispr G09 U2OS 96 279 Hole +0.14816036908552047 5.05488385859851e-06 BR00118046 S1PR1 final crispr P23 U2OS 96 579 Hole +0.1458425106269553 5.127873013036109e-06 BR00118046 CACNB4 final crispr I23 U2OS 96 599 Hole +0.14012143627068027 6.384325023197228e-06 BR00118045 CYP3A4 final crispr D04 U2OS 96 634 Hole +0.21073682570189337 7.034303225914535e-06 BR00118048 RPL23A final crispr G14 U2OS 96 278 Hole +0.16451655868558002 7.1280531168336856e-06 BR00118047 TUBB3 final crispr F19 U2OS 96 458 Hole +0.13021604469139555 7.133386149722166e-06 BR00118045 KDR final crispr O18 U2OS 96 731 Hole +0.10768666703330951 9.871503472969567e-06 BR00118047 PTK2B final crispr N15 U2OS 96 1044 Hole +0.1310453336923232 1.2508891621275202e-05 BR00118045 S1PR1 final crispr A18 U2OS 96 688 Hole +0.12362944885940944 1.6040842315365442e-05 BR00118045 DYRK1B final crispr N16 U2OS 96 756 Hole +0.14900204936291545 1.6664471410141563e-05 BR00118048 CYP3A4 final crispr D04 U2OS 96 522 Hole +0.11839398928314884 1.7520023193172316e-05 BR00118045 CYP2A6 final crispr O04 U2OS 96 821 Hole +0.12140992167101827 2.446033276102799e-05 BR00118045 PDE7A final crispr C22 U2OS 96 766 Hole +0.1623642513797401 2.994714669932749e-05 BR00118047 DYRK1B final crispr N16 U2OS 96 411 Hole +0.12117177097203728 3.188947451472237e-05 BR00118045 HIF1A final crispr M24 U2OS 96 751 Hole +0.11161731207289294 3.493888579847007e-05 BR00118045 KDR final crispr J02 U2OS 96 878 Hole +0.11230727824983659 4.446012772045463e-05 BR00118045 GJB4 final crispr N01 U2OS 96 839 Hole +0.1480232227120194 4.7536075996824136e-05 BR00118047 USP1 final crispr N12 U2OS 96 481 Hole +0.11469388653566161 4.998676707761491e-05 BR00118045 FLT3 final crispr J20 U2OS 96 797 Hole +0.1174934725848564 5.023579380910524e-05 BR00118046 CDC25A final crispr D06 U2OS 96 766 Hole +0.118508655126498 5.160550130561589e-05 BR00118045 TGM2 final crispr B09 U2OS 96 751 Hole +0.1123745119088346 5.262316734400391e-05 BR00118045 ADH1C final crispr D02 U2OS 96 824 Hole +0.14776166598906806 5.7652167203635184e-05 BR00118045 TUBB3 final crispr K11 U2OS 96 471 Hole +0.11926736725004469 6.823227251871242e-05 BR00118047 ATP5F1D final crispr G21 U2OS 96 710 Hole +0.1117211708208338 7.749095133998649e-05 BR00118045 KCNN1 final crispr D01 U2OS 96 804 Hole +0.11748960950710347 9.07633676803076e-05 BR00118045 CACNB4 final crispr B01 U2OS 96 712 Hole +0.10985151171805116 9.106122346044266e-05 BR00118045 HTR3A final crispr O20 U2OS 96 820 Hole +0.11196689237080806 9.197339387047502e-05 BR00118046 PRKCE final crispr K05 U2OS 96 783 Hole +0.11920451085800557 9.321454119246704e-05 BR00118045 SSTR2 final crispr P10 U2OS 96 691 Hole +0.12603846591555706 0.00011171365392567039 BR00118045 RGS4 final crispr N11 U2OS 96 609 Hole +0.10192779823680392 0.00011493908914346213 BR00118045 CA5A final crispr I02 U2OS 96 928 Hole +0.11 0.00012336231225394914 BR00118045 CA14 final crispr C19 U2OS 96 800 Hole +0.1185528829285408 0.00012474510663222776 BR00118045 COMT final crispr A12 U2OS 96 678 Hole +0.15717828602920914 0.000140527778957364 BR00118048 RPL3 final crispr K04 U2OS 96 382 Hole +0.13350551520043044 0.00014136596445099542 BR00118047 CYP3A4 final crispr D04 U2OS 96 531 Hole +0.17501650165016502 0.00015836614230807787 BR00118047 TUBB3 final crispr K11 U2OS 96 303 Hole +0.09408325634626256 0.00017700259055180627 BR00118045 P2RY12 final crispr O21 U2OS 96 1045 Hole +0.12369565217391304 0.00018000619342512493 BR00118046 JAK1 final crispr J09 U2OS 96 600 Hole +0.10870032720932464 0.00018104506467294735 BR00118045 TUBB4B final crispr C04 U2OS 96 777 Hole +0.12883496759182317 0.00019206917309080835 BR00118048 GAA final crispr L18 U2OS 96 547 Hole +0.11391631926083516 0.00019742906552470542 BR00118045 LCK final crispr O13 U2OS 96 698 Hole +0.10826074216148539 0.00020507437827803527 BR00118045 HTR3A final crispr O02 U2OS 96 774 Hole +0.15132287340409167 0.00020633385459205574 BR00118047 MAPK8 final crispr D13 U2OS 96 394 Hole +0.13092666205784076 0.00020708626168494716 BR00118046 PLA2G1B final crispr J11 U2OS 96 526 Hole +0.12768626988494902 0.0002075633961921234 BR00118046 IGF1R final crispr E19 U2OS 96 553 Hole +0.10385021478470906 0.00022888224085234715 BR00118045 SLC29A1 final crispr E03 U2OS 96 833 Hole +0.11723241369348548 0.00024358721306828556 BR00118046 PIK3CG final crispr I08 U2OS 96 645 Hole +0.12326915174290837 0.0002628435115749932 BR00118046 PPAT final crispr E13 U2OS 96 578 Hole +0.11996269809916178 0.000263943580746181 BR00118045 ADRA2B final crispr H22 U2OS 96 611 Hole +0.11203382922355819 0.00027279145840952387 BR00118046 KDR final crispr O18 U2OS 96 700 Hole +0.10565737711706488 0.00030559533810260383 BR00118046 KRAS final crispr D21 U2OS 96 779 Hole +0.11632035006613184 0.00032450028338439736 BR00118046 PPARD final crispr N03 U2OS 96 635 Hole +0.11577774476303669 0.0003397835200943511 BR00118047 KDR final crispr O18 U2OS 96 636 Hole +0.12136752136752137 0.00035698671535851765 BR00118046 HSP90AB1 final crispr B04 U2OS 96 585 Hole +0.10406247258050365 0.00036489847644355464 BR00118045 BRD4 final crispr M19 U2OS 96 786 Hole +0.12052361595044522 0.00040335894142681973 BR00118047 P3H1 final crispr N02 U2OS 96 576 Hole +0.106251630293018 0.0004097790729988649 BR00118045 GAA final crispr L18 U2OS 96 742 Hole +0.12162985213600809 0.0004359784821076922 BR00118046 CDK2 final crispr L19 U2OS 96 561 Hole +0.10350931173553282 0.00043722494794814533 BR00118045 FLT3 final crispr G16 U2OS 96 777 Hole +0.09542341887586729 0.0004382117726166812 BR00118045 LYN final crispr F22 U2OS 96 916 Hole +0.11014492753623188 0.0004579383614754192 BR00118047 HTR3A final crispr O20 U2OS 96 690 Hole +0.10514264385513457 0.00046953009936294584 BR00118046 CA14 final crispr C19 U2OS 96 746 Hole +0.1111928735642691 0.0004863161150565283 BR00118046 NAMPT final crispr I09 U2OS 96 662 Hole +0.12186379928315412 0.0004970856696586393 BR00118046 ASIC1 final crispr J04 U2OS 96 558 Hole +0.10559603319166161 0.0005196513730740587 BR00118045 ASIC1 final crispr J04 U2OS 96 732 Hole +0.08824789245841877 0.0005226684235633154 BR00118045 OPRM1 final crispr C23 U2OS 96 1050 Hole +0.11761113432547973 0.0005394910368592408 BR00118047 NAMPT final crispr I09 U2OS 96 587 Hole +0.12751610061978297 0.0005543030782359403 BR00118048 HSP90AB1 final crispr B04 U2OS 96 498 Hole +0.1123464656896135 0.0005582633043308171 BR00118046 ADRA2B final crispr H22 U2OS 96 639 Hole +0.09888790820829656 0.0005604676031388119 BR00118045 CA5A final crispr M01 U2OS 96 825 Hole 0.34517512585008675 1.4409305104845993e-23 BR00118046 AURKB final crispr C13 U2OS 96 434 Interphase 0.28035714285714286 8.794617061320582e-20 BR00118047 AURKB final crispr C13 U2OS 96 560 Interphase 0.22191235346122606 7.071788596594583e-12 BR00118045 AURKB final crispr C13 U2OS 96 526 Interphase @@ -979,6 +9709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2767821782178218 2.833234729098874e-07 BR00118048 PLK1 final crispr G09 U2OS 96 200 Interphase 0.12826975184887116 4.608817905582268e-07 BR00118045 LYN final crispr F22 U2OS 96 916 Interphase 0.14699494646283998 5.65682893590749e-07 BR00118045 PPAT final crispr E13 U2OS 96 687 Interphase +0.1264236902050114 1.5621428213077422e-06 BR00118045 KDR final crispr J02 U2OS 96 878 Interphase +0.12925715768736212 1.8988326206943316e-06 BR00118045 ADH1C final crispr D02 U2OS 96 824 Interphase +0.121260415504222 2.1239955331100835e-06 BR00118045 CA5A final crispr I02 U2OS 96 928 Interphase +0.21505376344086022 4.607722311801033e-06 BR00118045 PLK1 final crispr G09 U2OS 96 279 Interphase +0.1437981287483101 1.0689261662119735e-05 BR00118046 PPAT final crispr E13 U2OS 96 578 Interphase +0.12603098857075526 1.4630681393639922e-05 BR00118046 ADH1C final crispr P04 U2OS 96 736 Interphase +0.10434115154272898 2.0853213066822983e-05 BR00118045 P2RY12 final crispr O21 U2OS 96 1045 Interphase +0.1439792985288079 2.73357314529405e-05 BR00118046 DHH final crispr F05 U2OS 96 531 Interphase +0.1172709062493121 2.9859352983742838e-05 BR00118045 FLT3 final crispr J20 U2OS 96 797 Interphase +0.19437261578637446 4.169965640056064e-05 BR00118046 RPL23A final crispr G14 U2OS 96 278 Interphase +0.12031209165647574 6.0162516289446895e-05 BR00118045 IL1B final crispr H06 U2OS 96 709 Interphase +0.25598086124401914 6.0621264788266035e-05 BR00118046 RPL23A final crispr M18 U2OS 96 152 Interphase +0.19542268509322058 6.29552486034785e-05 BR00118047 RPL23A final crispr M18 U2OS 96 262 Interphase +0.11671777411598663 7.028042951476642e-05 BR00118048 PAK4 final crispr G22 U2OS 96 741 Interphase +0.12349397590361445 7.856561611761915e-05 BR00118047 GJB4 final crispr H01 U2OS 96 664 Interphase +0.12406103980599752 9.588405867034207e-05 BR00118046 IL1B final crispr H06 U2OS 96 636 Interphase +0.09385697936913445 0.00011195326714585384 BR00118045 CYP2A6 final crispr C07 U2OS 96 1102 Interphase +0.08928123406073807 0.00012096391115356277 BR00118045 PTGIR final crispr G08 U2OS 96 1204 Interphase +0.11110760248691283 0.00016162483242597353 BR00118046 HBB final crispr F21 U2OS 96 754 Interphase +0.11251761232751102 0.00017321396573874515 BR00118048 KCNK1 final crispr C17 U2OS 96 732 Interphase +0.10611843282247004 0.00017854847421481783 BR00118045 HTR3A final crispr O20 U2OS 96 820 Interphase +0.13093386334831203 0.00020672957412525987 BR00118046 PLA2G1B final crispr J11 U2OS 96 526 Interphase +0.09496834820862737 0.00021690017626513556 BR00118048 LPAR1 final crispr L01 U2OS 96 999 Interphase +0.12262734810117704 0.0002211699284383229 BR00118046 CACNB4 final crispr I23 U2OS 96 599 Interphase +0.09587852261877944 0.0002450049011360492 BR00118046 CDK4 final crispr P03 U2OS 96 966 Interphase +0.09247544219065415 0.0002678903049552805 BR00118045 CACNG1 final crispr L02 U2OS 96 1033 Interphase +0.11859027160005711 0.0003503954379516822 BR00118046 GJB4 final crispr H01 U2OS 96 604 Interphase +0.10040314202604118 0.0003931893325131117 BR00118048 RET final crispr I03 U2OS 96 833 Interphase +0.21628899835796386 0.0003939922368682915 BR00118046 PLK1 final crispr G09 U2OS 96 175 Interphase +0.09862131563117642 0.0004024098781291418 BR00118046 LPAR1 final crispr L01 U2OS 96 864 Interphase +0.1137271895613655 0.0004496881499478986 BR00118046 PIK3CG final crispr I08 U2OS 96 645 Interphase +0.12608825283243888 0.0004639347093338093 BR00118047 S1PR1 final crispr A18 U2OS 96 520 Interphase +0.1051930758988016 0.0004871496416848665 BR00118045 TGM2 final crispr B09 U2OS 96 751 Interphase +0.09899422279752165 0.0004915633170081966 BR00118045 GJB4 final crispr N01 U2OS 96 839 Interphase +0.14350356355432498 0.0005152462325210025 BR00118047 MAPK8 final crispr D13 U2OS 96 394 Interphase +0.09824561403508772 0.0005167433187833995 BR00118046 SSTR2 final crispr C02 U2OS 96 855 Interphase +0.11991641111240506 0.0005928436469004068 BR00118048 PPAT final crispr E13 U2OS 96 554 Interphase +0.08935662901598256 0.0006419137593565457 BR00118045 P3H1 final crispr N02 U2OS 96 992 Interphase +0.11879432624113476 0.0006907053155963723 BR00118045 AKT1 final crispr F06 U2OS 96 564 Interphase +0.12575017737156213 0.0007405046502724367 BR00118046 TUBB3 final crispr K11 U2OS 96 490 Interphase +0.09515322755922626 0.0007652083081118866 BR00118045 BRAF final crispr F20 U2OS 96 856 Interphase +0.09902361960012432 0.000809971361260633 BR00118045 CACNB4 final crispr I23 U2OS 96 788 Interphase +0.08738828202581926 0.0009091432759755657 BR00118047 SCNN1G final crispr P15 U2OS 96 1007 Interphase +0.1169276708692767 0.000951958119992827 BR00118046 CHEK2 final crispr M07 U2OS 96 550 Interphase +0.10127828963351959 0.0009921559434362098 BR00118045 S100B final crispr D22 U2OS 96 733 Interphase +0.10669157057008283 0.0010162408197888935 BR00118047 S1PR1 final crispr P23 U2OS 96 658 Interphase +0.12149061717519236 0.001068017619762306 BR00118046 FGF1 final crispr J12 U2OS 96 503 Interphase +0.17054263565891473 0.001077841612419884 BR00118045 PLK1 final crispr F13 U2OS 96 258 Interphase +0.1222298714922633 0.0010979990299410543 BR00118048 ANXA1 final crispr F24 U2OS 96 492 Interphase +0.09678004135187308 0.0011275108684312605 BR00118046 PRKCE final crispr K05 U2OS 96 783 Interphase +0.12552920246215904 0.0012436879760152914 BR00118047 TUBB3 final crispr F19 U2OS 96 458 Interphase +0.08739732675604073 0.0012863213486145493 BR00118045 PAK1 final crispr N06 U2OS 96 949 Interphase +0.09643970270918245 0.0013624496544474341 BR00118045 HTR3A final crispr O02 U2OS 96 774 Interphase +0.0960418781048021 0.0014379257612941677 BR00118046 ATP5F1D final crispr E15 U2OS 96 776 Interphase +0.10113540790580319 0.0014865912601513189 BR00118048 HCK final crispr M23 U2OS 96 697 Interphase +0.09820220483256598 0.0015698245985661203 BR00118046 BAX final crispr E06 U2OS 96 731 Interphase +0.18104222821203952 0.0015859567652307908 BR00118047 RPL23A final crispr G14 U2OS 96 210 Interphase +0.10696920583468396 0.0017043095812733161 BR00118046 BRD4 final crispr J16 U2OS 96 617 Interphase +0.08906426155580609 0.0017497527204052544 BR00118045 MME final crispr H08 U2OS 96 887 Interphase +0.11228186804055176 0.0017661252392871952 BR00118048 PDPK1 final crispr E16 U2OS 96 547 Interphase +0.09976046768581276 0.001775870295900627 BR00118046 OPRM1 final crispr P22 U2OS 96 696 Interphase +0.08595328468161677 0.0018557298605120685 BR00118047 EDNRB final crispr K06 U2OS 96 931 Interphase +0.10929549003398549 0.0019363675065375574 BR00118046 CTSG final crispr L12 U2OS 96 570 Interphase +0.09568389734092761 0.0020022707527947384 BR00118046 CA14 final crispr C19 U2OS 96 746 Interphase +0.08729281767955802 0.002013366349822626 BR00118045 DDR2 final crispr B03 U2OS 96 905 Interphase +0.11355714944117985 0.002018454786759334 BR00118046 FLT3 final crispr G16 U2OS 96 526 Interphase +0.07784499450189027 0.0020669302763283415 BR00118045 CCR1 final crispr G02 U2OS 96 1124 Interphase +0.08986463476928316 0.0021166296479963763 BR00118046 CHRM2 final crispr O22 U2OS 96 839 Interphase +0.07888825515872153 0.002119681813154036 BR00118047 GPR119 final crispr P21 U2OS 96 1094 Interphase +0.08488826488826488 0.0023627078254253166 BR00118045 HDAC3 final crispr K19 U2OS 96 925 Interphase +0.11918980285018091 0.002373703828782956 BR00118047 CDC25A final crispr D06 U2OS 96 467 Interphase +0.10185185185185185 0.0023922169631571504 BR00118046 MAPK8 final crispr D13 U2OS 96 648 Interphase +0.08952404346656373 0.0024065680914274615 BR00118048 S1PR4 final crispr L05 U2OS 96 828 Interphase +0.11760273729745063 0.002518300378798881 BR00118046 HRH4 final crispr H24 U2OS 96 474 Interphase +0.10138696627677314 0.0025289176091143756 BR00118046 DCK final crispr J08 U2OS 96 639 Interphase +0.08021911527697777 0.0026749324534270868 BR00118048 IGF1R final crispr M22 U2OS 96 1017 Interphase +0.09279294274300932 0.0026853358783741482 BR00118046 KCNN4 final crispr K01 U2OS 96 751 Interphase +0.19414741944682065 0.002931098358472775 BR00118046 PLK1 final crispr F13 U2OS 96 168 Interphase +0.08286256227432698 0.0029693551149868763 BR00118045 GPR55 final crispr C21 U2OS 96 935 Interphase +0.08966267613827543 0.0029950577751776774 BR00118045 CDK4 final crispr P03 U2OS 96 797 Interphase +0.08246433174305288 0.003017145633518993 BR00118045 DHH final crispr K21 U2OS 96 940 Interphase +0.10231768145854833 0.003037603857571151 BR00118047 GRIN2A final crispr P09 U2OS 96 608 Interphase +0.08481566208718293 0.003107275760381725 BR00118046 HTR3A final crispr O02 U2OS 96 889 Interphase +0.08935857321652065 0.003143232844930878 BR00118047 SSTR2 final crispr C02 U2OS 96 800 Interphase +0.1157227105819517 0.003150208220735595 BR00118046 DCK final crispr I07 U2OS 96 473 Interphase +0.09553248028164246 0.0032599386184866005 BR00118046 IL1B final crispr H18 U2OS 96 687 Interphase +0.0915032679738562 0.0032900655915561535 BR00118045 ATM final crispr F14 U2OS 96 765 Interphase +0.10897518831579553 0.0034313046140806297 BR00118046 BAX final crispr L14 U2OS 96 527 Interphase +0.07567567567567568 0.003458846685023498 BR00118047 KCNQ2 final crispr P13 U2OS 96 1110 Interphase +0.11582654493102254 0.0034847616327761213 BR00118046 CHRM3 final crispr B17 U2OS 96 468 Interphase 0.13234276166606992 1.348283850044456e-10 BR00118047 RGS4 final crispr N11 U2OS 96 1323 Large 0.16111346280837807 3.3299069157522762e-09 BR00118045 KCNJ1 final crispr F03 U2OS 96 770 Large 0.17907801418439717 2.5735929299034004e-08 BR00118045 FOXM1 final crispr A19 U2OS 96 564 Large @@ -989,6 +9809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.18245399425593023 2.2225731421150154e-07 BR00118046 HRH4 final crispr H24 U2OS 96 474 Large 0.2045551753635586 1.244501710205114e-06 BR00118045 RPL23A final crispr M18 U2OS 96 334 Large 0.12943410916726633 1.638224976839218e-06 BR00118045 ADH1C final crispr D02 U2OS 96 824 Large +0.10660316234956783 2.117996586860497e-06 BR00118045 PTGIR final crispr G08 U2OS 96 1204 Large +0.1108771340537817 4.863624004564899e-06 BR00118045 EZH2 final crispr C05 U2OS 96 1043 Large +0.2748632946001367 1.2958251394013024e-05 BR00118046 RPL23A final crispr M18 U2OS 96 152 Large +0.15825089217147761 1.3193381874905498e-05 BR00118045 TUBB3 final crispr K11 U2OS 96 471 Large +0.17472522965879264 1.3499456982124265e-05 BR00118048 TUBB3 final crispr K11 U2OS 96 384 Large +0.12805755395683452 2.1942884208168886e-05 BR00118046 TBXAS1 final crispr E24 U2OS 96 695 Large +0.14343729110812423 3.243873667361408e-05 BR00118045 AURKB final crispr C13 U2OS 96 526 Large +0.12160878402262283 3.2890115816505554e-05 BR00118046 ADH1C final crispr P04 U2OS 96 736 Large +0.09631258248016712 7.463247899998617e-05 BR00118047 GPR119 final crispr P21 U2OS 96 1094 Large +0.13392857142857142 8.501379323238266e-05 BR00118047 AURKB final crispr C13 U2OS 96 560 Large +0.15625628140703518 9.478335285892408e-05 BR00118045 RPL23A final crispr G14 U2OS 96 400 Large +0.116164568300473 0.00012120425540757267 BR00118045 IL1B final crispr H06 U2OS 96 709 Large +0.1215195139412937 0.0001287237122366271 BR00118048 CDK4 final crispr P03 U2OS 96 642 Large +0.1307235799807807 0.00013252824600455522 BR00118045 KCNMA1 final crispr A07 U2OS 96 554 Large +0.15387218045112783 0.00013465490381812934 BR00118047 FOXM1 final crispr A19 U2OS 96 399 Large +0.13004114168992462 0.00013948638004681108 BR00118045 KCNN4 final crispr A22 U2OS 96 557 Large +0.09731876861966236 0.00014274546878647275 BR00118047 SCNN1G final crispr P15 U2OS 96 1007 Large +0.13405660269394948 0.00017793958095026907 BR00118048 KCNQ2 final crispr A16 U2OS 96 513 Large +0.12665786783639352 0.00023314681677831628 BR00118048 PPAT final crispr E13 U2OS 96 554 Large +0.15223097112860892 0.0002861602513100138 BR00118047 HPGDS final crispr P14 U2OS 96 381 Large +0.14386792452830188 0.00030266788555402476 BR00118045 TUBB4B final crispr J13 U2OS 96 424 Large +0.14972004479283316 0.0003548966494001541 BR00118045 HCK final crispr H23 U2OS 96 376 Large +0.16557755775577557 0.00042726295730940056 BR00118047 TUBB3 final crispr K11 U2OS 96 303 Large +0.11956337563429142 0.0004304974002054768 BR00118046 S1PR1 final crispr P23 U2OS 96 579 Large +0.08515908704332763 0.0006242705607222097 BR00118045 CYP2A6 final crispr C07 U2OS 96 1102 Large +0.08688793561751819 0.0006576268979566412 BR00118047 PTK2B final crispr N15 U2OS 96 1044 Large +0.08347698379163368 0.0008249981891246999 BR00118046 CACNG1 final crispr L02 U2OS 96 1103 Large +0.09399805096850845 0.0009045239552558313 BR00118048 CYP2A6 final crispr C07 U2OS 96 866 Large +0.13102776683943337 0.0009621715196938597 BR00118046 AURKB final crispr C13 U2OS 96 434 Large +0.08995656998090412 0.0011184398863702228 BR00118045 LYN final crispr F22 U2OS 96 916 Large +0.10795266793598841 0.0012679281903735984 BR00118047 USP1 final crispr K18 U2OS 96 618 Large +0.091925820492875 0.0014245026314030657 BR00118046 ATP5F1D final crispr G21 U2OS 96 851 Large +0.11677012580030888 0.0016367028128368114 BR00118046 CACNA2D3 final crispr N24 U2OS 96 516 Large +0.08985680077988208 0.0017304236584537505 BR00118048 TGM2 final crispr O03 U2OS 96 859 Large +0.10134520276953511 0.0018467334783608832 BR00118048 FPR1 final crispr N22 U2OS 96 675 Large +0.1130701632026782 0.0018537265225591153 BR00118046 FOXM1 final crispr A19 U2OS 96 536 Large +0.1 0.0020024650342671314 BR00118047 PTPN2 final crispr A15 U2OS 96 690 Large +0.10756302521008404 0.0020326653054481576 BR00118047 CTSG final crispr G18 U2OS 96 595 Large +0.09430291801760074 0.002041768567632258 BR00118048 ATP5F1D final crispr E15 U2OS 96 765 Large +0.10863010581408579 0.002341770604000784 BR00118045 SCNN1G final crispr P15 U2OS 96 561 Large +0.09596662030598054 0.00264753270278796 BR00118046 TGFBR1 final crispr P24 U2OS 96 719 Large +0.1050258443755778 0.002686582284520115 BR00118046 ANXA1 final crispr F24 U2OS 96 586 Large +0.1241962951378028 0.0028978393889036486 BR00118048 FFAR2 final crispr A06 U2OS 96 414 Large +0.10164653013113305 0.0029386336239338594 BR00118047 PRKCE final crispr I17 U2OS 96 617 Large +0.0967176297831908 0.0029966682331225725 BR00118047 JAK1 final crispr M21 U2OS 96 680 Large +0.11366387045615792 0.003035362178630593 BR00118046 TUBB3 final crispr K11 U2OS 96 490 Large +0.09556762149771598 0.0030677023628986264 BR00118046 OPRM1 final crispr P22 U2OS 96 696 Large +0.1035044709283376 0.00308717552545417 BR00118045 KCNQ2 final crispr P13 U2OS 96 595 Large +0.0821134512627006 0.0031378646622564877 BR00118045 MET final crispr E20 U2OS 96 946 Large +0.08952274035150612 0.003157560709151095 BR00118045 FLT3 final crispr J20 U2OS 96 797 Large +0.17613861386138613 0.003191036285663819 BR00118048 PLK1 final crispr G09 U2OS 96 200 Large +0.14988442459029166 0.0032041899254297364 BR00118048 RPL23A final crispr G14 U2OS 96 278 Large +0.10383820108555182 0.003226208775648065 BR00118045 PARP3 final crispr L11 U2OS 96 583 Large +0.07441857885747062 0.0035842089681812563 BR00118045 CCR1 final crispr G02 U2OS 96 1124 Large +0.10881801125703565 0.0036070659230533495 BR00118047 KCNQ2 final crispr A16 U2OS 96 533 Large +0.11972716042752027 0.003645095546737933 BR00118047 JAK1 final crispr J09 U2OS 96 433 Large +0.09632708840857257 0.0037277704447595613 BR00118047 CDK2 final crispr F08 U2OS 96 662 Large +0.08351893095768374 0.003793081020436275 BR00118045 GABRB2 final crispr D10 U2OS 96 898 Large +0.09896585139350136 0.0037941102446815054 BR00118045 GUCY1B1 final crispr H21 U2OS 96 628 Large +0.11460061735833665 0.00398219184952495 BR00118048 AURKB final crispr C13 U2OS 96 466 Large +0.13450292397660818 0.004071842954307333 BR00118047 AKR1B1 final crispr H17 U2OS 96 342 Large +0.09595101405292515 0.004360377446695509 BR00118048 CYP1A2 final crispr K22 U2OS 96 657 Large +0.09879027986695198 0.00450015270335566 BR00118047 CACNG1 final crispr L02 U2OS 96 613 Large +0.10327148129952257 0.0045816226464648925 BR00118047 RNASE1 final crispr I13 U2OS 96 564 Large +0.07983193277310924 0.004620071450747049 BR00118048 DNMT3A final crispr L04 U2OS 96 952 Large +0.08931296092226837 0.0046711078241767675 BR00118045 HSP90AB1 final crispr B04 U2OS 96 752 Large +0.09030848689470673 0.00472452189511877 BR00118048 SLC29A1 final crispr N21 U2OS 96 726 Large +0.08921438082556592 0.005050959089148248 BR00118045 TGM2 final crispr B09 U2OS 96 751 Large +0.08454588824616853 0.005205463361053045 BR00118045 HTR3A final crispr O20 U2OS 96 820 Large +0.0988700406718132 0.005255146975801834 BR00118048 HIF1A final crispr M24 U2OS 96 599 Large +0.09787928221859707 0.00560434867419266 BR00118045 ITGB2 final crispr A17 U2OS 96 613 Large +0.08758169934640522 0.0056364367295128745 BR00118045 DCK final crispr I07 U2OS 96 765 Large +0.0843976279650437 0.006033323175243415 BR00118048 TGFBR1 final crispr P24 U2OS 96 800 Large +0.09906522642293311 0.006064670864976844 BR00118047 FGF1 final crispr I19 U2OS 96 581 Large +0.08420186462689404 0.006350044572759756 BR00118046 PAK1 final crispr N06 U2OS 96 797 Large +0.07771805659129603 0.006747564800437584 BR00118048 HBB final crispr M08 U2OS 96 923 Large +0.10367085934907852 0.00704102469190482 BR00118047 KCNMA1 final crispr A07 U2OS 96 516 Large +0.11576167586493383 0.007219907778331101 BR00118047 DYRK1B final crispr N16 U2OS 96 411 Large +0.07016055712290634 0.007274211249144375 BR00118045 PDE3A final crispr O08 U2OS 96 1131 Large +0.09459924320605435 0.007743312510257691 BR00118047 GRIN2A final crispr P09 U2OS 96 608 Large +0.07027027027027027 0.008312628421483961 BR00118047 KCNQ2 final crispr P13 U2OS 96 1110 Large +0.13978494623655913 0.008510069007360021 BR00118045 PLK1 final crispr G09 U2OS 96 279 Large +0.0901526647353658 0.008705976373034953 BR00118046 PDE7A final crispr C10 U2OS 96 660 Large +0.10241199530535174 0.009451883963451776 BR00118048 CDC25A final crispr D06 U2OS 96 502 Large +0.08296889436402834 0.009714292980595344 BR00118045 GPR55 final crispr H16 U2OS 96 764 Large +0.09121710994892249 0.009810234408499438 BR00118046 PLA2G1B final crispr L20 U2OS 96 626 Large +0.08665627731328024 0.010143759558012217 BR00118048 HCK final crispr M23 U2OS 96 697 Large +0.09253246753246754 0.01020927164659917 BR00118047 CYP3A4 final crispr D20 U2OS 96 616 Large +0.09562233175379502 0.010245538485323082 BR00118047 IMPDH1 final crispr G05 U2OS 96 561 Large +0.07989038239655906 0.01057193834358824 BR00118045 PDE3A final crispr P18 U2OS 96 809 Large 0.19464285714285715 1.0871980791644116e-09 BR00118047 AURKB final crispr C13 U2OS 96 560 Metaphase 0.20931556709698704 7.2480869487058364e-09 BR00118046 AURKB final crispr C13 U2OS 96 434 Metaphase 0.147394880208662 4.724235003547366e-07 BR00118046 SIRT2 final crispr P01 U2OS 96 689 Metaphase @@ -999,6 +9909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.12467906069269026 2.779073627969945e-05 BR00118045 SIRT2 final crispr P01 U2OS 96 709 Metaphase 0.11385002897248206 4.101113738048985e-05 BR00118048 SIRT2 final crispr P01 U2OS 96 824 Metaphase 0.1976361417747382 4.9679075170599376e-05 BR00118047 RPL23A final crispr M18 U2OS 96 262 Metaphase +0.16332322953981812 6.107221509442558e-05 BR00118048 RPL3 final crispr K04 U2OS 96 382 Metaphase +0.1783168316831683 0.00011055976778712196 BR00118047 TUBB3 final crispr K11 U2OS 96 303 Metaphase +0.12766438963962623 0.00013716803841879786 BR00118046 PPAT final crispr E13 U2OS 96 578 Metaphase +0.12245021059201797 0.00015731294258533888 BR00118047 USP1 final crispr K18 U2OS 96 618 Metaphase +0.11263736263736264 0.00019231700727676495 BR00118047 ALK final crispr G06 U2OS 96 728 Metaphase +0.17921146953405018 0.0002485875908180082 BR00118045 PLK1 final crispr G09 U2OS 96 279 Metaphase +0.22151067323481116 0.00026128190097784217 BR00118046 PLK1 final crispr G09 U2OS 96 175 Metaphase +0.12904756086165878 0.00026637194858716 BR00118045 AURKB final crispr C13 U2OS 96 526 Metaphase +0.10975609756097561 0.00027219944425089853 BR00118046 HSD11B1 final crispr O01 U2OS 96 738 Metaphase +0.09494630922880529 0.0002846497167351572 BR00118046 CDK4 final crispr P03 U2OS 96 966 Metaphase +0.099899177052486 0.0003034492038268799 BR00118047 CHEK2 final crispr K03 U2OS 96 868 Metaphase +0.10390270386293189 0.00033151377514975306 BR00118048 GJB4 final crispr H01 U2OS 96 794 Metaphase +0.10881877022653721 0.0003664293913127957 BR00118046 HIF1A final crispr A01 U2OS 96 721 Metaphase +0.11160058737151249 0.00040976430034338397 BR00118047 MAPK14 final crispr M17 U2OS 96 681 Metaphase +0.11247659360198896 0.0007362137762333785 BR00118047 UGT1A9 final crispr J01 U2OS 96 618 Metaphase +0.08564043102403482 0.0008186757262901319 BR00118045 RNASE1 final crispr K09 U2OS 96 1054 Metaphase +0.09878040335425313 0.0008387661459697402 BR00118048 KCNN4 final crispr K01 U2OS 96 787 Metaphase +0.09346476570964611 0.0009323841723798988 BR00118047 GPR119 final crispr G23 U2OS 96 863 Metaphase +0.12219439923208547 0.0011192549626487535 BR00118046 TUBB3 final crispr K11 U2OS 96 490 Metaphase +0.10201766069754822 0.001266258882796961 BR00118047 TGFBR1 final crispr P24 U2OS 96 696 Metaphase +0.09281542655476882 0.0015390907490608573 BR00118047 PPARD final crispr N03 U2OS 96 819 Metaphase +0.17398119122257052 0.0016288440416607605 BR00118048 RPL23A final crispr M18 U2OS 96 231 Metaphase +0.20088394639292842 0.0016953417520356665 BR00118046 PLK1 final crispr F13 U2OS 96 168 Metaphase +0.09421095219989666 0.001716369645780844 BR00118045 BRD4 final crispr M19 U2OS 96 786 Metaphase +0.11170212765957446 0.001742349910439026 BR00118045 FOXM1 final crispr A19 U2OS 96 564 Metaphase +0.12023761123910195 0.0019011897543365242 BR00118045 TUBB3 final crispr K11 U2OS 96 471 Metaphase +0.09424477331454076 0.0019075359921171835 BR00118046 SLC7A11 final crispr A05 U2OS 96 774 Metaphase +0.08635922789421394 0.0019811949630634427 BR00118046 CYP2A6 final crispr C07 U2OS 96 920 Metaphase +0.083830352733967 0.0024596761168479303 BR00118045 ICAM1 final crispr C20 U2OS 96 938 Metaphase +0.10372771474878444 0.002600694589859621 BR00118046 PTPN2 final crispr A15 U2OS 96 617 Metaphase +0.14317956962651496 0.002765820572246773 BR00118048 FOXM1 final crispr A19 U2OS 96 312 Metaphase +0.08605582922824302 0.0028643481113452838 BR00118047 RET final crispr I03 U2OS 96 870 Metaphase +0.10368674043170688 0.003030107858130304 BR00118046 OPRL1 final crispr A11 U2OS 96 596 Metaphase +0.09968360591900312 0.003120211109558295 BR00118045 NAMPT final crispr D18 U2OS 96 640 Metaphase +0.09457579972183588 0.003204693957659012 BR00118046 TGFBR1 final crispr P24 U2OS 96 719 Metaphase +0.08769458814636336 0.0032248987527556732 BR00118046 SLCO2B1 final crispr I24 U2OS 96 822 Metaphase +0.08741428887414289 0.0033844736177459497 BR00118048 MAPK8 final crispr D07 U2OS 96 825 Metaphase +0.22816091954022988 0.003396317787583978 BR00118047 PLK1 final crispr F13 U2OS 96 116 Metaphase +0.08748481166464156 0.0036611466523587435 BR00118047 KCNK1 final crispr C17 U2OS 96 823 Metaphase +0.08958060288335518 0.004046956075417056 BR00118045 CLK1 final crispr N05 U2OS 96 760 Metaphase +0.09078771695594126 0.0041494060583097125 BR00118048 ABL1 final crispr C01 U2OS 96 749 Metaphase +0.09476739149267954 0.0041981014376198935 BR00118047 GAA final crispr L18 U2OS 96 679 Metaphase +0.08936871387333739 0.004207934473791318 BR00118046 SLC7A11 final crispr P05 U2OS 96 756 Metaphase +0.1017099750506049 0.004269686523903483 BR00118047 PDE7A final crispr C10 U2OS 96 584 Metaphase +0.0913372817836992 0.004415561296416591 BR00118048 F10 final crispr H07 U2OS 96 726 Metaphase +0.09077481868024505 0.0046178186575722546 BR00118046 CACNB4 final crispr B01 U2OS 96 722 Metaphase +0.10681904594776404 0.004639935244028295 BR00118046 ABL1 final crispr P20 U2OS 96 522 Metaphase +0.08312655753200997 0.004776651707565527 BR00118046 LPAR1 final crispr L01 U2OS 96 864 Metaphase +0.07587976539589443 0.004936023558448478 BR00118045 PPAT final crispr G13 U2OS 96 1023 Metaphase +0.08963084617968721 0.005099505869512567 BR00118047 PTGIS final crispr K17 U2OS 96 734 Metaphase +0.09035807099173682 0.005291333404676175 BR00118046 ABL1 final crispr C01 U2OS 96 718 Metaphase +0.10572473802466592 0.005820031084373397 BR00118048 KCNQ2 final crispr A16 U2OS 96 513 Metaphase +0.0816386614770858 0.005941251425390305 BR00118045 TNF final crispr I10 U2OS 96 859 Metaphase +0.1834319526627219 0.006680982573926605 BR00118047 PLK1 final crispr G09 U2OS 96 169 Metaphase +0.09151306699591381 0.006954499075613754 BR00118048 ELANE final crispr N19 U2OS 96 667 Metaphase +0.11845613495359689 0.007037463232113649 BR00118047 MAPK8 final crispr D13 U2OS 96 394 Metaphase +0.0827250608272506 0.007189320544525277 BR00118047 CYP2A6 final crispr C07 U2OS 96 822 Metaphase +0.1041531573259225 0.007194471916279991 BR00118048 AGER final crispr K20 U2OS 96 510 Metaphase +0.09766378615869845 0.007229554997729766 BR00118046 S1PR1 final crispr P23 U2OS 96 579 Metaphase +0.09186746987951808 0.0073398111285180815 BR00118047 GJB4 final crispr H01 U2OS 96 664 Metaphase +0.08852182588763008 0.00750856064345462 BR00118048 HCK final crispr M23 U2OS 96 697 Metaphase +0.11940206692913385 0.0076074012720371426 BR00118048 TUBB3 final crispr K11 U2OS 96 384 Metaphase +0.0988039892995351 0.008103257199490583 BR00118045 KCNMA1 final crispr A07 U2OS 96 554 Metaphase +0.08369622924269 0.00811546010082749 BR00118047 CA14 final crispr C19 U2OS 96 772 Metaphase +0.09127774305606023 0.008322146943284052 BR00118047 TNF final crispr I10 U2OS 96 643 Metaphase +0.08931539905264099 0.008876173562612697 BR00118046 P2RY12 final crispr P19 U2OS 96 670 Metaphase +0.0807809063312308 0.008909129975006331 BR00118045 HDAC6 final crispr K12 U2OS 96 812 Metaphase +0.08513513513513514 0.00934205665177257 BR00118048 PTGIS final crispr I16 U2OS 96 740 Metaphase +0.09278047738559299 0.009388917302540958 BR00118047 PAK1 final crispr K10 U2OS 96 610 Metaphase +0.07771459092622848 0.009436418904431402 BR00118048 IL1B final crispr H06 U2OS 96 876 Metaphase +0.096835526379178 0.009672360084629864 BR00118045 KCNN4 final crispr A22 U2OS 96 557 Metaphase +0.08276367524315376 0.009988461617795725 BR00118047 MMP2 final crispr E07 U2OS 96 760 Metaphase +0.08615819209039548 0.010406749738090283 BR00118047 ERBB2 final crispr H12 U2OS 96 708 Metaphase +0.07745580019361922 0.010632427754696968 BR00118045 AKR1B1 final crispr L21 U2OS 96 858 Metaphase +0.09155580192165558 0.010858197306980852 BR00118047 PAK4 final crispr M16 U2OS 96 615 Metaphase +0.08224543080939947 0.011211891458461827 BR00118046 P3H1 final crispr I01 U2OS 96 766 Metaphase +0.09933576237386232 0.011552643987860007 BR00118046 ITGB2 final crispr A17 U2OS 96 516 Metaphase +0.07391862705037651 0.012055209823236344 BR00118046 NTRK1 final crispr P07 U2OS 96 926 Metaphase +0.09061029457214344 0.012098573884395617 BR00118045 BRD4 final crispr J16 U2OS 96 611 Metaphase +0.0814073502629623 0.012909021497570883 BR00118047 SIRT2 final crispr O19 U2OS 96 753 Metaphase +0.13066813374900665 0.013155979267721158 BR00118046 HPGDS final crispr B19 U2OS 96 287 Metaphase +0.13218464374407948 0.013287193816452174 BR00118046 RPL23A final crispr G14 U2OS 96 278 Metaphase +0.07444444444444444 0.01361653385581104 BR00118048 BRAF final crispr J10 U2OS 96 900 Metaphase +0.09338996616698395 0.013667771594925621 BR00118046 DDR2 final crispr A03 U2OS 96 561 Metaphase +0.09380530973451327 0.013822810951438337 BR00118047 DDR2 final crispr A03 U2OS 96 565 Metaphase +0.08621381081366307 0.014319060727723378 BR00118048 CA5A final crispr M01 U2OS 96 655 Metaphase +0.07612239635561413 0.014328652730127225 BR00118045 JAK1 final crispr M21 U2OS 96 836 Metaphase +0.08633781116086475 0.01455699641963944 BR00118046 PIK3CG final crispr I08 U2OS 96 645 Metaphase +0.09098598995506212 0.014567411390879881 BR00118048 GHSR final crispr A09 U2OS 96 585 Metaphase +0.0817174515235457 0.01607942545802141 BR00118047 IGF1R final crispr E19 U2OS 96 722 Metaphase 0.13866231647634583 1.4790714479886962e-05 BR00118045 ITGB2 final crispr A17 U2OS 96 613 MetaphaseAlignment 0.17404129793510326 6.68938809852398e-05 BR00118045 CHRM3 final crispr B21 U2OS 96 339 MetaphaseAlignment 0.1969111969111969 8.309693501313532e-05 BR00118045 FFAR2 final crispr A24 U2OS 96 259 MetaphaseAlignment @@ -1009,6 +10009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.12562814070351758 0.00015910352571954321 BR00118047 GRIN2A final crispr A23 U2OS 96 597 MetaphaseAlignment 0.09169200180332228 0.000173350569287066 BR00118045 CYP2A6 final crispr C07 U2OS 96 1102 MetaphaseAlignment 0.11395589758768684 0.00020607637554089512 BR00118047 TGFBR1 final crispr P24 U2OS 96 696 MetaphaseAlignment +0.12122678018575851 0.00022418568326476802 BR00118047 GRIN2A final crispr P09 U2OS 96 608 MetaphaseAlignment +0.11622774203202155 0.0002568961870513003 BR00118045 TGFBR1 final crispr P24 U2OS 96 656 MetaphaseAlignment +0.11993517017828201 0.00027569489461140584 BR00118046 BRD4 final crispr J16 U2OS 96 617 MetaphaseAlignment +0.12305251426791237 0.0003830876301878967 BR00118045 KCNN4 final crispr A22 U2OS 96 557 MetaphaseAlignment +0.10938974409531992 0.00038629781388718884 BR00118047 SIRT2 final crispr P01 U2OS 96 703 MetaphaseAlignment +0.12089810017271158 0.0004167185459095201 BR00118048 PLA2G1B final crispr L20 U2OS 96 579 MetaphaseAlignment +0.10848400556328233 0.00041827779317550547 BR00118046 TGFBR1 final crispr P24 U2OS 96 719 MetaphaseAlignment +0.10139244407267879 0.0004928259384271564 BR00118048 TUBB4B final crispr C04 U2OS 96 796 MetaphaseAlignment +0.1138034960819771 0.0005111608204470218 BR00118045 SLCO2B1 final crispr A21 U2OS 96 630 MetaphaseAlignment +0.10269041303524062 0.0006269098323917312 BR00118046 HBB final crispr F21 U2OS 96 754 MetaphaseAlignment +0.1215291052489982 0.0006553990375407105 BR00118046 DHH final crispr F05 U2OS 96 531 MetaphaseAlignment +0.10986793032337326 0.0007829007875269061 BR00118047 S1PR2 final crispr K02 U2OS 96 642 MetaphaseAlignment +0.09406651002102914 0.000905882487319892 BR00118045 GHSR final crispr A09 U2OS 96 863 MetaphaseAlignment +0.16136216592843278 0.0009599150420709901 BR00118045 KCNN1 final crispr B24 U2OS 96 284 MetaphaseAlignment +0.11258797935417822 0.0009654515579280574 BR00118048 BRD4 final crispr J16 U2OS 96 595 MetaphaseAlignment +0.10785824345146379 0.0010428588139448345 BR00118048 HSP90AA1 final crispr C03 U2OS 96 649 MetaphaseAlignment +0.1197056568361543 0.0011218236884506815 BR00118048 KCNQ2 final crispr A16 U2OS 96 513 MetaphaseAlignment +0.10445924294907942 0.0011713626134681177 BR00118046 PTGIS final crispr I16 U2OS 96 669 MetaphaseAlignment +0.12224158565519558 0.0011985935912948735 BR00118048 FGF1 final crispr J12 U2OS 96 485 MetaphaseAlignment +0.08108108108108109 0.0013483551118301928 BR00118047 KCNQ2 final crispr P13 U2OS 96 1110 MetaphaseAlignment +0.1484848484848485 0.0013624798047529667 BR00118047 KCNN4 final crispr A22 U2OS 96 330 MetaphaseAlignment +0.09562721436372838 0.0014987229554592326 BR00118045 GRIN2A final crispr A23 U2OS 96 774 MetaphaseAlignment +0.1331974568015177 0.0015941437193006875 BR00118047 MAPK8 final crispr D13 U2OS 96 394 MetaphaseAlignment +0.10906040268456375 0.0016550571664600661 BR00118047 ITGB2 final crispr A17 U2OS 96 596 MetaphaseAlignment +0.09453835032241202 0.0017408851142406193 BR00118045 TUBB4B final crispr C04 U2OS 96 777 MetaphaseAlignment +0.09751142712036567 0.0019159017093866467 BR00118046 PTGIR final crispr G10 U2OS 96 716 MetaphaseAlignment +0.0992041551478596 0.002017083581086534 BR00118046 ELANE final crispr N19 U2OS 96 690 MetaphaseAlignment +0.10567471692311071 0.0020179803088078065 BR00118046 GJB4 final crispr H01 U2OS 96 604 MetaphaseAlignment +0.16279069767441862 0.0021097751546781313 BR00118045 PLK1 final crispr F13 U2OS 96 258 MetaphaseAlignment +0.09966087769746444 0.0022449022320812947 BR00118048 CDK2 final crispr L19 U2OS 96 676 MetaphaseAlignment +0.09426420380577283 0.0024736081334845172 BR00118048 OPRM1 final crispr C23 U2OS 96 738 MetaphaseAlignment +0.11259541984732824 0.002585812288010156 BR00118046 TNF final crispr N17 U2OS 96 524 MetaphaseAlignment +0.10592312761850962 0.0026287485019396823 BR00118048 FLT3 final crispr G16 U2OS 96 584 MetaphaseAlignment +0.10815602836879433 0.0027083547459243146 BR00118045 FOXM1 final crispr A19 U2OS 96 564 MetaphaseAlignment +0.08904824378317133 0.00277603135383503 BR00118048 BRD4 final crispr M19 U2OS 96 820 MetaphaseAlignment +0.07636513562290193 0.00314420024152123 BR00118047 GPR119 final crispr P21 U2OS 96 1094 MetaphaseAlignment +0.09544159544159544 0.0033239209605512533 BR00118046 RET final crispr I03 U2OS 96 702 MetaphaseAlignment +0.08487676921950352 0.00337068935466612 BR00118048 HTR3A final crispr O02 U2OS 96 877 MetaphaseAlignment +0.11843001677767044 0.0035199464043105017 BR00118046 KCNMA1 final crispr A07 U2OS 96 445 MetaphaseAlignment +0.10850080501408775 0.003761348378799222 BR00118046 BAX final crispr L14 U2OS 96 527 MetaphaseAlignment +0.1056231918997107 0.004041237113100733 BR00118048 CA14 final crispr G15 U2OS 96 544 MetaphaseAlignment +0.10760888351192534 0.004064162235837038 BR00118046 FLT3 final crispr G16 U2OS 96 526 MetaphaseAlignment +0.10450484377840688 0.004192346368962166 BR00118045 KCNMA1 final crispr A07 U2OS 96 554 MetaphaseAlignment +0.09518554283349427 0.004413470082823041 BR00118046 PDE7A final crispr C10 U2OS 96 660 MetaphaseAlignment +0.10443788171006108 0.0046383034775988345 BR00118048 DYRK1B final crispr N16 U2OS 96 544 MetaphaseAlignment +0.08033958274799637 0.00481578390559464 BR00118045 LYN final crispr F22 U2OS 96 916 MetaphaseAlignment +0.09553158705701079 0.005330705652022391 BR00118045 LCK final crispr O15 U2OS 96 649 MetaphaseAlignment +0.09413855599421161 0.005523000649369191 BR00118047 NTRK1 final crispr P07 U2OS 96 654 MetaphaseAlignment +0.08691227565222755 0.005711323596152023 BR00118048 CACNB4 final crispr I23 U2OS 96 766 MetaphaseAlignment +0.109892939422686 0.005772206049991681 BR00118045 HRH4 final crispr H24 U2OS 96 471 MetaphaseAlignment +0.08082579529585045 0.005913546552069569 BR00118048 ATM final crispr F14 U2OS 96 881 MetaphaseAlignment +0.10509577970667465 0.005962197666455981 BR00118048 PIK3CG final crispr I08 U2OS 96 520 MetaphaseAlignment +0.07817683873873046 0.00619190961499734 BR00118048 PORCN final crispr N07 U2OS 96 934 MetaphaseAlignment +0.12231243001119821 0.006194569725424503 BR00118045 HCK final crispr H23 U2OS 96 376 MetaphaseAlignment +0.1024306039893988 0.006324376815883655 BR00118046 FOXM1 final crispr A19 U2OS 96 536 MetaphaseAlignment +0.08575004053177691 0.0064003265583234105 BR00118046 TGM2 final crispr B09 U2OS 96 771 MetaphaseAlignment +0.07547169811320754 0.006439500010018227 BR00118047 SCNN1G final crispr P15 U2OS 96 1007 MetaphaseAlignment +0.08098591549295775 0.0074636057782767945 BR00118046 TGM2 final crispr O03 U2OS 96 852 MetaphaseAlignment +0.09340632953945156 0.0075295900338966226 BR00118045 KCNQ2 final crispr A16 U2OS 96 627 MetaphaseAlignment +0.08985507246376812 0.007586863915737646 BR00118047 PTPN2 final crispr A15 U2OS 96 690 MetaphaseAlignment +0.10371313879882661 0.0076300110309880775 BR00118048 AGER final crispr K20 U2OS 96 510 MetaphaseAlignment +0.11188991874745742 0.008116838031232807 BR00118045 FOXM1 final crispr F23 U2OS 96 426 MetaphaseAlignment +0.09322049685308637 0.008853234283036871 BR00118047 HTR3A final crispr O02 U2OS 96 611 MetaphaseAlignment +0.07739941598209314 0.008994363428976896 BR00118045 CYP1A2 final crispr K22 U2OS 96 889 MetaphaseAlignment +0.08760032365536197 0.009240495572504375 BR00118048 MME final crispr G17 U2OS 96 687 MetaphaseAlignment +0.09089077135500243 0.009753417812911263 BR00118047 MMP2 final crispr D14 U2OS 96 635 MetaphaseAlignment +0.10116940827941062 0.010102570869813005 BR00118046 GRIN2A final crispr P09 U2OS 96 508 MetaphaseAlignment +0.11577306859351914 0.010221757417346707 BR00118045 CCND1 final crispr B23 U2OS 96 383 MetaphaseAlignment +0.12377031650983747 0.010379253554660366 BR00118045 RPL23A final crispr M18 U2OS 96 334 MetaphaseAlignment +0.08549892519518296 0.01045273809614588 BR00118047 OPRL1 final crispr A11 U2OS 96 707 MetaphaseAlignment +0.08820384189873037 0.010928954280772113 BR00118045 MAPK8 final crispr D13 U2OS 96 659 MetaphaseAlignment +0.08071519795657726 0.011069001322082784 BR00118048 KCNMA1 final crispr E23 U2OS 96 783 MetaphaseAlignment +0.07643688995014872 0.011225246265786243 BR00118048 IL1B final crispr H06 U2OS 96 876 MetaphaseAlignment +0.09149050905953408 0.011242067701334272 BR00118046 DDR2 final crispr B03 U2OS 96 608 MetaphaseAlignment +0.09020314393164545 0.011527425977732837 BR00118047 UGT1A9 final crispr J01 U2OS 96 618 MetaphaseAlignment +0.08496139788040384 0.011711156146896511 BR00118046 GJB4 final crispr N01 U2OS 96 699 MetaphaseAlignment +0.09902463526906871 0.011736474042672453 BR00118046 ITGB2 final crispr A17 U2OS 96 516 MetaphaseAlignment +0.09744692689607944 0.011901876489716384 BR00118045 MAPK14 final crispr A20 U2OS 96 528 MetaphaseAlignment +0.07665711772026952 0.011904709043687697 BR00118045 SLC7A11 final crispr A05 U2OS 96 863 MetaphaseAlignment +0.09126744634924777 0.012086539592117668 BR00118046 KCNJ1 final crispr F03 U2OS 96 606 MetaphaseAlignment +0.07719298245614035 0.012232308751059448 BR00118046 SSTR2 final crispr C02 U2OS 96 855 MetaphaseAlignment +0.07837111196934138 0.012382260589062243 BR00118048 GPR119 final crispr P21 U2OS 96 821 MetaphaseAlignment +0.09209274184073873 0.012391224058049955 BR00118045 PARP3 final crispr L11 U2OS 96 583 MetaphaseAlignment +0.07910341892467017 0.012654125832036305 BR00118046 GPR119 final crispr G23 U2OS 96 795 MetaphaseAlignment +0.09765857591413915 0.012743107107591347 BR00118048 TNF final crispr N17 U2OS 96 523 MetaphaseAlignment +0.07553854309010657 0.013359124336176857 BR00118048 KDR final crispr O18 U2OS 96 867 MetaphaseAlignment +0.0868454481298518 0.013423223584038716 BR00118048 CDK9 final crispr I20 U2OS 96 654 MetaphaseAlignment +0.09335533052679486 0.013537609804142089 BR00118045 SCNN1G final crispr P15 U2OS 96 561 MetaphaseAlignment +0.07732147497224387 0.013567809598228248 BR00118046 MAPK14 final crispr M17 U2OS 96 822 MetaphaseAlignment +0.08956515006287663 0.013584594759265014 BR00118048 ERBB2 final crispr H12 U2OS 96 613 MetaphaseAlignment 0.1879432624113475 4.028624763521718e-09 BR00118045 FOXM1 final crispr A19 U2OS 96 564 OutOfFocus 0.14821280414500754 7.532559360078483e-08 BR00118045 KCNJ1 final crispr F03 U2OS 96 770 OutOfFocus 0.15397702780543443 9.26595666370037e-06 BR00118048 KCNQ2 final crispr A16 U2OS 96 513 OutOfFocus @@ -1019,6 +10109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.10817802883996396 7.589751141934372e-05 BR00118045 SLC7A11 final crispr A05 U2OS 96 863 OutOfFocus 0.13397614730087878 0.00010718721056473559 BR00118046 FOXM1 final crispr A19 U2OS 96 536 OutOfFocus 0.10478359908883828 0.00012855618090232526 BR00118045 KDR final crispr J02 U2OS 96 878 OutOfFocus +0.17259254678868827 0.00014002344503074806 BR00118048 FOXM1 final crispr A19 U2OS 96 312 OutOfFocus +0.0822333611807296 0.00023330409268598607 BR00118047 RGS4 final crispr N11 U2OS 96 1323 OutOfFocus +0.1106025581753737 0.0002478394089262908 BR00118046 HIF1A final crispr A01 U2OS 96 721 OutOfFocus +0.09653555109639049 0.0003064080789491053 BR00118047 EDNRB final crispr K06 U2OS 96 931 OutOfFocus +0.10811756215388241 0.0003298098438067121 BR00118046 ADH1C final crispr P04 U2OS 96 736 OutOfFocus +0.11908646003262642 0.00033090087390128783 BR00118045 ITGB2 final crispr A17 U2OS 96 613 OutOfFocus +0.10648341746349742 0.00033717750179491847 BR00118047 GLRA3 final crispr E21 U2OS 96 755 OutOfFocus +0.13812090091006152 0.00036570729800754963 BR00118046 KCNMA1 final crispr A07 U2OS 96 445 OutOfFocus +0.11143270622286541 0.00037119877698665844 BR00118047 FFAR4 final crispr E04 U2OS 96 691 OutOfFocus +0.13793488787901365 0.00042342139729220716 BR00118046 AURKB final crispr C13 U2OS 96 434 OutOfFocus +0.08337836533822253 0.00043414829120280723 BR00118045 PTGIR final crispr G08 U2OS 96 1204 OutOfFocus +0.1144328345373237 0.0006010224716575135 BR00118047 GRIN2A final crispr P09 U2OS 96 608 OutOfFocus +0.14361662652390686 0.0006108373879948837 BR00118045 CCND1 final crispr B23 U2OS 96 383 OutOfFocus +0.10157053285216024 0.0006586039409348281 BR00118047 CA14 final crispr C19 U2OS 96 772 OutOfFocus +0.11780783201600704 0.0007818908066207677 BR00118045 KCNN4 final crispr A22 U2OS 96 557 OutOfFocus +0.1211503027112398 0.0007985308857100054 BR00118046 ABL1 final crispr P20 U2OS 96 522 OutOfFocus +0.11686009026434559 0.0008132845959424225 BR00118045 SCNN1G final crispr P15 U2OS 96 561 OutOfFocus +0.08771882550546559 0.0008240605221900887 BR00118048 LPAR1 final crispr L01 U2OS 96 999 OutOfFocus +0.10119840213049268 0.0009064557611210376 BR00118045 TGM2 final crispr B09 U2OS 96 751 OutOfFocus +0.08461683419972514 0.0010474128843064607 BR00118045 P2RY12 final crispr O21 U2OS 96 1045 OutOfFocus +0.10164835164835165 0.0010736971254303774 BR00118047 ALK final crispr G06 U2OS 96 728 OutOfFocus +0.11021069692058347 0.0011023413557094217 BR00118046 BRD4 final crispr J16 U2OS 96 617 OutOfFocus +0.11942358157632793 0.001136675202532842 BR00118047 KCNMA1 final crispr A07 U2OS 96 516 OutOfFocus +0.09204038836698093 0.0013740155721524965 BR00118047 PRKCE final crispr K05 U2OS 96 843 OutOfFocus +0.10013908205841446 0.0014678910257908291 BR00118046 TGFBR1 final crispr P24 U2OS 96 719 OutOfFocus +0.10128388017118402 0.0014956404169947978 BR00118045 CACNA2D3 final crispr N24 U2OS 96 701 OutOfFocus +0.09465615404500545 0.001495653961870455 BR00118045 SLC7A11 final crispr P05 U2OS 96 796 OutOfFocus +0.08908685968819599 0.0015975625715947976 BR00118045 GABRB2 final crispr D10 U2OS 96 898 OutOfFocus +0.08101488649965426 0.0016778517131484094 BR00118045 HSD11B1 final crispr O23 U2OS 96 1067 OutOfFocus +0.09556752533870604 0.0016898369563209778 BR00118048 CACNB4 final crispr I23 U2OS 96 766 OutOfFocus +0.12059887246037655 0.0017243280311958662 BR00118046 HRH4 final crispr H24 U2OS 96 474 OutOfFocus +0.09530026109660575 0.0018926428005091906 BR00118045 PDE7A final crispr C22 U2OS 96 766 OutOfFocus +0.10211523428518876 0.0019447875754864564 BR00118046 PDE7A final crispr C10 U2OS 96 660 OutOfFocus +0.11016024725346077 0.002092751521375839 BR00118045 KCNMA1 final crispr A07 U2OS 96 554 OutOfFocus +0.10450137160181062 0.002093861569085003 BR00118047 UGT1A9 final crispr J01 U2OS 96 618 OutOfFocus +0.07728783746207896 0.002177042194110805 BR00118045 PDE3A final crispr O08 U2OS 96 1131 OutOfFocus +0.18123762376237623 0.0021981073709605565 BR00118048 PLK1 final crispr G09 U2OS 96 200 OutOfFocus +0.11275292669704473 0.0023195972192205975 BR00118045 ADORA2A final crispr B22 U2OS 96 521 OutOfFocus +0.09674163064100083 0.002393595699557707 BR00118045 SIRT2 final crispr P01 U2OS 96 709 OutOfFocus +0.07693541752365282 0.0027099975931413867 BR00118045 BAX final crispr E06 U2OS 96 1105 OutOfFocus +0.08598563702363143 0.002851037036593454 BR00118048 HTR3A final crispr O02 U2OS 96 877 OutOfFocus +0.09710144927536232 0.0029730176722658173 BR00118047 PTPN2 final crispr A15 U2OS 96 690 OutOfFocus +0.09593193243726468 0.003261637974064476 BR00118046 SIRT2 final crispr P01 U2OS 96 689 OutOfFocus +0.10619469026548672 0.0033968825316020423 BR00118047 DDR2 final crispr A03 U2OS 96 565 OutOfFocus +0.08829948145143285 0.003736796072895289 BR00118045 FLT3 final crispr J20 U2OS 96 797 OutOfFocus +0.08685669986284215 0.0037617326779395663 BR00118045 HTR3A final crispr O20 U2OS 96 820 OutOfFocus +0.09846513278523689 0.003809487344654303 BR00118046 IL1B final crispr H06 U2OS 96 636 OutOfFocus +0.13033935761208487 0.003826205700519236 BR00118045 BTK final crispr D24 U2OS 96 363 OutOfFocus +0.08142924896774914 0.0039017284645959487 BR00118045 CA5A final crispr I02 U2OS 96 928 OutOfFocus +0.10217755443886097 0.0039056542840131972 BR00118047 GRIN2A final crispr A23 U2OS 96 597 OutOfFocus +0.10744853111265325 0.00413353164617666 BR00118048 IL1B final crispr H18 U2OS 96 528 OutOfFocus +0.13471573743477067 0.004288674552928404 BR00118047 BTK final crispr D24 U2OS 96 331 OutOfFocus +0.0875 0.004357523572121817 BR00118045 CA14 final crispr C19 U2OS 96 800 OutOfFocus +0.08551321462405506 0.0045277177111061025 BR00118047 PPARD final crispr N03 U2OS 96 819 OutOfFocus +0.10011924636298593 0.004544360171533686 BR00118046 CACNB4 final crispr I23 U2OS 96 599 OutOfFocus +0.10687022900763359 0.005005137482130151 BR00118046 KCNN4 final crispr A22 U2OS 96 524 OutOfFocus +0.08984205404596153 0.0050491089080638586 BR00118047 CHRM2 final crispr B07 U2OS 96 732 OutOfFocus +0.08819277784795027 0.005176093581627917 BR00118046 KCNMA1 final crispr E23 U2OS 96 754 OutOfFocus +0.09512266355140186 0.005509876285911155 BR00118045 NAMPT final crispr D18 U2OS 96 640 OutOfFocus +0.12302634334296604 0.005591554904381778 BR00118048 TUBB final crispr J17 U2OS 96 379 OutOfFocus +0.0875888366451379 0.005682291828814458 BR00118046 PRKCE final crispr I17 U2OS 96 757 OutOfFocus +0.08355013421945769 0.005906363716551957 BR00118048 SIRT2 final crispr P01 U2OS 96 824 OutOfFocus +0.08167512539536341 0.00591068851756001 BR00118045 TNF final crispr I10 U2OS 96 859 OutOfFocus +0.07957121374652856 0.006258549778116484 BR00118048 HSD11B1 final crispr O23 U2OS 96 898 OutOfFocus +0.10119442601194426 0.0065495872699796774 BR00118046 CHEK2 final crispr M07 U2OS 96 550 OutOfFocus +0.10318949343339587 0.006825832477860164 BR00118047 KCNQ2 final crispr A16 U2OS 96 533 OutOfFocus +0.08250978443569264 0.00731364670692735 BR00118047 GABRB2 final crispr D10 U2OS 96 807 OutOfFocus +0.07000503861352567 0.007354234785877893 BR00118045 CCR1 final crispr G02 U2OS 96 1124 OutOfFocus +0.08457968547341116 0.007465223374453673 BR00118046 TGM2 final crispr B09 U2OS 96 771 OutOfFocus +0.14671814671814673 0.007510504221355728 BR00118045 FFAR2 final crispr A24 U2OS 96 259 OutOfFocus +0.11722555504281393 0.007694545931909507 BR00118047 MAPK8 final crispr D13 U2OS 96 394 OutOfFocus +0.08368317311017359 0.008654779788913583 BR00118046 KCNJ1 final crispr E14 U2OS 96 760 OutOfFocus +0.09075263076555629 0.00873089165879514 BR00118047 NTRK1 final crispr P07 U2OS 96 654 OutOfFocus +0.0824649784826776 0.008770766610542255 BR00118047 HTR2C final crispr L03 U2OS 96 792 OutOfFocus +0.11424224862358737 0.00877442132155367 BR00118047 ANXA1 final crispr F24 U2OS 96 408 OutOfFocus +0.10597197164361344 0.008933460375419847 BR00118046 CHRM3 final crispr B17 U2OS 96 468 OutOfFocus +0.07388663967611336 0.009070210703966956 BR00118046 S100B final crispr D22 U2OS 96 988 OutOfFocus +0.08602455146364495 0.00952706517457479 BR00118046 MAPK8 final crispr D07 U2OS 96 706 OutOfFocus +0.08152669793741567 0.00964738263717874 BR00118045 GAA final crispr L17 U2OS 96 790 OutOfFocus +0.08274125681175415 0.010019949358145909 BR00118047 MMP2 final crispr E07 U2OS 96 760 OutOfFocus +0.10822955583229556 0.010478431599585364 BR00118047 CSK final crispr B11 U2OS 96 438 OutOfFocus +0.08858858858858859 0.010710825975134017 BR00118047 TNNC1 final crispr L09 U2OS 96 666 OutOfFocus +0.07670918687947718 0.01082236552073184 BR00118048 IL1B final crispr H06 U2OS 96 876 OutOfFocus +0.09642857142857143 0.010917071303304753 BR00118047 AURKB final crispr C13 U2OS 96 560 OutOfFocus +0.07717726975267579 0.011040416368047801 BR00118045 AKR1B1 final crispr L21 U2OS 96 858 OutOfFocus +0.07080985001221897 0.011073434086994176 BR00118045 PPAT final crispr G13 U2OS 96 1023 OutOfFocus +0.09923664122137404 0.011439118168324828 BR00118046 TNF final crispr N17 U2OS 96 524 OutOfFocus +0.08687006192611574 0.01161258308306118 BR00118046 CA5A final crispr M01 U2OS 96 672 OutOfFocus +0.08020050125313283 0.011772644521187136 BR00118045 NTRK1 final crispr P07 U2OS 96 798 OutOfFocus +0.07305757596356469 0.012015722671550195 BR00118047 RNASE1 final crispr K09 U2OS 96 939 OutOfFocus 0.21964285714285714 3.0382399992700597e-12 BR00118047 AURKB final crispr C13 U2OS 96 560 Polylobed 0.2414991326188525 1.1258012465961065e-11 BR00118046 AURKB final crispr C13 U2OS 96 434 Polylobed 0.1647595362510512 9.635337243624402e-07 BR00118045 AURKB final crispr C13 U2OS 96 526 Polylobed @@ -1029,6 +10209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.1288620378035756 1.855548308604213e-05 BR00118045 PPAT final crispr E13 U2OS 96 687 Polylobed 0.1657693688150541 3.140066122861143e-05 BR00118047 MAPK8 final crispr D13 U2OS 96 394 Polylobed 0.1364983243404112 5.4340459571956484e-05 BR00118048 PPAT final crispr E13 U2OS 96 554 Polylobed +0.15782864870085966 6.312953121935461e-05 BR00118047 ANXA1 final crispr F24 U2OS 96 408 Polylobed +0.13451327433628318 7.107381727149033e-05 BR00118047 DDR2 final crispr A03 U2OS 96 565 Polylobed +0.1969111969111969 8.309693501313532e-05 BR00118045 FFAR2 final crispr A24 U2OS 96 259 Polylobed +0.10524568267350419 9.53238726386941e-05 BR00118045 CYP1A2 final crispr K22 U2OS 96 889 Polylobed +0.10321177372579086 9.849585632976125e-05 BR00118045 LYN final crispr F22 U2OS 96 916 Polylobed +0.15058453504243072 0.0001437535839060861 BR00118047 ADRA2B final crispr J14 U2OS 96 411 Polylobed +0.11739130434782609 0.00014619425683917137 BR00118047 HTR3A final crispr O20 U2OS 96 690 Polylobed +0.09099099099099099 0.00020235018345183438 BR00118047 KCNQ2 final crispr P13 U2OS 96 1110 Polylobed +0.10681476846057572 0.00020383260662620617 BR00118047 SSTR2 final crispr C02 U2OS 96 800 Polylobed +0.13262160569382112 0.0002043202228218467 BR00118045 RPL3 final crispr H11 U2OS 96 513 Polylobed +0.1091873640191009 0.00023321673947040034 BR00118045 HIF1A final crispr A01 U2OS 96 752 Polylobed +0.14367528798087373 0.00024892075039383173 BR00118047 PPAT final crispr E13 U2OS 96 430 Polylobed +0.11774161141249749 0.00027208220539297605 BR00118045 SLCO2B1 final crispr A21 U2OS 96 630 Polylobed +0.11130113214532182 0.0002860042095600472 BR00118047 SIRT2 final crispr P01 U2OS 96 703 Polylobed +0.11908646003262642 0.00033090087390128783 BR00118045 ITGB2 final crispr A17 U2OS 96 613 Polylobed +0.11295180722891567 0.00041388300827126316 BR00118047 GJB4 final crispr H01 U2OS 96 664 Polylobed +0.1251115075825156 0.0004280969137220341 BR00118046 DHH final crispr F05 U2OS 96 531 Polylobed +0.10380885264606195 0.0004370605031103066 BR00118046 SLC7A11 final crispr A05 U2OS 96 774 Polylobed +0.11276662333285184 0.0004596343225069583 BR00118046 PIK3CG final crispr I08 U2OS 96 645 Polylobed +0.11143181976379962 0.0005130336575883957 BR00118047 S1PR1 final crispr P23 U2OS 96 658 Polylobed +0.11582381729200653 0.0005302931896419406 BR00118045 ANXA1 final crispr F24 U2OS 96 613 Polylobed +0.11762574476727028 0.0005379565389678197 BR00118047 NAMPT final crispr I09 U2OS 96 587 Polylobed +0.1279176501442434 0.0005392069116965015 BR00118048 ANXA1 final crispr F24 U2OS 96 492 Polylobed +0.15920521065215598 0.0005911914327297779 BR00118048 FOXM1 final crispr A19 U2OS 96 312 Polylobed +0.10138336240031155 0.0006659339482344002 BR00118045 KCNJ1 final crispr F03 U2OS 96 770 Polylobed +0.08965771707226268 0.0008655718971034072 BR00118045 PAK1 final crispr N06 U2OS 96 949 Polylobed +0.09866447795071336 0.0010061750176811528 BR00118046 TGM2 final crispr B09 U2OS 96 771 Polylobed +0.15633663366336634 0.0010685964243728504 BR00118047 CDK4 final crispr B15 U2OS 96 303 Polylobed +0.09225512528473805 0.0011296108139364261 BR00118045 KDR final crispr J02 U2OS 96 878 Polylobed +0.12686112776017733 0.0011333878323178694 BR00118047 TUBB3 final crispr F19 U2OS 96 458 Polylobed +0.088765782163263 0.0011980893506261469 BR00118047 EDNRB final crispr K06 U2OS 96 931 Polylobed +0.12268615170494085 0.001229995949163662 BR00118047 CDK9 final crispr I20 U2OS 96 480 Polylobed +0.135 0.0013468720321565051 BR00118047 GUCY1B1 final crispr H21 U2OS 96 400 Polylobed +0.08305595006641571 0.0013768363464218632 BR00118045 P2RY12 final crispr O21 U2OS 96 1045 Polylobed +0.10471532245997306 0.0013788991734606467 BR00118045 TGFBR1 final crispr P24 U2OS 96 656 Polylobed +0.08678748275940036 0.0014774188496364743 BR00118045 DHH final crispr K21 U2OS 96 940 Polylobed +0.0995113433861546 0.0016935809955416162 BR00118047 OPRL1 final crispr A11 U2OS 96 707 Polylobed +0.11026276008701316 0.0017326261678997888 BR00118046 GAA final crispr L17 U2OS 96 569 Polylobed +0.12049404695671526 0.00178748967910244 BR00118046 DCK final crispr I07 U2OS 96 473 Polylobed +0.10852986866261827 0.0018257102107539361 BR00118048 FLT3 final crispr G16 U2OS 96 584 Polylobed +0.09645349303781287 0.002013895618640188 BR00118046 BAX final crispr E06 U2OS 96 731 Polylobed +0.09774971591363775 0.0020858242451069643 BR00118045 PIK3CG final crispr E22 U2OS 96 708 Polylobed +0.0886079692864421 0.002145505709024742 BR00118047 GPR119 final crispr G23 U2OS 96 863 Polylobed +0.1099290780141844 0.0021762019786045936 BR00118045 FOXM1 final crispr A19 U2OS 96 564 Polylobed +0.08941176470588236 0.0022267360444964655 BR00118047 KCNN4 final crispr K01 U2OS 96 850 Polylobed +0.08478871405721088 0.002242971373570072 BR00118045 CA5A final crispr I02 U2OS 96 928 Polylobed +0.10202793047095528 0.002325010465806934 BR00118047 KDR final crispr O18 U2OS 96 636 Polylobed +0.0816409629968952 0.0023275044361709706 BR00118048 LPAR1 final crispr L01 U2OS 96 999 Polylobed +0.1126118067978533 0.002502831183970279 BR00118047 S1PR1 final crispr A18 U2OS 96 520 Polylobed +0.11507936507936507 0.0025046521474405762 BR00118047 DCK final crispr I07 U2OS 96 504 Polylobed +0.10027349977330233 0.0028791473786689563 BR00118047 S1PR2 final crispr K02 U2OS 96 642 Polylobed +0.11056946929039953 0.003177927482541778 BR00118047 ADRA2B final crispr H22 U2OS 96 520 Polylobed +0.0766992820626711 0.003184489377949592 BR00118045 GLRA3 final crispr E21 U2OS 96 1079 Polylobed +0.10210696920583469 0.003196882694497378 BR00118046 BRD4 final crispr J16 U2OS 96 617 Polylobed +0.0859284472769409 0.0032181809661500273 BR00118045 SLC7A11 final crispr A05 U2OS 96 863 Polylobed +0.1103636635737803 0.003292064640952051 BR00118048 PIK3CG final crispr I08 U2OS 96 520 Polylobed +0.09557774607703282 0.003293643038680946 BR00118045 CACNA2D3 final crispr N24 U2OS 96 701 Polylobed +0.08102823945374368 0.0034715347717227027 BR00118048 CCR1 final crispr O17 U2OS 96 957 Polylobed +0.10886537126995142 0.003515073711344644 BR00118048 IL1B final crispr H18 U2OS 96 528 Polylobed +0.09989352383649877 0.0036237846115992466 BR00118047 UGT1A9 final crispr J01 U2OS 96 618 Polylobed +0.10988204536246397 0.0037168368966675365 BR00118047 CDK7 final crispr I14 U2OS 96 514 Polylobed +0.10234899328859061 0.003864878267396213 BR00118047 ITGB2 final crispr A17 U2OS 96 596 Polylobed +0.0860571408299138 0.004148795754202616 BR00118048 SIRT2 final crispr P01 U2OS 96 824 Polylobed +0.11378968939236951 0.0042579692286429036 BR00118045 GABRB2 final crispr L22 U2OS 96 465 Polylobed +0.09015328516927405 0.0044077566853450165 BR00118046 CA14 final crispr C19 U2OS 96 746 Polylobed +0.0974561829060467 0.004447804008434257 BR00118047 MMP2 final crispr D14 U2OS 96 635 Polylobed +0.13410003650967506 0.004464658501522777 BR00118046 TUBB4B final crispr J13 U2OS 96 330 Polylobed +0.09841765433824709 0.004528730825399033 BR00118047 KCNMA1 final crispr E23 U2OS 96 621 Polylobed +0.11468189314559324 0.004849150262686145 BR00118047 AVPR1A final crispr J07 U2OS 96 447 Polylobed +0.10725443746352181 0.004997745140602581 BR00118048 KCNQ2 final crispr A16 U2OS 96 513 Polylobed +0.09966777408637874 0.0050323379408693915 BR00118047 CACNB4 final crispr I23 U2OS 96 602 Polylobed +0.09799092050613349 0.005157553622393691 BR00118047 AGER final crispr K20 U2OS 96 609 Polylobed +0.0878223650502086 0.005273447686174314 BR00118046 PRKCE final crispr I17 U2OS 96 757 Polylobed +0.14682595987400324 0.005642133035179325 BR00118047 RPL23A final crispr M18 U2OS 96 262 Polylobed +0.16397124887690925 0.005865943868250011 BR00118047 RPL23A final crispr G14 U2OS 96 210 Polylobed +0.12110294762550516 0.006242374354672521 BR00118045 CCND1 final crispr B23 U2OS 96 383 Polylobed +0.08692358226667797 0.006377464695256468 BR00118045 HSP90AB1 final crispr B04 U2OS 96 752 Polylobed +0.11653907779953712 0.00645690664723 BR00118047 DYRK1B final crispr N16 U2OS 96 411 Polylobed +0.10853080977562306 0.006463361542060122 BR00118047 USP1 final crispr N12 U2OS 96 481 Polylobed +0.08495752123938032 0.006515496640426747 BR00118046 PRKCE final crispr K05 U2OS 96 783 Polylobed +0.08684519930872311 0.006576257720652287 BR00118046 KCNN4 final crispr K01 U2OS 96 751 Polylobed +0.08580210110811866 0.006617968765613108 BR00118048 CACNB4 final crispr I23 U2OS 96 766 Polylobed +0.09564209855798271 0.006938899246324221 BR00118046 GJB4 final crispr H01 U2OS 96 604 Polylobed +0.11658255748130127 0.006985624198619329 BR00118047 IL1B final crispr H18 U2OS 96 409 Polylobed +0.09334397981112359 0.007045100872083244 BR00118046 IL1B final crispr H06 U2OS 96 636 Polylobed +0.13462046204620462 0.007404270150439927 BR00118047 TUBB3 final crispr K11 U2OS 96 303 Polylobed +0.08791592437502868 0.007611166378956272 BR00118045 SIRT2 final crispr P01 U2OS 96 709 Polylobed +0.07251427685733723 0.007856597974730442 BR00118045 RET final crispr I03 U2OS 96 1039 Polylobed +0.18677375256322626 0.008003150357071403 BR00118046 RPL23A final crispr M18 U2OS 96 152 Polylobed +0.09444895309203051 0.00802547837154608 BR00118047 BRD4 final crispr J16 U2OS 96 606 Polylobed 0.19718992248062014 8.066748408966855e-08 BR00118047 RPL3 final crispr K04 U2OS 96 432 Prometaphase 0.2252475949941826 2.09285504735227e-06 BR00118047 RPL23A final crispr M18 U2OS 96 262 Prometaphase 0.17459723410322212 5.9315518952648876e-05 BR00118045 RPL23A final crispr M18 U2OS 96 334 Prometaphase @@ -1039,6 +10309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.11819583521014518 0.0004605004200282732 BR00118047 S1PR2 final crispr J23 U2OS 96 589 Prometaphase 0.0965481868179084 0.0005684209717363272 BR00118046 LPAR1 final crispr L01 U2OS 96 864 Prometaphase 0.09339239879424552 0.0005910764550760033 BR00118045 LYN final crispr F22 U2OS 96 916 Prometaphase +0.10942428162381361 0.0008580261217701881 BR00118047 TNF final crispr I10 U2OS 96 643 Prometaphase +0.10395536607105132 0.0008819736779799369 BR00118047 SIRT2 final crispr P01 U2OS 96 703 Prometaphase +0.0889244435795342 0.0009880901488575752 BR00118046 HSD11B1 final crispr O23 U2OS 96 949 Prometaphase +0.09914013266122072 0.0010388225574207708 BR00118047 IGF1R final crispr M22 U2OS 96 753 Prometaphase +0.0990363911947191 0.0011694101005845252 BR00118046 KCNN4 final crispr K01 U2OS 96 751 Prometaphase +0.10901218443979376 0.0012238793153821169 BR00118047 USP1 final crispr K18 U2OS 96 618 Prometaphase +0.1091438768489852 0.0012465693662640762 BR00118047 TUBB final crispr K13 U2OS 96 608 Prometaphase +0.10242377018090668 0.0012666222469652417 BR00118046 OPRM1 final crispr P22 U2OS 96 696 Prometaphase +0.1326530612244898 0.001996585120019757 BR00118045 RPL3 final crispr K04 U2OS 96 392 Prometaphase +0.09822877189545284 0.002139777603680574 BR00118046 GJB4 final crispr N01 U2OS 96 699 Prometaphase +0.09047113470471135 0.0021541795454055983 BR00118048 MAPK8 final crispr D07 U2OS 96 825 Prometaphase +0.1011067542170352 0.0021928688409571344 BR00118047 S1PR1 final crispr P23 U2OS 96 658 Prometaphase +0.0886060502866224 0.002593892199288938 BR00118046 CHRM2 final crispr O22 U2OS 96 839 Prometaphase +0.09611122305057425 0.002607349635908262 BR00118045 IL1B final crispr H06 U2OS 96 709 Prometaphase +0.0935330906309318 0.0026498610966275457 BR00118046 LYN final crispr F22 U2OS 96 751 Prometaphase +0.11200980392156863 0.00287710317334804 BR00118048 CACNB4 final crispr B01 U2OS 96 512 Prometaphase +0.14067278287461774 0.0030600307056199336 BR00118047 TUBB final crispr J17 U2OS 96 327 Prometaphase +0.07595586814609552 0.0032368417628899494 BR00118045 CYP2A6 final crispr C07 U2OS 96 1102 Prometaphase +0.16478205702343635 0.003265157672695279 BR00118048 RPL23A final crispr M18 U2OS 96 231 Prometaphase +0.1263876608704195 0.003959943574755575 BR00118047 F10 final crispr H15 U2OS 96 377 Prometaphase +0.19762474367737526 0.004014719998520318 BR00118046 RPL23A final crispr M18 U2OS 96 152 Prometaphase +0.09767441860465116 0.00423076471321664 BR00118047 HTR2C final crispr M12 U2OS 96 645 Prometaphase +0.13636363636363635 0.004283428593878597 BR00118047 KCNN4 final crispr A22 U2OS 96 330 Prometaphase +0.09286665680035519 0.004446246347810038 BR00118047 TGFBR1 final crispr P24 U2OS 96 696 Prometaphase +0.07707317073170732 0.004522466103712169 BR00118046 P3H1 final crispr N02 U2OS 96 1025 Prometaphase +0.09115822296515366 0.005179134688571769 BR00118047 ASIC1 final crispr M20 U2OS 96 704 Prometaphase +0.0798814289627938 0.006271128612232813 BR00118045 CYP1A2 final crispr K22 U2OS 96 889 Prometaphase +0.1834319526627219 0.006680982573926605 BR00118047 PLK1 final crispr G09 U2OS 96 169 Prometaphase +0.09020110929248373 0.006716849935584432 BR00118045 PPAT final crispr E13 U2OS 96 687 Prometaphase +0.08345204290525561 0.007020649134174192 BR00118045 FLT3 final crispr J20 U2OS 96 797 Prometaphase +0.079117644078274 0.007350570879500666 BR00118046 CSF1R final crispr C08 U2OS 96 888 Prometaphase +0.1153600635937707 0.007855318974978624 BR00118047 IL1B final crispr H18 U2OS 96 409 Prometaphase +0.0719560231466799 0.008402900519674295 BR00118045 P2RY12 final crispr O21 U2OS 96 1045 Prometaphase +0.0785876993166287 0.00880968834571079 BR00118045 KDR final crispr J02 U2OS 96 878 Prometaphase +0.07530508706979296 0.009330337352904863 BR00118045 GPR55 final crispr C21 U2OS 96 935 Prometaphase +0.07465049822769887 0.009351645274200574 BR00118045 PAK1 final crispr N06 U2OS 96 949 Prometaphase +0.09192802962543686 0.010247442013638485 BR00118048 ERBB2 final crispr H12 U2OS 96 613 Prometaphase +0.08053825242226263 0.010663569551908846 BR00118046 PRKCB final crispr N04 U2OS 96 793 Prometaphase +0.08234490402679652 0.011138154255159828 BR00118046 FPR1 final crispr N22 U2OS 96 757 Prometaphase +0.07220845535781333 0.01171697276943495 BR00118046 CDK4 final crispr P03 U2OS 96 966 Prometaphase +0.10574829474397493 0.01190439040844866 BR00118047 AVPR1A final crispr J07 U2OS 96 447 Prometaphase +0.08379120879120878 0.012027093598459682 BR00118047 ALK final crispr G06 U2OS 96 728 Prometaphase +0.07188331033089844 0.012032266533215527 BR00118045 DNMT3A final crispr L04 U2OS 96 976 Prometaphase +0.08141882483987747 0.012121721987503801 BR00118047 OPRM1 final crispr C23 U2OS 96 756 Prometaphase +0.0693472316935766 0.012498924342793764 BR00118045 EZH2 final crispr C05 U2OS 96 1043 Prometaphase +0.09214904213767591 0.013090602131295474 BR00118047 FPR1 final crispr I18 U2OS 96 583 Prometaphase +0.1498017361483228 0.013349836172186921 BR00118047 KCNN1 final crispr B24 U2OS 96 217 Prometaphase +0.0819880767721318 0.013492609950335958 BR00118047 CCR1 final crispr O17 U2OS 96 733 Prometaphase +0.08165334539415149 0.013771072700333096 BR00118047 BRAF final crispr F20 U2OS 96 736 Prometaphase +0.12656765676567658 0.014054037442316331 BR00118047 TUBB3 final crispr K11 U2OS 96 303 Prometaphase +0.09769955226184962 0.014191065930442321 BR00118048 AGER final crispr K20 U2OS 96 510 Prometaphase +0.09029753358363134 0.01605073887590191 BR00118046 S1PR1 final crispr P23 U2OS 96 579 Prometaphase +0.0738801443544994 0.016203680922834578 BR00118046 OPRM1 final crispr C23 U2OS 96 869 Prometaphase +0.0775 0.016347766245903225 BR00118045 GPR119 final crispr G23 U2OS 96 800 Prometaphase +0.08092244150450378 0.016408372574749433 BR00118046 RGS4 final crispr N11 U2OS 96 722 Prometaphase +0.08003451643444487 0.016488811138918414 BR00118048 KCNK1 final crispr C17 U2OS 96 732 Prometaphase +0.07329511575115333 0.016955076597041735 BR00118048 HTR3A final crispr O02 U2OS 96 877 Prometaphase +0.08766233766233766 0.01754745726684442 BR00118047 CYP3A4 final crispr D20 U2OS 96 616 Prometaphase +0.08221624183338411 0.017584955333947928 BR00118046 IL1B final crispr H18 U2OS 96 687 Prometaphase +0.0712175332355585 0.01764004324574425 BR00118046 MMP2 final crispr D14 U2OS 96 920 Prometaphase +0.0819275287207394 0.018451096682096223 BR00118047 JAK1 final crispr M21 U2OS 96 680 Prometaphase +0.09460866778819194 0.01855370157773201 BR00118048 KCNQ2 final crispr A16 U2OS 96 513 Prometaphase +0.0718232044198895 0.018745547982209437 BR00118045 DDR2 final crispr B03 U2OS 96 905 Prometaphase +0.08444122680005266 0.01909092621856319 BR00118047 CACNG1 final crispr N23 U2OS 96 642 Prometaphase +0.10369319743598202 0.019136520942869047 BR00118045 FOXM1 final crispr F23 U2OS 96 426 Prometaphase +0.08644844693701467 0.019449510821165195 BR00118046 DDR2 final crispr B03 U2OS 96 608 Prometaphase +0.08425840609597356 0.019507660369971164 BR00118047 S1PR2 final crispr K02 U2OS 96 642 Prometaphase +0.0726381628209866 0.0210804485733175 BR00118048 GJB4 final crispr N01 U2OS 96 849 Prometaphase +0.07686343031170617 0.02139194409671063 BR00118046 HBB final crispr F21 U2OS 96 754 Prometaphase +0.10825867861142217 0.02143715874430804 BR00118045 HCK final crispr H23 U2OS 96 376 Prometaphase +0.07612387612387612 0.02158348353548535 BR00118045 KCNJ1 final crispr F03 U2OS 96 770 Prometaphase +0.08057553956834532 0.021911923888123776 BR00118046 GUCY1B1 final crispr N08 U2OS 96 695 Prometaphase +0.08269525267993874 0.022958380938702578 BR00118047 PLA2G1B final crispr L20 U2OS 96 653 Prometaphase +0.09663865546218488 0.023412399102090756 BR00118047 ATM final crispr G12 U2OS 96 476 Prometaphase +0.06850983893166686 0.02385612975962494 BR00118045 CA5A final crispr I02 U2OS 96 928 Prometaphase +0.07834887604983258 0.02441119451856574 BR00118047 OPRL1 final crispr A11 U2OS 96 707 Prometaphase +0.075842402130381 0.02447780331795973 BR00118046 SLC7A11 final crispr P05 U2OS 96 756 Prometaphase +0.07903577113177515 0.024739655928839116 BR00118046 UGT1A9 final crispr J01 U2OS 96 690 Prometaphase +0.07710398590783876 0.024799867233664057 BR00118047 CA14 final crispr G15 U2OS 96 731 Prometaphase +0.0752749444412787 0.02488445128709272 BR00118045 KCNJ1 final crispr E14 U2OS 96 759 Prometaphase +0.08427876823338736 0.024947260307144562 BR00118046 PTPN2 final crispr A15 U2OS 96 617 Prometaphase +0.07913669064748201 0.025712253349546892 BR00118046 TBXAS1 final crispr E24 U2OS 96 695 Prometaphase +0.08166409861325115 0.02634354690422116 BR00118045 LCK final crispr O15 U2OS 96 649 Prometaphase +0.07569721115537849 0.026706341771839007 BR00118045 KCTD16 final crispr D08 U2OS 96 753 Prometaphase +0.0851574636350798 0.026890324482220354 BR00118047 PDE7A final crispr C10 U2OS 96 584 Prometaphase +0.08005302993558341 0.027331376000849093 BR00118047 PLD1 final crispr F04 U2OS 96 659 Prometaphase +0.09009947573598602 0.027469049636160855 BR00118047 RET final crispr D17 U2OS 96 519 Prometaphase +0.09967813540510544 0.027740206921418934 BR00118047 AVPR1A final crispr D05 U2OS 96 425 Prometaphase +0.08267758857929136 0.028502846024990453 BR00118047 GRIN2A final crispr P09 U2OS 96 608 Prometaphase +0.09906220588894367 0.028786432988890477 BR00118048 CSK final crispr B11 U2OS 96 421 Prometaphase 0.275 4.859512816331384e-19 BR00118047 AURKB final crispr C13 U2OS 96 560 SmallIrregular 0.2944838816104554 3.372427012590933e-17 BR00118046 AURKB final crispr C13 U2OS 96 434 SmallIrregular 0.35208613225854607 2.8428284505618367e-13 BR00118048 RPL23A final crispr M18 U2OS 96 231 SmallIrregular @@ -1049,6 +10409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.217743953874248 3.935912251254457e-10 BR00118048 AURKB final crispr C13 U2OS 96 466 SmallIrregular 0.13603603603603603 2.2715869190529e-09 BR00118047 KCNQ2 final crispr P13 U2OS 96 1110 SmallIrregular 0.35919343814080656 2.8192550572346558e-09 BR00118046 RPL23A final crispr M18 U2OS 96 152 SmallIrregular +0.1400198609731877 5.045449359827048e-09 BR00118047 SCNN1G final crispr P15 U2OS 96 1007 SmallIrregular +0.24848306408254178 4.4434217570806595e-08 BR00118046 RPL23A final crispr G14 U2OS 96 278 SmallIrregular +0.2065326633165829 5.742357929644365e-08 BR00118045 RPL23A final crispr G14 U2OS 96 400 SmallIrregular +0.20047169811320756 7.229819491898444e-08 BR00118045 TUBB4B final crispr J13 U2OS 96 424 SmallIrregular +0.28014375561545374 7.655789626786821e-08 BR00118047 RPL23A final crispr G14 U2OS 96 210 SmallIrregular +0.17776786599266528 8.185448699505479e-08 BR00118046 DHH final crispr F05 U2OS 96 531 SmallIrregular +0.28648514851485146 8.884834906857657e-08 BR00118048 PLK1 final crispr G09 U2OS 96 200 SmallIrregular +0.23277406955302185 3.7269490051984707e-07 BR00118048 RPL23A final crispr G14 U2OS 96 278 SmallIrregular +0.18016192406123052 4.894401930175926e-07 BR00118047 TUBB3 final crispr F19 U2OS 96 458 SmallIrregular +0.16331850527783984 8.208334526292024e-07 BR00118046 CDK2 final crispr F08 U2OS 96 546 SmallIrregular +0.13132063972157787 8.912017355192511e-07 BR00118045 GJB4 final crispr N01 U2OS 96 839 SmallIrregular +0.1535340022296544 1.2352253673709929e-06 BR00118046 JAK1 final crispr J09 U2OS 96 600 SmallIrregular +0.11559790280298447 1.4201416481760628e-06 BR00118047 PTK2B final crispr N15 U2OS 96 1044 SmallIrregular +0.136182221468735 1.5089560340512722e-06 BR00118045 HSP90AB1 final crispr B04 U2OS 96 752 SmallIrregular +0.2222222222222222 1.8973769071071668e-06 BR00118045 PLK1 final crispr G09 U2OS 96 279 SmallIrregular +0.19949386940404903 2.6539779535982305e-06 BR00118045 RPL23A final crispr M18 U2OS 96 334 SmallIrregular +0.14929364066160689 2.7671787466060365e-06 BR00118046 CACNB4 final crispr I23 U2OS 96 599 SmallIrregular +0.09964991844691093 3.398702591043636e-06 BR00118047 RGS4 final crispr N11 U2OS 96 1323 SmallIrregular +0.15114356572058418 3.6055278741479696e-06 BR00118046 CTSG final crispr L12 U2OS 96 570 SmallIrregular +0.12832962603665488 4.610439022596599e-06 BR00118046 PRKCE final crispr K05 U2OS 96 783 SmallIrregular +0.13600524101727976 4.977597422670663e-06 BR00118045 PPAT final crispr E13 U2OS 96 687 SmallIrregular +0.13623188405797101 5.324480110988926e-06 BR00118047 HTR3A final crispr O20 U2OS 96 690 SmallIrregular +0.15073819598100488 5.449233531369838e-06 BR00118048 PPAT final crispr E13 U2OS 96 554 SmallIrregular +0.1710932405998696 5.4875001654983815e-06 BR00118047 PPAT final crispr E13 U2OS 96 430 SmallIrregular +0.14521902513288196 7.3899043248536595e-06 BR00118047 NAMPT final crispr I09 U2OS 96 587 SmallIrregular +0.14969253780953964 7.745065555116827e-06 BR00118048 GAA final crispr L18 U2OS 96 547 SmallIrregular +0.12543465242694035 8.28142817674161e-06 BR00118045 FLT3 final crispr G16 U2OS 96 777 SmallIrregular +0.13504489663333255 1.0663669686162357e-05 BR00118047 S1PR1 final crispr P23 U2OS 96 658 SmallIrregular +0.12572742631875353 1.0734618823712812e-05 BR00118045 DYRK1B final crispr N16 U2OS 96 756 SmallIrregular +0.1694142780843867 1.1987254681636954e-05 BR00118047 DYRK1B final crispr N16 U2OS 96 411 SmallIrregular +0.12402088772845953 1.4939810730048196e-05 BR00118046 CDC25A final crispr D06 U2OS 96 766 SmallIrregular +0.17146080090242527 1.542520286362069e-05 BR00118047 MAPK8 final crispr D13 U2OS 96 394 SmallIrregular +0.1344 2.4384095191437786e-05 BR00118045 CSF1R final crispr J15 U2OS 96 625 SmallIrregular +0.12466477284014382 2.926694917992275e-05 BR00118047 ATP5F1D final crispr G21 U2OS 96 710 SmallIrregular +0.13739187107477188 3.0511591269563566e-05 BR00118047 CASP3 final crispr E11 U2OS 96 582 SmallIrregular +0.14772476253589573 3.0742192629480344e-05 BR00118047 ERBB2 final crispr I11 U2OS 96 503 SmallIrregular +0.14278181329028786 3.594473312150195e-05 BR00118047 CYP3A4 final crispr D04 U2OS 96 531 SmallIrregular +0.1293369926332515 3.8488096268809806e-05 BR00118046 PIK3CG final crispr I08 U2OS 96 645 SmallIrregular +0.18759075907590758 3.929324640230826e-05 BR00118047 TUBB3 final crispr K11 U2OS 96 303 SmallIrregular +0.16497543906870332 4.247412429850503e-05 BR00118047 CSF1R final crispr J15 U2OS 96 385 SmallIrregular +0.13887171509676047 4.348667522389412e-05 BR00118047 PTGIS final crispr I16 U2OS 96 546 SmallIrregular +0.13504273504273503 4.545915514784975e-05 BR00118046 HSP90AB1 final crispr B04 U2OS 96 585 SmallIrregular +0.13354798504362278 5.408296101322209e-05 BR00118045 PLA2G1B final crispr L20 U2OS 96 580 SmallIrregular +0.14716852578157075 5.6556023350591526e-05 BR00118046 CDK7 final crispr E12 U2OS 96 479 SmallIrregular +0.11729491693314814 5.877622317855104e-05 BR00118046 CA14 final crispr C19 U2OS 96 746 SmallIrregular +0.11144927536231884 6.179863370532784e-05 BR00118046 RET final crispr D17 U2OS 96 828 SmallIrregular +0.11618798955613577 6.351822673647497e-05 BR00118045 PDE7A final crispr C22 U2OS 96 766 SmallIrregular +0.14458984998404087 6.695673693498175e-05 BR00118047 USP1 final crispr N12 U2OS 96 481 SmallIrregular +0.11323006386732201 6.794287409592401e-05 BR00118045 CDK4 final crispr P03 U2OS 96 797 SmallIrregular +0.12657356509681572 6.851476431677991e-05 BR00118047 KDR final crispr O18 U2OS 96 636 SmallIrregular +0.16182742782152232 7.355713024924284e-05 BR00118048 TUBB3 final crispr K11 U2OS 96 384 SmallIrregular +0.12099457714155679 7.659678629808511e-05 BR00118047 DHH final crispr K21 U2OS 96 682 SmallIrregular +0.11058017635362337 8.014664841797527e-05 BR00118045 CYP2A6 final crispr O04 U2OS 96 821 SmallIrregular +0.1271995832368604 8.493235822224406e-05 BR00118047 PRKCE final crispr I17 U2OS 96 617 SmallIrregular +0.12775523453984744 8.499568838497043e-05 BR00118047 BRD4 final crispr J16 U2OS 96 606 SmallIrregular +0.14378190360030718 9.355829943580264e-05 BR00118045 TUBB3 final crispr K11 U2OS 96 471 SmallIrregular +0.12635549269212634 0.0001058221731553937 BR00118045 RGS4 final crispr N11 U2OS 96 609 SmallIrregular +0.12582367704384045 0.00010785885282267666 BR00118047 PAK1 final crispr K10 U2OS 96 610 SmallIrregular +0.1266220735785953 0.00012038028039579433 BR00118046 RNASE1 final crispr I13 U2OS 96 600 SmallIrregular +0.14860034453057708 0.00012343350375819425 BR00118047 RPL3 final crispr K04 U2OS 96 432 SmallIrregular +0.12162555509945143 0.00014525782024558666 BR00118047 MMP2 final crispr D14 U2OS 96 635 SmallIrregular +0.1401624568821631 0.0001519186095003182 BR00118046 DCK final crispr I07 U2OS 96 473 SmallIrregular +0.12358538990967458 0.0001534608249817228 BR00118045 ADRA2B final crispr H22 U2OS 96 611 SmallIrregular +0.11278872731981107 0.0001597649090589968 BR00118045 KDR final crispr O18 U2OS 96 731 SmallIrregular +0.1465223696224287 0.00016216409805883423 BR00118047 JAK1 final crispr J09 U2OS 96 433 SmallIrregular +0.12037037037037036 0.00016472171974970317 BR00118046 MAPK8 final crispr D13 U2OS 96 648 SmallIrregular +0.13256135499481508 0.00016841825633982164 BR00118046 PLA2G1B final crispr J11 U2OS 96 526 SmallIrregular +0.10368379875952069 0.00017416103988626995 BR00118047 GPR119 final crispr G23 U2OS 96 863 SmallIrregular +0.1196319018404908 0.00017454576390846154 BR00118047 CA5A final crispr M01 U2OS 96 652 SmallIrregular +0.12563667232597622 0.00018034658019967038 BR00118048 CATSPER4 final crispr P02 U2OS 96 589 SmallIrregular +0.11051930758988016 0.00020498387513251623 BR00118045 HIF1A final crispr M24 U2OS 96 751 SmallIrregular +0.12462581636687386 0.00020711136592087257 BR00118046 S1PR1 final crispr P23 U2OS 96 579 SmallIrregular +0.1183471431164486 0.00022227950118988672 BR00118047 DYRK1B final crispr K14 U2OS 96 639 SmallIrregular +0.12653739329525923 0.000227362337636365 BR00118046 CDK2 final crispr L19 U2OS 96 561 SmallIrregular +0.22239737274220034 0.0002489607462930161 BR00118046 PLK1 final crispr G09 U2OS 96 175 SmallIrregular +0.11269614835948645 0.0002685690757958 BR00118045 CDK9 final crispr I20 U2OS 96 701 SmallIrregular +0.11353033669902408 0.00027902694132571576 BR00118045 COMT final crispr A12 U2OS 96 678 SmallIrregular +0.12544802867383512 0.0003024885901624775 BR00118046 ASIC1 final crispr J04 U2OS 96 558 SmallIrregular +0.1475 0.0003254839625295495 BR00118047 GUCY1B1 final crispr H21 U2OS 96 400 SmallIrregular +0.10825439783491204 0.00034281893606283233 BR00118045 DNMT3A final crispr L06 U2OS 96 739 SmallIrregular +0.11558866110512965 0.00034313527175737393 BR00118046 ADRA2B final crispr H22 U2OS 96 639 SmallIrregular +0.12821883631827496 0.00034367161075693096 BR00118048 CYP3A4 final crispr D04 U2OS 96 522 SmallIrregular +0.11831442463533225 0.00035019333120600625 BR00118046 BRD4 final crispr J16 U2OS 96 617 SmallIrregular +0.10421845904867753 0.0003552611275761782 BR00118045 BRD4 final crispr M19 U2OS 96 786 SmallIrregular +0.1211727781119535 0.0003554294307532974 BR00118046 PPAT final crispr E13 U2OS 96 578 SmallIrregular +0.12150358110723965 0.00036828698478447695 BR00118047 P3H1 final crispr N02 U2OS 96 576 SmallIrregular +0.11748607488972601 0.0003844341189819909 BR00118047 AGER final crispr K20 U2OS 96 609 SmallIrregular +0.11062077205263689 0.0003862855718345214 BR00118045 S1PR1 final crispr A18 U2OS 96 688 SmallIrregular +0.10031185642836128 0.0004241830109877171 BR00118045 CA5A final crispr M01 U2OS 96 825 SmallIrregular +0.10418395164157876 0.0004270883465475105 BR00118045 KCNJ1 final crispr F03 U2OS 96 770 SmallIrregular 0.1634716155116887 5.496695746317113e-35 BR00116996 IGF1R final crispr M22 U2OS 144 2964 ADCCM 0.1888266424194568 9.476823431668614e-32 BR00116996 OPRM1 final crispr P22 U2OS 144 2002 ADCCM 0.1842696629213483 8.10909949134475e-27 BR00116996 CHRM2 final crispr O22 U2OS 144 1780 ADCCM @@ -1059,6 +10509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.13933506753267666 3.3066711606003496e-22 BR00116996 ALK final crispr I15 U2OS 144 2572 ADCCM 0.1673229311857932 4.74733983327924e-22 BR00116996 PDE3A final crispr P18 U2OS 144 1760 ADCCM 0.18233618233618235 8.36556707630909e-21 BR00116996 CACNA2D3 final crispr N24 U2OS 144 1404 ADCCM +0.15483216940752423 1.1616435060952641e-20 BR00116999 CACNA2D3 final crispr N24 U2OS 144 1932 ADCCM +0.1656672030726282 3.3147933028914123e-20 BR00116996 GRIN2A final crispr A23 U2OS 144 1642 ADCCM +0.17356475300400534 4.0712756852687484e-20 BR00116996 P2RY12 final crispr P19 U2OS 144 1498 ADCCM +0.18717992572322126 4.505889617231349e-20 BR00116996 GPR119 final crispr P21 U2OS 144 1280 ADCCM +0.17101827676240208 5.651327424766223e-20 BR00116996 S1PR1 final crispr P23 U2OS 144 1532 ADCCM +0.2009090909090909 7.853046266968859e-20 BR00116999 GHSR final crispr B20 U2OS 144 1100 ADCCM +0.11571047091989675 1.4487974067653013e-19 BR00116996 CYP1A2 final crispr K22 U2OS 144 3280 ADCCM +0.0959107180459044 1.7580228643902482e-19 BR00116998 TNF final crispr I10 U2OS 144 4750 ADCCM +0.15656602867592043 1.82358655756974e-19 BR00116996 HIF1A final crispr M24 U2OS 144 1772 ADCCM +0.18078668683812404 2.752080486154072e-19 BR00116996 BTK final crispr P17 U2OS 144 1322 ADCCM +0.15523059617547807 4.208342152058235e-19 BR00116996 F10 final crispr H07 U2OS 144 1778 ADCCM +0.15431373224984568 9.6287592408387e-19 BR00116996 HDAC3 final crispr G07 U2OS 144 1754 ADCCM +0.14335051586696534 1.3517855573734441e-18 BR00116996 CACNG1 final crispr N23 U2OS 144 2022 ADCCM +0.1496564419676168 2.5406002532465117e-18 BR00116996 OPRM1 final crispr C23 U2OS 144 1828 ADCCM +0.11850040356042607 3.01722685676215e-18 BR00116996 AKR1B1 final crispr L21 U2OS 144 2908 ADCCM +0.14779411082019572 4.1015690650894505e-18 BR00116996 CYP2A6 final crispr C07 U2OS 144 1856 ADCCM +0.20501482795569842 6.808305490937356e-18 BR00116999 TUBB final crispr J17 U2OS 144 948 ADCCM +0.13978718833327014 8.694752280241436e-18 BR00116996 BTK final crispr D24 U2OS 144 2028 ADCCM +0.1735592622010414 4.1346167972921394e-17 BR00116996 PARP3 final crispr F12 U2OS 144 1260 ADCCM +0.16149325270235076 4.154771814177717e-17 BR00116996 PORCN final crispr L13 U2OS 144 1458 ADCCM +0.1269296740994854 8.780107262504462e-17 BR00116996 ABL1 final crispr P20 U2OS 144 2332 ADCCM +0.2662835249042146 1.1135245174768456e-16 BR00116996 PLA2G1B final crispr J11 U2OS 144 522 ADCCM +0.15312715453560524 1.8814770958082927e-16 BR00116996 RET final crispr I03 U2OS 144 1562 ADCCM +0.12498593038016671 3.003705602718645e-16 BR00116996 HCK final crispr M23 U2OS 144 2316 ADCCM +0.15574285020798634 5.981088671404773e-16 BR00116996 PIK3CG final crispr I08 U2OS 144 1466 ADCCM +0.13402770071664702 6.71767495475195e-16 BR00116996 ALK final crispr G06 U2OS 144 1970 ADCCM +0.15025575447570333 8.180410167755575e-16 BR00116999 GUCY1B1 final crispr H21 U2OS 144 1564 ADCCM +0.13792901962561321 1.0495721871668489e-15 BR00116996 PLD1 final crispr F11 U2OS 144 1832 ADCCM +0.13309352517985612 1.9486511849762537e-15 BR00116996 ELANE final crispr N19 U2OS 144 1946 ADCCM +0.13789727714326483 2.128614071447114e-15 BR00116996 BAX final crispr L14 U2OS 144 1796 ADCCM +0.14588528678304238 2.6735045313479836e-15 BR00116996 SLCO2B1 final crispr A21 U2OS 144 1604 ADCCM +0.12037270998596436 3.822551543414613e-15 BR00116996 HPGDS final crispr P14 U2OS 144 2330 ADCCM +0.11806130903065451 4.53970926165277e-15 BR00116996 CCR1 final crispr O17 U2OS 144 2414 ADCCM +0.22383804780493433 1.0831170610799874e-14 BR00116998 TGFBR1 final crispr B08 U2OS 144 646 ADCCM +0.13313754459950414 1.515123002747598e-14 BR00116999 FPR1 final crispr I18 U2OS 144 1822 ADCCM +0.13162519448828594 2.1646459193171268e-14 BR00116999 MET final crispr E20 U2OS 144 1842 ADCCM +0.12678019814244681 2.91991633690279e-14 BR00116996 DYRK1B final crispr K14 U2OS 144 1970 ADCCM +0.1244604839902433 2.963455554804594e-14 BR00116996 FPR1 final crispr N22 U2OS 144 2038 ADCCM +0.1854947140861037 3.4808848372444386e-14 BR00116999 IL1B final crispr H18 U2OS 144 914 ADCCM +0.14310587220286217 4.921453986404692e-14 BR00116996 PTGIS final crispr I16 U2OS 144 1518 ADCCM +0.09455587392550144 5.38558383743576e-14 BR00116999 PDE3A final crispr P18 U2OS 144 3490 ADCCM +0.12497943378340451 5.4352259202952e-14 BR00116996 SLCO2B1 final crispr I24 U2OS 144 1982 ADCCM +0.1386715703960615 5.6325816274550183e-14 BR00116996 TUBB final crispr K13 U2OS 144 1606 ADCCM +0.16639112408457435 5.678566577877594e-14 BR00116996 PRKCE final crispr I17 U2OS 144 1114 ADCCM +0.11966604823747681 7.30528416138689e-14 BR00116997 DYRK1B final crispr K14 U2OS 144 2156 ADCCM +0.09416365824308062 3.0473438978253226e-13 BR00116997 HDAC6 final crispr L10 U2OS 144 3324 ADCCM +0.13241993243733055 3.761405018404347e-13 BR00116999 ADH1C final crispr P04 U2OS 144 1660 ADCCM +0.12305295950155763 4.042166935879772e-13 BR00116996 PRKCE final crispr K05 U2OS 144 1926 ADCCM +0.1505540447699595 4.817378240287114e-13 BR00116996 RGS4 final crispr E08 U2OS 144 1266 ADCCM +0.09482869724816229 5.048053725907501e-13 BR00116998 ALDH2 final crispr A10 U2OS 144 3212 ADCCM +0.13612581214233466 8.487992689992175e-13 BR00116996 ATM final crispr F14 U2OS 144 1524 ADCCM +0.10365148880599707 8.94845200054409e-13 BR00116997 CACNA2D3 final crispr N24 U2OS 144 2630 ADCCM +0.15236349099130148 1.0936143287259091e-12 BR00116999 CDK9 final crispr I20 U2OS 144 1204 ADCCM +0.11663131181994993 1.7992043746568496e-12 BR00116999 HIF1A final crispr M24 U2OS 144 2020 ADCCM +0.10648973078131863 1.904917781619086e-12 BR00116999 HDAC3 final crispr G07 U2OS 144 2428 ADCCM +0.09703536296701598 2.596665441217401e-12 BR00116996 VEGFA final crispr C24 U2OS 144 2900 ADCCM +0.1300251256281407 3.823372933438417e-12 BR00116996 HSD11B1 final crispr O23 U2OS 144 1592 ADCCM +0.12302782816699565 6.394580567044912e-12 BR00116996 KRAS final crispr F07 U2OS 144 1734 ADCCM +0.14128071319852142 6.850735631887472e-12 BR00116996 GLRA3 final crispr F16 U2OS 144 1314 ADCCM +0.15633186234354218 7.018463796364257e-12 BR00116996 CHRM3 final crispr B21 U2OS 144 1066 ADCCM +0.10223642172523961 8.25741675476817e-12 BR00116997 HSD11B1 final crispr O23 U2OS 144 2504 ADCCM +0.13560577003935984 1.258877361327955e-11 BR00116996 CDK9 final crispr I20 U2OS 144 1396 ADCCM +0.11790649791291052 1.4303792512681994e-11 BR00116999 FFAR4 final crispr E04 U2OS 144 1828 ADCCM +0.13030446172457996 1.7229329833838126e-11 BR00116996 SCNN1G final crispr P15 U2OS 144 1492 ADCCM +0.1171960569550931 2.4371058127576385e-11 BR00116999 PTPN2 final crispr B12 U2OS 144 1826 ADCCM +0.11258861262233413 4.014572528142629e-11 BR00116997 ADA final crispr O06 U2OS 144 1934 ADCCM +0.10247107805865527 4.948191189392925e-11 BR00116996 GPR55 final crispr C21 U2OS 144 2308 ADCCM +0.15862921318716056 5.965432453712292e-11 BR00116999 CDK9 final crispr M04 U2OS 144 956 ADCCM +0.11163032191069575 7.222753026941818e-11 BR00116996 ATP5F1D final crispr G21 U2OS 144 1926 ADCCM +0.12872468268378903 8.36468134356547e-11 BR00116996 S1PR2 final crispr J23 U2OS 144 1434 ADCCM +0.12748248052229527 9.632395521377839e-11 BR00116997 PTGIR final crispr G10 U2OS 144 1448 ADCCM +0.13048977896806563 1.1298455477804554e-10 BR00116996 VEGFA final crispr H02 U2OS 144 1372 ADCCM +0.11237804133682659 1.2820774348036525e-10 BR00116996 MMP2 final crispr E07 U2OS 144 1844 ADCCM +0.14332102034367405 1.3294771481782481e-10 BR00116996 KCNH7 final crispr P16 U2OS 144 1134 ADCCM +0.09991423670668954 1.4994640443021416e-10 BR00116996 P2RY12 final crispr O21 U2OS 144 2332 ADCCM +0.12999248992967843 1.64384915990784e-10 BR00116999 PAK4 final crispr M16 U2OS 144 1358 ADCCM +0.14971340213738574 2.0104222769552382e-10 BR00116996 CSF1R final crispr J15 U2OS 144 1018 ADCCM +0.13916176640147584 2.0424172238310437e-10 BR00116999 PTGIR final crispr G10 U2OS 144 1180 ADCCM +0.11619670460336334 2.2788810160284697e-10 BR00116996 GABRB2 final crispr L22 U2OS 144 1682 ADCCM +0.12002383642255025 2.9887300381655546e-10 BR00116996 TNF final crispr N17 U2OS 144 1554 ADCCM +0.1369747899159664 3.7856932190079874e-10 BR00116997 GPR55 final crispr H16 U2OS 144 1190 ADCCM +0.09580592105263158 3.921809509913966e-10 BR00116996 EDNRB final crispr K06 U2OS 144 2432 ADCCM +0.09833258482795525 4.358018113841846e-10 BR00116998 GABRB2 final crispr L22 U2OS 144 2290 ADCCM +0.1367644316577426 5.919292162084906e-10 BR00116997 ICAM1 final crispr C20 U2OS 144 1164 ADCCM +0.17125693744865453 6.240814103774038e-10 BR00116996 TGFBR1 final crispr B08 U2OS 144 734 ADCCM +0.08083832335329341 6.501899287168371e-10 BR00116999 ANXA1 final crispr G01 U2OS 144 3340 ADCCM +0.10469867211440245 9.224794871867816e-10 BR00116996 KCNQ2 final crispr P13 U2OS 144 1958 ADCCM +0.12412731776893626 9.433809487694071e-10 BR00116997 DYRK1B final crispr N16 U2OS 144 1384 ADCCM +0.13970111770295088 9.443236830733111e-10 BR00116998 CYP2A6 final crispr O04 U2OS 144 1092 ADCCM +0.13503512725941352 1.1700074447885495e-09 BR00116998 TNNC1 final crispr D09 U2OS 144 1156 ADCCM 0.22639268818588484 6.164690178271219e-44 BR00116999 CACNA2D3 final crispr N24 U2OS 144 1932 Anaphase 0.18268154745231677 1.2444261674004282e-43 BR00116996 IGF1R final crispr M22 U2OS 144 2964 Anaphase 0.24727838258164853 6.417309706807418e-35 BR00116996 TGFBR1 final crispr P24 U2OS 144 1286 Anaphase @@ -1069,6 +10609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.15265866209262435 4.085376186273856e-24 BR00116996 P2RY12 final crispr O21 U2OS 144 2332 Anaphase 0.1602271983903021 5.127424171376282e-24 BR00116997 TGFBR1 final crispr P24 U2OS 144 2106 Anaphase 0.16353955425811714 7.502092041037658e-24 BR00116996 OPRM1 final crispr P22 U2OS 144 2002 Anaphase +0.1590066676138173 9.881772625773106e-23 BR00116999 HIF1A final crispr M24 U2OS 144 2020 Anaphase +0.14365351629502573 2.153366266853769e-21 BR00116996 ABL1 final crispr P20 U2OS 144 2332 Anaphase +0.1541931326521219 3.746498306906303e-21 BR00116996 PTGIR final crispr G08 U2OS 144 1988 Anaphase +0.12681685718024052 8.131762710364502e-21 BR00116996 VEGFA final crispr C24 U2OS 144 2900 Anaphase +0.14486830154405086 1.4614775109490232e-20 BR00116999 TGFBR1 final crispr P24 U2OS 144 2202 Anaphase +0.13835972932047932 6.964681710918166e-20 BR00116996 HPGDS final crispr P14 U2OS 144 2330 Anaphase +0.15617977528089888 2.3593281218693575e-19 BR00116996 CHRM2 final crispr O22 U2OS 144 1780 Anaphase +0.13955824486008492 3.443716759148206e-19 BR00116996 FFAR4 final crispr G11 U2OS 144 2210 Anaphase +0.13952755240027045 5.810291990501094e-19 BR00116999 KDR final crispr J02 U2OS 144 2176 Anaphase +0.1614713216957606 1.1596956301137112e-18 BR00116996 SLCO2B1 final crispr A21 U2OS 144 1604 Anaphase +0.12496799076438962 6.174413826776504e-18 BR00116996 ALK final crispr I15 U2OS 144 2572 Anaphase +0.1267605633802817 2.5906488578578903e-17 BR00116996 CCR1 final crispr O17 U2OS 144 2414 Anaphase +0.2014626986537099 2.5797791190637407e-16 BR00116997 KCNN1 final crispr B24 U2OS 144 890 Anaphase +0.13377745979990852 3.1006051837171606e-16 BR00116996 KCNK1 final crispr N20 U2OS 144 2022 Anaphase +0.19436404298550997 4.197166246296542e-16 BR00116999 TUBB final crispr J17 U2OS 144 948 Anaphase +0.13883110023606515 7.293555215724707e-16 BR00116996 OPRM1 final crispr C23 U2OS 144 1828 Anaphase +0.14521757334257335 8.082164238441406e-16 BR00116999 CDK2 final crispr F08 U2OS 144 1664 Anaphase +0.11362079351767639 8.502810782424013e-16 BR00116999 RNASE1 final crispr K09 U2OS 144 2728 Anaphase +0.1426096997690531 9.023258731838615e-16 BR00116999 OPRL1 final crispr A04 U2OS 144 1732 Anaphase +0.140607424071991 9.736495122471009e-16 BR00116996 F10 final crispr H07 U2OS 144 1778 Anaphase +0.10984090624893426 9.76664899228205e-16 BR00116996 AKR1B1 final crispr L21 U2OS 144 2908 Anaphase +0.12972715153078976 2.5926381217426783e-15 BR00116996 CACNG1 final crispr N23 U2OS 144 2022 Anaphase +0.12088434047507188 2.6708101054018506e-15 BR00116996 PDE7A final crispr C22 U2OS 144 2328 Anaphase +0.16799826313504124 5.986785754808882e-15 BR00116998 CDC25A final crispr D06 U2OS 144 1176 Anaphase +0.12165775401069519 6.989399286096119e-15 BR00116996 RNASE1 final crispr K09 U2OS 144 2244 Anaphase +0.1836734693877551 7.384664428658983e-15 BR00116996 ADORA2A final crispr B22 U2OS 144 980 Anaphase +0.17900064842683908 1.0055138531885347e-14 BR00116998 GJB4 final crispr H01 U2OS 144 1018 Anaphase +0.16085578446909668 1.1576863107307998e-14 BR00116996 ICAM1 final crispr I12 U2OS 144 1262 Anaphase +0.12403155370836819 1.2502919004541679e-14 BR00116996 PTGIR final crispr G10 U2OS 144 2110 Anaphase +0.13585036347300497 1.383307965173786e-14 BR00116999 ADA final crispr O24 U2OS 144 1750 Anaphase +0.12147406733393995 1.5264656987614326e-14 BR00116999 PPAT final crispr G13 U2OS 144 2198 Anaphase +0.10165710643722116 1.5680439998103918e-14 BR00116999 HCK final crispr M23 U2OS 144 3138 Anaphase +0.12202275336603695 2.0646523470659606e-14 BR00116999 NAMPT final crispr I09 U2OS 144 2144 Anaphase +0.15772870662460567 3.539799499145588e-14 BR00116997 S1PR1 final crispr P23 U2OS 144 1268 Anaphase +0.1330984461308141 5.000730053507163e-14 BR00116996 PDE3A final crispr P18 U2OS 144 1760 Anaphase +0.13011538305600537 6.000339677866557e-14 BR00116996 PLD1 final crispr F11 U2OS 144 1832 Anaphase +0.15289164398582483 1.1566109239767285e-13 BR00116999 FGF1 final crispr J12 U2OS 144 1298 Anaphase +0.12333347957026985 1.5769463777430202e-13 BR00116996 DYRK1B final crispr K14 U2OS 144 1970 Anaphase +0.12088386440642038 2.0939069396193535e-13 BR00116996 FPR1 final crispr N22 U2OS 144 2038 Anaphase +0.12072336265884653 2.1013217006086188e-13 BR00116999 CDC25A final crispr D06 U2OS 144 2046 Anaphase +0.18959389349394717 2.1277885626042723e-13 BR00116999 TUBB3 final crispr K11 U2OS 144 820 Anaphase +0.10590832677974907 2.5542455391747754e-13 BR00116997 CACNA2D3 final crispr N24 U2OS 144 2630 Anaphase +0.14458689458689458 3.2642949711748717e-13 BR00116996 CACNA2D3 final crispr N24 U2OS 144 1404 Anaphase +0.11835291261357624 3.485824172792074e-13 BR00116999 ASIC1 final crispr J04 U2OS 144 2090 Anaphase +0.1285601942524332 4.587228537155332e-13 BR00116996 HDAC3 final crispr G07 U2OS 144 1754 Anaphase +0.09888149700615122 4.617220426849401e-13 BR00116999 CCR1 final crispr O17 U2OS 144 2968 Anaphase +0.10556511931792184 4.668458062628654e-13 BR00116999 TUBB4B final crispr C04 U2OS 144 2596 Anaphase +0.19029107498554262 5.105307181051562e-13 BR00116998 CDK2 final crispr F08 U2OS 144 788 Anaphase +0.1373992042888364 5.381246398869793e-13 BR00116996 PTGIS final crispr I16 U2OS 144 1518 Anaphase +0.14209930873623827 6.30823539195993e-13 BR00116997 GHSR final crispr B20 U2OS 144 1418 Anaphase +0.14101264629273869 7.095198153257831e-13 BR00116998 HSP90AB1 final crispr B04 U2OS 144 1428 Anaphase +0.11030981923645924 9.963767037002767e-13 BR00116996 GPR55 final crispr C21 U2OS 144 2308 Anaphase +0.11182935975998978 1.143263629793057e-12 BR00116996 PDPK1 final crispr N18 U2OS 144 2238 Anaphase +0.1075888687519716 1.2109181448274657e-12 BR00116996 PAK1 final crispr K10 U2OS 144 2412 Anaphase +0.11091722197541833 1.4889102780855456e-12 BR00116999 DNMT3A final crispr L04 U2OS 144 2250 Anaphase +0.12295973884657237 1.6038907749349813e-12 BR00116999 AGER final crispr K20 U2OS 144 1838 Anaphase +0.1251441753171857 3.017542305669485e-12 BR00116997 KCNK1 final crispr N20 U2OS 144 1734 Anaphase +0.09287216598121849 4.910388024887785e-12 BR00116999 KCNH7 final crispr O16 U2OS 144 3082 Anaphase +0.11974205243904704 4.956698362128678e-12 BR00116996 HTR3A final crispr O20 U2OS 144 1856 Anaphase +0.1145058389058844 5.072536898870282e-12 BR00116996 BTK final crispr D24 U2OS 144 2028 Anaphase +0.11639527750069077 5.08154092198524e-12 BR00116999 KCTD16 final crispr D08 U2OS 144 1962 Anaphase +0.11012569984532601 8.88165536701398e-12 BR00116997 TBXAS1 final crispr E24 U2OS 144 2140 Anaphase +0.12259884684388567 1.1733570887641265e-11 BR00116999 RGS4 final crispr N11 U2OS 144 1708 Anaphase +0.16454135110302318 1.2135570345989602e-11 BR00116999 CDK7 final crispr I14 U2OS 144 946 Anaphase +0.13431786216596342 1.3475250076565247e-11 BR00116998 CA5A final crispr M01 U2OS 144 1422 Anaphase +0.14496905198439503 1.469926334584483e-11 BR00116999 CDK9 final crispr I20 U2OS 144 1204 Anaphase +0.13143189433168112 1.485277738492216e-11 BR00116999 SIRT2 final crispr P01 U2OS 144 1470 Anaphase +0.12892646615894324 1.5550564298328042e-11 BR00116996 ATM final crispr F14 U2OS 144 1524 Anaphase +0.15775934654059443 1.6694141664930598e-11 BR00116998 SIRT2 final crispr P01 U2OS 144 1018 Anaphase +0.10974273895696898 2.368244089449735e-11 BR00116996 CHEK2 final crispr K03 U2OS 144 2082 Anaphase +0.10676653363532575 3.2734295119148276e-11 BR00116996 KCNMA1 final crispr E23 U2OS 144 2162 Anaphase +0.12931231437057344 3.8965833938205325e-11 BR00116996 PORCN final crispr L13 U2OS 144 1458 Anaphase +0.14144736842105263 5.0579209622641185e-11 BR00116996 S1PR1 final crispr A18 U2OS 144 1216 Anaphase +0.14226289517470883 5.063809457758559e-11 BR00116999 P3H1 final crispr I01 U2OS 144 1202 Anaphase +0.1199556933355982 5.453125297449143e-11 BR00116996 GABRB2 final crispr L22 U2OS 144 1682 Anaphase +0.127258997629523 7.402376076623867e-11 BR00116996 PIK3CG final crispr I08 U2OS 144 1466 Anaphase +0.1388113674776935 7.510805686881484e-11 BR00116998 GAA final crispr L17 U2OS 144 1236 Anaphase +0.10107689429261678 9.465214218331804e-11 BR00116996 HCK final crispr M23 U2OS 144 2316 Anaphase +0.1262580298801631 9.705191971062757e-11 BR00116999 PIK3CG final crispr I08 U2OS 144 1474 Anaphase +0.08790285526747621 1.0467803534537583e-10 BR00116999 HSP90AA1 final crispr C03 U2OS 144 3050 Anaphase +0.14221316259731864 1.1279286551255507e-10 BR00116998 BRD4 final crispr M19 U2OS 144 1158 Anaphase +0.1027525713303822 1.2126329720226904e-10 BR00116999 IMPDH1 final crispr G05 U2OS 144 2210 Anaphase +0.1121307079108497 1.3872451085109564e-10 BR00116999 DCK final crispr I07 U2OS 144 1842 Anaphase +0.13095886081505803 1.4859927049575283e-10 BR00116996 FGF1 final crispr J12 U2OS 144 1352 Anaphase +0.12254548192694634 1.7037523515874817e-10 BR00116996 DCK final crispr J08 U2OS 144 1538 Anaphase +0.10393070813690422 1.9523298168631852e-10 BR00116999 PTGIR final crispr G08 U2OS 144 2126 Anaphase +0.12349799732977303 2.2730392431489807e-10 BR00116996 P2RY12 final crispr P19 U2OS 144 1498 Anaphase +0.09682918003259518 2.4540747313688647e-10 BR00116999 CHEK2 final crispr M07 U2OS 144 2426 Anaphase +0.11019987280188662 2.6128972301886247e-10 BR00116996 CYP2A6 final crispr C07 U2OS 144 1856 Anaphase +0.18628252216218294 2.630592590045264e-10 BR00116998 TGFBR1 final crispr B08 U2OS 144 646 Anaphase 0.3783855864694188 3.950952218628893e-128 BR00116996 OPRM1 final crispr P22 U2OS 144 2002 Apoptosis 0.33919382504288165 2.892898048912436e-119 BR00116996 ABL1 final crispr P20 U2OS 144 2332 Apoptosis 0.3539325842696629 2.299884046244023e-99 BR00116996 CHRM2 final crispr O22 U2OS 144 1780 Apoptosis @@ -1079,6 +10709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2834476843910806 6.669632763579095e-83 BR00116996 P2RY12 final crispr O21 U2OS 144 2332 Apoptosis 0.3183258206863033 4.053783484601205e-74 BR00116996 GRIN2A final crispr A23 U2OS 144 1642 Apoptosis 0.29972216032533006 5.5930104455007276e-74 BR00116996 HTR3A final crispr O20 U2OS 144 1856 Apoptosis +0.32506527415143605 5.332584174737558e-72 BR00116996 S1PR1 final crispr P23 U2OS 144 1532 Apoptosis +0.23301555896543197 4.0183263392243324e-71 BR00116996 IGF1R final crispr M22 U2OS 144 2964 Apoptosis +0.27560542139217414 1.0162509678795027e-68 BR00116996 FPR1 final crispr N22 U2OS 144 2038 Apoptosis +0.3210947930574099 1.112781407942517e-68 BR00116996 P2RY12 final crispr P19 U2OS 144 1498 Apoptosis +0.27774124816303947 1.1316445426567639e-62 BR00116996 OPRM1 final crispr C23 U2OS 144 1828 Apoptosis +0.21539317957440735 1.8938750181618707e-59 BR00116996 VEGFA final crispr C24 U2OS 144 2900 Apoptosis +0.24062814237038993 2.939209161767426e-59 BR00116996 HCK final crispr M23 U2OS 144 2316 Apoptosis +0.28615960099750626 2.957930534293138e-58 BR00116996 SLCO2B1 final crispr A21 U2OS 144 1604 Apoptosis +0.23647828901623227 1.1435387136279662e-57 BR00116996 HPGDS final crispr P14 U2OS 144 2330 Apoptosis +0.31774960380348655 1.0385397970943632e-56 BR00116996 ICAM1 final crispr I12 U2OS 144 1262 Apoptosis +0.371707224950089 1.5695724141036407e-53 BR00116996 ADA final crispr O24 U2OS 144 862 Apoptosis +0.24123035932802414 3.760778828694154e-52 BR00116996 CACNG1 final crispr N23 U2OS 144 2022 Apoptosis +0.19827037411756682 1.7393082714370012e-50 BR00116996 AKR1B1 final crispr L21 U2OS 144 2908 Apoptosis +0.24885259479351787 9.062153398604337e-49 BR00116996 HIF1A final crispr M24 U2OS 144 1772 Apoptosis +0.25879396984924624 3.0130054940494464e-47 BR00116996 HSD11B1 final crispr O23 U2OS 144 1592 Apoptosis +0.3637981060485285 3.369978315341681e-47 BR00116996 FFAR2 final crispr A24 U2OS 144 794 Apoptosis +0.2727920227920228 2.3056771622624376e-46 BR00116996 CACNA2D3 final crispr N24 U2OS 144 1404 Apoptosis +0.2810337666145426 4.0412920935316724e-45 BR00116996 GPR119 final crispr P21 U2OS 144 1280 Apoptosis +0.20256835128417564 9.807052929141878e-44 BR00116996 CCR1 final crispr O17 U2OS 144 2414 Apoptosis +0.218069674359816 1.1872599150231436e-42 BR00116999 HIF1A final crispr M24 U2OS 144 2020 Apoptosis +0.28544654434622074 2.6671511503012447e-41 BR00116996 KCNH7 final crispr P16 U2OS 144 1134 Apoptosis +0.20434954495082847 7.192877637636842e-41 BR00116996 FFAR4 final crispr G11 U2OS 144 2210 Apoptosis +0.2072177874274128 3.5096122721564154e-40 BR00116996 PTGIR final crispr G10 U2OS 144 2110 Apoptosis +0.18270863846581192 7.009083648064871e-39 BR00116997 CACNA2D3 final crispr N24 U2OS 144 2630 Apoptosis +0.18345998800145533 2.59717332687317e-38 BR00116996 ALK final crispr I15 U2OS 144 2572 Apoptosis +0.21122994652406418 6.32165490230441e-37 BR00116999 S1PR1 final crispr P23 U2OS 144 1870 Apoptosis +0.2782161386077566 9.975491103924617e-37 BR00116996 CHRM3 final crispr B21 U2OS 144 1066 Apoptosis +0.23313141707790538 1.1493614585092351e-36 BR00116996 PTGIS final crispr I16 U2OS 144 1518 Apoptosis +0.15386819484240688 1.8999021730275546e-36 BR00116999 PDE3A final crispr P18 U2OS 144 3490 Apoptosis +0.20257736081064767 5.3943809881952225e-36 BR00116996 SLCO2B1 final crispr I24 U2OS 144 1982 Apoptosis +0.21743435837211664 5.975483893634596e-35 BR00116999 ADH1C final crispr P04 U2OS 144 1660 Apoptosis +0.23903177004538578 1.5489486627162655e-33 BR00116996 BTK final crispr P17 U2OS 144 1322 Apoptosis +0.17666643028309886 3.013695638163401e-32 BR00116996 PDE7A final crispr C22 U2OS 144 2328 Apoptosis +0.18872002830524312 6.210115222493954e-32 BR00116996 KCNK1 final crispr N20 U2OS 144 2022 Apoptosis +0.19092694432759827 6.963855997605364e-32 BR00116996 DYRK1B final crispr K14 U2OS 144 1970 Apoptosis +0.14775232633387633 9.786039586842101e-32 BR00116996 CYP1A2 final crispr K22 U2OS 144 3280 Apoptosis +0.19738718670924568 1.0342147248919662e-31 BR00116996 PLD1 final crispr F11 U2OS 144 1832 Apoptosis +0.17390881735474104 6.258822285320239e-31 BR00116996 GPR55 final crispr C21 U2OS 144 2308 Apoptosis +0.17606879548065876 7.689764561212132e-31 BR00116996 PDPK1 final crispr N18 U2OS 144 2238 Apoptosis +0.15491009681881052 1.1083308918814437e-30 BR00116996 ASIC1 final crispr M20 U2OS 144 2892 Apoptosis +0.18756423432682426 2.5105140210562273e-30 BR00116996 ELANE final crispr N19 U2OS 144 1946 Apoptosis +0.29548620785734186 2.5147923594567547e-30 BR00116996 CCND1 final crispr B23 U2OS 144 776 Apoptosis +0.2138153520237401 6.433927288967943e-30 BR00116996 PIK3CG final crispr I08 U2OS 144 1466 Apoptosis +0.191512513601741 7.090292513709985e-30 BR00116999 AGER final crispr K20 U2OS 144 1838 Apoptosis +0.25918367346938775 2.4908038303008712e-29 BR00116996 ADORA2A final crispr B22 U2OS 144 980 Apoptosis +0.20515200761679636 2.740952866331665e-29 BR00116996 RET final crispr I03 U2OS 144 1562 Apoptosis +0.21864879685011857 2.743431555834543e-29 BR00116996 SLC29A1 final crispr N21 U2OS 144 1378 Apoptosis +0.262988355497459 2.877478175131591e-29 BR00116999 TUBB final crispr J17 U2OS 144 948 Apoptosis +0.21326594549747296 3.964559644448467e-29 BR00116996 ADRA2B final crispr J14 U2OS 144 1442 Apoptosis +0.17698992900867416 6.671176102034759e-29 BR00116996 CHEK2 final crispr K03 U2OS 144 2082 Apoptosis +0.14133253416893632 2.100654019171065e-28 BR00116998 ALDH2 final crispr A10 U2OS 144 3212 Apoptosis +0.20488829912864126 7.831454001514937e-28 BR00116996 SCNN1G final crispr P15 U2OS 144 1492 Apoptosis +0.20699455277492698 2.3447006595463176e-27 BR00116996 S1PR2 final crispr J23 U2OS 144 1434 Apoptosis +0.20465752986759256 3.3159068947186334e-27 BR00116996 PORCN final crispr L13 U2OS 144 1458 Apoptosis +0.2256560436906622 9.61789113482302e-27 BR00116999 CTSG final crispr G18 U2OS 144 1172 Apoptosis +0.14829188204943852 2.316789164661109e-26 BR00116997 UGT1A9 final crispr B18 U2OS 144 2694 Apoptosis +0.17224968716269462 2.924386243380858e-26 BR00116996 PTGIR final crispr G08 U2OS 144 1988 Apoptosis +0.1639418710263397 3.0739484118774346e-26 BR00116999 TGFBR1 final crispr P24 U2OS 144 2202 Apoptosis +0.16729421258146357 5.160425421865821e-26 BR00116996 PDE4D final crispr J24 U2OS 144 2094 Apoptosis +0.2072609072648288 6.499020832410865e-26 BR00116996 ITGB2 final crispr A17 U2OS 144 1356 Apoptosis +0.16956077630234934 5.5029181643578195e-25 BR00116996 KCNQ2 final crispr P13 U2OS 144 1958 Apoptosis +0.14433872847194731 8.000100158301523e-25 BR00116996 HDAC6 final crispr K12 U2OS 144 2680 Apoptosis +0.18289226726726726 9.394449385396596e-25 BR00116999 CDK2 final crispr F08 U2OS 144 1664 Apoptosis +0.1749156355455568 3.636843850003213e-24 BR00116996 F10 final crispr H07 U2OS 144 1778 Apoptosis +0.31800766283524906 9.888400092476704e-24 BR00116996 PLA2G1B final crispr J11 U2OS 144 522 Apoptosis +0.18653433847430667 1.3908044409303137e-23 BR00116996 TNNC1 final crispr D09 U2OS 144 1520 Apoptosis +0.17315161303541543 1.688281584203518e-23 BR00116996 HDAC3 final crispr G07 U2OS 144 1754 Apoptosis +0.19856934319744238 2.1713334256691833e-23 BR00116996 RNASE1 final crispr I13 U2OS 144 1332 Apoptosis +0.1984233619549472 4.5248272648810845e-23 BR00116996 TBXAS1 final crispr E24 U2OS 144 1308 Apoptosis +0.17193291044201958 6.014881964273553e-23 BR00116999 S1PR2 final crispr K02 U2OS 144 1736 Apoptosis +0.18187525223084167 9.105003255032999e-23 BR00116996 DCK final crispr J08 U2OS 144 1538 Apoptosis +0.16718416860014068 9.966026056852467e-23 BR00116999 FPR1 final crispr I18 U2OS 144 1822 Apoptosis +0.20797962648556875 1.0442082100734544e-22 BR00116996 PPAT final crispr G13 U2OS 144 1178 Apoptosis +0.16554497892410822 1.2165301029344678e-22 BR00116996 CYP2A6 final crispr C07 U2OS 144 1856 Apoptosis +0.12276519666269368 1.9165546915904203e-22 BR00116996 PNLIP final crispr C18 U2OS 144 3356 Apoptosis +0.14177316293929712 2.3648776153805926e-22 BR00116997 HSD11B1 final crispr O23 U2OS 144 2504 Apoptosis +0.22379032258064516 3.564483301711363e-22 BR00116996 FOXM1 final crispr A19 U2OS 144 992 Apoptosis +0.1477364134458759 7.109436975085628e-22 BR00116999 DNMT3A final crispr L04 U2OS 144 2250 Apoptosis +0.20364925631269457 7.52165417785118e-22 BR00116999 PTGIR final crispr G10 U2OS 144 1180 Apoptosis +0.19903467647815165 8.174041575164076e-22 BR00116996 ERBB2 final crispr I11 U2OS 144 1230 Apoptosis +0.2803825294438561 1.2994892360158515e-21 BR00116999 PLK1 final crispr G09 U2OS 144 612 Apoptosis +0.1671182872306787 1.5367776880484723e-21 BR00116998 PDE4D final crispr P06 U2OS 144 1732 Apoptosis +0.1910313527917725 1.6206752383091855e-21 BR00116996 GLRA3 final crispr F16 U2OS 144 1314 Apoptosis +0.10013560749631502 3.2323127870564123e-21 BR00116998 TNF final crispr I10 U2OS 144 4750 Apoptosis +0.1750706533618073 5.589016024530596e-21 BR00116998 CDC25A final crispr C14 U2OS 144 1534 Apoptosis +0.11913357400722022 5.84421047431882e-21 BR00116997 HDAC6 final crispr L10 U2OS 144 3324 Apoptosis +0.14695009242144177 8.658698512555664e-21 BR00116996 SCNN1G final crispr G24 U2OS 144 2164 Apoptosis +0.16612168053904083 9.090807945359612e-21 BR00116996 GABRB2 final crispr L22 U2OS 144 1682 Apoptosis +0.1724137931034483 9.751018262113916e-21 BR00116999 ATM final crispr G12 U2OS 144 1566 Apoptosis +0.19490131578947367 1.3173417710678543e-20 BR00116996 S1PR1 final crispr A18 U2OS 144 1216 Apoptosis 0.4092352417425632 2.4847281783855632e-145 BR00116999 CACNA2D3 final crispr N24 U2OS 144 1932 Binuclear 0.3862948428816692 1.0017474014087736e-133 BR00116996 OPRM1 final crispr P22 U2OS 144 2002 Binuclear 0.4665629860031104 8.553146485180227e-127 BR00116996 TGFBR1 final crispr P24 U2OS 144 1286 Binuclear @@ -1089,6 +10809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2637221269296741 1.0933590770208333e-71 BR00116996 P2RY12 final crispr O21 U2OS 144 2332 Binuclear 0.3090046557666604 9.512986590176543e-70 BR00116996 GRIN2A final crispr A23 U2OS 144 1642 Binuclear 0.3210947930574099 1.112781407942517e-68 BR00116996 P2RY12 final crispr P19 U2OS 144 1498 Binuclear +0.27828500046111154 6.409753710986156e-63 BR00116996 OPRM1 final crispr C23 U2OS 144 1828 Binuclear +0.29301745635910226 4.20303627305045e-61 BR00116996 SLCO2B1 final crispr A21 U2OS 144 1604 Binuclear +0.21546236238848634 9.014185150643625e-61 BR00116996 IGF1R final crispr M22 U2OS 144 2964 Binuclear +0.2684773828756058 2.910574031576097e-59 BR00116996 HTR3A final crispr O20 U2OS 144 1856 Binuclear +0.306980056980057 8.3825572831246e-59 BR00116996 CACNA2D3 final crispr N24 U2OS 144 1404 Binuclear +0.2864321608040201 6.205859861950995e-58 BR00116996 HSD11B1 final crispr O23 U2OS 144 1592 Binuclear +0.24963279002783118 6.380295859391471e-56 BR00116996 BTK final crispr D24 U2OS 144 2028 Binuclear +0.39188853107164495 7.046038193407208e-55 BR00116996 FFAR2 final crispr A24 U2OS 144 794 Binuclear +0.24474406984043479 3.8677810654339774e-54 BR00116996 FPR1 final crispr N22 U2OS 144 2038 Binuclear +0.25812710950431333 1.899851377515834e-52 BR00116996 HIF1A final crispr M24 U2OS 144 1772 Binuclear +0.2238120582046196 2.904497861785434e-51 BR00116996 HCK final crispr M23 U2OS 144 2316 Binuclear +0.2228063542183474 3.552113894484509e-51 BR00116996 HPGDS final crispr P14 U2OS 144 2330 Binuclear +0.3554065720606486 8.101354244141629e-49 BR00116996 ADA final crispr O24 U2OS 144 862 Binuclear +0.24171122994652405 2.470295561028225e-48 BR00116999 S1PR1 final crispr P23 U2OS 144 1870 Binuclear +0.22281875652408487 1.8940131434053117e-44 BR00116996 CACNG1 final crispr N23 U2OS 144 2022 Binuclear +0.2951148096779165 4.522006172555498e-44 BR00116996 KCNH7 final crispr P16 U2OS 144 1134 Binuclear +0.27555829749804533 2.2399749773710107e-43 BR00116996 GPR119 final crispr P21 U2OS 144 1280 Binuclear +0.17539317957440734 1.725988923934447e-39 BR00116996 VEGFA final crispr C24 U2OS 144 2900 Binuclear +0.20861155883030164 5.754336814408201e-39 BR00116999 HIF1A final crispr M24 U2OS 144 2020 Binuclear +0.1980018165304269 3.704186171374142e-38 BR00116999 TGFBR1 final crispr P24 U2OS 144 2202 Binuclear +0.20324006416150198 2.372284932837976e-36 BR00116996 SLCO2B1 final crispr I24 U2OS 144 1982 Binuclear +0.2670648028257097 5.083453456932668e-34 BR00116996 CHRM3 final crispr B21 U2OS 144 1066 Binuclear +0.17966480810086488 2.467356387444711e-33 BR00116996 PDE7A final crispr C22 U2OS 144 2328 Binuclear +0.18772406688482032 1.3314380226133649e-31 BR00116996 KCNK1 final crispr N20 U2OS 144 2022 Binuclear +0.17149958574979288 2.0858435319880754e-31 BR00116996 CCR1 final crispr O17 U2OS 144 2414 Binuclear +0.32348366330402256 2.4684298120103047e-31 BR00116996 MAPK14 final crispr A20 U2OS 144 666 Binuclear +0.26632653061224487 5.771057862158951e-31 BR00116996 ADORA2A final crispr B22 U2OS 144 980 Binuclear +0.27138880453487196 2.210274619099611e-29 BR00116997 KCNN1 final crispr B24 U2OS 144 890 Binuclear +0.22712933753943218 4.513099975052142e-29 BR00116997 S1PR1 final crispr P23 U2OS 144 1268 Binuclear +0.15014531964638256 4.59521837142127e-29 BR00116996 AKR1B1 final crispr L21 U2OS 144 2908 Binuclear +0.376797598303697 4.697197291003271e-28 BR00116996 KCNN4 final crispr A22 U2OS 144 436 Binuclear +0.2140695915279879 6.254506722718089e-27 BR00116996 BTK final crispr P17 U2OS 144 1322 Binuclear +0.16789536963725404 2.1735720272633845e-26 BR00116997 TGFBR1 final crispr P24 U2OS 144 2106 Binuclear +0.21356118305244262 7.208991671975719e-26 BR00116996 KDR final crispr O18 U2OS 144 1268 Binuclear +0.20074900981686514 2.2072628946272335e-24 BR00116996 ITGB2 final crispr A17 U2OS 144 1356 Binuclear +0.3036967300571142 2.0663375377714594e-23 BR00116996 KCNN1 final crispr B24 U2OS 144 564 Binuclear +0.1338174273858921 5.57680204476217e-23 BR00116996 ASIC1 final crispr M20 U2OS 144 2892 Binuclear +0.1495977236238575 5.813156994486945e-23 BR00116996 GPR55 final crispr C21 U2OS 144 2308 Binuclear +0.20476973684210525 1.0215568795604563e-22 BR00116996 S1PR1 final crispr A18 U2OS 144 1216 Binuclear +0.13753869019704043 3.5892198541278536e-22 BR00116997 CACNA2D3 final crispr N24 U2OS 144 2630 Binuclear +0.18968436983952738 3.8400961300081453e-22 BR00116996 SLC29A1 final crispr N21 U2OS 144 1378 Binuclear +0.25154904536347833 5.094672158282721e-22 BR00116996 CCND1 final crispr B23 U2OS 144 776 Binuclear +0.15346996646857824 5.952359340011902e-22 BR00116996 PDE4D final crispr J24 U2OS 144 2094 Binuclear +0.18299226043759081 1.9916779813605602e-21 BR00116996 S1PR2 final crispr J23 U2OS 144 1434 Binuclear +0.2157258064516129 1.2692656827188988e-20 BR00116996 FOXM1 final crispr A19 U2OS 144 992 Binuclear +0.14417744916820702 5.0270334247893406e-20 BR00116996 SCNN1G final crispr G24 U2OS 144 2164 Binuclear +0.20799180327868852 6.90476480401443e-19 BR00116996 HRH4 final crispr H24 U2OS 144 976 Binuclear +0.13539873658039392 8.78456268180645e-18 BR00116996 KCNMA1 final crispr E23 U2OS 144 2162 Binuclear +0.17189835575485798 1.1257114693058413e-17 BR00116996 SIRT2 final crispr O19 U2OS 144 1338 Binuclear +0.17216005710326873 2.03158361492188e-17 BR00116996 TBXAS1 final crispr E24 U2OS 144 1308 Binuclear +0.16098140993165072 2.4673253157900817e-17 BR00116996 SCNN1G final crispr P15 U2OS 144 1492 Binuclear +0.14735658042744657 3.003253846049679e-17 BR00116996 F10 final crispr H07 U2OS 144 1778 Binuclear +0.10720884564746837 6.641715691326268e-17 BR00116996 CYP1A2 final crispr K22 U2OS 144 3280 Binuclear +0.13010207112409333 9.69987251836339e-17 BR00116996 FFAR4 final crispr G11 U2OS 144 2210 Binuclear +0.1666805457245562 1.802870778885315e-16 BR00116996 GLRA3 final crispr F16 U2OS 144 1314 Binuclear +0.10257879656160458 2.1210530585262514e-16 BR00116999 PDE3A final crispr P18 U2OS 144 3490 Binuclear +0.12289562289562289 4.786086020561922e-16 BR00116996 CATSPER4 final crispr P02 U2OS 144 2376 Binuclear +0.12500598429720414 1.0975719010270508e-15 BR00116996 PDPK1 final crispr N18 U2OS 144 2238 Binuclear +0.14088377031773258 1.3586275081528855e-15 BR00116999 ADA final crispr O24 U2OS 144 1750 Binuclear +0.13309352517985612 1.9486511849762537e-15 BR00116996 ELANE final crispr N19 U2OS 144 1946 Binuclear +0.15272218884535793 2.3622153265218456e-15 BR00116996 PORCN final crispr L13 U2OS 144 1458 Binuclear +0.16085578446909668 1.1576863107307998e-14 BR00116996 ICAM1 final crispr I12 U2OS 144 1262 Binuclear +0.17020640569395018 1.17414052344949e-14 BR00116996 ITGB2 final crispr D23 U2OS 144 1124 Binuclear +0.1382955381914954 1.715595981544682e-14 BR00116996 GABRB2 final crispr L22 U2OS 144 1682 Binuclear +0.13610149942329874 2.0520235215511024e-14 BR00116997 KCNK1 final crispr N20 U2OS 144 1734 Binuclear +0.09624553039332538 6.040649256671768e-14 BR00116996 PNLIP final crispr C18 U2OS 144 3356 Binuclear +0.12910476771945556 9.55539242690727e-14 BR00116996 PLD1 final crispr F11 U2OS 144 1832 Binuclear +0.1657919110836678 1.008132855548251e-13 BR00116996 OPRL1 final crispr A11 U2OS 144 1106 Binuclear +0.19355588186093195 1.1394808706959132e-13 BR00116996 HPGDS final crispr B19 U2OS 144 804 Binuclear +0.12202374629880844 2.1055635589404953e-13 BR00116996 PTGIR final crispr G08 U2OS 144 1988 Binuclear +0.12754665677913732 3.1572385371185314e-13 BR00116996 FOXM1 final crispr F23 U2OS 144 1800 Binuclear +0.14665867971653096 6.228456008473265e-13 BR00116996 RNASE1 final crispr I13 U2OS 144 1332 Binuclear +0.12104187946884576 6.532197009771375e-13 BR00116996 KCNQ2 final crispr P13 U2OS 144 1958 Binuclear +0.15259182742614902 6.610785075019237e-13 BR00116997 GRIN2A final crispr A23 U2OS 144 1222 Binuclear +0.12097611630321911 1.0778227430661186e-12 BR00116996 ATP5F1D final crispr G21 U2OS 144 1926 Binuclear +0.18355985037406483 2.7314437086862107e-12 BR00116996 KCNMA1 final crispr A07 U2OS 144 802 Binuclear +0.10917312711010282 2.7499836934414498e-12 BR00116996 CYP3A4 final crispr D20 U2OS 144 2284 Binuclear +0.1915457860384303 3.8681287232328765e-12 BR00116998 FFAR2 final crispr A24 U2OS 144 726 Binuclear +0.1436251920122888 3.989108791555499e-12 BR00116997 BTK final crispr D24 U2OS 144 1302 Binuclear +0.13383485431475864 4.483437226890572e-12 BR00116996 KCNQ2 final crispr A16 U2OS 144 1484 Binuclear +0.11554145946183086 6.6436170292668e-12 BR00116996 DYRK1B final crispr K14 U2OS 144 1970 Binuclear +0.13069724775410393 8.628938223898714e-12 BR00116996 PTGIS final crispr I16 U2OS 144 1518 Binuclear +0.14642998138852856 1.2543031517218155e-11 BR00116996 ANXA1 final crispr F24 U2OS 144 1190 Binuclear +0.0966124129343983 2.229307094387553e-11 BR00116997 UGT1A9 final crispr B18 U2OS 144 2694 Binuclear +0.09525364886115494 2.5096460453474414e-11 BR00116996 TNNC1 final crispr L09 U2OS 144 2756 Binuclear +0.11550945745160375 3.945210053061753e-11 BR00116996 CA14 final crispr C19 U2OS 144 1832 Binuclear +0.1251596424010217 4.194333711321451e-11 BR00116999 ATM final crispr G12 U2OS 144 1566 Binuclear +0.11991032408195698 5.311215294021322e-11 BR00116996 JAK1 final crispr M21 U2OS 144 1680 Binuclear +0.08571428571428572 6.19756389635721e-11 BR00116998 HIF1A final crispr A01 U2OS 144 3290 Binuclear +0.0971451229183188 8.91906768361154e-11 BR00116998 CCR1 final crispr O17 U2OS 144 2522 Binuclear 0.187402799377916 3.782939174302413e-20 BR00116996 TGFBR1 final crispr P24 U2OS 144 1286 Elongated 0.13379073756432247 1.323878966405165e-18 BR00116996 ABL1 final crispr P20 U2OS 144 2332 Elongated 0.1384498734798136 3.123184001362473e-17 BR00116996 OPRM1 final crispr P22 U2OS 144 2002 Elongated @@ -1099,6 +10909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.12962998812658097 2.444711802356407e-13 BR00116996 PDE3A final crispr P18 U2OS 144 1760 Elongated 0.2141641894292071 8.044763619067255e-12 BR00116999 SLC7A11 final crispr P05 U2OS 144 566 Elongated 0.12022471910112359 1.2692569363414253e-11 BR00116996 CHRM2 final crispr O22 U2OS 144 1780 Elongated +0.14195583596214512 1.481701121510618e-11 BR00116997 S1PR1 final crispr P23 U2OS 144 1268 Elongated +0.11733609819140314 2.5649755553128325e-11 BR00116999 LCK final crispr O15 U2OS 144 1812 Elongated +0.13048667742959252 4.855849407326896e-11 BR00116997 ICAM1 final crispr I12 U2OS 144 1428 Elongated +0.10259099350484073 8.509305646475435e-11 BR00116999 ALK final crispr I15 U2OS 144 2256 Elongated +0.11063731642690867 9.60713833232438e-11 BR00116999 CACNA2D3 final crispr N24 U2OS 144 1932 Elongated +0.13843648208469056 1.1260498270860274e-10 BR00116997 PDPK1 final crispr E16 U2OS 144 1228 Elongated +0.11168552147853093 8.251219964668362e-10 BR00116996 PDE7A final crispr C10 U2OS 144 1718 Elongated +0.14766263785291356 1.8507991406035264e-09 BR00116996 CDK7 final crispr I14 U2OS 144 942 Elongated +0.10510767132943902 1.9861691998725932e-09 BR00116997 PDE4D final crispr P06 U2OS 144 1860 Elongated +0.1527815248475692 3.041561989434545e-09 BR00116996 ADA final crispr O24 U2OS 144 862 Elongated +0.10202855641017389 3.2601497384680394e-09 BR00116999 JAK1 final crispr M21 U2OS 144 1932 Elongated +0.10176531671858775 4.225105860928713e-09 BR00116996 ATP5F1D final crispr G21 U2OS 144 1926 Elongated +0.12118020629054368 5.453507350904285e-09 BR00116998 LCK final crispr O15 U2OS 144 1334 Elongated +0.09569025501861322 5.465955688150472e-09 BR00116999 NAMPT final crispr I09 U2OS 144 2144 Elongated +0.11149426224163787 5.9342158587652795e-09 BR00116997 ADA final crispr O24 U2OS 144 1568 Elongated +0.10813796703057718 6.535945865225362e-09 BR00116999 P2RY12 final crispr P19 U2OS 144 1660 Elongated +0.1288219879697457 7.129424848708303e-09 BR00116998 S1PR1 final crispr P23 U2OS 144 1160 Elongated +0.11188685579258058 1.054399146656556e-08 BR00116997 PDE4D final crispr J24 U2OS 144 1514 Elongated +0.09211919393378187 1.1884196884755141e-08 BR00116998 HTR2C final crispr M12 U2OS 144 2224 Elongated +0.09619686148480174 1.2810849823994544e-08 BR00116996 BTK final crispr D24 U2OS 144 2028 Elongated +0.09970951014799546 1.738462178075504e-08 BR00116996 HTR3A final crispr O20 U2OS 144 1856 Elongated +0.101286418161951 3.627296600355629e-08 BR00116998 PDE4D final crispr P06 U2OS 144 1732 Elongated +0.1081441922563418 4.787652053060596e-08 BR00116996 P2RY12 final crispr P19 U2OS 144 1498 Elongated +0.1100837250366464 5.854304796382991e-08 BR00116999 GRIN2A final crispr A23 U2OS 144 1422 Elongated +0.08619210977701544 5.879235529547e-08 BR00116996 P2RY12 final crispr O21 U2OS 144 2332 Elongated +0.10427135678391959 5.922418451811226e-08 BR00116996 EZH2 final crispr C05 U2OS 144 1592 Elongated +0.11399006357665535 6.18786673268171e-08 BR00116997 ABL1 final crispr P20 U2OS 144 1322 Elongated +0.09100115740740741 7.617030201964826e-08 BR00116998 ADH1C final crispr P04 U2OS 144 2052 Elongated +0.10657259869675516 9.472850324363643e-08 BR00116998 HPGDS final crispr P14 U2OS 144 1476 Elongated +0.08906934829341796 9.815427819063485e-08 BR00116997 TGFBR1 final crispr P24 U2OS 144 2106 Elongated +0.12743190661478598 1.083687479240056e-07 BR00116998 ERBB2 final crispr I11 U2OS 144 1028 Elongated +0.094610504479968 1.3760987709560114e-07 BR00116996 OPRM1 final crispr C23 U2OS 144 1828 Elongated +0.0848059706088389 1.4446161970770588e-07 BR00116998 SCNN1G final crispr G24 U2OS 144 2280 Elongated +0.0964770072694601 1.445334012663853e-07 BR00116999 ADA final crispr O24 U2OS 144 1750 Elongated +0.1183827224735042 1.475804228391587e-07 BR00116998 PDPK1 final crispr E16 U2OS 144 1162 Elongated +0.11356466876971609 1.5358521241817414e-07 BR00116997 EZH2 final crispr H09 U2OS 144 1268 Elongated +0.1298962542707023 1.9508011938233718e-07 BR00116998 BRD4 final crispr J16 U2OS 144 948 Elongated +0.12264150943396226 2.3053029829857825e-07 BR00116999 TNF final crispr N17 U2OS 144 1060 Elongated +0.14949068772225907 2.441379895995963e-07 BR00116997 CDK2 final crispr L19 U2OS 144 706 Elongated +0.10664799497652523 2.5314364976195066e-07 BR00116997 GABRB2 final crispr L22 U2OS 144 1386 Elongated +0.07669897545930604 2.80053164360239e-07 BR00116997 HRH4 final crispr A08 U2OS 144 2664 Elongated +0.06909025654757919 2.8441630223812413e-07 BR00116996 CYP1A2 final crispr K22 U2OS 144 3280 Elongated +0.0937071673049962 3.79041815744798e-07 BR00116996 PDE4D final crispr P06 U2OS 144 1752 Elongated +0.07622641509433963 4.061182626831898e-07 BR00116999 CSK final crispr B11 U2OS 144 2650 Elongated +0.09638414964837255 4.0904889330699553e-07 BR00116996 GRIN2A final crispr A23 U2OS 144 1642 Elongated +0.09682188991034708 5.008588203145627e-07 BR00116997 HPGDS final crispr P14 U2OS 144 1606 Elongated +0.107290380724837 5.265527407995697e-07 BR00116998 LCK final crispr O13 U2OS 144 1304 Elongated +0.07351977289232191 6.365185903914734e-07 BR00116999 CSK final crispr B05 U2OS 144 2754 Elongated +0.0957972805933251 6.989983199714891e-07 BR00116997 P2RY12 final crispr O21 U2OS 144 1618 Elongated +0.09765089797595021 7.556062159009262e-07 BR00116998 CDC25A final crispr C14 U2OS 144 1534 Elongated +0.08741817437701503 7.946582720067298e-07 BR00116999 SSTR2 final crispr P10 U2OS 144 1916 Elongated +0.13156993253477303 8.093297114200937e-07 BR00116998 MAPK8 final crispr D13 U2OS 144 842 Elongated +0.10947712418300654 8.313578847073418e-07 BR00116996 MAPK8 final crispr D13 U2OS 144 1224 Elongated +0.0906275905166367 8.665689051765501e-07 BR00116996 S100B final crispr C09 U2OS 144 1770 Elongated +0.10113960113960115 1.1358580101862546e-06 BR00116996 CACNA2D3 final crispr N24 U2OS 144 1404 Elongated +0.09566326530612244 1.1523424460222191e-06 BR00116998 CLK1 final crispr M11 U2OS 144 1568 Elongated +0.09660574412532637 1.2133342921607014e-06 BR00116996 S1PR1 final crispr P23 U2OS 144 1532 Elongated +0.07009668508287292 1.309725091225339e-06 BR00116999 FFAR2 final crispr A06 U2OS 144 2896 Elongated +0.1041050309233607 1.532482969097675e-06 BR00116999 HTR3A final crispr O20 U2OS 144 1290 Elongated +0.11987704918032786 1.5785248110689683e-06 BR00116996 HRH4 final crispr H24 U2OS 144 976 Elongated +0.10265036382057659 1.6467079291198326e-06 BR00116998 ADA final crispr O24 U2OS 144 1316 Elongated +0.080453389052569 1.7476412950758992e-06 BR00116996 LCK final crispr O15 U2OS 144 2140 Elongated +0.08844760000102954 1.8768209573364854e-06 BR00116997 CDC25A final crispr C14 U2OS 144 1762 Elongated +0.08278979651329971 1.9998618289098423e-06 BR00116999 ICAM1 final crispr I12 U2OS 144 2008 Elongated +0.09005630224754094 2.0897421257441382e-06 BR00116996 GABRB2 final crispr D10 U2OS 144 1690 Elongated +0.0857449088960343 2.1734172220051837e-06 BR00116998 PTGIS final crispr K17 U2OS 144 1866 Elongated +0.06407185628742515 2.203264984215482e-06 BR00116999 ANXA1 final crispr G01 U2OS 144 3340 Elongated +0.08321902816284839 2.3260305188608987e-06 BR00116999 ADA final crispr O06 U2OS 144 1960 Elongated +0.09581646423751687 2.426463031971456e-06 BR00116999 NTRK1 final crispr P07 U2OS 144 1482 Elongated +0.09331315696106217 2.8040067928492596e-06 BR00116998 CDK7 final crispr E12 U2OS 144 1530 Elongated +0.11632653061224489 3.4013479089423924e-06 BR00116996 ADORA2A final crispr B22 U2OS 144 980 Elongated +0.1546363447643155 3.483833660739678e-06 BR00116998 KCNN4 final crispr A22 U2OS 144 546 Elongated +0.08174091756130543 3.5057470346019324e-06 BR00116999 CA14 final crispr C19 U2OS 144 1972 Elongated +0.18742655699177438 3.5063288816449926e-06 BR00116997 RPL3 final crispr K04 U2OS 144 370 Elongated +0.07455770850884583 3.6783946572669947e-06 BR00116999 TGM2 final crispr O03 U2OS 144 2374 Elongated +0.10221870047543581 3.686347895595615e-06 BR00116999 NTRK1 final crispr O10 U2OS 144 1262 Elongated +0.07521170613932864 3.8010289500421893e-06 BR00116996 PTK2B final crispr M06 U2OS 144 2312 Elongated +0.0990237258388142 4.146278659641697e-06 BR00116999 TBXAS1 final crispr P08 U2OS 144 1322 Elongated +0.06472480877951446 4.23802272742942e-06 BR00116997 AKR1C1 final crispr B06 U2OS 144 3100 Elongated +0.09513888888888888 4.303552994081316e-06 BR00116998 FOXM1 final crispr A19 U2OS 144 1440 Elongated +0.08360651536226617 4.375883048254777e-06 BR00116996 BRD4 final crispr M19 U2OS 144 1852 Elongated +0.07700219743069642 4.55721389353761e-06 BR00116999 PAK1 final crispr K10 U2OS 144 2176 Elongated +0.12560975609756098 4.6859241362220994e-06 BR00116998 SLC7A11 final crispr P05 U2OS 144 820 Elongated +0.19817073170731708 4.767909394484241e-06 BR00116998 CHRM3 final crispr B17 U2OS 144 328 Elongated +0.1099882741711971 4.8387585966799425e-06 BR00116996 LCK final crispr O13 U2OS 144 1060 Elongated +0.08717861399625404 5.105021483118522e-06 BR00116996 JAK1 final crispr M21 U2OS 144 1680 Elongated +0.08279569892473118 5.7370836025887185e-06 BR00116996 UGT1A9 final crispr J01 U2OS 144 1860 Elongated +0.07757805108798486 5.906672302740547e-06 BR00116998 CSK final crispr B11 U2OS 144 2114 Elongated +0.09913140148553558 5.974933502640054e-06 BR00116996 GPR119 final crispr P21 U2OS 144 1280 Elongated +0.07387202646504808 6.068068984302702e-06 BR00116996 HCK final crispr M23 U2OS 144 2316 Elongated 0.32890222984562606 5.025924448072699e-112 BR00116996 ABL1 final crispr P20 U2OS 144 2332 Grape 0.3504773669444328 1.063910955126847e-109 BR00116996 OPRM1 final crispr P22 U2OS 144 2002 Grape 0.3342696629213483 1.8392205171513684e-88 BR00116996 CHRM2 final crispr O22 U2OS 144 1780 Grape @@ -1109,6 +11009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.3185378590078329 4.2075324157825916e-69 BR00116996 S1PR1 final crispr P23 U2OS 144 1532 Grape 0.34447900466562986 4.742796945566292e-68 BR00116996 TGFBR1 final crispr P24 U2OS 144 1286 Grape 0.25471698113207547 7.522527839618944e-67 BR00116996 P2RY12 final crispr O21 U2OS 144 2332 Grape +0.3104138851802403 3.874707634156078e-64 BR00116996 P2RY12 final crispr P19 U2OS 144 1498 Grape +0.2738691090007773 8.502032517364278e-61 BR00116996 OPRM1 final crispr C23 U2OS 144 1828 Grape +0.24149654539586132 1.0974506112038114e-59 BR00116996 HCK final crispr M23 U2OS 144 2316 Grape +0.28491271820448877 9.572553978291334e-58 BR00116996 SLCO2B1 final crispr A21 U2OS 144 1604 Grape +0.2745316820327711 4.645299340242612e-55 BR00116996 GRIN2A final crispr A23 U2OS 144 1642 Grape +0.2407743304316658 2.056780889569022e-52 BR00116996 FPR1 final crispr N22 U2OS 144 2038 Grape +0.2568612481278844 5.5496707810029244e-52 BR00116996 HIF1A final crispr M24 U2OS 144 1772 Grape +0.1972407784173953 6.1332267418819e-51 BR00116996 IGF1R final crispr M22 U2OS 144 2964 Grape +0.374374262666199 5.805883681725819e-50 BR00116996 FFAR2 final crispr A24 U2OS 144 794 Grape +0.21805710533741798 4.960381591157337e-49 BR00116996 HPGDS final crispr P14 U2OS 144 2330 Grape +0.2918943021892103 1.6618137875147798e-48 BR00116996 GPR119 final crispr P21 U2OS 144 1280 Grape +0.2977050517503592 9.940574660115866e-45 BR00116996 KCNH7 final crispr P16 U2OS 144 1134 Grape +0.22533340192983697 1.432208750061868e-44 BR00116996 SLCO2B1 final crispr I24 U2OS 144 1982 Grape +0.1860770063398794 2.1414069182547752e-44 BR00116996 VEGFA final crispr C24 U2OS 144 2900 Grape +0.33103113365348297 2.6123772661602325e-42 BR00116996 ADA final crispr O24 U2OS 144 862 Grape +0.17837891860963012 6.87621124972388e-41 BR00116996 AKR1B1 final crispr L21 U2OS 144 2908 Grape +0.26862123613312205 1.90286383420941e-40 BR00116996 ICAM1 final crispr I12 U2OS 144 1262 Grape +0.23743718592964824 9.128312877521287e-40 BR00116996 HSD11B1 final crispr O23 U2OS 144 1592 Grape +0.24715099715099714 4.789040299772261e-38 BR00116996 CACNA2D3 final crispr N24 U2OS 144 1404 Grape +0.20571978982184116 5.172254915570349e-38 BR00116996 CACNG1 final crispr N23 U2OS 144 2022 Grape +0.19669595177277652 6.10902403554271e-38 BR00116996 FFAR4 final crispr G11 U2OS 144 2210 Grape +0.19902162868992 4.967791455257201e-37 BR00116996 PTGIR final crispr G10 U2OS 144 2110 Grape +0.1800511179168783 6.50163279291163e-37 BR00116996 ALK final crispr I15 U2OS 144 2572 Grape +0.16839557399723376 3.31977152526006e-36 BR00116996 ASIC1 final crispr M20 U2OS 144 2892 Grape +0.20072506013589977 3.6154392168892004e-36 BR00116999 HIF1A final crispr M24 U2OS 144 2020 Grape +0.3148741525030185 1.5705644194787068e-34 BR00116996 CCND1 final crispr B23 U2OS 144 776 Grape +0.20320855614973263 3.464083112828013e-34 BR00116999 S1PR1 final crispr P23 U2OS 144 1870 Grape +0.1523226147174555 1.0604830654111225e-33 BR00116996 CYP1A2 final crispr K22 U2OS 144 3280 Grape +0.17067108533554268 4.162706382179254e-31 BR00116996 CCR1 final crispr O17 U2OS 144 2414 Grape +0.2556368857296374 5.12953486269839e-31 BR00116996 CHRM3 final crispr B21 U2OS 144 1066 Grape +0.1459132368331972 2.7634735036034513e-30 BR00116998 ALDH2 final crispr A10 U2OS 144 3212 Grape +0.18653648509763618 5.351643591137335e-30 BR00116996 ELANE final crispr N19 U2OS 144 1946 Grape +0.22465960665658094 1.217952751069135e-29 BR00116996 BTK final crispr P17 U2OS 144 1322 Grape +0.17000839905336138 1.4379636940686e-29 BR00116996 GPR55 final crispr C21 U2OS 144 2308 Grape +0.21188623691189412 1.179074294482601e-28 BR00116996 S1PR2 final crispr J23 U2OS 144 1434 Grape +0.17875349355740272 5.581878984481937e-28 BR00116996 DYRK1B final crispr K14 U2OS 144 1970 Grape +0.1674390399591472 7.700389810719678e-28 BR00116996 PDPK1 final crispr N18 U2OS 144 2238 Grape +0.1932176358865063 1.4577309035851424e-27 BR00116999 ADH1C final crispr P04 U2OS 144 1660 Grape +0.1335243553008596 1.589415935978925e-27 BR00116999 PDE3A final crispr P18 U2OS 144 3490 Grape +0.15272905678891205 2.9717866659636125e-27 BR00116997 CACNA2D3 final crispr N24 U2OS 144 2630 Grape +0.2004501645808477 4.575809800039696e-26 BR00116996 PORCN final crispr L13 U2OS 144 1458 Grape +0.24193548387096775 6.999584190171971e-26 BR00116996 FOXM1 final crispr A19 U2OS 144 992 Grape +0.17160367722165476 1.387504290857174e-25 BR00116996 KCNQ2 final crispr P13 U2OS 144 1958 Grape +0.20564437066182142 1.5218968879724707e-25 BR00116996 ITGB2 final crispr A17 U2OS 144 1356 Grape +0.16705420219482922 4.2368157183289905e-25 BR00116996 KCNK1 final crispr N20 U2OS 144 2022 Grape +0.15519172184745578 5.7786125797450015e-25 BR00116996 PDE7A final crispr C22 U2OS 144 2328 Grape +0.2138157894736842 9.559477895857882e-25 BR00116996 S1PR1 final crispr A18 U2OS 144 1216 Grape +0.17341384071986815 1.3559952453136708e-24 BR00116996 PLD1 final crispr F11 U2OS 144 1832 Grape +0.19019257154498956 5.050520209602347e-24 BR00116996 SCNN1G final crispr P15 U2OS 144 1492 Grape +0.17930743243243244 8.109765635129102e-24 BR00116999 CDK2 final crispr F08 U2OS 144 1664 Grape +0.14013192237818392 1.3904284364682214e-23 BR00116997 UGT1A9 final crispr B18 U2OS 144 2694 Grape +0.12574493444576879 1.5769266898298949e-23 BR00116996 PNLIP final crispr C18 U2OS 144 3356 Grape +0.14496805111821087 2.3488671430584807e-23 BR00116997 HSD11B1 final crispr O23 U2OS 144 2504 Grape +0.17547420870845365 4.506203733997712e-23 BR00116996 GABRB2 final crispr L22 U2OS 144 1682 Grape +0.15681307885012982 6.653277847397474e-23 BR00116996 PDE4D final crispr J24 U2OS 144 2094 Grape +0.3103448275862069 1.3296511097977976e-22 BR00116996 PLA2G1B final crispr J11 U2OS 144 522 Grape +0.2293131121811545 2.3098143970011015e-22 BR00116999 TUBB final crispr J17 U2OS 144 948 Grape +0.10118349569438441 1.1876374562823968e-21 BR00116998 TNF final crispr I10 U2OS 144 4750 Grape +0.16535433070866143 1.249977368696239e-21 BR00116996 F10 final crispr H07 U2OS 144 1778 Grape +0.18804327447735655 1.9393364945640356e-21 BR00116999 PAK4 final crispr M16 U2OS 144 1358 Grape +0.17715357849137114 2.7373525983124814e-21 BR00116996 PTGIS final crispr I16 U2OS 144 1518 Grape +0.19400630914826497 2.8209482454098267e-21 BR00116997 S1PR1 final crispr P23 U2OS 144 1268 Grape +0.12003610108303249 2.842267112100217e-21 BR00116997 HDAC6 final crispr L10 U2OS 144 3324 Grape +0.18532181351834642 3.868962519837426e-21 BR00116996 SLC29A1 final crispr N21 U2OS 144 1378 Grape +0.1927713693142349 4.981048671709936e-21 BR00116996 KDR final crispr O18 U2OS 144 1268 Grape +0.2192622950819672 5.85055368713133e-21 BR00116996 HRH4 final crispr H24 U2OS 144 976 Grape +0.1464879852125693 1.1635565624343887e-20 BR00116996 SCNN1G final crispr G24 U2OS 144 2164 Grape +0.17756165425630352 1.2660382784018434e-20 BR00116996 PIK3CG final crispr I08 U2OS 144 1466 Grape +0.26215137292981605 1.3418390180265292e-20 BR00116996 MAPK14 final crispr A20 U2OS 144 666 Grape +0.13102464888854198 1.63879586557942e-20 BR00116996 HDAC6 final crispr K12 U2OS 144 2680 Grape +0.15729699666295885 6.907884587413972e-20 BR00116996 FOXM1 final crispr F23 U2OS 144 1800 Grape +0.170775987274362 8.124100209080086e-20 BR00116996 TNNC1 final crispr D09 U2OS 144 1520 Grape +0.12815050211744428 1.5051198286792627e-19 BR00116997 HRH4 final crispr A08 U2OS 144 2664 Grape +0.15005192107995846 2.5204270005829044e-19 BR00116996 ATP5F1D final crispr G21 U2OS 144 1926 Grape +0.17211396850572108 2.5598976935280226e-19 BR00116999 CLK1 final crispr N05 U2OS 144 1456 Grape +0.1810054653986382 3.1472727415702094e-19 BR00116996 TBXAS1 final crispr E24 U2OS 144 1308 Grape +0.18862561973942119 7.882414016189687e-19 BR00116999 PTGIR final crispr G10 U2OS 144 1180 Grape +0.13805631244323344 1.0469011756156906e-18 BR00116999 TGFBR1 final crispr P24 U2OS 144 2202 Grape +0.13533066785132533 1.8023531287696782e-18 BR00116999 DNMT3A final crispr L04 U2OS 144 2250 Grape +0.1630081737598703 2.2973257750511673e-18 BR00116996 DCK final crispr J08 U2OS 144 1538 Grape +0.16101808989132932 3.645357051806277e-18 BR00116996 RET final crispr I03 U2OS 144 1562 Grape +0.15861935188525894 3.740385410102134e-18 BR00116996 TUBB final crispr K13 U2OS 144 1606 Grape +0.17455547207613323 3.771711769057944e-18 BR00116996 RNASE1 final crispr I13 U2OS 144 1332 Grape +0.1741405082212257 3.946124818241117e-18 BR00116996 SIRT2 final crispr O19 U2OS 144 1338 Grape +0.14941303256808555 4.086282126136916e-18 BR00116996 USP1 final crispr K18 U2OS 144 1816 Grape +0.2030612244897959 4.3455541634249475e-18 BR00116996 ADORA2A final crispr B22 U2OS 144 980 Grape +0.1889679715302491 4.959325436125038e-18 BR00116996 ITGB2 final crispr D23 U2OS 144 1124 Grape +0.14333459655162817 8.30979829551444e-18 BR00116997 ADA final crispr O06 U2OS 144 1934 Grape +0.1092814371257485 8.830277260728688e-18 BR00116999 ANXA1 final crispr G01 U2OS 144 3340 Grape +0.14635473340587596 1.4003603419355516e-17 BR00116999 AGER final crispr K20 U2OS 144 1838 Grape 0.30641863126893065 1.7815267362102073e-83 BR00116996 OPRM1 final crispr P22 U2OS 144 2002 Hole 0.25900514579759865 3.9327777252798007e-69 BR00116996 ABL1 final crispr P20 U2OS 144 2332 Hole 0.2668908698870402 5.021054791338029e-61 BR00116999 CACNA2D3 final crispr N24 U2OS 144 1932 Hole @@ -1119,6 +11109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.3218690983650785 4.45157834242038e-40 BR00116996 ADA final crispr O24 U2OS 144 862 Hole 0.21118486093653854 5.04031351733933e-40 BR00116996 BTK final crispr D24 U2OS 144 2028 Hole 0.24232309746328437 5.361141652184122e-39 BR00116996 P2RY12 final crispr P19 U2OS 144 1498 Hole +0.3173325255874757 7.865536635535747e-36 BR00116996 FFAR2 final crispr A24 U2OS 144 794 Hole +0.20498263945030715 3.659480022860672e-34 BR00116996 OPRM1 final crispr C23 U2OS 144 1828 Hole +0.2032825469333185 5.488561913990529e-34 BR00116996 HTR3A final crispr O20 U2OS 144 1856 Hole +0.21282202879996207 4.802535210895987e-33 BR00116996 GRIN2A final crispr A23 U2OS 144 1642 Hole +0.21508728179551123 6.780227804423854e-33 BR00116996 SLCO2B1 final crispr A21 U2OS 144 1604 Hole +0.21367521367521367 1.8029134145863785e-28 BR00116996 CACNA2D3 final crispr N24 U2OS 144 1404 Hole +0.16462461508874482 7.87484730596476e-28 BR00116996 HCK final crispr M23 U2OS 144 2316 Hole +0.2185056684910086 2.4918730867586637e-27 BR00116996 GPR119 final crispr P21 U2OS 144 1280 Hole +0.2299026635596215 7.570177087818968e-27 BR00116996 KCNH7 final crispr P16 U2OS 144 1134 Hole +0.18418187753982096 8.321557663738656e-27 BR00116996 HIF1A final crispr M24 U2OS 144 1772 Hole +0.16037735849056603 1.3943715452487936e-26 BR00116996 P2RY12 final crispr O21 U2OS 144 2332 Hole +0.16179626854130866 8.340947724379166e-24 BR00116996 FPR1 final crispr N22 U2OS 144 2038 Hole +0.1542570667557742 4.302819380961826e-21 BR00116996 SLCO2B1 final crispr I24 U2OS 144 1982 Hole +0.14215396419343 5.492866354661525e-21 BR00116996 HPGDS final crispr P14 U2OS 144 2330 Hole +0.18532526475037822 2.986445893932532e-20 BR00116996 BTK final crispr P17 U2OS 144 1322 Hole +0.1658291457286432 1.6070824696853399e-19 BR00116996 HSD11B1 final crispr O23 U2OS 144 1592 Hole +0.11990745917141464 1.1716285384575526e-18 BR00116996 VEGFA final crispr C24 U2OS 144 2900 Hole +0.1796277253951932 2.0903109249135844e-18 BR00116996 KDR final crispr O18 U2OS 144 1268 Hole +0.11764825105678083 2.300134245714451e-18 BR00116996 IGF1R final crispr M22 U2OS 144 2964 Hole +0.13869862344252745 1.992109128441018e-17 BR00116996 CACNG1 final crispr N23 U2OS 144 2022 Hole +0.1892520853702578 3.115867963449117e-17 BR00116996 CHRM3 final crispr B21 U2OS 144 1066 Hole +0.15821998817267888 5.442404036723848e-16 BR00116999 KCNN1 final crispr D01 U2OS 144 1424 Hole +0.13689839572192514 1.088821562668325e-15 BR00116999 S1PR1 final crispr P23 U2OS 144 1870 Hole +0.22301343259427092 5.39716396904988e-15 BR00116996 MAPK14 final crispr A20 U2OS 144 666 Hole +0.16167192429022081 7.074575991260532e-15 BR00116997 S1PR1 final crispr P23 U2OS 144 1268 Hole +0.12686004869660641 1.3324249665075615e-14 BR00116999 HIF1A final crispr M24 U2OS 144 2020 Hole +0.16282894736842105 1.7482946128195894e-14 BR00116996 S1PR1 final crispr A18 U2OS 144 1216 Hole +0.0986979224778524 2.1669390539537513e-14 BR00116996 CYP1A2 final crispr K22 U2OS 144 3280 Hole +0.12744090441932168 3.4766458570732737e-14 BR00116996 ELANE final crispr N19 U2OS 144 1946 Hole +0.26673734595763443 4.2202002338603775e-14 BR00116996 KCNN4 final crispr A22 U2OS 144 436 Hole +0.17641129032258066 6.759914917069529e-14 BR00116996 FOXM1 final crispr A19 U2OS 144 992 Hole +0.14456052326108376 1.605050666997092e-13 BR00116996 S1PR2 final crispr J23 U2OS 144 1434 Hole +0.19627433029494884 1.6145498884136554e-13 BR00116996 CCND1 final crispr B23 U2OS 144 776 Hole +0.1178373382624769 1.6741287724861806e-13 BR00116996 SCNN1G final crispr G24 U2OS 144 2164 Hole +0.10674397580410212 3.057747615356828e-13 BR00116999 CYP3A4 final crispr D04 U2OS 144 2580 Hole +0.09928912736215474 6.305786612148941e-13 BR00116996 AKR1B1 final crispr L21 U2OS 144 2908 Hole +0.11648985663628936 2.0888583435882996e-12 BR00116996 KCNK1 final crispr N20 U2OS 144 2022 Hole +0.16393442622950818 7.311956859213054e-12 BR00116996 HRH4 final crispr H24 U2OS 144 976 Hole +0.14291833803793394 8.87587818344293e-12 BR00116996 SIRT2 final crispr P01 U2OS 144 1272 Hole +0.13602654431532485 2.0075795491756793e-11 BR00116996 ITGB2 final crispr A17 U2OS 144 1356 Hole +0.1486019302111256 2.2859691216791917e-11 BR00116997 TNNC1 final crispr D09 U2OS 144 1134 Hole +0.10626702997275204 3.045793765683148e-11 BR00116999 TGFBR1 final crispr P24 U2OS 144 2202 Hole +0.08592814371257484 3.794196407838709e-11 BR00116999 ANXA1 final crispr G01 U2OS 144 3340 Hole +0.09621565938040755 4.82762604609579e-11 BR00116997 CA5A final crispr M01 U2OS 144 2628 Hole +0.0912863070539419 6.636591947910422e-11 BR00116996 ASIC1 final crispr M20 U2OS 144 2892 Hole +0.14143640951500075 1.4735209281324604e-10 BR00116998 BRD4 final crispr M19 U2OS 144 1158 Hole +0.10164488382484362 1.594720214708619e-10 BR00116996 PDPK1 final crispr N18 U2OS 144 2238 Hole +0.13153961136023917 1.6644965563748638e-10 BR00116996 SIRT2 final crispr O19 U2OS 144 1338 Hole +0.09139078973789717 3.80428387880888e-10 BR00116997 HRH4 final crispr A08 U2OS 144 2664 Hole +0.15299149873774542 3.985822915445606e-10 BR00116999 CDK7 final crispr I14 U2OS 144 946 Hole +0.10572012257405516 6.047245200486922e-10 BR00116996 KCNQ2 final crispr P13 U2OS 144 1958 Hole +0.1234143081058852 6.253572749183846e-10 BR00116999 AURKB final crispr C13 U2OS 144 1426 Hole +0.08074381294584212 1.4663108229827558e-09 BR00116998 ALDH2 final crispr A10 U2OS 144 3212 Hole +0.11034142733883891 1.6135227830198333e-09 BR00116999 RGS4 final crispr N11 U2OS 144 1708 Hole +0.1298685917319948 3.2974379564157443e-09 BR00116996 ANXA1 final crispr F24 U2OS 144 1190 Hole +0.09756070874164849 4.136632669086943e-09 BR00116996 PDE4D final crispr J24 U2OS 144 2094 Hole +0.08989229494614748 6.6027414652120474e-09 BR00116996 CCR1 final crispr O17 U2OS 144 2414 Hole +0.1633231599282146 6.629541874239462e-09 BR00116998 FFAR2 final crispr A24 U2OS 144 726 Hole +0.18498085734011172 6.871405240099029e-09 BR00116996 KCNN1 final crispr B24 U2OS 144 564 Hole +0.14226002618955663 1.001644299676447e-08 BR00116999 CDK4 final crispr B15 U2OS 144 934 Hole +0.11319444444444444 1.8775638754022843e-08 BR00116998 FOXM1 final crispr A19 U2OS 144 1440 Hole +0.11766352458729593 2.3258655940462762e-08 BR00116996 TBXAS1 final crispr E24 U2OS 144 1308 Hole +0.08212574359567679 2.430551260088051e-08 BR00116997 UGT1A9 final crispr B18 U2OS 144 2694 Hole +0.09916133832897288 2.5111719579510693e-08 BR00116996 CA14 final crispr C19 U2OS 144 1832 Hole +0.14864864864864866 2.9202724841380327e-08 BR00116999 BTK final crispr P17 U2OS 144 814 Hole +0.09570912578870854 3.635686005720459e-08 BR00116997 ADA final crispr O06 U2OS 144 1934 Hole +0.08652672759453127 4.775348122495625e-08 BR00116996 PDE7A final crispr C22 U2OS 144 2328 Hole +0.09052532833020638 5.0663068501118684e-08 BR00116999 ANXA1 final crispr F24 U2OS 144 2132 Hole +0.11188682864983443 5.20320980938702e-08 BR00116997 DYRK1B final crispr N16 U2OS 144 1384 Hole +0.08112351281736783 5.4406262076511244e-08 BR00116997 CACNA2D3 final crispr N24 U2OS 144 2630 Hole +0.1326530612244898 6.21439483710926e-08 BR00116996 ADORA2A final crispr B22 U2OS 144 980 Hole +0.0974823878383389 6.521540640301494e-08 BR00116996 FOXM1 final crispr F23 U2OS 144 1800 Hole +0.11050686694782087 9.125351509154794e-08 BR00116996 SLC29A1 final crispr N21 U2OS 144 1378 Hole +0.12266943778485104 9.489400907374168e-08 BR00116998 PPAT final crispr E13 U2OS 144 1106 Hole +0.12764647176700752 1.2568045395746847e-07 BR00116996 ALDH2 final crispr A10 U2OS 144 1006 Hole +0.07370712905311515 1.616179458900924e-07 BR00116997 ADH1C final crispr D02 U2OS 144 2992 Hole +0.1413170758907827 1.7182535081437826e-07 BR00116996 HPGDS final crispr B19 U2OS 144 804 Hole +0.07948071269345823 1.76015387626927e-07 BR00116997 SLCO2B1 final crispr I24 U2OS 144 2556 Hole +0.1379569049230081 1.878361622119751e-07 BR00116998 MAPK8 final crispr D13 U2OS 144 842 Hole +0.0862708719851577 2.1141042073484428e-07 BR00116997 DYRK1B final crispr K14 U2OS 144 2156 Hole +0.08164983164983165 2.603540571943811e-07 BR00116996 CATSPER4 final crispr P02 U2OS 144 2376 Hole +0.08200673575557328 3.4548948966745927e-07 BR00116996 GPR55 final crispr C21 U2OS 144 2308 Hole +0.09480493743276146 4.793195489365883e-07 BR00116996 GABRB2 final crispr L22 U2OS 144 1682 Hole +0.13318039729756984 5.282723831919223e-07 BR00116998 AURKB final crispr C13 U2OS 144 846 Hole +0.12124807649501099 5.687782085808379e-07 BR00116998 GJB4 final crispr H01 U2OS 144 1018 Hole +0.11433768287860814 6.8536934503126e-07 BR00116996 ITGB2 final crispr D23 U2OS 144 1124 Hole +0.09124341770001698 1.4742647955418795e-06 BR00116996 PIK3CG final crispr E22 U2OS 144 1682 Hole +0.10667752442996743 1.6702880206036087e-06 BR00116998 SLCO2B1 final crispr A21 U2OS 144 1228 Hole +0.08515057113187954 1.7000835148630632e-06 BR00116996 ATP5F1D final crispr G21 U2OS 144 1926 Hole +0.05400636145005597 1.8163664116438496e-06 BR00116998 TNF final crispr I10 U2OS 144 4750 Hole 0.330188679245283 6.447936782641457e-113 BR00116996 ABL1 final crispr P20 U2OS 144 2332 Interphase 0.35439361038163436 4.150174560872394e-112 BR00116996 OPRM1 final crispr P22 U2OS 144 2002 Interphase 0.3283364979242429 1.1368585976939567e-92 BR00116999 CACNA2D3 final crispr N24 U2OS 144 1932 Interphase @@ -1129,6 +11209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.28648799493136623 1.0522509010325289e-66 BR00116996 OPRM1 final crispr C23 U2OS 144 1828 Interphase 0.30240320427236317 7.705252883229948e-61 BR00116996 P2RY12 final crispr P19 U2OS 144 1498 Interphase 0.24099485420240138 8.138450203920923e-60 BR00116996 P2RY12 final crispr O21 U2OS 144 2332 Interphase +0.26958688466752084 8.288889622650361e-60 BR00116996 HTR3A final crispr O20 U2OS 144 1856 Interphase +0.25509549403472137 2.1067815152497732e-58 BR00116996 BTK final crispr D24 U2OS 144 2028 Interphase +0.23284754942629496 1.742778211941792e-55 BR00116996 HCK final crispr M23 U2OS 144 2316 Interphase +0.2609837270434548 1.2603604624858672e-49 BR00116996 GRIN2A final crispr A23 U2OS 144 1642 Interphase +0.3654210375282977 1.343315858820298e-47 BR00116996 FFAR2 final crispr A24 U2OS 144 794 Interphase +0.22755615808234608 8.247908830186071e-47 BR00116996 FPR1 final crispr N22 U2OS 144 2038 Interphase +0.25374064837905236 9.347719736320048e-46 BR00116996 SLCO2B1 final crispr A21 U2OS 144 1604 Interphase +0.18446786115578415 1.3384780848746848e-44 BR00116996 IGF1R final crispr M22 U2OS 144 2964 Interphase +0.2338750347746665 4.651087386898718e-43 BR00116996 HIF1A final crispr M24 U2OS 144 1772 Interphase +0.3322802568391518 1.0196843278155146e-42 BR00116996 ADA final crispr O24 U2OS 144 862 Interphase +0.26999242572322124 1.8796213381823813e-41 BR00116996 GPR119 final crispr P21 U2OS 144 1280 Interphase +0.2854496576179424 2.6431974276884853e-41 BR00116996 KCNH7 final crispr P16 U2OS 144 1134 Interphase +0.254985754985755 1.6979246267928943e-40 BR00116996 CACNA2D3 final crispr N24 U2OS 144 1404 Interphase +0.18767629857374984 2.4918031359160904e-36 BR00116996 HPGDS final crispr P14 U2OS 144 2330 Interphase +0.22613065326633167 4.4683949575608696e-36 BR00116996 HSD11B1 final crispr O23 U2OS 144 1592 Interphase +0.19725802731221387 6.071976846977293e-35 BR00116996 CACNG1 final crispr N23 U2OS 144 2022 Interphase +0.19179604254339339 5.224935490275827e-33 BR00116999 HIF1A final crispr M24 U2OS 144 2020 Interphase +0.2344931921331316 2.8009456601891884e-32 BR00116996 BTK final crispr P17 U2OS 144 1322 Interphase +0.2329635499207607 1.9619291893653185e-30 BR00116996 ICAM1 final crispr I12 U2OS 144 1262 Interphase +0.19144385026737967 2.2877118392308574e-30 BR00116999 S1PR1 final crispr P23 U2OS 144 1870 Interphase +0.1855299411003932 2.3588943478281496e-30 BR00116996 SLCO2B1 final crispr I24 U2OS 144 1982 Interphase +0.15128684620369 1.81983350613895e-29 BR00116996 AKR1B1 final crispr L21 U2OS 144 2908 Interphase +0.18396711202466598 3.485055474740161e-29 BR00116996 ELANE final crispr N19 U2OS 144 1946 Interphase +0.24718970483312633 5.228690412097086e-29 BR00116996 CHRM3 final crispr B21 U2OS 144 1066 Interphase +0.14880041869372315 2.0008556003858452e-28 BR00116996 VEGFA final crispr C24 U2OS 144 2900 Interphase +0.17210535883932865 1.0799256273400618e-26 BR00116996 KCNK1 final crispr N20 U2OS 144 2022 Interphase +0.1330177824430207 3.246321944794646e-25 BR00116998 ALDH2 final crispr A10 U2OS 144 3212 Interphase +0.14390663418060984 1.2089766036329618e-24 BR00116996 HDAC6 final crispr K12 U2OS 144 2680 Interphase +0.23668032786885246 2.200338619469831e-24 BR00116996 HRH4 final crispr H24 U2OS 144 976 Interphase +0.192284413568064 1.258907582071335e-23 BR00116996 S1PR2 final crispr J23 U2OS 144 1434 Interphase +0.1242838759586132 1.421170091092266e-22 BR00116996 CYP1A2 final crispr K22 U2OS 144 3280 Interphase +0.15139546364215498 1.4399686874995285e-22 BR00116996 FFAR4 final crispr G11 U2OS 144 2210 Interphase +0.13817216326000534 2.177477696334772e-22 BR00116997 CACNA2D3 final crispr N24 U2OS 144 2630 Interphase +0.2506003794663588 5.195481976637715e-22 BR00116996 CCND1 final crispr B23 U2OS 144 776 Interphase +0.2217741935483871 8.818696446645434e-22 BR00116996 FOXM1 final crispr A19 U2OS 144 992 Interphase +0.15130572869821887 1.4901198484027607e-21 BR00116996 PTGIR final crispr G10 U2OS 144 2110 Interphase +0.1371493588769556 1.4970479688814157e-21 BR00116996 ALK final crispr I15 U2OS 144 2572 Interphase +0.145198199923401 4.380249382055785e-21 BR00116996 PDPK1 final crispr N18 U2OS 144 2238 Interphase +0.11823104693140794 1.1950925566225387e-20 BR00116997 HDAC6 final crispr L10 U2OS 144 3324 Interphase +0.12586445366528354 2.2624161013471105e-20 BR00116996 ASIC1 final crispr M20 U2OS 144 2892 Interphase +0.13074569686139934 2.4503725837778402e-20 BR00116997 HRH4 final crispr A08 U2OS 144 2664 Interphase +0.3174689815883946 4.42040783824722e-20 BR00116996 KCNN4 final crispr A22 U2OS 144 436 Interphase +0.13628831814415907 5.903314705701651e-20 BR00116996 CCR1 final crispr O17 U2OS 144 2414 Interphase +0.1725995265491273 7.456457516280773e-20 BR00116996 SCNN1G final crispr P15 U2OS 144 1492 Interphase +0.14579763068934312 7.65338115742175e-20 BR00116996 PDE4D final crispr J24 U2OS 144 2094 Interphase +0.21122448979591837 1.5076261961968397e-19 BR00116996 ADORA2A final crispr B22 U2OS 144 980 Interphase +0.13218849840255592 1.7653675976911936e-19 BR00116997 HSD11B1 final crispr O23 U2OS 144 2504 Interphase +0.17368322491622315 3.3987622588168567e-19 BR00116999 KCNN1 final crispr D01 U2OS 144 1424 Interphase +0.25192407976839115 4.0908781079757036e-19 BR00116996 MAPK14 final crispr A20 U2OS 144 666 Interphase +0.15248784280429956 5.121047020877233e-19 BR00116996 CA14 final crispr C19 U2OS 144 1832 Interphase +0.1850916261973116 9.197461126429539e-19 BR00116997 GRIN2A final crispr A23 U2OS 144 1222 Interphase +0.12487779481097967 9.29263333998328e-19 BR00116997 UGT1A9 final crispr B18 U2OS 144 2694 Interphase +0.11197604790419162 1.19600360960281e-18 BR00116999 ANXA1 final crispr G01 U2OS 144 3340 Interphase +0.14506360016412945 1.5185557055881327e-18 BR00116996 DYRK1B final crispr K14 U2OS 144 1970 Interphase +0.15728908413437143 1.925996853514656e-18 BR00116999 ADH1C final crispr P04 U2OS 144 1660 Interphase +0.23771475600973904 1.986325449444099e-18 BR00116998 FFAR2 final crispr A24 U2OS 144 726 Interphase +0.10773638968481375 4.748847016619037e-18 BR00116999 PDE3A final crispr P18 U2OS 144 3490 Interphase +0.13533151680290645 5.452726667979446e-18 BR00116999 TGFBR1 final crispr P24 U2OS 144 2202 Interphase +0.18174342105263158 5.853757241772368e-18 BR00116996 S1PR1 final crispr A18 U2OS 144 1216 Interphase +0.1305930568236549 9.795570058353389e-18 BR00116996 PDE7A final crispr C22 U2OS 144 2328 Interphase +0.17189835575485798 1.1257114693058413e-17 BR00116996 SIRT2 final crispr O19 U2OS 144 1338 Interphase +0.17248324988360195 5.2254498347162345e-17 BR00116996 KDR final crispr O18 U2OS 144 1268 Interphase +0.1321626617375231 6.93491023804085e-17 BR00116996 SCNN1G final crispr G24 U2OS 144 2164 Interphase +0.1742671009771987 1.0678787438382653e-16 BR00116998 SLCO2B1 final crispr A21 U2OS 144 1228 Interphase +0.17582764649483953 1.389791585491553e-16 BR00116996 ANXA1 final crispr F24 U2OS 144 1190 Interphase +0.16356797115345148 1.4761553054821163e-16 BR00116996 SLC29A1 final crispr N21 U2OS 144 1378 Interphase +0.1109134490013896 1.747937474133208e-16 BR00116997 ADH1C final crispr D02 U2OS 144 2992 Interphase +0.16732797290393914 1.786165427960213e-16 BR00116996 TBXAS1 final crispr E24 U2OS 144 1308 Interphase +0.13636363636363635 2.7762895888580647e-16 BR00116996 KCNQ2 final crispr P13 U2OS 144 1958 Interphase +0.12406730351356646 6.560593538198507e-16 BR00116996 GPR55 final crispr C21 U2OS 144 2308 Interphase +0.15499794943044384 8.260786407894432e-16 BR00116996 PIK3CG final crispr I08 U2OS 144 1466 Interphase +0.10907189087113027 1.1015581770087825e-15 BR00116996 CTSG final crispr G18 U2OS 144 2938 Interphase +0.11325757575757575 3.675141017439462e-15 BR00116997 OPRM1 final crispr C23 U2OS 144 2640 Interphase +0.1512968557113456 4.371121859634522e-15 BR00116996 PORCN final crispr L13 U2OS 144 1458 Interphase +0.11214100193097447 5.299627343239795e-15 BR00116996 CLK1 final crispr M11 U2OS 144 2656 Interphase +0.1719288841817031 7.104160705785978e-15 BR00116996 PRKCE final crispr I17 U2OS 144 1114 Interphase +0.13417334646636409 7.128386469920302e-15 BR00116996 PLD1 final crispr F11 U2OS 144 1832 Interphase +0.1608832807570978 9.794032363840943e-15 BR00116997 S1PR1 final crispr P23 U2OS 144 1268 Interphase +0.15508294009228638 9.963391107765212e-15 BR00116996 ITGB2 final crispr A17 U2OS 144 1356 Interphase +0.13596914304164115 2.177234550625231e-14 BR00116998 PDE4D final crispr P06 U2OS 144 1732 Interphase +0.11056257865318712 3.610184624321659e-14 BR00116999 CYP3A4 final crispr D04 U2OS 144 2580 Interphase +0.12229243634348066 4.2846223426064185e-14 BR00116999 CACNB4 final crispr B01 U2OS 144 2090 Interphase +0.14762233321588375 4.593087912017167e-14 BR00116999 PDE4D final crispr P06 U2OS 144 1426 Interphase +0.1564774922002674 4.9902880367130684e-14 BR00116996 SIRT2 final crispr P01 U2OS 144 1272 Interphase +0.11873840445269017 1.1793783083884518e-13 BR00116997 DYRK1B final crispr K14 U2OS 144 2156 Interphase +0.12739773085993353 1.3272798260220834e-13 BR00116996 CYP2A6 final crispr C07 U2OS 144 1856 Interphase +0.16323448003163304 1.3516369133100667e-13 BR00116996 ITGB2 final crispr D23 U2OS 144 1124 Interphase +0.10642626062700025 2.1059879911987932e-13 BR00116997 CA5A final crispr M01 U2OS 144 2628 Interphase +0.18211104362789757 2.4355093764962406e-13 BR00116997 KCNN1 final crispr B24 U2OS 144 890 Interphase +0.13200059453032104 3.262676243803376e-13 BR00116996 GABRB2 final crispr L22 U2OS 144 1682 Interphase 0.4485619884358339 1.2459171605335178e-175 BR00116999 CACNA2D3 final crispr N24 U2OS 144 1932 Large 0.41829378206623713 1.9743579605255536e-157 BR00116996 OPRM1 final crispr P22 U2OS 144 2002 Large 0.5124416796267496 3.158984124419357e-154 BR00116996 TGFBR1 final crispr P24 U2OS 144 1286 Large @@ -1139,6 +11309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.35808812141861546 1.129632112839946e-100 BR00116996 PDE3A final crispr P18 U2OS 144 1760 Large 0.3756281407035176 2.2186388856984942e-100 BR00116996 HSD11B1 final crispr O23 U2OS 144 1592 Large 0.34394728237631733 1.590543108800672e-96 BR00116996 OPRM1 final crispr C23 U2OS 144 1828 Large +0.37532637075718017 1.8747729007334383e-96 BR00116996 S1PR1 final crispr P23 U2OS 144 1532 Large +0.3497506234413965 1.941189036683083e-87 BR00116996 SLCO2B1 final crispr A21 U2OS 144 1604 Large +0.36114819759679573 3.390900158339213e-87 BR00116996 P2RY12 final crispr P19 U2OS 144 1498 Large +0.32032085561497325 3.225347456867615e-85 BR00116999 S1PR1 final crispr P23 U2OS 144 1870 Large +0.29518619436875565 5.468876817482973e-85 BR00116999 TGFBR1 final crispr P24 U2OS 144 2202 Large +0.4738991805630839 4.2013123473862682e-81 BR00116996 FFAR2 final crispr A24 U2OS 144 794 Large +0.299444543274395 1.2079601936839346e-80 BR00116996 BTK final crispr D24 U2OS 144 2028 Large +0.24484704062656706 1.4868269566293446e-78 BR00116996 IGF1R final crispr M22 U2OS 144 2964 Large +0.24643456126369379 7.21452103926229e-78 BR00116996 VEGFA final crispr C24 U2OS 144 2900 Large +0.2927721355126432 1.431735494872208e-77 BR00116996 FPR1 final crispr N22 U2OS 144 2038 Large +0.27386002535885917 7.372544248261672e-77 BR00116996 HCK final crispr M23 U2OS 144 2316 Large +0.2892725393271638 6.198996563911364e-75 BR00116999 HIF1A final crispr M24 U2OS 144 2020 Large +0.28763590621737956 3.6509458440773175e-74 BR00116996 KCNK1 final crispr N20 U2OS 144 2022 Large +0.2541373796319009 1.300992753523064e-66 BR00116996 HPGDS final crispr P14 U2OS 144 2330 Large +0.41257216856418283 2.863385183895152e-66 BR00116996 ADA final crispr O24 U2OS 144 862 Large +0.35420470695551604 1.294560761195863e-63 BR00116996 KCNH7 final crispr P16 U2OS 144 1134 Large +0.3176638176638177 5.189268479724663e-63 BR00116996 CACNA2D3 final crispr N24 U2OS 144 1404 Large +0.373469387755102 3.211554168635911e-61 BR00116996 ADORA2A final crispr B22 U2OS 144 980 Large +0.25495390624083697 3.31066851435528e-58 BR00116996 CACNG1 final crispr N23 U2OS 144 2022 Large +0.26526551445601915 7.37236896459957e-58 BR00116996 HTR3A final crispr O20 U2OS 144 1856 Large +0.26057816773393666 2.0183392421256538e-53 BR00116996 HIF1A final crispr M24 U2OS 144 1772 Large +0.22220498592040375 6.978510291012063e-51 BR00116996 PDE7A final crispr C22 U2OS 144 2328 Large +0.29512680805316654 9.09823257220477e-50 BR00116996 GPR119 final crispr P21 U2OS 144 1280 Large +0.2267630319886852 7.256022157456495e-48 BR00116997 TGFBR1 final crispr P24 U2OS 144 2106 Large +0.3420260147788238 1.044259439537607e-46 BR00116997 KCNN1 final crispr B24 U2OS 144 890 Large +0.27754974880502653 1.5622805563503386e-46 BR00116996 ITGB2 final crispr A17 U2OS 144 1356 Large +0.19859164075295271 6.3740656146989e-46 BR00116997 CACNA2D3 final crispr N24 U2OS 144 2630 Large +0.1886569205876446 1.003436475956836e-45 BR00116996 AKR1B1 final crispr L21 U2OS 144 2908 Large +0.28536184210526316 5.150563960430445e-44 BR00116996 S1PR1 final crispr A18 U2OS 144 1216 Large +0.2107545799821269 5.834702558093584e-44 BR00116996 PDPK1 final crispr N18 U2OS 144 2238 Large +0.20250050101591768 7.494005694480391e-42 BR00116996 GPR55 final crispr C21 U2OS 144 2308 Large +0.2758874191730836 2.456075432223969e-41 BR00116997 GRIN2A final crispr A23 U2OS 144 1222 Large +0.2585696077698759 6.458498671214125e-41 BR00116996 SLC29A1 final crispr N21 U2OS 144 1378 Large +0.17600276625172892 1.5776673024455317e-39 BR00116996 ASIC1 final crispr M20 U2OS 144 2892 Large +0.28775555144500525 1.683045086934081e-39 BR00116996 CHRM3 final crispr B21 U2OS 144 1066 Large +0.36258563953174733 2.0575536848675613e-39 BR00116996 MAPK14 final crispr A20 U2OS 144 666 Large +0.4434005836289967 2.6198752197459624e-39 BR00116996 KCNN4 final crispr A22 U2OS 144 436 Large +0.19894098392221046 8.393523367925795e-39 BR00116996 FFAR4 final crispr G11 U2OS 144 2210 Large +0.20971988685651938 1.039726453597012e-38 BR00116996 SLCO2B1 final crispr I24 U2OS 144 1982 Large +0.2553621788815877 5.753284387434628e-38 BR00116996 TBXAS1 final crispr E24 U2OS 144 1308 Large +0.25113464447806355 5.182884744177622e-37 BR00116996 BTK final crispr P17 U2OS 144 1322 Large +0.3362024621926546 7.420579484835847e-37 BR00116998 FFAR2 final crispr A24 U2OS 144 726 Large +0.3187019862277594 2.562484324237803e-35 BR00116996 CCND1 final crispr B23 U2OS 144 776 Large +0.23497042475490412 3.1889890578494917e-35 BR00116996 S1PR2 final crispr J23 U2OS 144 1434 Large +0.2480190174326466 1.7624197568988761e-34 BR00116996 ICAM1 final crispr I12 U2OS 144 1262 Large +0.18855020095965783 3.955741243608652e-34 BR00116996 KCNMA1 final crispr E23 U2OS 144 2162 Large +0.2443263726879113 8.751464957100746e-34 BR00116996 KDR final crispr O18 U2OS 144 1268 Large +0.19067913096402267 1.0286962338875472e-33 BR00116996 PDE4D final crispr J24 U2OS 144 2094 Large +0.17688483844241923 2.1503734246520653e-33 BR00116996 CCR1 final crispr O17 U2OS 144 2414 Large +0.17466329966329966 4.6318797618587364e-32 BR00116996 CATSPER4 final crispr P02 U2OS 144 2376 Large +0.251141162514828 1.4411429193918027e-31 BR00116996 ITGB2 final crispr D23 U2OS 144 1124 Large +0.23501577287066247 4.086169023357468e-31 BR00116997 S1PR1 final crispr P23 U2OS 144 1268 Large +0.14126074498567334 9.10054945918476e-31 BR00116999 PDE3A final crispr P18 U2OS 144 3490 Large +0.21504693942677466 1.2446545467721426e-30 BR00116996 SCNN1G final crispr P15 U2OS 144 1492 Large +0.19961405301095408 8.266336513273312e-30 BR00116996 JAK1 final crispr M21 U2OS 144 1680 Large +0.339302077449319 2.081174273515504e-29 BR00116996 KCNN1 final crispr B24 U2OS 144 564 Large +0.14164133738601822 3.493458240589289e-29 BR00116998 HIF1A final crispr A01 U2OS 144 3290 Large +0.25614754098360654 1.5577654733178116e-28 BR00116996 HRH4 final crispr H24 U2OS 144 976 Large +0.22894647792002706 7.81993298914517e-28 BR00116996 ANXA1 final crispr F24 U2OS 144 1190 Large +0.16778424068143694 8.347389569131264e-27 BR00116997 TBXAS1 final crispr E24 U2OS 144 2140 Large +0.13408820023837903 1.0487644663421485e-26 BR00116996 PNLIP final crispr C18 U2OS 144 3356 Large +0.17574511819116137 1.171076033613667e-26 BR00116996 ELANE final crispr N19 U2OS 144 1946 Large +0.20525101297303225 1.2003920265697154e-26 BR00116997 GHSR final crispr B20 U2OS 144 1418 Large +0.16635859519408502 1.5007296374316233e-26 BR00116996 SCNN1G final crispr G24 U2OS 144 2164 Large +0.24294354838709678 4.269008362537974e-26 BR00116996 FOXM1 final crispr A19 U2OS 144 992 Large +0.1475484921303085 7.06768066334482e-26 BR00116996 HDAC6 final crispr K12 U2OS 144 2680 Large +0.16525099642699337 1.1686556476684126e-25 BR00116996 PTGIR final crispr G10 U2OS 144 2110 Large +0.1757730812013348 8.387844501639409e-25 BR00116996 FOXM1 final crispr F23 U2OS 144 1800 Large +0.14689530089286848 1.117423516170573e-24 BR00116996 ALK final crispr I15 U2OS 144 2572 Large +0.21661893839452204 5.9669294037959036e-24 BR00116996 GHSR final crispr B20 U2OS 144 1142 Large +0.1890818312846583 1.1404687517420065e-23 BR00116996 KCNQ2 final crispr A16 U2OS 144 1484 Large +0.2546792810542555 1.718385725146335e-23 BR00116996 HPGDS final crispr B19 U2OS 144 804 Large +0.20521172638436483 4.911317953642213e-23 BR00116998 SLCO2B1 final crispr A21 U2OS 144 1228 Large +0.12516457278022003 7.91498500089562e-23 BR00116996 CYP1A2 final crispr K22 U2OS 144 3280 Large +0.16702937976060936 8.56424433346128e-23 BR00116999 AGER final crispr K20 U2OS 144 1838 Large +0.17185697808535177 9.016797410917229e-23 BR00116997 KCNK1 final crispr N20 U2OS 144 1734 Large +0.22745901639344263 1.5464751890515786e-22 BR00116997 CHRM3 final crispr B21 U2OS 144 976 Large +0.14437930231626764 1.622497476406485e-22 BR00116997 VEGFA final crispr C24 U2OS 144 2428 Large +0.19282511210762332 3.695486676762881e-22 BR00116996 SIRT2 final crispr O19 U2OS 144 1338 Large +0.18773538700579284 1.2414399389888445e-21 BR00116996 SLC7A11 final crispr A05 U2OS 144 1376 Large +0.16605668545291186 1.4981794171198314e-21 BR00116999 ADA final crispr O24 U2OS 144 1750 Large +0.1896381731092475 2.0312982561802505e-21 BR00116996 RNASE1 final crispr I13 U2OS 144 1332 Large +0.1636568848758465 4.000207175054456e-21 BR00116998 GRIN2A final crispr A23 U2OS 144 1772 Large +0.23987219451371572 8.715692462617564e-21 BR00116996 KCNMA1 final crispr A07 U2OS 144 802 Large +0.25219175597442445 8.822639601396451e-21 BR00116997 FFAR2 final crispr A24 U2OS 144 728 Large +0.16610327841005607 9.119419952882022e-21 BR00116996 GABRB2 final crispr L22 U2OS 144 1682 Large +0.19676596211976718 2.1159498647909086e-20 BR00116996 GPR119 final crispr G23 U2OS 144 1176 Large +0.13498402555910544 2.690884168186216e-20 BR00116997 HSD11B1 final crispr O23 U2OS 144 2504 Large +0.1476549412575514 3.1967761847561494e-20 BR00116996 CHEK2 final crispr K03 U2OS 144 2082 Large +0.16436604874104874 3.667809787739833e-20 BR00116999 CDK2 final crispr F08 U2OS 144 1664 Large 0.20427807486631017 1.5160914144633877e-34 BR00116999 S1PR1 final crispr P23 U2OS 144 1870 Metaphase 0.19009643956704106 4.998749639486814e-31 BR00116999 CACNA2D3 final crispr N24 U2OS 144 1932 Metaphase 0.17917910432880493 1.5739568784403727e-28 BR00116996 OPRM1 final crispr P22 U2OS 144 2002 Metaphase @@ -1149,6 +11409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.15485921889191645 1.905282895173355e-23 BR00116999 TGFBR1 final crispr P24 U2OS 144 2202 Metaphase 0.13176750776445253 7.00456248456491e-23 BR00116996 IGF1R final crispr M22 U2OS 144 2964 Metaphase 0.1696629213483146 8.849038416593301e-23 BR00116996 CHRM2 final crispr O22 U2OS 144 1780 Metaphase +0.18080939947780678 2.7343842052326647e-22 BR00116996 S1PR1 final crispr P23 U2OS 144 1532 Metaphase +0.1536025336500396 4.270802585639857e-22 BR00116997 TGFBR1 final crispr P24 U2OS 144 2106 Metaphase +0.19490131578947367 1.3173417710678543e-20 BR00116996 S1PR1 final crispr A18 U2OS 144 1216 Metaphase +0.18818040435458788 2.5871540819018463e-20 BR00116996 TGFBR1 final crispr P24 U2OS 144 1286 Metaphase +0.12368712159960034 7.892380935810771e-20 BR00116996 VEGFA final crispr C24 U2OS 144 2900 Metaphase +0.15814748851375768 1.2172256523675354e-19 BR00116996 PDE3A final crispr P18 U2OS 144 1760 Metaphase +0.15580168259413543 4.716887258588873e-19 BR00116999 ADA final crispr O24 U2OS 144 1750 Metaphase +0.14913305043841527 3.135765279443282e-18 BR00116996 OPRM1 final crispr C23 U2OS 144 1828 Metaphase +0.1315016294995675 5.3623566504096795e-18 BR00116996 HPGDS final crispr P14 U2OS 144 2330 Metaphase +0.1539514745236804 1.915325532779273e-17 BR00116996 GRIN2A final crispr A23 U2OS 144 1642 Metaphase +0.12735849056603774 6.799657050764201e-17 BR00116996 ABL1 final crispr P20 U2OS 144 2332 Metaphase +0.1411820681661535 1.9816031755392702e-16 BR00116996 PLD1 final crispr F11 U2OS 144 1832 Metaphase +0.1402985906077656 2.231683579004852e-16 BR00116996 HTR3A final crispr O20 U2OS 144 1856 Metaphase +0.14591048072023102 4.131439336737263e-16 BR00116996 GABRB2 final crispr L22 U2OS 144 1682 Metaphase +0.19997216317441036 5.290566986782876e-16 BR00116997 KCNN1 final crispr B24 U2OS 144 890 Metaphase +0.1574074074074074 1.3666077902976936e-15 BR00116996 CACNA2D3 final crispr N24 U2OS 144 1404 Metaphase +0.1689043276885222 3.702053719166001e-15 BR00116998 CDC25A final crispr D06 U2OS 144 1176 Metaphase +0.10017628813067636 8.542080755750304e-15 BR00116996 CYP1A2 final crispr K22 U2OS 144 3280 Metaphase +0.12476275280760267 8.89019512558534e-15 BR00116996 PTGIR final crispr G10 U2OS 144 2110 Metaphase +0.10848381019172613 1.2006556151776414e-14 BR00116998 PPARD final crispr E05 U2OS 144 2762 Metaphase +0.1837799504697372 1.933750478474373e-14 BR00116999 TUBB final crispr J17 U2OS 144 948 Metaphase +0.11516155758077878 2.339546959663699e-14 BR00116996 CCR1 final crispr O17 U2OS 144 2414 Metaphase +0.16722160735105718 2.3725509656586313e-14 BR00116996 KCNH7 final crispr P16 U2OS 144 1134 Metaphase +0.11706689536878216 2.4684074350703458e-14 BR00116996 P2RY12 final crispr O21 U2OS 144 2332 Metaphase +0.19058706091836183 3.417231038041179e-14 BR00116996 ADA final crispr O24 U2OS 144 862 Metaphase +0.10415979856082394 3.543149313383707e-14 BR00116996 AKR1B1 final crispr L21 U2OS 144 2908 Metaphase +0.12493206144548794 5.733878045281988e-14 BR00116996 SLCO2B1 final crispr I24 U2OS 144 1982 Metaphase +0.1096656086718846 6.233649845784932e-14 BR00116996 ALK final crispr I15 U2OS 144 2572 Metaphase +0.15433137718199677 1.0661312380944434e-13 BR00116996 KDR final crispr O18 U2OS 144 1268 Metaphase +0.12166318715473663 1.5607057454909192e-13 BR00116996 CACNG1 final crispr N23 U2OS 144 2022 Metaphase +0.12720160160363614 5.538443851984013e-13 BR00116996 HIF1A final crispr M24 U2OS 144 1772 Metaphase +0.16287644566586512 7.577100341829046e-13 BR00116996 CHRM3 final crispr B21 U2OS 144 1066 Metaphase +0.14073174851988482 9.105602115534681e-13 BR00116998 HSP90AB1 final crispr B04 U2OS 144 1428 Metaphase +0.12542182227221596 1.3354047342920717e-12 BR00116996 F10 final crispr H07 U2OS 144 1778 Metaphase +0.10806594345237872 3.4740592429193455e-12 BR00116996 GPR55 final crispr C21 U2OS 144 2308 Metaphase +0.12701114576114575 3.917488799008986e-12 BR00116999 CDK2 final crispr F08 U2OS 144 1664 Metaphase +0.11115141561830658 6.427802257689649e-12 BR00116999 PTGIR final crispr G08 U2OS 144 2126 Metaphase +0.12459986378341563 7.508220026679368e-12 BR00116996 JAK1 final crispr M21 U2OS 144 1680 Metaphase +0.11982227998568894 7.888329899114329e-12 BR00116999 LCK final crispr O15 U2OS 144 1812 Metaphase +0.10840965281888777 8.817600458236621e-12 BR00116996 FFAR4 final crispr G11 U2OS 144 2210 Metaphase +0.11630321910695743 9.207364876564029e-12 BR00116996 PRKCE final crispr K05 U2OS 144 1926 Metaphase +0.11266110806796541 9.580034016418228e-12 BR00116996 FPR1 final crispr N22 U2OS 144 2038 Metaphase +0.11314571335858911 1.0039627173942253e-11 BR00116996 KCNK1 final crispr N20 U2OS 144 2022 Metaphase +0.21326806000125526 1.1132385074476452e-11 BR00116996 KCNN1 final crispr B24 U2OS 144 564 Metaphase +0.13075068827064226 1.4316607310475475e-11 BR00116996 SCNN1G final crispr P15 U2OS 144 1492 Metaphase +0.13197494196656484 1.563521657828633e-11 BR00116996 PORCN final crispr L13 U2OS 144 1458 Metaphase +0.13923470423166012 1.5876756083153555e-11 BR00116996 TBXAS1 final crispr E24 U2OS 144 1308 Metaphase +0.11474558670820353 1.8468681201819106e-11 BR00116996 ATP5F1D final crispr G21 U2OS 144 1926 Metaphase +0.10585104685305757 2.2072151228009853e-11 BR00116996 PDPK1 final crispr N18 U2OS 144 2238 Metaphase +0.1125685485639963 2.470988074771475e-11 BR00116996 DYRK1B final crispr K14 U2OS 144 1970 Metaphase +0.13373463527709878 4.622254587692808e-11 BR00116996 ITGB2 final crispr A17 U2OS 144 1356 Metaphase +0.12098792281037507 4.7429042856079635e-11 BR00116999 P2RY12 final crispr P19 U2OS 144 1660 Metaphase +0.11133810010214505 5.505330374828954e-11 BR00116996 KCNQ2 final crispr P13 U2OS 144 1958 Metaphase +0.15332681251043728 9.755417286154533e-11 BR00116998 AVPR1A final crispr J07 U2OS 144 1004 Metaphase +0.10904522613065326 1.0151581425022563e-10 BR00116999 HPGDS final crispr P14 U2OS 144 1990 Metaphase +0.20058853264009244 1.0468739897237186e-10 BR00116998 CDK9 final crispr I20 U2OS 144 576 Metaphase +0.09512335272693996 1.0992542524066926e-10 BR00116999 TUBB4B final crispr C04 U2OS 144 2596 Metaphase +0.18875353344999327 1.6681682291506508e-10 BR00116998 TGFBR1 final crispr B08 U2OS 144 646 Metaphase +0.10921877383850734 1.6948448391009834e-10 BR00116998 PARP3 final crispr F12 U2OS 144 1928 Metaphase +0.12349799732977303 2.2730392431489807e-10 BR00116996 P2RY12 final crispr P19 U2OS 144 1498 Metaphase +0.11476355247981546 2.310077629517434e-10 BR00116997 KCNK1 final crispr N20 U2OS 144 1734 Metaphase +0.12303773403151258 2.908028546722561e-10 BR00116996 KCNQ2 final crispr A16 U2OS 144 1484 Metaphase +0.1209352523492296 3.2322100915741387e-10 BR00116996 BAX final crispr E06 U2OS 144 1534 Metaphase +0.0958081413857964 3.53073346992995e-10 BR00116999 HDAC3 final crispr G07 U2OS 144 2428 Metaphase +0.1317411063330727 3.546988822237504e-10 BR00116996 GPR119 final crispr P21 U2OS 144 1280 Metaphase +0.12929745889387145 3.655450227527317e-10 BR00116996 SIRT2 final crispr O19 U2OS 144 1338 Metaphase +0.1019973584438833 6.073116397800764e-10 BR00116996 IGF1R final crispr E19 U2OS 144 2096 Metaphase +0.13236376976795985 6.384824730235445e-10 BR00116998 GAA final crispr L17 U2OS 144 1236 Metaphase +0.10026759451096115 6.823317474830921e-10 BR00116999 CA5A final crispr I02 U2OS 144 2156 Metaphase +0.12903225806451613 7.311253415106931e-10 BR00116997 BTK final crispr D24 U2OS 144 1302 Metaphase +0.21175758438968809 8.199607343730125e-10 BR00116997 AURKB final crispr C13 U2OS 144 476 Metaphase +0.2109527355245896 8.548514184298576e-10 BR00116996 TUBB3 final crispr K11 U2OS 144 476 Metaphase +0.2349213631345787 1.317006152795087e-09 BR00116998 TUBB3 final crispr K11 U2OS 144 374 Metaphase +0.08343281032961862 1.8387569431443925e-09 BR00116999 CCR1 final crispr O17 U2OS 144 2968 Metaphase +0.07342469058387097 1.9545519876288016e-09 BR00116996 TNF final crispr I10 U2OS 144 3836 Metaphase +0.1588570224840926 2.2287439207078536e-09 BR00116996 HPGDS final crispr B19 U2OS 144 804 Metaphase +0.10595477368659673 2.50378725573267e-09 BR00116996 USP1 final crispr K18 U2OS 144 1816 Metaphase +0.12405446293494705 2.79191213308681e-09 BR00116996 BTK final crispr P17 U2OS 144 1322 Metaphase +0.10948205084649794 3.048723388645496e-09 BR00116996 PIK3CG final crispr E22 U2OS 144 1682 Metaphase +0.10311297210359936 3.112340786797e-09 BR00116996 KCNH7 final crispr O16 U2OS 144 1898 Metaphase +0.1079176853460293 3.3667937532701325e-09 BR00116997 ADH1C final crispr P04 U2OS 144 1728 Metaphase +0.11861986173779857 3.3806675531306463e-09 BR00116997 GRIN2A final crispr P09 U2OS 144 1428 Metaphase +0.11489082683102747 3.6684392275407117e-09 BR00116998 PORCN final crispr L13 U2OS 144 1510 Metaphase +0.11795303632360551 3.76091365937732e-09 BR00116996 S1PR2 final crispr J23 U2OS 144 1434 Metaphase +0.098922624877571 4.080585515342755e-09 BR00116998 AKR1C1 final crispr B06 U2OS 144 2042 Metaphase +0.1329189402926058 4.088724140367584e-09 BR00116996 ITGB2 final crispr D23 U2OS 144 1124 Metaphase +0.08286812952537367 5.952142627454091e-09 BR00116998 AKT1 final crispr F06 U2OS 144 2848 Metaphase +0.15602142652169754 6.845689200842768e-09 BR00116996 FFAR2 final crispr A24 U2OS 144 794 Metaphase +0.11265242772626008 7.242059439946342e-09 BR00116997 PDE4D final crispr J24 U2OS 144 1514 Metaphase +0.09726295210166178 7.653814088819755e-09 BR00116999 CDC25A final crispr D06 U2OS 144 2046 Metaphase 0.1757674469696307 6.757085413100554e-28 BR00116996 BTK final crispr D24 U2OS 144 2028 MetaphaseAlignment 0.14502741730204233 4.579359834222523e-27 BR00116996 VEGFA final crispr C24 U2OS 144 2900 MetaphaseAlignment 0.1545045799821269 9.151131535889551e-24 BR00116996 PDPK1 final crispr N18 U2OS 144 2238 MetaphaseAlignment @@ -1159,6 +11509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.15215633712458174 5.121522754227849e-19 BR00116996 PLD1 final crispr F11 U2OS 144 1832 MetaphaseAlignment 0.13833003201628877 6.03942933503137e-19 BR00116996 FFAR4 final crispr G11 U2OS 144 2210 MetaphaseAlignment 0.15120554419845447 4.4754265296680993e-17 BR00116999 ADH1C final crispr P04 U2OS 144 1660 MetaphaseAlignment +0.12906777234809222 8.80971459870806e-17 BR00116999 DNMT3A final crispr L04 U2OS 144 2250 MetaphaseAlignment +0.11863848602823351 3.1547987476804933e-16 BR00116996 ALK final crispr I15 U2OS 144 2572 MetaphaseAlignment +0.15235493464278305 7.528962052326016e-16 BR00116996 TNNC1 final crispr D09 U2OS 144 1520 MetaphaseAlignment +0.21189746447478405 8.515500373436163e-16 BR00116996 CCND1 final crispr B23 U2OS 144 776 MetaphaseAlignment +0.25862068965517243 9.538196459226445e-16 BR00116996 PLA2G1B final crispr J11 U2OS 144 522 MetaphaseAlignment +0.15391247363932867 1.559597409873703e-15 BR00116996 PORCN final crispr L13 U2OS 144 1458 MetaphaseAlignment +0.15716445186472036 1.640507303651251e-15 BR00116996 CDK9 final crispr I20 U2OS 144 1396 MetaphaseAlignment +0.10135005467163546 4.325308604675418e-15 BR00116996 CYP1A2 final crispr K22 U2OS 144 3280 MetaphaseAlignment +0.17624472168066932 5.490462180460952e-15 BR00116998 LYN final crispr N13 U2OS 144 1070 MetaphaseAlignment +0.13433137031567577 7.783816519130644e-15 BR00116996 OPRM1 final crispr C23 U2OS 144 1828 MetaphaseAlignment +0.1859007705201567 9.148043102728947e-15 BR00116999 TUBB final crispr J17 U2OS 144 948 MetaphaseAlignment +0.13448791273799335 9.313763705377205e-15 BR00116996 USP1 final crispr K18 U2OS 144 1816 MetaphaseAlignment +0.14944738060427679 1.7711425311069227e-14 BR00116996 ADRA2B final crispr J14 U2OS 144 1442 MetaphaseAlignment +0.1432225063938619 2.1112222963116422e-14 BR00116999 GUCY1B1 final crispr H21 U2OS 144 1564 MetaphaseAlignment +0.14557090925323 5.194842370723983e-14 BR00116996 PIK3CG final crispr I08 U2OS 144 1466 MetaphaseAlignment +0.1025384519194698 9.299504314871818e-14 BR00116996 AKR1B1 final crispr L21 U2OS 144 2908 MetaphaseAlignment +0.13153473342001754 9.858174722900231e-14 BR00116996 HDAC3 final crispr G07 U2OS 144 1754 MetaphaseAlignment +0.09670367977938094 1.5871415653100792e-13 BR00116998 ALDH2 final crispr A10 U2OS 144 3212 MetaphaseAlignment +0.1490844391726592 3.30652675524385e-13 BR00116996 AKT1 final crispr J19 U2OS 144 1312 MetaphaseAlignment +0.16821260490754256 5.077449317981637e-13 BR00116996 CSF1R final crispr J15 U2OS 144 1018 MetaphaseAlignment +0.13055820886270333 5.544204401332944e-13 BR00116998 TUBB final crispr K13 U2OS 144 1684 MetaphaseAlignment +0.12416091025569606 6.159303237490856e-13 BR00116996 HTR3A final crispr O20 U2OS 144 1856 MetaphaseAlignment +0.10300440889050498 6.36013840271911e-13 BR00116997 UGT1A9 final crispr B18 U2OS 144 2694 MetaphaseAlignment +0.11335125448028674 6.643386257531577e-13 BR00116997 CDK4 final crispr P03 U2OS 144 2232 MetaphaseAlignment +0.11034942599678133 8.842482206259029e-13 BR00116996 HCK final crispr M23 U2OS 144 2316 MetaphaseAlignment +0.11810886679959436 8.862087228726567e-13 BR00116999 HIF1A final crispr M24 U2OS 144 2020 MetaphaseAlignment +0.1106806085448171 8.877300561097677e-13 BR00116996 GPR55 final crispr C21 U2OS 144 2308 MetaphaseAlignment +0.13505613167359445 9.748561018390183e-13 BR00116996 DCK final crispr J08 U2OS 144 1538 MetaphaseAlignment +0.12295973884657237 1.6038907749349813e-12 BR00116999 AGER final crispr K20 U2OS 144 1838 MetaphaseAlignment +0.09915018052817327 1.774077161692512e-12 BR00116999 LPAR1 final crispr B16 U2OS 144 2804 MetaphaseAlignment +0.10144542509715153 1.7992245548522888e-12 BR00116996 HDAC6 final crispr K12 U2OS 144 2680 MetaphaseAlignment +0.15889915156642928 1.8078667961195514e-12 BR00116998 CATSPER4 final crispr P02 U2OS 144 1092 MetaphaseAlignment +0.2085987261146497 2.2665470690272154e-12 BR00116996 TUBB4B final crispr J13 U2OS 144 628 MetaphaseAlignment +0.10849056603773585 2.288448676013305e-12 BR00116996 ABL1 final crispr P20 U2OS 144 2332 MetaphaseAlignment +0.10806174957118353 2.844057609372305e-12 BR00116996 P2RY12 final crispr O21 U2OS 144 2332 MetaphaseAlignment +0.16889181839174777 3.0184206651640712e-12 BR00116996 CDK7 final crispr I14 U2OS 144 942 MetaphaseAlignment +0.1242070787867211 3.5603256862068622e-12 BR00116999 S1PR2 final crispr K02 U2OS 144 1736 MetaphaseAlignment +0.11344137273593899 3.5729386790600456e-12 BR00116997 ALDH2 final crispr A10 U2OS 144 2098 MetaphaseAlignment +0.15345195729537367 4.619088894720157e-12 BR00116996 ITGB2 final crispr D23 U2OS 144 1124 MetaphaseAlignment +0.11920529032737266 6.3024475447964865e-12 BR00116996 CYP2A6 final crispr C07 U2OS 144 1856 MetaphaseAlignment +0.11384112704910021 6.679806166000045e-12 BR00116996 CACNG1 final crispr N23 U2OS 144 2022 MetaphaseAlignment +0.11545922267112861 1.0360169363030933e-11 BR00116997 ADA final crispr O06 U2OS 144 1934 MetaphaseAlignment +0.14647933087959306 1.147769937705157e-11 BR00116998 ATM final crispr G12 U2OS 144 1194 MetaphaseAlignment +0.18979494515975204 1.5661327020529955e-11 BR00116997 PLA2G1B final crispr J11 U2OS 144 702 MetaphaseAlignment +0.08887507768800497 1.7748346214227276e-11 BR00116999 CATSPER4 final crispr A02 U2OS 144 3218 MetaphaseAlignment +0.1141956039004924 1.974011834196125e-11 BR00116999 JAK1 final crispr M21 U2OS 144 1932 MetaphaseAlignment +0.14516129032258066 3.070157116455995e-11 BR00116996 PPAT final crispr G13 U2OS 144 1178 MetaphaseAlignment +0.11018609206660138 3.272020403631427e-11 BR00116998 AKR1C1 final crispr B06 U2OS 144 2042 MetaphaseAlignment +0.121631006006006 3.576069507687084e-11 BR00116999 CDK2 final crispr F08 U2OS 144 1664 MetaphaseAlignment +0.13431430240333087 3.9052731666898255e-11 BR00116999 PAK4 final crispr M16 U2OS 144 1358 MetaphaseAlignment +0.09584622187927973 4.004266840027771e-11 BR00116997 HRH4 final crispr A08 U2OS 144 2664 MetaphaseAlignment +0.13586011863705338 4.110840737553593e-11 BR00116998 HTR2C final crispr L03 U2OS 144 1318 MetaphaseAlignment +0.08551847437425507 4.269285546056456e-11 BR00116996 PNLIP final crispr C18 U2OS 144 3356 MetaphaseAlignment +0.13869157935877555 4.4746714858568237e-11 BR00116996 PARP3 final crispr F12 U2OS 144 1260 MetaphaseAlignment +0.11073783416215267 5.620571216364543e-11 BR00116996 ALK final crispr G06 U2OS 144 1970 MetaphaseAlignment +0.11914878377216859 8.14933663292836e-11 BR00116999 VEGFA final crispr H02 U2OS 144 1672 MetaphaseAlignment +0.10873882820258193 8.728322180367845e-11 BR00116998 PRKCB final crispr N04 U2OS 144 2014 MetaphaseAlignment +0.15175876524390244 9.361283128479036e-11 BR00116999 FLT3 final crispr G16 U2OS 144 1024 MetaphaseAlignment +0.0891861068335836 1.0877214992842596e-10 BR00116996 IGF1R final crispr M22 U2OS 144 2964 MetaphaseAlignment +0.13766974068277 1.2130984730196336e-10 BR00116996 AKR1B1 final crispr H17 U2OS 144 1228 MetaphaseAlignment +0.11873094054784533 1.44292795395699e-10 BR00116996 GRIN2A final crispr A23 U2OS 144 1642 MetaphaseAlignment +0.14274868545613031 1.5441281401766857e-10 BR00116998 DYRK1B final crispr K14 U2OS 144 1132 MetaphaseAlignment +0.16999101527403415 1.6001068715886307e-10 BR00116996 RPL3 final crispr H11 U2OS 144 798 MetaphaseAlignment +0.1144565329616437 1.6535077239909403e-10 BR00116996 PDE3A final crispr P18 U2OS 144 1760 MetaphaseAlignment +0.10795480602864231 2.091964991932544e-10 BR00116999 ADA final crispr O06 U2OS 144 1960 MetaphaseAlignment +0.12484045164457536 2.1902883085036204e-10 BR00116999 CLK1 final crispr N05 U2OS 144 1456 MetaphaseAlignment +0.11227165986899024 2.46603262244613e-10 BR00116996 FOXM1 final crispr F23 U2OS 144 1800 MetaphaseAlignment +0.09842288049783195 2.8728425819388403e-10 BR00116996 HPGDS final crispr P14 U2OS 144 2330 MetaphaseAlignment +0.08022922636103152 3.4345352379844393e-10 BR00116999 PDE3A final crispr P18 U2OS 144 3490 MetaphaseAlignment +0.1493335010060362 3.655811288310207e-10 BR00116996 EZH2 final crispr H09 U2OS 144 994 MetaphaseAlignment +0.09539473684210527 4.750737429054873e-10 BR00116996 EDNRB final crispr K06 U2OS 144 2432 MetaphaseAlignment +0.14150240227233812 5.599446852765537e-10 BR00116998 CYP2A6 final crispr O04 U2OS 144 1092 MetaphaseAlignment +0.12694960053726384 6.351281602848976e-10 BR00116999 DYRK1B final crispr N16 U2OS 144 1346 MetaphaseAlignment +0.10573978913323333 6.636276875719181e-10 BR00116996 CASP3 final crispr E11 U2OS 144 1938 MetaphaseAlignment +0.12517125874526597 6.740758861165121e-10 BR00116999 CDC25A final crispr C14 U2OS 144 1386 MetaphaseAlignment +0.12277589857822511 7.303092890385731e-10 BR00116998 HSP90AB1 final crispr B04 U2OS 144 1428 MetaphaseAlignment +0.12430873558041187 8.143408984197479e-10 BR00116997 S1PR2 final crispr K02 U2OS 144 1384 MetaphaseAlignment +0.10123934668037865 8.512962129794309e-10 BR00116999 CACNB4 final crispr B01 U2OS 144 2090 MetaphaseAlignment +0.08829334038054969 8.932485968760446e-10 BR00116999 CYP2A6 final crispr O04 U2OS 144 2752 MetaphaseAlignment +0.0940347970173985 1.0443387836237663e-09 BR00116996 CCR1 final crispr O17 U2OS 144 2414 MetaphaseAlignment +0.1447582921805791 1.1412070857842334e-09 BR00116998 AVPR1A final crispr J07 U2OS 144 1004 MetaphaseAlignment +0.12038303693570451 1.2030042673937266e-09 BR00116997 CLK1 final crispr M11 U2OS 144 1462 MetaphaseAlignment +0.13348696059518925 1.3910664453874752e-09 BR00116999 CTSG final crispr G18 U2OS 144 1172 MetaphaseAlignment +0.16153429200012753 1.689773101141262e-09 BR00116996 FFAR2 final crispr A24 U2OS 144 794 MetaphaseAlignment +0.10233029381965553 2.0436320238532002e-09 BR00116996 BRAF final crispr J10 U2OS 144 1974 MetaphaseAlignment +0.11665290635375129 2.0541254606922173e-09 BR00116996 AGER final crispr K20 U2OS 144 1508 MetaphaseAlignment +0.1540575703366401 2.133381735564416e-09 BR00116996 ELANE final crispr H10 U2OS 144 860 MetaphaseAlignment +0.1152183471663388 2.3004118889043987e-09 BR00116996 BAX final crispr E06 U2OS 144 1534 MetaphaseAlignment +0.12215055197801986 2.370100521901318e-09 BR00116999 PPAT final crispr E13 U2OS 144 1364 MetaphaseAlignment +0.10643015521064302 2.5825154827327864e-09 BR00116999 BAX final crispr E06 U2OS 144 1804 MetaphaseAlignment 0.43402417962003453 4.270975408871048e-164 BR00116999 CACNA2D3 final crispr N24 U2OS 144 1932 OutOfFocus 0.4223585795442083 1.2302711364198838e-160 BR00116996 OPRM1 final crispr P22 U2OS 144 2002 OutOfFocus 0.38850771869639794 2.3530338761381272e-157 BR00116996 ABL1 final crispr P20 U2OS 144 2332 OutOfFocus @@ -1169,6 +11609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.38096010739973507 1.2032607529686845e-106 BR00116996 GRIN2A final crispr A23 U2OS 144 1642 OutOfFocus 0.3532389791350027 6.777026846295802e-102 BR00116996 OPRM1 final crispr C23 U2OS 144 1828 OutOfFocus 0.381201044386423 1.4538785309177727e-99 BR00116996 S1PR1 final crispr P23 U2OS 144 1532 OutOfFocus +0.331021684587291 8.08005456067295e-99 BR00116996 BTK final crispr D24 U2OS 144 2028 OutOfFocus +0.3251813963751076 5.741092174874922e-96 BR00116996 FPR1 final crispr N22 U2OS 144 2038 OutOfFocus +0.2677926546161088 4.683388793172496e-94 BR00116996 IGF1R final crispr M22 U2OS 144 2964 OutOfFocus +0.37316421895861146 3.2437526719014743e-93 BR00116996 P2RY12 final crispr P19 U2OS 144 1498 OutOfFocus +0.3599246231155779 5.272488315479785e-92 BR00116996 HSD11B1 final crispr O23 U2OS 144 1592 OutOfFocus +0.3272113438434256 2.3019751955991233e-88 BR00116996 HTR3A final crispr O20 U2OS 144 1856 OutOfFocus +0.35037406483790523 9.347461520131375e-88 BR00116996 SLCO2B1 final crispr A21 U2OS 144 1604 OutOfFocus +0.2859692160445099 7.427087259493313e-84 BR00116996 HCK final crispr M23 U2OS 144 2316 OutOfFocus +0.353988603988604 1.7463053160561726e-78 BR00116996 CACNA2D3 final crispr N24 U2OS 144 1404 OutOfFocus +0.2755755812988412 2.08964711973336e-78 BR00116996 HPGDS final crispr P14 U2OS 144 2330 OutOfFocus +0.306951871657754 3.5867763183848455e-78 BR00116999 S1PR1 final crispr P23 U2OS 144 1870 OutOfFocus +0.24227331660144402 4.2745386184025565e-75 BR00116996 VEGFA final crispr C24 U2OS 144 2900 OutOfFocus +0.43443317325851183 1.2147040681688115e-73 BR00116996 ADA final crispr O24 U2OS 144 862 OutOfFocus +0.30291116358892345 2.2860769450665155e-72 BR00116996 HIF1A final crispr M24 U2OS 144 1772 OutOfFocus +0.3719036566933007 1.8710512376625804e-70 BR00116996 KCNH7 final crispr P16 U2OS 144 1134 OutOfFocus +0.42965915250454356 2.843114674840815e-66 BR00116996 FFAR2 final crispr A24 U2OS 144 794 OutOfFocus +0.26751436647870624 4.047299695058029e-64 BR00116999 HIF1A final crispr M24 U2OS 144 2020 OutOfFocus +0.2636886954829712 4.663362698985897e-61 BR00116996 SLCO2B1 final crispr I24 U2OS 144 1982 OutOfFocus +0.24795640326975477 7.95023814775721e-60 BR00116999 TGFBR1 final crispr P24 U2OS 144 2202 OutOfFocus +0.25793006181020633 1.4212855501376063e-59 BR00116996 CACNG1 final crispr N23 U2OS 144 2022 OutOfFocus +0.31386214816262703 2.457695487506054e-56 BR00116996 GPR119 final crispr P21 U2OS 144 1280 OutOfFocus +0.20541841448118803 4.083052497738556e-54 BR00116996 AKR1B1 final crispr L21 U2OS 144 2908 OutOfFocus +0.24225173291422808 1.173299502165043e-52 BR00116996 KCNK1 final crispr N20 U2OS 144 2022 OutOfFocus +0.3242484299165852 5.037494254745364e-50 BR00116996 CHRM3 final crispr B21 U2OS 144 1066 OutOfFocus +0.2806354009077156 3.0825048051733696e-46 BR00116996 BTK final crispr P17 U2OS 144 1322 OutOfFocus +0.21606754760963479 1.3781243053458635e-45 BR00116996 FFAR4 final crispr G11 U2OS 144 2210 OutOfFocus +0.20546810273405136 5.4162169719498765e-45 BR00116996 CCR1 final crispr O17 U2OS 144 2414 OutOfFocus +0.2089881880337133 1.5076579073016404e-44 BR00116996 GPR55 final crispr C21 U2OS 144 2308 OutOfFocus +0.3153061224489796 1.9056671795279988e-43 BR00116996 ADORA2A final crispr B22 U2OS 144 980 OutOfFocus +0.28125 9.468666927127721e-43 BR00116996 S1PR1 final crispr A18 U2OS 144 1216 OutOfFocus +0.27416798732171155 3.8689438154701047e-42 BR00116996 ICAM1 final crispr I12 U2OS 144 1262 OutOfFocus +0.169384442014594 1.525817498794232e-41 BR00116996 CYP1A2 final crispr K22 U2OS 144 3280 OutOfFocus +0.1910961960012519 1.7465455741523743e-41 BR00116996 ALK final crispr I15 U2OS 144 2572 OutOfFocus +0.2578444446081646 1.0947785534224514e-40 BR00116996 SLC29A1 final crispr N21 U2OS 144 1378 OutOfFocus +0.18500732317948643 7.495525944504118e-40 BR00116997 CACNA2D3 final crispr N24 U2OS 144 2630 OutOfFocus +0.20645326002466416 1.7478197807073245e-39 BR00116996 PDE4D final crispr J24 U2OS 144 2094 OutOfFocus +0.26316293985394845 3.4415955153653314e-39 BR00116996 KDR final crispr O18 U2OS 144 1268 OutOfFocus +0.19508514240632563 3.524538894715683e-39 BR00116996 PDE7A final crispr C22 U2OS 144 2328 OutOfFocus +0.17496542185338865 4.570745754498674e-39 BR00116996 ASIC1 final crispr M20 U2OS 144 2892 OutOfFocus +0.2586750788643533 1.1112754447447389e-37 BR00116997 S1PR1 final crispr P23 U2OS 144 1268 OutOfFocus +0.19869774786191552 5.773725754813485e-37 BR00116996 PTGIR final crispr G10 U2OS 144 2110 OutOfFocus +0.21653543307086615 6.570914216992062e-37 BR00116996 F10 final crispr H07 U2OS 144 1778 OutOfFocus +0.3506455557353761 7.872962041205475e-37 BR00116996 MAPK14 final crispr A20 U2OS 144 666 OutOfFocus +0.24363298083249457 7.167191319614512e-36 BR00116996 ITGB2 final crispr A17 U2OS 144 1356 OutOfFocus +0.3212030145019836 7.605678791593201e-36 BR00116996 CCND1 final crispr B23 U2OS 144 776 OutOfFocus +0.1524355300859599 8.892802124587516e-36 BR00116999 PDE3A final crispr P18 U2OS 144 3490 OutOfFocus +0.19773625222258637 4.125949920582973e-34 BR00116996 DYRK1B final crispr K14 U2OS 144 1970 OutOfFocus +0.22949103678558166 1.2755410464982801e-33 BR00116996 S1PR2 final crispr J23 U2OS 144 1434 OutOfFocus +0.23787080385447065 5.412260918477812e-33 BR00116996 TBXAS1 final crispr E24 U2OS 144 1308 OutOfFocus +0.18736874397998704 8.602785236696273e-33 BR00116997 TGFBR1 final crispr P24 U2OS 144 2106 OutOfFocus +0.1932168550873587 3.6198406823654595e-32 BR00116996 ELANE final crispr N19 U2OS 144 1946 OutOfFocus +0.18207024029574861 9.538759639061213e-32 BR00116996 SCNN1G final crispr G24 U2OS 144 2164 OutOfFocus +0.18794688457609807 1.2351166920283896e-30 BR00116996 KCNQ2 final crispr P13 U2OS 144 1958 OutOfFocus +0.17508258330141707 1.861438360625333e-30 BR00116996 PDPK1 final crispr N18 U2OS 144 2238 OutOfFocus +0.20059311477266292 3.929705197311064e-30 BR00116996 GABRB2 final crispr L22 U2OS 144 1682 OutOfFocus +0.2610887096774194 4.0309313641834176e-30 BR00116996 FOXM1 final crispr A19 U2OS 144 992 OutOfFocus +0.38822874897654985 8.78947196272641e-30 BR00116996 KCNN4 final crispr A22 U2OS 144 436 OutOfFocus +0.143744390580212 2.1312646036051855e-29 BR00116998 ALDH2 final crispr A10 U2OS 144 3212 OutOfFocus +0.15714879097229578 2.401462170614791e-29 BR00116996 HDAC6 final crispr K12 U2OS 144 2680 OutOfFocus +0.1394517282479142 7.398921525590363e-29 BR00116996 PNLIP final crispr C18 U2OS 144 3356 OutOfFocus +0.16540404040404041 8.833063501151449e-29 BR00116996 CATSPER4 final crispr P02 U2OS 144 2376 OutOfFocus +0.2577329900895013 3.9899803269488517e-28 BR00116999 TUBB final crispr J17 U2OS 144 948 OutOfFocus +0.2074141767996006 5.754384751258203e-28 BR00116996 PORCN final crispr L13 U2OS 144 1458 OutOfFocus +0.21585296791908362 1.366303547535481e-27 BR00116996 RNASE1 final crispr I13 U2OS 144 1332 OutOfFocus +0.20363969121491363 3.618514448460323e-27 BR00116996 PIK3CG final crispr I08 U2OS 144 1466 OutOfFocus +0.25986435874076325 6.68592345124778e-27 BR00116997 KCNN1 final crispr B24 U2OS 144 890 OutOfFocus +0.152555910543131 7.905796057449849e-26 BR00116997 HSD11B1 final crispr O23 U2OS 144 2504 OutOfFocus +0.16357461191819836 9.00763607993062e-26 BR00116996 KCNMA1 final crispr E23 U2OS 144 2162 OutOfFocus +0.20929387979810596 9.256353195682539e-26 BR00116996 GLRA3 final crispr F16 U2OS 144 1314 OutOfFocus +0.19999595749984841 1.1578622018125922e-25 BR00116996 ADRA2B final crispr J14 U2OS 144 1442 OutOfFocus +0.2062780269058296 2.5497311989990834e-25 BR00116996 SIRT2 final crispr O19 U2OS 144 1338 OutOfFocus +0.17601997619836918 3.2801862372275077e-25 BR00116996 PLD1 final crispr F11 U2OS 144 1832 OutOfFocus +0.22362514827995256 4.339701025175245e-25 BR00116996 ITGB2 final crispr D23 U2OS 144 1124 OutOfFocus +0.19397873617824543 5.279425704025153e-25 BR00116996 SCNN1G final crispr P15 U2OS 144 1492 OutOfFocus +0.18649301878081803 7.89917850064412e-25 BR00116996 TUBB final crispr K13 U2OS 144 1606 OutOfFocus +0.2387295081967213 8.350750236907917e-25 BR00116996 HRH4 final crispr H24 U2OS 144 976 OutOfFocus +0.2583564122104298 3.5985934253705595e-24 BR00116996 HPGDS final crispr B19 U2OS 144 804 OutOfFocus +0.3055670620724283 9.145569824682624e-24 BR00116996 KCNN1 final crispr B24 U2OS 144 564 OutOfFocus +0.18378311829016053 1.760088466409706e-23 BR00116996 RET final crispr I03 U2OS 144 1562 OutOfFocus +0.1656282450674974 1.798295937595173e-23 BR00116996 ATP5F1D final crispr G21 U2OS 144 1926 OutOfFocus +0.18579673763620252 2.246460323764915e-23 BR00116996 PTGIS final crispr I16 U2OS 144 1518 OutOfFocus +0.187099799524894 3.062232661856226e-23 BR00116996 KCNQ2 final crispr A16 U2OS 144 1484 OutOfFocus +0.17569385322663034 4.1284441709853174e-23 BR00116996 JAK1 final crispr M21 U2OS 144 1680 OutOfFocus +0.16702937976060936 8.56424433346128e-23 BR00116999 AGER final crispr K20 U2OS 144 1838 OutOfFocus +0.20066539668911487 5.309888752364455e-22 BR00116997 GRIN2A final crispr A23 U2OS 144 1222 OutOfFocus +0.15760778851085397 5.6086570522939425e-22 BR00116996 PTGIR final crispr G08 U2OS 144 1988 OutOfFocus +0.21009099363238315 6.007125095744759e-22 BR00116996 PRKCE final crispr I17 U2OS 144 1114 OutOfFocus +0.163571869978989 1.5991775550411881e-21 BR00116996 FOXM1 final crispr F23 U2OS 144 1800 OutOfFocus +0.16262464875296695 2.1543893546388403e-21 BR00116996 USP1 final crispr K18 U2OS 144 1816 OutOfFocus +0.20043144774688398 2.182814351226636e-21 BR00116996 ANXA1 final crispr F24 U2OS 144 1190 OutOfFocus 0.22979397781299524 1.291411884199797e-29 BR00116996 ICAM1 final crispr I12 U2OS 144 1262 Polylobed 0.17875567583646593 7.360415504617031e-29 BR00116996 BTK final crispr D24 U2OS 144 2028 Polylobed 0.1807257912516492 3.106568130295097e-24 BR00116999 ADH1C final crispr P04 U2OS 144 1660 Polylobed @@ -1179,6 +11709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.172133273393734 4.028540007028417e-20 BR00116996 TNNC1 final crispr D09 U2OS 144 1520 Polylobed 0.11833740679434664 4.9763351896301825e-20 BR00116998 ALDH2 final crispr A10 U2OS 144 3212 Polylobed 0.28735632183908044 2.1558171266624548e-19 BR00116996 PLA2G1B final crispr J11 U2OS 144 522 Polylobed +0.14890720912257713 3.9270245600268193e-19 BR00116997 ADA final crispr O06 U2OS 144 1934 Polylobed +0.146749798063995 5.619728566580072e-19 BR00116996 DYRK1B final crispr K14 U2OS 144 1970 Polylobed +0.1350771869639794 5.881494225765451e-19 BR00116996 ABL1 final crispr P20 U2OS 144 2332 Polylobed +0.1193075244125638 1.812007290367004e-18 BR00116996 AKR1B1 final crispr L21 U2OS 144 2908 Polylobed +0.11107784431137725 2.3416159413038023e-18 BR00116999 ANXA1 final crispr G01 U2OS 144 3340 Polylobed +0.1377551020408163 3.0210393973788273e-18 BR00116997 DYRK1B final crispr K14 U2OS 144 2156 Polylobed +0.11187072715972654 5.9779992568714585e-18 BR00116999 CATSPER4 final crispr A02 U2OS 144 3218 Polylobed +0.16486478609190766 9.525555004626116e-18 BR00116996 PORCN final crispr L13 U2OS 144 1458 Polylobed +0.14512016507901138 1.7704890798094803e-17 BR00116996 CYP2A6 final crispr C07 U2OS 144 1856 Polylobed +0.15919022496747454 1.1659214415029925e-16 BR00116996 PIK3CG final crispr I08 U2OS 144 1466 Polylobed +0.16457999416967123 1.359146214143928e-16 BR00116999 PAK4 final crispr M16 U2OS 144 1358 Polylobed +0.14405619224614113 1.8840723646694685e-16 BR00116996 PDE3A final crispr P18 U2OS 144 1760 Polylobed +0.1360581575694389 2.259653172365525e-16 BR00116996 ALK final crispr G06 U2OS 144 1970 Polylobed +0.13397929415893486 3.700780636614085e-16 BR00116996 OPRM1 final crispr P22 U2OS 144 2002 Polylobed +0.1274596518971136 3.776442145918985e-16 BR00116996 FFAR4 final crispr G11 U2OS 144 2210 Polylobed +0.12327707721630987 7.757184176240603e-16 BR00116996 HCK final crispr M23 U2OS 144 2316 Polylobed +0.1923299231258309 8.913294788171596e-16 BR00116999 TUBB final crispr J17 U2OS 144 948 Polylobed +0.10168471720818291 2.2438886548468242e-15 BR00116997 HDAC6 final crispr L10 U2OS 144 3324 Polylobed +0.13200371057513915 2.455405449028441e-15 BR00116999 ADA final crispr O06 U2OS 144 1960 Polylobed +0.11262297994719249 2.5221903458951094e-15 BR00116997 UGT1A9 final crispr B18 U2OS 144 2694 Polylobed +0.14988992102451396 1.0967598061361626e-14 BR00116997 PTGIR final crispr G10 U2OS 144 1448 Polylobed +0.1330261937185636 1.2261127599738322e-14 BR00116996 PLD1 final crispr F11 U2OS 144 1832 Polylobed +0.18237704918032788 1.350847493187362e-14 BR00116996 HRH4 final crispr H24 U2OS 144 976 Polylobed +0.13009638842396296 4.289212418345283e-14 BR00116999 MET final crispr E20 U2OS 144 1842 Polylobed +0.10778998382304167 6.114110290814654e-14 BR00116997 HRH4 final crispr A08 U2OS 144 2664 Polylobed +0.15611911696105502 6.35773023659569e-14 BR00116996 PARP3 final crispr F12 U2OS 144 1260 Polylobed +0.10933083595713214 7.736881251691879e-14 BR00116996 ALK final crispr I15 U2OS 144 2572 Polylobed +0.13146067415730336 8.060967461977786e-14 BR00116996 CHRM2 final crispr O22 U2OS 144 1780 Polylobed +0.1321893513101937 1.0172420696433054e-13 BR00116999 S1PR2 final crispr K02 U2OS 144 1736 Polylobed +0.1275342517208027 1.4801718061616142e-13 BR00116996 MMP2 final crispr E07 U2OS 144 1844 Polylobed +0.09283667621776505 1.6630302596928598e-13 BR00116999 PDE3A final crispr P18 U2OS 144 3490 Polylobed +0.12917819999974595 2.2825540195286725e-13 BR00116996 HIF1A final crispr M24 U2OS 144 1772 Polylobed +0.12372799536575162 2.5017642732704123e-13 BR00116999 JAK1 final crispr M21 U2OS 144 1932 Polylobed +0.11469534050179211 3.3422656764559955e-13 BR00116997 CDK4 final crispr P03 U2OS 144 2232 Polylobed +0.1609114862508557 4.418643850611598e-13 BR00116996 PRKCE final crispr I17 U2OS 144 1114 Polylobed +0.1251360174102285 5.916650326447601e-13 BR00116999 AGER final crispr K20 U2OS 144 1838 Polylobed +0.17675156564191918 6.373753882690561e-13 BR00116999 IL1B final crispr H18 U2OS 144 914 Polylobed +0.11952113455257306 1.649860883575663e-12 BR00116996 CASP3 final crispr E11 U2OS 144 1938 Polylobed +0.13404365157325454 1.6517885481113752e-12 BR00116998 CDC25A final crispr C14 U2OS 144 1534 Polylobed +0.1323529411764706 2.3522938929327713e-12 BR00116999 GUCY1B1 final crispr H21 U2OS 144 1564 Polylobed +0.1831465456093063 3.5083309581784276e-12 BR00116996 RPL3 final crispr H11 U2OS 144 798 Polylobed +0.13080288256344594 3.888968615758001e-12 BR00116996 RET final crispr I03 U2OS 144 1562 Polylobed +0.13656219199684605 4.542542889586667e-12 BR00116999 KCNN1 final crispr D01 U2OS 144 1424 Polylobed +0.13667896956541964 5.1404783942592e-12 BR00116999 GRIN2A final crispr A23 U2OS 144 1422 Polylobed +0.13517922182952408 7.587061604153754e-12 BR00116999 PDE4D final crispr P06 U2OS 144 1426 Polylobed +0.119531486731366 8.165544510419145e-12 BR00116996 OPRM1 final crispr C23 U2OS 144 1828 Polylobed +0.10767346482829057 8.908654229807957e-12 BR00116996 PDPK1 final crispr N18 U2OS 144 2238 Polylobed +0.12124515653569284 9.869632213198174e-12 BR00116996 HDAC3 final crispr G07 U2OS 144 1754 Polylobed +0.09701268498942918 1.0369693819783751e-11 BR00116999 CYP2A6 final crispr O04 U2OS 144 2752 Polylobed +0.09223678582846033 1.120022149968934e-11 BR00116998 RNASE1 final crispr K09 U2OS 144 3032 Polylobed +0.12159133208720746 1.2354768376164058e-11 BR00116998 BAX final crispr E06 U2OS 144 1732 Polylobed +0.13282919829311582 1.2567388416236825e-11 BR00116999 CLK1 final crispr N05 U2OS 144 1456 Polylobed +0.15272727272727274 1.3158823585148987e-11 BR00116999 GHSR final crispr B20 U2OS 144 1100 Polylobed +0.15747459263044342 1.3483193198558907e-11 BR00116997 BAX final crispr E06 U2OS 144 1026 Polylobed +0.1352892102335929 1.365058249971607e-11 BR00116997 FLT3 final crispr J20 U2OS 144 1392 Polylobed +0.11858838805416434 1.8086803979286353e-11 BR00116999 AKT1 final crispr J19 U2OS 144 1800 Polylobed +0.134983192786661 1.8467511707697607e-11 BR00116997 DYRK1B final crispr N16 U2OS 144 1384 Polylobed +0.10420240137221269 1.934471112727572e-11 BR00116996 P2RY12 final crispr O21 U2OS 144 2332 Polylobed +0.13421310093466762 2.1043529551145173e-11 BR00116996 CDK9 final crispr I20 U2OS 144 1396 Polylobed +0.183237415312887 2.510443637654235e-11 BR00116997 HTR2C final crispr L03 U2OS 144 740 Polylobed +0.09156520158882629 3.0499100591193333e-11 BR00116996 IGF1R final crispr M22 U2OS 144 2964 Polylobed +0.1361573373676248 4.247469620587913e-11 BR00116996 BTK final crispr P17 U2OS 144 1322 Polylobed +0.08259354031252142 4.394564896826639e-11 BR00116998 DHH final crispr K21 U2OS 144 3578 Polylobed +0.14375205491010767 4.5800471750702996e-11 BR00116999 CTSG final crispr G18 U2OS 144 1172 Polylobed +0.1202131621923617 5.756182881067497e-11 BR00116999 VEGFA final crispr H02 U2OS 144 1672 Polylobed +0.0895913931249308 6.329394044858472e-11 BR00116997 ADH1C final crispr D02 U2OS 144 2992 Polylobed +0.09242320562316536 6.681277531064801e-11 BR00116999 LPAR1 final crispr B16 U2OS 144 2804 Polylobed +0.14198950766747376 7.734095682890133e-11 BR00116999 PTGIR final crispr G10 U2OS 144 1180 Polylobed +0.12394316863699319 8.744725691173826e-11 BR00116996 DCK final crispr J08 U2OS 144 1538 Polylobed +0.13069172317727232 8.831223161216658e-11 BR00116997 S1PR2 final crispr K02 U2OS 144 1384 Polylobed +0.11013661202185793 9.458128923929147e-11 BR00116999 P3H1 final crispr N02 U2OS 144 1952 Polylobed +0.11388237364905472 9.972640250066521e-11 BR00116999 FPR1 final crispr I18 U2OS 144 1822 Polylobed +0.12452801750460614 1.0114158058816544e-10 BR00116996 PTGIS final crispr I16 U2OS 144 1518 Polylobed +0.09016521749473659 1.0799166676556075e-10 BR00116996 VEGFA final crispr C24 U2OS 144 2900 Polylobed +0.10199950639222075 1.13777553602127e-10 BR00116999 DNMT3A final crispr L04 U2OS 144 2250 Polylobed +0.08666902228134353 1.3721315449008958e-10 BR00116997 AKR1C1 final crispr B06 U2OS 144 3100 Polylobed +0.109997480777235 1.490135445400597e-10 BR00116999 EZH2 final crispr H09 U2OS 144 1910 Polylobed +0.15541540258246367 1.5945463119212032e-10 BR00116999 CDK9 final crispr M04 U2OS 144 956 Polylobed +0.0963198833564565 1.656841675161305e-10 BR00116999 ERBB2 final crispr H12 U2OS 144 2496 Polylobed +0.11704418654586031 1.6997766335811267e-10 BR00116999 CACNA2D3 final crispr O07 U2OS 144 1686 Polylobed +0.10781026025433647 1.7036100248709998e-10 BR00116996 PTGIR final crispr G08 U2OS 144 1988 Polylobed +0.12416555407209613 1.7722687210538074e-10 BR00116996 P2RY12 final crispr P19 U2OS 144 1498 Polylobed +0.1227154046997389 1.818173031909921e-10 BR00116996 S1PR1 final crispr P23 U2OS 144 1532 Polylobed +0.11739090285760821 1.8738329396950555e-10 BR00116999 PDPK1 final crispr E16 U2OS 144 1658 Polylobed +0.09353264926992726 1.875008597240838e-10 BR00116997 CA5A final crispr M01 U2OS 144 2628 Polylobed +0.12312435224058882 2.0650948885407805e-10 BR00116996 AGER final crispr K20 U2OS 144 1508 Polylobed +0.1437613019891501 2.2077986090785637e-10 BR00116999 HBB final crispr M08 U2OS 144 1106 Polylobed +0.13474025974025974 3.3647848009884654e-10 BR00116996 AKR1B1 final crispr H17 U2OS 144 1228 Polylobed +0.11645640145689044 3.455965724594878e-10 BR00116996 GRIN2A final crispr A23 U2OS 144 1642 Polylobed +0.09284004457139082 3.701018225708248e-10 BR00116999 CYP3A4 final crispr D04 U2OS 144 2580 Polylobed 0.17591125198098256 1.8158660828366578e-17 BR00116996 ICAM1 final crispr I12 U2OS 144 1262 Prometaphase 0.12794102284156342 2.9059755788525676e-16 BR00116996 FFAR4 final crispr G11 U2OS 144 2210 Prometaphase 0.14490598533819518 6.658107190628588e-14 BR00116996 PIK3CG final crispr I08 U2OS 144 1466 Prometaphase @@ -1189,6 +11809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.11454317252920541 1.603875228878104e-11 BR00116999 JAK1 final crispr M21 U2OS 144 1932 Prometaphase 0.09842348082503011 2.6829578096162074e-11 BR00116996 ALK final crispr I15 U2OS 144 2572 Prometaphase 0.08598600013043357 8.825309534592238e-11 BR00116998 ALDH2 final crispr A10 U2OS 144 3212 Prometaphase +0.09287964361977932 1.598138663069693e-10 BR00116996 HDAC6 final crispr K12 U2OS 144 2680 Prometaphase +0.15106594295988898 6.976319346425714e-10 BR00116996 CDK7 final crispr I14 U2OS 144 942 Prometaphase +0.0969200817056045 1.298826805181346e-09 BR00116996 PDPK1 final crispr N18 U2OS 144 2238 Prometaphase +0.17951368190296713 1.5439457293766045e-09 BR00116998 TGFBR1 final crispr B08 U2OS 144 646 Prometaphase +0.1196218974419876 2.233725919382156e-09 BR00116999 PDE4D final crispr P06 U2OS 144 1426 Prometaphase +0.11588485835977475 2.387280037765979e-09 BR00116996 PTGIS final crispr I16 U2OS 144 1518 Prometaphase +0.13157894736842105 2.640968118902178e-09 BR00116996 PPAT final crispr G13 U2OS 144 1178 Prometaphase +0.11061279957769551 2.784523299383097e-09 BR00116999 PDPK1 final crispr E16 U2OS 144 1658 Prometaphase +0.117213268469184 2.8122669949151505e-09 BR00116999 PIK3CG final crispr I08 U2OS 144 1474 Prometaphase +0.13829610628852343 2.9119637160804055e-09 BR00116997 ALK final crispr I15 U2OS 144 1058 Prometaphase +0.1032258064516129 4.7925611657904786e-09 BR00116996 MME final crispr G17 U2OS 144 1860 Prometaphase +0.224526253590029 5.309049046189695e-09 BR00116999 RPL3 final crispr K04 U2OS 144 382 Prometaphase +0.09929078014184398 6.877599907302644e-09 BR00116996 BRAF final crispr J10 U2OS 144 1974 Prometaphase +0.1254071661237785 7.851388521377327e-09 BR00116997 PDPK1 final crispr E16 U2OS 144 1228 Prometaphase +0.09849246231155778 8.048055125589009e-09 BR00116999 HPGDS final crispr P14 U2OS 144 1990 Prometaphase +0.11914205715858608 9.792865809817978e-09 BR00116996 RNASE1 final crispr I13 U2OS 144 1332 Prometaphase +0.11112989030269374 1.6893545869019897e-08 BR00116997 PTGIS final crispr I16 U2OS 144 1494 Prometaphase +0.07976519337016574 1.9575045189901944e-08 BR00116999 FFAR2 final crispr A06 U2OS 144 2896 Prometaphase +0.12106502086918679 2.5106037127887958e-08 BR00116996 ERBB2 final crispr I11 U2OS 144 1230 Prometaphase +0.12133550488599348 2.711840335354732e-08 BR00116998 SLCO2B1 final crispr A21 U2OS 144 1228 Prometaphase +0.10198883806944835 3.603910157147195e-08 BR00116999 CYP1A2 final crispr M15 U2OS 144 1704 Prometaphase +0.09738846572361262 5.250876333566799e-08 BR00116999 AGER final crispr K20 U2OS 144 1838 Prometaphase +0.09400262658689625 5.252002977833439e-08 BR00116999 ADA final crispr O06 U2OS 144 1960 Prometaphase +0.1167192429022082 6.090916911933814e-08 BR00116997 S1PR1 final crispr P23 U2OS 144 1268 Prometaphase +0.12324503054647844 7.455053973376407e-08 BR00116996 PRKCE final crispr I17 U2OS 144 1114 Prometaphase +0.09810706262467264 9.984545918373333e-08 BR00116998 OPRL1 final crispr A04 U2OS 144 1738 Prometaphase +0.11893165041651027 1.1310230189758261e-07 BR00116999 CTSG final crispr G18 U2OS 144 1172 Prometaphase +0.10460589878265146 1.228729505545381e-07 BR00116996 AGER final crispr K20 U2OS 144 1508 Prometaphase +0.1026273022751896 1.2314573954062044e-07 BR00116996 RET final crispr I03 U2OS 144 1562 Prometaphase +0.08908045977011494 1.251417550928544e-07 BR00116999 PTGIS final crispr I16 U2OS 144 2088 Prometaphase +0.08924696180555555 1.4613809384853045e-07 BR00116998 ADH1C final crispr P04 U2OS 144 2052 Prometaphase +0.15457304330443947 2.0144388059175869e-07 BR00116997 CDK4 final crispr B15 U2OS 144 664 Prometaphase +0.09324347999444206 2.27429711936879e-07 BR00116996 FLT3 final crispr G16 U2OS 144 1820 Prometaphase +0.08813833192898984 2.3099339731617005e-07 BR00116996 MME final crispr H08 U2OS 144 2038 Prometaphase +0.09259681039067587 2.5864421543238907e-07 BR00116996 PLD1 final crispr F11 U2OS 144 1832 Prometaphase +0.1343920876631157 3.0623659480507194e-07 BR00116997 CDK7 final crispr E12 U2OS 144 858 Prometaphase +0.08333333333333333 3.65734257090063e-07 BR00116997 CDK4 final crispr P03 U2OS 144 2232 Prometaphase +0.08277486549188015 3.823384884473997e-07 BR00116999 DNMT3A final crispr L04 U2OS 144 2250 Prometaphase +0.09040760681166982 3.9529492748199856e-07 BR00116996 FPR1 final crispr I18 U2OS 144 1878 Prometaphase +0.10363455727118434 4.0139610512529077e-07 BR00116997 ICAM1 final crispr I12 U2OS 144 1428 Prometaphase +0.08027021201790434 4.23802664675836e-07 BR00116999 CA14 final crispr G15 U2OS 144 2364 Prometaphase +0.07666169833543532 4.408719566716038e-07 BR00116998 CATSPER4 final crispr A02 U2OS 144 2590 Prometaphase +0.08793158175892067 4.4625204466709273e-07 BR00116996 ALK final crispr G06 U2OS 144 1970 Prometaphase +0.09565772113725661 4.5921118907661817e-07 BR00116999 ADH1C final crispr P04 U2OS 144 1660 Prometaphase +0.121328125 5.208153137399927e-07 BR00116999 FLT3 final crispr G16 U2OS 144 1024 Prometaphase +0.09913375752126703 5.934274826745354e-07 BR00116996 TNNC1 final crispr D09 U2OS 144 1520 Prometaphase +0.11062678247342494 6.104256169824262e-07 BR00116998 BTK final crispr D24 U2OS 144 1218 Prometaphase +0.08315720349302438 6.932807731275484e-07 BR00116999 NAMPT final crispr I09 U2OS 144 2144 Prometaphase +0.08735868448098665 6.994674083108977e-07 BR00116999 PLA2G1B final crispr J11 U2OS 144 1946 Prometaphase +0.1009239037846464 7.574475985728919e-07 BR00116996 ADRA2B final crispr J14 U2OS 144 1442 Prometaphase +0.09760157032040014 7.592443327440958e-07 BR00116998 CDC25A final crispr C14 U2OS 144 1534 Prometaphase +0.13526268501442285 7.78186495918323e-07 BR00116996 RPL3 final crispr H11 U2OS 144 798 Prometaphase +0.10314275694248715 8.335971826841719e-07 BR00116999 PPAT final crispr E13 U2OS 144 1364 Prometaphase +0.10440497871082267 9.487559005995889e-07 BR00116996 PDPK1 final crispr E16 U2OS 144 1318 Prometaphase +0.08917005796029104 1.1051710881607183e-06 BR00116998 AKR1C1 final crispr B13 U2OS 144 1802 Prometaphase +0.14122918047937638 1.190785549390622e-06 BR00116997 CDK2 final crispr L19 U2OS 144 706 Prometaphase +0.06595744680851064 1.2064422306665051e-06 BR00116998 HIF1A final crispr A01 U2OS 144 3290 Prometaphase +0.11301989150090416 1.4295593890784389e-06 BR00116999 HBB final crispr M08 U2OS 144 1106 Prometaphase +0.0883528102392877 1.4343298851890578e-06 BR00116999 AKT1 final crispr J19 U2OS 144 1800 Prometaphase +0.06619018023617154 1.4948589131750637e-06 BR00116999 CATSPER4 final crispr A02 U2OS 144 3218 Prometaphase +0.07622203811101906 1.6049679225510085e-06 BR00116999 ABL1 final crispr C01 U2OS 144 2414 Prometaphase +0.07863675499706194 1.639138194711096e-06 BR00116999 ALK final crispr I15 U2OS 144 2256 Prometaphase +0.09754412092390921 1.7651333618495694e-06 BR00116996 PORCN final crispr L13 U2OS 144 1458 Prometaphase +0.08548637105126002 1.9297443293072846e-06 BR00116997 CHRM2 final crispr B07 U2OS 144 1884 Prometaphase +0.08934622230800575 1.953254022574399e-06 BR00116997 ADH1C final crispr P04 U2OS 144 1728 Prometaphase +0.16210015147465026 1.9559807319949013e-06 BR00116998 HPGDS final crispr B19 U2OS 144 522 Prometaphase +0.1480891719745223 2.007039045893236e-06 BR00116996 TUBB4B final crispr J13 U2OS 144 628 Prometaphase +0.0810744821931237 2.0621488883871796e-06 BR00116999 CACNB4 final crispr B01 U2OS 144 2090 Prometaphase +0.20426829268292682 2.1110169294887305e-06 BR00116998 CHRM3 final crispr B17 U2OS 144 328 Prometaphase +0.10363924050632911 2.4915513076897293e-06 BR00116999 PORCN final crispr L13 U2OS 144 1264 Prometaphase +0.21929546175817202 2.50052452508118e-06 BR00116997 RPL23A final crispr G14 U2OS 144 276 Prometaphase +0.08383988057997739 2.6845813485282104e-06 BR00116997 ABL1 final crispr C01 U2OS 144 1908 Prometaphase +0.08762394068516517 3.6284986975167074e-06 BR00116998 OPRL1 final crispr A11 U2OS 144 1716 Prometaphase +0.0709176597795172 3.6913881563862696e-06 BR00116996 DNMT3A final crispr L04 U2OS 144 2608 Prometaphase +0.0869319553902949 3.72497484678946e-06 BR00116998 PDE4D final crispr P06 U2OS 144 1732 Prometaphase +0.08367047430852877 3.8130360854455653e-06 BR00116997 PDE4D final crispr P06 U2OS 144 1860 Prometaphase +0.0928665718208972 3.98876605342791e-06 BR00116999 CLK1 final crispr M11 U2OS 144 1504 Prometaphase +0.08010621141378998 4.080504273578484e-06 BR00116996 BTK final crispr D24 U2OS 144 2028 Prometaphase +0.12631078378773838 4.19756317462235e-06 BR00116997 CDK7 final crispr I14 U2OS 144 808 Prometaphase +0.0785012603038354 4.394715537908402e-06 BR00116998 USP1 final crispr K18 U2OS 144 2100 Prometaphase +0.05811621994206446 4.4269342972000295e-06 BR00116996 TNF final crispr I10 U2OS 144 3836 Prometaphase +0.0827369811411904 6.245022070085476e-06 BR00116999 MET final crispr E20 U2OS 144 1842 Prometaphase +0.10130718954248366 6.890519254645329e-06 BR00116996 MAPK8 final crispr D13 U2OS 144 1224 Prometaphase +0.08747697553698376 7.631359414252783e-06 BR00116999 ITGB2 final crispr D23 U2OS 144 1622 Prometaphase +0.07663197729422895 8.044935099053087e-06 BR00116998 VEGFA final crispr C24 U2OS 144 2114 Prometaphase +0.09817189253249618 9.030715518789541e-06 BR00116996 PARP3 final crispr F12 U2OS 144 1260 Prometaphase +0.09236111111111112 9.128375155433621e-06 BR00116998 FOXM1 final crispr A19 U2OS 144 1440 Prometaphase +0.09050556875355668 9.207772723507172e-06 BR00116996 CDK2 final crispr F08 U2OS 144 1490 Prometaphase +0.11240568575404712 1.0330019891742202e-05 BR00116999 TUBB final crispr J17 U2OS 144 948 Prometaphase +0.11270639869403484 1.083212427040365e-05 BR00116999 CDK7 final crispr I14 U2OS 144 946 Prometaphase 0.2540962031979996 3.008296195987506e-57 BR00116996 OPRM1 final crispr P22 U2OS 144 2002 SmallIrregular 0.19682675814751285 6.5552124276027474e-40 BR00116996 ABL1 final crispr P20 U2OS 144 2332 SmallIrregular 0.20786516853932585 4.61519369186257e-34 BR00116996 CHRM2 final crispr O22 U2OS 144 1780 SmallIrregular @@ -1199,6 +11909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.18361640790524816 1.8312756835814747e-27 BR00116996 OPRM1 final crispr C23 U2OS 144 1828 SmallIrregular 0.19893190921228304 2.4633194819049937e-26 BR00116996 P2RY12 final crispr P19 U2OS 144 1498 SmallIrregular 0.2546106944369503 4.28517630193638e-25 BR00116996 ADA final crispr O24 U2OS 144 862 SmallIrregular +0.1682456177000353 2.25551013421399e-23 BR00116996 HTR3A final crispr O20 U2OS 144 1856 SmallIrregular +0.25185409559034533 1.397104557407266e-22 BR00116996 FFAR2 final crispr A24 U2OS 144 794 SmallIrregular +0.17510172450071274 1.8609079371123427e-22 BR00116996 GRIN2A final crispr A23 U2OS 144 1642 SmallIrregular +0.19213313161875945 9.6044661273199e-22 BR00116996 BTK final crispr P17 U2OS 144 1322 SmallIrregular +0.15348064504526573 2.8154932329052953e-21 BR00116996 BTK final crispr D24 U2OS 144 2028 SmallIrregular +0.17806267806267806 7.441053673461556e-20 BR00116996 CACNA2D3 final crispr N24 U2OS 144 1404 SmallIrregular +0.18574081313526192 7.732285041042071e-20 BR00116996 GPR119 final crispr P21 U2OS 144 1280 SmallIrregular +0.17303469347526118 4.2987447716770665e-19 BR00116999 KCNN1 final crispr D01 U2OS 144 1424 SmallIrregular +0.16209476309226933 8.367975442612347e-19 BR00116996 SLCO2B1 final crispr A21 U2OS 144 1604 SmallIrregular +0.18494857653433705 1.7118739775896475e-17 BR00116996 KCNH7 final crispr P16 U2OS 144 1134 SmallIrregular +0.16820987654320987 2.0222080508212726e-16 BR00116997 CSK final crispr B11 U2OS 144 1296 SmallIrregular +0.1350035223625451 3.2445154747342766e-16 BR00116996 SLCO2B1 final crispr I24 U2OS 144 1982 SmallIrregular +0.14180442092399623 4.911527380161216e-16 BR00116996 HIF1A final crispr M24 U2OS 144 1772 SmallIrregular +0.17544592212114954 5.200781200514514e-16 BR00116998 BRD4 final crispr M19 U2OS 144 1158 SmallIrregular +0.12708719851576994 1.382405243661859e-15 BR00116997 DYRK1B final crispr K14 U2OS 144 2156 SmallIrregular +0.1223072983870066 1.5788741916867978e-15 BR00116996 HCK final crispr M23 U2OS 144 2316 SmallIrregular +0.12178387650085763 1.7625600805571967e-15 BR00116996 P2RY12 final crispr O21 U2OS 144 2332 SmallIrregular +0.2014953895458625 2.138659478621793e-15 BR00116998 MAPK8 final crispr D13 U2OS 144 842 SmallIrregular +0.16378887508434192 2.242237430030058e-15 BR00116996 KDR final crispr O18 U2OS 144 1268 SmallIrregular +0.17417296032336985 3.629344612523493e-15 BR00116998 PPAT final crispr E13 U2OS 144 1106 SmallIrregular +0.12771203155818542 7.942429436183235e-15 BR00116998 KCTD16 final crispr D08 U2OS 144 2028 SmallIrregular +0.12107208872458411 3.1201437104367505e-14 BR00116996 SCNN1G final crispr G24 U2OS 144 2164 SmallIrregular +0.1704480793453655 4.6850507527929776e-14 BR00116996 CHRM3 final crispr B21 U2OS 144 1066 SmallIrregular +0.13501787255022804 5.030164220837433e-14 BR00116999 RGS4 final crispr N11 U2OS 144 1708 SmallIrregular +0.1264131551901336 5.791531314561626e-14 BR00116996 ELANE final crispr N19 U2OS 144 1946 SmallIrregular +0.12205262506244872 1.0056488205861256e-13 BR00116996 FPR1 final crispr N22 U2OS 144 2038 SmallIrregular +0.1497350567028178 6.229466711805545e-13 BR00116996 SIRT2 final crispr P01 U2OS 144 1272 SmallIrregular +0.14905362776025236 1.0607882587375366e-12 BR00116997 S1PR1 final crispr P23 U2OS 144 1268 SmallIrregular +0.22136220016078673 1.339984110964089e-12 BR00116999 SLC7A11 final crispr P05 U2OS 144 566 SmallIrregular +0.09163672743772268 1.9016418826317875e-12 BR00116996 CYP1A2 final crispr K22 U2OS 144 3280 SmallIrregular +0.10867756934364459 1.9666580782755412e-12 BR00116996 HPGDS final crispr P14 U2OS 144 2330 SmallIrregular +0.16330645161290322 5.830895011382037e-12 BR00116996 FOXM1 final crispr A19 U2OS 144 992 SmallIrregular +0.16063952306754284 6.5635589616659315e-12 BR00116998 GJB4 final crispr H01 U2OS 144 1018 SmallIrregular +0.16846652267818574 6.9035504749745095e-12 BR00116998 CYP3A4 final crispr D04 U2OS 144 926 SmallIrregular +0.074181777881216 8.503309509683932e-12 BR00116998 TNF final crispr I10 U2OS 144 4750 SmallIrregular +0.16188524590163936 1.4106928107775395e-11 BR00116996 HRH4 final crispr H24 U2OS 144 976 SmallIrregular +0.13291139240506328 2.3065477729643666e-11 BR00116998 CA5A final crispr M01 U2OS 144 1422 SmallIrregular +0.09659878118652013 3.963441014733542e-11 BR00116997 CA5A final crispr M01 U2OS 144 2628 SmallIrregular +0.09705390315033233 5.1012905491826344e-11 BR00116999 CYP3A4 final crispr D04 U2OS 144 2580 SmallIrregular +0.09376215644820296 5.664232499991955e-11 BR00116999 CYP2A6 final crispr O04 U2OS 144 2752 SmallIrregular +0.13197207416860596 5.850222996857362e-11 BR00116997 DYRK1B final crispr N16 U2OS 144 1384 SmallIrregular +0.09501819625786567 6.322998057025834e-11 BR00116997 HRH4 final crispr A08 U2OS 144 2664 SmallIrregular +0.10815320017358464 9.573738497770823e-11 BR00116996 CACNG1 final crispr N23 U2OS 144 2022 SmallIrregular +0.1662437116959654 1.1008621274529877e-10 BR00116998 AURKB final crispr C13 U2OS 144 846 SmallIrregular +0.17948630019546655 1.1062319731008622e-10 BR00116998 FFAR2 final crispr A24 U2OS 144 726 SmallIrregular +0.18699537861214507 1.1803357518595385e-10 BR00116996 MAPK14 final crispr A20 U2OS 144 666 SmallIrregular +0.11176470588235295 1.373803682909009e-10 BR00116999 S1PR1 final crispr P23 U2OS 144 1870 SmallIrregular +0.13153961136023917 1.6644965563748638e-10 BR00116996 SIRT2 final crispr O19 U2OS 144 1338 SmallIrregular +0.11934673366834171 2.707836507715907e-10 BR00116996 HSD11B1 final crispr O23 U2OS 144 1592 SmallIrregular +0.08591681571591692 5.357035130524787e-10 BR00116996 IGF1R final crispr M22 U2OS 144 2964 SmallIrregular +0.2367289167388108 7.948360125971496e-10 BR00116999 RPL3 final crispr K04 U2OS 144 382 SmallIrregular +0.1497176653196671 1.037272096762195e-09 BR00116998 BRD4 final crispr J16 U2OS 144 948 SmallIrregular +0.10033142388588208 1.2035785520511342e-09 BR00116999 CACNB4 final crispr B01 U2OS 144 2090 SmallIrregular +0.07934131736526946 1.4506416559489922e-09 BR00116999 ANXA1 final crispr G01 U2OS 144 3340 SmallIrregular +0.11543367346938775 1.6208879331041303e-09 BR00116998 IMPDH1 final crispr G05 U2OS 144 1568 SmallIrregular +0.13015989232247108 2.2233747141391403e-09 BR00116997 AKR1C1 final crispr B13 U2OS 144 1204 SmallIrregular +0.12084532348278033 2.225917052110483e-09 BR00116996 CDK9 final crispr I20 U2OS 144 1396 SmallIrregular +0.12448650640140002 2.2722114175153203e-09 BR00116998 BTK final crispr P17 U2OS 144 1316 SmallIrregular +0.1047958881736063 2.4320827101476687e-09 BR00116996 BRD4 final crispr M19 U2OS 144 1852 SmallIrregular +0.146947179823529 2.771895166515397e-09 BR00116999 CDK4 final crispr B15 U2OS 144 934 SmallIrregular +0.21409527008586485 3.1831671157284987e-09 BR00116996 KCNN4 final crispr A22 U2OS 144 436 SmallIrregular +0.0958568173120412 4.703885446008637e-09 BR00116999 NAMPT final crispr I09 U2OS 144 2144 SmallIrregular +0.09502499162706303 5.367725793943507e-09 BR00116998 ATM final crispr F14 U2OS 144 2170 SmallIrregular +0.09502162192159759 5.432494727408412e-09 BR00116998 BRAF final crispr J10 U2OS 144 2164 SmallIrregular +0.12874886573150926 5.897278444146962e-09 BR00116996 GPR119 final crispr G23 U2OS 144 1176 SmallIrregular +0.1023976923388799 7.79753275203833e-09 BR00116996 CA14 final crispr C19 U2OS 144 1832 SmallIrregular +0.09962938459858563 8.325748007232002e-09 BR00116997 ADA final crispr O06 U2OS 144 1934 SmallIrregular +0.08013397561611636 8.416696029079979e-09 BR00116997 ADH1C final crispr D02 U2OS 144 2992 SmallIrregular +0.12121608120196779 9.564852156805437e-09 BR00116999 FGF1 final crispr J12 U2OS 144 1298 SmallIrregular +0.15625456089373616 1.0341665674756928e-08 BR00116996 CCND1 final crispr B23 U2OS 144 776 SmallIrregular +0.11458333333333333 1.1883842620481517e-08 BR00116998 FOXM1 final crispr A19 U2OS 144 1440 SmallIrregular +0.07765712861426065 1.3307953566052848e-08 BR00116998 RGS4 final crispr E08 U2OS 144 3110 SmallIrregular +0.13028641072516758 1.3313871181624933e-08 BR00116998 PDPK1 final crispr N18 U2OS 144 1094 SmallIrregular +0.10278337593077337 1.3759770741545762e-08 BR00116998 PPAT final crispr G13 U2OS 144 1762 SmallIrregular +0.09372887189902734 1.9249216148275462e-08 BR00116996 PDE4D final crispr J24 U2OS 144 2094 SmallIrregular +0.1140591621932162 2.2324830681673238e-08 BR00116998 KCNN1 final crispr D01 U2OS 144 1396 SmallIrregular +0.11417073160589011 2.35502445900495e-08 BR00116998 LYN final crispr F22 U2OS 144 1386 SmallIrregular +0.0750625770567355 2.563241224213333e-08 BR00116998 ALDH2 final crispr A10 U2OS 144 3212 SmallIrregular +0.08765927113962399 3.2057722931729365e-08 BR00116999 UGT1A9 final crispr J01 U2OS 144 2320 SmallIrregular +0.09580904267777751 3.565086433356979e-08 BR00116998 HDAC6 final crispr K12 U2OS 144 1928 SmallIrregular +0.11521197572243863 3.653970770206417e-08 BR00116999 BTK final crispr D24 U2OS 144 1330 SmallIrregular +0.13578380210702848 4.465331854742304e-08 BR00116999 CDK7 final crispr I14 U2OS 144 946 SmallIrregular +0.09321676848535917 4.493066360600262e-08 BR00116999 HIF1A final crispr M24 U2OS 144 2020 SmallIrregular +0.1767857142857143 4.6440416667497734e-08 BR00116998 S1PR1 final crispr A18 U2OS 144 560 SmallIrregular +0.12006578947368421 4.7073214997537424e-08 BR00116996 S1PR1 final crispr A18 U2OS 144 1216 SmallIrregular +0.12252626380195354 5.352254805186595e-08 BR00116998 ALDH2 final crispr O09 U2OS 144 1154 SmallIrregular +0.07531004162924622 6.371826887886072e-08 BR00116998 RNASE1 final crispr K09 U2OS 144 3032 SmallIrregular +0.18925366756872242 6.566652863615513e-08 BR00116997 AURKB final crispr C13 U2OS 144 476 SmallIrregular +0.09515684981969057 6.75481567064972e-08 BR00116998 GUCY1B1 final crispr N08 U2OS 144 1886 SmallIrregular +0.11963510236309288 6.759302411978536e-08 BR00116996 ANXA1 final crispr F24 U2OS 144 1190 SmallIrregular 0.12715355805243445 5.094166447988909e-38 BR00117021 HPGDS final orf O24 A549 48 5340 ADCCM 0.10197608294916453 2.8269956663248193e-20 BR00117020 CCR1 final orf F24 A549 48 4380 ADCCM 0.10989082309175767 3.882131320728396e-20 BR00117021 UGT1A9 final orf E24 A549 48 3745 ADCCM @@ -1209,6 +12009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.09096943808429188 2.2713087825149883e-17 BR00117020 MET final orf C08 A549 48 4700 ADCCM 0.08878742786367197 1.4187047533286525e-16 BR00117020 GHSR final orf C24 A549 48 4705 ADCCM 0.086875 3.545624285405178e-16 BR00117020 AKR1C1 final orf A24 A549 48 4800 ADCCM +0.08960136673316946 2.5014680637420966e-15 BR00117020 S100B final orf M20 A549 48 4255 ADCCM +0.08943012164265848 9.269568569859813e-15 BR00117021 OPRL1 final orf A23 A549 48 4110 ADCCM +0.08363941404435571 1.3218652987118473e-14 BR00117021 KRAS final orf F08 A549 48 4650 ADCCM +0.07996051332675222 1.6718655007967132e-14 BR00117020 UGT1A9 final orf O09 A549 48 5065 ADCCM +0.08438538205980066 2.1039460072664026e-14 BR00117021 S100B final orf M20 A549 48 4515 ADCCM +0.09272917363849718 2.632540387203979e-14 BR00117021 CACNB4 final orf A18 A549 48 3705 ADCCM +0.08758846713137187 3.4877930262162055e-14 BR00117021 ASIC1 final orf L21 A549 48 4105 ADCCM +0.07776708373435996 4.4049321991379386e-14 BR00117021 FPR1 final orf L04 A549 48 5195 ADCCM +0.07593984962406015 9.234763514255371e-14 BR00117020 ABL1 final orf C01 A549 48 5320 ADCCM +0.07978835978835978 1.678225893049359e-13 BR00117021 KCNK1 final orf C22 A549 48 4725 ADCCM +0.0805708013172338 2.7967265242269425e-13 BR00117021 PRKCE final orf L14 A549 48 4555 ADCCM +0.08232558139534883 4.279722983605775e-13 BR00117021 CCR1 final orf F24 A549 48 4300 ADCCM +0.07616710484583768 4.741801894034549e-13 BR00117020 HSP90AA1 final orf C14 A549 48 4985 ADCCM +0.07584375121894138 7.07233727943807e-13 BR00117020 RET final orf E03 A549 48 4960 ADCCM +0.07573102466831548 7.497488665494203e-13 BR00117021 P3H1 final orf P24 A549 48 4970 ADCCM +0.07872807017543859 1.035236978361833e-12 BR00117021 CYP2A6 final orf A20 A549 48 4560 ADCCM +0.08093023255813954 1.142144807904132e-12 BR00117021 CATSPER4 final orf D24 A549 48 4300 ADCCM +0.0793763061299766 3.1459510828736044e-12 BR00117021 TBXAS1 final orf J24 A549 48 4290 ADCCM +0.07230320699708455 4.08169255987282e-12 BR00117020 PRKCE final orf L14 A549 48 5145 ADCCM +0.06565350845251268 4.991558727760588e-12 BR00117020 DHH final orf G05 A549 48 6190 ADCCM +0.07401504179787147 6.711126883103e-12 BR00117021 FGF1 final orf F22 A549 48 4815 ADCCM +0.0733191162947791 9.220933353897745e-12 BR00117020 AKT1 final orf J16 A549 48 4845 ADCCM +0.0810540577087104 1.1708011491319508e-11 BR00117020 CDK4 final orf B21 A549 48 3920 ADCCM +0.0714675740592474 1.484307528490981e-11 BR00117021 LYN final orf M05 A549 48 5000 ADCCM +0.08432001131448372 1.7223295824238844e-11 BR00117021 GHSR final orf C24 A549 48 3565 ADCCM +0.07394594594594595 2.0374789799052334e-11 BR00117020 UGT1A9 final orf E24 A549 48 4625 ADCCM +0.0652820379427245 2.0935171002618103e-11 BR00117020 TUBB4B final orf E07 A549 48 5910 ADCCM +0.06838964292577383 3.149554822270795e-11 BR00117021 FLT3 final orf K13 A549 48 5300 ADCCM +0.0718179399636412 4.14910200012664e-11 BR00117021 GPR119 final orf N23 A549 48 4750 ADCCM +0.07350633158949788 4.462252085779811e-11 BR00117021 MAPK8 final orf I14 A549 48 4520 ADCCM +0.0688963532289922 5.115126048463127e-11 BR00117020 VEGFA final orf B09 A549 48 5130 ADCCM +0.07720588235294118 5.368243526201239e-11 BR00117021 FPR1 final orf D21 A549 48 4080 ADCCM +0.06648451730418943 5.691877805858216e-11 BR00117020 ICAM1 final orf I15 A549 48 5490 ADCCM +0.06944051131424357 8.498093376004642e-11 BR00117020 LYN final orf C20 A549 48 4930 ADCCM +0.06841046277665996 1.558322041241612e-10 BR00117020 FFAR2 final orf P06 A549 48 4970 ADCCM +0.07010357871826675 1.7250935185758278e-10 BR00117021 ERBB2 final orf I20 A549 48 4705 ADCCM +0.06579194001874414 1.8432072838262875e-10 BR00117021 PLK1 final orf L11 A549 48 5335 ADCCM +0.06707844238976964 3.5057627464755204e-10 BR00117020 VEGFA final orf P18 A549 48 4985 ADCCM +0.060290194797500904 4.063522133015701e-10 BR00117020 PTGIR final orf C07 A549 48 6120 ADCCM +0.0717140184937773 4.4179774508038577e-10 BR00117021 SLC7A11 final orf G24 A549 48 4315 ADCCM +0.06624905570346962 6.464766105243995e-10 BR00117021 GUCY1B1 final orf F05 A549 48 4955 ADCCM +0.07217832278027676 6.474920203573586e-10 BR00117021 GJB4 final orf H23 A549 48 4180 ADCCM +0.06328413284132842 7.389314660467017e-10 BR00117020 FGF1 final orf F22 A549 48 5420 ADCCM +0.06351327412570032 8.444159086215515e-10 BR00117021 FFAR4 final orf I16 A549 48 5325 ADCCM +0.06587245393447196 1.255668141522766e-09 BR00117020 GHSR final orf A17 A549 48 4865 ADCCM +0.06624627728562486 1.9788350430270335e-09 BR00117021 CDK4 final orf P20 A549 48 4710 ADCCM +0.068603162462797 1.990225767247082e-09 BR00117021 PRKCB final orf K19 A549 48 4390 ADCCM +0.06968754488008043 2.2792917379468833e-09 BR00117021 VEGFA final orf B09 A549 48 4220 ADCCM +0.06709284701510781 2.665406633832603e-09 BR00117021 GUCY1B1 final orf J08 A549 48 4520 ADCCM +0.06546020359821991 4.3596834139370245e-09 BR00117021 MMP2 final orf F06 A549 48 4630 ADCCM +0.06593382425799404 4.744255168405148e-09 BR00117021 CA5A final orf B23 A549 48 4550 ADCCM +0.06265060240963856 6.4146466740701995e-09 BR00117020 CYP1A2 final orf F21 A549 48 4980 ADCCM +0.06664999344662206 8.53455392772311e-09 BR00117020 PTK2B final orf N19 A549 48 4325 ADCCM +0.06389922350933683 8.581957264175024e-09 BR00117020 CASP3 final orf J10 A549 48 4705 ADCCM +0.06814363480202183 1.0551980635875718e-08 BR00117020 P2RY12 final orf B24 A549 48 4085 ADCCM +0.06316136947833001 1.1897084488853992e-08 BR00117020 HSP90AB1 final orf B16 A549 48 4740 ADCCM +0.06731798213017796 1.25812179138587e-08 BR00117021 MME final orf K20 A549 48 4145 ADCCM +0.058931860036832415 1.27946404937335e-08 BR00117020 SIRT2 final orf G02 A549 48 5430 ADCCM +0.06071502137334796 1.5415884684991375e-08 BR00117021 PDE3A final orf O22 A549 48 5050 ADCCM +0.0652881318237119 1.5789524637295223e-08 BR00117021 PTK2B final orf J18 A549 48 4355 ADCCM +0.05701503317381522 1.8024140497909427e-08 BR00117021 NTRK1 final orf P02 A549 48 5690 ADCCM +0.0604221309787012 1.8518985244012537e-08 BR00117021 MAPK8 final orf I13 A549 48 5050 ADCCM +0.06322097965564512 2.0254275787869303e-08 BR00117021 PRKCE final orf J19 A549 48 4585 ADCCM +0.06055341079359234 2.9379945367920905e-08 BR00117020 KCNN4 final orf A06 A549 48 4910 ADCCM +0.05945929427892623 3.0245172029685586e-08 BR00117021 TGFBR1 final orf O14 A549 48 5085 ADCCM +0.05824751588627323 3.091894598953416e-08 BR00117021 CACNA2D3 final orf P19 A549 48 5280 ADCCM +0.06201716738197425 3.2585635509437045e-08 BR00117021 PIK3CG final orf G18 A549 48 4660 ADCCM +0.06086901864077102 3.409645776143826e-08 BR00117021 CSF1R final orf J07 A549 48 4820 ADCCM +0.06410849984988945 4.261534689518165e-08 BR00117021 PTK2B final orf N19 A549 48 4285 ADCCM +0.06021519078748954 4.262059755042346e-08 BR00117021 CYP1A2 final orf F21 A549 48 4850 ADCCM +0.06472344927706418 4.872658851702503e-08 BR00117020 DYRK1B final orf M12 A549 48 4170 ADCCM +0.056460125475918485 5.2712599017739164e-08 BR00117020 SCNN1G final orf A04 A549 48 5450 ADCCM +0.056699024257976016 5.5370803516032397e-08 BR00117020 CCND1 final orf B11 A549 48 5395 ADCCM +0.05903614457831325 5.7479933937819584e-08 BR00117020 TGFBR1 final orf I23 A549 48 4980 ADCCM +0.06026635889704144 7.139665886269565e-08 BR00117020 SLC7A11 final orf G24 A549 48 4705 ADCCM +0.05929196748251913 8.21444177556765e-08 BR00117021 GABRB2 final orf C06 A549 48 4830 ADCCM +0.07000794736101862 8.941992164654723e-08 BR00117021 AKR1C1 final orf A24 A549 48 3435 ADCCM +0.05706986811637974 9.631148111514707e-08 BR00117020 KCNH7 final orf O07 A549 48 5160 ADCCM +0.055907352910337695 1.0236053667074048e-07 BR00117020 SIRT2 final orf A07 A549 48 5350 ADCCM +0.062370742689599204 1.0856314201886004e-07 BR00117021 KCNH7 final orf A22 A549 48 4280 ADCCM +0.06057984833760308 1.1343665816438031e-07 BR00117021 PARP3 final orf H21 A549 48 4525 ADCCM +0.0602425860019416 1.3152417676917972e-07 BR00117020 KRAS final orf F08 A549 48 4545 ADCCM +0.06237025856666166 1.7356431761238139e-07 BR00117021 GRIN2A final orf I24 A549 48 4155 ADCCM +0.05696969696969697 2.093237877818614e-07 BR00117021 CYP3A4 final orf K22 A549 48 4950 ADCCM +0.059643377540688054 2.170459362341564e-07 BR00117021 CTSG final orf F19 A549 48 4500 ADCCM +0.05641025744166528 2.368926247891072e-07 BR00117021 GAA final orf N15 A549 48 4985 ADCCM +0.0497093219621816 3.1056141335613425e-07 BR00117021 HCK final orf O01 A549 48 6310 ADCCM +0.06315221695098099 3.2854831139521083e-07 BR00117021 AURKB final orf L19 A549 48 3890 ADCCM +0.0559552820248079 3.368722582558986e-07 BR00117021 GJB4 final orf P08 A549 48 4955 ADCCM +0.056431011973038674 4.428113406064342e-07 BR00117021 TUBB3 final orf G06 A549 48 4790 ADCCM 0.20012050589953337 2.378832342767353e-64 BR00117021 DYRK1B final orf M12 A549 48 3650 Anaphase 0.1790611677724551 7.090052907259205e-59 BR00117020 DYRK1B final orf M12 A549 48 4170 Anaphase 0.17247764655314599 1.314612130959064e-55 BR00117021 DYRK1B final orf G13 A549 48 4245 Anaphase @@ -1219,6 +12109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.08062466136850444 2.4336501799652376e-14 BR00117021 KCNN1 final orf A01 A549 48 4910 Anaphase 0.07265127539266039 6.427736731759296e-14 BR00117021 KCNMA1 final orf G01 A549 48 5860 Anaphase 0.08121825887550876 2.693392645360323e-13 BR00117020 CACNB4 final orf A18 A549 48 4470 Anaphase +0.07436085602437209 3.7609707007292197e-13 BR00117021 TNNC1 final orf G07 A549 48 5290 Anaphase +0.07363818101296735 3.7828444998442703e-13 BR00117020 BAX final orf K17 A549 48 5385 Anaphase +0.06853097407339832 3.910909010293913e-13 BR00117021 P2RY12 final orf B01 A549 48 6220 Anaphase +0.07349624060150375 6.465651592778002e-13 BR00117020 ABL1 final orf C01 A549 48 5320 Anaphase +0.07146666666666666 6.522171843974617e-13 BR00117021 CSK final orf P05 A549 48 5625 Anaphase +0.07051469314067067 1.0114204950987277e-12 BR00117021 KCNQ2 final orf K01 A549 48 5670 Anaphase +0.07257142857142856 1.920859573676896e-12 BR00117021 NAMPT final orf L06 A549 48 5250 Anaphase +0.06380083743544997 2.0652950777952174e-12 BR00117020 HSP90AB1 final orf P01 A549 48 6750 Anaphase +0.06827333022710026 2.4779558019964065e-12 BR00117021 BTK final orf N01 A549 48 5855 Anaphase +0.0670558798999166 3.856344682352545e-12 BR00117021 RET final orf E03 A549 48 5995 Anaphase +0.06891280642119381 7.589810588431463e-12 BR00117021 CACNB4 final orf M01 A549 48 5525 Anaphase +0.06718559901293071 2.6581030336508774e-11 BR00117020 TUBB3 final orf G06 A549 48 5525 Anaphase +0.06727471002280162 2.7856210120525858e-11 BR00117020 EDNRB final orf M08 A549 48 5500 Anaphase +0.06585953035503721 3.398516870954338e-11 BR00117021 NTRK1 final orf P02 A549 48 5690 Anaphase +0.06929785372573109 4.7412982216504544e-11 BR00117020 PTK2B final orf J18 A549 48 5080 Anaphase +0.07039651381121163 5.342788100731147e-11 BR00117021 CA5A final orf B02 A549 48 4890 Anaphase +0.06422976501305483 1.003966476705253e-10 BR00117021 S1PR1 final orf L01 A549 48 5745 Anaphase +0.06605528738849448 1.182694913128686e-10 BR00117021 CSK final orf B04 A549 48 5370 Anaphase +0.06738125190125811 1.4024482675563412e-10 BR00117020 HTR2C final orf G21 A549 48 5135 Anaphase +0.06641000962463908 2.2097598986307904e-10 BR00117021 FPR1 final orf L04 A549 48 5195 Anaphase +0.06334143607988502 2.40274496456722e-10 BR00117021 AKR1C1 final orf I01 A549 48 5675 Anaphase +0.06376538613167462 2.912794576870364e-10 BR00117021 GPR119 final orf N02 A549 48 5550 Anaphase +0.06286354810021018 3.1836693365227034e-10 BR00117021 ADA final orf P03 A549 48 5700 Anaphase +0.06361185983827493 3.277941093034422e-10 BR00117020 NTRK1 final orf D01 A549 48 5565 Anaphase +0.06273784752688712 4.0445900822582306e-10 BR00117021 KCNQ2 final orf K02 A549 48 5650 Anaphase +0.06368427429839865 4.742071664957589e-10 BR00117021 TUBB3 final orf K05 A549 48 5445 Anaphase +0.06095097413083582 6.5331665662717e-10 BR00117021 HSP90AB1 final orf P01 A549 48 5855 Anaphase +0.06107032350330883 8.442864208944113e-10 BR00117020 TUBB3 final orf K05 A549 48 5760 Anaphase +0.059540361006452186 2.3047071495952054e-09 BR00117020 GPR119 final orf N02 A549 48 5785 Anaphase +0.07024865240827682 3.91056406960837e-09 BR00117021 IMPDH1 final orf N20 A549 48 4050 Anaphase +0.06518557003980481 4.5055002515938996e-09 BR00117020 KCNJ1 final orf M03 A549 48 4660 Anaphase +0.06327575575784238 4.52998292587254e-09 BR00117021 GUCY1B1 final orf F05 A549 48 4955 Anaphase +0.07206266318537859 4.537929709655262e-09 BR00117020 ANXA1 final orf D23 A549 48 3830 Anaphase +0.06171971344908863 4.784063890489968e-09 BR00117020 USP1 final orf E12 A549 48 5195 Anaphase +0.05725964856399639 5.674088198145959e-09 BR00117021 KDR final orf O02 A549 48 5985 Anaphase +0.06221550890803569 9.252775666504922e-09 BR00117021 SCNN1G final orf A04 A549 48 4930 Anaphase +0.05757637871476767 1.090711153858703e-08 BR00117021 GLRA3 final orf K04 A549 48 5720 Anaphase +0.061652104668754495 1.1382226585165593e-08 BR00117020 EDNRB final orf K11 A549 48 4975 Anaphase +0.05938508497068289 1.4461190785574155e-08 BR00117020 S100B final orf I09 A549 48 5295 Anaphase +0.05815808958644097 1.8900075883465073e-08 BR00117021 GAA final orf N04 A549 48 5440 Anaphase +0.060716530789077044 2.0508511061103714e-08 BR00117021 P3H1 final orf P24 A549 48 4970 Anaphase +0.06033512699207452 2.3186805458885273e-08 BR00117021 PTGIS final orf H13 A549 48 5010 Anaphase +0.06281141300358706 2.5427227318901674e-08 BR00117020 PRKCE final orf J19 A549 48 4580 Anaphase +0.05769021012121586 2.9439875641895978e-08 BR00117020 HRH4 final orf O05 A549 48 5400 Anaphase +0.05312600609789944 3.6831376558923215e-08 BR00117020 COMT final orf P09 A549 48 6295 Anaphase +0.06194111232279171 4.5412753231071304e-08 BR00117020 KCTD16 final orf M22 A549 48 4585 Anaphase +0.0651878686192275 4.7186360760179954e-08 BR00117021 ASIC1 final orf L21 A549 48 4105 Anaphase +0.05861999962770611 4.959502267724353e-08 BR00117020 SSTR2 final orf J01 A549 48 5080 Anaphase +0.06855688029449013 5.055608345288945e-08 BR00117021 CACNB4 final orf A18 A549 48 3705 Anaphase +0.057152551753799186 5.158014240277461e-08 BR00117021 FFAR4 final orf I16 A549 48 5325 Anaphase +0.0637315376303957 5.159349677678447e-08 BR00117021 TBXAS1 final orf J24 A549 48 4290 Anaphase +0.0559173167598728 5.648767290750835e-08 BR00117020 PIK3CG final orf I03 A549 48 5535 Anaphase +0.06081811772031353 5.867246002632157e-08 BR00117021 AVPR1A final orf H22 A549 48 4675 Anaphase +0.06279139076250603 6.485213083565917e-08 BR00117021 PDE7A final orf F20 A549 48 4355 Anaphase +0.05708848715509039 7.239838454416527e-08 BR00117020 LPAR1 final orf B05 A549 48 5255 Anaphase +0.05962359178802367 1.0242489487791207e-07 BR00117020 SLC7A11 final orf G24 A549 48 4705 Anaphase +0.05957238826147543 1.274664844774828e-07 BR00117021 KRAS final orf F08 A549 48 4650 Anaphase +0.0564553027673472 1.3976071037743577e-07 BR00117021 LPAR1 final orf B05 A549 48 5160 Anaphase +0.051935828610348976 2.0829147086220736e-07 BR00117021 OPRL1 final orf O16 A549 48 5940 Anaphase +0.05373406193078324 2.5947839411346265e-07 BR00117020 ICAM1 final orf I15 A549 48 5490 Anaphase +0.06046613467220773 2.7337224303996736e-07 BR00117021 PNLIP final orf L22 A549 48 4295 Anaphase +0.0559016535964233 3.119904608655222e-07 BR00117020 HSP90AA1 final orf C14 A549 48 4985 Anaphase +0.057374408354977965 3.638963449545727e-07 BR00117020 MET final orf C08 A549 48 4700 Anaphase +0.0527980829738991 3.7726632051543996e-07 BR00117021 CCR1 final orf P17 A549 48 5535 Anaphase +0.05444015444015444 4.082450314550756e-07 BR00117021 AGER final orf H09 A549 48 5175 Anaphase +0.05694537716027489 4.341936225233117e-07 BR00117020 ELANE final orf D19 A549 48 4715 Anaphase +0.049538096017453445 4.6603435153851735e-07 BR00117020 DHH final orf G05 A549 48 6190 Anaphase +0.05773744454918692 5.75025613348355e-07 BR00117020 CHRM3 final orf A11 A549 48 4510 Anaphase +0.05896232766049117 7.918557609500447e-07 BR00117021 VEGFA final orf B09 A549 48 4220 Anaphase +0.05370321789454055 9.261970434788541e-07 BR00117020 TNNC1 final orf G07 A549 48 5030 Anaphase +0.05435458819316341 1.003517401860226e-06 BR00117020 PDE7A final orf J11 A549 48 4900 Anaphase +0.05825081861084255 1.280307306851967e-06 BR00117021 HTR2C final orf G21 A549 48 4195 Anaphase +0.05369491056610732 1.2882234511592215e-06 BR00117020 DDR2 final orf M02 A549 48 4930 Anaphase +0.0527589130946416 1.53026479914827e-06 BR00117021 HPGDS final orf O21 A549 48 5035 Anaphase +0.05298281092012133 1.86277032683082e-06 BR00117020 NAMPT final orf D13 A549 48 4945 Anaphase +0.05107339974857497 1.9175320035136e-06 BR00117021 CACNA2D3 final orf P19 A549 48 5280 Anaphase +0.054846234229268966 2.290456447328812e-06 BR00117021 PARP3 final orf H21 A549 48 4525 Anaphase +0.05275506622399263 2.7982499831988815e-06 BR00117020 COMT final orf B10 A549 48 4825 Anaphase +0.049544098769792454 2.81303863064773e-06 BR00117020 CATSPER4 final orf P07 A549 48 5470 Anaphase +0.05047619047619047 3.0896470300337493e-06 BR00117021 KCNH7 final orf O07 A549 48 5250 Anaphase +0.05789473684210526 3.093091515414881e-06 BR00117020 BRAF final orf I10 A549 48 3990 Anaphase +0.05213573801613669 3.1020161840708183e-06 BR00117021 IL1B final orf G08 A549 48 4900 Anaphase +0.050861760742479126 3.509974705201946e-06 BR00117020 PAK4 final orf G10 A549 48 5095 Anaphase +0.052554744525547446 3.5259208085838146e-06 BR00117020 ELANE final orf H08 A549 48 4795 Anaphase +0.04712745121574088 3.5277443118711772e-06 BR00117020 CCR1 final orf P17 A549 48 5950 Anaphase +0.051275876378969285 3.5748688521146725e-06 BR00117021 FGF1 final orf F03 A549 48 5020 Anaphase +0.047361616820789675 3.739006386148731e-06 BR00117020 P2RY12 final orf B01 A549 48 5865 Anaphase +0.050865800865800864 3.9973268870899605e-06 BR00117020 CHRM3 final orf A10 A549 48 5060 Anaphase +0.05234622141588388 4.127354090006464e-06 BR00117020 ADH1C final orf M23 A549 48 4755 Anaphase +0.04822986513994124 4.717700352887084e-06 BR00117021 ALDH2 final orf P13 A549 48 5545 Anaphase 0.1782353581577989 4.560624855366165e-51 BR00117021 DYRK1B final orf M12 A549 48 3650 Apoptosis 0.14704223179305811 9.699536341807854e-40 BR00117020 DYRK1B final orf M12 A549 48 4170 Apoptosis 0.1149812734082397 3.7623678078176776e-31 BR00117021 HPGDS final orf O24 A549 48 5340 Apoptosis @@ -1229,6 +12209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.11311046011373778 2.400021408774828e-25 BR00117020 CACNB4 final orf A18 A549 48 4470 Apoptosis 0.1176039119804401 4.788104690514709e-25 BR00117021 CHRM3 final orf A10 A549 48 4090 Apoptosis 0.09763554783243963 8.948895769948957e-25 BR00117021 BTK final orf N01 A549 48 5855 Apoptosis +0.10541666666666667 1.2437400994039083e-23 BR00117021 RNASE1 final orf G17 A549 48 4800 Apoptosis +0.09459111430462519 1.8621051857426765e-23 BR00117020 TUBB4B final orf E07 A549 48 5910 Apoptosis +0.1190230907026949 2.4778921847057772e-23 BR00117021 CACNB4 final orf A18 A549 48 3705 Apoptosis +0.10538793103448275 7.596348339414238e-23 BR00117020 CACNG1 final orf A16 A549 48 4640 Apoptosis +0.09907605474085719 4.823082068277413e-22 BR00117020 CHRM3 final orf A10 A549 48 5060 Apoptosis +0.10533971163084742 1.3680620013029397e-21 BR00117020 CCR1 final orf F24 A549 48 4380 Apoptosis +0.09028255731481419 3.0652304509658736e-21 BR00117021 HSP90AB1 final orf P01 A549 48 5855 Apoptosis +0.11520423035974559 4.41871049049253e-21 BR00117021 GHSR final orf C24 A549 48 3565 Apoptosis +0.0968421052631579 8.434231680824578e-20 BR00117020 CYP2A6 final orf A20 A549 48 4750 Apoptosis +0.08685813751087902 2.8552985716088423e-19 BR00117021 S1PR1 final orf L01 A549 48 5745 Apoptosis +0.095 2.8904139989844735e-19 BR00117020 AKR1C1 final orf A24 A549 48 4800 Apoptosis +0.08933333333333333 1.209789387834645e-18 BR00117021 KCNH7 final orf O07 A549 48 5250 Apoptosis +0.09834433721009658 2.6538746723699904e-18 BR00117021 DYRK1B final orf G13 A549 48 4245 Apoptosis +0.10753338654167789 1.0043710413179377e-17 BR00117021 AKR1C1 final orf A24 A549 48 3435 Apoptosis +0.08363431058888988 2.8883000792794094e-17 BR00117021 ATM final orf E11 A549 48 5530 Apoptosis +0.0812130618953687 1.4472198810120265e-16 BR00117020 ATP5F1D final orf G14 A549 48 5610 Apoptosis +0.08013876843018214 1.6062259017785048e-16 BR00117021 HRH4 final orf O05 A549 48 5765 Apoptosis +0.0802583110996224 1.9938855206174276e-16 BR00117021 ADA final orf P03 A549 48 5700 Apoptosis +0.0871900826446281 2.0084189421318092e-16 BR00117020 CHRM2 final orf B03 A549 48 4840 Apoptosis +0.08584670350490738 3.454135730539985e-16 BR00117020 PDE7A final orf J11 A549 48 4900 Apoptosis +0.08070437023475455 5.424586907966396e-16 BR00117021 CCND1 final orf P16 A549 48 5480 Apoptosis +0.09494684724042522 7.550722962634594e-16 BR00117020 CDK4 final orf B21 A549 48 3920 Apoptosis +0.07867891081701142 9.55094629942447e-16 BR00117021 AKR1C1 final orf I01 A549 48 5675 Apoptosis +0.08420325116043219 9.732223285780952e-16 BR00117020 RET final orf E03 A549 48 4960 Apoptosis +0.07770937781421794 1.7402237210836868e-15 BR00117021 GLRA3 final orf K04 A549 48 5720 Apoptosis +0.0801078818080602 1.855974210463987e-15 BR00117020 BAX final orf K17 A549 48 5385 Apoptosis +0.08181235004816115 3.77906694486584e-15 BR00117021 ADORA2A final orf O23 A549 48 5050 Apoptosis +0.07769103665845313 5.6988485053919126e-15 BR00117021 CCR1 final orf P17 A549 48 5535 Apoptosis +0.09069191650901048 4.269129496606099e-14 BR00117021 P2RY12 final orf B24 A549 48 3805 Apoptosis +0.08401735243718911 5.310760792720489e-14 BR00117021 SLC29A1 final orf L20 A549 48 4405 Apoptosis +0.07835484785013146 8.845868921390129e-14 BR00117020 HSP90AA1 final orf C14 A549 48 4985 Apoptosis +0.08375624700844646 1.3544479621754304e-13 BR00117021 SLC7A11 final orf G24 A549 48 4315 Apoptosis +0.07792158883247595 1.4804382088801813e-13 BR00117021 GUCY1B1 final orf F05 A549 48 4955 Apoptosis +0.0791897426672801 1.4933314723792393e-13 BR00117020 HDAC6 final orf E20 A549 48 4810 Apoptosis +0.0783764923237577 1.5691220926880602e-13 BR00117021 CDK2 final orf L03 A549 48 4890 Apoptosis +0.07623666343355966 1.8956634946908723e-13 BR00117020 RET final orf K10 A549 48 5155 Apoptosis +0.08074398249452953 2.2323049556823854e-13 BR00117021 TNNC1 final orf M18 A549 48 4570 Apoptosis +0.07942023174384501 2.392423165047885e-13 BR00117020 GHSR final orf C24 A549 48 4705 Apoptosis +0.07796962908029152 3.7007363420609757e-13 BR00117020 TNF final orf C18 A549 48 4815 Apoptosis +0.07609938433602265 4.196865267116684e-13 BR00117021 MET final orf C03 A549 48 5015 Apoptosis +0.0751395668174357 5.011064408738717e-13 BR00117020 VEGFA final orf B09 A549 48 5130 Apoptosis +0.07675980145022186 5.553655309209959e-13 BR00117021 RPL3 final orf G09 A549 48 4895 Apoptosis +0.0781171804176926 1.2712679831784067e-12 BR00117020 PRKCE final orf J19 A549 48 4580 Apoptosis +0.07647047796991278 1.2899066601515708e-12 BR00117020 SLCO2B1 final orf A02 A549 48 4790 Apoptosis +0.08468087103497374 1.4590401435002505e-12 BR00117021 MET final orf C08 A549 48 3890 Apoptosis +0.08609591991601337 1.6676866343605459e-12 BR00117021 UGT1A9 final orf E24 A549 48 3745 Apoptosis +0.06378799602684623 2.138709647552855e-12 BR00117020 HSP90AB1 final orf P01 A549 48 6750 Apoptosis +0.07033014339410143 2.1985714819030307e-12 BR00117021 SSTR2 final orf J01 A549 48 5540 Apoptosis +0.0704322442636019 2.258289261683901e-12 BR00117021 CACNB4 final orf M01 A549 48 5525 Apoptosis +0.07122774133083412 3.446077014118927e-12 BR00117021 CATSPER4 final orf P07 A549 48 5335 Apoptosis +0.06604517521527638 4.750766944298811e-12 BR00117020 PTGIR final orf C07 A549 48 6120 Apoptosis +0.07904102434355505 5.073999770666203e-12 BR00117020 S100B final orf M20 A549 48 4255 Apoptosis +0.07560421073049907 5.625032069467165e-12 BR00117021 MMP2 final orf F06 A549 48 4630 Apoptosis +0.07347421787900871 5.674534640171545e-12 BR00117021 PDE4D final orf B22 A549 48 4905 Apoptosis +0.0804592507025225 5.7840723047709945e-12 BR00117020 P2RY12 final orf B24 A549 48 4085 Apoptosis +0.06926563916591115 6.333799895254476e-12 BR00117021 S1PR4 final orf M17 A549 48 5515 Apoptosis +0.07373822357975304 8.726058859932617e-12 BR00117021 TUBB3 final orf G06 A549 48 4790 Apoptosis +0.07566972127563736 9.708327065671176e-12 BR00117020 ATM final orf E11 A549 48 4535 Apoptosis +0.07085833292011702 9.812563752190938e-12 BR00117020 KCNH7 final orf O07 A549 48 5160 Apoptosis +0.06779964221824687 1.3608363817045003e-11 BR00117020 S1PR4 final orf K18 A549 48 5590 Apoptosis +0.0739084132055378 1.4257566095992854e-11 BR00117021 BRAF final orf C05 A549 48 4695 Apoptosis +0.07138650600351827 3.206141657448853e-11 BR00117021 HDAC6 final orf K03 A549 48 4865 Apoptosis +0.06998011928429423 3.9388573231337327e-11 BR00117021 BAX final orf K17 A549 48 5030 Apoptosis +0.06968064549668758 4.0742275746966964e-11 BR00117021 MAPK8 final orf I13 A549 48 5050 Apoptosis +0.0668488160291439 4.357950236579382e-11 BR00117020 ICAM1 final orf I15 A549 48 5490 Apoptosis +0.07161778147823018 6.321921359336913e-11 BR00117020 MET final orf C08 A549 48 4700 Apoptosis +0.06428852630134459 7.773962560112949e-11 BR00117021 PTPN2 final orf O15 A549 48 5775 Apoptosis +0.06696230391882566 1.5217219266150955e-10 BR00117021 AGER final orf H09 A549 48 5175 Apoptosis +0.07549019607843137 1.5663387053920712e-10 BR00117021 FPR1 final orf D21 A549 48 4080 Apoptosis +0.06290235831959498 1.678835709464455e-10 BR00117021 PIK3CG final orf I03 A549 48 5850 Apoptosis +0.07468586715142511 1.9651143973114498e-10 BR00117021 ASIC1 final orf L21 A549 48 4105 Apoptosis +0.06676858211872452 2.7144031966516957e-10 BR00117020 SSTR2 final orf J01 A549 48 5080 Apoptosis +0.0697524219590958 3.014065802024794e-10 BR00117021 PLA2G1B final orf E06 A549 48 4645 Apoptosis +0.06724524409555308 3.123412384249123e-10 BR00117020 EDNRB final orf K11 A549 48 4975 Apoptosis +0.07369806052090093 3.929925985212657e-10 BR00117021 TNF final orf C18 A549 48 4095 Apoptosis +0.061234186360406485 4.038851186568756e-10 BR00117021 CACNA2D3 final orf L02 A549 48 5940 Apoptosis +0.06779270913280364 4.732658963622573e-10 BR00117021 FGF1 final orf F22 A549 48 4815 Apoptosis +0.06129394059608369 4.985117149887994e-10 BR00117020 USP1 final orf G11 A549 48 5870 Apoptosis +0.06772486772486773 7.634988522217034e-10 BR00117021 CLK1 final orf D08 A549 48 4725 Apoptosis +0.07069767441860465 9.129134188973516e-10 BR00117021 CATSPER4 final orf D24 A549 48 4300 Apoptosis +0.06866540503255572 1.4402847102180378e-09 BR00117020 CHRM2 final orf B08 A549 48 4450 Apoptosis +0.0675953842096635 1.4568642032373386e-09 BR00117021 CYP2A6 final orf A15 A549 48 4585 Apoptosis +0.06519785527095277 1.7923677789628749e-09 BR00117021 CA5A final orf B02 A549 48 4890 Apoptosis +0.05980418933649746 2.1683908778978416e-09 BR00117020 TUBB3 final orf K05 A549 48 5760 Apoptosis +0.06040574147713029 2.246227571567255e-09 BR00117021 UGT1A9 final orf O09 A549 48 5630 Apoptosis +0.06324816133102196 2.276078752751806e-09 BR00117021 USP1 final orf G11 A549 48 5130 Apoptosis +0.058173164237237465 3.0162019727986774e-09 BR00117021 KDR final orf O02 A549 48 5985 Apoptosis +0.0640932011391361 3.107226951944689e-09 BR00117020 KCNN4 final orf A06 A549 48 4910 Apoptosis +0.06252375993785227 3.118642811376305e-09 BR00117020 OPRM1 final orf A08 A549 48 5160 Apoptosis +0.06258503401360545 3.5001919384933174e-09 BR00117020 PRKCE final orf L14 A549 48 5145 Apoptosis 0.12265917602996254 2.110155323114162e-35 BR00117021 HPGDS final orf O24 A549 48 5340 Binuclear 0.1112713285924309 6.492726182561656e-23 BR00117020 DYRK1B final orf M12 A549 48 4170 Binuclear 0.09399477806788512 1.6858509626450355e-22 BR00117021 S1PR1 final orf L01 A549 48 5745 Binuclear @@ -1239,6 +12309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.0820418610860164 4.283731592082903e-17 BR00117021 AKR1C1 final orf I01 A549 48 5675 Binuclear 0.09149497944956038 9.404285234558844e-17 BR00117020 CACNB4 final orf A18 A549 48 4470 Binuclear 0.08615384615384615 4.14307009000883e-15 BR00117020 DYRK1B final orf G13 A549 48 4550 Binuclear +0.08635667375591807 1.3220653525029358e-14 BR00117021 PTK2B final orf J18 A549 48 4355 Binuclear +0.08198365882549728 1.367203581197793e-14 BR00117021 FFAR4 final orf C17 A549 48 4840 Binuclear +0.08014662175549832 1.4488031912102333e-14 BR00117021 ADORA2A final orf O23 A549 48 5050 Binuclear +0.07736355100754075 1.5617166669878576e-14 BR00117020 CACNG1 final orf E23 A549 48 5410 Binuclear +0.07441457068516913 2.6610886230841105e-14 BR00117021 HRH4 final orf O05 A549 48 5765 Binuclear +0.07275348675608503 3.040895217189691e-14 BR00117021 FOXM1 final orf J02 A549 48 5990 Binuclear +0.079326907941545 3.1023228623067204e-14 BR00117020 KCNN4 final orf O17 A549 48 5040 Binuclear +0.07895462845428017 6.251058475309057e-14 BR00117021 P3H1 final orf P24 A549 48 4970 Binuclear +0.07413333333333333 7.316380713147939e-14 BR00117021 CSK final orf P05 A549 48 5625 Binuclear +0.07697005304832859 3.2192054564823584e-13 BR00117020 RET final orf E03 A549 48 4960 Binuclear +0.07004607955466252 3.878938787102831e-13 BR00117021 OPRL1 final orf O16 A549 48 5940 Binuclear +0.0728102976169764 4.707811789913662e-13 BR00117021 ADA final orf P04 A549 48 5470 Binuclear +0.07285453155018372 2.1259526276951864e-12 BR00117021 COMT final orf P09 A549 48 5175 Binuclear +0.07432726004518411 3.3378583498826336e-12 BR00117021 RPL3 final orf G09 A549 48 4895 Binuclear +0.06855038376306409 3.66184391018878e-12 BR00117020 GLRA3 final orf K04 A549 48 5735 Binuclear +0.07252077035745576 6.10809132988382e-12 BR00117021 MET final orf C03 A549 48 5015 Binuclear +0.07028112449799197 4.0770546067015986e-11 BR00117020 TGFBR1 final orf I23 A549 48 4980 Binuclear +0.06395587631285572 4.355636324513622e-11 BR00117021 KDR final orf O02 A549 48 5985 Binuclear +0.06964251430932264 4.4347780614794506e-11 BR00117021 RPL3 final orf K12 A549 48 5035 Binuclear +0.07036094023794057 5.007293099372793e-11 BR00117021 KCNN1 final orf A01 A549 48 4910 Binuclear +0.06732325702688606 1.68777249800399e-10 BR00117021 SCNN1G final orf O03 A549 48 5090 Binuclear +0.06276848246752488 1.7791422635856272e-10 BR00117021 PIK3CG final orf I03 A549 48 5850 Binuclear +0.06907962771458118 1.8783777307563103e-10 BR00117020 CDK2 final orf J04 A549 48 4835 Binuclear +0.06653846153846153 1.9776132411820492e-10 BR00117020 MAPK8 final orf I13 A549 48 5200 Binuclear +0.06592915214866435 2.2507068925393089e-10 BR00117020 CACNA2D3 final orf P19 A549 48 5250 Binuclear +0.06321421322745062 2.3757515187740177e-10 BR00117021 NTRK1 final orf P02 A549 48 5690 Binuclear +0.06492085632176772 2.495797119983557e-10 BR00117020 BAX final orf K17 A549 48 5385 Binuclear +0.06265155826908815 2.734159392961167e-10 BR00117021 PTPN2 final orf O15 A549 48 5775 Binuclear +0.06571428571428571 2.8105712378459217e-10 BR00117021 KCNH7 final orf O07 A549 48 5250 Binuclear +0.07024133543126711 3.6422181775419254e-10 BR00117020 PNLIP final orf J09 A549 48 4530 Binuclear +0.06771819137749738 6.681498183519871e-10 BR00117021 TUBB4B final orf E04 A549 48 4755 Binuclear +0.07035453068812378 7.14124610237239e-10 BR00117020 CCR1 final orf F24 A549 48 4380 Binuclear +0.06052486391752397 9.397799028171309e-10 BR00117021 HSP90AB1 final orf P01 A549 48 5855 Binuclear +0.06153338199860231 1.5605113255814635e-09 BR00117021 CACNB4 final orf M01 A549 48 5525 Binuclear +0.06759385281608254 1.8178605883925138e-09 BR00117020 ATM final orf E11 A549 48 4535 Binuclear +0.07336814621409922 2.1904926501647545e-09 BR00117020 ANXA1 final orf D23 A549 48 3830 Binuclear +0.05939351579749972 3.166254592649321e-09 BR00117021 GLRA3 final orf K04 A549 48 5720 Binuclear +0.05992714025500911 5.421457754669171e-09 BR00117020 ICAM1 final orf I15 A549 48 5490 Binuclear +0.053878160276145164 5.621363038203838e-09 BR00117020 HSP90AB1 final orf P01 A549 48 6750 Binuclear +0.06437029063509149 8.657780435212342e-09 BR00117021 PLA2G1B final orf E06 A549 48 4645 Binuclear +0.06927671680292913 1.2400967895418076e-08 BR00117020 CDK4 final orf B21 A549 48 3920 Binuclear +0.06622746742682757 1.2987654231986918e-08 BR00117021 GABRB2 final orf C19 A549 48 4285 Binuclear +0.06157982391345241 1.605970836741588e-08 BR00117020 CATSPER4 final orf D24 A549 48 4895 Binuclear +0.0572168235264111 2.0909945383946323e-08 BR00117020 CDC25A final orf M04 A549 48 5600 Binuclear +0.059094252398124505 2.1205101501431814e-08 BR00117021 TUBB4B final orf E07 A549 48 5235 Binuclear +0.05641300233569364 2.409020239785401e-08 BR00117021 ADA final orf P03 A549 48 5700 Binuclear +0.06330969497319723 2.638266154232191e-08 BR00117020 CHRM3 final orf A11 A549 48 4510 Binuclear +0.05996348950472633 2.865364982378339e-08 BR00117021 PTGIS final orf H13 A549 48 5010 Binuclear +0.05810684161199625 2.980966760890508e-08 BR00117021 CATSPER4 final orf P07 A549 48 5335 Binuclear +0.0660197574165128 3.393014001933752e-08 BR00117020 P2RY12 final orf B24 A549 48 4085 Binuclear +0.0619468204059105 4.194893343112307e-08 BR00117020 PRKCE final orf J19 A549 48 4580 Binuclear +0.061488072861467825 5.158560332523948e-08 BR00117021 PTGIR final orf E16 A549 48 4605 Binuclear +0.05763436946339923 5.3161006857335817e-08 BR00117021 MAPK14 final orf G15 A549 48 5230 Binuclear +0.059371833839918946 5.525708705862868e-08 BR00117020 BTK final orf P10 A549 48 4935 Binuclear +0.05988843397887091 7.352564866139936e-08 BR00117021 S1PR2 final orf B19 A549 48 4765 Binuclear +0.05662299025643581 7.656459916334194e-08 BR00117021 FLT3 final orf K13 A549 48 5300 Binuclear +0.06055769424456406 7.807773687065995e-08 BR00117021 MMP2 final orf F06 A549 48 4630 Binuclear +0.05767209202476007 7.825023430178e-08 BR00117020 CA14 final orf J14 A549 48 5105 Binuclear +0.05701244322132955 8.791137965798747e-08 BR00117021 ICAM1 final orf I08 A549 48 5200 Binuclear +0.058884297520661155 1.0214701505075741e-07 BR00117020 CHRM2 final orf B03 A549 48 4840 Binuclear +0.05430567057245315 1.045254931948218e-07 BR00117021 RET final orf K10 A549 48 5660 Binuclear +0.05505159288401866 1.2442727276484874e-07 BR00117021 KCNN4 final orf O17 A549 48 5450 Binuclear +0.05389704146098572 1.2951771865960864e-07 BR00117021 KCNQ2 final orf K01 A549 48 5670 Binuclear +0.05374109928404904 2.0667301594428854e-07 BR00117021 GPR119 final orf N02 A549 48 5550 Binuclear +0.055290753098188754 2.1603614350011534e-07 BR00117020 HDAC3 final orf N06 A549 48 5245 Binuclear +0.05377400329509128 2.559948456145359e-07 BR00117020 FOXM1 final orf P15 A549 48 5470 Binuclear +0.06060795015132122 3.02354785157856e-07 BR00117020 S100B final orf M20 A549 48 4255 Binuclear +0.05646648526168171 3.164768436831072e-07 BR00117021 CDK2 final orf L03 A549 48 4890 Binuclear +0.05348771250771618 3.2122916198873944e-07 BR00117021 ADH1C final orf O04 A549 48 5445 Binuclear +0.0553112376910333 3.376290947931869e-07 BR00117020 PTK2B final orf J18 A549 48 5080 Binuclear +0.05582329317269076 3.6177693121395135e-07 BR00117020 CYP1A2 final orf F21 A549 48 4980 Binuclear +0.052791790919484174 4.326827248395721e-07 BR00117021 CCND1 final orf P16 A549 48 5480 Binuclear +0.061687382168352976 6.923007273116703e-07 BR00117021 PARP3 final orf J20 A549 48 3895 Binuclear +0.0567063597601256 7.31578459782257e-07 BR00117020 KCNK1 final orf C22 A549 48 4580 Binuclear +0.05328337850323259 9.21986236900598e-07 BR00117020 VEGFA final orf B09 A549 48 5130 Binuclear +0.05581896551724138 1.0466441738591177e-06 BR00117020 CACNG1 final orf A16 A549 48 4640 Binuclear +0.051914098972922505 1.0740084814661633e-06 BR00117020 LCK final orf H01 A549 48 5355 Binuclear +0.05180554875960268 1.0889499762754766e-06 BR00117020 SIRT2 final orf A07 A549 48 5350 Binuclear +0.05080486407848012 1.170130092176766e-06 BR00117021 ALDH2 final orf P13 A549 48 5545 Binuclear +0.061775339733200346 1.348662903357985e-06 BR00117021 CACNB4 final orf A18 A549 48 3705 Binuclear +0.058151138555442766 1.7009175224144288e-06 BR00117021 ASIC1 final orf L21 A549 48 4105 Binuclear +0.05022858392776372 1.7410645239413762e-06 BR00117020 GPR55 final orf F13 A549 48 5505 Binuclear +0.049183316579186294 2.350867032014826e-06 BR00117021 NTRK1 final orf D01 A549 48 5615 Binuclear +0.05249800833657847 2.449246028107941e-06 BR00117020 KCNN4 final orf A06 A549 48 4910 Binuclear +0.053125 2.6033951420767135e-06 BR00117021 RNASE1 final orf G17 A549 48 4800 Binuclear +0.055845685363055377 2.869446241242721e-06 BR00117020 AURKB final orf L19 A549 48 4290 Binuclear +0.049017860227086825 3.1149250592169713e-06 BR00117021 SSTR2 final orf J01 A549 48 5540 Binuclear +0.04908786835579995 3.2544936629113694e-06 BR00117020 SCNN1G final orf O03 A549 48 5515 Binuclear +0.04985941893158388 3.461826109004476e-06 BR00117020 BTK final orf N01 A549 48 5335 Binuclear +0.05244769253146112 3.5595838384486803e-06 BR00117021 TUBB3 final orf G06 A549 48 4790 Binuclear 0.09222581550546412 1.2498692694552052e-15 BR00117021 TNF final orf C18 A549 48 4095 Elongated 0.07776748859566643 1.7088112413442394e-13 BR00117021 GUCY1B1 final orf F05 A549 48 4955 Elongated 0.0843520782396088 4.455980144206594e-13 BR00117021 CHRM3 final orf A10 A549 48 4090 Elongated @@ -1249,6 +12409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.07132725430597771 2.4488223197764618e-11 BR00117020 BTK final orf P10 A549 48 4935 Elongated 0.07178073126106316 2.946896276690474e-11 BR00117020 TNF final orf C18 A549 48 4815 Elongated 0.07353243442730091 4.0209966081610055e-11 BR00117020 ATM final orf E11 A549 48 4535 Elongated +0.07357520204317251 1.9633648801810603e-10 BR00117021 DYRK1B final orf G13 A549 48 4245 Elongated +0.06357077462465868 3.1807789032662835e-10 BR00117020 ADH1C final orf O04 A549 48 5575 Elongated +0.0760444783145692 1.2287356548341892e-09 BR00117021 DYRK1B final orf M12 A549 48 3650 Elongated +0.0676894547932959 2.0269588471151595e-09 BR00117020 CHRM3 final orf A11 A549 48 4510 Elongated +0.06156163857095867 2.3440145065335314e-09 BR00117020 CACNG1 final orf E23 A549 48 5410 Elongated +0.05858037997666674 2.929375903453098e-09 BR00117020 TUBB4B final orf E07 A549 48 5910 Elongated +0.06178547659123071 5.496476362914309e-09 BR00117021 SIRT2 final orf G02 A549 48 5140 Elongated +0.06554840913745096 6.103791227429526e-09 BR00117021 P3H1 final orf F23 A549 48 4540 Elongated +0.06291666666666666 1.107850798910398e-08 BR00117021 RNASE1 final orf G17 A549 48 4800 Elongated +0.058392751660477 1.243961634142793e-08 BR00117021 CACNB4 final orf M01 A549 48 5525 Elongated +0.06297881065103524 1.3983406837438425e-08 BR00117021 ATM final orf C04 A549 48 4715 Elongated +0.061149503029462926 1.4126338193993035e-08 BR00117021 PTGIS final orf H13 A549 48 5010 Elongated +0.06030556913733477 1.525256271968181e-08 BR00117021 USP1 final orf G11 A549 48 5130 Elongated +0.06126737108552111 1.8655614954348304e-08 BR00117021 IL1B final orf G08 A549 48 4900 Elongated +0.05909405579497967 2.5621003964921037e-08 BR00117020 GABRB2 final orf C19 A549 48 5190 Elongated +0.0578268876611418 2.5798380016978146e-08 BR00117020 PLK1 final orf N08 A549 48 5430 Elongated +0.058939958867829614 2.7258636463556127e-08 BR00117021 ICAM1 final orf I08 A549 48 5200 Elongated +0.059982995863780905 3.568236939399084e-08 BR00117021 SCNN1G final orf A04 A549 48 4930 Elongated +0.059638309353567016 3.654388691692262e-08 BR00117021 GAA final orf N15 A549 48 4985 Elongated +0.06666666666666667 3.93362884125153e-08 BR00117020 BRAF final orf I10 A549 48 3990 Elongated +0.05943643428237898 5.421663956989827e-08 BR00117021 KCNN1 final orf A01 A549 48 4910 Elongated +0.05780795344325897 6.547765846063272e-08 BR00117020 F10 final orf C09 A549 48 5155 Elongated +0.05693854868059263 6.686594114503071e-08 BR00117021 CACNA2D3 final orf P19 A549 48 5280 Elongated +0.05956566701137539 7.032441895232932e-08 BR00117020 CDK2 final orf J04 A549 48 4835 Elongated +0.05789021965991943 7.572021983884678e-08 BR00117021 TGFBR1 final orf I23 A549 48 5080 Elongated +0.05977413115367817 1.1351689176966956e-07 BR00117021 KRAS final orf F08 A549 48 4650 Elongated +0.058185610010427526 1.7682328499810725e-07 BR00117020 FPR1 final orf L04 A549 48 4795 Elongated +0.05645396317053643 2.265260550111182e-07 BR00117021 LYN final orf M05 A549 48 5000 Elongated +0.06079212846046529 2.2978836454966842e-07 BR00117021 SLC7A11 final orf G24 A549 48 4315 Elongated +0.05520537199508198 2.5227116040361336e-07 BR00117020 EZH2 final orf D03 A549 48 5195 Elongated +0.06031461563769717 2.7347657212426444e-07 BR00117020 ANXA1 final orf N24 A549 48 4325 Elongated +0.05600653013337459 3.070760508144523e-07 BR00117021 ALK final orf H12 A549 48 4980 Elongated +0.06313470000746949 3.362801107558098e-07 BR00117021 MET final orf C08 A549 48 3890 Elongated +0.06063646442423593 4.1436552400920813e-07 BR00117020 DYRK1B final orf M12 A549 48 4170 Elongated +0.05653204292421895 4.2024897598391597e-07 BR00117021 TUBB3 final orf G06 A549 48 4790 Elongated +0.05261271078328815 4.205838237130088e-07 BR00117021 EZH2 final orf D03 A549 48 5535 Elongated +0.0576536703121234 4.2485385061919076e-07 BR00117021 CDK7 final orf K06 A549 48 4610 Elongated +0.052509640419674715 5.275408300739393e-07 BR00117021 SSTR2 final orf D02 A549 48 5480 Elongated +0.05771243160986744 5.292889679757315e-07 BR00117021 PARP3 final orf H21 A549 48 4525 Elongated +0.05962658947251691 6.947398204588062e-07 BR00117021 GPR55 final orf H16 A549 48 4160 Elongated +0.05426868506852891 7.256665933197739e-07 BR00117021 FGF1 final orf F03 A549 48 5020 Elongated +0.052408097358432534 7.746633715837904e-07 BR00117020 PPARD final orf I12 A549 48 5350 Elongated +0.05823006975744498 7.873278835640948e-07 BR00117020 PORCN final orf N11 A549 48 4335 Elongated +0.052254597657495114 7.912308580276613e-07 BR00117021 CSK final orf B04 A549 48 5370 Elongated +0.0504006184934645 8.069235836177512e-07 BR00117021 PDPK1 final orf D06 A549 48 5775 Elongated +0.051392632524708 8.230075250801995e-07 BR00117020 NTRK1 final orf D01 A549 48 5565 Elongated +0.05712227338089307 1.2845316046027618e-06 BR00117021 PDE7A final orf F20 A549 48 4355 Elongated +0.05246441480499995 1.434179251884777e-06 BR00117020 CDK9 final orf H11 A549 48 5115 Elongated +0.049436253252385085 1.5140745879361345e-06 BR00117021 HRH4 final orf O05 A549 48 5765 Elongated +0.05262335964554981 1.9708887702580856e-06 BR00117020 VEGFA final orf P18 A549 48 4985 Elongated +0.05446716899892357 2.060869052495073e-06 BR00117021 PLA2G1B final orf E06 A549 48 4645 Elongated +0.05261036307712404 2.1818651222318263e-06 BR00117020 IL1B final orf E15 A549 48 4950 Elongated +0.05060918462980318 2.3154892322019327e-06 BR00117021 CATSPER4 final orf P07 A549 48 5335 Elongated +0.05291117813351206 2.6444183271853365e-06 BR00117021 PTPN2 final orf I02 A549 48 4825 Elongated +0.049316376321477014 3.0487185831020165e-06 BR00117021 CCND1 final orf P16 A549 48 5480 Elongated +0.04859634845810849 3.133636614116521e-06 BR00117020 GRIN2A final orf A05 A549 48 5630 Elongated +0.05112634671890304 3.190476965666177e-06 BR00117021 SIRT2 final orf A07 A549 48 5105 Elongated +0.05319711010182404 3.3923012065567756e-06 BR00117021 AVPR1A final orf H22 A549 48 4675 Elongated +0.051075300308567495 3.5375741418000954e-06 BR00117020 CHRM3 final orf A10 A549 48 5060 Elongated +0.04961274718822304 3.591378459621578e-06 BR00117020 FOXM1 final orf J02 A549 48 5350 Elongated +0.05283672859896649 3.731978236986768e-06 BR00117020 MET final orf C08 A549 48 4700 Elongated +0.06162382039303005 3.894114628409361e-06 BR00117021 AKR1C1 final orf A24 A549 48 3435 Elongated +0.05228165101740201 4.002608509178853e-06 BR00117020 KCTD16 final orf K21 A549 48 4790 Elongated +0.05060647391944025 4.065604030125327e-06 BR00117021 SCNN1G final orf O03 A549 48 5090 Elongated +0.049500615456174984 4.2715783635655676e-06 BR00117020 TGFBR1 final orf O14 A549 48 5310 Elongated +0.05340659340659341 4.600234143140899e-06 BR00117020 DYRK1B final orf G13 A549 48 4550 Elongated +0.05022639247071363 4.680702633116644e-06 BR00117020 S1PR4 final orf M17 A549 48 5125 Elongated +0.04993800043925048 5.337709072611956e-06 BR00117021 OPRM1 final orf A09 A549 48 5135 Elongated +0.04956772334293948 5.563197775579235e-06 BR00117020 AURKB final orf H10 A549 48 5205 Elongated +0.05008438661479372 5.565184235939625e-06 BR00117020 PTK2B final orf J18 A549 48 5080 Elongated +0.047224851989172485 6.722150397001747e-06 BR00117020 CSK final orf B04 A549 48 5640 Elongated +0.051318839005326626 7.936871994733668e-06 BR00117021 OPRM1 final orf A08 A549 48 4690 Elongated +0.050103781355670125 8.397921299917884e-06 BR00117021 HBB final orf C10 A549 48 4910 Elongated +0.04948901977610485 1.0040206069029713e-05 BR00117020 RET final orf E03 A549 48 4960 Elongated +0.04848312807104115 1.1653743186615393e-05 BR00117020 CA14 final orf J14 A549 48 5105 Elongated +0.05067363088431377 1.4333024343907037e-05 BR00117020 ADRA2B final orf N18 A549 48 4595 Elongated +0.04823672678599678 1.6023220725194536e-05 BR00117020 SLC29A1 final orf N03 A549 48 5010 Elongated +0.0517162471395881 1.6725078036489546e-05 BR00117021 TNF final orf C13 A549 48 4370 Elongated +0.048395414133948406 2.2063934095845038e-05 BR00117021 HDAC3 final orf N21 A549 48 4850 Elongated +0.05456919060052219 2.218731799571944e-05 BR00117020 ANXA1 final orf D23 A549 48 3830 Elongated +0.04542890194014505 2.4264827415054874e-05 BR00117020 ATM final orf C04 A549 48 5465 Elongated +0.04521251867118053 2.6668827977763855e-05 BR00117020 FOXM1 final orf P15 A549 48 5470 Elongated +0.045756717327551606 2.853686491397537e-05 BR00117020 TUBB final orf E19 A549 48 5315 Elongated +0.046285434995112416 3.301361474908653e-05 BR00117021 DNMT3A final orf H07 A549 48 5115 Elongated +0.05355339962659559 3.48048306760935e-05 BR00117021 P2RY12 final orf B24 A549 48 3805 Elongated +0.04600243271711512 3.541953781987808e-05 BR00117021 EDNRB final orf M08 A549 48 5160 Elongated +0.04758909853249476 4.056820819798925e-05 BR00117020 ALK final orf H12 A549 48 4770 Elongated +0.0442429737080689 4.0887613071798104e-05 BR00117021 S1PR4 final orf M17 A549 48 5515 Elongated +0.04641371948912548 4.242978720151744e-05 BR00117020 HSP90AA1 final orf C14 A549 48 4985 Elongated +0.05084612155865432 4.248671356406044e-05 BR00117021 NAMPT final orf D13 A549 48 4145 Elongated 0.14376616599781514 2.1326330827601598e-33 BR00117021 DYRK1B final orf M12 A549 48 3650 Grape 0.09912910845928209 1.8062202479959327e-27 BR00117021 HCK final orf O01 A549 48 6310 Grape 0.11225866218495811 1.7321474618496662e-24 BR00117020 CCR1 final orf F24 A549 48 4380 Grape @@ -1259,6 +12509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.0927763272410792 6.254956167775817e-22 BR00117021 S1PR1 final orf L01 A549 48 5745 Grape 0.1050813813417216 6.36449877105436e-22 BR00117020 CACNB4 final orf A18 A549 48 4470 Grape 0.11692615335054078 1.071763733511937e-21 BR00117021 GHSR final orf C24 A549 48 3565 Grape +0.10277904082650095 1.5407111100943079e-21 BR00117020 PRKCE final orf J19 A549 48 4580 Grape +0.11409304960443747 1.8475574005980572e-21 BR00117021 CACNB4 final orf A18 A549 48 3705 Grape +0.1063531316089711 5.3942103257957584e-21 BR00117020 DYRK1B final orf M12 A549 48 4170 Grape +0.08907833279893287 1.1454701772635202e-20 BR00117021 BTK final orf N01 A549 48 5855 Grape +0.09396762657632222 6.563578287898538e-20 BR00117020 CHRM3 final orf A10 A549 48 5060 Grape +0.09604166666666666 1.1089022299459616e-19 BR00117020 AKR1C1 final orf A24 A549 48 4800 Grape +0.08517754478860567 4.1175474638825517e-19 BR00117020 TUBB4B final orf E07 A549 48 5910 Grape +0.09953788327972919 8.388610330263638e-19 BR00117020 S100B final orf M20 A549 48 4255 Grape +0.10320970896003662 1.2421839987143234e-18 BR00117020 CDK4 final orf B21 A549 48 3920 Grape +0.09497551076742876 1.304398280111426e-18 BR00117021 MMP2 final orf F06 A549 48 4630 Grape +0.08345254013328016 3.2683821177686068e-18 BR00117021 HSP90AB1 final orf P01 A549 48 5855 Grape +0.09125 8.337041330909742e-18 BR00117021 RNASE1 final orf G17 A549 48 4800 Grape +0.09813348974870793 1.3875009581780415e-17 BR00117020 P2RY12 final orf B24 A549 48 4085 Grape +0.08270925076240856 2.087588821570842e-17 BR00117021 ADA final orf P03 A549 48 5700 Grape +0.08755117680489301 4.76566732882809e-17 BR00117020 HSP90AA1 final orf C14 A549 48 4985 Grape +0.09315403422982885 7.357124432737764e-16 BR00117021 CHRM3 final orf A10 A549 48 4090 Grape +0.08471074380165289 1.5879777128510715e-15 BR00117020 CHRM2 final orf B03 A549 48 4840 Grape +0.07718993928881179 2.3424472070974286e-15 BR00117021 HRH4 final orf O05 A549 48 5765 Grape +0.07804444444444444 2.5564032036542503e-15 BR00117021 CSK final orf P05 A549 48 5625 Grape +0.08432056897645152 5.449310288816647e-15 BR00117020 GHSR final orf C24 A549 48 4705 Grape +0.07827715355805244 1.1960983592685942e-14 BR00117021 HPGDS final orf O24 A549 48 5340 Grape +0.07549089915650718 1.6836068414438065e-14 BR00117021 AKR1C1 final orf I01 A549 48 5675 Grape +0.0810894414728911 1.8592281832971542e-14 BR00117021 RPL3 final orf G09 A549 48 4895 Grape +0.07891156462585033 2.36560263919443e-14 BR00117020 PRKCE final orf L14 A549 48 5145 Grape +0.09100381705521893 5.727711826407184e-14 BR00117021 UGT1A9 final orf E24 A549 48 3745 Grape +0.0776848155787315 6.572478499156041e-14 BR00117020 VEGFA final orf B09 A549 48 5130 Grape +0.07833001988071571 7.681005879019776e-14 BR00117021 BAX final orf K17 A549 48 5030 Grape +0.0897295838256314 8.677091021291085e-14 BR00117021 P2RY12 final orf B24 A549 48 3805 Grape +0.07638095238095238 9.714801213719854e-14 BR00117021 KCNH7 final orf O07 A549 48 5250 Grape +0.0742476341223825 1.0427968984480596e-13 BR00117021 CACNB4 final orf M01 A549 48 5525 Grape +0.07526461705717688 1.0650375949540785e-13 BR00117020 BAX final orf K17 A549 48 5385 Grape +0.08140043763676148 1.371061153509161e-13 BR00117021 TNNC1 final orf M18 A549 48 4570 Grape +0.07774083031035872 1.7605718224338123e-13 BR00117020 RET final orf E03 A549 48 4960 Grape +0.07326749200166921 2.3577329489975596e-13 BR00117021 ATM final orf E11 A549 48 5530 Grape +0.08504901960784314 2.9526154756497266e-13 BR00117021 FPR1 final orf D21 A549 48 4080 Grape +0.07965554359526372 3.083724185021323e-13 BR00117021 PLA2G1B final orf E06 A549 48 4645 Grape +0.07587349453658718 3.6009001949165284e-13 BR00117020 SSTR2 final orf J01 A549 48 5080 Grape +0.08101650773492862 8.732944121607131e-13 BR00117021 SLC7A11 final orf G24 A549 48 4315 Grape +0.07988812556228907 1.1102156132369381e-12 BR00117021 SLC29A1 final orf L20 A549 48 4405 Grape +0.07868131868131868 1.1390850478397937e-12 BR00117020 DYRK1B final orf G13 A549 48 4550 Grape +0.08268847525946106 1.1772690116771323e-12 BR00117021 ASIC1 final orf L21 A549 48 4105 Grape +0.07689439532294995 1.5280177082345746e-12 BR00117020 MET final orf C08 A549 48 4700 Grape +0.07614206345266308 1.5713357740536285e-12 BR00117021 TUBB3 final orf G06 A549 48 4790 Grape +0.07567385957568985 2.035736063027498e-12 BR00117020 HDAC6 final orf E20 A549 48 4810 Grape +0.0892392053994608 2.202416795780328e-12 BR00117021 AKR1C1 final orf A24 A549 48 3435 Grape +0.07561235356762513 4.3017132806524645e-12 BR00117021 BRAF final orf C05 A549 48 4695 Grape +0.0714742445300183 4.701531508235998e-12 BR00117020 CHEK2 final orf F07 A549 48 5225 Grape +0.07257530809360094 8.608743860399667e-12 BR00117021 GUCY1B1 final orf F05 A549 48 4955 Grape +0.07208835341365462 1.1297626667523476e-11 BR00117020 CYP1A2 final orf F21 A549 48 4980 Grape +0.07143681081006853 1.1641039743186753e-11 BR00117021 MAPK8 final orf I13 A549 48 5050 Grape +0.06975865284015288 1.1849600466579448e-11 BR00117021 FLT3 final orf K13 A549 48 5300 Grape +0.07202253057581778 1.5078762781534816e-11 BR00117020 KCNN4 final orf A06 A549 48 4910 Grape +0.08030328769894125 2.432603387416766e-11 BR00117021 MET final orf C08 A549 48 3890 Grape +0.06706889056464076 2.7318233115216078e-11 BR00117021 SSTR2 final orf J01 A549 48 5540 Grape +0.06872538545568743 4.5957177125369504e-11 BR00117020 OPRM1 final orf A08 A549 48 5160 Grape +0.07187825947176235 6.071363690684428e-11 BR00117020 AKR1B1 final orf L10 A549 48 4680 Grape +0.06847720659553831 6.24981829571322e-11 BR00117020 RET final orf K10 A549 48 5155 Grape +0.06896551724137931 6.467987451539356e-11 BR00117020 LCK final orf B18 A549 48 5075 Grape +0.07063050283552556 8.00836774138132e-11 BR00117020 SLCO2B1 final orf A02 A549 48 4790 Grape +0.07114736266769126 8.083743703861309e-11 BR00117021 CDK4 final orf P20 A549 48 4710 Grape +0.06672914714151827 9.493210364680538e-11 BR00117021 PLK1 final orf L11 A549 48 5335 Grape +0.07242524916943521 1.0179826767281256e-10 BR00117021 S100B final orf M20 A549 48 4515 Grape +0.06944278188216324 1.0240598267845915e-10 BR00117020 CATSPER4 final orf D24 A549 48 4895 Grape +0.06557377049180328 1.1025749599865615e-10 BR00117020 ICAM1 final orf I15 A549 48 5490 Grape +0.07148951097613171 1.28108238066086e-10 BR00117020 KCNK1 final orf C22 A549 48 4580 Grape +0.06628261637713434 1.4211625619041965e-10 BR00117021 TNNC1 final orf G07 A549 48 5290 Grape +0.07113062568605928 1.9265636113290018e-10 BR00117020 P3H1 final orf F23 A549 48 4555 Grape +0.06732574514191769 2.373347838004874e-10 BR00117021 MET final orf C03 A549 48 5015 Grape +0.06881861962836845 2.404362684474992e-10 BR00117020 TNF final orf C18 A549 48 4815 Grape +0.062368706990220936 3.2024077190069736e-10 BR00117021 PTPN2 final orf O15 A549 48 5775 Grape +0.06746499048507384 3.6268946684086736e-10 BR00117020 KCNN1 final orf O10 A549 48 4900 Grape +0.06634173423286453 4.1053439620291744e-10 BR00117021 ADORA2A final orf O23 A549 48 5050 Grape +0.06615429720221143 4.13567545309149e-10 BR00117020 FPR1 final orf D21 A549 48 5080 Grape +0.07090237018439387 4.85109357315144e-10 BR00117021 KCNN4 final orf A06 A549 48 4390 Grape +0.06299584535887412 6.530544064425426e-10 BR00117021 CCND1 final orf P16 A549 48 5480 Grape +0.07061701015171917 9.795052669808233e-10 BR00117021 GABRB2 final orf C19 A549 48 4285 Grape +0.0683963375790762 1.1369038266140997e-09 BR00117020 ATM final orf E11 A549 48 4535 Grape +0.07162547808178876 1.2010725850631491e-09 BR00117021 ITGB2 final orf B12 A549 48 4125 Grape +0.06298031865042174 1.275070249434494e-09 BR00117021 CATSPER4 final orf P07 A549 48 5335 Grape +0.06279786661447374 1.3047131639363475e-09 BR00117020 SIRT2 final orf A07 A549 48 5350 Grape +0.06090520874357811 1.5745438906433267e-09 BR00117021 UGT1A9 final orf O09 A549 48 5630 Grape +0.05790773196804691 1.869556525815694e-09 BR00117020 DHH final orf G05 A549 48 6190 Grape +0.06915343256013676 2.028541947598498e-09 BR00117020 ITGB2 final orf B12 A549 48 4305 Grape +0.06967927989164388 2.0464653923745152e-09 BR00117021 DYRK1B final orf G13 A549 48 4245 Grape +0.0635468969672625 3.4506316479271567e-09 BR00117020 EDNRB final orf K11 A549 48 4975 Grape +0.06452947259565667 3.565512694265541e-09 BR00117020 CDK2 final orf J04 A549 48 4835 Grape +0.06216691079645494 3.5895320123081447e-09 BR00117021 ICAM1 final orf I08 A549 48 5200 Grape +0.06608318581877491 3.650308339933236e-09 BR00117020 PLK1 final orf L11 A549 48 4580 Grape +0.06551351351351352 4.729145837121411e-09 BR00117020 UGT1A9 final orf E24 A549 48 4625 Grape +0.054011732876749916 5.177497115544522e-09 BR00117020 HSP90AB1 final orf P01 A549 48 6750 Grape 0.1301498127340824 8.11618132438324e-40 BR00117021 HPGDS final orf O24 A549 48 5340 Hole 0.1291501941713606 2.6812350779647683e-31 BR00117021 DYRK1B final orf G13 A549 48 4245 Hole 0.11605106148521184 2.3120163412168985e-27 BR00117020 PRKCE final orf J19 A549 48 4580 Hole @@ -1269,6 +12609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.09076305220883533 2.893311963653146e-18 BR00117020 CYP1A2 final orf F21 A549 48 4980 Hole 0.08467573910605984 6.700811231198872e-16 BR00117021 GUCY1B1 final orf F05 A549 48 4955 Hole 0.07974056328927828 4.7170784525312656e-14 BR00117020 KCNN4 final orf A06 A549 48 4910 Hole +0.07815488463205607 2.88837429989142e-13 BR00117021 GABRB2 final orf C06 A549 48 4830 Hole +0.08374810942245094 3.126689655961459e-13 BR00117021 HTR2C final orf G21 A549 48 4195 Hole +0.07552671208290995 3.770788527278255e-13 BR00117020 CDK9 final orf H11 A549 48 5115 Hole +0.07808811959087333 5.990166085564236e-13 BR00117020 ELANE final orf D19 A549 48 4715 Hole +0.08055501170372076 9.804861677902187e-13 BR00117021 PTK2B final orf J18 A549 48 4355 Hole +0.07405778621643926 1.4529988894010379e-12 BR00117020 PTK2B final orf J18 A549 48 5080 Hole +0.07158671586715867 1.6943837202566685e-12 BR00117020 FGF1 final orf F22 A549 48 5420 Hole +0.07465137923034909 9.01407906873751e-12 BR00117020 AKR1B1 final orf L10 A549 48 4680 Hole +0.07077432880591766 1.2986296258281097e-11 BR00117021 OPRM1 final orf A09 A549 48 5135 Hole +0.073125 1.3971929058854027e-11 BR00117021 RNASE1 final orf G17 A549 48 4800 Hole +0.07951070336391437 3.1102243811170335e-11 BR00117020 CDK4 final orf B21 A549 48 3920 Hole +0.06851872401497329 4.766546098639008e-11 BR00117021 ICAM1 final orf I08 A549 48 5200 Hole +0.07534883720930233 4.8951910711504794e-11 BR00117021 CCR1 final orf F24 A549 48 4300 Hole +0.07538591760691815 4.960778468758748e-11 BR00117021 KCNH7 final orf A22 A549 48 4280 Hole +0.06418918918918919 5.027776237043323e-11 BR00117020 SSTR2 final orf D02 A549 48 5920 Hole +0.0671115347950429 1.083535960584403e-10 BR00117020 HDAC3 final orf N06 A549 48 5245 Hole +0.07193761306409818 1.2575658260811857e-10 BR00117021 MAPK8 final orf I14 A549 48 4520 Hole +0.07593462006607546 1.3374017593860683e-10 BR00117021 IMPDH1 final orf N20 A549 48 4050 Hole +0.06508178844056707 1.4015820502734768e-10 BR00117020 EDNRB final orf M08 A549 48 5500 Hole +0.06647454370797311 2.0219270429540154e-10 BR00117020 AURKB final orf H10 A549 48 5205 Hole +0.07063588068812801 2.121325976710063e-10 BR00117020 PLK1 final orf L11 A549 48 4580 Hole +0.07025862068965517 2.2217182272286347e-10 BR00117020 CACNG1 final orf A16 A549 48 4640 Hole +0.06854166666666667 3.16912080688702e-10 BR00117020 AKR1C1 final orf A24 A549 48 4800 Hole +0.06526849666981728 4.0584623089791376e-10 BR00117021 PRKCB final orf K14 A549 48 5220 Hole +0.06812957157784744 4.4542997729499873e-10 BR00117020 PAK1 final orf L12 A549 48 4785 Hole +0.06646586345381526 5.500196364876463e-10 BR00117020 TGFBR1 final orf I23 A549 48 4980 Hole +0.06867599569429494 6.02830380574206e-10 BR00117021 PLA2G1B final orf E06 A549 48 4645 Hole +0.060711188204683436 1.1691426522065861e-09 BR00117021 HRH4 final orf O05 A549 48 5765 Hole +0.06400842664708607 1.4410318079651267e-09 BR00117020 ADA final orf P03 A549 48 5130 Hole +0.06482370857224584 1.655301065888953e-09 BR00117020 RET final orf E03 A549 48 4960 Hole +0.06521509142153535 1.865671480195272e-09 BR00117020 GHSR final orf A17 A549 48 4865 Hole +0.0672251903991772 2.333235411416975e-09 BR00117020 PNLIP final orf J09 A549 48 4530 Hole +0.06550299252766283 3.1107200190118735e-09 BR00117021 ERBB2 final orf I20 A549 48 4705 Hole +0.0653767179127205 3.981797131655219e-09 BR00117020 KCNJ1 final orf M03 A549 48 4660 Hole +0.05801050731477043 5.003936954529742e-09 BR00117021 BTK final orf N01 A549 48 5855 Hole +0.06172399855148901 5.5043418289919614e-09 BR00117021 LPAR1 final orf B05 A549 48 5160 Hole +0.06604648842777334 6.09015715185569e-09 BR00117020 PPAT final orf F11 A549 48 4475 Hole +0.06821350408871175 6.940096059549949e-09 BR00117020 DYRK1B final orf M12 A549 48 4170 Hole +0.06237141384697408 7.382942654494273e-09 BR00117021 P3H1 final orf P24 A549 48 4970 Hole +0.06024853561845655 8.087083819003082e-09 BR00117021 FLT3 final orf K13 A549 48 5300 Hole +0.06192073957624534 8.320285038351383e-09 BR00117021 MET final orf C03 A549 48 5015 Hole +0.06609092080541376 8.821960445444853e-09 BR00117021 KCNN4 final orf A06 A549 48 4390 Hole +0.05888451269143995 1.155237947491154e-08 BR00117020 SCNN1G final orf A04 A549 48 5450 Hole +0.06258377585969617 1.2484468226535964e-08 BR00117020 TNF final orf C18 A549 48 4815 Hole +0.061387463115523205 1.2927149531924531e-08 BR00117020 PTGIS final orf H13 A549 48 4990 Hole +0.06735308478783611 1.4963003823401056e-08 BR00117021 ASIC1 final orf L21 A549 48 4105 Hole +0.06575059765228736 1.70561867348794e-08 BR00117021 GABRB2 final orf C19 A549 48 4285 Hole +0.06278918214402085 2.0294391200011642e-08 BR00117021 KRAS final orf F08 A549 48 4650 Hole +0.05590227561234561 2.1933022974450405e-08 BR00117021 HSP90AB1 final orf P01 A549 48 5855 Hole +0.0634565321035811 2.2438697109826506e-08 BR00117021 PARP3 final orf H21 A549 48 4525 Hole +0.0578268876611418 2.5798380016978146e-08 BR00117020 SIRT2 final orf G02 A549 48 5430 Hole +0.05884615384615385 2.998859797087695e-08 BR00117020 MAPK8 final orf I13 A549 48 5200 Hole +0.06278814489571899 3.1473967925691485e-08 BR00117021 PRKCE final orf L14 A549 48 4555 Hole +0.06475841992446217 3.290158542948583e-08 BR00117020 MMP2 final orf J15 A549 48 4255 Hole +0.056807021996574454 3.2907136421658694e-08 BR00117021 EZH2 final orf D03 A549 48 5535 Hole +0.0630750273822563 4.666743581669387e-08 BR00117021 EDNRB final orf K11 A549 48 4400 Hole +0.057659372026641294 5.1295077282243433e-08 BR00117020 LPAR1 final orf B05 A549 48 5255 Hole +0.05546764140408384 5.8078755913756576e-08 BR00117020 GRIN2A final orf A05 A549 48 5630 Hole +0.05960290238749824 5.818748711625991e-08 BR00117021 TGM2 final orf B07 A549 48 4865 Hole +0.0590562785701796 7.00254788854533e-08 BR00117021 IL1B final orf G08 A549 48 4900 Hole +0.05714105219211268 7.079062845352794e-08 BR00117020 CHEK2 final orf F07 A549 48 5225 Hole +0.06 7.428739858879127e-08 BR00117020 GRIN2A final orf I24 A549 48 4750 Hole +0.056195630946845945 8.381707847337181e-08 BR00117020 PDPK1 final orf D06 A549 48 5365 Hole +0.05826991407609667 8.549404713459484e-08 BR00117020 HSP90AA1 final orf C14 A549 48 4985 Hole +0.05571785440015646 9.582172692718026e-08 BR00117020 KCNN1 final orf A01 A549 48 5410 Hole +0.062216700146849165 1.004281369130169e-07 BR00117020 PTK2B final orf N19 A549 48 4325 Hole +0.06274712152509766 1.1851011121559671e-07 BR00117020 GPR119 final orf N23 A549 48 4215 Hole +0.05356018840076402 1.268674334823755e-07 BR00117020 TUBB3 final orf K05 A549 48 5760 Hole +0.05966662563367987 1.26896863914746e-07 BR00117021 MMP2 final orf F06 A549 48 4630 Hole +0.054288820395971334 1.4843507395079887e-07 BR00117021 SSTR2 final orf J01 A549 48 5540 Hole +0.05688286813301432 1.5677831962515915e-07 BR00117020 TNNC1 final orf G07 A549 48 5030 Hole +0.05504291176003449 1.9020135644470595e-07 BR00117020 MMP2 final orf F06 A549 48 5310 Hole +0.05694164989939638 1.9930381010943594e-07 BR00117020 FFAR2 final orf P06 A549 48 4970 Hole +0.061878589459136345 2.8334708822828155e-07 BR00117021 OPRL1 final orf A23 A549 48 4110 Hole +0.06356997952831167 2.86756804811496e-07 BR00117021 MET final orf C08 A549 48 3890 Hole +0.058458124556014096 2.914172634104587e-07 BR00117021 PRKCE final orf J19 A549 48 4585 Hole +0.05183178206490305 4.992603550925593e-07 BR00117020 CCND1 final orf P16 A549 48 5630 Hole +0.052398211479689066 5.194349607896131e-07 BR00117021 IGF1R final orf H05 A549 48 5490 Hole +0.05581990042420631 6.42652857155511e-07 BR00117020 SLCO2B1 final orf A02 A549 48 4790 Hole +0.05724852926384717 6.503017357359395e-07 BR00117020 ATM final orf E11 A549 48 4535 Hole +0.05510971319938818 6.651634959856236e-07 BR00117021 CDK2 final orf L03 A549 48 4890 Hole +0.05559707114756354 6.9384362488475e-07 BR00117021 TUBB3 final orf G06 A549 48 4790 Hole +0.06370294732653345 6.947514350249729e-07 BR00117021 DYRK1B final orf M12 A549 48 3650 Hole +0.049608064824901855 9.175020359700305e-07 BR00117020 KCNQ2 final orf K01 A549 48 5910 Hole +0.0567787903484725 9.516067796204559e-07 BR00117021 CTSG final orf F19 A549 48 4500 Hole +0.053217145029819606 1.0067430668775704e-06 BR00117020 CA14 final orf J14 A549 48 5105 Hole +0.04996337977024652 1.2277517225414638e-06 BR00117021 ADA final orf P03 A549 48 5700 Hole +0.05489348511396981 1.287118422489307e-06 BR00117020 CASP3 final orf J10 A549 48 4705 Hole +0.05358948432760364 1.3526656549806479e-06 BR00117020 OPRL1 final orf A23 A549 48 4945 Hole +0.05353535353535353 1.3722333207660703e-06 BR00117021 PTGIR final orf C07 A549 48 4950 Hole 0.13539325842696628 4.585696753107976e-43 BR00117021 HPGDS final orf O24 A549 48 5340 Interphase 0.10234986945169713 1.3209965804806773e-26 BR00117021 S1PR1 final orf L01 A549 48 5745 Interphase 0.11149144254278728 1.5073018400367916e-22 BR00117021 CHRM3 final orf A10 A549 48 4090 Interphase @@ -1279,6 +12709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.0837473173802865 8.428465892378695e-18 BR00117021 NTRK1 final orf P02 A549 48 5690 Interphase 0.09984085377270174 1.8096706393366332e-17 BR00117020 CDK4 final orf B21 A549 48 3920 Interphase 0.09730392156862745 3.161362509126004e-17 BR00117021 FPR1 final orf D21 A549 48 4080 Interphase +0.10361552755744655 3.8976724943525687e-17 BR00117021 GHSR final orf C24 A549 48 3565 Interphase +0.08897616462196406 5.213666401120662e-17 BR00117020 TNF final orf C18 A549 48 4815 Interphase +0.09096691384291868 5.666604724597434e-17 BR00117020 PRKCE final orf J19 A549 48 4580 Interphase +0.08871388470103983 7.220166577595458e-17 BR00117021 TUBB3 final orf G06 A549 48 4790 Interphase +0.0848975572528948 1.5812769261562318e-16 BR00117020 VEGFA final orf B09 A549 48 5130 Interphase +0.08770833333333333 1.7606310355010965e-16 BR00117020 AKR1C1 final orf A24 A549 48 4800 Interphase +0.0833364774290914 3.8715587104235403e-16 BR00117021 ICAM1 final orf I08 A549 48 5200 Interphase +0.08957577554766583 1.664387106009078e-15 BR00117021 SLC7A11 final orf G24 A549 48 4315 Interphase +0.07897674057862104 1.7838697290669874e-15 BR00117021 SSTR2 final orf J01 A549 48 5540 Interphase +0.08213588684452837 2.5037095006859736e-15 BR00117020 CHRM3 final orf A10 A549 48 5060 Interphase +0.08395833333333333 3.897708165754739e-15 BR00117021 RNASE1 final orf G17 A549 48 4800 Interphase +0.0769670953546513 6.172907802639636e-15 BR00117020 CCND1 final orf P16 A549 48 5630 Interphase +0.07942857142857143 7.992138927374956e-15 BR00117021 KCNH7 final orf O07 A549 48 5250 Interphase +0.08480147795195588 1.1724623024172497e-14 BR00117020 ATM final orf E11 A549 48 4535 Interphase +0.07812359878436759 1.5420901985137934e-14 BR00117021 FLT3 final orf K13 A549 48 5300 Interphase +0.08446535756447135 4.548811121485322e-14 BR00117021 KCNN4 final orf A06 A549 48 4390 Interphase +0.08067365821735016 8.320509396624129e-14 BR00117021 ATM final orf C04 A549 48 4715 Interphase +0.07851648333788405 9.410627047096853e-14 BR00117020 RET final orf E03 A549 48 4960 Interphase +0.07576923076923077 2.112611674004342e-13 BR00117020 MAPK8 final orf I13 A549 48 5200 Interphase +0.08017241379310344 2.1680047942472525e-13 BR00117020 CACNG1 final orf A16 A549 48 4640 Interphase +0.0808155543015852 3.6294152851797626e-13 BR00117020 CACNB4 final orf A18 A549 48 4470 Interphase +0.08805294523752467 4.145042622147962e-13 BR00117021 UGT1A9 final orf E24 A549 48 3745 Interphase +0.06950958097146355 7.128669770493998e-13 BR00117020 TUBB4B final orf E07 A549 48 5910 Interphase +0.08044932883910604 9.077250710129853e-13 BR00117020 CCR1 final orf F24 A549 48 4380 Interphase +0.0760608229458817 1.4927128358337093e-12 BR00117021 FGF1 final orf F22 A549 48 4815 Interphase +0.07526173191556301 1.729636207249807e-12 BR00117021 CDK2 final orf L03 A549 48 4890 Interphase +0.07879065576975233 2.302369633186521e-12 BR00117021 SLC29A1 final orf L20 A549 48 4405 Interphase +0.06938842692721368 3.0096806071899247e-12 BR00117021 UGT1A9 final orf O09 A549 48 5630 Interphase +0.07882426358865664 3.462536325748576e-12 BR00117020 PORCN final orf N11 A549 48 4335 Interphase +0.07104029990627929 3.973835782019707e-12 BR00117021 CATSPER4 final orf P07 A549 48 5335 Interphase +0.07230320699708455 4.08169255987282e-12 BR00117020 PRKCE final orf L14 A549 48 5145 Interphase +0.06758493101565945 4.276487866636539e-12 BR00117021 BTK final orf N01 A549 48 5855 Interphase +0.06519582817815396 4.306436376512423e-12 BR00117021 HCK final orf O01 A549 48 6310 Interphase +0.0759956942949408 4.369734166797584e-12 BR00117021 PLA2G1B final orf E06 A549 48 4645 Interphase +0.06951171152928053 5.497451250031684e-12 BR00117020 FLT3 final orf K13 A549 48 5495 Interphase +0.07404343329886245 6.020037605506434e-12 BR00117020 CDK2 final orf J04 A549 48 4835 Interphase +0.0732371733218115 8.698753314580272e-12 BR00117021 HDAC6 final orf K03 A549 48 4865 Interphase +0.0729207580134426 8.963776966935985e-12 BR00117021 RPL3 final orf G09 A549 48 4895 Interphase +0.07262593927510502 9.784561052511033e-12 BR00117020 KCNN4 final orf A06 A549 48 4910 Interphase +0.07164146565673737 1.0286811337685704e-11 BR00117020 KCNN4 final orf O17 A549 48 5040 Interphase +0.07935077774023601 1.1418131332865514e-11 BR00117021 TNF final orf C18 A549 48 4095 Interphase +0.07486157253599114 2.0087127046334633e-11 BR00117021 S100B final orf M20 A549 48 4515 Interphase +0.07235515305398833 2.1529756583069914e-11 BR00117020 HDAC6 final orf E20 A549 48 4810 Interphase +0.07156887234698041 2.362232942875856e-11 BR00117021 IL1B final orf G08 A549 48 4900 Interphase +0.07370461246328817 2.7096551179243342e-11 BR00117020 KCNK1 final orf C22 A549 48 4580 Interphase +0.06876690354951225 4.279481105028337e-11 BR00117021 PAK1 final orf L09 A549 48 5175 Interphase +0.08122319262812311 4.3274183053159693e-11 BR00117021 CACNB4 final orf A18 A549 48 3705 Interphase +0.06687386835569137 4.783804382509736e-11 BR00117021 KCNN4 final orf O17 A549 48 5450 Interphase +0.066286565259015 5.234481153301556e-11 BR00117021 ATM final orf E11 A549 48 5530 Interphase +0.06646973713519708 5.924119275671101e-11 BR00117020 CATSPER4 final orf P07 A549 48 5470 Interphase +0.06927710843373494 8.200798342860698e-11 BR00117020 CYP1A2 final orf F21 A549 48 4980 Interphase +0.06848434549233576 1.3541293602579171e-10 BR00117020 HSP90AA1 final orf C14 A549 48 4985 Interphase +0.06731328806983511 1.413242022284615e-10 BR00117020 F10 final orf C09 A549 48 5155 Interphase +0.07822266680059245 1.4371929375286536e-10 BR00117021 P2RY12 final orf B24 A549 48 3805 Interphase +0.07028753993610223 1.6610497347048634e-10 BR00117021 BRAF final orf C05 A549 48 4695 Interphase +0.06506770392040609 2.1157563957151235e-10 BR00117020 CACNG1 final orf E23 A549 48 5410 Interphase +0.06712809318355266 2.7101696020379695e-10 BR00117021 MET final orf C03 A549 48 5015 Interphase +0.08099106472608716 3.0675245167664217e-10 BR00117021 AKR1C1 final orf A24 A549 48 3435 Interphase +0.06392324440429269 3.410106285913959e-10 BR00117021 CCND1 final orf P16 A549 48 5480 Interphase +0.06967463922029404 3.4378479095831946e-10 BR00117021 CDK7 final orf K06 A549 48 4610 Interphase +0.06538707234784033 3.553106403630234e-10 BR00117021 MAPK14 final orf G15 A549 48 5230 Interphase +0.06856907081942631 4.5964343121597877e-10 BR00117021 ERBB2 final orf I20 A549 48 4705 Interphase +0.0706795289360404 6.259191117100024e-10 BR00117021 KCNJ1 final orf M03 A549 48 4365 Interphase +0.068967737294098 8.153757473852619e-10 BR00117021 PARP3 final orf H21 A549 48 4525 Interphase +0.06256306862133666 9.456795234757248e-10 BR00117021 ADA final orf P04 A549 48 5470 Interphase +0.06416906820365034 9.716829353065778e-10 BR00117020 AURKB final orf H10 A549 48 5205 Interphase +0.06575250750475398 1.0483464541633317e-09 BR00117020 RPL3 final orf G09 A549 48 4920 Interphase +0.06133333333333333 1.2776351144393173e-09 BR00117021 CSK final orf P05 A549 48 5625 Interphase +0.06719424859438586 1.390993602816848e-09 BR00117021 KRAS final orf F08 A549 48 4650 Interphase +0.06182094003086 1.5326635683523854e-09 BR00117021 SSTR2 final orf D02 A549 48 5480 Interphase +0.0709099261912185 1.5826121355512033e-09 BR00117021 GRIN2A final orf I24 A549 48 4155 Interphase +0.0652611172698743 2.4835683351287698e-09 BR00117020 SLCO2B1 final orf A02 A549 48 4790 Interphase +0.06666666666666667 3.1171972002713676e-09 BR00117021 CYP2A6 final orf A20 A549 48 4560 Interphase +0.06246929051510794 3.478293077497271e-09 BR00117020 IGF1R final orf H05 A549 48 5160 Interphase +0.06203163335132158 3.9151490246307356e-09 BR00117020 EZH2 final orf D03 A549 48 5195 Interphase +0.06507175424155223 4.512177659269372e-09 BR00117021 OPRM1 final orf A08 A549 48 4690 Interphase +0.062171153082209364 5.503298045192125e-09 BR00117021 SCNN1G final orf O03 A549 48 5090 Interphase +0.059518158377394506 6.499742698661857e-09 BR00117021 IGF1R final orf H05 A549 48 5490 Interphase +0.06679872451965845 8.056995050997517e-09 BR00117020 ITGB2 final orf B12 A549 48 4305 Interphase +0.06517063511465311 8.428673599023031e-09 BR00117021 RPL23A final orf G16 A549 48 4520 Interphase +0.06686955406960175 8.898607190255473e-09 BR00117021 GABRB2 final orf C19 A549 48 4285 Interphase +0.06435829632955811 1.0399691896777923e-08 BR00117021 PRKCE final orf J19 A549 48 4585 Interphase +0.05787021945714703 1.0671175723860827e-08 BR00117021 AKR1C1 final orf I01 A549 48 5675 Interphase +0.057872358817268786 1.2492027482107199e-08 BR00117020 ATP5F1D final orf G14 A549 48 5610 Interphase +0.06611988811198131 1.6151440320975533e-08 BR00117021 DYRK1B final orf G13 A549 48 4245 Interphase +0.06106118010839464 1.662614290762497e-08 BR00117021 P3H1 final orf P24 A549 48 4970 Interphase +0.05993627453190105 1.7138034913670666e-08 BR00117021 LPAR1 final orf B05 A549 48 5160 Interphase +0.06470013846122052 1.7858050092078394e-08 BR00117021 HIF1A final orf A12 A549 48 4400 Interphase +0.06281879089528136 1.8526485751441076e-08 BR00117020 KCNJ1 final orf M03 A549 48 4660 Interphase +0.05975521065767508 1.9309883810393953e-08 BR00117020 KCNH7 final orf O07 A549 48 5160 Interphase 0.23356783806409712 1.0574065974428276e-87 BR00117021 DYRK1B final orf M12 A549 48 3650 Large 0.19582417582417583 1.1021121861889154e-76 BR00117020 DYRK1B final orf G13 A549 48 4550 Large 0.1857160455025322 2.581387771444866e-63 BR00117020 DYRK1B final orf M12 A549 48 4170 Large @@ -1289,6 +12809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.10929425387984962 6.061508665385275e-30 BR00117021 AKR1C1 final orf I01 A549 48 5675 Large 0.11342552486110259 3.131951353524036e-29 BR00117020 HTR2C final orf G21 A549 48 5135 Large 0.09700279328076039 4.091050189078705e-28 BR00117020 HSP90AB1 final orf P01 A549 48 6750 Large +0.10069009593581743 7.137473014120756e-28 BR00117021 P2RY12 final orf B01 A549 48 6220 Large +0.10737110875324982 5.866762097046654e-26 BR00117020 PTK2B final orf J18 A549 48 5080 Large +0.10380952380952381 4.879026926464366e-25 BR00117021 KCNH7 final orf O07 A549 48 5250 Large +0.09603216513971663 1.8366215159373223e-24 BR00117021 KDR final orf O02 A549 48 5985 Large +0.09538729329852046 3.689087214855001e-23 BR00117021 S1PR1 final orf L01 A549 48 5745 Large +0.08907760340794808 1.1522336634758591e-20 BR00117021 HSP90AB1 final orf P01 A549 48 5855 Large +0.10199799891803496 3.356460589725585e-20 BR00117021 PTK2B final orf J18 A549 48 4355 Large +0.0923780487804878 6.332535130408006e-20 BR00117020 CACNA2D3 final orf P19 A549 48 5250 Large +0.08763373710743855 1.7236089605452943e-19 BR00117021 NTRK1 final orf P02 A549 48 5690 Large +0.09254204874335355 2.048420747765047e-19 BR00117020 ITGB2 final orf P21 A549 48 5085 Large +0.08433261142786555 7.789417352358016e-19 BR00117021 OPRL1 final orf O16 A549 48 5940 Large +0.08584467086848459 1.1891681456015842e-18 BR00117021 KCNQ2 final orf K01 A549 48 5670 Large +0.08340728047897351 1.9842483850684743e-18 BR00117021 CACNA2D3 final orf L02 A549 48 5940 Large +0.08620460063008396 3.957755771690861e-18 BR00117021 ADA final orf P04 A549 48 5470 Large +0.08938351974060223 8.564211524699736e-18 BR00117020 VEGFA final orf P18 A549 48 4985 Large +0.08478239434179985 1.3896601915009463e-17 BR00117021 CCND1 final orf P16 A549 48 5480 Large +0.08331264814246986 3.253502398726319e-17 BR00117021 GPR119 final orf N02 A549 48 5550 Large +0.0822358401369827 9.958787574941143e-17 BR00117021 CCR1 final orf P17 A549 48 5535 Large +0.0841103710751665 1.373434991488508e-16 BR00117020 LPAR1 final orf B05 A549 48 5255 Large +0.09037541070863998 2.3520132289567647e-16 BR00117020 CACNB4 final orf A18 A549 48 4470 Large +0.08443497832985264 2.83633092677329e-16 BR00117020 CA14 final orf J14 A549 48 5105 Large +0.08079270315906416 3.7733834498168757e-16 BR00117021 CACNB4 final orf M01 A549 48 5525 Large +0.07940404422739009 4.147939151358137e-16 BR00117021 ADA final orf P03 A549 48 5700 Large +0.08068519715578538 4.193621056999803e-16 BR00117021 ATM final orf E11 A549 48 5530 Large +0.08082737159647978 1.6449967758968227e-15 BR00117020 S100B final orf I09 A549 48 5295 Large +0.07736339982653946 2.0064110677440542e-15 BR00117021 HRH4 final orf O05 A549 48 5765 Large +0.07602280443761102 2.6584184851176667e-15 BR00117020 TUBB4B final orf E07 A549 48 5910 Large +0.08257441118686387 6.1239637686484836e-15 BR00117021 CA5A final orf B02 A549 48 4890 Large +0.07599171628526855 1.1448374707981886e-14 BR00117021 RET final orf K10 A549 48 5660 Large +0.07378451865519421 1.232558451093402e-14 BR00117021 FOXM1 final orf J02 A549 48 5990 Large +0.07693532930174152 1.2521366144351504e-14 BR00117020 EDNRB final orf M08 A549 48 5500 Large +0.08002970867287464 1.7695398953756423e-14 BR00117021 RPL3 final orf K12 A549 48 5035 Large +0.0745986656151724 2.0644188511647333e-14 BR00117020 TUBB3 final orf K05 A549 48 5760 Large +0.07358085750698609 3.139545836563332e-14 BR00117021 PIK3CG final orf I03 A549 48 5850 Large +0.07378628931473956 5.038958317150188e-14 BR00117020 GLRA3 final orf K04 A549 48 5735 Large +0.07436652982761105 9.854104093723112e-14 BR00117020 SCNN1G final orf O03 A549 48 5515 Large +0.07201811495924598 1.1098573253397386e-13 BR00117020 USP1 final orf G11 A549 48 5870 Large +0.08591969280109836 1.299257889782223e-13 BR00117021 TNF final orf C18 A549 48 4095 Large +0.08144895718990121 1.4608505861789314e-13 BR00117021 PRKCE final orf L14 A549 48 4555 Large +0.07634923508889507 2.2470631901237946e-13 BR00117021 SCNN1G final orf O03 A549 48 5090 Large +0.07152726270758772 3.6081790889136256e-13 BR00117021 GLRA3 final orf K04 A549 48 5720 Large +0.0843520782396088 4.455980144206594e-13 BR00117021 CHRM3 final orf A10 A549 48 4090 Large +0.07359550561797752 5.366999464704117e-13 BR00117021 HPGDS final orf O24 A549 48 5340 Large +0.0675642363546632 6.343186123745656e-13 BR00117020 COMT final orf P09 A549 48 6295 Large +0.07063343358342748 1.2692766590693184e-12 BR00117021 NTRK1 final orf D01 A549 48 5615 Large +0.09009282653232407 1.3588838062031723e-12 BR00117021 AKR1C1 final orf A24 A549 48 3435 Large +0.07457445914397508 1.3644974770921135e-12 BR00117021 PTGIS final orf H13 A549 48 5010 Large +0.0819176823292766 1.788085358043873e-12 BR00117021 OPRL1 final orf A23 A549 48 4110 Large +0.07501656742943781 2.1117605157485452e-12 BR00117021 CDK2 final orf L03 A549 48 4890 Large +0.07444006362437575 2.712479298351835e-12 BR00117021 KCNN1 final orf A01 A549 48 4910 Large +0.07379515283352202 3.858474789882704e-12 BR00117021 SCNN1G final orf A04 A549 48 4930 Large +0.07015769062182917 4.122545736258094e-12 BR00117021 ADH1C final orf O04 A549 48 5445 Large +0.07360970677451972 4.5208596042377525e-12 BR00117020 OPRL1 final orf A23 A549 48 4945 Large +0.0748171368861024 4.560332048754402e-12 BR00117020 PAK1 final orf L12 A549 48 4785 Large +0.0733931850642726 5.954206488535486e-12 BR00117020 PDE7A final orf J11 A549 48 4900 Large +0.07176796958803264 9.958688760529713e-12 BR00117021 HPGDS final orf O21 A549 48 5035 Large +0.07124243654886257 1.3747881740891256e-11 BR00117020 KCNN4 final orf O17 A549 48 5040 Large +0.07084675142557535 1.5759013177629923e-11 BR00117020 SSTR2 final orf J01 A549 48 5080 Large +0.07002965698617873 1.7185622648981223e-11 BR00117021 AGER final orf H09 A549 48 5175 Large +0.06819047501817314 2.2241344599718422e-11 BR00117020 CACNG1 final orf E23 A549 48 5410 Large +0.06880301602262016 2.4375745555395553e-11 BR00117020 CSK final orf P05 A549 48 5305 Large +0.0681940331949266 3.3486199944840756e-11 BR00117020 TGFBR1 final orf O14 A549 48 5310 Large +0.06673209268312713 3.408294230709122e-11 BR00117021 SSTR2 final orf J01 A549 48 5540 Large +0.06729737522710379 3.5719854310608776e-11 BR00117021 TUBB3 final orf K05 A549 48 5445 Large +0.07569923165302313 5.689282412968875e-11 BR00117021 VEGFA final orf B09 A549 48 4220 Large +0.06799969009653785 5.902660975405343e-11 BR00117021 HBB final orf M11 A549 48 5230 Large +0.06852589641434263 1.1387820774693091e-10 BR00117020 CYP3A4 final orf K22 A549 48 5020 Large +0.07071352502662406 1.2523342454300334e-10 BR00117021 BRAF final orf C05 A549 48 4695 Large +0.07183758978451715 1.6855014800465975e-10 BR00117020 PPAT final orf F11 A549 48 4475 Large +0.0690075804345322 2.0958632979962404e-10 BR00117020 TNF final orf C18 A549 48 4815 Large +0.06291776241542395 2.1419123306263713e-10 BR00117021 PTPN2 final orf O15 A549 48 5775 Large +0.0625613186292586 2.727678516907908e-10 BR00117020 GPR119 final orf N02 A549 48 5785 Large +0.06328413931185757 3.4878551541115485e-10 BR00117020 CDC25A final orf M04 A549 48 5600 Large +0.06335743487224318 3.9048039669661173e-10 BR00117021 ALDH2 final orf P13 A549 48 5545 Large +0.06910656620021528 4.5744805985938483e-10 BR00117021 PLA2G1B final orf E06 A549 48 4645 Large +0.07152987677284353 4.860757945990162e-10 BR00117020 CTSG final orf J12 A549 48 4300 Large +0.0635938667402586 5.033639138748428e-10 BR00117021 KCNN4 final orf O17 A549 48 5450 Large +0.06377880184331797 5.147882155358418e-10 BR00117020 GJB4 final orf P08 A549 48 5425 Large +0.060731548542791336 5.694461501573757e-10 BR00117020 CCR1 final orf P17 A549 48 5950 Large +0.06796383696693244 5.742140844357749e-10 BR00117020 AGER final orf H18 A549 48 4745 Large +0.06517943743937925 6.081811340352398e-10 BR00117020 RET final orf K10 A549 48 5155 Large +0.06434307063891687 7.276291770993316e-10 BR00117021 TUBB4B final orf E07 A549 48 5235 Large +0.07213669293762484 7.873495529488718e-10 BR00117021 LCK final orf B18 A549 48 4140 Large +0.06902899330171614 8.073007673362181e-10 BR00117021 MAPK8 final orf I14 A549 48 4520 Large +0.06279926335174954 9.89794452225848e-10 BR00117020 RNASE1 final orf I18 A549 48 5430 Large +0.06342857142857143 1.3264797858591593e-09 BR00117021 NAMPT final orf L06 A549 48 5250 Large +0.07389033942558747 1.630870944100227e-09 BR00117020 ANXA1 final orf D23 A549 48 3830 Large +0.07174129899605561 1.6482311590521662e-09 BR00117021 IMPDH1 final orf N20 A549 48 4050 Large +0.06641852406209049 1.8736828781975946e-09 BR00117021 OPRM1 final orf A08 A549 48 4690 Large +0.062230552952202436 2.1052906819705506e-09 BR00117021 CATSPER4 final orf P07 A549 48 5335 Large 0.16728170975722378 4.863557329458443e-45 BR00117021 DYRK1B final orf M12 A549 48 3650 Metaphase 0.14175332801449672 5.9409328618046315e-37 BR00117020 DYRK1B final orf M12 A549 48 4170 Metaphase 0.1221978021978022 5.291688474965008e-30 BR00117020 DYRK1B final orf G13 A549 48 4550 Metaphase @@ -1299,6 +12909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.09047114289658385 6.231844826749334e-18 BR00117021 KCNN1 final orf A01 A549 48 4910 Metaphase 0.07611355013420835 2.4975157596534144e-16 BR00117021 HCK final orf O01 A549 48 6310 Metaphase 0.078486339839378 1.0368321071505357e-15 BR00117021 NTRK1 final orf P02 A549 48 5690 Metaphase +0.06950682032799392 1.7022110053104459e-13 BR00117021 P2RY12 final orf B01 A549 48 6220 Metaphase +0.07637827517983391 3.4844543786774155e-13 BR00117021 PTGIS final orf H13 A549 48 5010 Metaphase +0.07145023640772027 4.711043450996519e-13 BR00117021 AKR1C1 final orf I01 A549 48 5675 Metaphase +0.07564771817453964 6.82283160729255e-13 BR00117021 LYN final orf M05 A549 48 5000 Metaphase +0.07395255837166827 1.9947279604398242e-12 BR00117021 HPGDS final orf O21 A549 48 5035 Metaphase +0.0772315924937511 3.926698782550105e-12 BR00117020 CHRM3 final orf A11 A549 48 4510 Metaphase +0.06451769604643828 4.6470821482949586e-11 BR00117021 BTK final orf N01 A549 48 5855 Metaphase +0.06529516994633273 8.793549151856389e-11 BR00117020 S1PR4 final orf K18 A549 48 5590 Metaphase +0.06288538929064005 1.1749429116082134e-10 BR00117021 OPRL1 final orf O16 A549 48 5940 Metaphase +0.06964710121516172 2.306910557549853e-10 BR00117020 SLC7A11 final orf G24 A549 48 4705 Metaphase +0.06763199087743386 3.503594840635404e-10 BR00117020 CATSPER4 final orf D24 A549 48 4895 Metaphase +0.06457142857142857 6.148056053371703e-10 BR00117021 NAMPT final orf L06 A549 48 5250 Metaphase +0.06587268516194245 1.1206223645539307e-09 BR00117021 CA5A final orf B02 A549 48 4890 Metaphase +0.059549624687239365 1.1576481880617035e-09 BR00117021 RET final orf E03 A549 48 5995 Metaphase +0.061219673848117634 1.877320810195556e-09 BR00117021 ATM final orf E11 A549 48 5530 Metaphase +0.06868249661211626 1.9440606555063935e-09 BR00117020 CCR1 final orf F24 A549 48 4380 Metaphase +0.055204227786832614 2.116295558635689e-09 BR00117020 HSP90AB1 final orf P01 A549 48 6750 Metaphase +0.062420353372711776 2.1176508574382573e-09 BR00117021 CACNA2D3 final orf P19 A549 48 5280 Metaphase +0.06309813060941141 2.170756056900531e-09 BR00117021 LPAR1 final orf B05 A549 48 5160 Metaphase +0.0626321893353424 2.259004422587216e-09 BR00117021 TUBB4B final orf E07 A549 48 5235 Metaphase +0.06128992084713735 2.4309851058599813e-09 BR00117021 TUBB3 final orf K05 A549 48 5445 Metaphase +0.05887760731748377 2.7654737727239248e-09 BR00117021 HSP90AB1 final orf P01 A549 48 5855 Metaphase +0.06582484799648378 2.940603259907319e-09 BR00117021 AVPR1A final orf H22 A549 48 4675 Metaphase +0.06109022556390977 4.718972934046687e-09 BR00117020 ABL1 final orf C01 A549 48 5320 Metaphase +0.06048970614103223 4.862182020770361e-09 BR00117021 LCK final orf H01 A549 48 5405 Metaphase +0.0628601293446954 5.4015933291502555e-09 BR00117020 HSP90AA1 final orf C14 A549 48 4985 Metaphase +0.05902222222222222 6.1189282266415796e-09 BR00117021 CSK final orf P05 A549 48 5625 Metaphase +0.05857058932187586 1.0661539014479828e-08 BR00117021 CCR1 final orf P17 A549 48 5535 Metaphase +0.05742640052042063 1.380039640805173e-08 BR00117021 KCNQ2 final orf K01 A549 48 5670 Metaphase +0.05948026948989413 2.0654411541058997e-08 BR00117021 FPR1 final orf L04 A549 48 5195 Metaphase +0.057478771617704726 2.155699251723391e-08 BR00117021 EZH2 final orf D03 A549 48 5535 Metaphase +0.0595538774773846 3.112963166065141e-08 BR00117020 CHRM3 final orf A10 A549 48 5060 Metaphase +0.056376518235088664 4.199144799809826e-08 BR00117021 ALDH2 final orf P13 A549 48 5545 Metaphase +0.05759325230024663 4.328793735271201e-08 BR00117021 TNNC1 final orf G07 A549 48 5290 Metaphase +0.0632409359076688 5.037009353013874e-08 BR00117021 PDE7A final orf F20 A549 48 4355 Metaphase +0.05615570869808158 8.231036291952142e-08 BR00117021 CSK final orf B04 A549 48 5370 Metaphase +0.05910949513858264 8.660008031893712e-08 BR00117020 HTR3A final orf J23 A549 48 4830 Metaphase +0.06188919630649206 8.735578842689459e-08 BR00117020 MME final orf K20 A549 48 4405 Metaphase +0.060240011647012336 8.815004553190952e-08 BR00117021 KRAS final orf F08 A549 48 4650 Metaphase +0.05445074271365134 8.873911593554648e-08 BR00117021 ADA final orf P03 A549 48 5700 Metaphase +0.06399831979937265 8.956565873100055e-08 BR00117021 ASIC1 final orf L21 A549 48 4105 Metaphase +0.05944020174072746 9.423806711012448e-08 BR00117020 ADH1C final orf M23 A549 48 4755 Metaphase +0.05716443647534954 1.2774650286753652e-07 BR00117021 HTR2C final orf M06 A549 48 5050 Metaphase +0.05550899782387914 1.5452935344617127e-07 BR00117020 S100B final orf I09 A549 48 5295 Metaphase +0.05854224073530279 1.5564250232978493e-07 BR00117020 MAPK14 final orf G22 A549 48 4755 Metaphase +0.05732373332148147 1.6853884763002824e-07 BR00117021 SCNN1G final orf A04 A549 48 4930 Metaphase +0.06475195822454308 2.1035307626569006e-07 BR00117020 ANXA1 final orf D23 A549 48 3830 Metaphase +0.05365835852059515 2.142368396164875e-07 BR00117021 GPR119 final orf N02 A549 48 5550 Metaphase +0.05214782892862822 2.2247662949207322e-07 BR00117021 KCNMA1 final orf G01 A549 48 5860 Metaphase +0.057989417989417986 2.49654846594384e-07 BR00117021 CLK1 final orf D08 A549 48 4725 Metaphase +0.05311184864947586 2.642034043072465e-07 BR00117020 CDC25A final orf M04 A549 48 5600 Metaphase +0.057794329257807905 2.89394250563124e-07 BR00117020 MET final orf C08 A549 48 4700 Metaphase +0.05515285308747239 3.1122254440333413e-07 BR00117020 HTR2C final orf G21 A549 48 5135 Metaphase +0.05986300111273314 4.444510089626112e-07 BR00117020 S100B final orf M20 A549 48 4255 Metaphase +0.050751258095793 6.552308012132552e-07 BR00117021 PDPK1 final orf D06 A549 48 5775 Metaphase +0.05586919605513052 7.27805221827627e-07 BR00117021 AKT1 final orf J16 A549 48 4720 Metaphase +0.05065274151436031 7.895318188028424e-07 BR00117021 S1PR1 final orf L01 A549 48 5745 Metaphase +0.05286638091064349 8.236638656463721e-07 BR00117021 SLCO2B1 final orf O13 A549 48 5240 Metaphase +0.056 9.986387336585017e-07 BR00117020 FFAR4 final orf I16 A549 48 4625 Metaphase +0.05515789473684211 1.052823920785788e-06 BR00117020 CYP2A6 final orf A20 A549 48 4750 Metaphase +0.05374145055341752 1.065173557273032e-06 BR00117021 CYP1A2 final orf N12 A549 48 4980 Metaphase +0.054159901414666235 1.0689405832059997e-06 BR00117021 IL1B final orf G08 A549 48 4900 Metaphase +0.05316279170777412 1.1045897715235568e-06 BR00117020 SSTR2 final orf J01 A549 48 5080 Metaphase +0.050064364257095345 1.1234448450106835e-06 BR00117021 GLRA3 final orf K04 A549 48 5720 Metaphase +0.054654696240864754 1.1453789702901645e-06 BR00117021 TUBB3 final orf G06 A549 48 4790 Metaphase +0.05407026293361952 1.1947421364982e-06 BR00117020 ATP5F1D final orf C21 A549 48 4875 Metaphase +0.052693437806072475 1.3895032559375702e-06 BR00117021 SIRT2 final orf A07 A549 48 5105 Metaphase +0.05268389662027833 1.7200427360168761e-06 BR00117021 BAX final orf K17 A549 48 5030 Metaphase +0.055320927453531475 1.7631244918420517e-06 BR00117021 RGS4 final orf D20 A549 48 4535 Metaphase +0.052816603604485576 1.7661162527089943e-06 BR00117020 EDNRB final orf K11 A549 48 4975 Metaphase +0.05318265612383259 2.0213701035097e-06 BR00117020 CSF1R final orf D14 A549 48 4860 Metaphase +0.05927502328431453 2.139663825412535e-06 BR00117021 AURKB final orf L19 A549 48 3890 Metaphase +0.055883728525703835 2.2249503098724502e-06 BR00117020 CA5A final orf B23 A549 48 4375 Metaphase +0.048882210634510766 2.574720050657624e-06 BR00117021 KCNQ2 final orf K02 A549 48 5650 Metaphase +0.05047619047619047 3.0896470300337493e-06 BR00117021 KCNH7 final orf O07 A549 48 5250 Metaphase +0.0531418701472596 3.137244702916982e-06 BR00117021 ATP5F1D final orf C21 A549 48 4715 Metaphase +0.059814478222735494 3.2953415808883843e-06 BR00117021 CACNB4 final orf A18 A549 48 3705 Metaphase +0.061914009214871904 3.439881544459371e-06 BR00117021 AKR1C1 final orf A24 A549 48 3435 Metaphase +0.05227272727272727 3.5930319198166317e-06 BR00117020 CHRM2 final orf B03 A549 48 4840 Metaphase +0.057393483709273184 3.89609371300281e-06 BR00117020 BRAF final orf I10 A549 48 3990 Metaphase +0.05615174310320103 4.024732200385989e-06 BR00117021 MME final orf K20 A549 48 4145 Metaphase +0.048816029143897995 4.145211446059601e-06 BR00117020 ICAM1 final orf I15 A549 48 5490 Metaphase +0.05203806439325089 4.273060856498333e-06 BR00117021 ADRA2B final orf N18 A549 48 4795 Metaphase +0.05257510729613734 5.069284376954413e-06 BR00117021 PIK3CG final orf G18 A549 48 4660 Metaphase +0.047758171697107575 5.115245404646729e-06 BR00117021 PAK4 final orf G10 A549 48 5620 Metaphase +0.052370689655172414 5.91877564995086e-06 BR00117020 CACNG1 final orf A16 A549 48 4640 Metaphase +0.04647349086162933 7.184212529209148e-06 BR00117020 GPR119 final orf N02 A549 48 5785 Metaphase +0.0516573672075 7.310571367636451e-06 BR00117020 KCNJ1 final orf M03 A549 48 4660 Metaphase +0.05371083511377149 8.088100227628402e-06 BR00117021 TBXAS1 final orf J24 A549 48 4290 Metaphase +0.054939503760253534 8.268883943667421e-06 BR00117020 P2RY12 final orf B24 A549 48 4085 Metaphase 0.11928838951310862 1.6781154814406812e-33 BR00117021 HPGDS final orf O24 A549 48 5340 MetaphaseAlignment 0.1184390973694053 4.154304892016774e-23 BR00117021 CACNB4 final orf A18 A549 48 3705 MetaphaseAlignment 0.103550603706683 2.5631544306396036e-21 BR00117020 CACNB4 final orf A18 A549 48 4470 MetaphaseAlignment @@ -1309,6 +13009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.08426186878384716 5.500244848264539e-15 BR00117020 GHSR final orf C24 A549 48 4705 MetaphaseAlignment 0.08168537448559843 1.1871239587822888e-14 BR00117021 RPL3 final orf G09 A549 48 4895 MetaphaseAlignment 0.08229985384928538 2.102922270384491e-14 BR00117021 AKR1B1 final orf L17 A549 48 4735 MetaphaseAlignment +0.0849005229703212 3.3962975810941313e-14 BR00117020 CCR1 final orf F24 A549 48 4380 MetaphaseAlignment +0.07733333333333334 4.498005392364301e-14 BR00117021 KCNH7 final orf O07 A549 48 5250 MetaphaseAlignment +0.08488372093023255 6.773933378139146e-14 BR00117021 CCR1 final orf F24 A549 48 4300 MetaphaseAlignment +0.0778871096877502 1.2077478684841105e-13 BR00117021 LYN final orf M05 A549 48 5000 MetaphaseAlignment +0.08358485329081562 3.0429022572912784e-13 BR00117020 GPR119 final orf N23 A549 48 4215 MetaphaseAlignment +0.07240638656384056 6.502409052614549e-13 BR00117020 CATSPER4 final orf P07 A549 48 5470 MetaphaseAlignment +0.08168669705874806 8.376743181018357e-13 BR00117020 S100B final orf M20 A549 48 4255 MetaphaseAlignment +0.07070994775784428 8.421779917589454e-13 BR00117021 NTRK1 final orf P02 A549 48 5690 MetaphaseAlignment +0.08274712482006745 1.2616464115044814e-12 BR00117020 P2RY12 final orf B24 A549 48 4085 MetaphaseAlignment +0.0769005154870961 1.550537746688725e-12 BR00117021 ERBB2 final orf I20 A549 48 4705 MetaphaseAlignment +0.07541666666666667 2.718955927674932e-12 BR00117020 AKR1C1 final orf A24 A549 48 4800 MetaphaseAlignment +0.0729064039408867 3.771660073326008e-12 BR00117020 LCK final orf B18 A549 48 5075 MetaphaseAlignment +0.06728184736204577 4.305576318209647e-12 BR00117020 TUBB4B final orf E07 A549 48 5910 MetaphaseAlignment +0.07198059085424584 4.707478334555341e-12 BR00117020 OPRM1 final orf A08 A549 48 5160 MetaphaseAlignment +0.07069003719628136 1.2875073688418064e-11 BR00117020 VEGFA final orf B09 A549 48 5130 MetaphaseAlignment +0.06893897820208461 2.89029511080101e-11 BR00117021 TUBB4B final orf E07 A549 48 5235 MetaphaseAlignment +0.07034293935099765 5.3560559868473533e-11 BR00117020 KCNN4 final orf A06 A549 48 4910 MetaphaseAlignment +0.0619064742691364 5.588311825115031e-11 BR00117021 HCK final orf O01 A549 48 6310 MetaphaseAlignment +0.06692531522793405 1.8491788609265346e-10 BR00117020 PTPN2 final orf O15 A549 48 5155 MetaphaseAlignment +0.06787878787878789 2.4509795449461777e-10 BR00117021 PTGIR final orf C07 A549 48 4950 MetaphaseAlignment +0.06457454398276773 2.9559812033194214e-10 BR00117020 AVPR1A final orf D07 A549 48 5400 MetaphaseAlignment +0.06304484548483164 3.68901917637903e-10 BR00117020 ATP5F1D final orf G14 A549 48 5610 MetaphaseAlignment +0.07705038341720585 3.9962291045356836e-10 BR00117021 UGT1A9 final orf E24 A549 48 3745 MetaphaseAlignment +0.06988128667729519 4.402036809728621e-10 BR00117020 ATM final orf E11 A549 48 4535 MetaphaseAlignment +0.06666666666666667 4.81370724779945e-10 BR00117020 CYP1A2 final orf F21 A549 48 4980 MetaphaseAlignment +0.06264840182648401 9.193382784933487e-10 BR00117020 RGS4 final orf D09 A549 48 5475 MetaphaseAlignment +0.06000057767765995 1.3521600497140325e-09 BR00117021 HSP90AB1 final orf P01 A549 48 5855 MetaphaseAlignment +0.06655203308687113 1.7161263381785313e-09 BR00117020 MET final orf C08 A549 48 4700 MetaphaseAlignment +0.06437633816017396 1.7939019645013513e-09 BR00117020 SLC29A1 final orf N03 A549 48 5010 MetaphaseAlignment +0.06568571591734887 1.8835938522380655e-09 BR00117020 SLCO2B1 final orf A02 A549 48 4790 MetaphaseAlignment +0.06343355965082444 1.9381260585085773e-09 BR00117020 F10 final orf C09 A549 48 5155 MetaphaseAlignment +0.06645367412140575 1.953831361073949e-09 BR00117021 BRAF final orf C05 A549 48 4695 MetaphaseAlignment +0.06172103817306147 2.57303114906718e-09 BR00117020 SIRT2 final orf A07 A549 48 5350 MetaphaseAlignment +0.06012551856185512 3.918589535252975e-09 BR00117021 ATM final orf E11 A549 48 5530 MetaphaseAlignment +0.0648421052631579 4.191809942548281e-09 BR00117020 CYP2A6 final orf A20 A549 48 4750 MetaphaseAlignment +0.06240591705096366 4.340723277968663e-09 BR00117020 CA14 final orf J14 A549 48 5105 MetaphaseAlignment +0.07133592736705577 5.959052620878532e-09 BR00117021 COMT final orf B10 A549 48 3855 MetaphaseAlignment +0.058666666666666666 7.744756125897145e-09 BR00117021 CSK final orf P05 A549 48 5625 MetaphaseAlignment +0.062487360970677454 8.143248827832151e-09 BR00117020 OPRL1 final orf A23 A549 48 4945 MetaphaseAlignment +0.0638124191935894 8.588430721946983e-09 BR00117021 ATP5F1D final orf C21 A549 48 4715 MetaphaseAlignment +0.06129614077184563 1.2853360100951369e-08 BR00117020 FFAR4 final orf C17 A549 48 5000 MetaphaseAlignment +0.07373592054672422 1.4815081510779568e-08 BR00117021 AKR1C1 final orf A24 A549 48 3435 MetaphaseAlignment +0.059865255052935516 1.6264373029678654e-08 BR00117021 FPR1 final orf L04 A549 48 5195 MetaphaseAlignment +0.06335135135135135 1.7185080926949494e-08 BR00117020 UGT1A9 final orf E24 A549 48 4625 MetaphaseAlignment +0.05877265284618511 3.5171211771809654e-08 BR00117021 CDC25A final orf M04 A549 48 5155 MetaphaseAlignment +0.058886306574836254 3.5964379813463525e-08 BR00117021 OPRM1 final orf A09 A549 48 5135 MetaphaseAlignment +0.055526544821583985 4.028083390405321e-08 BR00117021 S1PR1 final orf L01 A549 48 5745 MetaphaseAlignment +0.06559931605392542 4.100679532282117e-08 BR00117021 ASIC1 final orf L21 A549 48 4105 MetaphaseAlignment +0.05475667118733677 4.2965284026823395e-08 BR00117020 P2RY12 final orf B01 A549 48 5865 MetaphaseAlignment +0.05434578469263693 4.5328302780661786e-08 BR00117020 F10 final orf I04 A549 48 5950 MetaphaseAlignment +0.061422413793103446 4.9495962273083306e-08 BR00117020 CACNG1 final orf A16 A549 48 4640 MetaphaseAlignment +0.06232869205854688 9.279961385482195e-08 BR00117020 PORCN final orf N11 A549 48 4335 MetaphaseAlignment +0.05831313716709254 9.764737528065629e-08 BR00117020 LYN final orf C20 A549 48 4930 MetaphaseAlignment +0.05386630152911803 9.78665949000989e-08 BR00117020 PDE3A final orf O19 A549 48 5785 MetaphaseAlignment +0.053946227233304424 1.0276516868081432e-07 BR00117021 HRH4 final orf O05 A549 48 5765 MetaphaseAlignment +0.060526315789473685 1.1025215450990583e-07 BR00117021 CYP2A6 final orf A20 A549 48 4560 MetaphaseAlignment +0.05781492331552645 1.1347964121284608e-07 BR00117021 P3H1 final orf P24 A549 48 4970 MetaphaseAlignment +0.05967034601711256 1.3926293208997447e-07 BR00117021 CDK7 final orf K06 A549 48 4610 MetaphaseAlignment +0.057348272991315646 1.8363901138875764e-07 BR00117021 PDE4D final orf B22 A549 48 4905 MetaphaseAlignment +0.053034834290294715 1.9412858667573524e-07 BR00117021 GLRA3 final orf K04 A549 48 5720 MetaphaseAlignment +0.050963184199597444 2.0148535930817723e-07 BR00117020 DHH final orf G05 A549 48 6190 MetaphaseAlignment +0.054098360655737705 2.0910132604798866e-07 BR00117020 ICAM1 final orf I15 A549 48 5490 MetaphaseAlignment +0.06074626104979415 2.366853085021173e-07 BR00117021 PDE4D final orf B17 A549 48 4305 MetaphaseAlignment +0.05558794946550048 2.475491214650715e-07 BR00117020 PRKCE final orf L14 A549 48 5145 MetaphaseAlignment +0.06036008805600062 2.6901443893116736e-07 BR00117020 ANXA1 final orf N24 A549 48 4325 MetaphaseAlignment +0.05587364264560711 2.697506060607969e-07 BR00117020 UGT1A9 final orf O09 A549 48 5065 MetaphaseAlignment +0.05586202567155864 2.7076131220602654e-07 BR00117021 ADORA2A final orf O23 A549 48 5050 MetaphaseAlignment +0.05441868811171585 2.8227352158934023e-07 BR00117020 ALDH2 final orf P13 A549 48 5315 MetaphaseAlignment +0.055286129970902036 2.852482546768929e-07 BR00117020 RET final orf K10 A549 48 5155 MetaphaseAlignment +0.05132413555503424 3.051508631064984e-07 BR00117021 OPRL1 final orf O16 A549 48 5940 MetaphaseAlignment +0.056424136681810046 3.143889469909473e-07 BR00117020 PDE7A final orf J11 A549 48 4900 MetaphaseAlignment +0.05580765849734715 3.494458041424527e-07 BR00117020 EDNRB final orf K11 A549 48 4975 MetaphaseAlignment +0.057301221731965724 3.500870963601851e-07 BR00117021 CA14 final orf J14 A549 48 4720 MetaphaseAlignment +0.05487800884105028 3.9886251962048773e-07 BR00117021 CACNG1 final orf A16 A549 48 5095 MetaphaseAlignment +0.057196740445139636 4.4920221011884936e-07 BR00117020 KCNJ1 final orf M03 A549 48 4660 MetaphaseAlignment +0.05444602866876149 4.834776510866264e-07 BR00117021 USP1 final orf G11 A549 48 5130 MetaphaseAlignment +0.05322436458353049 6.708086543887732e-07 BR00117021 SLCO2B1 final orf O13 A549 48 5240 MetaphaseAlignment +0.058859909092650514 6.728829763085482e-07 BR00117021 HDAC6 final orf E20 A549 48 4275 MetaphaseAlignment +0.05239852398523985 6.852540740827889e-07 BR00117020 FGF1 final orf F22 A549 48 5420 MetaphaseAlignment +0.05201842735982651 7.084136895842788e-07 BR00117020 FOXM1 final orf P15 A549 48 5470 MetaphaseAlignment +0.053986879605788005 7.38515957435797e-07 BR00117021 ADORA2A final orf O18 A549 48 5065 MetaphaseAlignment +0.051949856740755446 7.76259170701154e-07 BR00117020 SCNN1G final orf A04 A549 48 5450 MetaphaseAlignment +0.05227185900075876 9.345811454924316e-07 BR00117021 SLC29A1 final orf N03 A549 48 5310 MetaphaseAlignment +0.054314724249364774 1.1123972136959414e-06 BR00117020 CSF1R final orf D14 A549 48 4860 MetaphaseAlignment +0.04943403635926532 1.1884362876134085e-06 BR00117021 BTK final orf N01 A549 48 5855 MetaphaseAlignment +0.057045454545454545 1.2021388599713635e-06 BR00117020 PDE4D final orf B22 A549 48 4400 MetaphaseAlignment +0.05133595536236223 1.2372465255964712e-06 BR00117021 LCK final orf H01 A549 48 5405 MetaphaseAlignment +0.05308927762203603 1.2493497253816287e-06 BR00117021 MAPK8 final orf I13 A549 48 5050 MetaphaseAlignment +0.05507354190299264 1.2507957924421166e-06 BR00117021 PPARD final orf M07 A549 48 4680 MetaphaseAlignment +0.05489773950484392 1.655665680782407e-06 BR00117021 PLA2G1B final orf E06 A549 48 4645 MetaphaseAlignment 0.15493717550689437 1.2298220031542273e-38 BR00117021 DYRK1B final orf M12 A549 48 3650 OutOfFocus 0.1483255576917609 5.74275576891235e-36 BR00117021 CACNB4 final orf A18 A549 48 3705 OutOfFocus 0.11021118510908808 8.16407781811784e-34 BR00117021 HCK final orf O01 A549 48 6310 OutOfFocus @@ -1319,6 +13109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.1211030835896771 2.9919575607038814e-23 BR00117021 GHSR final orf C24 A549 48 3565 OutOfFocus 0.0906875543951262 5.6880631305507066e-21 BR00117021 S1PR1 final orf L01 A549 48 5745 OutOfFocus 0.08859460069782295 1.8044700024867223e-20 BR00117021 HSP90AB1 final orf P01 A549 48 5855 OutOfFocus +0.09557398612352273 6.571106495710372e-20 BR00117021 CDK2 final orf L03 A549 48 4890 OutOfFocus +0.10289128274912475 1.1814686530541368e-19 BR00117020 DYRK1B final orf M12 A549 48 4170 OutOfFocus +0.09161904761904761 1.3714327649141156e-19 BR00117021 KCNH7 final orf O07 A549 48 5250 OutOfFocus +0.08875119512560802 2.1113851330408248e-19 BR00117021 CACNB4 final orf M01 A549 48 5525 OutOfFocus +0.0943153163544919 2.190681994185275e-19 BR00117021 RPL3 final orf G09 A549 48 4895 OutOfFocus +0.09964525023394394 2.318850459534101e-19 BR00117020 CCR1 final orf F24 A549 48 4380 OutOfFocus +0.08567717521661383 2.5109803761877295e-19 BR00117020 TUBB4B final orf E07 A549 48 5910 OutOfFocus +0.10268948655256724 3.4620364600075785e-19 BR00117021 CHRM3 final orf A10 A549 48 4090 OutOfFocus +0.09545718207828348 7.863944821736969e-19 BR00117021 MMP2 final orf F06 A549 48 4630 OutOfFocus +0.09429494079655544 2.1848260812753242e-18 BR00117021 PLA2G1B final orf E06 A549 48 4645 OutOfFocus +0.09208333333333334 3.996374682263982e-18 BR00117021 RNASE1 final orf G17 A549 48 4800 OutOfFocus +0.08750314288888499 7.32448875580492e-18 BR00117021 MAPK14 final orf G15 A549 48 5230 OutOfFocus +0.09288793103448276 7.779891851766801e-18 BR00117020 CACNG1 final orf A16 A549 48 4640 OutOfFocus +0.0766803312424886 9.966676568907443e-18 BR00117020 HSP90AB1 final orf P01 A549 48 6750 OutOfFocus +0.10045845555347521 1.1026748796869093e-17 BR00117020 CDK4 final orf B21 A549 48 3920 OutOfFocus +0.08391111111111112 1.2068003435726792e-17 BR00117021 CSK final orf P05 A549 48 5625 OutOfFocus +0.09094736842105264 1.644835200276506e-17 BR00117020 CYP2A6 final orf A20 A549 48 4750 OutOfFocus +0.08807184350419026 2.1030163025830886e-17 BR00117021 MET final orf C03 A549 48 5015 OutOfFocus +0.08979166666666667 2.970590132561623e-17 BR00117020 AKR1C1 final orf A24 A549 48 4800 OutOfFocus +0.08114854103994561 9.965347342050382e-17 BR00117021 AKR1C1 final orf I01 A549 48 5675 OutOfFocus +0.08839190628328009 2.243128563077625e-16 BR00117021 BRAF final orf C05 A549 48 4695 OutOfFocus +0.08519559481011252 3.2276327833545536e-16 BR00117020 HSP90AA1 final orf C14 A549 48 4985 OutOfFocus +0.09389099935746564 3.4377391906545275e-16 BR00117021 ASIC1 final orf L21 A549 48 4105 OutOfFocus +0.07840416305290547 7.865704629989111e-16 BR00117021 HRH4 final orf O05 A549 48 5765 OutOfFocus +0.08096414646373087 4.673805696485793e-15 BR00117020 VEGFA final orf B09 A549 48 5130 OutOfFocus +0.07955559667765101 4.972517752220751e-15 BR00117021 FLT3 final orf K13 A549 48 5300 OutOfFocus +0.07686694541497222 1.1733154865487598e-14 BR00117021 ATM final orf E11 A549 48 5530 OutOfFocus +0.0843956043956044 1.626480742628437e-14 BR00117020 DYRK1B final orf G13 A549 48 4550 OutOfFocus +0.08053220605635085 1.90827974309809e-14 BR00117020 RET final orf E03 A549 48 4960 OutOfFocus +0.07591377694470477 8.649919350665303e-14 BR00117021 CATSPER4 final orf P07 A549 48 5335 OutOfFocus +0.08676470588235294 8.844154827355289e-14 BR00117021 FPR1 final orf D21 A549 48 4080 OutOfFocus +0.0768046198267565 9.554888849377762e-14 BR00117021 FPR1 final orf L04 A549 48 5195 OutOfFocus +0.07954545454545454 9.729218020063356e-14 BR00117020 CHRM2 final orf B03 A549 48 4840 OutOfFocus +0.08183807439824946 9.884828914530515e-14 BR00117021 TNNC1 final orf M18 A549 48 4570 OutOfFocus +0.0716226525029764 1.5630806320913285e-13 BR00117021 ABL1 final orf C01 A549 48 5870 OutOfFocus +0.07205014817345064 2.456557166136947e-13 BR00117021 ADA final orf P03 A549 48 5700 OutOfFocus +0.08323253120576503 9.066207849090306e-13 BR00117020 P2RY12 final orf B24 A549 48 4085 OutOfFocus +0.07561659636309125 1.1818973563796373e-12 BR00117020 PDE7A final orf J11 A549 48 4900 OutOfFocus +0.07087974148522162 1.4235846671402225e-12 BR00117021 SSTR2 final orf J01 A549 48 5540 OutOfFocus +0.07366375121477162 1.466711325029924e-12 BR00117020 PRKCE final orf L14 A549 48 5145 OutOfFocus +0.06805671392827356 1.71236489172805e-12 BR00117021 RET final orf E03 A549 48 5995 OutOfFocus +0.07317910598021671 1.749617570415314e-12 BR00117020 KCNH7 final orf O07 A549 48 5160 OutOfFocus +0.07524045992095083 1.983009959317761e-12 BR00117021 HDAC6 final orf K03 A549 48 4865 OutOfFocus +0.08943746579160969 2.1556738161609273e-12 BR00117021 AKR1C1 final orf A24 A549 48 3435 OutOfFocus +0.07623394013528588 2.483332327955548e-12 BR00117020 GHSR final orf C24 A549 48 4705 OutOfFocus +0.07352609603550994 3.7756088410339265e-12 BR00117020 EDNRB final orf K11 A549 48 4975 OutOfFocus +0.07987484031545243 5.575807804576417e-12 BR00117021 GRIN2A final orf I24 A549 48 4155 OutOfFocus +0.07316905317923848 7.669486267631279e-12 BR00117020 CATSPER4 final orf D24 A549 48 4895 OutOfFocus +0.07841719850050036 7.815577304518209e-12 BR00117020 S100B final orf M20 A549 48 4255 OutOfFocus +0.06704936809607681 9.418140256385775e-12 BR00117020 PDE3A final orf O19 A549 48 5785 OutOfFocus +0.07435179235635357 9.437962829689868e-12 BR00117020 MET final orf C08 A549 48 4700 OutOfFocus +0.07208835341365462 1.1297626667523476e-11 BR00117020 CYP1A2 final orf F21 A549 48 4980 OutOfFocus +0.08222283662400716 1.224942384939573e-11 BR00117021 P2RY12 final orf B24 A549 48 3805 OutOfFocus +0.06543614083163056 1.699838288014027e-11 BR00117021 CACNA2D3 final orf L02 A549 48 5940 OutOfFocus +0.08035782157968457 2.1560621042380635e-11 BR00117021 MET final orf C08 A549 48 3890 OutOfFocus +0.06721877556676607 3.177179444388575e-11 BR00117021 CCND1 final orf P16 A549 48 5480 OutOfFocus +0.06577281708331857 3.3390562751478544e-11 BR00117021 GLRA3 final orf K04 A549 48 5720 OutOfFocus +0.07375206695099036 3.471724443832329e-11 BR00117020 ATM final orf E11 A549 48 4535 OutOfFocus +0.06987770977755112 3.631584868324096e-11 BR00117020 KCNN4 final orf O17 A549 48 5040 OutOfFocus +0.07253951552947065 3.8176071889557654e-11 BR00117020 AKR1B1 final orf L10 A549 48 4680 OutOfFocus +0.0706025502415501 4.105716804546246e-11 BR00117020 KCNN4 final orf A06 A549 48 4910 OutOfFocus +0.07023627831942673 6.049541601912161e-11 BR00117021 CA5A final orf B02 A549 48 4890 OutOfFocus +0.07374803115627765 6.870950510788889e-11 BR00117020 HIF1A final orf A12 A549 48 4410 OutOfFocus +0.07465116279069768 7.683285992737985e-11 BR00117021 CATSPER4 final orf D24 A549 48 4300 OutOfFocus +0.07077491180138483 1.0912279057891639e-10 BR00117021 ERBB2 final orf I20 A549 48 4705 OutOfFocus +0.0651300059748213 1.28547308534253e-10 BR00117020 GPR55 final orf F13 A549 48 5505 OutOfFocus +0.06445730044882668 1.3503472233144747e-10 BR00117020 ATP5F1D final orf G14 A549 48 5610 OutOfFocus +0.06130529257038834 1.359724846687966e-10 BR00117021 P2RY12 final orf B01 A549 48 6220 OutOfFocus +0.06765873927392994 1.4666079587578136e-10 BR00117021 SCNN1G final orf O03 A549 48 5090 OutOfFocus +0.07091891891891892 1.5536009573556886e-10 BR00117020 UGT1A9 final orf E24 A549 48 4625 OutOfFocus +0.06641419150096693 2.3088479175102795e-10 BR00117020 OPRM1 final orf A08 A549 48 5160 OutOfFocus +0.06413720650142452 2.661908525448094e-10 BR00117020 SCNN1G final orf O03 A549 48 5515 OutOfFocus +0.06428449067320484 2.8567180431363777e-10 BR00117021 ADA final orf P04 A549 48 5470 OutOfFocus +0.07065337763012182 3.203626738212897e-10 BR00117021 S100B final orf M20 A549 48 4515 OutOfFocus +0.06169761818605297 3.6959728941300976e-10 BR00117020 USP1 final orf G11 A549 48 5870 OutOfFocus +0.05987497751887175 4.144206830237843e-10 BR00117020 DHH final orf G05 A549 48 6190 OutOfFocus +0.06169952225729118 5.151925937473507e-10 BR00117021 PTPN2 final orf O15 A549 48 5775 OutOfFocus +0.0762786992343067 5.970693697761206e-10 BR00117021 UGT1A9 final orf E24 A549 48 3745 OutOfFocus +0.060577728366351724 6.458420499832484e-10 BR00117021 OPRL1 final orf O16 A549 48 5940 OutOfFocus +0.0671338655947641 7.321906359047456e-10 BR00117020 HDAC6 final orf E20 A549 48 4810 OutOfFocus +0.06575698335017122 8.279170138438063e-10 BR00117020 PAK4 final orf M19 A549 48 4975 OutOfFocus +0.06781115879828326 9.742750409175459e-10 BR00117021 FFAR2 final orf B15 A549 48 4660 OutOfFocus +0.06468631279206637 1.2029692440333717e-09 BR00117021 ALDH2 final orf P14 A549 48 5055 OutOfFocus +0.06314028881945581 1.2601165636789707e-09 BR00117021 CHRM2 final orf B03 A549 48 5300 OutOfFocus +0.06565952807782874 1.4272538253227828e-09 BR00117020 CSF1R final orf D14 A549 48 4860 OutOfFocus +0.06976744186046512 1.6025677351882288e-09 BR00117021 CCR1 final orf F24 A549 48 4300 OutOfFocus +0.06343355965082444 1.9381260585085773e-09 BR00117020 F10 final orf C09 A549 48 5155 OutOfFocus +0.06603174603174604 2.229317347073719e-09 BR00117021 CLK1 final orf D08 A549 48 4725 OutOfFocus +0.0643686941861384 2.4422678752517762e-09 BR00117020 LYN final orf C20 A549 48 4930 OutOfFocus +0.058501045704278574 2.8225421354362225e-09 BR00117020 CACNA2D3 final orf L02 A549 48 5940 OutOfFocus 0.12451157180964953 1.5130094726087661e-24 BR00117021 GHSR final orf C24 A549 48 3565 Polylobed 0.10105058210777136 6.476012276275699e-23 BR00117020 CHRM3 final orf A10 A549 48 5060 Polylobed 0.10126315789473685 1.298775611033456e-21 BR00117020 CYP2A6 final orf A20 A549 48 4750 Polylobed @@ -1329,6 +13209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.095625 1.6288001003709357e-19 BR00117020 AKR1C1 final orf A24 A549 48 4800 Polylobed 0.0994856742783283 1.2060744198867179e-18 BR00117021 VEGFA final orf B09 A549 48 4220 Polylobed 0.10601119429917519 1.3664488556230325e-18 BR00117021 CACNB4 final orf A18 A549 48 3705 Polylobed +0.08906543201119443 3.761841263563972e-18 BR00117021 OPRM1 final orf A09 A549 48 5135 Polylobed +0.08832027364642837 3.722838767383939e-17 BR00117021 SCNN1G final orf A04 A549 48 4930 Polylobed +0.07996705186284028 6.61298524020523e-17 BR00117020 TUBB4B final orf E07 A549 48 5910 Polylobed +0.08947368421052632 2.676205835180125e-16 BR00117021 CYP2A6 final orf A20 A549 48 4560 Polylobed +0.08812171786065284 5.882935616745262e-16 BR00117020 PRKCE final orf J19 A549 48 4580 Polylobed +0.08071796183230509 6.720076338806694e-16 BR00117020 SCNN1G final orf A04 A549 48 5450 Polylobed +0.08591898537054407 7.790836785918613e-16 BR00117021 TUBB3 final orf G06 A549 48 4790 Polylobed +0.08580365191959789 1.656138600619368e-15 BR00117020 GHSR final orf C24 A549 48 4705 Polylobed +0.08956879189853725 1.7108821948963079e-15 BR00117021 SLC7A11 final orf G24 A549 48 4315 Polylobed +0.0838618060875577 1.815730100614285e-15 BR00117021 PDE4D final orf B22 A549 48 4905 Polylobed +0.087063728374014 3.240603690401505e-15 BR00117020 CACNB4 final orf A18 A549 48 4470 Polylobed +0.09387023765268143 4.548059089509541e-15 BR00117021 P2RY12 final orf B24 A549 48 3805 Polylobed +0.08997555012224939 8.005783361974048e-15 BR00117021 CHRM3 final orf A10 A549 48 4090 Polylobed +0.08771608331806242 8.762048097269433e-15 BR00117021 KCNH7 final orf A22 A549 48 4280 Polylobed +0.07934034899498281 1.485804954541242e-14 BR00117021 LPAR1 final orf B05 A549 48 5160 Polylobed +0.08149560320991776 2.4530170722590097e-14 BR00117020 TNF final orf C18 A549 48 4815 Polylobed +0.08792254140368393 2.9801431544226156e-14 BR00117021 OPRL1 final orf A23 A549 48 4110 Polylobed +0.08213358475363422 4.721755726334983e-14 BR00117021 MMP2 final orf F06 A549 48 4630 Polylobed +0.08186740431078111 5.0383304387634486e-14 BR00117021 KRAS final orf F08 A549 48 4650 Polylobed +0.0840361721231066 6.263626948886958e-14 BR00117021 KCNN4 final orf A06 A549 48 4390 Polylobed +0.08418604651162791 1.1262124134764661e-13 BR00117021 CCR1 final orf F24 A549 48 4300 Polylobed +0.08194905869324474 1.3164535025227142e-13 BR00117021 S100B final orf M20 A549 48 4515 Polylobed +0.08293607262499318 1.6732455881249623e-13 BR00117021 PTK2B final orf J18 A549 48 4355 Polylobed +0.07875490855583953 1.85822106316776e-13 BR00117021 GABRB2 final orf C06 A549 48 4830 Polylobed +0.07736654447260127 3.0745111944116525e-13 BR00117021 HBB final orf C10 A549 48 4910 Polylobed +0.07878571640007294 3.815907526106553e-13 BR00117021 ERBB2 final orf I20 A549 48 4705 Polylobed +0.06795608795227864 5.896539161998692e-13 BR00117021 P2RY12 final orf B01 A549 48 6220 Polylobed +0.07864852471947219 8.512116364173853e-13 BR00117021 PRKCE final orf J19 A549 48 4585 Polylobed +0.09064905707696401 1.0248196131346748e-12 BR00117021 AKR1C1 final orf A24 A549 48 3435 Polylobed +0.07535353535353535 1.2134733608813558e-12 BR00117021 CYP3A4 final orf K22 A549 48 4950 Polylobed +0.07833698030634573 1.2889820107236211e-12 BR00117021 TNNC1 final orf M18 A549 48 4570 Polylobed +0.07356878689651057 1.6769125409349467e-12 BR00117020 VEGFA final orf B09 A549 48 5130 Polylobed +0.08009581700078551 2.489643210896682e-12 BR00117020 S100B final orf M20 A549 48 4255 Polylobed +0.07277359051916497 2.52123113532388e-12 BR00117020 OPRM1 final orf A08 A549 48 5160 Polylobed +0.0736232524591933 2.623431562735452e-12 BR00117021 FGF1 final orf F03 A549 48 5020 Polylobed +0.07650798761749819 3.5417040563466976e-12 BR00117021 CDK7 final orf K06 A549 48 4610 Polylobed +0.0729064039408867 3.771660073326008e-12 BR00117020 LCK final orf B18 A549 48 5075 Polylobed +0.0840322709481588 5.5540104489307216e-12 BR00117021 UGT1A9 final orf E24 A549 48 3745 Polylobed +0.07381805667882689 5.636691353207771e-12 BR00117021 TGM2 final orf B07 A549 48 4865 Polylobed +0.07589228963966166 8.878322210415668e-12 BR00117021 MAPK8 final orf I14 A549 48 4520 Polylobed +0.07239635995955511 1.0872219580684105e-11 BR00117020 OPRL1 final orf A23 A549 48 4945 Polylobed +0.06928838951310862 1.4430119091877414e-11 BR00117021 HPGDS final orf O24 A549 48 5340 Polylobed +0.07510690626025014 1.4672999915772925e-11 BR00117021 PARP3 final orf H21 A549 48 4525 Polylobed +0.07544096135316349 1.4939531537382906e-11 BR00117021 S1PR2 final orf B06 A549 48 4475 Polylobed +0.06958174904942965 1.710010470538148e-11 BR00117020 KDR final orf A21 A549 48 5260 Polylobed +0.0714859437751004 1.7392069106924206e-11 BR00117020 CYP1A2 final orf F21 A549 48 4980 Polylobed +0.06983511154219205 2.3700533079449263e-11 BR00117020 RET final orf K10 A549 48 5155 Polylobed +0.06949579800849276 2.384333145635303e-11 BR00117021 ICAM1 final orf I08 A549 48 5200 Polylobed +0.07073841843169378 3.08377669461989e-11 BR00117020 RET final orf E03 A549 48 4960 Polylobed +0.0705050505050505 4.0446107305326247e-11 BR00117021 CHRM3 final orf A11 A549 48 4950 Polylobed +0.06938159269135734 4.197928236508746e-11 BR00117021 CACNG1 final orf A16 A549 48 5095 Polylobed +0.07511627906976744 5.691567390746748e-11 BR00117021 CATSPER4 final orf D24 A549 48 4300 Polylobed +0.07118202304134955 8.424597221456969e-11 BR00117020 MET final orf C08 A549 48 4700 Polylobed +0.06909693768303304 8.851069391251938e-11 BR00117020 HSP90AA1 final orf C14 A549 48 4985 Polylobed +0.06654980158104074 2.2979333494104933e-10 BR00117020 KCNH7 final orf O07 A549 48 5160 Polylobed +0.06522961574507967 2.7321765943156736e-10 BR00117021 PLK1 final orf L11 A549 48 5335 Polylobed +0.07047200878155872 2.948247518211226e-10 BR00117021 PRKCE final orf L14 A549 48 4555 Polylobed +0.0661568704348989 3.0044741013155074e-10 BR00117020 IGF1R final orf H05 A549 48 5160 Polylobed +0.06998020672971189 3.9566776993465395e-10 BR00117021 CA5A final orf B23 A549 48 4550 Polylobed +0.07513314529610575 5.498053519460128e-10 BR00117021 MET final orf C08 A549 48 3890 Polylobed +0.06778947368421052 6.529571654858711e-10 BR00117020 GRIN2A final orf I24 A549 48 4750 Polylobed +0.06439216178761299 7.442182837753074e-10 BR00117021 PRKCB final orf K14 A549 48 5220 Polylobed +0.06523039860950629 8.796229936658654e-10 BR00117021 MAPK8 final orf I13 A549 48 5050 Polylobed +0.0685344891457361 1.2779684560146954e-09 BR00117021 CTSG final orf F19 A549 48 4500 Polylobed +0.07319816305727184 1.364873431402534e-09 BR00117020 CDK4 final orf B21 A549 48 3920 Polylobed +0.06699144933810461 1.411529067012051e-09 BR00117020 AKR1B1 final orf L10 A549 48 4680 Polylobed +0.06394557823129252 1.4419628310354467e-09 BR00117020 PRKCE final orf L14 A549 48 5145 Polylobed +0.06716899892357374 1.5623003252113721e-09 BR00117021 PLA2G1B final orf E06 A549 48 4645 Polylobed +0.06645502645502646 1.7097743799645597e-09 BR00117021 KCNK1 final orf C22 A549 48 4725 Polylobed +0.07111652446633727 1.9293425488412257e-09 BR00117020 P2RY12 final orf B24 A549 48 4085 Polylobed +0.06114310584068847 2.1865874612573715e-09 BR00117021 IGF1R final orf H05 A549 48 5490 Polylobed +0.06143911439114391 2.5758712537770995e-09 BR00117020 FGF1 final orf F22 A549 48 5420 Polylobed +0.06625165012467608 4.425770729830285e-09 BR00117021 RPL23A final orf G16 A549 48 4520 Polylobed +0.06530172413793103 5.0431986544520206e-09 BR00117020 CACNG1 final orf A16 A549 48 4640 Polylobed +0.06455026455026455 5.567659287808724e-09 BR00117021 CLK1 final orf D08 A549 48 4725 Polylobed +0.06336574363156755 6.4193693328946185e-09 BR00117021 IL1B final orf E15 A549 48 4850 Polylobed +0.05923711259049552 6.942399065478838e-09 BR00117021 EZH2 final orf D03 A549 48 5535 Polylobed +0.06237424547283702 7.923146082814798e-09 BR00117020 FFAR2 final orf P06 A549 48 4970 Polylobed +0.0638805159758788 8.593309111378917e-09 BR00117021 CDK4 final orf P20 A549 48 4710 Polylobed +0.062097191747402775 1.1074336830230697e-08 BR00117021 KCNN1 final orf A01 A549 48 4910 Polylobed +0.06100691016781836 1.2876849774226315e-08 BR00117020 UGT1A9 final orf O09 A549 48 5065 Polylobed +0.05980952380952381 1.3829465368659164e-08 BR00117021 KCNH7 final orf O07 A549 48 5250 Polylobed +0.0668444562667708 1.3997299901027743e-08 BR00117021 HTR2C final orf G21 A549 48 4195 Polylobed +0.06061045623302365 1.4712397420195468e-08 BR00117021 KDR final orf A21 A549 48 5085 Polylobed +0.06541121751965126 1.7533258563374188e-08 BR00117021 CDK9 final orf N22 A549 48 4320 Polylobed +0.058453914828626656 1.856322198585216e-08 BR00117020 BAX final orf K17 A549 48 5385 Polylobed +0.060235245515458294 1.8742689184895955e-08 BR00117020 ITGB2 final orf P21 A549 48 5085 Polylobed +0.061797949128127076 1.9062748732622277e-08 BR00117021 FGF1 final orf F22 A549 48 4815 Polylobed +0.054321845183139296 2.2525748915214777e-08 BR00117020 DHH final orf G05 A549 48 6190 Polylobed +0.0584757780145613 2.2894360124585588e-08 BR00117021 FFAR4 final orf I16 A549 48 5325 Polylobed 0.1194756554307116 1.3202035980621485e-33 BR00117021 HPGDS final orf O24 A549 48 5340 Prometaphase 0.08714701885668547 3.139344621522037e-17 BR00117020 PTK2B final orf J18 A549 48 5080 Prometaphase 0.08297699898088286 2.054413358747554e-13 BR00117020 PTK2B final orf N19 A549 48 4325 Prometaphase @@ -1339,6 +13309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.07168110822328677 1.3920097968413438e-10 BR00117020 PNLIP final orf J09 A549 48 4530 Prometaphase 0.06804558755832138 1.8366056946835548e-10 BR00117021 P3H1 final orf P24 A549 48 4970 Prometaphase 0.06756720139278241 2.18435296543405e-10 BR00117020 HRH4 final orf O06 A549 48 5010 Prometaphase +0.07236886312246257 2.1928717743747206e-10 BR00117021 PTK2B final orf J18 A549 48 4355 Prometaphase +0.06453745026713945 3.12416843549885e-10 BR00117020 BAX final orf G12 A549 48 5395 Prometaphase +0.06250782932104618 7.626686242602669e-10 BR00117021 CCR1 final orf P17 A549 48 5535 Prometaphase +0.06210632239999461 1.3803320790064484e-09 BR00117021 KCNN4 final orf O17 A549 48 5450 Prometaphase +0.06236043958793323 1.5937915184224494e-09 BR00117020 PPAT final orf H14 A549 48 5365 Prometaphase +0.06053805174965495 2.1233579589150894e-09 BR00117020 ATP5F1D final orf G14 A549 48 5610 Prometaphase +0.06322802610588925 2.3899728842950234e-09 BR00117021 USP1 final orf G11 A549 48 5130 Prometaphase +0.07117794486215538 3.2782592038547518e-09 BR00117020 BRAF final orf I10 A549 48 3990 Prometaphase +0.05915004336513443 3.442584220862277e-09 BR00117021 HRH4 final orf O05 A549 48 5765 Prometaphase +0.06724350703630394 3.815136587894094e-09 BR00117021 F10 final orf C09 A549 48 4425 Prometaphase +0.06961901362692072 5.473020769704062e-09 BR00117021 IMPDH1 final orf N20 A549 48 4050 Prometaphase +0.06363988557085792 6.56936515342159e-09 BR00117020 TNF final orf C18 A549 48 4815 Prometaphase +0.058591586530517825 1.1525379770768697e-08 BR00117020 EDNRB final orf M08 A549 48 5500 Prometaphase +0.05946278727144616 1.3214234860712498e-08 BR00117021 CHRM2 final orf B03 A549 48 5300 Prometaphase +0.06904698870792125 1.5345519576677672e-08 BR00117021 HSD11B1 final orf G23 A549 48 3905 Prometaphase +0.05901334794337476 1.6450890333979556e-08 BR00117020 ALDH2 final orf P13 A549 48 5315 Prometaphase +0.05793357933579336 2.4947171958509607e-08 BR00117020 FGF1 final orf F22 A549 48 5420 Prometaphase +0.05889325654561081 3.603855195799399e-08 BR00117020 CDK9 final orf H11 A549 48 5115 Prometaphase +0.05950858192555194 3.886770353223422e-08 BR00117020 VEGFA final orf P18 A549 48 4985 Prometaphase +0.05995869085505604 4.7963242584414374e-08 BR00117021 USP1 final orf E12 A549 48 4855 Prometaphase +0.05811839948259603 6.51354414199782e-08 BR00117021 TGFBR1 final orf O14 A549 48 5085 Prometaphase +0.0565739529359109 8.326003788560816e-08 BR00117020 GUCY1B1 final orf J08 A549 48 5280 Prometaphase +0.061461222300928875 8.826838627264969e-08 BR00117020 AVPR1A final orf H22 A549 48 4470 Prometaphase +0.05422222222222222 1.305810556388715e-07 BR00117021 CSK final orf P05 A549 48 5625 Prometaphase +0.0557179282100152 1.3136758706509808e-07 BR00117020 TGFBR1 final orf O14 A549 48 5310 Prometaphase +0.05995670644421922 1.767646759943127e-07 BR00117020 CHRM3 final orf A11 A549 48 4510 Prometaphase +0.05826360222973681 1.9462462871444787e-07 BR00117020 AGER final orf H18 A549 48 4745 Prometaphase +0.05304149684851072 2.0580685729026122e-07 BR00117021 NTRK1 final orf P02 A549 48 5690 Prometaphase +0.05706165755426839 2.1300850944811756e-07 BR00117020 S1PR2 final orf B06 A549 48 4900 Prometaphase +0.05558794946550048 2.475491214650715e-07 BR00117020 PRKCE final orf L14 A549 48 5145 Prometaphase +0.05980455918963266 2.6299611717427365e-07 BR00117020 HIF1A final orf A12 A549 48 4410 Prometaphase +0.056581177730086585 2.7891155005810494e-07 BR00117020 RPL3 final orf G09 A549 48 4920 Prometaphase +0.05540431082301117 3.032873869501289e-07 BR00117020 CYP1A2 final orf N12 A549 48 5085 Prometaphase +0.05817682458903833 3.38789627700696e-07 BR00117021 CYP2A6 final orf A15 A549 48 4585 Prometaphase +0.053087557603686636 4.5551005688867253e-07 BR00117020 GJB4 final orf P08 A549 48 5425 Prometaphase +0.05578512396694215 5.714437285900113e-07 BR00117020 RPL23A final orf G16 A549 48 4840 Prometaphase +0.05712510744743761 7.036467245965547e-07 BR00117020 RPL3 final orf K12 A549 48 4535 Prometaphase +0.05671851362519768 7.314745741697232e-07 BR00117020 PLK1 final orf L11 A549 48 4580 Prometaphase +0.056716130514399235 7.314778464859091e-07 BR00117020 PRKCE final orf J19 A549 48 4580 Prometaphase +0.05401606425702811 9.730918112127945e-07 BR00117020 DHH final orf E08 A549 48 4980 Prometaphase +0.055466505188668046 1.0334385528083524e-06 BR00117021 HCK final orf O20 A549 48 4680 Prometaphase +0.05651642160974527 1.0393524661128198e-06 BR00117021 RPL23A final orf I07 A549 48 4510 Prometaphase +0.054094539848872046 1.1229096342642693e-06 BR00117020 CATSPER4 final orf D24 A549 48 4895 Prometaphase +0.05419571062658494 1.2202123856380622e-06 BR00117021 HDAC3 final orf N21 A549 48 4850 Prometaphase +0.05776058938160677 1.2765214623143694e-06 BR00117020 MMP2 final orf J15 A549 48 4255 Prometaphase +0.050770625566636446 1.333836608467364e-06 BR00117021 S1PR4 final orf M17 A549 48 5515 Prometaphase +0.05321836436944351 1.3619676672063658e-06 BR00117021 KCTD16 final orf M22 A549 48 5005 Prometaphase +0.05248373636589253 1.4109071780260385e-06 BR00117020 ADA final orf P03 A549 48 5130 Prometaphase +0.05280788177339901 1.4204255082283425e-06 BR00117020 LCK final orf B18 A549 48 5075 Prometaphase +0.05258036665436595 1.5312079357036668e-06 BR00117020 ITGB2 final orf P21 A549 48 5085 Prometaphase +0.051077177947560094 1.6188606747512377e-06 BR00117020 PPARD final orf I12 A549 48 5350 Prometaphase +0.048596785367524535 1.651553310353791e-06 BR00117020 KCNQ2 final orf K01 A549 48 5910 Prometaphase +0.05428668697805852 1.81185611500308e-06 BR00117021 OPRM1 final orf A08 A549 48 4690 Prometaphase +0.05308062146268647 1.9674290552583e-06 BR00117021 CDK2 final orf L03 A549 48 4890 Prometaphase +0.05277848335824842 2.1577437771604543e-06 BR00117020 PDE7A final orf J11 A549 48 4900 Prometaphase +0.05036274523065547 2.356475760700589e-06 BR00117021 CSK final orf B04 A549 48 5370 Prometaphase +0.05356683281218352 2.362409573894934e-06 BR00117021 AKR1B1 final orf L17 A549 48 4735 Prometaphase +0.05247876662701304 2.5518438384443427e-06 BR00117021 PDE4D final orf B22 A549 48 4905 Prometaphase +0.05287152975542273 2.654100243133101e-06 BR00117020 GPR55 final orf H16 A549 48 4830 Prometaphase +0.0541513211885596 2.6796059844686034e-06 BR00117020 HTR3A final orf H24 A549 48 4595 Prometaphase +0.051807228915662654 3.119743563054971e-06 BR00117020 CYP1A2 final orf F21 A549 48 4980 Prometaphase +0.05304386153594429 3.857133562936642e-06 BR00117021 RGS4 final orf D09 A549 48 4665 Prometaphase +0.054110393560887364 5.060732727044011e-06 BR00117020 BRD4 final orf N17 A549 48 4385 Prometaphase +0.05024959202794686 5.114791263102922e-06 BR00117020 FPR1 final orf D21 A549 48 5080 Prometaphase +0.04995140913508261 5.296523876886596e-06 BR00117020 AGER final orf H09 A549 48 5145 Prometaphase +0.05002667055353804 5.6752010734164584e-06 BR00117021 TGFBR1 final orf I23 A549 48 5080 Prometaphase +0.05057163931403282 6.2532481772592915e-06 BR00117020 DDR2 final orf M02 A549 48 4930 Prometaphase +0.05746499438528398 6.2718883424308606e-06 BR00117020 PDE7A final orf F20 A549 48 3815 Prometaphase +0.0504564318798516 7.108407846565078e-06 BR00117021 BRAF final orf I10 A549 48 4905 Prometaphase +0.046988650186628685 7.5636622627683315e-06 BR00117020 CCND1 final orf P16 A549 48 5630 Prometaphase +0.04830827067669173 8.083030927218028e-06 BR00117020 ABL1 final orf C01 A549 48 5320 Prometaphase +0.05150214592274678 8.533507695195212e-06 BR00117021 ICAM1 final orf I15 A549 48 4660 Prometaphase +0.05204675939956911 8.554842693660527e-06 BR00117021 AURKB final orf H10 A549 48 4545 Prometaphase +0.05328971313011901 9.870322582267273e-06 BR00117021 S100B final orf I09 A549 48 4275 Prometaphase +0.04681138050016343 1.0570465417112485e-05 BR00117020 SCNN1G final orf O03 A549 48 5515 Prometaphase +0.051648351648351645 1.0667786794113688e-05 BR00117020 DYRK1B final orf G13 A549 48 4550 Prometaphase +0.045464607118245785 1.0707706601866066e-05 BR00117021 KCNMA1 final orf G01 A549 48 5860 Prometaphase +0.05078703025419383 1.1070034684144148e-05 BR00117021 AVPR1A final orf H22 A549 48 4675 Prometaphase +0.04725581395348837 1.2210880547875495e-05 BR00117020 CHEK2 final orf H06 A549 48 5375 Prometaphase +0.04826609810026623 1.7312873797001965e-05 BR00117021 ALK final orf H12 A549 48 4980 Prometaphase +0.04777887462981244 1.8970962388289767e-05 BR00117020 UGT1A9 final orf O09 A549 48 5065 Prometaphase +0.04780876494023904 2.072463739791143e-05 BR00117020 CYP3A4 final orf K22 A549 48 5020 Prometaphase +0.04618234434743707 2.1102713445423208e-05 BR00117020 SIRT2 final orf A07 A549 48 5350 Prometaphase +0.0464942070258474 2.5264692370838916e-05 BR00117020 BRAF final orf C05 A549 48 5190 Prometaphase +0.04742477834788474 2.6355587192847793e-05 BR00117020 HSP90AA1 final orf C14 A549 48 4985 Prometaphase +0.04511758756863949 2.6574464762451516e-05 BR00117020 FLT3 final orf K13 A549 48 5495 Prometaphase +0.0432919455975666 2.7582679904197475e-05 BR00117021 CACNA2D3 final orf L02 A549 48 5940 Prometaphase +0.050217291807198694 2.79528512596403e-05 BR00117021 SLC29A1 final orf L20 A549 48 4405 Prometaphase +0.04666754944695616 2.9140195569989753e-05 BR00117021 PLD1 final orf L05 A549 48 5090 Prometaphase +0.04701158672871865 2.957983776301572e-05 BR00117020 SLC29A1 final orf N03 A549 48 5010 Prometaphase 0.1521800337529967 2.3131465127360523e-43 BR00117021 DYRK1B final orf G13 A549 48 4245 SmallIrregular 0.13333333333333333 8.97149728136375e-42 BR00117021 HPGDS final orf O24 A549 48 5340 SmallIrregular 0.14065934065934066 1.2005214994370178e-39 BR00117020 DYRK1B final orf G13 A549 48 4550 SmallIrregular @@ -1349,6 +13409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.10251577595353772 1.1140432380960408e-23 BR00117020 PTK2B final orf J18 A549 48 5080 SmallIrregular 0.09290573372206025 9.738967773614162e-20 BR00117020 PRKCE final orf L14 A549 48 5145 SmallIrregular 0.08881922675026123 7.714435099741477e-17 BR00117020 PAK1 final orf L12 A549 48 4785 SmallIrregular +0.08520426409180314 8.944204082442137e-17 BR00117021 LPAR1 final orf B05 A549 48 5160 SmallIrregular +0.08812949316471831 2.2636884943282605e-16 BR00117020 ELANE final orf D19 A549 48 4715 SmallIrregular +0.08809784596711172 2.8752675186284453e-15 BR00117021 PRKCB final orf K19 A549 48 4390 SmallIrregular +0.08273092369477912 3.038086328937755e-15 BR00117020 CYP1A2 final orf F21 A549 48 4980 SmallIrregular +0.08071920049176103 3.1372802310720382e-15 BR00117021 PRKCB final orf K14 A549 48 5220 SmallIrregular +0.0842301862807412 2.0597947407345468e-14 BR00117021 MAPK8 final orf I14 A549 48 4520 SmallIrregular +0.07960939064237074 9.365113350244933e-14 BR00117021 GABRB2 final orf C06 A549 48 4830 SmallIrregular +0.08012305651308177 4.2789713529727865e-13 BR00117021 PARP3 final orf H21 A549 48 4525 SmallIrregular +0.08392499244982565 7.19629265516774e-13 BR00117021 IMPDH1 final orf N20 A549 48 4050 SmallIrregular +0.07354132451506946 1.1723029894319943e-12 BR00117021 ICAM1 final orf I08 A549 48 5200 SmallIrregular +0.07470119521912351 1.3336322399534346e-12 BR00117020 CYP3A4 final orf K22 A549 48 5020 SmallIrregular +0.07989579243052457 1.4715865716535217e-12 BR00117021 KCNJ1 final orf M03 A549 48 4365 SmallIrregular +0.07533008675623995 1.9069856710623215e-12 BR00117021 TGM2 final orf B07 A549 48 4865 SmallIrregular +0.07628158891323913 3.1718445847342495e-12 BR00117020 KCNJ1 final orf M03 A549 48 4660 SmallIrregular +0.06828954920800294 4.1401365597834595e-12 BR00117020 TUBB3 final orf K05 A549 48 5760 SmallIrregular +0.07092655969325254 6.6690392111602166e-12 BR00117020 CHEK2 final orf F07 A549 48 5225 SmallIrregular +0.07259435654947352 7.0804380828451536e-12 BR00117020 PTGIS final orf H13 A549 48 4990 SmallIrregular +0.0682895476025247 1.3544298247808499e-11 BR00117020 EDNRB final orf M08 A549 48 5500 SmallIrregular +0.07645963797132167 2.8209536210003434e-11 BR00117020 MMP2 final orf J15 A549 48 4255 SmallIrregular +0.06863117870722434 3.416448130204768e-11 BR00117020 KDR final orf A21 A549 48 5260 SmallIrregular +0.07221052631578948 3.436372507386022e-11 BR00117020 GRIN2A final orf I24 A549 48 4750 SmallIrregular +0.07354555433589462 3.91288593476387e-11 BR00117021 PRKCE final orf L14 A549 48 4555 SmallIrregular +0.068865691175653 4.525077050748598e-11 BR00117020 IGF1R final orf H05 A549 48 5160 SmallIrregular +0.06715867158671587 4.757286238808674e-11 BR00117020 FGF1 final orf F22 A549 48 5420 SmallIrregular +0.06848713706310458 6.848336762884377e-11 BR00117020 CDK9 final orf H11 A549 48 5115 SmallIrregular +0.0752064786348396 9.336546119127181e-11 BR00117021 HTR2C final orf G21 A549 48 4195 SmallIrregular +0.07369272877855738 9.718938934871847e-11 BR00117021 PTK2B final orf J18 A549 48 4355 SmallIrregular +0.06906643718063736 9.874788163347363e-11 BR00117020 RET final orf E03 A549 48 4960 SmallIrregular +0.06497189120628626 1.327222684908328e-10 BR00117021 CCR1 final orf P17 A549 48 5535 SmallIrregular +0.06770861173638373 1.8837195701767261e-10 BR00117021 CDC25A final orf I19 A549 48 5025 SmallIrregular +0.0671208489628118 2.2132290909008748e-10 BR00117020 CHRM3 final orf A10 A549 48 5060 SmallIrregular +0.06722502820912364 2.391714095065991e-10 BR00117020 TNNC1 final orf G07 A549 48 5030 SmallIrregular +0.06679118247077417 2.4932174539172347e-10 BR00117020 ITGB2 final orf P21 A549 48 5085 SmallIrregular +0.06427255985267034 3.5768234134479874e-10 BR00117020 SIRT2 final orf G02 A549 48 5430 SmallIrregular +0.0674811232642346 4.3094794668313345e-10 BR00117020 GHSR final orf A17 A549 48 4865 SmallIrregular +0.06453812374113008 4.670189575608597e-10 BR00117021 FLT3 final orf K13 A549 48 5300 SmallIrregular +0.06470028544243578 5.515844793544941e-10 BR00117020 LPAR1 final orf B05 A549 48 5255 SmallIrregular +0.06864249911607495 5.671832037163807e-10 BR00117021 KRAS final orf F08 A549 48 4650 SmallIrregular +0.06800981488515595 6.668672688344985e-10 BR00117021 ERBB2 final orf I20 A549 48 4705 SmallIrregular +0.057972917165228656 1.4986728781716649e-09 BR00117021 P2RY12 final orf B01 A549 48 6220 SmallIrregular +0.06259686899319702 1.5835276485212584e-09 BR00117021 FFAR4 final orf I16 A549 48 5325 SmallIrregular +0.0650185926237461 1.7862895110578967e-09 BR00117020 KCNN1 final orf O10 A549 48 4900 SmallIrregular +0.0628583737652453 2.9305240362852317e-09 BR00117021 USP1 final orf G11 A549 48 5130 SmallIrregular +0.06168230175791613 3.5063025087520512e-09 BR00117021 TNNC1 final orf G07 A549 48 5290 SmallIrregular +0.06607007870938345 3.6684347019809737e-09 BR00117020 PLK1 final orf L11 A549 48 4580 SmallIrregular +0.06345381526104418 3.871132165123966e-09 BR00117020 TGFBR1 final orf I23 A549 48 4980 SmallIrregular +0.05988807333193709 4.401547993360305e-09 BR00117020 KRAS final orf D17 A549 48 5550 SmallIrregular +0.06022604462685211 4.894602053191421e-09 BR00117021 ADH1C final orf O04 A549 48 5445 SmallIrregular +0.060405156537753225 4.919873631555715e-09 BR00117020 RNASE1 final orf I18 A549 48 5430 SmallIrregular +0.06555924695459579 7.382442631671521e-09 BR00117021 S100B final orf M20 A549 48 4515 SmallIrregular +0.062267048208025796 7.922140548117174e-09 BR00117021 P3H1 final orf P24 A549 48 4970 SmallIrregular +0.061494328902752346 7.989018315242166e-09 BR00117021 TGFBR1 final orf O14 A549 48 5085 SmallIrregular +0.06096153846153846 8.016320289017988e-09 BR00117020 MAPK8 final orf I13 A549 48 5200 SmallIrregular +0.06090297790585975 8.16677554926868e-09 BR00117020 AURKB final orf H10 A549 48 5205 SmallIrregular +0.061148814369663546 1.4190233100775915e-08 BR00117020 HRH4 final orf O06 A549 48 5010 SmallIrregular +0.06851385390428212 1.5932959205591984e-08 BR00117021 HIF1A final orf C23 A549 48 3970 SmallIrregular +0.06197353599595503 1.805319369606495e-08 BR00117020 TNF final orf C18 A549 48 4815 SmallIrregular +0.0619206506393256 1.9618188170688092e-08 BR00117021 TUBB3 final orf G06 A549 48 4790 SmallIrregular +0.06121098430562067 2.2829723234200515e-08 BR00117021 USP1 final orf E12 A549 48 4855 SmallIrregular +0.06491334851697689 2.711123520146794e-08 BR00117021 KCNH7 final orf A22 A549 48 4280 SmallIrregular +0.06293859649122807 2.830605293343413e-08 BR00117021 CYP2A6 final orf A20 A549 48 4560 SmallIrregular +0.0633878691141261 2.857658515632553e-08 BR00117020 PPAT final orf F11 A549 48 4475 SmallIrregular +0.05825056090157397 2.998179838344618e-08 BR00117020 GUCY1B1 final orf J08 A549 48 5280 SmallIrregular +0.058531935176358435 3.1141776767734844e-08 BR00117020 HDAC3 final orf N06 A549 48 5245 SmallIrregular +0.06057982201773052 3.327536219463571e-08 BR00117020 CSF1R final orf D14 A549 48 4860 SmallIrregular +0.0561765148286495 3.3422321265292856e-08 BR00117021 KCNQ2 final orf K02 A549 48 5650 SmallIrregular +0.05434603207528022 3.9022623159432254e-08 BR00117020 TGM2 final orf H02 A549 48 5990 SmallIrregular +0.05852798956512618 4.487993143452118e-08 BR00117020 VEGFA final orf B09 A549 48 5130 SmallIrregular +0.05904345176553297 4.82130603515881e-08 BR00117021 FGF1 final orf F03 A549 48 5020 SmallIrregular +0.060915867944621935 5.3814488201287525e-08 BR00117021 BRAF final orf C05 A549 48 4695 SmallIrregular +0.060208333333333336 5.5008754630352537e-08 BR00117021 RNASE1 final orf G17 A549 48 4800 SmallIrregular +0.054677286840426616 5.699736465647529e-08 BR00117020 GPR119 final orf N02 A549 48 5785 SmallIrregular +0.05672240253414019 5.984514012119036e-08 BR00117021 S1PR4 final orf K18 A549 48 5360 SmallIrregular +0.05679475164011247 6.66833341438044e-08 BR00117021 CATSPER4 final orf P07 A549 48 5335 SmallIrregular +0.06033345024048166 7.759568615670789e-08 BR00117020 AKR1B1 final orf L10 A549 48 4680 SmallIrregular +0.061643815058049486 7.897516702767221e-08 BR00117020 AVPR1A final orf H22 A549 48 4470 SmallIrregular +0.06418348187084431 8.005937191049288e-08 BR00117021 OPRL1 final orf A23 A549 48 4110 SmallIrregular +0.05527959077391816 8.011231081838311e-08 BR00117021 GPR119 final orf N02 A549 48 5550 SmallIrregular +0.06056034482758621 8.067072690164487e-08 BR00117020 CACNG1 final orf A16 A549 48 4640 SmallIrregular +0.060748438476323524 8.293355473226049e-08 BR00117021 PRKCE final orf J19 A549 48 4585 SmallIrregular +0.06564131768915517 8.489309583540717e-08 BR00117020 CDK4 final orf B21 A549 48 3920 SmallIrregular +0.06269639917048611 9.176733921241629e-08 BR00117021 GABRB2 final orf C19 A549 48 4285 SmallIrregular +0.058367453918030145 9.81918957950407e-08 BR00117020 KCNN4 final orf A06 A549 48 4910 SmallIrregular +0.05715073612387622 9.999950783325224e-08 BR00117021 OPRM1 final orf A09 A549 48 5135 SmallIrregular +0.06023194595083153 1.034836178196056e-07 BR00117021 CDK7 final orf K06 A549 48 4610 SmallIrregular +0.057558875030274154 1.1024890475564466e-07 BR00117021 MET final orf C03 A549 48 5015 SmallIrregular +0.05764685710421795 1.2438933433977087e-07 BR00117020 HSP90AA1 final orf C14 A549 48 4985 SmallIrregular +0.057777777777777775 1.3221564216793389e-07 BR00117021 PTGIR final orf C07 A549 48 4950 SmallIrregular +0.05848809123918294 1.3864973824138964e-07 BR00117021 JAK1 final orf H17 A549 48 4810 SmallIrregular +0.06087706285345877 1.6709451186253505e-07 BR00117020 CCR1 final orf F24 A549 48 4380 SmallIrregular 0.11939538269585243 2.967122922253693e-64 BR00118050 HDAC3 final orf N21 A549 96 10275 ADCCM 0.13033846153846154 1.5448108579532788e-60 BR00118050 HTR3A final orf J23 A549 96 8125 ADCCM 0.1072449188534786 2.6621514700201866e-48 BR00117006 GPR119 final orf N23 A549 96 9560 ADCCM @@ -1359,6 +13509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.09852561000458458 4.6282375500942686e-40 BR00118050 ITGB2 final orf P21 A549 96 9380 ADCCM 0.10173269575803356 3.5869596188154725e-38 BR00118050 PDE7A final orf J11 A549 96 8380 ADCCM 0.09276858276858277 1.7211710170442972e-36 BR00117006 HDAC3 final orf N21 A549 96 9620 ADCCM +0.09616630144452691 4.902403069282063e-36 BR00117006 CHRM2 final orf B03 A549 96 8835 ADCCM +0.08674635535360892 2.928699019133968e-35 BR00118050 TBXAS1 final orf P23 A549 96 10635 ADCCM +0.08951224085664689 1.7974669439359363e-32 BR00117006 PDPK1 final orf H15 A549 96 9190 ADCCM +0.08470392438254365 2.702292620558609e-32 BR00117006 BRD4 final orf N17 A549 96 10205 ADCCM +0.09160047427867116 3.0362583117349963e-30 BR00118050 GPR119 final orf N02 A549 96 8160 ADCCM +0.1276039415679834 4.799906685300518e-29 BR00118050 CSF1R final orf D14 A549 96 4025 ADCCM +0.09267015706806282 5.857506631491791e-29 BR00118050 PTK2B final orf N19 A549 96 7640 ADCCM +0.08533338631980399 6.854398415737904e-29 BR00117006 CDK4 final orf B21 A549 96 8975 ADCCM +0.08984008587819593 7.253264555845001e-29 BR00118050 ALDH2 final orf P13 A549 96 8095 ADCCM +0.08759386693027552 8.800188398788655e-29 BR00117006 AURKB final orf L19 A549 96 8490 ADCCM +0.09387682474144207 1.5889412141651627e-28 BR00118050 PDPK1 final orf H15 A549 96 7325 ADCCM +0.08895892388842148 1.7444147352342819e-28 BR00117006 CSF1R final orf J07 A549 96 8135 ADCCM +0.08962334938261828 9.03069098396936e-28 BR00117006 GJB4 final orf H23 A549 96 7825 ADCCM +0.08771284537542533 1.0197568807133399e-26 BR00117006 CLK1 final orf J17 A549 96 7840 ADCCM +0.08492760362708614 1.0374797494744776e-25 BR00117006 SSTR2 final orf J01 A549 96 8045 ADCCM +0.08386981901098782 1.672599390896679e-25 BR00118050 AKR1B1 final orf L17 A549 96 8185 ADCCM +0.07849727990224831 3.960861447231276e-25 BR00118050 BTK final orf N01 A549 96 9210 ADCCM +0.08812873768579865 2.484914473887712e-24 BR00117006 FOXM1 final orf J02 A549 96 7070 ADCCM +0.07738804426159926 8.636436801791932e-24 BR00117006 PDE7A final orf J11 A549 96 8955 ADCCM +0.09615376307172546 1.6849118688743753e-22 BR00118050 PPAT final orf F11 A549 96 5485 ADCCM +0.07624349936604398 4.561154432042095e-22 BR00117006 CDK9 final orf H11 A549 96 8545 ADCCM +0.07512149938151098 1.3289027910250343e-21 BR00117006 S1PR1 final orf L01 A549 96 8615 ADCCM +0.08454489319659295 1.5534302350687586e-21 BR00117006 CA14 final orf N07 A549 96 6785 ADCCM +0.07493325750698258 6.083487202796549e-21 BR00118050 ANXA1 final orf N24 A549 96 8395 ADCCM +0.08642131645174446 1.085966944436326e-20 BR00117006 KCNN1 final orf A01 A549 96 6220 ADCCM +0.08274953370868975 2.095803570131124e-20 BR00117006 RPL23A final orf I07 A549 96 6690 ADCCM +0.07361052030251734 6.102119853731569e-20 BR00117006 JAK1 final orf H17 A549 96 8280 ADCCM +0.09856719516684874 2.608660719317266e-19 BR00118050 LCK final orf B18 A549 96 4460 ADCCM +0.06920529801324503 2.768316553429943e-19 BR00117006 ASIC1 final orf L21 A549 96 9060 ADCCM +0.07416642048988961 3.3341484000798497e-19 BR00118050 GJB4 final orf H23 A549 96 7840 ADCCM +0.09862387215328391 4.413492182968121e-19 BR00118050 UGT1A9 final orf E24 A549 96 4400 ADCCM +0.08711511484740836 4.848465144080025e-19 BR00118050 CTSG final orf J12 A549 96 5630 ADCCM +0.09119373776908024 6.626379902000791e-19 BR00118050 SLC29A1 final orf L20 A549 96 5110 ADCCM +0.08496176720475786 6.778435212747681e-19 BR00117006 GHSR final orf C24 A549 96 5885 ADCCM +0.07241833891453502 7.674196469517666e-19 BR00118050 DDR2 final orf M02 A549 96 8070 ADCCM +0.06909130348492774 9.215513371162217e-19 BR00117006 ALDH2 final orf P13 A549 96 8835 ADCCM +0.07001806302750029 9.50039173236053e-19 BR00117006 PTGIS final orf H13 A549 96 8580 ADCCM +0.07458305537024683 1.5095336879069043e-18 BR00117006 PARP3 final orf H21 A549 96 7495 ADCCM +0.06785049067167304 6.3741356434258336e-18 BR00117006 PTK2B final orf N19 A549 96 8725 ADCCM +0.0673659037849998 6.912416497891728e-18 BR00117006 PLD1 final orf L05 A549 96 8840 ADCCM +0.0788366582514016 8.24010856959844e-18 BR00117006 DHH final orf E08 A549 96 6425 ADCCM +0.08119120218005542 1.8926077066096985e-17 BR00117006 RPL23A final orf G16 A549 96 5920 ADCCM +0.09223173999590431 2.7722869658600874e-17 BR00118050 KRAS final orf F08 A549 96 4540 ADCCM +0.07577658303464756 3.570544490232438e-17 BR00117006 ERBB2 final orf I20 A549 96 6700 ADCCM +0.07602011235660959 5.857019862486662e-17 BR00117006 HIF1A final orf C23 A549 96 6570 ADCCM +0.08473933649289099 6.798826698359469e-17 BR00118050 PTGIS final orf H13 A549 96 5275 ADCCM +0.07986406117247238 9.623225138164967e-17 BR00117006 BRD4 final orf F14 A549 96 5885 ADCCM +0.07331996374566287 1.0339252571728709e-16 BR00118050 PTK2B final orf J18 A549 96 6955 ADCCM +0.07669350868354342 1.202206646227069e-16 BR00118050 ADH1C final orf M23 A549 96 6330 ADCCM +0.08728968795925997 1.5619524267032116e-16 BR00118050 DNMT3A final orf H07 A549 96 4855 ADCCM +0.07719197037029896 2.6238068691736475e-16 BR00118050 MAPK14 final orf G22 A549 96 6110 ADCCM +0.08580121703853956 3.318871375276717e-16 BR00118050 IL1B final orf G08 A549 96 4930 ADCCM +0.06797387905917736 3.795831504980611e-16 BR00117006 FPR1 final orf D21 A549 96 7805 ADCCM +0.0968670560985753 4.845137294856809e-16 BR00117006 P2RY12 final orf B24 A549 96 3810 ADCCM +0.08731979436753581 5.108772671998707e-16 BR00118050 MAPK8 final orf I13 A549 96 4685 ADCCM +0.07678771758404807 5.914220503985295e-16 BR00117006 ANXA1 final orf D23 A549 96 6040 ADCCM +0.07459735467456387 6.690812047148005e-16 BR00117006 TUBB final orf E19 A549 96 6390 ADCCM +0.0888123796831038 6.972649539366357e-16 BR00117006 TNNC1 final orf M18 A549 96 4500 ADCCM +0.07802608951231944 1.0678895503445093e-15 BR00117006 BRAF final orf I10 A549 96 5765 ADCCM +0.08300422479843007 1.503436671048761e-15 BR00117006 GABRB2 final orf C06 A549 96 5035 ADCCM +0.067580501889977 2.1360898502567758e-15 BR00117006 LCK final orf B18 A549 96 7535 ADCCM +0.07122318824325037 3.1272894792113553e-15 BR00118050 P3H1 final orf F23 A549 96 6705 ADCCM +0.07919424434379056 4.458834268263118e-15 BR00117006 AKR1C1 final orf A24 A549 96 5360 ADCCM +0.07556116609575969 5.017203199915536e-15 BR00117006 PORCN final orf D22 A549 96 5870 ADCCM +0.08543029168267445 8.214468896788237e-15 BR00118050 GUCY1B1 final orf F05 A549 96 4515 ADCCM +0.07277617061777561 1.0499381634574627e-14 BR00118050 TNNC1 final orf M18 A549 96 6190 ADCCM +0.07243898101957444 1.1500511046968978e-14 BR00117006 ICAM1 final orf I08 A549 96 6235 ADCCM +0.06390969432872713 1.2512139193639187e-14 BR00118050 CDK9 final orf N22 A549 96 7990 ADCCM +0.07326844031653405 1.2673016465755939e-14 BR00117006 HPGDS final orf O24 A549 96 6080 ADCCM +0.06907749077490775 1.7819440201887646e-14 BR00118050 ALK final orf J13 A549 96 6775 ADCCM +0.07474048442906574 1.8480329404808654e-14 BR00117006 PTGIS final orf F16 A549 96 5780 ADCCM +0.06853012917118839 1.883637259056072e-14 BR00118050 CACNA2D3 final orf L02 A549 96 6860 ADCCM +0.07930587249870755 2.2017282035735046e-14 BR00117006 CYP2A6 final orf A20 A549 96 5095 ADCCM +0.07601195212323174 2.4627646339350653e-14 BR00118050 UGT1A9 final orf O09 A549 96 5520 ADCCM +0.058623503808487486 3.6581550311969e-14 BR00117006 IMPDH1 final orf L13 A549 96 9190 ADCCM +0.07756227871956965 3.96869129237694e-14 BR00118050 COMT final orf B10 A549 96 5225 ADCCM +0.12131147540983607 4.218823854405257e-14 BR00118050 ANXA1 final orf D23 A549 96 2135 ADCCM +0.0645244674429843 5.935850940120185e-14 BR00118050 CACNB4 final orf M01 A549 96 7455 ADCCM +0.0780684842586726 6.37876330843572e-14 BR00117006 ITGB2 final orf B12 A549 96 5075 ADCCM +0.07357636558452452 7.542604477919074e-14 BR00117006 SLC29A1 final orf L20 A549 96 5695 ADCCM +0.07380870877690071 1.2746841547896668e-13 BR00118050 SCNN1G final orf A04 A549 96 5565 ADCCM +0.08043243243243244 1.9675481154814309e-13 BR00118050 CHRM3 final orf A10 A549 96 4625 ADCCM +0.07554635194075479 2.53444242320469e-13 BR00118050 MME final orf I11 A549 96 5185 ADCCM +0.06918826637136496 3.8619873050689387e-13 BR00118050 SSTR2 final orf D02 A549 96 6105 ADCCM +0.07591695060179074 6.611578074305747e-13 BR00118050 SLC7A11 final orf G24 A549 96 4960 ADCCM +0.06685038129880953 8.922054390715913e-13 BR00117006 MAPK8 final orf I14 A549 96 6350 ADCCM +0.06337223094094918 1.415904106641393e-12 BR00117006 ADRA2B final orf J03 A549 96 6945 ADCCM +0.06573643410852713 1.5433829161196308e-12 BR00118050 CLK1 final orf J17 A549 96 6450 ADCCM +0.07506708716897303 1.600488315867435e-12 BR00118050 KCNK1 final orf M15 A549 96 4925 ADCCM +0.06982101197220288 1.6381289358997458e-12 BR00117006 ADA final orf P04 A549 96 5680 ADCCM 0.13308422891143387 7.383055541142164e-42 BR00117006 AKR1C1 final orf A24 A549 96 5360 Anaphase 0.11020159800151115 2.002701018241484e-32 BR00117006 ANXA1 final orf D23 A549 96 6040 Anaphase 0.11490593121983995 4.413144996125511e-25 BR00117006 DYRK1B final orf M12 A549 96 4280 Anaphase @@ -1369,6 +13609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.06728567697064654 2.9464727411476104e-19 BR00117006 GPR119 final orf N23 A549 96 9560 Anaphase 0.07930206842053951 3.6230864520683663e-19 BR00118050 ASIC1 final orf L21 A549 96 6840 Anaphase 0.06845810612279367 1.0130812287705909e-18 BR00117006 CDK4 final orf B21 A549 96 8975 Anaphase +0.07164179104477612 2.3191660393396567e-18 BR00118050 BRD4 final orf N17 A549 96 8040 Anaphase +0.07609275105928438 6.302287624753494e-18 BR00118050 KCNQ2 final orf K02 A549 96 6935 Anaphase +0.09475332355180051 8.180556484117469e-18 BR00117006 DYRK1B final orf G13 A549 96 4445 Anaphase +0.07829457364341086 1.2981151005356132e-17 BR00118050 CLK1 final orf J17 A549 96 6450 Anaphase +0.10883271805711649 2.2037351443890876e-17 BR00118050 DYRK1B final orf G13 A549 96 3280 Anaphase +0.0735565492392891 9.051933029044953e-17 BR00117006 USP1 final orf E12 A549 96 6935 Anaphase +0.0706805762382619 1.210421325562323e-16 BR00118050 CACNB4 final orf M01 A549 96 7455 Anaphase +0.07171242507933918 1.626899736768461e-16 BR00118050 TBXAS1 final orf J24 A549 96 7175 Anaphase +0.07341587764020394 1.652513512854681e-16 BR00117006 CHRM3 final orf A10 A549 96 6865 Anaphase +0.06912183385348394 5.749022119981168e-16 BR00117006 DHH final orf G05 A549 96 7460 Anaphase +0.07673869868548287 2.631924599068743e-15 BR00118050 PDE7A final orf F20 A549 96 5795 Anaphase +0.07626059801512201 5.8012715389644e-15 BR00118050 DYRK1B final orf M12 A549 96 5735 Anaphase +0.07070982427286084 1.0317619952032527e-14 BR00118050 HCK final orf O01 A549 96 6555 Anaphase +0.08874516873911809 3.109347755289215e-14 BR00118050 CSF1R final orf D14 A549 96 4025 Anaphase +0.09090233080780957 3.6504707609835474e-14 BR00117006 P2RY12 final orf B24 A549 96 3810 Anaphase +0.07736561909668556 6.684856347656954e-14 BR00118050 S1PR1 final orf P22 A549 96 5175 Anaphase +0.07631578947368421 6.806664426520881e-14 BR00118050 CYP1A2 final orf N12 A549 96 5320 Anaphase +0.06487452290450765 7.487061260515684e-14 BR00117006 AGER final orf H09 A549 96 7315 Anaphase +0.06032374606394747 9.873578725323317e-14 BR00118050 ANXA1 final orf N24 A549 96 8395 Anaphase +0.067382470223253 1.0855763995491206e-13 BR00118050 P3H1 final orf F23 A549 96 6705 Anaphase +0.07030197751847236 1.336091021799769e-13 BR00118050 MAPK14 final orf G22 A549 96 6110 Anaphase +0.0685515540748314 1.6120394518559176e-13 BR00117006 AKR1B1 final orf L10 A549 96 6390 Anaphase +0.060492334246049925 3.633854896417646e-13 BR00118050 CDK9 final orf N22 A549 96 7990 Anaphase +0.06385705138403115 4.799436019296229e-13 BR00118050 CA5A final orf B02 A549 96 7110 Anaphase +0.060243765978679024 5.823036216060737e-13 BR00117006 PPAT final orf H14 A549 96 7930 Anaphase +0.05870098039215686 1.2116149491149817e-12 BR00117006 F10 final orf C09 A549 96 8160 Anaphase +0.062116851815559385 1.4310876350313576e-12 BR00118050 HSD11B1 final orf C02 A549 96 7235 Anaphase +0.0772115219937141 1.686424115698217e-12 BR00117006 UGT1A9 final orf E24 A549 96 4650 Anaphase +0.07802984898302746 3.3840203787369154e-12 BR00118050 GRIN2A final orf A05 A549 96 4430 Anaphase +0.06467930117714447 3.543489046756892e-12 BR00118050 ADRA2B final orf J03 A549 96 6440 Anaphase +0.06319704151075133 3.6133603288022347e-12 BR00117006 CYP3A4 final orf K22 A549 96 6755 Anaphase +0.05744642348196847 5.149328229218966e-12 BR00117006 CACNA2D3 final orf P19 A549 96 8055 Anaphase +0.11100702576112412 7.152071213656224e-12 BR00118050 ANXA1 final orf D23 A549 96 2135 Anaphase +0.058139001929258534 7.412401654259271e-12 BR00117006 FLT3 final orf K13 A549 96 7765 Anaphase +0.05949966193373901 8.4200963210895e-12 BR00117006 ATP5F1D final orf G14 A549 96 7395 Anaphase +0.05716302149411598 1.2799386427840205e-11 BR00117006 P2RY12 final orf B01 A549 96 7860 Anaphase +0.05241654047470905 2.075375740097348e-11 BR00117006 PDPK1 final orf H15 A549 96 9190 Anaphase +0.06431501230516817 2.2139119397044457e-11 BR00118050 PTPN2 final orf I02 A549 96 6095 Anaphase +0.05572139303482587 2.849147762963966e-11 BR00117006 MAPK14 final orf G15 A549 96 8040 Anaphase +0.0692489972417072 3.4849356377684895e-11 BR00117006 KCNH7 final orf A22 A549 96 5150 Anaphase +0.05621597514905861 5.828076807551101e-11 BR00117006 BTK final orf N01 A549 96 7655 Anaphase +0.05670446964643095 6.758914672685677e-11 BR00117006 PARP3 final orf H21 A549 96 7495 Anaphase +0.18805092152070882 9.936697273398218e-11 BR00118049 DYRK1B final orf M12 A549 96 663 Anaphase +0.09049295774647888 1.5443034833231528e-10 BR00118050 S1PR2 final orf B06 A549 96 2840 Anaphase +0.05788732960882619 1.6656841586721848e-10 BR00117006 ADA final orf P03 A549 96 6910 Anaphase +0.07408691463792891 1.8672453899634329e-10 BR00118050 GLRA3 final orf E05 A549 96 4185 Anaphase +0.07052139625554232 2.3982182506502753e-10 BR00118050 KDR final orf O02 A549 96 4585 Anaphase +0.06005250292822321 2.7782155747516296e-10 BR00118050 F10 final orf C09 A549 96 6285 Anaphase +0.05628445941900226 4.062385918243077e-10 BR00118050 HPGDS final orf O21 A549 96 7030 Anaphase +0.06294964028776978 5.33364525571494e-10 BR00118050 BTK final orf P10 A549 96 5560 Anaphase +0.06259867895475472 5.655356872451666e-10 BR00118050 AKR1C1 final orf A24 A549 96 5590 Anaphase +0.06429677965716114 7.522176653255568e-10 BR00117006 LYN final orf M05 A549 96 5220 Anaphase +0.05822779048884297 7.855288768207433e-10 BR00117006 CSK final orf P05 A549 96 6375 Anaphase +0.046781363010047615 9.629331412813574e-10 BR00117006 EZH2 final orf D03 A549 96 9780 Anaphase +0.055566233828086994 1.191397751942523e-09 BR00118050 CACNA2D3 final orf L02 A549 96 6860 Anaphase +0.05428938854761467 1.2171494881020592e-09 BR00117006 BAX final orf K17 A549 96 7190 Anaphase +0.05057148995984663 1.7441221358976151e-09 BR00117006 RPL3 final orf G09 A549 96 8140 Anaphase +0.05665896843725943 1.7442942876294127e-09 BR00117006 P3H1 final orf F23 A549 96 6495 Anaphase +0.06945131899759849 3.2430585770135505e-09 BR00117006 CA5A final orf B23 A549 96 4180 Anaphase +0.05064536814598305 3.5131620782800384e-09 BR00118050 GJB4 final orf H23 A549 96 7840 Anaphase +0.05438202247191011 5.298787166314551e-09 BR00118050 DCK final orf D05 A549 96 6675 Anaphase +0.05546573767584454 6.286953870926381e-09 BR00117006 MAPK8 final orf I14 A549 96 6350 Anaphase +0.046070008362288827 6.364759034109766e-09 BR00117006 IMPDH1 final orf L13 A549 96 9190 Anaphase +0.05386060736393382 7.853570463278444e-09 BR00118050 ABL1 final orf M24 A549 96 6640 Anaphase +0.04627107602069494 8.854087738622913e-09 BR00117006 PDE7A final orf J11 A549 96 8955 Anaphase +0.061689563714535295 9.13018573603847e-09 BR00117006 OPRM1 final orf A09 A549 96 5025 Anaphase +0.05069974732948861 1.0293853921554268e-08 BR00117006 SSTR2 final orf D02 A549 96 7390 Anaphase +0.046605420125205084 1.1310088368592599e-08 BR00117006 PTK2B final orf N19 A549 96 8725 Anaphase +0.04308864897709097 1.1422705236665209e-08 BR00117006 BRD4 final orf N17 A549 96 10205 Anaphase +0.05707132993073796 1.1550947184691436e-08 BR00118050 NTRK1 final orf P02 A549 96 5805 Anaphase +0.055373540068246144 1.1727083946158304e-08 BR00117006 GUCY1B1 final orf J08 A549 96 6160 Anaphase +0.044233658233658234 1.2672629182753287e-08 BR00117006 HDAC3 final orf N21 A549 96 9620 Anaphase +0.05467536920363918 1.9190127058886812e-08 BR00118050 CACNA2D3 final orf P19 A549 96 6155 Anaphase +0.05127647114807227 2.188213665785705e-08 BR00118050 PTK2B final orf J18 A549 96 6955 Anaphase +0.37032967032967035 2.313890624271291e-08 BR00118049 DHH final orf E08 A549 96 130 Anaphase +0.05082145347310468 2.400862901315751e-08 BR00117006 CDK2 final orf J04 A549 96 7050 Anaphase +0.045238345083095245 2.597766646951393e-08 BR00117006 ALDH2 final orf P13 A549 96 8835 Anaphase +0.05261229853132629 2.6418613817275527e-08 BR00117006 MME final orf K20 A549 96 6545 Anaphase +0.058626844518920945 3.2855221750876516e-08 BR00118050 TGM2 final orf B07 A549 96 5190 Anaphase +0.056807935076645624 3.3578716376987804e-08 BR00117006 PAK1 final orf L12 A549 96 5545 Anaphase +0.057905056085207754 3.548470214595239e-08 BR00118050 PORCN final orf D22 A549 96 5305 Anaphase +0.04919028955124115 5.8160308389217395e-08 BR00117006 FFAR4 final orf C17 A549 96 7155 Anaphase +0.05178658608029995 6.727984562533962e-08 BR00118050 AGER final orf H09 A549 96 6400 Anaphase +0.062266623094440754 6.819714548851247e-08 BR00117006 CLK1 final orf D08 A549 96 4420 Anaphase +0.0481731280925765 6.947117306614883e-08 BR00117006 MAPK8 final orf I13 A549 96 7380 Anaphase +0.04943009702439822 7.136603235143319e-08 BR00117006 HTR2C final orf M06 A549 96 6990 Anaphase +0.06355770557883032 8.560097455365453e-08 BR00117006 HSP90AB1 final orf B16 A549 96 4185 Anaphase +0.0601197769354968 8.652056801162331e-08 BR00118050 KCNK1 final orf C22 A549 96 4675 Anaphase +0.046996792926172835 9.818052090712499e-08 BR00117006 TUBB4B final orf E07 A549 96 7595 Anaphase +0.04961444453770098 1.0697099706344955e-07 BR00117006 FLT3 final orf E14 A549 96 6785 Anaphase 0.15926507939356288 2.9736827605325393e-93 BR00118050 PDE7A final orf J11 A549 96 8380 Apoptosis 0.139854611559582 4.2200590303586566e-88 BR00118050 HDAC3 final orf N21 A549 96 10275 Apoptosis 0.13690545541550148 7.153517594758068e-84 BR00117006 BRD4 final orf N17 A549 96 10205 Apoptosis @@ -1379,6 +13709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.13893034825870645 4.905529763635878e-68 BR00118050 BRD4 final orf N17 A549 96 8040 Apoptosis 0.13117718728581435 4.217237232924389e-64 BR00117006 AURKB final orf L19 A549 96 8490 Apoptosis 0.1369803857694098 5.0432560168677386e-64 BR00118050 GAA final orf N15 A549 96 7775 Apoptosis +0.1249443725393868 2.3602825053986448e-61 BR00117006 PDE7A final orf J11 A549 96 8955 Apoptosis +0.12048540027660654 6.705280820208237e-61 BR00117006 GPR119 final orf N23 A549 96 9560 Apoptosis +0.12579088774652192 1.387006785064213e-60 BR00117006 PTK2B final orf N19 A549 96 8725 Apoptosis +0.12063401340621605 3.0977492679510835e-60 BR00118050 AURKB final orf L19 A549 96 9430 Apoptosis +0.16035864423200502 1.4160060124904215e-57 BR00117006 CYP2A6 final orf A20 A549 96 5095 Apoptosis +0.11628609228609228 4.0877583577644194e-57 BR00117006 HDAC3 final orf N21 A549 96 9620 Apoptosis +0.1159613130816409 1.5367239604035439e-56 BR00118050 S1PR1 final orf L01 A549 96 9575 Apoptosis +0.12538698234884388 1.7832216766514086e-56 BR00118050 AKR1B1 final orf L17 A549 96 8185 Apoptosis +0.14460806084951128 1.7619579710611383e-55 BR00117006 SIRT2 final orf A07 A549 96 6040 Apoptosis +0.1476286679703387 1.9389531928448338e-51 BR00117006 AKR1C1 final orf A24 A549 96 5360 Apoptosis +0.1383177570093458 1.780749454974318e-49 BR00117006 GHSR final orf C24 A549 96 5885 Apoptosis +0.1089391687345816 6.877190903602865e-49 BR00118050 ITGB2 final orf P21 A549 96 9380 Apoptosis +0.16878526988953244 6.566923254584903e-48 BR00117006 P2RY12 final orf B24 A549 96 3810 Apoptosis +0.12706395071920745 1.5516204781525734e-46 BR00117006 PNLIP final orf L22 A549 96 6545 Apoptosis +0.11243418302255347 2.195109756485388e-45 BR00118050 GPR119 final orf N02 A549 96 8160 Apoptosis +0.1428596801720232 3.0652668734080333e-45 BR00117006 GABRB2 final orf C06 A549 96 5035 Apoptosis +0.1078288741874935 1.1396332020992236e-43 BR00117006 CDK9 final orf H11 A549 96 8545 Apoptosis +0.11614383548580956 1.1773888694585922e-41 BR00117006 PARP3 final orf J20 A549 96 7020 Apoptosis +0.16078626203081464 2.079770073932011e-40 BR00118050 OPRL1 final orf A23 A549 96 3545 Apoptosis +0.11163209057527654 3.5807082681045043e-40 BR00118050 PDPK1 final orf H15 A549 96 7325 Apoptosis +0.10730186195247565 1.3196779879788654e-39 BR00117006 FPR1 final orf D21 A549 96 7805 Apoptosis +0.13839260503890502 2.7222434388946347e-39 BR00117006 UGT1A9 final orf E24 A549 96 4650 Apoptosis +0.10656514327889595 3.611182564562685e-39 BR00117006 CLK1 final orf J17 A549 96 7840 Apoptosis +0.13052837573385517 2.4317765754542245e-38 BR00118050 SLC29A1 final orf L20 A549 96 5110 Apoptosis +0.1333542395633899 3.6417171261131783e-38 BR00117006 CACNG1 final orf A16 A549 96 4860 Apoptosis +0.11563747758633376 1.0105346818763499e-36 BR00118050 PNLIP final orf L22 A549 96 6225 Apoptosis +0.10925417841749135 4.126267806899164e-36 BR00118050 CACNA2D3 final orf L02 A549 96 6860 Apoptosis +0.10112208914497346 2.993686525690948e-35 BR00117006 GJB4 final orf H23 A549 96 7825 Apoptosis +0.09980009252776484 2.011070061429665e-34 BR00118050 GJB4 final orf H23 A549 96 7840 Apoptosis +0.13877850906980477 2.901174821596109e-34 BR00118050 CSF1R final orf D14 A549 96 4025 Apoptosis +0.1175931348424803 4.271827450249789e-34 BR00118050 AKR1C1 final orf A24 A549 96 5590 Apoptosis +0.10834381950392483 8.223245779136224e-34 BR00118050 FPR1 final orf D21 A549 96 6525 Apoptosis +0.09341621296974648 6.1036809470524576e-33 BR00117006 GAA final orf N15 A549 96 8550 Apoptosis +0.12076295905114845 7.646399251146421e-33 BR00117006 KDR final orf A21 A549 96 5105 Apoptosis +0.10420664206642066 1.96935981315957e-32 BR00118050 ALK final orf J13 A549 96 6775 Apoptosis +0.10749621006744607 8.890855581821118e-32 BR00117006 KCNN1 final orf A01 A549 96 6220 Apoptosis +0.11537272979334386 1.7725997581461547e-31 BR00117006 P3H1 final orf P24 A549 96 5355 Apoptosis +0.08902677100033903 2.119417835289828e-31 BR00117006 CDK4 final orf B21 A549 96 8975 Apoptosis +0.11063293832910517 3.7299058345530065e-31 BR00117006 BRAF final orf I10 A549 96 5765 Apoptosis +0.08746156235587363 5.198934336251876e-31 BR00117006 IMPDH1 final orf L13 A549 96 9190 Apoptosis +0.11187029129935848 1.652947566086136e-30 BR00118050 UGT1A9 final orf O09 A549 96 5520 Apoptosis +0.10639720892900517 4.6028876408135884e-30 BR00118050 KCNN4 final orf A06 A549 96 6015 Apoptosis +0.09126812431417276 6.696948283082883e-30 BR00117006 CSF1R final orf J07 A549 96 8135 Apoptosis +0.1071237209079275 5.966854009310977e-29 BR00118050 S1PR4 final orf M17 A549 96 5705 Apoptosis +0.08718700374199866 6.00214298854711e-29 BR00117006 LPAR1 final orf B05 A549 96 8610 Apoptosis +0.1215005048835967 6.110958248529641e-29 BR00118050 GRIN2A final orf A05 A549 96 4430 Apoptosis +0.10731984581743477 2.659290898051581e-28 BR00117006 IL1B final orf G08 A549 96 5555 Apoptosis +0.10433708368080723 3.11258081422003e-28 BR00117006 PORCN final orf D22 A549 96 5870 Apoptosis +0.07735904713120456 4.028044153211835e-28 BR00118050 TBXAS1 final orf P23 A549 96 10635 Apoptosis +0.09765985002578062 4.534657368315386e-28 BR00118050 PDE3A final orf O19 A549 96 6660 Apoptosis +0.1211237695016321 4.614638201093298e-28 BR00118050 FLT3 final orf K13 A549 96 4320 Apoptosis +0.12163712837159786 4.853704752352292e-28 BR00117006 DYRK1B final orf M12 A549 96 4280 Apoptosis +0.09603522668156993 7.468533863872201e-28 BR00118050 PRKCE final orf J19 A549 96 6825 Apoptosis +0.09948263117136191 1.2501092006609947e-27 BR00117006 PIK3CG final orf G18 A549 96 6305 Apoptosis +0.1122755596441544 1.67678898239909e-27 BR00118050 KCNK1 final orf M15 A549 96 4925 Apoptosis +0.09444459428137536 1.943806775961221e-27 BR00118050 PTK2B final orf J18 A549 96 6955 Apoptosis +0.10023753147245142 3.565792079801946e-27 BR00118050 MAPK14 final orf G22 A549 96 6110 Apoptosis +0.10439899382367189 3.827782259086709e-27 BR00118050 CTSG final orf J12 A549 96 5630 Apoptosis +0.09927125506072874 6.781996421194803e-27 BR00117006 SCNN1G final orf A04 A549 96 6175 Apoptosis +0.09768640130075361 1.0382822842205255e-26 BR00118050 ADH1C final orf M23 A549 96 6330 Apoptosis +0.08259529760959836 1.0961509916634684e-26 BR00117006 CHRM2 final orf B03 A549 96 8835 Apoptosis +0.1158873600952965 1.8749329684989114e-26 BR00117006 DYRK1B final orf G13 A549 96 4445 Apoptosis +0.11487881929019202 2.4013464797220835e-26 BR00117006 TNNC1 final orf M18 A549 96 4500 Apoptosis +0.11308108108108109 3.6645150722068527e-26 BR00118050 CHRM3 final orf A10 A549 96 4625 Apoptosis +0.07996949502384924 4.3939250044550806e-26 BR00118050 BTK final orf N01 A549 96 9210 Apoptosis +0.10303162368558962 1.1106154132423652e-25 BR00118050 CACNB4 final orf A18 A549 96 5460 Apoptosis +0.08752501667778519 2.1633874604841713e-25 BR00117006 PARP3 final orf H21 A549 96 7495 Apoptosis +0.1099792068793511 3.389343340872741e-25 BR00117006 HSP90AB1 final orf P01 A549 96 4705 Apoptosis +0.11412903994573687 3.834772023273073e-24 BR00117006 CA5A final orf B23 A549 96 4180 Apoptosis +0.12852744925831924 4.840535439127909e-24 BR00118050 DYRK1B final orf G13 A549 96 3280 Apoptosis +0.09404939595642117 5.465040262771443e-24 BR00117006 ERBB2 final orf E21 A549 96 6115 Apoptosis +0.10432400953241737 5.910248725756928e-24 BR00118050 SLC7A11 final orf G24 A549 96 4960 Apoptosis +0.08061809373929615 7.665992291050337e-24 BR00117006 JAK1 final orf H17 A549 96 8280 Apoptosis +0.09189788200984324 7.749597250882324e-24 BR00117006 ASIC1 final orf F12 A549 96 6370 Apoptosis +0.10467421817004431 1.2306953923433566e-23 BR00118050 DNMT3A final orf H07 A549 96 4855 Apoptosis +0.10034186228157227 5.197187103589206e-23 BR00117006 KCNH7 final orf A22 A549 96 5150 Apoptosis +0.09441080959570337 1.0285420740171353e-22 BR00118050 DYRK1B final orf M12 A549 96 5735 Apoptosis +0.09858600161542834 1.8198900759961354e-22 BR00117006 PLA2G1B final orf E06 A549 96 5205 Apoptosis +0.08986432561851557 1.9979893453989113e-22 BR00118050 OPRL1 final orf O16 A549 96 6265 Apoptosis +0.09260832625318606 2.2487983212731204e-22 BR00117006 BRD4 final orf F14 A549 96 5885 Apoptosis +0.07519640852974187 2.4253955121938574e-22 BR00117006 HTR3A final orf J23 A549 96 8910 Apoptosis +0.0811254837650765 5.344069813823775e-22 BR00117006 LCK final orf B18 A549 96 7535 Apoptosis +0.09179704345507002 8.0479899152701715e-22 BR00118050 IGF1R final orf N16 A549 96 5830 Apoptosis +0.08859113403352911 9.491175763577789e-22 BR00117006 ICAM1 final orf I08 A549 96 6235 Apoptosis +0.09112983140094762 1.1900820514072358e-21 BR00117006 ADRA2B final orf N18 A549 96 5860 Apoptosis +0.10188675550507671 1.2325796797558719e-21 BR00118050 MAPK8 final orf I13 A549 96 4685 Apoptosis +0.08343175034763999 5.099218435612268e-21 BR00117006 CA14 final orf N07 A549 96 6785 Apoptosis +0.09862881712550521 5.332188235005581e-21 BR00118050 PDE4D final orf B17 A549 96 4855 Apoptosis +0.07282345367287554 8.095653640517501e-21 BR00117006 PLD1 final orf L05 A549 96 8840 Apoptosis +0.14707259953161592 1.50236884416955e-20 BR00118050 ANXA1 final orf D23 A549 96 2135 Apoptosis 0.11905011179850505 1.827779318146004e-63 BR00117006 BRD4 final orf N17 A549 96 10205 Binuclear 0.12031053638921482 2.308869532423193e-58 BR00117006 PDPK1 final orf H15 A549 96 9190 Binuclear 0.11206458406458407 4.802416066970255e-53 BR00117006 HDAC3 final orf N21 A549 96 9620 Binuclear @@ -1389,6 +13809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.11675392670157068 9.360645587205051e-46 BR00118050 PTK2B final orf N19 A549 96 7640 Binuclear 0.10154525386313466 4.5789372798494235e-41 BR00117006 ASIC1 final orf L21 A549 96 9060 Binuclear 0.0938690916550769 7.759365604341062e-40 BR00118050 HDAC3 final orf N21 A549 96 10275 Binuclear +0.09673535146581484 1.8344085031954694e-39 BR00118050 S1PR1 final orf L01 A549 96 9575 Binuclear +0.0991364099721562 9.986694896153971e-39 BR00117006 PDE7A final orf J11 A549 96 8955 Binuclear +0.10363076923076923 2.1876242588257186e-38 BR00118050 HTR3A final orf J23 A549 96 8125 Binuclear +0.10360696517412936 5.680863054053866e-38 BR00118050 BRD4 final orf N17 A549 96 8040 Binuclear +0.0928894805591739 1.142785981529943e-35 BR00118050 ITGB2 final orf P21 A549 96 9380 Binuclear +0.09900770733470632 2.455665336048175e-35 BR00118050 AKR1B1 final orf L17 A549 96 8185 Binuclear +0.09437581815549215 2.8831893691093402e-34 BR00117006 PTK2B final orf N19 A549 96 8725 Binuclear +0.08393330632891155 4.9204219874348386e-33 BR00118050 TBXAS1 final orf P23 A549 96 10635 Binuclear +0.09475896689256609 7.3153281507166305e-28 BR00117006 PARP3 final orf J20 A549 96 7020 Binuclear +0.6280113367973548 2.74933252041159e-27 BR00118049 P3H1 final orf P24 A549 96 145 Binuclear +0.08346336769435692 2.5126500861316987e-26 BR00117006 CDK9 final orf H11 A549 96 8545 Binuclear +0.09362456362851876 1.9473420221236605e-25 BR00117006 PNLIP final orf L22 A549 96 6545 Binuclear +0.08089520404903552 8.2403118866571e-25 BR00117006 GAA final orf N15 A549 96 8550 Binuclear +0.08449621696614823 1.3513310439696841e-24 BR00118050 GAA final orf N15 A549 96 7775 Binuclear +0.07789393079036079 3.4185522578633473e-23 BR00117006 LPAR1 final orf B05 A549 96 8610 Binuclear +0.08165953586516589 4.615253368104181e-23 BR00117006 FPR1 final orf D21 A549 96 7805 Binuclear +0.08404773405763247 6.04305263345882e-23 BR00118050 PDPK1 final orf H15 A549 96 7325 Binuclear +0.07368936102042008 1.265511522502228e-21 BR00117006 CDK4 final orf B21 A549 96 8975 Binuclear +0.07663953608042547 3.3316057334355287e-21 BR00117006 CSF1R final orf J07 A549 96 8135 Binuclear +0.09628180039138944 4.9927301817814286e-21 BR00118050 SLC29A1 final orf L20 A549 96 5110 Binuclear +0.07157569954855005 6.635810080293821e-21 BR00117006 IMPDH1 final orf L13 A549 96 9190 Binuclear +0.07605333295159666 3.7530938511397165e-20 BR00118050 GJB4 final orf H23 A549 96 7840 Binuclear +0.0825872908101485 8.621079915784927e-20 BR00117006 S1PR2 final orf B06 A549 96 6510 Binuclear +0.08215482874937877 1.3153486487252125e-19 BR00118050 FPR1 final orf D21 A549 96 6525 Binuclear +0.07356613713223521 6.45387836119965e-19 BR00117006 CLK1 final orf J17 A549 96 7840 Binuclear +0.0828206612866259 1.856281464934354e-18 BR00117006 SIRT2 final orf A07 A549 96 6040 Binuclear +0.07381578947368421 2.0018350284680266e-18 BR00118050 JAK1 final orf H17 A549 96 7600 Binuclear +0.0950711938663746 2.2726306973453913e-18 BR00118050 PPAT final orf H14 A549 96 4565 Binuclear +0.06826376784597575 2.329984091244067e-18 BR00117006 PLD1 final orf L05 A549 96 8840 Binuclear +0.07968992248062015 3.1229563686261096e-18 BR00118050 CLK1 final orf J17 A549 96 6450 Binuclear +0.07707321968627424 3.650195453869611e-18 BR00118050 CACNA2D3 final orf L02 A549 96 6860 Binuclear +0.095435532287415 4.611756264719775e-18 BR00117006 DYRK1B final orf G13 A549 96 4445 Binuclear +0.06766129320540756 4.783119276342812e-18 BR00117006 CHRM2 final orf B03 A549 96 8835 Binuclear +0.0682868875275864 6.293080230536344e-18 BR00117006 S1PR1 final orf L01 A549 96 8615 Binuclear +0.07973808767711595 6.921915874787178e-18 BR00117006 ALK final orf H12 A549 96 6300 Binuclear +0.07121089772846961 1.0929650169623751e-17 BR00117006 GJB4 final orf H23 A549 96 7825 Binuclear +0.07631098877155659 2.6318241666086713e-17 BR00118050 PDE3A final orf O19 A549 96 6660 Binuclear +0.07903827770652447 3.883858205871795e-17 BR00118050 KCNH7 final orf A22 A549 96 6145 Binuclear +0.07960809923137575 4.1037336569965517e-17 BR00117006 ANXA1 final orf D23 A549 96 6040 Binuclear +0.08169729243686757 4.104978082722382e-17 BR00118050 DYRK1B final orf M12 A549 96 5735 Binuclear +0.07131413981744077 4.3270545052921004e-17 BR00117006 LCK final orf B18 A549 96 7535 Binuclear +0.08831570269478767 5.780772056376793e-17 BR00117006 CACNG1 final orf A16 A549 96 4860 Binuclear +0.08075807290230587 3.9698065560159896e-16 BR00118050 UGT1A9 final orf O09 A549 96 5520 Binuclear +0.08386041223045274 4.68745651125529e-16 BR00117006 CYP2A6 final orf A20 A549 96 5095 Binuclear +0.07710412777663715 9.38640490110125e-16 BR00118050 ADRA2B final orf N18 A549 96 5910 Binuclear +0.06591026000937936 1.1790832144278079e-15 BR00117006 SSTR2 final orf J01 A549 96 8045 Binuclear +0.07939443768525235 1.6960419589836435e-15 BR00118050 PPAT final orf F11 A549 96 5485 Binuclear +0.07114841662161579 2.270133680488798e-15 BR00117006 CA14 final orf N07 A549 96 6785 Binuclear +0.06487221925898162 2.3378969274560385e-15 BR00118050 GPR119 final orf N02 A549 96 8160 Binuclear +0.08563037229389138 2.7936991465377654e-15 BR00117006 UGT1A9 final orf E24 A549 96 4650 Binuclear +0.0696285506190823 6.8548811097726776e-15 BR00117006 ITGB2 final orf P21 A549 96 6865 Binuclear +0.0701500491363252 8.439277527551047e-15 BR00117006 CTSG final orf F19 A549 96 6710 Binuclear +0.06952942509149457 8.536025020002572e-15 BR00118050 PRKCE final orf J19 A549 96 6825 Binuclear +0.07780352854639465 8.679496923723896e-15 BR00117006 TNF final orf C13 A549 96 5440 Binuclear +0.06240353773268376 1.7590383289596418e-14 BR00117006 JAK1 final orf H17 A549 96 8280 Binuclear +0.0845668215839357 1.8495100288679062e-14 BR00117006 DNMT3A final orf F04 A549 96 4495 Binuclear +0.07093285770132916 1.8958541469318343e-14 BR00118050 ADA final orf P03 A549 96 6395 Binuclear +0.06768557846407225 2.7345440442639152e-14 BR00118050 PTK2B final orf J18 A549 96 6955 Binuclear +0.07151731322590264 2.7539145229176457e-14 BR00118050 PNLIP final orf L22 A549 96 6225 Binuclear +0.07936298059844996 3.0741638583591957e-14 BR00117006 GABRB2 final orf C06 A549 96 5035 Binuclear +0.05822497667401714 5.1767400231006157e-14 BR00118050 BTK final orf N01 A549 96 9210 Binuclear +0.06789667896678966 5.339517308598107e-14 BR00118050 ALK final orf J13 A549 96 6775 Binuclear +0.08172972972972974 7.421382856394197e-14 BR00118050 CHRM3 final orf A10 A549 96 4625 Binuclear +0.08082028927624924 9.43354802013975e-14 BR00118050 MAPK8 final orf I13 A549 96 4685 Binuclear +0.06149446322174125 1.3653880331082373e-13 BR00118050 CDK9 final orf N22 A549 96 7990 Binuclear +0.06485531249035377 1.873597439067121e-13 BR00118050 CA5A final orf B02 A549 96 7110 Binuclear +0.07496857741382594 2.6242761621573834e-13 BR00118050 PNLIP final orf J09 A549 96 5250 Binuclear +0.07087503874581597 3.551420495380306e-13 BR00118050 IGF1R final orf N16 A549 96 5830 Binuclear +0.062192691029900334 4.4983878550606784e-13 BR00118050 KCNQ2 final orf K01 A549 96 7525 Binuclear +0.07531219022681607 4.716730466698318e-13 BR00117006 CDK9 final orf N22 A549 96 5115 Binuclear +0.065069578248769 7.266070103608643e-13 BR00117006 CACNA2D3 final orf L02 A549 96 6750 Binuclear +0.07203791469194312 2.5310553420438183e-12 BR00118050 CDK9 final orf H11 A549 96 5275 Binuclear +0.09116616551426424 2.5473602040613343e-12 BR00118050 DYRK1B final orf G13 A549 96 3280 Binuclear +0.06455698158619227 4.260112137872398e-12 BR00118050 ATP5F1D final orf G14 A549 96 6435 Binuclear +0.0654037951529179 5.013990262968833e-12 BR00117006 KCNN1 final orf A01 A549 96 6220 Binuclear +0.06257780300650632 5.425673463565142e-12 BR00117006 FLT3 final orf E14 A549 96 6785 Binuclear +0.06286760571643696 5.715489310082402e-12 BR00117006 AKT1 final orf F15 A549 96 6710 Binuclear +0.059372915276851235 6.615674376576416e-12 BR00117006 PARP3 final orf H21 A549 96 7495 Binuclear +0.07121426908041845 8.23804846299357e-12 BR00117006 GLRA3 final orf E05 A549 96 5155 Binuclear +0.06308938912259293 8.291715643539112e-12 BR00118050 HCK final orf O01 A549 96 6555 Binuclear +0.06131937055614666 1.0710601815526299e-11 BR00118050 CDK4 final orf P20 A549 96 6880 Binuclear +0.05485269711064888 1.1281508522743478e-11 BR00117006 PTGIS final orf H13 A549 96 8580 Binuclear +0.06987117868218297 1.298253232260098e-11 BR00118050 PRKCB final orf K14 A549 96 5255 Binuclear +0.07614510408505404 1.9463748043218328e-11 BR00118050 CDK2 final orf J04 A549 96 4360 Binuclear +0.0670030439643388 2.764586788330167e-11 BR00117006 IL1B final orf G08 A549 96 5555 Binuclear +0.07712790335294872 2.8865916986783574e-11 BR00117006 CA5A final orf B23 A549 96 4180 Binuclear +0.06257070348434354 3.6744794885217287e-11 BR00118050 AVPR1A final orf D07 A549 96 6290 Binuclear +0.06368219370637655 4.754966681031468e-11 BR00118050 KCNN4 final orf A06 A549 96 6015 Binuclear +0.06866679359959381 4.85272358875504e-11 BR00118050 S1PR1 final orf P22 A549 96 5175 Binuclear +0.08274525306062491 5.023627115725855e-11 BR00118050 OPRL1 final orf A23 A549 96 3545 Binuclear 0.09455326425899682 1.2231576403763017e-37 BR00117006 GPR119 final orf N23 A549 96 9560 Elongated 0.0866542154616523 6.41068181997136e-26 BR00117006 FPR1 final orf D21 A549 96 7805 Elongated 0.07858719646799117 9.478730437522503e-25 BR00117006 ASIC1 final orf L21 A549 96 9060 Elongated @@ -1399,6 +13909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.0743188446284994 4.135618859866295e-23 BR00118050 AURKB final orf L19 A549 96 9430 Elongated 0.08638018936635106 1.0686751158461452e-22 BR00117006 CHRM3 final orf A10 A549 96 6865 Elongated 0.0859841392918156 1.256876013704787e-22 BR00118050 SLCO2B1 final orf A02 A549 96 6900 Elongated +0.07960199004975124 1.4247333766844273e-22 BR00118050 BRD4 final orf N17 A549 96 8040 Elongated +0.07823383084577114 8.114789336011974e-22 BR00117006 MAPK14 final orf G15 A549 96 8040 Elongated +0.07834635575949549 2.3154807075616034e-21 BR00118050 GJB4 final orf H23 A549 96 7840 Elongated +0.06628461760339235 6.208191281447283e-20 BR00117006 BRD4 final orf N17 A549 96 10205 Elongated +0.0727521297846275 9.303115078091033e-20 BR00118050 PDE7A final orf J11 A549 96 8380 Elongated +0.08135384243396153 9.423196379964504e-20 BR00117006 AKT1 final orf F15 A549 96 6710 Elongated +0.08394222599830077 1.8718330226379094e-18 BR00117006 SLCO2B1 final orf A02 A549 96 5885 Elongated +0.08137133466902222 7.985000704674415e-18 BR00117006 SIRT2 final orf A07 A549 96 6040 Elongated +0.0634989334989335 2.5908810056711682e-17 BR00117006 HDAC3 final orf N21 A549 96 9620 Elongated +0.08314567455180423 2.8625330805443636e-17 BR00118050 AKR1C1 final orf A24 A549 96 5590 Elongated +0.06545843025096959 3.723636891090067e-17 BR00117006 CDK4 final orf B21 A549 96 8975 Elongated +0.06806153846153846 8.77820185226173e-17 BR00118050 HTR3A final orf J23 A549 96 8125 Elongated +0.07257389410928793 1.5738234942120827e-16 BR00117006 PARP3 final orf J20 A549 96 7020 Elongated +0.07394833948339484 1.5766347511476474e-16 BR00118050 ALK final orf J13 A549 96 6775 Elongated +0.07812540824887723 2.1295581407386068e-16 BR00118050 KCNN4 final orf A06 A549 96 6015 Elongated +0.06309361123027925 2.434071210381062e-16 BR00117006 PDPK1 final orf H15 A549 96 9190 Elongated +0.0722149101426668 6.066202302625472e-16 BR00118050 ASIC1 final orf L21 A549 96 6840 Elongated +0.06585810915278396 4.184425632220415e-15 BR00118050 GAA final orf N15 A549 96 7775 Elongated +0.07125567322239032 5.178875988384527e-15 BR00117006 OPRL1 final orf A23 A549 96 6610 Elongated +0.07137315748642359 1.0749861244612064e-14 BR00117006 HSD11B1 final orf G23 A549 96 6445 Elongated +0.07982527741538058 1.3182133670090234e-14 BR00117006 CDK9 final orf N22 A549 96 5115 Elongated +0.06992683714961868 2.1930053468873866e-14 BR00117006 PNLIP final orf L22 A549 96 6545 Elongated +0.07054263565891473 2.2439998123441346e-14 BR00118050 CLK1 final orf J17 A549 96 6450 Elongated +0.05974746145848391 2.3633894510446915e-14 BR00117006 PDE7A final orf J11 A549 96 8955 Elongated +0.07410377552691776 2.396371643974153e-14 BR00118050 OPRM1 final orf A08 A549 96 5810 Elongated +0.05741605183639037 3.732222059942799e-14 BR00118050 S1PR1 final orf L01 A549 96 9575 Elongated +0.054816753095728615 7.443661389447613e-14 BR00118050 HDAC3 final orf N21 A549 96 10275 Elongated +0.07065706970048136 8.450098561872663e-14 BR00118050 KCNH7 final orf A22 A549 96 6145 Elongated +0.06785490357271835 9.548280794788714e-14 BR00118050 ABL1 final orf M24 A549 96 6640 Elongated +0.07499838417213148 1.9664191909675105e-13 BR00118050 PORCN final orf D22 A549 96 5305 Elongated +0.06027275735305641 2.3540254242935505e-13 BR00118050 AKR1B1 final orf L17 A549 96 8185 Elongated +0.08035003883137766 2.5987002522691173e-13 BR00118050 HSP90AB1 final orf P01 A549 96 4585 Elongated +0.07760697303180963 3.3549303707880836e-13 BR00117006 CACNG1 final orf A16 A549 96 4860 Elongated +0.05759093813466235 3.415905627777437e-13 BR00117006 CHRM2 final orf B03 A549 96 8835 Elongated +0.07097747135751502 3.6995190050198785e-13 BR00118050 MMP2 final orf F06 A549 96 5810 Elongated +0.06510032055979587 4.91964009326377e-13 BR00118050 PRKCE final orf J19 A549 96 6825 Elongated +0.06046770377767718 5.970463583660245e-13 BR00117006 P2RY12 final orf B01 A549 96 7860 Elongated +0.0704152249134948 7.004211366933128e-13 BR00117006 PTGIS final orf F16 A549 96 5780 Elongated +0.06135956917389819 7.102792622310605e-13 BR00117006 TUBB4B final orf E07 A549 96 7595 Elongated +0.06723366199996368 1.8461459456849657e-12 BR00117006 HDAC3 final orf N06 A549 96 6120 Elongated +0.06799335964067428 2.305466097444682e-12 BR00117006 HPGDS final orf O21 A549 96 5920 Elongated +0.0579254502938143 2.9612468717672654e-12 BR00118050 ALDH2 final orf P13 A549 96 8095 Elongated +0.06596968781778086 3.285553922499134e-12 BR00118050 PLK1 final orf N08 A549 96 6215 Elongated +0.06097463641460151 4.187583879709273e-12 BR00117006 TUBB3 final orf K05 A549 96 7220 Elongated +0.053333557711200213 4.846217599584629e-12 BR00118050 ITGB2 final orf P21 A549 96 9380 Elongated +0.05983094198541236 7.584940095892825e-12 BR00117006 AGER final orf H09 A549 96 7315 Elongated +0.06630260136846862 8.932568904147949e-12 BR00118050 FFAR2 final orf B15 A549 96 5920 Elongated +0.06312004991064725 9.377442027071131e-12 BR00118050 FPR1 final orf D21 A549 96 6525 Elongated +0.0795593635250918 1.1509846729465225e-11 BR00118050 ADORA2A final orf O18 A549 96 4085 Elongated +0.06251896813353566 1.2826400503782573e-11 BR00117006 PTGIR final orf E16 A549 96 6590 Elongated +0.058823529411764705 1.522423852869454e-11 BR00117006 ATP5F1D final orf G14 A549 96 7395 Elongated +0.0720081135902637 1.5514109056234953e-11 BR00118050 GHSR final orf A17 A549 96 4930 Elongated +0.06289429666582445 1.962637618473618e-11 BR00117006 KRAS final orf D17 A549 96 6390 Elongated +0.06787076632185297 3.565918185632714e-11 BR00117006 P3H1 final orf P24 A549 96 5355 Elongated +0.062089300923738294 3.7395429651995636e-11 BR00117006 CHRM3 final orf A11 A549 96 6380 Elongated +0.0635322665368263 4.610465175304173e-11 BR00117006 ANXA1 final orf D23 A549 96 6040 Elongated +0.06181537155294061 5.448875024059154e-11 BR00118050 GHSR final orf C24 A549 96 6335 Elongated +0.06288006279941287 6.237968266701322e-11 BR00118050 P3H1 final orf P24 A549 96 6100 Elongated +0.059101765380719595 7.592729714085078e-11 BR00117006 PAK4 final orf G10 A549 96 6860 Elongated +0.06742640075973409 7.919428170685549e-11 BR00118050 KCNH7 final orf O07 A549 96 5265 Elongated +0.265334196471921 8.080082163292825e-11 BR00118049 PDPK1 final orf H15 A549 96 334 Elongated +0.05958273485372986 9.637090661088533e-11 BR00117006 CYP2A6 final orf A15 A549 96 6670 Elongated +0.052635574924624694 1.1591327453407025e-10 BR00117006 AURKB final orf L19 A549 96 8490 Elongated +0.056449687369036716 1.8634665108956871e-10 BR00118050 HSD11B1 final orf C02 A549 96 7235 Elongated +0.07308700045064252 2.5057616574143254e-10 BR00118050 KCNN1 final orf A01 A549 96 4260 Elongated +0.2758829559220949 2.7726814566788173e-10 BR00118049 PRKCE final orf J19 A549 96 294 Elongated +0.059468230394210335 3.0410851026572916e-10 BR00117006 ASIC1 final orf F12 A549 96 6370 Elongated +0.05754151565712725 3.2526065681397895e-10 BR00117006 FLT3 final orf E14 A549 96 6785 Elongated +0.06201631977381392 3.385798887885956e-10 BR00118050 HTR3A final orf H24 A549 96 5825 Elongated +0.05869067139685952 3.560776527867459e-10 BR00118050 RPL23A final orf G16 A549 96 6485 Elongated +0.06709033666291389 5.829872699300642e-10 BR00118050 TGFBR1 final orf I23 A549 96 4865 Elongated +0.0505038851459838 6.272624754602026e-10 BR00117006 CDK9 final orf H11 A549 96 8545 Elongated +0.06390977443609022 7.220359732094532e-10 BR00118050 CYP1A2 final orf N12 A549 96 5320 Elongated +0.058933645039026095 7.453917844793973e-10 BR00117006 KCNN1 final orf A01 A549 96 6220 Elongated +0.061416270092410706 7.597770463597155e-10 BR00118050 CA14 final orf N07 A549 96 5730 Elongated +0.0618146874495398 8.293633020540862e-10 BR00118050 CTSG final orf J12 A549 96 5630 Elongated +0.060489960553755384 1.3138822687157181e-09 BR00117006 BRAF final orf I10 A549 96 5765 Elongated +0.05263657137252294 1.5066517367654648e-09 BR00118050 SSTR2 final orf J01 A549 96 7570 Elongated +0.048456550739143164 1.5836794744931665e-09 BR00117006 HTR3A final orf J23 A549 96 8910 Elongated +0.05758988780385499 1.7646132907143668e-09 BR00118050 BAX final orf G12 A549 96 6260 Elongated +0.060864539344277574 2.7563707190065374e-09 BR00118050 HRH4 final orf O05 A549 96 5480 Elongated +0.056495928358796466 2.7811212740367556e-09 BR00117006 CSK final orf P05 A549 96 6375 Elongated +0.05262116227405742 2.9634170916295377e-09 BR00117006 ALDH2 final orf P14 A549 96 7325 Elongated +0.05573518090839107 3.4259341436607017e-09 BR00117006 P3H1 final orf F23 A549 96 6495 Elongated +0.057154660146761245 3.558100884417875e-09 BR00118050 CACNA2D3 final orf P19 A549 96 6155 Elongated +0.05249795474385166 4.01665670804445e-09 BR00117006 AURKB final orf H10 A549 96 7245 Elongated +0.06406331269996461 4.039133674131791e-09 BR00118050 PDE4D final orf B17 A549 96 4855 Elongated +0.0637948717948718 4.7815620178378955e-09 BR00117006 AKT1 final orf J16 A549 96 4875 Elongated +0.061663826307740574 5.080348821313876e-09 BR00118050 MME final orf I11 A549 96 5185 Elongated +0.06453955120836857 5.489855152370066e-09 BR00117006 HSP90AB1 final orf P01 A549 96 4705 Elongated 0.1608586550236988 2.122948251265063e-108 BR00117006 GPR119 final orf N23 A549 96 9560 Grape 0.1586092715231788 7.984411108883657e-100 BR00117006 ASIC1 final orf L21 A549 96 9060 Grape 0.1618873442271436 2.4352772799180294e-96 BR00118050 PDE7A final orf J11 A549 96 8380 Grape @@ -1409,6 +14009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.14344106824155572 4.353682147236825e-85 BR00118050 AURKB final orf L19 A549 96 9430 Grape 0.1537313432835821 2.8637324429046993e-83 BR00118050 BRD4 final orf N17 A549 96 8040 Grape 0.14145372661660657 1.1497682717843716e-80 BR00117006 PDPK1 final orf H15 A549 96 9190 Grape +0.1381936086016508 3.511090171224342e-80 BR00118050 S1PR1 final orf L01 A549 96 9575 Grape +0.13579290979290978 8.342901643201069e-78 BR00117006 HDAC3 final orf N21 A549 96 9620 Grape +0.14258834685661162 1.032445808636883e-75 BR00117006 AURKB final orf L19 A549 96 8490 Grape +0.13569122634026357 1.0628932929181736e-75 BR00118050 ITGB2 final orf P21 A549 96 9380 Grape +0.1379368379855949 8.451541897109492e-73 BR00117006 PTK2B final orf N19 A549 96 8725 Grape +0.14042591900798793 9.136994181371002e-71 BR00118050 AKR1B1 final orf L17 A549 96 8185 Grape +0.13018480815375302 1.5019872824094902e-66 BR00117006 PDE7A final orf J11 A549 96 8955 Grape +0.1300604705995448 2.1836150416404316e-63 BR00117006 CDK9 final orf H11 A549 96 8545 Grape +0.11364869263317778 2.806628090420596e-60 BR00118050 TBXAS1 final orf P23 A549 96 10635 Grape +0.12191392099468852 1.5241077705267486e-58 BR00117006 CDK4 final orf B21 A549 96 8975 Grape +0.12720898833299296 2.9889852116189785e-55 BR00118050 GAA final orf N15 A549 96 7775 Grape +0.12505880588429735 6.777287551490359e-54 BR00118050 GJB4 final orf H23 A549 96 7840 Grape +0.12761626431017914 2.1289365404745356e-52 BR00118050 PDPK1 final orf H15 A549 96 7325 Grape +0.12042278993018275 7.685878839767655e-50 BR00117006 GJB4 final orf H23 A549 96 7825 Grape +0.1147050685282088 8.143114503889047e-50 BR00117006 LPAR1 final orf B05 A549 96 8610 Grape +0.11856818406658493 1.8269110082663212e-48 BR00117006 CLK1 final orf J17 A549 96 7840 Grape +0.11540278849985966 1.9251769995267315e-48 BR00117006 JAK1 final orf H17 A549 96 8280 Grape +0.11611335656674139 2.1282577584420298e-48 BR00118050 GPR119 final orf N02 A549 96 8160 Grape +0.11020938819921008 1.5777190601664104e-47 BR00117006 HTR3A final orf J23 A549 96 8910 Grape +0.1454173183497448 2.1220097583478073e-47 BR00117006 CYP2A6 final orf A20 A549 96 5095 Grape +0.10996761111920438 5.723881267596937e-47 BR00117006 CHRM2 final orf B03 A549 96 8835 Grape +0.13135089209855566 1.2060572915508756e-44 BR00117006 GHSR final orf C24 A549 96 5885 Grape +0.10638719073192789 1.3099802313911777e-42 BR00117006 GAA final orf N15 A549 96 8550 Grape +0.11101424469719985 2.3650347705137633e-42 BR00117006 FPR1 final orf D21 A549 96 7805 Grape +0.12065227847084599 5.4333490116742415e-42 BR00117006 PNLIP final orf L22 A549 96 6545 Grape +0.1078723785928053 1.2054462651825727e-41 BR00117006 CSF1R final orf J07 A549 96 8135 Grape +0.13431200199556997 4.998367155231707e-40 BR00117006 GABRB2 final orf C06 A549 96 5035 Grape +0.12040253589091177 1.0069011037658302e-39 BR00118050 PNLIP final orf L22 A549 96 6225 Grape +0.09833786487942868 4.215377424824523e-39 BR00117006 IMPDH1 final orf L13 A549 96 9190 Grape +0.11270160673037342 2.2847574814345926e-38 BR00118050 CACNA2D3 final orf L02 A549 96 6860 Grape +0.14673326500623587 2.791515601586043e-38 BR00118050 CSF1R final orf D14 A549 96 4025 Grape +0.10859069109318362 1.8460821842964457e-36 BR00117006 PARP3 final orf J20 A549 96 7020 Grape +0.11965689589052156 1.5258437241800557e-35 BR00118050 CTSG final orf J12 A549 96 5630 Grape +0.11512270133755315 2.772103993614952e-35 BR00117006 SIRT2 final orf A07 A549 96 6040 Grape +0.1150252388174438 2.77210401812186e-35 BR00117006 ANXA1 final orf D23 A549 96 6040 Grape +0.09897333940879569 6.048757513839388e-35 BR00118050 ALDH2 final orf P13 A549 96 8095 Grape +0.1195036711124416 7.866523421986349e-35 BR00118050 UGT1A9 final orf O09 A549 96 5520 Grape +0.09204137617465195 2.0482922768817884e-34 BR00118050 BTK final orf N01 A549 96 9210 Grape +0.09733759352986708 1.3069656640275451e-33 BR00117006 SSTR2 final orf J01 A549 96 8045 Grape +0.10602593520780242 2.122941831019873e-32 BR00118050 FPR1 final orf D21 A549 96 6525 Grape +0.10391143911439114 2.9904558849225854e-32 BR00118050 ALK final orf J13 A549 96 6775 Grape +0.1116894132335371 9.761585960562502e-32 BR00117006 BRAF final orf I10 A549 96 5765 Grape +0.09760554778338032 1.0724062261562394e-31 BR00117006 LCK final orf B18 A549 96 7535 Grape +0.11839530332681017 1.3269671518389017e-31 BR00118050 SLC29A1 final orf L20 A549 96 5110 Grape +0.10962995881400353 3.7999106192120295e-31 BR00117006 PORCN final orf D22 A549 96 5870 Grape +0.10850703844859529 1.7527026842111777e-30 BR00117006 ADRA2B final orf N18 A549 96 5860 Grape +0.08811997736688032 1.452174084441054e-29 BR00117006 S1PR1 final orf L01 A549 96 8615 Grape +0.08823018994287782 1.680793574127717e-29 BR00117006 PTGIS final orf H13 A549 96 8580 Grape +0.09949949829661185 2.4521075392749326e-29 BR00118050 P3H1 final orf F23 A549 96 6705 Grape +0.13125975989622493 4.1566300692794716e-29 BR00117006 P2RY12 final orf B24 A549 96 3810 Grape +0.09312875250166777 1.0743604289939078e-28 BR00117006 PARP3 final orf H21 A549 96 7495 Grape +0.09982891803495388 1.4948689173732522e-28 BR00118050 SCNN1G final orf O03 A549 96 6485 Grape +0.1339640690815677 3.7364190955207056e-28 BR00118050 OPRL1 final orf A23 A549 96 3545 Grape +0.09647813713473981 4.182181528129967e-28 BR00118050 PRKCE final orf J19 A549 96 6825 Grape +0.11380564485139648 6.675051663219827e-28 BR00117006 CACNG1 final orf A16 A549 96 4860 Grape +0.09432152132639371 2.110771709293779e-27 BR00118050 PTK2B final orf J18 A549 96 6955 Grape +0.09350087931422296 2.490749812628306e-27 BR00117006 FOXM1 final orf J02 A549 96 7070 Grape +0.08520004510409458 5.604412500897476e-27 BR00118050 ANXA1 final orf N24 A549 96 8395 Grape +0.11200265810204814 5.921341963806382e-27 BR00118050 DNMT3A final orf H07 A549 96 4855 Grape +0.0986347995169166 7.064380544545496e-27 BR00117006 ICAM1 final orf I08 A549 96 6235 Grape +0.09739045789631151 1.3352513576695419e-26 BR00118050 ADH1C final orf M23 A549 96 6330 Grape +0.106311361070393 4.838378008512014e-26 BR00117006 PLA2G1B final orf E06 A549 96 5205 Grape +0.11330914655214966 1.2717055808645643e-25 BR00117006 TNNC1 final orf M18 A549 96 4500 Grape +0.09485578360036859 2.732975611399651e-25 BR00117006 MAPK8 final orf I14 A549 96 6350 Grape +0.08592105263157895 8.0509781051743755e-25 BR00118050 JAK1 final orf H17 A549 96 7600 Grape +0.09079812407416797 8.121024387003106e-25 BR00117006 CA14 final orf N07 A549 96 6785 Grape +0.10593313327828026 1.1252211080330085e-24 BR00118050 SLC7A11 final orf G24 A549 96 4960 Grape +0.09997013750366392 1.350467938304543e-24 BR00117006 IL1B final orf G08 A549 96 5555 Grape +0.08833433456251034 1.4156260049324287e-24 BR00118050 CA5A final orf B02 A549 96 7110 Grape +0.10855956563398275 2.6732738810260378e-24 BR00117006 UGT1A9 final orf E24 A549 96 4650 Grape +0.09296431453942582 3.456501428626584e-24 BR00117006 PIK3CG final orf G18 A549 96 6305 Grape +0.09178294573643411 4.699090351481945e-24 BR00118050 CLK1 final orf J17 A549 96 6450 Grape +0.11158098157143959 7.203464695083977e-24 BR00118050 FLT3 final orf K13 A549 96 4320 Grape +0.10767567567567568 9.34118276635081e-24 BR00118050 CHRM3 final orf A10 A549 96 4625 Grape +0.0770290090180453 2.9001866212169184e-23 BR00117006 PLD1 final orf L05 A549 96 8840 Grape +0.08949973320646186 3.619591138128612e-23 BR00117006 S1PR2 final orf B06 A549 96 6510 Grape +0.08757027711759194 7.73417487103338e-23 BR00118050 GJB4 final orf P08 A549 96 6715 Grape +0.0823920265780731 1.2366611415552026e-22 BR00118050 KCNQ2 final orf K01 A549 96 7525 Grape +0.10155646357285326 1.4757406627716187e-22 BR00118050 KCNK1 final orf M15 A549 96 4925 Grape +0.09579202351822207 2.435787477680113e-22 BR00118050 PPAT final orf F11 A549 96 5485 Grape +0.09113932835188486 3.297576304070389e-22 BR00118050 KCNN4 final orf A06 A549 96 6015 Grape +0.08858668088177388 3.4898455465195625e-22 BR00117006 ASIC1 final orf F12 A549 96 6370 Grape +0.09273356401384084 4.843612130268916e-22 BR00117006 PTGIS final orf F16 A549 96 5780 Grape +0.08906624102154828 4.899439102788759e-22 BR00118050 OPRL1 final orf O16 A549 96 6265 Grape +0.08035484319574693 6.133945685593749e-22 BR00117006 BTK final orf N01 A549 96 7655 Grape +0.10071794871794872 6.163558677451374e-22 BR00117006 AKT1 final orf J16 A549 96 4875 Grape +0.08787466140186971 6.488575477714746e-22 BR00117006 KRAS final orf D17 A549 96 6390 Grape +0.08840233710951327 7.609945945285335e-22 BR00118050 F10 final orf C09 A549 96 6285 Grape +0.08855353874305823 8.801357657921427e-22 BR00118050 ALDH2 final orf P14 A549 96 6260 Grape +0.08516779899784233 1.3724476043660584e-21 BR00117006 ERBB2 final orf I20 A549 96 6700 Grape 0.16567164179104477 1.061704730795507e-96 BR00118050 BRD4 final orf N17 A549 96 8040 Hole 0.15042219467727122 9.099858260892933e-95 BR00117006 GPR119 final orf N23 A549 96 9560 Hole 0.15065235452419598 2.732248630874925e-89 BR00117006 CDK4 final orf B21 A549 96 8975 Hole @@ -1419,6 +14109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.1322046658472367 2.6170733103945475e-72 BR00118050 AURKB final orf L19 A549 96 9430 Hole 0.12924005945407047 1.0677540000687512e-68 BR00118050 ITGB2 final orf P21 A549 96 9380 Hole 0.12203669841693982 4.057156416726301e-67 BR00118050 HDAC3 final orf N21 A549 96 10275 Hole +0.1405759162303665 3.300167295543445e-66 BR00118050 PTK2B final orf N19 A549 96 7640 Hole +0.12615894039735098 3.2523868780072217e-63 BR00117006 ASIC1 final orf L21 A549 96 9060 Hole +0.11591131077756034 3.558150302600294e-60 BR00117006 BRD4 final orf N17 A549 96 10205 Hole +0.11559819254922167 3.0185341081270376e-49 BR00118050 PDE7A final orf J11 A549 96 8380 Hole +0.10730320453603873 1.876550976469391e-48 BR00118050 S1PR1 final orf L01 A549 96 9575 Hole +0.11353849075051071 4.4846351072264227e-48 BR00117006 AURKB final orf L19 A549 96 8490 Hole +0.11736645849135632 2.340473405607978e-47 BR00117006 GJB4 final orf H23 A549 96 7825 Hole +0.10907316601918374 3.032853176678722e-46 BR00117006 ALDH2 final orf P13 A549 96 8835 Hole +0.11157173301676761 8.642545420472801e-45 BR00118050 AKR1B1 final orf L17 A549 96 8185 Hole +0.1267820151356141 8.75537467512435e-43 BR00117006 ANXA1 final orf D23 A549 96 6040 Hole +0.11640987330904595 5.487537128460226e-40 BR00118050 P3H1 final orf F23 A549 96 6705 Hole +0.10276705527612066 8.727693152004441e-40 BR00117006 GAA final orf N15 A549 96 8550 Hole +0.10752836686837093 1.0353301671458469e-39 BR00117006 FPR1 final orf D21 A549 96 7805 Hole +0.11512915129151291 1.6494785259053243e-39 BR00118050 ALK final orf J13 A549 96 6775 Hole +0.09117644224082233 6.493006788646944e-39 BR00118050 TBXAS1 final orf P23 A549 96 10635 Hole +0.09820734290611248 1.4558361172754905e-37 BR00117006 CHRM2 final orf B03 A549 96 8835 Hole +0.09880628114234508 9.979502165178196e-37 BR00117006 CDK9 final orf H11 A549 96 8545 Hole +0.09857714180405167 5.9462707263245195e-36 BR00118050 ANXA1 final orf N24 A549 96 8395 Hole +0.10150833540722906 2.6341426455032704e-35 BR00118050 GAA final orf N15 A549 96 7775 Hole +0.1006720951357204 5.233446529623064e-35 BR00118050 GJB4 final orf H23 A549 96 7840 Hole +0.10236130893762582 8.693639523153452e-35 BR00117006 LCK final orf B18 A549 96 7535 Hole +0.10108632802959207 1.7709426871910462e-34 BR00117006 BTK final orf N01 A549 96 7655 Hole +0.09134557561052759 8.22645256717384e-34 BR00117006 PDPK1 final orf H15 A549 96 9190 Hole +0.09130130320820337 9.071628358799755e-33 BR00117006 HTR3A final orf J23 A549 96 8910 Hole +0.10068841644653395 9.14728952108064e-33 BR00118050 PDPK1 final orf H15 A549 96 7325 Hole +0.676570618800189 5.098227830717388e-32 BR00118049 P3H1 final orf P24 A549 96 145 Hole +0.08841803699254962 6.937965273404599e-31 BR00117006 PDE7A final orf J11 A549 96 8955 Hole +0.08893260422573195 4.233872575958615e-30 BR00117006 LPAR1 final orf B05 A549 96 8610 Hole +0.0913942628418946 1.1907938385867187e-27 BR00117006 PARP3 final orf H21 A549 96 7495 Hole +0.09844961240310078 1.2852201466277669e-27 BR00118050 CLK1 final orf J17 A549 96 6450 Hole +0.0872494657329316 2.0745077371655807e-27 BR00117006 CSF1R final orf J07 A549 96 8135 Hole +0.09880680570937453 2.1222921889148005e-27 BR00117006 MAPK8 final orf I14 A549 96 6350 Hole +0.09452793530178845 5.331442277711051e-27 BR00118050 PRKCE final orf J19 A549 96 6825 Hole +0.08248103681089451 6.117163454957996e-26 BR00117006 S1PR1 final orf L01 A549 96 8615 Hole +0.09840218849993382 1.9487175544454945e-25 BR00117006 RPL23A final orf G16 A549 96 5920 Hole +0.09382285244988668 1.9527773883885218e-25 BR00118050 FPR1 final orf D21 A549 96 6525 Hole +0.08051451988705491 8.05691392401583e-24 BR00117006 JAK1 final orf H17 A549 96 8280 Hole +0.0916229892216601 8.609265573267447e-24 BR00117006 KRAS final orf D17 A549 96 6390 Hole +0.08817726533355912 1.3549310713251596e-23 BR00118050 ASIC1 final orf L21 A549 96 6840 Hole +0.08024240743913214 5.589498554457381e-23 BR00117006 SSTR2 final orf J01 A549 96 8045 Hole +0.07966837710974171 4.103597738266208e-22 BR00117006 CLK1 final orf J17 A549 96 7840 Hole +0.08450528643890902 2.024634060634701e-21 BR00117006 CYP3A4 final orf K22 A549 96 6755 Hole +0.0841667156173008 2.2040034702874255e-21 BR00117006 FLT3 final orf E14 A549 96 6785 Hole +0.07661691542288557 6.098692713291225e-21 BR00117006 DNMT3A final orf H07 A549 96 8040 Hole +0.09190647482014389 7.546817604476362e-21 BR00118050 BTK final orf P10 A549 96 5560 Hole +0.09108444009365413 9.247971642713767e-21 BR00118050 CTSG final orf J12 A549 96 5630 Hole +0.09530332681017613 1.3049636705703306e-20 BR00118050 SLC29A1 final orf L20 A549 96 5110 Hole +0.10683208960918067 1.4541651251893116e-20 BR00117006 MMP2 final orf F06 A549 96 4050 Hole +0.07673785979030534 2.42815288444944e-20 BR00117006 FLT3 final orf K13 A549 96 7765 Hole +0.08915440673898581 2.7032117476796584e-20 BR00118050 DYRK1B final orf M12 A549 96 5735 Hole +0.08375673595073133 3.0996259394934835e-20 BR00117006 P3H1 final orf F23 A549 96 6495 Hole +0.0843002047202276 3.7859699452965675e-20 BR00117006 ASIC1 final orf F12 A549 96 6370 Hole +0.08473916577749678 5.194265018895165e-20 BR00117006 AVPR1A final orf D07 A549 96 6260 Hole +0.07064877523051745 1.2518882071213978e-19 BR00117006 PLD1 final orf L05 A549 96 8840 Hole +0.09018805747299338 1.962954913676237e-19 BR00117006 AKR1C1 final orf A24 A549 96 5360 Hole +0.09233562388749153 2.09818944911828e-19 BR00117006 CDK9 final orf N22 A549 96 5115 Hole +0.08020756115641216 2.7361572830385635e-19 BR00117006 CYP1A2 final orf F21 A549 96 6745 Hole +0.09015444015444016 9.845370190385157e-19 BR00117006 KCNH7 final orf O07 A549 96 5180 Hole +0.07157020140552592 1.3955279408489938e-18 BR00117006 AKR1B1 final orf L17 A549 96 8150 Hole +0.11181776907790439 2.5404833025274537e-18 BR00118050 DYRK1B final orf G13 A549 96 3280 Hole +0.08161096669161186 5.7883425212959845e-18 BR00118050 CLK1 final orf D08 A549 96 6045 Hole +0.08275276125743415 6.027888073581134e-18 BR00117006 BRD4 final orf F14 A549 96 5885 Hole +0.08493238771989255 8.657452973988837e-18 BR00118050 UGT1A9 final orf O09 A549 96 5520 Hole +0.07690606416624164 1.1279712265610677e-17 BR00117006 RPL23A final orf I07 A549 96 6690 Hole +0.09372428666558029 1.749119591183341e-17 BR00118050 LCK final orf B18 A549 96 4460 Hole +0.07064226908401279 6.100442105952657e-17 BR00117006 TUBB4B final orf E07 A549 96 7595 Hole +0.08757984971649097 7.16729499159148e-17 BR00118050 KCNK1 final orf M15 A549 96 4925 Hole +0.06752450980392156 1.3531877988838168e-16 BR00117006 F10 final orf C09 A549 96 8160 Hole +0.077724646311119 2.695229402753231e-16 BR00117006 SIRT2 final orf A07 A549 96 6040 Hole +0.07331560450641274 3.369406775032271e-16 BR00117006 S100B final orf I09 A549 96 6735 Hole +0.07903350304654555 4.158470150202018e-16 BR00117006 BRAF final orf I10 A549 96 5765 Hole +0.0848299473139011 7.868303742542177e-16 BR00118050 TGFBR1 final orf O14 A549 96 4920 Hole +0.07469410476185061 1.446128021724445e-15 BR00117006 KCNN1 final orf A01 A549 96 6220 Hole +0.08082706766917293 1.555223199316716e-15 BR00118050 CYP1A2 final orf N12 A549 96 5320 Hole +0.06122403161373374 1.8569674965390782e-15 BR00118050 BTK final orf N01 A549 96 9210 Hole +0.07628131872980286 2.536290895403091e-15 BR00117006 PORCN final orf D22 A549 96 5870 Hole +0.07684005176211618 2.6780333920029632e-15 BR00118050 SLC29A1 final orf N03 A549 96 5775 Hole +0.07045634685592397 3.1250376428812778e-15 BR00117006 PRKCB final orf K19 A549 96 6855 Hole +0.07337663092098384 4.962809161286487e-15 BR00118050 PNLIP final orf L22 A549 96 6225 Hole +0.06693711967545639 7.968585142553538e-15 BR00117006 ATP5F1D final orf G14 A549 96 7395 Hole +0.0711760184473482 9.50753931777611e-15 BR00117006 TUBB3 final orf G06 A549 96 6505 Hole +0.0707434668630767 1.995464513536349e-14 BR00117006 KCNN4 final orf A06 A549 96 6425 Hole +0.07111404105580107 2.5478858471512314e-14 BR00117006 PIK3CG final orf G18 A549 96 6305 Hole +0.06447368421052632 3.7336716582513686e-14 BR00118050 JAK1 final orf H17 A549 96 7600 Hole +0.08041025641025641 3.965789907275394e-14 BR00117006 AKT1 final orf J16 A549 96 4875 Hole +0.06955365292235693 4.2437564242667205e-14 BR00117006 ELANE final orf D19 A549 96 6480 Hole +0.06684484600735847 4.527076397290667e-14 BR00117006 PARP3 final orf J20 A549 96 7020 Hole +0.06511965902003686 5.917686993430975e-14 BR00117006 ALDH2 final orf P14 A549 96 7325 Hole +0.05775756181038345 9.236177522161592e-14 BR00117006 IMPDH1 final orf L13 A549 96 9190 Hole +0.06853582554517133 1.567829117132988e-13 BR00117006 CDK2 final orf L03 A549 96 6420 Hole 0.17759062670500014 3.753751519699841e-132 BR00117006 GPR119 final orf N23 A549 96 9560 Interphase 0.155007946451647 3.1078592734245666e-108 BR00118050 HDAC3 final orf N21 A549 96 10275 Interphase 0.1638153846153846 1.5345542993433277e-95 BR00118050 HTR3A final orf J23 A549 96 8125 Interphase @@ -1429,6 +14209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.13935393824749853 6.769370735359737e-87 BR00117006 BRD4 final orf N17 A549 96 10205 Interphase 0.14333034533034533 1.31493796750466e-86 BR00117006 HDAC3 final orf N21 A549 96 9620 Interphase 0.14952443147324954 1.687845655763206e-85 BR00117006 PTK2B final orf N19 A549 96 8725 Interphase +0.14503386111403113 9.585874617799567e-85 BR00117006 PDPK1 final orf H15 A549 96 9190 Interphase +0.15067800766833553 1.7758075192011734e-83 BR00118050 PDE7A final orf J11 A549 96 8380 Interphase +0.14164450725604452 1.020576413468653e-74 BR00117006 AURKB final orf L19 A549 96 8490 Interphase +0.13238164664564595 5.504833703152234e-69 BR00117006 CDK4 final orf B21 A549 96 8975 Interphase +0.1283488396632149 9.715532103793068e-68 BR00118050 ITGB2 final orf P21 A549 96 9380 Interphase +0.1265197838023008 3.1004055584905735e-67 BR00118050 S1PR1 final orf L01 A549 96 9575 Interphase +0.13995746959869074 4.746919944831676e-67 BR00117006 FPR1 final orf D21 A549 96 7805 Interphase +0.1340037321855113 2.6734306897195203e-61 BR00118050 GAA final orf N15 A549 96 7775 Interphase +0.13077208845096505 1.003524550276659e-58 BR00117006 GJB4 final orf H23 A549 96 7825 Interphase +0.1326731603294375 1.2648349101177137e-56 BR00118050 PDPK1 final orf H15 A549 96 7325 Interphase +0.12245443616530484 3.199746308910956e-56 BR00117006 CDK9 final orf H11 A549 96 8545 Interphase +0.12146607208941369 2.3162564069363694e-55 BR00117006 GAA final orf N15 A549 96 8550 Interphase +0.11856131039128756 3.0442236189013497e-55 BR00117006 PDE7A final orf J11 A549 96 8955 Interphase +0.12332899667340325 1.0805333325342763e-54 BR00118050 AKR1B1 final orf L17 A549 96 8185 Interphase +0.13759687026622164 1.8301728772468025e-54 BR00117006 PNLIP final orf L22 A549 96 6545 Interphase +0.11779730497964147 7.179570533177724e-54 BR00117006 CHRM2 final orf B03 A549 96 8835 Interphase +0.13195571955719557 8.357703942174698e-52 BR00118050 ALK final orf J13 A549 96 6775 Interphase +0.13804489910504458 1.1692972145838618e-50 BR00117006 ANXA1 final orf D23 A549 96 6040 Interphase +0.11494048647736366 5.072161880459562e-50 BR00117006 LPAR1 final orf B05 A549 96 8610 Interphase +0.11802658188642119 5.59683519946516e-48 BR00118050 GJB4 final orf H23 A549 96 7840 Interphase +0.11829676301815871 2.4558363322802194e-46 BR00117006 LCK final orf B18 A549 96 7535 Interphase +0.1263565891472868 2.8895673675426065e-45 BR00118050 CLK1 final orf J17 A549 96 6450 Interphase +0.13213233392441387 3.711657951323533e-45 BR00117006 PORCN final orf D22 A549 96 5870 Interphase +0.10546261107463573 4.891103086699058e-45 BR00118050 BTK final orf N01 A549 96 9210 Interphase +0.10912037447735072 1.181094626132975e-42 BR00117006 CSF1R final orf J07 A549 96 8135 Interphase +0.10002673544807957 2.845740964219294e-39 BR00117006 HTR3A final orf J23 A549 96 8910 Interphase +0.10645083712780941 3.864529146386532e-39 BR00117006 CLK1 final orf J17 A549 96 7840 Interphase +0.11244593447983278 4.5871015699600423e-39 BR00117006 PARP3 final orf J20 A549 96 7020 Interphase +0.09991557801512625 7.360677824871093e-39 BR00117006 ALDH2 final orf P13 A549 96 8835 Interphase +0.11476734800339787 6.744554638822154e-38 BR00118050 FPR1 final orf D21 A549 96 6525 Interphase +0.11306184604148349 8.934711574039086e-38 BR00118050 P3H1 final orf F23 A549 96 6705 Interphase +0.08911658137814332 3.4224994976735827e-37 BR00118050 TBXAS1 final orf P23 A549 96 10635 Interphase +0.09982878221073865 2.207006069184485e-36 BR00117006 JAK1 final orf H17 A549 96 8280 Interphase +0.10393595730486992 1.1930778502855985e-35 BR00117006 PARP3 final orf H21 A549 96 7495 Interphase +0.10689939604788515 1.6842952800231558e-34 BR00118050 ASIC1 final orf L21 A549 96 6840 Interphase +0.11497025441817083 3.681511225553835e-34 BR00117006 ADRA2B final orf N18 A549 96 5860 Interphase +0.11418861512319456 8.046355238631041e-34 BR00117006 GHSR final orf C24 A549 96 5885 Interphase +0.09725183976217219 9.318700785130689e-34 BR00118050 ALDH2 final orf P13 A549 96 8095 Interphase +0.10840208124004772 4.018518879998739e-33 BR00117006 KRAS final orf D17 A549 96 6390 Interphase +0.09233717148941196 2.051750760917507e-32 BR00117006 S1PR1 final orf L01 A549 96 8615 Interphase +0.12264550990041186 2.4149023332761534e-32 BR00117006 CACNG1 final orf A16 A549 96 4860 Interphase +0.10333761211674153 3.361232347125442e-32 BR00118050 PRKCE final orf J19 A549 96 6825 Interphase +0.1042225682185982 3.493036638764939e-32 BR00117006 AKT1 final orf F15 A549 96 6710 Interphase +0.10303120247932479 3.9179406266522325e-32 BR00118050 CACNA2D3 final orf L02 A549 96 6860 Interphase +0.10865051903114187 4.092788614621263e-30 BR00117006 PTGIS final orf F16 A549 96 5780 Interphase +0.11506849315068493 7.149064294805838e-30 BR00118050 SLC29A1 final orf L20 A549 96 5110 Interphase +0.12932529049306646 9.175428630184146e-30 BR00118050 CSF1R final orf D14 A549 96 4025 Interphase +0.09128011209481789 1.2462099432317341e-29 BR00117006 SSTR2 final orf J01 A549 96 8045 Interphase +0.10681126828307327 4.554325460838874e-29 BR00117006 BRAF final orf I10 A549 96 5765 Interphase +0.10421745409803167 5.668635607111904e-29 BR00117006 SIRT2 final orf A07 A549 96 6040 Interphase +0.08594278541023355 7.817528063706149e-29 BR00117006 PLD1 final orf L05 A549 96 8840 Interphase +0.11333444110621516 1.3290559445448524e-28 BR00117006 GABRB2 final orf C06 A549 96 5035 Interphase +0.11457539648980956 1.3600367754625954e-28 BR00118050 KCNK1 final orf M15 A549 96 4925 Interphase +0.08351315095399225 2.5097143807520955e-28 BR00117006 IMPDH1 final orf L13 A549 96 9190 Interphase +0.11051787103351654 1.5429335677253445e-27 BR00117006 CYP2A6 final orf A20 A549 96 5095 Interphase +0.11286946738513452 2.0231055629265096e-27 BR00118050 DNMT3A final orf H07 A549 96 4855 Interphase +0.09546546298414575 2.4368365994298805e-27 BR00117006 CA14 final orf N07 A549 96 6785 Interphase +0.09452159341860263 7.684895156903463e-27 BR00117006 FLT3 final orf E14 A549 96 6785 Interphase +0.6210675484175721 1.1847568423692868e-26 BR00118049 P3H1 final orf P24 A549 96 145 Interphase +0.08595069568079652 1.2028006012123107e-26 BR00118050 GPR119 final orf N02 A549 96 8160 Interphase +0.08367341768612731 5.045618802288648e-26 BR00118050 ANXA1 final orf N24 A549 96 8395 Interphase +0.08685280058420576 1.4880387574710929e-25 BR00117006 BTK final orf N01 A549 96 7655 Interphase +0.10851282051282052 2.1111361794847185e-25 BR00117006 AKT1 final orf J16 A549 96 4875 Interphase +0.09500407109329129 2.7608223972204155e-25 BR00118050 GAA final orf N04 A549 96 6330 Interphase +0.09568999237063974 2.966207379131151e-25 BR00118050 PNLIP final orf L22 A549 96 6225 Interphase +0.09319625738579149 4.413225839889037e-25 BR00117006 S1PR2 final orf B06 A549 96 6510 Interphase +0.09679346729910077 5.364383474444455e-25 BR00118050 KCNN4 final orf A06 A549 96 6015 Interphase +0.09402454874309395 1.446543920194736e-24 BR00117006 AVPR1A final orf D07 A549 96 6260 Interphase +0.09702633814783347 1.6009922585833234e-24 BR00117006 BRD4 final orf F14 A549 96 5885 Interphase +0.0986711307120943 2.6425828610541904e-24 BR00118050 CTSG final orf J12 A549 96 5630 Interphase +0.09062304045997996 7.408537716339407e-24 BR00117006 ALK final orf J13 A549 96 6555 Interphase +0.10191494760462452 1.4932863689847632e-23 BR00117006 CDK9 final orf N22 A549 96 5115 Interphase +0.09613611345215749 2.373155181287237e-23 BR00117006 SLC29A1 final orf L20 A549 96 5695 Interphase +0.09090959826273094 2.884450522362997e-23 BR00117006 MAPK8 final orf I14 A549 96 6350 Interphase +0.12131312781475381 3.680794717690729e-23 BR00118050 OPRL1 final orf A23 A549 96 3545 Interphase +0.1026369168356998 5.114351205275752e-23 BR00118050 IL1B final orf G08 A549 96 4930 Interphase +0.09610973705439708 8.533235063590717e-23 BR00117006 IL1B final orf G08 A549 96 5555 Interphase +0.08699815507834845 1.4101016737617201e-22 BR00118050 GJB4 final orf P08 A549 96 6715 Interphase +0.09325863077883255 1.4369756346899843e-22 BR00118050 AGER final orf H18 A549 96 5845 Interphase +0.0897575255619582 1.4761622497832534e-22 BR00117006 PIK3CG final orf G18 A549 96 6305 Interphase +0.08893519592660251 2.359963647552816e-22 BR00117006 ASIC1 final orf F12 A549 96 6370 Interphase +0.09619373387760513 4.090058771793377e-22 BR00118050 PTGIS final orf F16 A549 96 5380 Interphase +0.08303620524324276 4.306787660831632e-22 BR00117006 TUBB3 final orf K05 A549 96 7220 Interphase +0.09640046819944216 6.397147152185959e-22 BR00118050 PORCN final orf D22 A549 96 5305 Interphase +0.08377437671998497 1.6705398243989337e-21 BR00117006 EZH2 final orf D04 A549 96 6890 Interphase +0.08983774885999728 6.234372674337505e-21 BR00118050 IGF1R final orf N16 A549 96 5830 Interphase +0.09217482556963953 7.051621713774658e-21 BR00118050 UGT1A9 final orf O09 A549 96 5520 Interphase +0.09344641114403776 8.34644573917676e-21 BR00117006 P3H1 final orf P24 A549 96 5355 Interphase +0.08487339197574231 9.432151865786321e-21 BR00118050 SCNN1G final orf O03 A549 96 6485 Interphase +0.08391502276176024 1.3347695833066176e-20 BR00117006 PTGIR final orf E16 A549 96 6590 Interphase 0.11432032490759339 9.881346991926077e-53 BR00117006 PDPK1 final orf H15 A549 96 9190 Large 0.14406759595081703 5.483297670785891e-49 BR00117006 AKR1C1 final orf A24 A549 96 5360 Large 0.15788219516234492 8.253377146769133e-49 BR00117006 DYRK1B final orf G13 A549 96 4445 Large @@ -1439,6 +14309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.11365824665854579 2.3260224642537994e-46 BR00118050 GPR119 final orf N02 A549 96 8160 Large 0.15571197326282538 9.899898742364853e-46 BR00117006 DYRK1B final orf M12 A549 96 4280 Large 0.09758872748041458 4.99885538958945e-43 BR00118050 HDAC3 final orf N21 A549 96 10275 Large +0.10771858046069828 8.188985069605555e-43 BR00118050 PDE7A final orf J11 A549 96 8380 Large +0.10278290338971101 1.2521753906449846e-41 BR00117006 PDE7A final orf J11 A549 96 8955 Large +0.1408333680492874 1.2162307158772804e-40 BR00117006 UGT1A9 final orf E24 A549 96 4650 Large +0.1084197410620606 3.0951886192862607e-40 BR00118050 GAA final orf N15 A549 96 7775 Large +0.12737177699444757 5.575849140463694e-40 BR00118050 AKR1C1 final orf A24 A549 96 5590 Large +0.11727956352578818 1.0970153656518143e-39 BR00117006 PNLIP final orf L22 A549 96 6545 Large +0.09944812362030905 2.1125468840661038e-39 BR00117006 ASIC1 final orf L21 A549 96 9060 Large +0.13082179258649848 1.110201949431107e-36 BR00117006 CACNG1 final orf A16 A549 96 4860 Large +0.0976 4.330478432975437e-34 BR00118050 HTR3A final orf J23 A549 96 8125 Large +0.09177648322361606 9.577416949338156e-32 BR00117006 CDK9 final orf H11 A549 96 8545 Large +0.10047928405386217 1.0454230161163486e-31 BR00118050 CA5A final orf B02 A549 96 7110 Large +0.10045254140996289 1.4667669298103681e-30 BR00118050 CACNA2D3 final orf L02 A549 96 6860 Large +0.10080704328686721 1.4971959373240638e-30 BR00117006 FGF1 final orf F03 A549 96 6815 Large +0.10606874354664367 6.985923627377358e-30 BR00118050 KCNN4 final orf A06 A549 96 6015 Large +0.11402239084744867 1.3406429077350447e-29 BR00117006 KCNH7 final orf A22 A549 96 5150 Large +0.09214659685863874 1.2293336706799825e-28 BR00118050 PTK2B final orf N19 A549 96 7640 Large +0.1015490920495806 1.5534035044753571e-27 BR00117006 SIRT2 final orf A07 A549 96 6040 Large +0.11447466871977272 2.4671037330864714e-27 BR00117006 HSP90AB1 final orf P01 A549 96 4705 Large +0.08336196798073053 1.702597112817424e-26 BR00117006 LPAR1 final orf B05 A549 96 8610 Large +0.09476172883112946 1.791265169393148e-26 BR00118050 PDE3A final orf O19 A549 96 6660 Large +0.08702474795993752 3.804026089275409e-26 BR00117006 FPR1 final orf D21 A549 96 7805 Large +0.09458279140098765 7.58685741100094e-26 BR00118050 FPR1 final orf D21 A549 96 6525 Large +0.14330985915492958 7.708411175774653e-26 BR00118050 S1PR2 final orf B06 A549 96 2840 Large +0.08050449761846366 4.774763555142555e-25 BR00117006 PTK2B final orf N19 A549 96 8725 Large +0.09280195408541514 5.462254351069959e-25 BR00118050 HCK final orf O01 A549 96 6555 Large +0.07649215649215649 6.249782636987687e-25 BR00117006 HDAC3 final orf N21 A549 96 9620 Large +0.07816581936514436 6.345781372767372e-25 BR00118050 BTK final orf N01 A549 96 9210 Large +0.08128360520077828 7.773502098961121e-25 BR00117006 AURKB final orf L19 A549 96 8490 Large +0.09463427480413457 1.0386559967939282e-24 BR00118050 PNLIP final orf L22 A549 96 6225 Large +0.08213861262602346 1.9066253617130347e-24 BR00118050 AKR1B1 final orf L17 A549 96 8185 Large +0.07525222516874443 5.372593302959684e-24 BR00117006 GPR119 final orf N23 A549 96 9560 Large +0.10224351112487323 1.3121346301721522e-23 BR00117006 CYP2A6 final orf A20 A549 96 5095 Large +0.09817847435304783 1.7094665556877784e-23 BR00118050 CCND1 final orf P16 A549 96 5485 Large +0.08139356750143292 2.789926203013276e-23 BR00117006 PPAT final orf H14 A549 96 7930 Large +0.07821700701631257 3.2359980050807557e-23 BR00117006 GAA final orf N15 A549 96 8550 Large +0.1096958773485491 4.279537557250919e-23 BR00118050 FLT3 final orf K13 A549 96 4320 Large +0.2751875101256609 1.1762399508211364e-22 BR00118049 DYRK1B final orf M12 A549 96 663 Large +0.11449545984086722 3.1161198190668223e-22 BR00117006 P2RY12 final orf B24 A549 96 3810 Large +0.0984323157869582 4.495831789990105e-22 BR00118050 CACNG1 final orf A16 A549 96 5135 Large +0.08811974687255668 4.521774109035611e-22 BR00118050 ADA final orf P03 A549 96 6395 Large +0.09095093959449316 2.5375796392902114e-21 BR00118050 PTPN2 final orf O15 A549 96 5790 Large +0.10694022598104813 2.6968331752638507e-21 BR00117006 HSP90AB1 final orf B16 A549 96 4185 Large +0.10377356569011706 3.0502559458169535e-21 BR00118050 GRIN2A final orf A05 A549 96 4430 Large +0.08419723330845842 1.215101266445209e-20 BR00117006 LYN final orf C20 A549 96 6555 Large +0.09129201825081644 1.3599280849487074e-20 BR00117006 IL1B final orf G08 A549 96 5555 Large +0.09584399663405446 1.4435721883870603e-20 BR00117006 GABRB2 final orf C06 A549 96 5035 Large +0.07035509422490674 3.2033776698473255e-20 BR00117006 IMPDH1 final orf L13 A549 96 9190 Large +0.0773421926910299 5.41789952911558e-20 BR00118050 KCNQ2 final orf K01 A549 96 7525 Large +0.09315068493150686 1.0434666511610861e-19 BR00118050 SLC29A1 final orf L20 A549 96 5110 Large +0.07694434453486823 1.236199419307268e-19 BR00118050 CACNB4 final orf M01 A549 96 7455 Large +0.08098159509202454 5.157301175657421e-19 BR00117006 KCNK1 final orf M15 A549 96 6520 Large +0.08690121214985912 1.2981677052845204e-18 BR00118050 UGT1A9 final orf O09 A549 96 5520 Large +0.09386258435993936 1.6008071972478275e-18 BR00118050 PDE4D final orf B22 A549 96 4705 Large +0.0787032365970728 1.6153457882313653e-18 BR00117006 AKT1 final orf F15 A549 96 6710 Large +0.06583989265310075 3.1550299454479763e-18 BR00118050 AURKB final orf L19 A549 96 9430 Large +0.0765767986089346 3.5315874730506145e-18 BR00118050 PTK2B final orf J18 A549 96 6955 Large +0.1071203792057841 3.7522323484193435e-18 BR00118050 OPRL1 final orf A23 A549 96 3545 Large +0.08269218145493519 8.62973603074349e-18 BR00118050 P2RY12 final orf B01 A549 96 5830 Large +0.08252041917485291 8.847664802055003e-18 BR00118050 AGER final orf H18 A549 96 5845 Large +0.07943431746785687 2.5536540356965287e-17 BR00118050 KCNH7 final orf A22 A549 96 6145 Large +0.07830024144727225 2.895078611307379e-17 BR00117006 ALK final orf H12 A549 96 6300 Large +0.07467589329932284 3.4065146876840884e-17 BR00117006 ADA final orf P03 A549 96 6910 Large +0.07779422185479347 1.117161980514896e-16 BR00117006 GUCY1B1 final orf J08 A549 96 6160 Large +0.07682750666683635 1.1189055662681566e-16 BR00118050 GAA final orf N04 A549 96 6330 Large +0.06263962974013404 1.9116818082369993e-16 BR00118050 ITGB2 final orf P21 A549 96 9380 Large +0.0839814379260653 2.3391042755856933e-16 BR00118050 PAK4 final orf G10 A549 96 5175 Large +0.07958477508650519 2.43499658578162e-16 BR00117006 PTGIS final orf F16 A549 96 5780 Large +0.08266400254283271 3.2519919083364354e-16 BR00118050 SLCO2B1 final orf O13 A549 96 5295 Large +0.07850467289719626 3.424974837748089e-16 BR00117006 GHSR final orf C24 A549 96 5885 Large +0.08126114500390866 3.608860177447504e-16 BR00118050 HRH4 final orf O05 A549 96 5480 Large +0.0722114556416882 4.6899554629358855e-16 BR00118050 CDK4 final orf P20 A549 96 6880 Large +0.08726831157928078 4.75266288508132e-16 BR00118050 DNMT3A final orf F04 A549 96 4715 Large +0.08799765632542454 6.596015011024735e-16 BR00118050 KDR final orf O02 A549 96 4585 Large +0.07504885435957112 7.241375739421369e-16 BR00118050 F10 final orf C09 A549 96 6285 Large +0.08471794871794872 1.2275723745163998e-15 BR00117006 AKT1 final orf J16 A549 96 4875 Large +0.08670270270270271 1.528398670660546e-15 BR00118050 CHRM3 final orf A10 A549 96 4625 Large +0.060198954904445955 1.5505604317948518e-15 BR00118050 S1PR1 final orf L01 A549 96 9575 Large +0.08553326293558607 1.7371756610047589e-15 BR00118050 PLA2G1B final orf E06 A549 96 4735 Large +0.06333719551167027 2.3004142014527803e-15 BR00117006 PRKCE final orf J19 A549 96 8555 Large +0.07384281384636814 2.410416268527641e-15 BR00118050 AVPR1A final orf D07 A549 96 6290 Large +0.07663330712946725 3.990073048717534e-15 BR00118050 HIF1A final orf C23 A549 96 5750 Large +0.06994892839829085 5.612357971741288e-15 BR00118050 PRKCE final orf J19 A549 96 6825 Large +0.07611164617424394 8.170594720352064e-15 BR00118050 S1PR4 final orf M17 A549 96 5705 Large +0.07229445726190466 9.084331041926874e-15 BR00117006 PDE3A final orf O19 A549 96 6305 Large +0.07113560052598908 1.0657631831835677e-14 BR00118050 SCNN1G final orf O03 A549 96 6485 Large +0.08540531902142791 1.8293916998356625e-14 BR00117006 CLK1 final orf D08 A549 96 4420 Large +0.06574546753710274 1.897003804497184e-14 BR00117006 DHH final orf G05 A549 96 7460 Large +0.07164885010050044 1.9292060915940784e-14 BR00118050 ALDH2 final orf P14 A549 96 6260 Large +0.07984495893964261 2.1398838987646094e-14 BR00117006 OPRM1 final orf A09 A549 96 5025 Large +0.06714195783712579 3.082231925894541e-14 BR00118050 HPGDS final orf O21 A549 96 7030 Large 0.09654206570729777 3.3429571749821326e-22 BR00117006 AKR1C1 final orf A24 A549 96 5360 Metaphase 0.06766190428568308 1.3109882023010989e-21 BR00118050 TBXAS1 final orf P23 A549 96 10635 Metaphase 0.08610264486587187 1.4316477859347417e-21 BR00118050 HCK final orf O01 A549 96 6555 Metaphase @@ -1449,6 +14409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.07030658542300637 1.7528175930994502e-17 BR00117006 PPAT final orf H14 A549 96 7930 Metaphase 0.06912324808609822 8.63771487815649e-17 BR00117006 P2RY12 final orf B01 A549 96 7860 Metaphase 0.0748807990527666 2.2814416137788705e-15 BR00118050 MAPK14 final orf G22 A549 96 6110 Metaphase +0.07021121631463947 3.914660511273963e-15 BR00117006 CHRM3 final orf A10 A549 96 6865 Metaphase +0.05644573443006873 1.4316863549467712e-14 BR00117006 BRD4 final orf N17 A549 96 10205 Metaphase +0.05985615774569524 2.4754691121108324e-14 BR00117006 HTR3A final orf J23 A549 96 8910 Metaphase +0.06545987495778716 2.480619801083811e-13 BR00117006 ADA final orf P03 A549 96 6910 Metaphase +0.0942535558251524 3.9371228181908976e-13 BR00118050 DYRK1B final orf G13 A549 96 3280 Metaphase +0.10035211267605634 7.266418510750618e-13 BR00118050 S1PR2 final orf B06 A549 96 2840 Metaphase +0.08405683908968549 8.377058375440687e-13 BR00118050 CSF1R final orf D14 A549 96 4025 Metaphase +0.07246473056159074 1.4356093485301538e-12 BR00118050 PORCN final orf D22 A549 96 5305 Metaphase +0.07890314738781934 1.8434837034773912e-12 BR00118050 GRIN2A final orf A05 A549 96 4430 Metaphase +0.06293815760585027 2.681781452897183e-12 BR00118050 CDK4 final orf P20 A549 96 6880 Metaphase +0.0738798921913506 3.2176048068269493e-12 BR00118050 SLC7A11 final orf G24 A549 96 4960 Metaphase +0.060814338829237015 1.3825696348626881e-11 BR00117006 USP1 final orf E12 A549 96 6935 Metaphase +0.06256725595695618 1.719494988694466e-11 BR00117006 NTRK1 final orf P02 A549 96 6505 Metaphase +0.0547860455970026 2.913455851391658e-11 BR00117006 JAK1 final orf H17 A549 96 8280 Metaphase +0.05366703086031992 3.449946229222461e-11 BR00117006 PTGIS final orf H13 A549 96 8580 Metaphase +0.05164399946587419 4.319158855927882e-11 BR00117006 PDPK1 final orf H15 A549 96 9190 Metaphase +0.0651133543344401 5.0295827997566434e-11 BR00118050 DYRK1B final orf M12 A549 96 5735 Metaphase +0.050894187214884305 8.824201032645101e-11 BR00117006 IMPDH1 final orf L13 A549 96 9190 Metaphase +0.05625422582826234 1.3586160850342296e-10 BR00117006 ATP5F1D final orf G14 A549 96 7395 Metaphase +0.05716076234308676 2.007660831832777e-10 BR00118050 HPGDS final orf O21 A549 96 7030 Metaphase +0.05350052321957113 2.744526980666538e-10 BR00117006 HCK final orf O20 A549 96 7900 Metaphase +0.059464246191933974 2.8394475932159073e-10 BR00117006 KRAS final orf D17 A549 96 6390 Metaphase +0.06408639078306892 2.9735924407615164e-10 BR00118050 PPAT final orf F11 A549 96 5485 Metaphase +0.06942023840877601 3.0629287271683636e-10 BR00118050 KCNK1 final orf C22 A549 96 4675 Metaphase +0.07616713575344905 3.084518427351158e-10 BR00118050 HTR2C final orf G21 A549 96 3880 Metaphase +0.05093640487845559 4.556258355767623e-10 BR00117006 CDK9 final orf H11 A549 96 8545 Metaphase +0.06540474456548398 5.080852515421407e-10 BR00117006 KCNH7 final orf A22 A549 96 5150 Metaphase +0.06504603185269807 5.472902626967113e-10 BR00118050 S1PR1 final orf P22 A549 96 5175 Metaphase +0.05463983658136344 5.951026172747544e-10 BR00117006 AGER final orf H09 A549 96 7315 Metaphase +0.05652429919490155 6.108650582909452e-10 BR00118050 ASIC1 final orf L21 A549 96 6840 Metaphase +0.055986455791464745 6.838172922697022e-10 BR00118050 KCNQ2 final orf K02 A549 96 6935 Metaphase +0.0548422150490019 7.887819930513826e-10 BR00118050 TBXAS1 final orf J24 A549 96 7175 Metaphase +0.057829457364341086 8.484546581261829e-10 BR00118050 CLK1 final orf J17 A549 96 6450 Metaphase +0.051741293532338306 8.902623267731809e-10 BR00117006 MAPK14 final orf G15 A549 96 8040 Metaphase +0.05299234583274506 9.719940099669257e-10 BR00118050 PRKCE final orf L14 A549 96 7615 Metaphase +0.0544318359624697 1.087388328638876e-09 BR00117006 BAX final orf K17 A549 96 7190 Metaphase +0.05483590550040295 1.1379012308143765e-09 BR00117006 CDK2 final orf J04 A549 96 7050 Metaphase +0.05558664539327983 1.1694474045779731e-09 BR00118050 CACNA2D3 final orf L02 A549 96 6860 Metaphase +0.051066613209994546 1.4693134423295858e-09 BR00117006 CACNA2D3 final orf P19 A549 96 8055 Metaphase +0.06713843635089849 1.6149414149333536e-09 BR00118050 TNF final orf C13 A549 96 4620 Metaphase +0.06724324324324324 1.6327106772815883e-09 BR00118050 CHRM3 final orf A10 A549 96 4625 Metaphase +0.05569107889260744 1.7729799112562816e-09 BR00118050 P3H1 final orf F23 A549 96 6705 Metaphase +0.047251246380008986 2.2417299993227114e-09 BR00118050 BTK final orf N01 A549 96 9210 Metaphase +0.05945017182130584 2.3077889457644374e-09 BR00118050 MAPK8 final orf I14 A549 96 5820 Metaphase +0.05641759750548906 2.7617677238365793e-09 BR00117006 AKR1B1 final orf L10 A549 96 6390 Metaphase +0.06184210526315789 2.8843153113009514e-09 BR00118050 CYP1A2 final orf N12 A549 96 5320 Metaphase +0.0696346404150397 2.9375969929886163e-09 BR00117006 CA5A final orf B23 A549 96 4180 Metaphase +0.20637116506681724 4.0246383084143394e-09 BR00118049 PTK2B final orf J18 A549 96 460 Metaphase +0.05738006489824968 4.244929929479311e-09 BR00117006 ANXA1 final orf D23 A549 96 6040 Metaphase +0.25624359332774205 5.4734677356814406e-09 BR00118049 PRKCE final orf J19 A549 96 294 Metaphase +0.05777400169923534 5.83562768515826e-09 BR00117006 GHSR final orf C24 A549 96 5885 Metaphase +0.049935258168111896 7.152380690212565e-09 BR00117006 EDNRB final orf K11 A549 96 7785 Metaphase +0.04811107551671682 9.286911647971829e-09 BR00117006 SCNN1G final orf O03 A549 96 8280 Metaphase +0.05036544850498339 1.0186868567753773e-08 BR00118050 KCNQ2 final orf K01 A549 96 7525 Metaphase +0.0642458366247662 1.077341979558896e-08 BR00118050 KDR final orf O02 A549 96 4585 Metaphase +0.048713088406075945 1.0870841578130747e-08 BR00118050 CDK9 final orf N22 A549 96 7990 Metaphase +0.06082272601580467 1.0876859765204228e-08 BR00118050 CACNG1 final orf A16 A549 96 5135 Metaphase +0.05118655551044088 1.5611643211841593e-08 BR00118050 CA5A final orf B02 A549 96 7110 Metaphase +0.04321533497660255 2.1702769011908914e-08 BR00117006 EZH2 final orf D03 A549 96 9780 Metaphase +0.059309021113243765 2.1778604194818576e-08 BR00118050 OPRM1 final orf A09 A549 96 5210 Metaphase +0.0640526642859422 2.2289089524541174e-08 BR00117006 DYRK1B final orf G13 A549 96 4445 Metaphase +0.05237568778551308 2.441884003463649e-08 BR00118050 KCNMA1 final orf G01 A549 96 6620 Metaphase +0.04997434695523381 2.6130193967760618e-08 BR00118050 HSD11B1 final orf C02 A549 96 7235 Metaphase +0.044723354739039566 3.0758337623976556e-08 BR00117006 CDK4 final orf B21 A549 96 8975 Metaphase +0.0480313846609318 3.129763997018754e-08 BR00117006 FLT3 final orf K13 A549 96 7765 Metaphase +0.0611344537815126 3.7227990620764445e-08 BR00118050 NAMPT final orf D13 A549 96 4760 Metaphase +0.056411422842572445 4.007110388299573e-08 BR00117006 IL1B final orf G08 A549 96 5555 Metaphase +0.041005206589976195 6.105242618425136e-08 BR00118050 HDAC3 final orf N21 A549 96 10275 Metaphase +0.07856283307546845 6.98952573268542e-08 BR00118050 LPAR1 final orf B20 A549 96 2770 Metaphase +0.05987261146496815 9.22064491206791e-08 BR00118050 DDR2 final orf A19 A549 96 4710 Metaphase +0.052156310319427496 1.1620337040645988e-07 BR00118050 P3H1 final orf P24 A549 96 6100 Metaphase +0.23841374269005847 1.2372261879828683e-07 BR00118049 PDE7A final orf J11 A549 96 288 Metaphase +0.055924170616113746 1.3587544117427963e-07 BR00118050 PTGIS final orf H13 A549 96 5275 Metaphase +0.04686579087416187 1.4579190078980438e-07 BR00118050 CACNB4 final orf M01 A549 96 7455 Metaphase +0.04871226896884123 1.936277464718238e-07 BR00117006 CA14 final orf N07 A549 96 6785 Metaphase +0.049912801434135554 2.0633505064096465e-07 BR00118050 ADRA2B final orf J03 A549 96 6440 Metaphase +0.05102543068088597 2.5516599232543026e-07 BR00118050 PTPN2 final orf I02 A549 96 6095 Metaphase +0.05479935794542536 2.593065589751964e-07 BR00118050 PNLIP final orf J09 A549 96 5250 Metaphase +0.050626305146202116 2.684961248344924e-07 BR00118050 CACNA2D3 final orf P19 A549 96 6155 Metaphase +0.05023846841142282 2.840739640912795e-07 BR00118050 BRAF final orf I10 A549 96 6235 Metaphase +0.04968535209826879 3.549604109597125e-07 BR00118050 F10 final orf C09 A549 96 6285 Metaphase +0.04499066535910137 4.156615616743806e-07 BR00118050 SSTR2 final orf J01 A549 96 7570 Metaphase +0.08477751756440281 4.2703001511902373e-07 BR00118050 ANXA1 final orf D23 A549 96 2135 Metaphase +0.049156934274909386 4.974919211417486e-07 BR00118050 S1PR2 final orf B19 A549 96 6260 Metaphase +0.04574081016584813 5.350195669493212e-07 BR00117006 TUBB3 final orf K05 A549 96 7220 Metaphase +0.04642712804867778 5.891374276910594e-07 BR00118050 PTK2B final orf J18 A549 96 6955 Metaphase +0.04222433854838255 6.112568296352824e-07 BR00118050 PDE7A final orf J11 A549 96 8380 Metaphase +0.052611899001538086 6.544395197177971e-07 BR00118050 CA14 final orf J14 A549 96 5385 Metaphase +0.14926878466969237 6.832279814570704e-07 BR00118049 DYRK1B final orf M12 A549 96 663 Metaphase +0.19836817950025498 7.252940234413287e-07 BR00118049 AKT1 final orf F15 A549 96 370 Metaphase 0.10971344762051474 8.358535571858439e-44 BR00117006 JAK1 final orf H17 A549 96 8280 MetaphaseAlignment 0.09533481759921494 2.711970343878966e-38 BR00118050 S1PR1 final orf L01 A549 96 9575 MetaphaseAlignment 0.10171674498212802 3.7288913920868416e-38 BR00118050 PDE7A final orf J11 A549 96 8380 MetaphaseAlignment @@ -1459,6 +14509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.08482276297732899 1.3468358312294377e-32 BR00118050 HDAC3 final orf N21 A549 96 10275 MetaphaseAlignment 0.09094768002261161 3.16085853703084e-32 BR00117006 ALDH2 final orf P13 A549 96 8835 MetaphaseAlignment 0.08951434878587196 5.400511468203589e-32 BR00117006 ASIC1 final orf L21 A549 96 9060 MetaphaseAlignment +0.08742010810942123 8.976953952989447e-32 BR00118050 AURKB final orf L19 A549 96 9430 MetaphaseAlignment +0.08805357547036691 1.8213212979107822e-31 BR00117006 PDPK1 final orf H15 A549 96 9190 MetaphaseAlignment +0.08704799988356608 2.2589235124995354e-31 BR00118050 ITGB2 final orf P21 A549 96 9380 MetaphaseAlignment +0.08513127215816538 1.3592470663758359e-30 BR00117006 GPR119 final orf N23 A549 96 9560 MetaphaseAlignment +0.12934535643283157 7.742237489949553e-30 BR00118050 CSF1R final orf D14 A549 96 4025 MetaphaseAlignment +0.0790275914628889 2.490467806270474e-29 BR00118050 TBXAS1 final orf P23 A549 96 10635 MetaphaseAlignment +0.0887881939142356 3.148436408318547e-28 BR00118050 ALDH2 final orf P13 A549 96 8095 MetaphaseAlignment +0.10093457943925234 1.662163861798213e-26 BR00117006 GHSR final orf C24 A549 96 5885 MetaphaseAlignment +0.07844712044712045 3.3023949551399135e-26 BR00117006 HDAC3 final orf N21 A549 96 9620 MetaphaseAlignment +0.10491982974266406 3.7064243193659484e-26 BR00117006 AKR1C1 final orf A24 A549 96 5360 MetaphaseAlignment +0.08472262415635497 5.265240818456815e-26 BR00118050 AKR1B1 final orf L17 A549 96 8185 MetaphaseAlignment +0.10700364775528458 7.224745457992204e-26 BR00117006 CYP2A6 final orf A20 A549 96 5095 MetaphaseAlignment +0.0832089552238806 1.2554029388161656e-24 BR00118050 BRD4 final orf N17 A549 96 8040 MetaphaseAlignment +0.10688810166434591 1.2711392394249864e-24 BR00118050 DNMT3A final orf H07 A549 96 4855 MetaphaseAlignment +0.07852992275832164 1.7547361835961938e-24 BR00117006 PDE7A final orf J11 A549 96 8955 MetaphaseAlignment +0.07356566393635433 1.8566433785428972e-24 BR00117006 BRD4 final orf N17 A549 96 10205 MetaphaseAlignment +0.08227104669764837 4.113985467475282e-24 BR00117006 SSTR2 final orf J01 A549 96 8045 MetaphaseAlignment +0.10565913233832618 4.473058421269899e-24 BR00118050 PDE4D final orf B17 A549 96 4855 MetaphaseAlignment +0.08220997556017688 1.594868591470343e-23 BR00118050 GJB4 final orf H23 A549 96 7840 MetaphaseAlignment +0.08050985928300033 1.981925622320125e-22 BR00117006 FPR1 final orf D21 A549 96 7805 MetaphaseAlignment +0.09580116255149845 2.264945352970304e-22 BR00118050 PPAT final orf F11 A549 96 5485 MetaphaseAlignment +0.0738965050041168 9.473767337672236e-22 BR00117006 CDK4 final orf B21 A549 96 8975 MetaphaseAlignment +0.08010471204188482 9.74339543883379e-22 BR00118050 PTK2B final orf N19 A549 96 7640 MetaphaseAlignment +0.07921394253228042 1.1332347543368445e-21 BR00118050 GAA final orf N15 A549 96 7775 MetaphaseAlignment +0.07430947646709946 1.1774389480208416e-21 BR00117006 CHRM2 final orf B03 A549 96 8835 MetaphaseAlignment +0.09216637439810758 1.7275596354955476e-21 BR00117006 SLC29A1 final orf L20 A549 96 5695 MetaphaseAlignment +0.08889556500303336 1.3195115998576565e-20 BR00117006 ADRA2B final orf N18 A549 96 5860 MetaphaseAlignment +0.07257889177709201 1.9019823834120796e-20 BR00117006 PTK2B final orf N19 A549 96 8725 MetaphaseAlignment +0.10278597039093222 2.573657599507961e-20 BR00118050 FLT3 final orf K13 A549 96 4320 MetaphaseAlignment +0.10121740342328578 4.3895028189218563e-20 BR00118050 UGT1A9 final orf E24 A549 96 4400 MetaphaseAlignment +0.09156398104265402 1.172414100839277e-19 BR00118050 CDK9 final orf H11 A549 96 5275 MetaphaseAlignment +0.07262579857331979 3.4646821380778047e-19 BR00118050 GPR119 final orf N02 A549 96 8160 MetaphaseAlignment +0.08598615916955017 5.24898960669162e-19 BR00117006 PTGIS final orf F16 A549 96 5780 MetaphaseAlignment +0.06802860707731004 5.427327627462907e-19 BR00118050 BTK final orf N01 A549 96 9210 MetaphaseAlignment +0.09190318012387058 5.810715342613595e-19 BR00117006 GABRB2 final orf C06 A549 96 5035 MetaphaseAlignment +0.08089602158352573 6.16900282288905e-19 BR00118050 SCNN1G final orf O03 A549 96 6485 MetaphaseAlignment +0.07274565490183828 1.8020623023128477e-18 BR00117006 CLK1 final orf J17 A549 96 7840 MetaphaseAlignment +0.07148450034251357 8.171694441640313e-18 BR00117006 GJB4 final orf H23 A549 96 7825 MetaphaseAlignment +0.06938565534239766 9.025122429019877e-18 BR00117006 SCNN1G final orf O03 A549 96 8280 MetaphaseAlignment +0.08402860204800756 1.2621680345746937e-17 BR00118050 AKR1C1 final orf A24 A549 96 5590 MetaphaseAlignment +0.09352236636879468 2.5804059828612484e-17 BR00118050 GRIN2A final orf A05 A549 96 4430 MetaphaseAlignment +0.07788343497019931 2.9836136717905346e-17 BR00117006 ASIC1 final orf F12 A549 96 6370 MetaphaseAlignment +0.08077571669477235 3.024098041737069e-17 BR00117006 NAMPT final orf L06 A549 96 5930 MetaphaseAlignment +0.07806752940144789 8.051676862275897e-17 BR00118050 GLRA3 final orf K04 A549 96 6170 MetaphaseAlignment +0.06840394794405957 1.690827251077084e-16 BR00117006 HCK final orf O20 A549 96 7900 MetaphaseAlignment +0.07458603295339383 1.8069479293422835e-16 BR00117006 CCND1 final orf P16 A549 96 6625 MetaphaseAlignment +0.07462314221087413 2.8259370748842055e-16 BR00117006 PNLIP final orf L22 A549 96 6545 MetaphaseAlignment +0.08392966462526855 4.196357563930836e-16 BR00117006 CDK9 final orf N22 A549 96 5115 MetaphaseAlignment +0.08924033762772102 4.8869861882031885e-16 BR00117006 TNNC1 final orf M18 A549 96 4500 MetaphaseAlignment +0.07113339881162503 5.494542039950262e-16 BR00117006 FOXM1 final orf J02 A549 96 7070 MetaphaseAlignment +0.08300032106563926 5.525074701283556e-16 BR00118050 PAK4 final orf G10 A549 96 5175 MetaphaseAlignment +0.09333754312751101 8.198665181826901e-16 BR00118050 HSD11B1 final orf G23 A549 96 4050 MetaphaseAlignment +0.07657581039447985 1.57391328027591e-15 BR00118050 ADRA2B final orf N18 A549 96 5910 MetaphaseAlignment +0.06138729708664676 1.62305654015208e-15 BR00117006 IMPDH1 final orf L13 A549 96 9190 MetaphaseAlignment +0.07120657581888885 3.5297761995027283e-15 BR00117006 RPL23A final orf I07 A549 96 6690 MetaphaseAlignment +0.08870424445367237 5.16020546580611e-15 BR00118050 IMPDH1 final orf N20 A549 96 4255 MetaphaseAlignment +0.07329299065105868 5.870453140163625e-15 BR00118050 PLK1 final orf N08 A549 96 6215 MetaphaseAlignment +0.07679906035383195 7.06053482006417e-15 BR00117006 AGER final orf H18 A549 96 5630 MetaphaseAlignment +0.06913567227190927 1.0492802796334851e-14 BR00118050 CACNA2D3 final orf L02 A549 96 6860 MetaphaseAlignment +0.08978467548718888 1.1954233614007679e-14 BR00117006 MMP2 final orf F06 A549 96 4050 MetaphaseAlignment +0.07408896187185328 1.3200436015158283e-14 BR00118050 FFAR2 final orf B15 A549 96 5920 MetaphaseAlignment +0.07264346494789665 1.7051283817413312e-14 BR00117006 ERBB2 final orf E21 A549 96 6115 MetaphaseAlignment +0.07058496799251666 1.875734282776995e-14 BR00117006 CASP3 final orf J10 A549 96 6455 MetaphaseAlignment +0.0795560208334688 3.927042978859931e-14 BR00118050 SLC7A11 final orf G24 A549 96 4960 MetaphaseAlignment +0.06889724111323485 5.329955729020806e-14 BR00118050 HCK final orf O01 A549 96 6555 MetaphaseAlignment +0.08227228920573823 8.273484468121868e-14 BR00118050 KRAS final orf F08 A549 96 4540 MetaphaseAlignment +0.07040209426885431 1.0923172524361656e-13 BR00118050 FLT3 final orf E14 A549 96 6145 MetaphaseAlignment +0.07383255735784944 1.5346695705606795e-13 BR00118050 UGT1A9 final orf O09 A549 96 5520 MetaphaseAlignment +0.06949144351333596 1.7057459915527298e-13 BR00117006 KCNN1 final orf A01 A549 96 6220 MetaphaseAlignment +0.06900369360484229 2.0099930238167684e-13 BR00118050 HDAC6 final orf E20 A549 96 6270 MetaphaseAlignment +0.06820759356839624 2.8796990143557864e-13 BR00118050 ADH1C final orf M23 A549 96 6330 MetaphaseAlignment +0.06737150794875753 3.0314732762470386e-13 BR00117006 ELANE final orf D19 A549 96 6480 MetaphaseAlignment +0.06899930615016682 3.4061736453645087e-13 BR00117006 GUCY1B1 final orf J08 A549 96 6160 MetaphaseAlignment +0.07051826677994902 3.818515556277353e-13 BR00117006 BRD4 final orf F14 A549 96 5885 MetaphaseAlignment +0.06365326859815185 3.9103396101450117e-13 BR00117006 CACNB4 final orf M01 A549 96 7210 MetaphaseAlignment +0.090207871298697 5.455124422218757e-13 BR00118050 OPRL1 final orf A23 A549 96 3545 MetaphaseAlignment +0.07495107632093934 6.661669486028563e-13 BR00118050 SLC29A1 final orf L20 A549 96 5110 MetaphaseAlignment +0.06879701839379258 6.803542969763803e-13 BR00118050 CLK1 final orf D08 A549 96 6045 MetaphaseAlignment +0.06947343285694071 7.425730169843827e-13 BR00117006 RPL23A final orf G16 A549 96 5920 MetaphaseAlignment +0.05814319443008429 8.726158261302933e-13 BR00118050 ANXA1 final orf N24 A549 96 8395 MetaphaseAlignment +0.06727153666474704 1.0179724220453334e-12 BR00117006 ICAM1 final orf I08 A549 96 6235 MetaphaseAlignment +0.06656131853305594 1.5897641868871657e-12 BR00118050 ALDH2 final orf P14 A549 96 6260 MetaphaseAlignment +0.06907216494845361 1.7115982148764193e-12 BR00118050 MAPK8 final orf I14 A549 96 5820 MetaphaseAlignment +0.06611240908661035 1.7446802050389869e-12 BR00118050 GAA final orf N04 A549 96 6330 MetaphaseAlignment +0.07161436110884128 1.7601527456912512e-12 BR00118050 AKR1B1 final orf L10 A549 96 5385 MetaphaseAlignment +0.06764680240687189 1.7686893704772243e-12 BR00117006 SIRT2 final orf A07 A549 96 6040 MetaphaseAlignment +0.05661633039674737 1.989546487066635e-12 BR00117006 LPAR1 final orf B05 A549 96 8610 MetaphaseAlignment +0.06288836749175174 2.1530164148591256e-12 BR00117006 ADRA2B final orf J03 A549 96 6945 MetaphaseAlignment +0.06520142380925475 2.314150316680377e-12 BR00118050 ATP5F1D final orf G14 A549 96 6435 MetaphaseAlignment +0.07449392712550608 2.4297154125376965e-12 BR00117006 IMPDH1 final orf N20 A549 96 4940 MetaphaseAlignment 0.144173150919095 1.2662961599832006e-93 BR00118050 HDAC3 final orf N21 A549 96 10275 OutOfFocus 0.15111605303755643 6.139686335375949e-92 BR00117006 PDPK1 final orf H15 A549 96 9190 OutOfFocus 0.15957711442786068 1.0209881833608381e-89 BR00118050 BRD4 final orf N17 A549 96 8040 OutOfFocus @@ -1469,6 +14609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.14701986754966886 8.884267186582924e-86 BR00117006 ASIC1 final orf L21 A549 96 9060 OutOfFocus 0.14067715100645592 8.102018729257072e-82 BR00118050 AURKB final orf L19 A549 96 9430 OutOfFocus 0.13640839840292773 4.557442139253839e-78 BR00118050 S1PR1 final orf L01 A549 96 9575 OutOfFocus +0.1472 3.708404931129993e-77 BR00118050 HTR3A final orf J23 A549 96 8125 OutOfFocus +0.13366159208831513 1.8342169857389086e-73 BR00118050 ITGB2 final orf P21 A549 96 9380 OutOfFocus +0.13185020385020385 2.291558426706013e-73 BR00117006 HDAC3 final orf N21 A549 96 9620 OutOfFocus +0.12483183027287648 1.1213177147676018e-72 BR00118050 TBXAS1 final orf P23 A549 96 10635 OutOfFocus +0.14056862500299716 2.0183831530429333e-67 BR00118050 GAA final orf N15 A549 96 7775 OutOfFocus +0.12303083152978493 1.8402791272416636e-59 BR00117006 PDE7A final orf J11 A549 96 8955 OutOfFocus +0.1275966043609476 1.8203466847238098e-58 BR00118050 AKR1B1 final orf L17 A549 96 8185 OutOfFocus +0.12338889649518357 2.673499616892882e-58 BR00117006 PTK2B final orf N19 A549 96 8725 OutOfFocus +0.12367921445895644 5.563409514896892e-57 BR00117006 AURKB final orf L19 A549 96 8490 OutOfFocus +0.12256371295698205 2.510205768142947e-56 BR00117006 CDK9 final orf H11 A549 96 8545 OutOfFocus +0.1193966372434312 5.284689417567063e-49 BR00117006 GJB4 final orf H23 A549 96 7825 OutOfFocus +0.12253943174317627 2.3949496603013483e-48 BR00118050 PDPK1 final orf H15 A549 96 7325 OutOfFocus +0.10858187570247536 1.0380456018943174e-47 BR00118050 BTK final orf N01 A549 96 9210 OutOfFocus +0.14306114320739255 6.935578824805139e-46 BR00117006 CYP2A6 final orf A20 A549 96 5095 OutOfFocus +0.10388995587779884 1.345765894159593e-43 BR00117006 IMPDH1 final orf L13 A549 96 9190 OutOfFocus +0.10549040614370916 1.6061980960991688e-40 BR00117006 JAK1 final orf H17 A549 96 8280 OutOfFocus +0.10593327362803963 2.744184531763909e-40 BR00118050 GPR119 final orf N02 A549 96 8160 OutOfFocus +0.1152453980425309 3.929528083457197e-40 BR00118050 CACNA2D3 final orf L02 A549 96 6860 OutOfFocus +0.13845092784173227 2.6853768944357157e-39 BR00117006 UGT1A9 final orf E24 A549 96 4650 OutOfFocus +0.1484722102169591 3.4860406176884066e-39 BR00118050 CSF1R final orf D14 A549 96 4025 OutOfFocus +0.12251486830926084 7.000565654546311e-39 BR00117006 GHSR final orf C24 A549 96 5885 OutOfFocus +0.1011348764069258 8.41436413159082e-39 BR00117006 LPAR1 final orf B05 A549 96 8610 OutOfFocus +0.10488106733574695 5.780143056819576e-38 BR00118050 GJB4 final orf H23 A549 96 7840 OutOfFocus +0.09707688543869693 3.067006505235567e-37 BR00117006 CDK4 final orf B21 A549 96 8975 OutOfFocus +0.1136008748909655 3.368418613398394e-37 BR00117006 PNLIP final orf L22 A549 96 6545 OutOfFocus +0.10500333555703803 2.229101675879706e-36 BR00117006 PARP3 final orf H21 A549 96 7495 OutOfFocus +0.10843324726674677 2.2956226984211602e-36 BR00117006 PARP3 final orf J20 A549 96 7020 OutOfFocus +0.09570836842203403 6.016176919624172e-36 BR00117006 HTR3A final orf J23 A549 96 8910 OutOfFocus +0.14596811285263003 6.660080267923573e-36 BR00117006 P2RY12 final orf B24 A549 96 3810 OutOfFocus +0.1235968874751121 4.5173986178253085e-35 BR00117006 PLA2G1B final orf E06 A549 96 5205 OutOfFocus +0.12367906066536204 1.8646544677919894e-34 BR00118050 SLC29A1 final orf L20 A549 96 5110 OutOfFocus +0.09895072418381498 1.1104687146872419e-33 BR00117006 FPR1 final orf D21 A549 96 7805 OutOfFocus +0.09765422625230727 5.125085070805387e-33 BR00117006 CLK1 final orf J17 A549 96 7840 OutOfFocus +0.11114510647677514 6.48568567477282e-33 BR00117006 SIRT2 final orf A07 A549 96 6040 OutOfFocus +0.10942632632748932 6.738263729658368e-33 BR00118050 PNLIP final orf L22 A549 96 6225 OutOfFocus +0.09878387764388973 2.0226772912999047e-32 BR00117006 LCK final orf B18 A549 96 7535 OutOfFocus +0.11996982963452968 5.006202611621261e-32 BR00117006 GABRB2 final orf C06 A549 96 5035 OutOfFocus +0.09178003104224085 8.240807535779196e-32 BR00117006 GAA final orf N15 A549 96 8550 OutOfFocus +0.08950530561873217 2.915818879867305e-31 BR00117006 CHRM2 final orf B03 A549 96 8835 OutOfFocus +0.11135297431009084 2.713236877119049e-30 BR00118050 UGT1A9 final orf O09 A549 96 5520 OutOfFocus +0.09165001891337914 3.400983582437071e-30 BR00117006 CSF1R final orf J07 A549 96 8135 OutOfFocus +0.12021621621621621 1.6051926179501844e-29 BR00118050 CHRM3 final orf A10 A549 96 4625 OutOfFocus +0.10111347270247122 1.6892834512778336e-29 BR00118050 FPR1 final orf D21 A549 96 6525 OutOfFocus +0.13678892446497534 2.4480630093280746e-29 BR00118050 OPRL1 final orf A23 A549 96 3545 OutOfFocus +0.09751052113649211 1.0697924163044425e-28 BR00118050 PRKCE final orf J19 A549 96 6825 OutOfFocus +0.08662518609083342 1.3651226775810048e-28 BR00117006 S1PR1 final orf L01 A549 96 8615 OutOfFocus +0.09642326845600896 1.4084835522258888e-28 BR00118050 PTK2B final orf J18 A549 96 6955 OutOfFocus +0.1142220766403773 4.214726610330522e-28 BR00117006 CACNG1 final orf A16 A549 96 4860 OutOfFocus +0.09694258016405667 7.0145803781071075e-28 BR00118050 P3H1 final orf F23 A549 96 6705 OutOfFocus +0.11173349944412016 3.282598189071378e-27 BR00118050 KCNK1 final orf M15 A549 96 4925 OutOfFocus +0.08762909696208894 3.740874472348979e-27 BR00118050 CDK9 final orf N22 A549 96 7990 OutOfFocus +0.10046398191007896 5.24627642692231e-27 BR00117006 ANXA1 final orf D23 A549 96 6040 OutOfFocus +0.09461254612546126 8.414805446138496e-27 BR00118050 ALK final orf J13 A549 96 6775 OutOfFocus +0.09499382212315967 1.3381765480686073e-26 BR00118050 PDE3A final orf O19 A549 96 6660 OutOfFocus +0.10342880469603156 2.6822327052879315e-26 BR00117006 IL1B final orf G08 A549 96 5555 OutOfFocus +0.0913453433345443 2.857380673695883e-26 BR00118050 CA5A final orf B02 A549 96 7110 OutOfFocus +0.09551478054506106 3.5418501848963323e-26 BR00118050 SCNN1G final orf O03 A549 96 6485 OutOfFocus +0.09612159431149865 6.661872247163358e-26 BR00118050 ADH1C final orf M23 A549 96 6330 OutOfFocus +0.08839861393563653 8.094741289809693e-26 BR00118050 CACNB4 final orf M01 A549 96 7455 OutOfFocus +0.08117507351277992 8.925431165661761e-26 BR00117006 PLD1 final orf L05 A549 96 8840 OutOfFocus +0.0843193968461025 2.161086725888429e-25 BR00118050 DDR2 final orf M02 A549 96 8070 OutOfFocus +0.11257305128619391 5.847195214635842e-25 BR00117006 DYRK1B final orf G13 A549 96 4445 OutOfFocus +0.08598006644518272 1.2982957395690072e-24 BR00118050 KCNQ2 final orf K01 A549 96 7525 OutOfFocus +0.08240865335404116 2.3677771405920593e-24 BR00118050 ALDH2 final orf P13 A549 96 8095 OutOfFocus +0.0879724462865884 3.1352554997562825e-24 BR00117006 FOXM1 final orf J02 A549 96 7070 OutOfFocus +0.09369102053901351 8.625415751415931e-24 BR00118050 MAPK14 final orf G22 A549 96 6110 OutOfFocus +0.09143573564851298 3.6849535875457346e-23 BR00117006 ICAM1 final orf I08 A549 96 6235 OutOfFocus +0.1068278186533484 1.84528466584207e-22 BR00118050 GRIN2A final orf A05 A549 96 4430 OutOfFocus +0.08669756362306541 2.0155787981103908e-22 BR00118050 GJB4 final orf P08 A549 96 6715 OutOfFocus +0.07558304533892371 2.0536932303959677e-22 BR00117006 ALDH2 final orf P13 A549 96 8835 OutOfFocus +0.09855003817176465 3.1269032492390623e-22 BR00117006 GLRA3 final orf E05 A549 96 5155 OutOfFocus +0.10130663866075422 3.918832925459566e-22 BR00118050 DNMT3A final orf H07 A549 96 4855 OutOfFocus +0.09206967106643836 4.51390087140154e-22 BR00117006 PORCN final orf D22 A549 96 5870 OutOfFocus +0.07666305204704536 6.6583982559758475e-22 BR00118050 ANXA1 final orf N24 A549 96 8395 OutOfFocus +0.0757357811709437 7.363117896959575e-22 BR00117006 PTGIS final orf H13 A549 96 8580 OutOfFocus +0.088042602614041 9.701001759496443e-22 BR00117006 PIK3CG final orf G18 A549 96 6305 OutOfFocus +0.1039715681919147 1.2504238411824175e-21 BR00117006 TNNC1 final orf M18 A549 96 4500 OutOfFocus +0.08794892258579409 1.696883087442129e-21 BR00118050 OPRL1 final orf O16 A549 96 6265 OutOfFocus +0.08651162790697674 2.0489050760007604e-21 BR00118050 CLK1 final orf J17 A549 96 6450 OutOfFocus +0.09121697631765521 2.6706010596735587e-21 BR00117006 BRAF final orf I10 A549 96 5765 OutOfFocus +0.07666097398948025 5.355525813980328e-21 BR00117006 SSTR2 final orf J01 A549 96 8045 OutOfFocus +0.09072851494288918 7.683097030593223e-21 BR00117006 SLC29A1 final orf L20 A549 96 5695 OutOfFocus +0.07855263157894737 8.217447651229262e-21 BR00118050 JAK1 final orf H17 A549 96 7600 OutOfFocus +0.08598885131497637 1.450521234379492e-20 BR00118050 ALDH2 final orf P14 A549 96 6260 OutOfFocus +0.08700745033783401 1.835966549545141e-20 BR00117006 SLC7A11 final orf G24 A549 96 6085 OutOfFocus +0.09625319427014585 1.9548993799598722e-20 BR00118050 SLC7A11 final orf G24 A549 96 4960 OutOfFocus +0.08366437679696245 2.6748294739733596e-20 BR00117006 S1PR2 final orf B06 A549 96 6510 OutOfFocus +0.0855448069266214 6.420588135493487e-20 BR00117006 ERBB2 final orf E21 A549 96 6115 OutOfFocus +0.0811320658430727 7.097174611431725e-20 BR00117006 FLT3 final orf E14 A549 96 6785 OutOfFocus +0.09296729668438866 8.266379087725264e-20 BR00117006 KCNH7 final orf A22 A549 96 5150 OutOfFocus 0.1412223584885435 1.5347399074337912e-83 BR00117006 GPR119 final orf N23 A549 96 9560 Polylobed 0.1289580352969798 6.334085605144917e-75 BR00118050 HDAC3 final orf N21 A549 96 10275 Polylobed 0.13706440244383666 1.9232808882606624e-73 BR00117006 HTR3A final orf J23 A549 96 8910 Polylobed @@ -1479,6 +14709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.12556999463033097 1.2736082878892303e-63 BR00117006 PDPK1 final orf H15 A549 96 9190 Polylobed 0.12087931875957017 1.3753724125456094e-57 BR00117006 CDK4 final orf B21 A549 96 8975 Polylobed 0.12499149054588966 1.9345884325875543e-57 BR00118050 PDE7A final orf J11 A549 96 8380 Polylobed +0.11576191409661334 1.6196592107963696e-55 BR00118050 AURKB final orf L19 A549 96 9430 Polylobed +0.11844786292196419 2.1855784411133435e-54 BR00117006 CHRM2 final orf B03 A549 96 8835 Polylobed +0.1162251655629139 1.077692817626003e-53 BR00117006 ASIC1 final orf L21 A549 96 9060 Polylobed +0.117940863302408 2.4018966024272937e-53 BR00117006 PTK2B final orf N19 A549 96 8725 Polylobed +0.11761684942454932 1.3267910049598717e-51 BR00117006 AURKB final orf L19 A549 96 8490 Polylobed +0.11932869851752533 8.132186079991397e-49 BR00117006 FPR1 final orf D21 A549 96 7805 Polylobed +0.11650235510609609 2.786009298605381e-48 BR00118050 ALDH2 final orf P13 A549 96 8095 Polylobed +0.1028335895172297 1.9954297578517818e-47 BR00117006 BRD4 final orf N17 A549 96 10205 Polylobed +0.11832460732984293 5.502727587371678e-47 BR00118050 PTK2B final orf N19 A549 96 7640 Polylobed +0.10776433118914758 9.27105991171711e-46 BR00117006 PDE7A final orf J11 A549 96 8955 Polylobed +0.1146763185547642 3.1754393882520794e-45 BR00117006 GJB4 final orf H23 A549 96 7825 Polylobed +0.10678766355401266 6.597606839779908e-43 BR00117006 CDK9 final orf H11 A549 96 8545 Polylobed +0.10843401006023515 2.173515236096585e-42 BR00118050 AKR1B1 final orf L17 A549 96 8185 Polylobed +0.10018571051796843 2.6791228868571872e-42 BR00118050 S1PR1 final orf L01 A549 96 9575 Polylobed +0.12197317875311578 1.243833077999769e-39 BR00117006 ANXA1 final orf D23 A549 96 6040 Polylobed +0.0884416476800115 1.2300527834962025e-36 BR00118050 TBXAS1 final orf P23 A549 96 10635 Polylobed +0.10234558209203845 3.660663090072741e-36 BR00118050 GJB4 final orf H23 A549 96 7840 Polylobed +0.09754293820667313 4.1652604416157725e-34 BR00117006 CSF1R final orf J07 A549 96 8135 Polylobed +0.11333899745114698 2.5221725695838884e-33 BR00117006 GHSR final orf C24 A549 96 5885 Polylobed +0.13529290097921787 1.4890751950241415e-32 BR00118050 CSF1R final orf D14 A549 96 4025 Polylobed +0.11153004714227702 2.783902306100325e-32 BR00117006 PORCN final orf D22 A549 96 5870 Polylobed +0.09623886389611336 5.041122028332119e-32 BR00117006 CLK1 final orf J17 A549 96 7840 Polylobed +0.09715648000685669 1.596586141155387e-30 BR00118050 PDPK1 final orf H15 A549 96 7325 Polylobed +0.0987261350437736 2.0596301858872144e-30 BR00117006 FOXM1 final orf J02 A549 96 7070 Polylobed +0.09089860090689848 3.0275491465770465e-30 BR00117006 JAK1 final orf H17 A549 96 8280 Polylobed +0.10095757770288344 3.503094427836641e-30 BR00117006 ERBB2 final orf I20 A549 96 6700 Polylobed +0.10069426272101875 1.921304136125269e-28 BR00117006 MAPK8 final orf I14 A549 96 6350 Polylobed +0.08601949260619002 3.4302067534984417e-28 BR00117006 LPAR1 final orf B05 A549 96 8610 Polylobed +0.11434758076879283 3.9434075018737043e-28 BR00118050 DNMT3A final orf H07 A549 96 4855 Polylobed +0.08957559411945143 1.312063535893945e-27 BR00118050 GAA final orf N15 A549 96 7775 Polylobed +0.09579335793357933 1.826189414630868e-27 BR00118050 ALK final orf J13 A549 96 6775 Polylobed +0.10125917189482492 1.9510859789452073e-27 BR00117006 SIRT2 final orf A07 A549 96 6040 Polylobed +0.09744983380741398 1.967440403036587e-27 BR00118050 FPR1 final orf D21 A549 96 6525 Polylobed +0.08486162246865156 9.302446839290794e-27 BR00118050 ANXA1 final orf N24 A549 96 8395 Polylobed +0.08084855923351052 1.356270195891836e-26 BR00117006 IMPDH1 final orf L13 A549 96 9190 Polylobed +0.09627906976744185 1.9798046716551375e-26 BR00118050 CLK1 final orf J17 A549 96 6450 Polylobed +0.0967600798761471 2.2004162869603458e-26 BR00117006 ASIC1 final orf F12 A549 96 6370 Polylobed +0.09932369411131799 1.2093119623538642e-25 BR00117006 ADRA2B final orf N18 A549 96 5860 Polylobed +0.10025359912556385 1.2126983662301914e-25 BR00117006 BRAF final orf I10 A549 96 5765 Polylobed +0.08159574082396696 3.1010469112263765e-25 BR00117006 GAA final orf N15 A549 96 8550 Polylobed +0.08262719640787201 2.509751557918459e-24 BR00117006 SSTR2 final orf J01 A549 96 8045 Polylobed +0.10371467543725951 2.525049554521787e-24 BR00117006 CYP2A6 final orf A20 A549 96 5095 Polylobed +0.09040708406519274 2.7491661393304037e-24 BR00118050 P3H1 final orf F23 A549 96 6705 Polylobed +0.07839591566206555 4.341422146044657e-24 BR00117006 ALDH2 final orf P13 A549 96 8835 Polylobed +0.09024998085475577 1.1313896130660457e-23 BR00117006 PNLIP final orf L22 A549 96 6545 Polylobed +0.08824816701138409 2.0217194893711582e-23 BR00117006 CA14 final orf N07 A549 96 6785 Polylobed +0.10298003857810199 6.881885011546056e-23 BR00118050 PDE4D final orf B17 A549 96 4855 Polylobed +0.09089919994045684 8.665264044122318e-23 BR00117006 KCNN1 final orf A01 A549 96 6220 Polylobed +0.09411764705882353 1.081781553554708e-22 BR00117006 PTGIS final orf F16 A549 96 5780 Polylobed +0.09838862559241707 1.2318040502996866e-22 BR00118050 PTGIS final orf H13 A549 96 5275 Polylobed +0.09425904094450252 1.8509043080091759e-22 BR00117006 SLC29A1 final orf L20 A549 96 5695 Polylobed +0.07859098172304502 2.2985519146134596e-22 BR00117006 AKR1B1 final orf L17 A549 96 8150 Polylobed +0.10550718199318822 3.0330055365130486e-22 BR00117006 TNNC1 final orf M18 A549 96 4500 Polylobed +0.07811595260576967 4.327228621128017e-22 BR00118050 GPR119 final orf N02 A549 96 8160 Polylobed +0.07579507525471862 5.937684813519862e-22 BR00117006 S1PR1 final orf L01 A549 96 8615 Polylobed +0.0974559686888454 1.5558381964721885e-21 BR00118050 SLC29A1 final orf L20 A549 96 5110 Polylobed +0.0743058933377004 4.587105527962649e-21 BR00117006 PTGIS final orf H13 A549 96 8580 Polylobed +0.09264750099130539 4.862981078957857e-21 BR00118050 UGT1A9 final orf O09 A549 96 5520 Polylobed +0.09687375178204082 5.0316437173806e-21 BR00117006 GABRB2 final orf C06 A549 96 5035 Polylobed +0.09776876267748479 6.374648065796358e-21 BR00118050 IL1B final orf G08 A549 96 4930 Polylobed +0.08409887436629777 1.2317772489691998e-20 BR00117006 ALK final orf J13 A549 96 6555 Polylobed +0.08317689759731241 1.39502533146078e-20 BR00117006 RPL23A final orf I07 A549 96 6690 Polylobed +0.07795124873731503 2.44363958843894e-20 BR00117006 LCK final orf B18 A549 96 7535 Polylobed +0.08819031435853866 2.5054382694698398e-20 BR00117006 BRD4 final orf F14 A549 96 5885 Polylobed +0.0906965970560349 4.2963534912991103e-20 BR00118050 PPAT final orf F11 A549 96 5485 Polylobed +0.08589873651729757 1.7632013518352308e-19 BR00117006 RPL23A final orf G16 A549 96 5920 Polylobed +0.07645096731154102 1.8148766447217098e-19 BR00117006 PARP3 final orf H21 A549 96 7495 Polylobed +0.09381560465082701 2.554795067812495e-19 BR00118050 KCNK1 final orf M15 A549 96 4925 Polylobed +0.09018366910532083 7.493423364195979e-19 BR00117006 PLA2G1B final orf E06 A549 96 5205 Polylobed +0.06734906878150863 1.3245770896687605e-18 BR00118050 BTK final orf N01 A549 96 9210 Polylobed +0.0686626763871731 1.411219898484479e-18 BR00117006 PLD1 final orf L05 A549 96 8840 Polylobed +0.0836424957841484 1.836756535636396e-18 BR00117006 NAMPT final orf L06 A549 96 5930 Polylobed +0.08410503721216997 1.865014069852424e-18 BR00117006 MAPK14 final orf G22 A549 96 5845 Polylobed +0.09683170565523506 2.109595818467487e-18 BR00118050 UGT1A9 final orf E24 A549 96 4400 Polylobed +0.09083187572744829 2.747236158782896e-18 BR00118050 SLC7A11 final orf G24 A549 96 4960 Polylobed +0.07992062838286387 2.797645453964313e-18 BR00117006 DHH final orf E08 A549 96 6425 Polylobed +0.08690902964587349 3.961260906089203e-18 BR00118050 PTGIS final orf F16 A549 96 5380 Polylobed +0.08452713749394478 6.0067578256065304e-18 BR00118050 CTSG final orf J12 A549 96 5630 Polylobed +0.07929243518404265 6.5428861198472585e-18 BR00117006 KRAS final orf D17 A549 96 6390 Polylobed +0.0830411903066155 7.937578131844961e-18 BR00118050 PDE7A final orf F20 A549 96 5795 Polylobed +0.09055275395144677 8.092219516329044e-18 BR00117006 CACNG1 final orf A16 A549 96 4860 Polylobed +0.07539723117988323 8.74619332645684e-18 BR00117006 PARP3 final orf J20 A549 96 7020 Polylobed +0.09619984891724022 1.4521107129790767e-17 BR00118050 IMPDH1 final orf N20 A549 96 4255 Polylobed +0.08495580378790774 2.989382769462118e-17 BR00117006 P3H1 final orf P24 A549 96 5355 Polylobed +0.0785828270000166 4.0948944163515183e-17 BR00118050 MET final orf C08 A549 96 6210 Polylobed +0.07462133840559752 5.4367903925749925e-17 BR00118050 PRKCE final orf J19 A549 96 6825 Polylobed +0.08013519223127459 5.71719239678268e-17 BR00117006 HBB final orf C10 A549 96 5915 Polylobed +0.07653932757370065 5.981531686307683e-17 BR00118050 SCNN1G final orf O03 A549 96 6485 Polylobed +0.0750274969131606 6.150757412447299e-17 BR00117006 PPARD final orf I12 A549 96 6725 Polylobed +0.07422582580549783 7.416800161012831e-17 BR00117006 PRKCB final orf K19 A549 96 6855 Polylobed 0.0905790294483869 6.665221297145715e-22 BR00118050 KCNN4 final orf A06 A549 96 6015 Prometaphase 0.09135313801877794 9.50741114091327e-21 BR00118050 AKR1C1 final orf A24 A549 96 5590 Prometaphase 0.5386395843174303 9.257164366111791e-20 BR00118049 P3H1 final orf P24 A549 96 145 Prometaphase @@ -1489,6 +14809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.060142271992062644 3.5222586432181324e-13 BR00118050 ALDH2 final orf P13 A549 96 8095 Prometaphase 0.2897807987628347 5.786194181535517e-13 BR00118049 PDPK1 final orf H15 A549 96 334 Prometaphase 0.06564834202184985 9.898733594749135e-13 BR00117006 PNLIP final orf L22 A549 96 6545 Prometaphase +0.2191780821917808 1.067077279651124e-12 BR00118049 CLK1 final orf J17 A549 96 584 Prometaphase +0.06881903143585387 1.5415554799825054e-12 BR00117006 GHSR final orf C24 A549 96 5885 Prometaphase +0.06801576291292197 2.6775814067743374e-12 BR00117006 PTK2B final orf J18 A549 96 5900 Prometaphase +0.06729872389183297 5.395515332435609e-12 BR00117006 ADRA2B final orf N18 A549 96 5860 Prometaphase +0.06626297577854671 1.8709733658378046e-11 BR00117006 PTGIS final orf F16 A549 96 5780 Prometaphase +0.08753312071570517 2.1878502167493903e-11 BR00118050 DYRK1B final orf G13 A549 96 3280 Prometaphase +0.3247863247863248 2.560214929759505e-11 BR00118049 IGF1R final orf H05 A549 96 234 Prometaphase +0.06500900698382996 5.4445011850030584e-11 BR00118050 DYRK1B final orf M12 A549 96 5735 Prometaphase +0.05472636815920398 6.899485388490242e-11 BR00117006 MAPK14 final orf G15 A549 96 8040 Prometaphase +0.06101452070029418 1.0331873827953782e-10 BR00118050 GHSR final orf C24 A549 96 6335 Prometaphase +0.05947565543071161 1.0996526154026741e-10 BR00117006 COMT final orf P09 A549 96 6675 Prometaphase +0.2606281450633351 1.2637164699981843e-10 BR00118049 FLT3 final orf E14 A549 96 340 Prometaphase +0.29944974037045646 1.354988965375582e-10 BR00118049 CDK9 final orf H11 A549 96 253 Prometaphase +0.05805832403502468 1.4857782159718231e-10 BR00118050 SLCO2B1 final orf A02 A549 96 6900 Prometaphase +0.05019847414272334 1.628624894045483e-10 BR00117006 PDPK1 final orf H15 A549 96 9190 Prometaphase +0.057326088482618894 1.8235380768688267e-10 BR00117006 PARP3 final orf J20 A549 96 7020 Prometaphase +0.3064156206415621 2.2765182038709494e-10 BR00118049 S1PR4 final orf M17 A549 96 239 Prometaphase +0.26435530886874575 2.523303644047623e-10 BR00118049 AURKB final orf L19 A549 96 317 Prometaphase +0.0715177926275283 2.6055548254946087e-10 BR00118050 GRIN2A final orf A05 A549 96 4430 Prometaphase +0.07060274488452016 2.7331652944817323e-10 BR00118050 CATSPER4 final orf D24 A549 96 4540 Prometaphase +0.06799730165743238 3.206803912103961e-10 BR00117006 CACNG1 final orf A16 A549 96 4860 Prometaphase +0.2191511387163561 3.318182784790261e-10 BR00118049 PTK2B final orf J18 A549 96 460 Prometaphase +0.04687723468542018 3.506801190401415e-10 BR00117006 BRD4 final orf N17 A549 96 10205 Prometaphase +0.23028676449137955 3.625827614132451e-10 BR00118049 AKT1 final orf J16 A549 96 415 Prometaphase +0.059468170829975825 5.836096307995716e-10 BR00118050 CCR1 final orf F24 A549 96 6205 Prometaphase +0.2492836676217765 6.25242024615595e-10 BR00118049 MAPK8 final orf I14 A549 96 349 Prometaphase +0.060470828714932666 9.627976610776016e-10 BR00118050 AGER final orf H18 A549 96 5845 Prometaphase +0.05687626543698038 2.057372866452516e-09 BR00117006 AKR1C1 final orf I01 A549 96 6380 Prometaphase +0.04586055298581263 2.2250743980203428e-09 BR00117006 EZH2 final orf D03 A549 96 9780 Prometaphase +0.06884445601048654 2.344664336421393e-09 BR00118050 FLT3 final orf K13 A549 96 4320 Prometaphase +0.07410722566479525 2.441674039062815e-09 BR00118050 LPAR1 final orf B05 A549 96 3730 Prometaphase +0.06298180524361902 2.7622017439221225e-09 BR00118050 CACNG1 final orf A16 A549 96 5135 Prometaphase +0.04811444813097659 4.926196529332829e-09 BR00117006 CDK9 final orf H11 A549 96 8545 Prometaphase +0.23380281690140844 6.411408112278683e-09 BR00118049 FLT3 final orf K13 A549 96 355 Prometaphase +0.25833333333333336 6.433425280807143e-09 BR00118049 PDE7A final orf J11 A549 96 288 Prometaphase +0.05380228674994238 7.713577347171145e-09 BR00117006 CYP2A6 final orf A15 A549 96 6670 Prometaphase +0.23229092066523435 7.853473149597223e-09 BR00118049 MAPK8 final orf I13 A549 96 354 Prometaphase +0.06097241822159503 7.99519810608698e-09 BR00118050 PAK4 final orf G10 A549 96 5175 Prometaphase +0.04884340516985981 1.586443221890519e-08 BR00117006 FPR1 final orf D21 A549 96 7805 Prometaphase +0.05624644421708139 1.6044509108751756e-08 BR00118050 PDPK1 final orf D06 A549 96 5860 Prometaphase +0.2624228598169109 1.6427257415492118e-08 BR00118049 CTSG final orf F19 A549 96 261 Prometaphase +0.06725266675822918 2.0762496851398605e-08 BR00117006 MMP2 final orf F06 A549 96 4050 Prometaphase +0.22943394250405824 2.18344013410274e-08 BR00118049 S1PR4 final orf K18 A549 96 339 Prometaphase +0.2466219364458112 2.2205299124905442e-08 BR00118049 PRKCE final orf J19 A549 96 294 Prometaphase +0.22256156897971405 2.2375926737065516e-08 BR00118049 CSF1R final orf J07 A549 96 365 Prometaphase +0.05631936113064676 2.5352708764754643e-08 BR00118050 AKT1 final orf F15 A549 96 5715 Prometaphase +0.06367534765043159 2.7721670272804228e-08 BR00117006 DYRK1B final orf G13 A549 96 4445 Prometaphase +0.054306808859721084 3.098458694478422e-08 BR00118050 PTPN2 final orf I02 A549 96 6095 Prometaphase +0.05590497768080555 3.9456309956933224e-08 BR00118050 PLK1 final orf L11 A549 96 5645 Prometaphase +0.2168427187295112 4.485856694586527e-08 BR00118049 AKT1 final orf F15 A549 96 370 Prometaphase +0.05097021463084641 5.1134281425718826e-08 BR00117006 AKT1 final orf F15 A549 96 6710 Prometaphase +0.048483274958911055 6.352501923564427e-08 BR00117006 ALDH2 final orf P14 A549 96 7325 Prometaphase +0.05611561913082338 6.647669263880398e-08 BR00118050 CACNB4 final orf A18 A549 96 5460 Prometaphase +0.06316482979484629 7.07920345700762e-08 BR00117006 DYRK1B final orf M12 A549 96 4280 Prometaphase +0.04651990473772652 7.550274985535669e-08 BR00117006 GRIN2A final orf A05 A549 96 7875 Prometaphase +0.06473107651758504 8.010084504220473e-08 BR00118050 HSD11B1 final orf G23 A549 96 4050 Prometaphase +0.04833398712438474 8.230797973989536e-08 BR00118050 GRIN2A final orf I24 A549 96 7270 Prometaphase +0.15893331634695884 8.259307977874671e-08 BR00118049 JAK1 final orf H17 A549 96 664 Prometaphase +0.05912779422272124 8.286572698485877e-08 BR00117006 DCK final orf L18 A549 96 4850 Prometaphase +0.05002363136883692 9.712058548204093e-08 BR00118050 GJB4 final orf P08 A549 96 6715 Prometaphase +0.05076687116564417 1.0014743274102869e-07 BR00117006 KCNK1 final orf M15 A549 96 6520 Prometaphase +0.05374758021103709 1.1089720473380313e-07 BR00118050 SLC29A1 final orf N03 A549 96 5775 Prometaphase +0.04990851599684407 1.1957238720582512e-07 BR00118050 FFAR4 final orf I16 A549 96 6660 Prometaphase +0.11986584107327142 1.2558278816424262e-07 BR00118049 SLCO2B1 final orf A02 A549 96 1140 Prometaphase +0.053344602708851024 1.5424632434049338e-07 BR00118050 CA14 final orf N07 A549 96 5730 Prometaphase +0.05998599509100279 1.559804134365242e-07 BR00118050 KRAS final orf F08 A549 96 4540 Prometaphase +0.0541607558073174 1.6613042068051557e-07 BR00117006 TBXAS1 final orf J24 A549 96 5535 Prometaphase +0.2381929404612637 1.6925001650601506e-07 BR00118049 PDE3A final orf O19 A549 96 283 Prometaphase +0.05087350365783287 1.9020938980610113e-07 BR00118050 PIK3CG final orf G18 A549 96 6225 Prometaphase +0.057894100333097984 1.9171790481894043e-07 BR00118050 CDK7 final orf K06 A549 96 4795 Prometaphase +0.043588821252458956 2.2862470358272474e-07 BR00118050 ANXA1 final orf N24 A549 96 8395 Prometaphase +0.04867987749481055 3.392692590296287e-07 BR00117006 ALK final orf J13 A549 96 6555 Prometaphase +0.04769495978641516 3.431046784303957e-07 BR00118050 PRKCE final orf J19 A549 96 6825 Prometaphase +0.04981209274054119 3.696156551368835e-07 BR00117006 KCNN1 final orf A01 A549 96 6220 Prometaphase +0.06423652912630241 4.436329354338068e-07 BR00117006 JAK1 final orf D18 A549 96 3695 Prometaphase +0.041250650429625065 4.493960706155737e-07 BR00117006 CDK4 final orf B21 A549 96 8975 Prometaphase +0.050789885870209446 4.8026574609526e-07 BR00117006 CATSPER4 final orf D24 A549 96 5895 Prometaphase +0.050689907951770266 5.836496387366424e-07 BR00117006 MAPK14 final orf G22 A549 96 5845 Prometaphase +0.04923076923076923 6.298117989049576e-07 BR00117006 SCNN1G final orf A04 A549 96 6175 Prometaphase +0.042618973901214136 7.260508921731286e-07 BR00117006 RPL3 final orf G09 A549 96 8140 Prometaphase +0.04667860084936317 7.320215642801921e-07 BR00117006 FLT3 final orf E14 A549 96 6785 Prometaphase +0.04779375724061864 7.675096484974182e-07 BR00118050 ATP5F1D final orf G14 A549 96 6435 Prometaphase +0.1387434554973822 7.897925795916008e-07 BR00118049 IMPDH1 final orf L13 A549 96 764 Prometaphase +0.04060910160991149 8.837990070783497e-07 BR00117006 ALDH2 final orf P13 A549 96 8835 Prometaphase +0.049852185495429614 9.833181941595832e-07 BR00118050 MMP2 final orf F06 A549 96 5810 Prometaphase +0.051826922758139576 1.076106628944469e-06 BR00117006 P3H1 final orf P24 A549 96 5355 Prometaphase +0.04813978648827626 1.2002187368124248e-06 BR00117006 GUCY1B1 final orf J08 A549 96 6160 Prometaphase +0.039624724061810154 1.323715487381074e-06 BR00117006 ASIC1 final orf L21 A549 96 9060 Prometaphase +0.04327698623690999 1.4312215811072926e-06 BR00117006 LCK final orf B18 A549 96 7535 Prometaphase +0.1565217391304348 1.456454867734958e-06 BR00118049 CDC25A final orf I19 A549 96 575 Prometaphase 0.16355874109113216 2.9356614631982284e-105 BR00117006 CDK4 final orf B21 A549 96 8975 SmallIrregular 0.14833588705072767 3.743973435254715e-92 BR00117006 GPR119 final orf N23 A549 96 9560 SmallIrregular 0.15534825870646765 4.988139267458592e-85 BR00118050 BRD4 final orf N17 A549 96 8040 SmallIrregular @@ -1499,6 +14909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.14375384615384615 1.3561875105928582e-73 BR00118050 HTR3A final orf J23 A549 96 8125 SmallIrregular 0.15491784087756294 9.651946949022943e-64 BR00117006 ANXA1 final orf D23 A549 96 6040 SmallIrregular 0.11589193204782983 1.4908044824483664e-60 BR00118050 HDAC3 final orf N21 A549 96 10275 SmallIrregular +0.11961987350786661 8.466129553139605e-55 BR00117006 PTK2B final orf N19 A549 96 8725 SmallIrregular +0.11721854304635762 1.3059248581608315e-54 BR00117006 ASIC1 final orf L21 A549 96 9060 SmallIrregular +0.1245163781904996 2.912142305706372e-53 BR00117006 GJB4 final orf H23 A549 96 7825 SmallIrregular +0.12578534031413613 4.653527293187919e-53 BR00118050 PTK2B final orf N19 A549 96 7640 SmallIrregular +0.111167368842799 5.579327425700986e-52 BR00118050 S1PR1 final orf L01 A549 96 9575 SmallIrregular +0.11689099377817543 1.981714922339772e-50 BR00118050 ANXA1 final orf N24 A549 96 8395 SmallIrregular +0.12124898421572591 2.166668766688031e-50 BR00117006 FPR1 final orf D21 A549 96 7805 SmallIrregular +0.11335102492184657 7.782291361501704e-50 BR00117006 CHRM2 final orf B03 A549 96 8835 SmallIrregular +0.1129179602551699 1.5443255670508522e-49 BR00117006 ALDH2 final orf P13 A549 96 8835 SmallIrregular +0.10944953199106769 6.095871758282482e-47 BR00117006 HTR3A final orf J23 A549 96 8910 SmallIrregular +0.10851965962059591 3.147189415388161e-44 BR00117006 CDK9 final orf H11 A549 96 8545 SmallIrregular +0.10857361685164535 5.280102266217299e-44 BR00117006 AURKB final orf L19 A549 96 8490 SmallIrregular +0.10772377870463179 8.188782102065774e-43 BR00118050 PDE7A final orf J11 A549 96 8380 SmallIrregular +0.09651386913307586 8.118145880661095e-42 BR00117006 BRD4 final orf N17 A549 96 10205 SmallIrregular +0.10159494323019212 1.026531220217692e-41 BR00117006 PDPK1 final orf H15 A549 96 9190 SmallIrregular +0.11937984496124031 1.9379933611615686e-40 BR00118050 CLK1 final orf J17 A549 96 6450 SmallIrregular +0.10846413587409418 5.788164708979454e-38 BR00118050 PDPK1 final orf H15 A549 96 7325 SmallIrregular +0.11315898222641477 7.64308450907222e-38 BR00118050 P3H1 final orf F23 A549 96 6705 SmallIrregular +0.10259726108880916 9.345478882973204e-38 BR00117006 CSF1R final orf J07 A549 96 8135 SmallIrregular +0.11247232472324724 1.0096824943219768e-37 BR00118050 ALK final orf J13 A549 96 6775 SmallIrregular +0.09941585015133557 1.6330054349283298e-37 BR00117006 S1PR1 final orf L01 A549 96 8615 SmallIrregular +0.08948977116891565 1.680048259482026e-37 BR00118050 TBXAS1 final orf P23 A549 96 10635 SmallIrregular +0.11023622720640931 1.3132613834848842e-36 BR00118050 ASIC1 final orf L21 A549 96 6840 SmallIrregular +0.12281850824266127 1.0517567798036636e-35 BR00117006 AKR1C1 final orf A24 A549 96 5360 SmallIrregular +0.10132497872251821 1.8795633275244084e-35 BR00118050 GJB4 final orf H23 A549 96 7840 SmallIrregular +0.10218854346468885 3.061244513734451e-35 BR00117006 BTK final orf N01 A549 96 7655 SmallIrregular +0.13479192299972947 2.1585166457220665e-34 BR00117006 DYRK1B final orf M12 A549 96 4280 SmallIrregular +0.09679159301881828 8.47868173218127e-34 BR00118050 AKR1B1 final orf L17 A549 96 8185 SmallIrregular +0.09674962582644081 3.0797502257219454e-33 BR00117006 SSTR2 final orf J01 A549 96 8045 SmallIrregular +0.097400864339108 1.5214335960285253e-32 BR00118050 GAA final orf N15 A549 96 7775 SmallIrregular +0.09485294117647058 2.348380045517626e-32 BR00117006 F10 final orf C09 A549 96 8160 SmallIrregular +0.09753168779186124 1.9521576763282077e-31 BR00117006 PARP3 final orf H21 A549 96 7495 SmallIrregular +0.0912025550678271 2.0644730883248394e-31 BR00117006 GAA final orf N15 A549 96 8550 SmallIrregular +0.6559754369390647 6.1461656015696795e-30 BR00118049 P3H1 final orf P24 A549 96 145 SmallIrregular +0.09928896133050881 1.9953383898713653e-29 BR00117006 CYP3A4 final orf K22 A549 96 6755 SmallIrregular +0.08753844429073698 3.546407398843588e-29 BR00117006 LPAR1 final orf B05 A549 96 8610 SmallIrregular +0.09347901583128697 4.521294368714368e-29 BR00117006 LCK final orf B18 A549 96 7535 SmallIrregular +0.08860538829107811 9.278222021167699e-29 BR00117006 JAK1 final orf H17 A549 96 8280 SmallIrregular +0.09974885994818454 6.4231045477275325e-28 BR00117006 MAPK8 final orf I14 A549 96 6350 SmallIrregular +0.09830265139718858 2.3680234090817567e-27 BR00117006 KRAS final orf D17 A549 96 6390 SmallIrregular +0.10052335657174367 4.613530941555612e-27 BR00118050 CLK1 final orf D08 A549 96 6045 SmallIrregular +0.08514962146358734 3.4340100160028017e-25 BR00117006 CLK1 final orf J17 A549 96 7840 SmallIrregular +0.07836239756101614 4.641595835433746e-25 BR00118050 BTK final orf N01 A549 96 9210 SmallIrregular +0.0967000611022634 4.814659944876368e-24 BR00118050 PDE7A final orf F20 A549 96 5795 SmallIrregular +0.07701184398167135 1.5572356362646018e-23 BR00117006 PDE7A final orf J11 A549 96 8955 SmallIrregular +0.09345281205343554 1.9920291016923133e-22 BR00118050 SLC29A1 final orf N03 A549 96 5775 SmallIrregular +0.08409234915174815 8.494356426942166e-22 BR00117006 USP1 final orf E12 A549 96 6935 SmallIrregular +0.08531410200672031 3.1804966182524836e-21 BR00117006 ALK final orf J13 A549 96 6555 SmallIrregular +0.08355780954073737 4.592683935076011e-21 BR00117006 FLT3 final orf E14 A549 96 6785 SmallIrregular +0.0945945945945946 1.3890452143180406e-20 BR00117006 KCNH7 final orf O07 A549 96 5180 SmallIrregular +0.08316606270520671 1.486578635611931e-20 BR00117006 RPL23A final orf I07 A549 96 6690 SmallIrregular +0.08382415661227957 2.111080904835402e-20 BR00118050 FPR1 final orf D21 A549 96 6525 SmallIrregular +0.08742231612629349 3.639188649291216e-20 BR00117006 RPL23A final orf G16 A549 96 5920 SmallIrregular +0.07086665247415411 9.426803123897525e-20 BR00117006 PLD1 final orf L05 A549 96 8840 SmallIrregular +0.09253185337701972 1.7429661541218436e-19 BR00117006 CDK9 final orf N22 A549 96 5115 SmallIrregular +0.08479790009181148 7.822386093842254e-19 BR00117006 PORCN final orf D22 A549 96 5870 SmallIrregular +0.08136377746420602 8.864734428156025e-19 BR00117006 ASIC1 final orf F12 A549 96 6370 SmallIrregular +0.08517705634149379 1.4489195844045217e-18 BR00118050 DYRK1B final orf M12 A549 96 5735 SmallIrregular +0.09430936028812739 3.503827701158678e-18 BR00118050 BRD4 final orf F14 A549 96 4585 SmallIrregular +0.08356256100295742 3.536986692942259e-18 BR00117006 MAPK14 final orf G22 A549 96 5845 SmallIrregular +0.08469460227272728 5.2218714299256914e-18 BR00118050 CTSG final orf J12 A549 96 5630 SmallIrregular +0.07721750808796216 7.267927999461562e-18 BR00118050 GJB4 final orf P08 A549 96 6715 SmallIrregular +0.08924949290060852 1.680371262404759e-17 BR00118050 IL1B final orf G08 A549 96 4930 SmallIrregular +0.08900574856079717 2.0707502513196612e-17 BR00118050 KCNK1 final orf M15 A549 96 4925 SmallIrregular +0.07102962336170487 3.897324562023074e-17 BR00118050 PRKCE final orf L14 A549 96 7615 SmallIrregular +0.07806388551676206 4.607879127197372e-17 BR00117006 AVPR1A final orf D07 A549 96 6260 SmallIrregular +0.06742076135037064 1.4690442091694576e-16 BR00117006 AKR1B1 final orf L17 A549 96 8150 SmallIrregular +0.06741293532338309 2.6412446372367017e-16 BR00117006 DNMT3A final orf H07 A549 96 8040 SmallIrregular +0.07047655716140892 2.938761516860867e-16 BR00117006 ALDH2 final orf P14 A549 96 7325 SmallIrregular +0.0825187969924812 3.56423052824399e-16 BR00118050 CYP1A2 final orf N12 A549 96 5320 SmallIrregular +0.10492289199669537 3.5766022244747324e-16 BR00118050 DYRK1B final orf G13 A549 96 3280 SmallIrregular +0.06991210277214334 3.9075070191754323e-16 BR00117006 ATP5F1D final orf G14 A549 96 7395 SmallIrregular +0.09338155625753483 8.151019585697752e-16 BR00117006 MMP2 final orf F06 A549 96 4050 SmallIrregular +0.07304966968324758 8.380237790769081e-16 BR00118050 GABRB2 final orf C06 A549 96 6615 SmallIrregular +0.07292545567291173 1.1964087232985869e-15 BR00118050 GUCY1B1 final orf J08 A549 96 6580 SmallIrregular +0.07786370845512905 1.8420864384415964e-15 BR00117006 SLC29A1 final orf L20 A549 96 5695 SmallIrregular +0.06855319869333855 2.139974740505141e-15 BR00117006 AGER final orf H09 A549 96 7315 SmallIrregular +0.07133031962742396 4.044707132112074e-15 BR00117006 VEGFA final orf B09 A549 96 6625 SmallIrregular +0.07174749807544265 5.879228843864951e-15 BR00117006 P3H1 final orf F23 A549 96 6495 SmallIrregular +0.06967799245231449 6.498440422845272e-15 BR00117006 PRKCB final orf K19 A549 96 6855 SmallIrregular +0.07959363889082785 8.824583017613297e-15 BR00117006 PLA2G1B final orf E06 A549 96 5205 SmallIrregular +0.07430939722549049 1.9319294540475624e-14 BR00118050 ALK final orf H12 A549 96 5830 SmallIrregular +0.07708576147417379 2.349938063722077e-14 BR00118050 PTGIS final orf F16 A549 96 5380 SmallIrregular +0.08082051282051282 2.8707563185524795e-14 BR00117006 AKT1 final orf J16 A549 96 4875 SmallIrregular +0.07550021532991431 3.7508965813805513e-14 BR00118050 UGT1A9 final orf O09 A549 96 5520 SmallIrregular +0.07323704333050128 3.813637649276505e-14 BR00117006 BRD4 final orf F14 A549 96 5885 SmallIrregular +0.06745457479234673 4.4791567573115165e-14 BR00117006 S1PR4 final orf K18 A549 96 6880 SmallIrregular +0.06421841720240644 4.486702805992832e-14 BR00117006 TUBB4B final orf E07 A549 96 7595 SmallIrregular +0.06497812403249388 5.39210932792921e-14 BR00117006 MAPK8 final orf I13 A549 96 7380 SmallIrregular +0.06529907803315274 8.176402896404406e-14 BR00117006 TUBB3 final orf K05 A549 96 7220 SmallIrregular 0.13557434563229265 3.85444467685476e-39 BR00117023 AKR1C1 final orf A24 U2OS 48 4830 ADCCM 0.10541783323149641 2.7495246092585728e-27 BR00117023 DHH final orf G05 U2OS 48 5540 ADCCM 0.11109411417268465 8.73401025150612e-24 BR00117023 PTGIS final orf F16 U2OS 48 4340 ADCCM @@ -1509,6 +15009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.11069989392336758 7.873273892299588e-20 BR00117023 KRAS final orf D17 U2OS 48 3635 ADCCM 0.11071297771039698 9.88954957024481e-19 BR00117023 KRAS final orf F08 U2OS 48 3425 ADCCM 0.0875 1.5530347245107422e-18 BR00117023 CDC25A final orf M04 U2OS 48 5440 ADCCM +0.10274350113559723 2.0062127662553026e-18 BR00117022 PTK2B final orf N19 U2OS 48 3915 ADCCM +0.09272467333843136 3.4072577347557412e-18 BR00117023 CACNG1 final orf E23 U2OS 48 4750 ADCCM +0.09246119733924613 3.4210295326848253e-17 BR00117023 CACNB4 final orf A18 U2OS 48 4510 ADCCM +0.095205236607784 4.173964266890751e-17 BR00117022 CYP2A6 final orf A20 U2OS 48 4220 ADCCM +0.08950546438918532 6.28164433112795e-17 BR00117022 PTGIS final orf H13 U2OS 48 4730 ADCCM +0.09151672106747115 9.346871173663591e-17 BR00117023 OPRL1 final orf A23 U2OS 48 4475 ADCCM +0.09071199557014363 2.088814007645753e-16 BR00117022 AKR1C1 final orf A24 U2OS 48 4455 ADCCM +0.07866120205653217 4.3807416852297024e-16 BR00117023 HSP90AB1 final orf P01 U2OS 48 5815 ADCCM +0.07854432282269459 4.495372297225819e-15 BR00117023 P3H1 final orf P24 U2OS 48 5455 ADCCM +0.07612175922412417 2.2739822061933053e-14 BR00117022 NTRK1 final orf P02 U2OS 48 5530 ADCCM +0.0935463356118738 2.9424347952028115e-14 BR00117022 ABL1 final orf C01 U2OS 48 3625 ADCCM +0.08430762748978585 3.0414012316063796e-14 BR00117023 HTR2C final orf M06 U2OS 48 4455 ADCCM +0.07786407766990291 5.350856456368819e-14 BR00117022 CACNG1 final orf A16 U2OS 48 5150 ADCCM +0.08018526497013298 6.332925279768439e-14 BR00117023 DYRK1B final orf M12 U2OS 48 4810 ADCCM +0.08283098387761939 1.3757391579682456e-13 BR00117023 SIRT2 final orf A07 U2OS 48 4405 ADCCM +0.07607306138754494 1.5004231002598024e-13 BR00117022 KCNN1 final orf A01 U2OS 48 5200 ADCCM +0.08159837387488818 2.728986165988588e-13 BR00117023 CYP2A6 final orf A20 U2OS 48 4440 ADCCM +0.07839831401475238 4.2026447381326787e-13 BR00117023 PDPK1 final orf D06 U2OS 48 4745 ADCCM +0.07643145156332357 5.193661757536123e-13 BR00117022 IL1B final orf E15 U2OS 48 4940 ADCCM +0.07716371220020855 7.773847132197615e-13 BR00117022 P2RY12 final orf B24 U2OS 48 4795 ADCCM +0.07485742383864637 1.1406358455681675e-12 BR00117023 ABL1 final orf C01 U2OS 48 5005 ADCCM +0.07308739692558282 1.9201889333766435e-12 BR00117023 CHRM3 final orf A11 U2OS 48 5170 ADCCM +0.07880395297183451 3.5173241277012372e-12 BR00117022 PRKCE final orf L14 U2OS 48 4335 ADCCM +0.07434907302495944 4.1076725518584566e-12 BR00117023 TUBB final orf E19 U2OS 48 4855 ADCCM +0.06788511749347259 6.2395596782757325e-12 BR00117022 HSP90AB1 final orf P01 U2OS 48 5745 ADCCM +0.07940106979248446 7.734565031014e-12 BR00117023 FGF1 final orf F22 U2OS 48 4145 ADCCM +0.07303584512201995 1.1537358586620171e-11 BR00117023 HTR2C final orf G21 U2OS 48 4840 ADCCM +0.06965908756967432 1.1897234584565846e-11 BR00117023 KDR final orf O02 U2OS 48 5315 ADCCM +0.07434270464567633 1.2506273450252516e-11 BR00117023 CATSPER4 final orf D24 U2OS 48 4660 ADCCM +0.07145528035469453 1.678111520511453e-11 BR00117022 PAK4 final orf M19 U2OS 48 4970 ADCCM +0.06847585944915274 2.615916431754453e-11 BR00117023 S1PR1 final orf L01 U2OS 48 5335 ADCCM +0.06996960927044614 3.354850987139568e-11 BR00117022 MET final orf C03 U2OS 48 5050 ADCCM +0.07039198405543405 3.669097798191038e-11 BR00117023 HRH4 final orf O06 U2OS 48 4975 ADCCM +0.06667927591397341 4.055428541081564e-11 BR00117023 HPGDS final orf O24 U2OS 48 5520 ADCCM +0.07050544604470403 4.136774756328774e-11 BR00117023 PAK1 final orf L12 U2OS 48 4940 ADCCM +0.06766355140186917 4.5310198258857275e-11 BR00117023 S100B final orf M20 U2OS 48 5350 ADCCM +0.07387936909447006 6.144412860254431e-11 BR00117023 HTR3A final orf H24 U2OS 48 4420 ADCCM +0.07038959160624385 6.889506960840642e-11 BR00117022 BAX final orf K17 U2OS 48 4850 ADCCM +0.06927710843373494 8.200798342860698e-11 BR00117022 GHSR final orf C24 U2OS 48 4980 ADCCM +0.0694918996379936 9.897516297174548e-11 BR00117022 GPR55 final orf H16 U2OS 48 4900 ADCCM +0.08354367907728628 1.1613573742089545e-10 BR00117022 PTK2B final orf J18 U2OS 48 3365 ADCCM +0.07038988408851422 1.2114368162676336e-10 BR00117023 GHSR final orf C24 U2OS 48 4745 ADCCM +0.07373052239722354 1.2587918705417194e-10 BR00117022 CCR1 final orf F24 U2OS 48 4310 ADCCM +0.07258992687889297 1.3678850133912413e-10 BR00117022 HTR2C final orf G21 U2OS 48 4420 ADCCM +0.06906172138644463 1.431615392807627e-10 BR00117023 FPR1 final orf D21 U2OS 48 4875 ADCCM +0.06634980988593156 1.729963561252731e-10 BR00117023 KCNN1 final orf O10 U2OS 48 5260 ADCCM +0.08376327769347497 1.7802306399315643e-10 BR00117023 PTK2B final orf J18 U2OS 48 3295 ADCCM +0.06777065180426525 1.9687969599864156e-10 BR00117023 UGT1A9 final orf E24 U2OS 48 4995 ADCCM +0.0703225806451613 2.0279027055892611e-10 BR00117023 ATM final orf C04 U2OS 48 4650 ADCCM +0.06789806929147903 2.615898471855153e-10 BR00117023 FPR1 final orf L04 U2OS 48 4920 ADCCM +0.07107779267962624 2.9960197535868354e-10 BR00117023 CCR1 final orf F24 U2OS 48 4460 ADCCM +0.0721865189645412 3.1757922335234965e-10 BR00117022 PTGIS final orf F16 U2OS 48 4320 ADCCM +0.06783282180777832 3.188567479596166e-10 BR00117023 TUBB3 final orf G06 U2OS 48 4880 ADCCM +0.072046783625731 4.535581367861149e-10 BR00117023 CA5A final orf B23 U2OS 48 4275 ADCCM +0.0629695885509839 4.669340655495969e-10 BR00117023 CDK2 final orf L03 U2OS 48 5590 ADCCM +0.06958424507658643 4.834333072050405e-10 BR00117023 CYP1A2 final orf F21 U2OS 48 4570 ADCCM +0.065625 5.234659024952553e-10 BR00117023 TUBB3 final orf K05 U2OS 48 5120 ADCCM +0.06835668565098199 5.4428628502728e-10 BR00117023 HDAC3 final orf N06 U2OS 48 4695 ADCCM +0.0710801393728223 7.04737640946436e-10 BR00117022 HDAC3 final orf N06 U2OS 48 4305 ADCCM +0.06272727272727273 7.891971415938575e-10 BR00117022 DDR2 final orf M02 U2OS 48 5500 ADCCM +0.06313140062230593 1.0555090047024108e-09 BR00117022 KCNH7 final orf O07 U2OS 48 5345 ADCCM +0.06629206323138338 1.0617060846706513e-09 BR00117023 PARP3 final orf H21 U2OS 48 4835 ADCCM +0.06056156947398495 1.1587870621725556e-09 BR00117023 ICAM1 final orf I15 U2OS 48 5780 ADCCM +0.06279737647718886 1.1991914725302698e-09 BR00117022 GHSR final orf A17 U2OS 48 5370 ADCCM +0.0680896305539398 1.2520680672456121e-09 BR00117023 PRKCE final orf L14 U2OS 48 4550 ADCCM +0.0672961117925696 1.3154268361447983e-09 BR00117023 CACNG1 final orf A16 U2OS 48 4645 ADCCM +0.06869226234448182 1.3883261191979125e-09 BR00117022 UGT1A9 final orf E24 U2OS 48 4455 ADCCM +0.06772046034580174 1.7060648859739698e-09 BR00117023 P2RY12 final orf B24 U2OS 48 4535 ADCCM +0.0704194049141427 1.7564748373627982e-09 BR00117022 KRAS final orf D17 U2OS 48 4190 ADCCM +0.06583928520553409 1.8883130819774825e-09 BR00117023 PTGIS final orf H13 U2OS 48 4775 ADCCM +0.06734712577089223 2.545840052681859e-09 BR00117022 CYP2A6 final orf A15 U2OS 48 4505 ADCCM +0.06543175363792965 2.9972656015573906e-09 BR00117022 CSF1R final orf D14 U2OS 48 4735 ADCCM +0.06494623655913978 5.9951514748803665e-09 BR00117023 AKT1 final orf F15 U2OS 48 4650 ADCCM +0.06618707397950808 6.350497202043981e-09 BR00117023 LYN final orf C20 U2OS 48 4450 ADCCM +0.06563192904656319 7.2250130066185155e-09 BR00117023 GHSR final orf A17 U2OS 48 4510 ADCCM +0.06540600667408232 8.806204927873395e-09 BR00117022 AKT1 final orf F15 U2OS 48 4495 ADCCM +0.061420239411114505 9.643395907936305e-09 BR00117023 CYP3A4 final orf K09 U2OS 48 5050 ADCCM +0.06482455055253175 1.0676972833557526e-08 BR00117023 AVPR1A final orf H22 U2OS 48 4515 ADCCM +0.06346086605459611 1.078108222721506e-08 BR00117023 DCK final orf D05 U2OS 48 4710 ADCCM +0.060174789203673515 1.5714004948667126e-08 BR00117022 HBB final orf C10 U2OS 48 5130 ADCCM +0.05728880313337768 1.7233745868253262e-08 BR00117022 VEGFA final orf P18 U2OS 48 5630 ADCCM +0.059352558445054486 2.3216306484014613e-08 BR00117022 CACNA2D3 final orf L02 U2OS 48 5165 ADCCM +0.06594837826766432 2.3488875154309686e-08 BR00117023 KCNH7 final orf A22 U2OS 48 4190 ADCCM +0.058914914704502115 2.5875497915679397e-08 BR00117023 PLD1 final orf D10 U2OS 48 5215 ADCCM +0.05633697934929738 3.111797060450365e-08 BR00117023 ADH1C final orf O04 U2OS 48 5640 ADCCM +0.061109670237635506 3.57478795368597e-08 BR00117022 PAK1 final orf L09 U2OS 48 4765 ADCCM +0.05971838589601069 4.294014161232265e-08 BR00117023 KCNJ1 final orf E22 U2OS 48 4925 ADCCM +0.057060865475375463 6.402915173807143e-08 BR00117022 OPRL1 final orf O16 U2OS 48 5270 ADCCM +0.056646727278176504 6.858430998867948e-08 BR00117022 ITGB2 final orf B12 U2OS 48 5325 ADCCM +0.056279453820437426 7.801330442894666e-08 BR00117023 CHRM3 final orf A10 U2OS 48 5365 ADCCM 0.5493927705573842 0.0 BR00117023 ADH1C final orf O04 U2OS 48 5640 Anaphase 0.5420955882352941 0.0 BR00117023 CDC25A final orf M04 U2OS 48 5440 Anaphase 0.5436988456135682 0.0 BR00117023 CDK7 final orf K06 U2OS 48 5015 Anaphase @@ -1519,6 +15109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.4850355909361973 0.0 BR00117023 KCNN4 final orf A06 U2OS 48 4565 Anaphase 0.5239924619639176 0.0 BR00117023 SLC7A11 final orf A03 U2OS 48 4780 Anaphase 0.545774121731889 0.0 BR00117023 TUBB3 final orf G06 U2OS 48 4880 Anaphase +0.58125 0.0 BR00117023 TUBB3 final orf K05 U2OS 48 5120 Anaphase +0.5272903778913395 0.0 BR00117023 TUBB4B final orf E04 U2OS 48 4225 Anaphase +0.20393931102772567 7.596029337072316e-88 BR00117023 LYN final orf M05 U2OS 48 4800 Anaphase +0.2042400727905171 3.3599073505017077e-73 BR00117022 LYN final orf M05 U2OS 48 3985 Anaphase +0.17086808517092178 3.120381257167376e-64 BR00117023 ABL1 final orf C01 U2OS 48 5005 Anaphase +0.147387008718327 1.6352863355596716e-59 BR00117022 CDC25A final orf M04 U2OS 48 6235 Anaphase +0.16361724500525762 5.948474878382393e-56 BR00117022 LYN final orf C20 U2OS 48 4755 Anaphase +0.14817139929704706 1.9559351855294732e-50 BR00117022 CDC25A final orf I19 U2OS 48 5215 Anaphase +0.1559152887807445 1.2362767059674478e-48 BR00117023 F10 final orf I04 U2OS 48 4540 Anaphase +0.15749029808922585 1.7279905888914583e-47 BR00117023 PLA2G1B final orf E06 U2OS 48 4350 Anaphase +0.13693812802399213 8.38119357374503e-43 BR00117023 PTGIR final orf C07 U2OS 48 5175 Anaphase +0.13669990093631162 1.1699478029059386e-40 BR00117023 PAK1 final orf L12 U2OS 48 4940 Anaphase +0.18455084483451253 2.1187672628205414e-39 BR00117023 HSD11B1 final orf C02 U2OS 48 2615 Anaphase +0.16060778986278734 5.282306445360229e-39 BR00117023 KRAS final orf F08 U2OS 48 3425 Anaphase +0.1273381233521347 2.6380182854040994e-38 BR00117023 SCNN1G final orf O03 U2OS 48 5355 Anaphase +0.12273490971037504 8.133678438693318e-33 BR00117023 GLRA3 final orf K04 U2OS 48 4935 Anaphase +0.11337541807628569 1.01558331892205e-29 BR00117023 CDC25A final orf I19 U2OS 48 5225 Anaphase +0.12170819853470417 3.3669734134283746e-29 BR00117023 LYN final orf C20 U2OS 48 4450 Anaphase +0.10556030795551753 9.221212938167856e-29 BR00117023 HCK final orf O01 U2OS 48 5845 Anaphase +0.12761536630271408 3.497815764340218e-27 BR00117023 PTK2B final orf N19 U2OS 48 3770 Anaphase +0.10893203883495145 5.137686609225339e-27 BR00117022 CYP1A2 final orf F21 U2OS 48 5150 Anaphase +0.10859903381642512 5.5604684614863776e-27 BR00117022 CLK1 final orf D08 U2OS 48 5175 Anaphase +0.11161290322580646 1.24119078368405e-25 BR00117023 ATM final orf C04 U2OS 48 4650 Anaphase +0.13171471927162368 2.549481822775287e-25 BR00117023 PTK2B final orf J18 U2OS 48 3295 Anaphase +0.13095425926201568 3.191681079387745e-24 BR00117022 HSD11B1 final orf C02 U2OS 48 3175 Anaphase +0.09856887298747764 4.760398835031468e-24 BR00117023 CDK2 final orf L03 U2OS 48 5590 Anaphase +0.0989892509887762 3.570472334668097e-23 BR00117023 SIRT2 final orf G02 U2OS 48 5320 Anaphase +0.12007010683351207 1.6577872414717842e-22 BR00117022 KRAS final orf F08 U2OS 48 3515 Anaphase +0.10989137141791151 5.0798949076867064e-21 BR00117022 PTK2B final orf N19 U2OS 48 3915 Anaphase +0.0932362056103422 1.4758974098798407e-20 BR00117023 KDR final orf O02 U2OS 48 5315 Anaphase +0.11657921757563397 2.3918927490324507e-20 BR00117022 PTK2B final orf J18 U2OS 48 3365 Anaphase +0.09646945117853224 3.948227203835609e-20 BR00117022 SIRT2 final orf G02 U2OS 48 4865 Anaphase +0.10201106908205101 5.1684514420167484e-20 BR00117022 PTGIS final orf F16 U2OS 48 4320 Anaphase +0.09700854700854701 1.3990205053113086e-19 BR00117023 PTGIR final orf E16 U2OS 48 4680 Anaphase +0.09335228759664514 6.530495034892276e-19 BR00117023 RET final orf E03 U2OS 48 4860 Anaphase +0.08910447593136558 7.17408854219923e-19 BR00117022 PAK1 final orf L12 U2OS 48 5330 Anaphase +0.09514707454117935 1.7402562140220664e-18 BR00117023 CLK1 final orf D08 U2OS 48 4580 Anaphase +0.0816983665709896 1.769456298610539e-18 BR00117023 KCNQ2 final orf K01 U2OS 48 6215 Anaphase +0.08751553007627762 6.0715954929890395e-18 BR00117023 CCND1 final orf P16 U2OS 48 5240 Anaphase +0.08666020337176773 1.947164072716766e-17 BR00117023 GLRA3 final orf E05 U2OS 48 5200 Anaphase +0.08899907430697945 3.3978240349594454e-17 BR00117023 KCNMA1 final orf G01 U2OS 48 4860 Anaphase +0.08635477582846005 4.655187759999997e-17 BR00117023 PAK1 final orf L09 U2OS 48 5130 Anaphase +0.08668916245592206 6.094881409442773e-16 BR00117022 PRKCE final orf J19 U2OS 48 4745 Anaphase +0.08480985157004775 2.1948674721089054e-15 BR00117023 CSK final orf B04 U2OS 48 4765 Anaphase +0.08330422655232037 2.6030477403420647e-15 BR00117023 FPR1 final orf L04 U2OS 48 4920 Anaphase +0.08220898084267164 2.729183483427731e-15 BR00117022 MET final orf C03 U2OS 48 5050 Anaphase +0.08375987372387965 7.3934824877536e-15 BR00117023 CLK1 final orf J17 U2OS 48 4725 Anaphase +0.0783907044031793 1.1126453558347753e-14 BR00117023 KCNQ2 final orf K02 U2OS 48 5315 Anaphase +0.08109687171344655 1.3217707658224514e-14 BR00117022 ABL1 final orf M24 U2OS 48 4940 Anaphase +0.0811644192275808 1.6247747952547964e-14 BR00117022 GPR55 final orf H16 U2OS 48 4900 Anaphase +0.09428473504826825 1.7444356737746755e-14 BR00117022 ABL1 final orf C01 U2OS 48 3625 Anaphase +0.08005743873919206 4.5998316482853815e-14 BR00117022 MAPK14 final orf G15 U2OS 48 4890 Anaphase +0.09453684522047943 1.3436778905607652e-13 BR00117023 HSD11B1 final orf G23 U2OS 48 3375 Anaphase +0.07556639699874979 1.5142819033237227e-13 BR00117022 CDK2 final orf J04 U2OS 48 5275 Anaphase +0.07383276176407388 2.389339868141381e-13 BR00117023 CACNB4 final orf M01 U2OS 48 5435 Anaphase +0.07720138150624112 7.842858481959698e-13 BR00117023 PRKCE final orf J19 U2OS 48 4780 Anaphase +0.07708722020573325 9.576636210418922e-13 BR00117022 PAK1 final orf L09 U2OS 48 4765 Anaphase +0.0802922133478737 1.0349475743647168e-12 BR00117023 SCNN1G final orf A04 U2OS 48 4370 Anaphase +0.07642782969885774 1.1903062667345446e-12 BR00117022 PTGIR final orf E16 U2OS 48 4815 Anaphase +0.08752305767027872 1.475562685161997e-12 BR00117023 KRAS final orf D17 U2OS 48 3635 Anaphase +0.07223033014793809 2.4016388163648834e-12 BR00117023 CDK2 final orf J04 U2OS 48 5240 Anaphase +0.07502431090380321 6.292003691238097e-12 BR00117022 BRAF final orf C05 U2OS 48 4695 Anaphase +0.07444794952681388 7.0144602360679655e-12 BR00117022 PORCN final orf D22 U2OS 48 4755 Anaphase +0.06978588558522097 7.431054010136294e-12 BR00117022 RET final orf E03 U2OS 48 5385 Anaphase +0.06913047069354633 8.481500037306428e-12 BR00117023 KCNJ1 final orf M03 U2OS 48 5465 Anaphase +0.07106317012327466 9.485537565968517e-12 BR00117023 AKR1C1 final orf I01 U2OS 48 5140 Anaphase +0.07260049860255315 1.0766550777760171e-11 BR00117023 MMP2 final orf F06 U2OS 48 4905 Anaphase +0.07031267749415737 1.6553374149314753e-11 BR00117022 EZH2 final orf D04 U2OS 48 5140 Anaphase +0.07512710885424441 1.663505191776288e-11 BR00117023 SLC7A11 final orf G24 U2OS 48 4505 Anaphase +0.07642824982173133 2.071664558153263e-11 BR00117022 CCR1 final orf F24 U2OS 48 4310 Anaphase +0.06970992445220649 2.3291425035533036e-11 BR00117022 CLK1 final orf J17 U2OS 48 5170 Anaphase +0.07642276422764227 2.355823913176618e-11 BR00117022 HDAC3 final orf N06 U2OS 48 4305 Anaphase +0.07207586933614331 3.868446509292852e-11 BR00117023 GHSR final orf C24 U2OS 48 4745 Anaphase +0.07080555882900469 5.072085778832294e-11 BR00117022 CDK2 final orf L03 U2OS 48 4840 Anaphase +0.0704814918315694 5.532030653331039e-11 BR00117023 PIK3CG final orf I03 U2OS 48 4885 Anaphase +0.06699029126213592 1.8081042449512328e-10 BR00117022 FFAR4 final orf C17 U2OS 48 5150 Anaphase +0.06978265489893397 1.8427669426589173e-10 BR00117022 PTGIS final orf H13 U2OS 48 4730 Anaphase +0.06816508040779982 3.0752534715309206e-10 BR00117023 GUCY1B1 final orf J08 U2OS 48 4835 Anaphase +0.06439170357715081 6.24917311562054e-10 BR00117022 OPRL1 final orf O16 U2OS 48 5270 Anaphase +0.06712080703386458 7.974166154777218e-10 BR00117023 BRAF final orf C05 U2OS 48 4790 Anaphase +0.06940584361088356 8.297677636557302e-10 BR00117023 PORCN final orf D22 U2OS 48 4470 Anaphase +0.06203208556149733 8.330255036380854e-10 BR00117023 EDNRB final orf M08 U2OS 48 5610 Anaphase +0.06902654867256637 8.740504422950808e-10 BR00117022 SCNN1G final orf A04 U2OS 48 4520 Anaphase +0.06402667326205243 1.404442616610365e-09 BR00117022 OPRL1 final orf A23 U2OS 48 5125 Anaphase +0.061989819617826625 2.0444580809416483e-09 BR00117023 ICAM1 final orf I08 U2OS 48 5370 Anaphase +0.06790964010621746 2.296041109382958e-09 BR00117023 CYP2A6 final orf A20 U2OS 48 4440 Anaphase +0.06914225190291541 3.1706229502411836e-09 BR00117022 CYP2A6 final orf A20 U2OS 48 4220 Anaphase +0.06498414416862627 3.2487533580034077e-09 BR00117023 PTGIS final orf H13 U2OS 48 4775 Anaphase +0.06794216249680722 3.957262758214351e-09 BR00117023 GPR55 final orf H16 U2OS 48 4330 Anaphase +0.06387585991244528 5.831964305228699e-09 BR00117023 AKT1 final orf J16 U2OS 48 4800 Anaphase 0.3552334845036329 5.232050569709e-311 BR00117023 DHH final orf G05 U2OS 48 5540 Apoptosis 0.33413549454982827 2.040118434508849e-279 BR00117023 ADH1C final orf O04 U2OS 48 5640 Apoptosis 0.3526678040241432 4.5446156459396394e-275 BR00117023 HRH4 final orf O06 U2OS 48 4975 Apoptosis @@ -1529,6 +15209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.3411931818181818 2.281737801017754e-218 BR00117023 TUBB4B final orf E04 U2OS 48 4225 Apoptosis 0.31456219232913146 6.1946651268839295e-214 BR00117023 TUBB3 final orf G06 U2OS 48 4880 Apoptosis 0.2974264705882353 1.3398824505526836e-212 BR00117023 CDC25A final orf M04 U2OS 48 5440 Apoptosis +0.3149774113874578 1.4894092677660292e-196 BR00117023 GABRB2 final orf C06 U2OS 48 4475 Apoptosis +0.24985739157801917 1.0961211922996433e-125 BR00117023 KCNN4 final orf A06 U2OS 48 4565 Apoptosis +0.28770864946889224 1.5000510754981578e-120 BR00117023 PTK2B final orf J18 U2OS 48 3295 Apoptosis +0.22848485912808725 4.481196952537196e-115 BR00117023 ABL1 final orf C01 U2OS 48 5005 Apoptosis +0.26250751550113494 2.4205826285878035e-102 BR00117022 PTK2B final orf J18 U2OS 48 3365 Apoptosis +0.20695148973574817 4.715705532773003e-71 BR00117023 PTK2B final orf N19 U2OS 48 3770 Apoptosis +0.20212880451160187 2.195208497554388e-70 BR00117022 PTK2B final orf N19 U2OS 48 3915 Apoptosis +0.17497786952378747 3.9869498517929134e-70 BR00117022 CDC25A final orf I19 U2OS 48 5215 Apoptosis +0.19803728174565396 1.1351835150721922e-62 BR00117022 ABL1 final orf C01 U2OS 48 3625 Apoptosis +0.17090238690848447 1.1927806974210852e-61 BR00117023 LYN final orf M05 U2OS 48 4800 Apoptosis +0.15502643188322482 6.926984709952198e-52 BR00117022 GPR55 final orf H16 U2OS 48 4900 Apoptosis +0.16542066601309574 4.62656888946939e-48 BR00117022 LYN final orf M05 U2OS 48 3985 Apoptosis +0.1947315928081317 7.64779130654315e-44 BR00117023 HSD11B1 final orf C02 U2OS 48 2615 Apoptosis +0.13948589801598726 2.1439160839554394e-41 BR00117023 AKR1C1 final orf A24 U2OS 48 4830 Apoptosis +0.12474356173285603 1.6087394790211798e-35 BR00117023 PTGIR final orf C07 U2OS 48 5175 Apoptosis +0.1301787592008412 1.6199064082928582e-35 BR00117022 LYN final orf C20 U2OS 48 4755 Apoptosis +0.14778831658113314 5.9258005846843385e-34 BR00117022 KRAS final orf F08 U2OS 48 3515 Apoptosis +0.1281720430107527 1.0894297640382612e-33 BR00117023 AKT1 final orf F15 U2OS 48 4650 Apoptosis +0.11050888917628021 1.3468024206355139e-33 BR00117022 CDC25A final orf M04 U2OS 48 6235 Apoptosis +0.13281659944701174 1.2612608750613686e-32 BR00117023 ABL1 final orf M24 U2OS 48 4190 Apoptosis +0.13434091001947512 5.140754080742199e-29 BR00117023 KRAS final orf D17 U2OS 48 3635 Apoptosis +0.13651082966382475 2.520891249238374e-28 BR00117023 KRAS final orf F08 U2OS 48 3425 Apoptosis +0.10920664783849099 6.680079432593492e-28 BR00117022 BTK final orf N01 U2OS 48 5280 Apoptosis +0.11761687311085844 8.011988086812987e-28 BR00117023 F10 final orf I04 U2OS 48 4540 Apoptosis +0.1387707207676545 3.872514688424982e-27 BR00117022 HSD11B1 final orf C02 U2OS 48 3175 Apoptosis +0.11178310740354536 1.69129353691792e-26 BR00117022 P2RY12 final orf B24 U2OS 48 4795 Apoptosis +0.11571428571428571 6.693879195087303e-25 BR00117023 LPAR1 final orf B20 U2OS 48 4200 Apoptosis +0.11264790787678838 1.8280456698755385e-24 BR00117023 PLA2G1B final orf E06 U2OS 48 4350 Apoptosis +0.11254114624520682 2.6255403665211163e-24 BR00117023 GPR55 final orf H16 U2OS 48 4330 Apoptosis +0.10888197167035353 3.424168149632718e-23 BR00117023 SIRT2 final orf A07 U2OS 48 4405 Apoptosis +0.10516129032258065 8.491702796402282e-23 BR00117023 ATM final orf C04 U2OS 48 4650 Apoptosis +0.12187300647791917 2.627305042520946e-22 BR00117023 HSD11B1 final orf G23 U2OS 48 3375 Apoptosis +0.10196315312594383 7.5608392383424305e-22 BR00117022 PTGIS final orf H13 U2OS 48 4730 Apoptosis +0.097691635524246 5.400024550436388e-21 BR00117022 ABL1 final orf M24 U2OS 48 4940 Apoptosis +0.10282715726309512 6.2821816338409386e-21 BR00117023 CYP2A6 final orf A20 U2OS 48 4440 Apoptosis +0.09712779287233839 6.6917228193516565e-21 BR00117022 PAK4 final orf G10 U2OS 48 4975 Apoptosis +0.08852181279119017 3.1479266358899436e-19 BR00117022 PTGIR final orf C07 U2OS 48 5505 Apoptosis +0.09091004926983 3.5492321598987754e-19 BR00117022 KCNN1 final orf A01 U2OS 48 5200 Apoptosis +0.09807417364331414 4.199551226997194e-19 BR00117023 CCR1 final orf F24 U2OS 48 4460 Apoptosis +0.08711204742611241 1.0050872385638367e-18 BR00117023 TGFBR1 final orf O14 U2OS 48 5530 Apoptosis +0.0926231685052065 1.6814631574363992e-18 BR00117022 CDK2 final orf L03 U2OS 48 4840 Apoptosis +0.0991450741178911 2.148823127118722e-18 BR00117022 KRAS final orf D17 U2OS 48 4190 Apoptosis +0.09054037788390219 3.872854025656671e-18 BR00117022 IGF1R final orf N16 U2OS 48 4960 Apoptosis +0.0919031425891182 4.3293582853349614e-18 BR00117023 AKT1 final orf J16 U2OS 48 4800 Apoptosis +0.0948834107930863 5.220153164729044e-18 BR00117023 OPRL1 final orf A23 U2OS 48 4475 Apoptosis +0.08389904264577894 5.2398640916359524e-18 BR00117022 HSP90AB1 final orf P01 U2OS 48 5745 Apoptosis +0.09166666666666666 1.585743605303385e-17 BR00117023 PTGIR final orf E16 U2OS 48 4680 Apoptosis +0.08586869555632373 5.265284963671844e-17 BR00117022 CACNA2D3 final orf L02 U2OS 48 5165 Apoptosis +0.09004455974549726 5.3223938435844457e-17 BR00117023 HDAC3 final orf N06 U2OS 48 4695 Apoptosis +0.08585558852621167 1.2598215314812404e-16 BR00117023 HRH4 final orf O05 U2OS 48 5055 Apoptosis +0.08714347302739932 1.294156821511629e-16 BR00117023 PIK3CG final orf I03 U2OS 48 4885 Apoptosis +0.09309941520467836 1.5396887727051375e-16 BR00117023 CA5A final orf B23 U2OS 48 4275 Apoptosis +0.08215467414854272 1.7317409967428004e-16 BR00117022 AGER final orf H18 U2OS 48 5455 Apoptosis +0.09202030525698841 2.295939864906731e-16 BR00117023 CYP2A6 final orf A15 U2OS 48 4310 Apoptosis +0.08740647068784609 3.604910927668406e-16 BR00117022 CSF1R final orf D14 U2OS 48 4735 Apoptosis +0.08246627326032409 3.7289285522320524e-16 BR00117023 KDR final orf O02 U2OS 48 5315 Apoptosis +0.08748124217560363 5.380037944958815e-16 BR00117023 CATSPER4 final orf D24 U2OS 48 4660 Apoptosis +0.07967892250734074 6.582295056291681e-16 BR00117022 CACNB4 final orf M01 U2OS 48 5600 Apoptosis +0.08533915297610475 1.7723216423477687e-15 BR00117022 HSD11B1 final orf G23 U2OS 48 4750 Apoptosis +0.09791088284286507 1.781375331479324e-15 BR00117022 DYRK1B final orf G13 U2OS 48 3600 Apoptosis +0.08327002859689643 2.8984399446511016e-15 BR00117023 OPRM1 final orf A09 U2OS 48 4915 Apoptosis +0.0825301204819277 3.5853275302325174e-15 BR00117022 GHSR final orf C24 U2OS 48 4980 Apoptosis +0.08419506190349865 3.629299959070005e-15 BR00117022 ANXA1 final orf D23 U2OS 48 4780 Apoptosis +0.08669623059866963 3.65054599825819e-15 BR00117023 CACNB4 final orf A18 U2OS 48 4510 Apoptosis +0.08089668615984405 5.085369923258918e-15 BR00117023 PAK1 final orf L09 U2OS 48 5130 Apoptosis +0.08381996186274192 7.791943395941007e-15 BR00117023 DCK final orf D05 U2OS 48 4710 Apoptosis +0.07760102360899558 1.8025545095672092e-14 BR00117023 SCNN1G final orf O03 U2OS 48 5355 Apoptosis +0.07576323592141797 3.0659356167809554e-14 BR00117022 NTRK1 final orf P02 U2OS 48 5530 Apoptosis +0.0785873699184682 5.0617891502628996e-14 BR00117022 MET final orf C03 U2OS 48 5050 Apoptosis +0.08080096603323698 5.0807562503883487e-14 BR00117023 PTGIS final orf H13 U2OS 48 4775 Apoptosis +0.0762189377876179 5.259820740451536e-14 BR00117022 GHSR final orf A17 U2OS 48 5370 Apoptosis +0.07962748648854633 5.4299576532629095e-14 BR00117023 AGER final orf H18 U2OS 48 4915 Apoptosis +0.07742632836500171 6.043983897081537e-14 BR00117023 CHRM3 final orf A11 U2OS 48 5170 Apoptosis +0.0769264030003472 7.00553504395402e-14 BR00117023 CDC25A final orf I19 U2OS 48 5225 Apoptosis +0.07508362275207281 1.4366375989976675e-13 BR00117022 PLD1 final orf L05 U2OS 48 5360 Apoptosis +0.08107899196872996 1.5062212102440328e-13 BR00117023 CLK1 final orf D08 U2OS 48 4580 Apoptosis +0.0817323117644998 2.1216496626908225e-13 BR00117022 AKR1C1 final orf A24 U2OS 48 4455 Apoptosis +0.08371144801091483 2.510520986938303e-13 BR00117022 CYP2A6 final orf A20 U2OS 48 4220 Apoptosis +0.0682804792616438 2.695011898819108e-13 BR00117022 S1PR1 final orf L01 U2OS 48 6335 Apoptosis +0.07346508113807831 2.941891500711772e-13 BR00117023 P3H1 final orf P24 U2OS 48 5455 Apoptosis +0.07427155570981704 3.636752439387493e-13 BR00117022 FLT3 final orf K13 U2OS 48 5295 Apoptosis +0.07304061345892889 6.670826010692479e-13 BR00117023 CHRM3 final orf A10 U2OS 48 5365 Apoptosis +0.07319791445938048 7.167780158416103e-13 BR00117023 S1PR1 final orf L01 U2OS 48 5335 Apoptosis +0.07503298690697711 7.977397595619075e-13 BR00117022 USP1 final orf G11 U2OS 48 5045 Apoptosis +0.0741747572815534 9.666967357333783e-13 BR00117022 CACNG1 final orf A16 U2OS 48 5150 Apoptosis +0.07646274073004784 1.276778344083547e-12 BR00117022 BRD4 final orf F14 U2OS 48 4790 Apoptosis +0.07127272727272728 1.4392227500865013e-12 BR00117022 DDR2 final orf M02 U2OS 48 5500 Apoptosis +0.06631454951006964 2.3954868475148535e-12 BR00117023 KCNQ2 final orf K01 U2OS 48 6215 Apoptosis +0.07348577866267253 3.4458014272957325e-12 BR00117022 VEGFA final orf B09 U2OS 48 5005 Apoptosis +0.07875903227931069 3.818521216701521e-12 BR00117023 PTGIS final orf F16 U2OS 48 4340 Apoptosis 0.5854287556415216 0.0 BR00117023 ADH1C final orf O04 U2OS 48 5640 Binuclear 0.6170955882352941 0.0 BR00117023 CDC25A final orf M04 U2OS 48 5440 Binuclear 0.5582291625025184 0.0 BR00117023 CDK7 final orf K06 U2OS 48 5015 Binuclear @@ -1539,6 +15309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.47016017720385783 0.0 BR00117023 KCNN4 final orf A06 U2OS 48 4565 Binuclear 0.5871432174313581 0.0 BR00117023 SLC7A11 final orf A03 U2OS 48 4780 Binuclear 0.5796208554677269 0.0 BR00117023 TUBB3 final orf G06 U2OS 48 4880 Binuclear +0.595703125 0.0 BR00117023 TUBB3 final orf K05 U2OS 48 5120 Binuclear +0.5585146023847947 0.0 BR00117023 TUBB4B final orf E04 U2OS 48 4225 Binuclear +0.2484145898049214 5.468392302984736e-136 BR00117023 ABL1 final orf C01 U2OS 48 5005 Binuclear +0.2828528072837633 1.7916801321570717e-116 BR00117023 PTK2B final orf J18 U2OS 48 3295 Binuclear +0.3080435445950129 4.0967414246393244e-110 BR00117023 HSD11B1 final orf C02 U2OS 48 2615 Binuclear +0.25533545400689883 8.358204671972081e-97 BR00117022 PTK2B final orf J18 U2OS 48 3365 Binuclear +0.23681522938028515 3.318164801820123e-93 BR00117023 PTK2B final orf N19 U2OS 48 3770 Binuclear +0.20976586929330832 6.258482610934839e-93 BR00117023 LYN final orf M05 U2OS 48 4800 Binuclear +0.1703642444977918 1.805168846243499e-79 BR00117022 CDC25A final orf M04 U2OS 48 6235 Binuclear +0.2136008802998342 1.2524170753615527e-78 BR00117022 PTK2B final orf N19 U2OS 48 3915 Binuclear +0.1690444746259885 1.7530118451180496e-65 BR00117022 CDC25A final orf I19 U2OS 48 5215 Binuclear +0.20493626859969535 6.75527550201318e-59 BR00117022 HSD11B1 final orf C02 U2OS 48 3175 Binuclear +0.16096869693047572 8.367365144260479e-52 BR00117023 F10 final orf I04 U2OS 48 4540 Binuclear +0.17803690093109162 1.2610953227249373e-50 BR00117022 ABL1 final orf C01 U2OS 48 3625 Binuclear +0.15917923154658456 1.4483463811875338e-44 BR00117022 LYN final orf M05 U2OS 48 3985 Binuclear +0.14300736067297581 8.460674141899725e-43 BR00117022 LYN final orf C20 U2OS 48 4755 Binuclear +0.13151674388292262 1.7153222684394292e-39 BR00117023 PTGIR final orf C07 U2OS 48 5175 Binuclear +0.12454164261635119 1.2004113448182266e-37 BR00117022 PTGIR final orf C07 U2OS 48 5505 Binuclear +0.13223466463640304 1.2393345892321986e-33 BR00117023 PLA2G1B final orf E06 U2OS 48 4350 Binuclear +0.1201925234997577 2.6950466577527926e-33 BR00117023 CDC25A final orf I19 U2OS 48 5225 Binuclear +0.11700381897226594 6.320764586646234e-32 BR00117022 CDK2 final orf J04 U2OS 48 5275 Binuclear +0.1276234324355583 3.1393594749725184e-30 BR00117023 ABL1 final orf M24 U2OS 48 4190 Binuclear +0.09896203685143802 5.658107418462657e-27 BR00117023 KCNQ2 final orf K01 U2OS 48 6215 Binuclear +0.11857142857142858 3.9737912336660145e-26 BR00117023 LPAR1 final orf B20 U2OS 48 4200 Binuclear +0.09932749794049114 2.777138388387009e-23 BR00117023 SIRT2 final orf G02 U2OS 48 5320 Binuclear +0.10193548387096774 1.9178616018871266e-21 BR00117023 AKT1 final orf F15 U2OS 48 4650 Binuclear +0.09923285547213695 7.22656688651927e-21 BR00117023 CSK final orf B04 U2OS 48 4765 Binuclear +0.09935483870967741 2.1642077594318078e-20 BR00117023 ATM final orf C04 U2OS 48 4650 Binuclear +0.09607641900920186 2.6406230887552156e-20 BR00117023 GLRA3 final orf K04 U2OS 48 4935 Binuclear +0.08944656824835591 4.125062495103866e-19 BR00117023 SCNN1G final orf O03 U2OS 48 5355 Binuclear +0.09322039899854614 5.282897359465304e-19 BR00117022 GPR55 final orf H16 U2OS 48 4900 Binuclear +0.11050036719169598 2.0041334067252143e-18 BR00117023 HSD11B1 final orf G23 U2OS 48 3375 Binuclear +0.09027932601081039 6.831512440540679e-18 BR00117023 FPR1 final orf L04 U2OS 48 4920 Binuclear +0.09528945147049335 1.3481787053097784e-17 BR00117023 GPR55 final orf H16 U2OS 48 4330 Binuclear +0.08716523776305748 8.430599427343142e-17 BR00117022 ABL1 final orf M24 U2OS 48 4940 Binuclear +0.09093637313638245 3.470165661319995e-16 BR00117023 SCNN1G final orf A04 U2OS 48 4370 Binuclear +0.09999305941143809 3.835654256999645e-16 BR00117022 DYRK1B final orf G13 U2OS 48 3600 Binuclear +0.07852865697177075 4.2879543735030637e-16 BR00117023 HCK final orf O01 U2OS 48 5845 Binuclear +0.08796017789630797 2.098467505109739e-15 BR00117023 LYN final orf C20 U2OS 48 4450 Binuclear +0.08008949547825352 4.296540612810399e-15 BR00117023 CDK2 final orf J04 U2OS 48 5240 Binuclear +0.08278787051006552 5.2920519123289565e-15 BR00117023 PIK3CG final orf I03 U2OS 48 4885 Binuclear +0.08706947286120087 9.553326645139615e-15 BR00117023 PTGIS final orf F16 U2OS 48 4340 Binuclear +0.07741817165003916 1.9525202304899598e-14 BR00117022 FFAR4 final orf I16 U2OS 48 5355 Binuclear +0.07567084078711986 2.4420218027540472e-14 BR00117023 CDK2 final orf L03 U2OS 48 5590 Binuclear +0.07842258550932875 2.7489251793489e-13 BR00117023 BRAF final orf C05 U2OS 48 4790 Binuclear +0.07224199288256228 3.573534048182075e-13 BR00117022 HCK final orf O01 U2OS 48 5620 Binuclear +0.0720110414108335 9.663677314234096e-13 BR00117022 AGER final orf H18 U2OS 48 5455 Binuclear +0.07298521885455589 2.3106510810021456e-12 BR00117023 AKR1C1 final orf I01 U2OS 48 5140 Binuclear +0.07260087180473943 2.321665177631517e-12 BR00117023 GLRA3 final orf E05 U2OS 48 5200 Binuclear +0.07267436551120582 3.1491146302888934e-12 BR00117022 PDE3A final orf O19 U2OS 48 5125 Binuclear +0.0742055597478524 4.137598566923724e-12 BR00117023 RET final orf E03 U2OS 48 4860 Binuclear +0.07383826952881943 5.6981799980534896e-12 BR00117022 LPAR1 final orf B05 U2OS 48 4865 Binuclear +0.07404392513308705 5.7256579590529644e-12 BR00117022 CDK2 final orf L03 U2OS 48 4840 Binuclear +0.07414992965469873 8.554575690976845e-12 BR00117022 HSD11B1 final orf G23 U2OS 48 4750 Binuclear +0.07370145174576118 1.4860103380785143e-11 BR00117023 HDAC3 final orf N06 U2OS 48 4695 Binuclear +0.07052185989878619 1.5439662421365054e-11 BR00117022 OPRL1 final orf A23 U2OS 48 5125 Binuclear +0.06366812593916464 1.5658222556220202e-11 BR00117023 CSK final orf P05 U2OS 48 6295 Binuclear +0.07680221038546653 1.6108166956257434e-11 BR00117022 PTGIS final orf F16 U2OS 48 4320 Binuclear +0.06796475649590802 2.0011373983912913e-11 BR00117023 KCNJ1 final orf M03 U2OS 48 5465 Binuclear +0.0659536541889483 4.968849168693748e-11 BR00117023 EDNRB final orf M08 U2OS 48 5610 Binuclear +0.06269221978310131 1.9890624886355192e-10 BR00117022 CTSG final orf J12 U2OS 48 5845 Binuclear +0.06557059557263849 2.2380035051823972e-10 BR00117023 KCNQ2 final orf K02 U2OS 48 5315 Binuclear +0.06670936600323604 3.1496248559563014e-10 BR00117022 KCNN1 final orf O10 U2OS 48 5045 Binuclear +0.06748699644086108 5.246863840571538e-10 BR00117023 GUCY1B1 final orf J08 U2OS 48 4835 Binuclear +0.06731196361180873 7.24750730183515e-10 BR00117023 P2RY12 final orf B01 U2OS 48 4790 Binuclear +0.07077185915787024 8.8225249139336e-10 BR00117023 PIK3CG final orf G18 U2OS 48 4285 Binuclear +0.06740447538339565 1.0052312905417371e-09 BR00117022 FPR1 final orf L04 U2OS 48 4695 Binuclear +0.06858407079646017 1.1514350316095333e-09 BR00117022 SCNN1G final orf A04 U2OS 48 4520 Binuclear +0.06029802587878312 1.4082146437925497e-09 BR00117023 ICAM1 final orf I15 U2OS 48 5780 Binuclear +0.0633816425120773 1.850221255198488e-09 BR00117022 CLK1 final orf D08 U2OS 48 5175 Binuclear +0.06482810353685141 2.1093260907061487e-09 BR00117023 MMP2 final orf F06 U2OS 48 4905 Binuclear +0.06330839437056177 2.148066563938612e-09 BR00117022 CASP3 final orf N05 U2OS 48 5130 Binuclear +0.06203615604186489 3.259461988764115e-09 BR00117023 PAK4 final orf G10 U2OS 48 5255 Binuclear +0.06040538233166257 5.406186798829571e-09 BR00117022 RET final orf E03 U2OS 48 5385 Binuclear +0.06474358974358975 5.974362104879016e-09 BR00117023 PTGIR final orf E16 U2OS 48 4680 Binuclear +0.06522106198622528 8.878264085843363e-09 BR00117023 NAMPT final orf L06 U2OS 48 4500 Binuclear +0.0608071512985616 1.776828598259535e-08 BR00117023 FFAR4 final orf I16 U2OS 48 5005 Binuclear +0.06544829993084683 1.7830266244429982e-08 BR00117022 CCR1 final orf F24 U2OS 48 4310 Binuclear +0.06009928743489469 2.1681991478081806e-08 BR00117022 SIRT2 final orf A07 U2OS 48 5055 Binuclear +0.059611650485436894 2.2344091462250963e-08 BR00117022 CYP1A2 final orf F21 U2OS 48 5150 Binuclear +0.06818450961418303 2.2897742370011786e-08 BR00117023 DYRK1B final orf G13 U2OS 48 3910 Binuclear +0.06019399721025965 3.13454659252456e-08 BR00117022 GABRB2 final orf C19 U2OS 48 4945 Binuclear +0.06004056795131846 3.792146905351744e-08 BR00117022 TUBB3 final orf K05 U2OS 48 4930 Binuclear +0.06469687993680885 3.9143955637762716e-08 BR00117022 CYP2A6 final orf A20 U2OS 48 4220 Binuclear +0.056481813447502506 4.020152359657845e-08 BR00117022 CACNG1 final orf E23 U2OS 48 5530 Binuclear +0.0597669913890794 4.1810376720640295e-08 BR00117023 PAK1 final orf L12 U2OS 48 4940 Binuclear +0.05617835828424639 4.4352629788999495e-08 BR00117022 TUBB final orf M16 U2OS 48 5560 Binuclear +0.058421628617378644 4.8468256328520024e-08 BR00117023 PDE3A final orf O19 U2OS 48 5125 Binuclear +0.058317025440313114 5.624847328015007e-08 BR00117022 JAK1 final orf H17 U2OS 48 5110 Binuclear +0.059679144385026736 1.1649143505507812e-07 BR00117023 MAPK14 final orf G22 U2OS 48 4675 Binuclear 0.2734446130500759 8.795019578783293e-109 BR00117023 PTK2B final orf J18 U2OS 48 3295 Elongated 0.2359932722065782 1.4170917748194846e-92 BR00117023 PTK2B final orf N19 U2OS 48 3770 Elongated 0.2399605706571881 1.353506201140905e-85 BR00117022 PTK2B final orf J18 U2OS 48 3365 Elongated @@ -1549,6 +15409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.15445552466684873 5.4480194397094397e-42 BR00117022 LYN final orf M05 U2OS 48 3985 Elongated 0.134692201991598 1.7639751562611344e-39 BR00117023 PAK1 final orf L12 U2OS 48 4940 Elongated 0.1388095238095238 1.111260669157291e-35 BR00117023 LPAR1 final orf B20 U2OS 48 4200 Elongated +0.12586707838232228 1.3926291495928196e-33 BR00117023 LYN final orf M05 U2OS 48 4800 Elongated +0.11312888646854281 2.643249860370242e-31 BR00117023 DHH final orf G05 U2OS 48 5540 Elongated +0.12391805005819756 3.241575631323515e-31 BR00117022 HTR2C final orf M06 U2OS 48 4595 Elongated +0.11952558791437873 9.068842558048818e-31 BR00117022 LPAR1 final orf B05 U2OS 48 4865 Elongated +0.13517845674597567 2.2862382612654542e-30 BR00117022 LPAR1 final orf B20 U2OS 48 3755 Elongated +0.14286798743729812 9.503457876684372e-29 BR00117022 HSD11B1 final orf C02 U2OS 48 3175 Elongated +0.11133114939686918 3.036526539602676e-27 BR00117022 S1PR2 final orf B06 U2OS 48 4960 Elongated +0.11060238554084528 9.787655166366829e-27 BR00117022 ABL1 final orf M24 U2OS 48 4940 Elongated +0.11604930788638275 1.6098070240053408e-26 BR00117023 LYN final orf C20 U2OS 48 4450 Elongated +0.11673455719361411 3.584518002293669e-26 BR00117023 GPR55 final orf H16 U2OS 48 4330 Elongated +0.1152911788768983 4.63129141083901e-26 BR00117022 HTR2C final orf G21 U2OS 48 4420 Elongated +0.10576400067522317 7.51098175745062e-26 BR00117022 CDC25A final orf I19 U2OS 48 5215 Elongated +0.13522181708021153 2.635643166672666e-21 BR00117023 HSD11B1 final orf C02 U2OS 48 2615 Elongated +0.09257611481764874 5.589280140735527e-21 BR00117022 PTGIR final orf C07 U2OS 48 5505 Elongated +0.10244388705696893 8.91786547843977e-21 BR00117023 HTR2C final orf M06 U2OS 48 4455 Elongated +0.09266540368675659 2.2659786797691505e-20 BR00117022 PAK1 final orf L12 U2OS 48 5330 Elongated +0.09553588680310934 5.460161286643013e-20 BR00117023 FPR1 final orf L04 U2OS 48 4920 Elongated +0.09332517263000682 2.05396456849025e-19 BR00117023 ABL1 final orf C01 U2OS 48 5005 Elongated +0.0869485294117647 2.6243712578920983e-18 BR00117023 CDC25A final orf M04 U2OS 48 5440 Elongated +0.0787842730215229 2.8277038201460797e-17 BR00117022 CDC25A final orf M04 U2OS 48 6235 Elongated +0.0929127320790369 3.2466793612735927e-17 BR00117023 S1PR2 final orf B19 U2OS 48 4465 Elongated +0.08781255432431667 3.748349153109827e-17 BR00117023 HRH4 final orf O06 U2OS 48 4975 Elongated +0.09239747086144552 4.108640447625353e-16 BR00117023 S1PR2 final orf B06 U2OS 48 4210 Elongated +0.08512197662062555 1.317038060703782e-15 BR00117023 DYRK1B final orf M12 U2OS 48 4810 Elongated +0.0842158836860973 2.0954684209331112e-15 BR00117023 PTPN2 final orf I02 U2OS 48 4840 Elongated +0.08064726000930973 2.3871028899227042e-15 BR00117023 HCK final orf O20 U2OS 48 5275 Elongated +0.08496011660973297 1.5657549711988975e-14 BR00117023 LPAR1 final orf B05 U2OS 48 4485 Elongated +0.08116545265348596 3.466927805372243e-14 BR00117023 GPR55 final orf F13 U2OS 48 4805 Elongated +0.07805716285289376 2.0376551679930358e-13 BR00117022 GPR55 final orf H16 U2OS 48 4900 Elongated +0.06877135411128489 2.1516625338274564e-13 BR00117023 CSK final orf P05 U2OS 48 6295 Elongated +0.07899497093569834 2.2717743043796696e-13 BR00117022 PAK1 final orf L09 U2OS 48 4765 Elongated +0.07487041724722807 3.0756342942580953e-13 BR00117022 HCK final orf O20 U2OS 48 5255 Elongated +0.07170818505338078 5.507523183142963e-13 BR00117022 HCK final orf O01 U2OS 48 5620 Elongated +0.07717614111581862 5.96891605234605e-13 BR00117023 AKR1C1 final orf A24 U2OS 48 4830 Elongated +0.07919999600422553 1.2304349759051013e-12 BR00117023 GABRB2 final orf C06 U2OS 48 4475 Elongated +0.07698924731182796 2.0911138794631727e-12 BR00117023 AKT1 final orf F15 U2OS 48 4650 Elongated +0.08995648504378898 2.4329896469743776e-12 BR00117023 HSD11B1 final orf G23 U2OS 48 3375 Elongated +0.07607913804531212 4.808764981507141e-12 BR00117022 PRKCB final orf K14 U2OS 48 4610 Elongated +0.07106368098393705 5.17576524659349e-12 BR00117022 OPRL1 final orf O16 U2OS 48 5270 Elongated +0.07496232756542531 8.938436248853323e-12 BR00117022 FLT3 final orf E14 U2OS 48 4635 Elongated +0.07301919322857157 1.1918567069914838e-11 BR00117023 HTR2C final orf G21 U2OS 48 4840 Elongated +0.06684073107049608 1.401909262485249e-11 BR00117022 TUBB final orf E19 U2OS 48 5745 Elongated +0.0727753022722535 1.7070725055825386e-11 BR00117023 AKT1 final orf J16 U2OS 48 4800 Elongated +0.06782379174186981 2.579321070455021e-11 BR00117023 CACNB4 final orf M01 U2OS 48 5435 Elongated +0.0704022661322854 3.776908647160805e-11 BR00117022 IGF1R final orf N16 U2OS 48 4960 Elongated +0.07121032793128831 3.831245249596771e-11 BR00117022 CDK2 final orf L03 U2OS 48 4840 Elongated +0.07468094265027476 3.975948080527803e-11 BR00117023 RNASE1 final orf I18 U2OS 48 4405 Elongated +0.07188799155769302 4.628755557090516e-11 BR00117023 CLK1 final orf J17 U2OS 48 4725 Elongated +0.07042794314770298 1.0338133106096906e-10 BR00117022 HSD11B1 final orf G23 U2OS 48 4750 Elongated +0.07025169322759589 1.1518398117895993e-10 BR00117023 CSK final orf B04 U2OS 48 4765 Elongated +0.06765344201262552 1.469968487295124e-10 BR00117023 IL1B final orf G08 U2OS 48 5075 Elongated +0.06832567854136251 1.7877029995057163e-10 BR00117022 IL1B final orf E15 U2OS 48 4940 Elongated +0.06235119769225583 2.7065946307055337e-10 BR00117023 HSP90AB1 final orf P01 U2OS 48 5815 Elongated +0.06473092852409167 4.009200921201248e-10 BR00117023 PRKCB final orf K19 U2OS 48 5320 Elongated +0.06901709401709402 4.1005956941721866e-10 BR00117023 PTGIR final orf E16 U2OS 48 4680 Elongated +0.0728304181987473 5.209281616023339e-10 BR00117023 FGF1 final orf F22 U2OS 48 4145 Elongated +0.06327272727272727 5.405295747392007e-10 BR00117022 DDR2 final orf M02 U2OS 48 5500 Elongated +0.06750561762331186 6.513059779001122e-10 BR00117023 SLC7A11 final orf A03 U2OS 48 4780 Elongated +0.06339815667555782 6.928015522080645e-10 BR00117023 PNLIP final orf L22 U2OS 48 5405 Elongated +0.06882309829908083 7.024209979745037e-10 BR00117023 CLK1 final orf D08 U2OS 48 4580 Elongated +0.06485436893203883 7.725570646843015e-10 BR00117022 FFAR4 final orf C17 U2OS 48 5150 Elongated +0.07171017089399649 7.966283674815826e-10 BR00117022 KRAS final orf D17 U2OS 48 4190 Elongated +0.06701745955539345 7.975446868694949e-10 BR00117023 FLT3 final orf K13 U2OS 48 4810 Elongated +0.06325578106215968 8.834156963612713e-10 BR00117023 ICAM1 final orf I08 U2OS 48 5370 Elongated +0.062165591845914796 1.08183716043349e-09 BR00117022 AVPR1A final orf D07 U2OS 48 5495 Elongated +0.06413255360623782 1.355778602482779e-09 BR00117023 PAK1 final orf L09 U2OS 48 5130 Elongated +0.06685109191187606 1.605587416846895e-09 BR00117022 PRKCB final orf K19 U2OS 48 4670 Elongated +0.06411606915832499 2.8471145683783393e-09 BR00117023 GLRA3 final orf K04 U2OS 48 4935 Elongated +0.061035458617450626 4.887279063429952e-09 BR00117023 KDR final orf O02 U2OS 48 5315 Elongated +0.0632009058137127 5.186407697488109e-09 BR00117023 KCNJ1 final orf E22 U2OS 48 4925 Elongated +0.05992032456576283 5.778434882023186e-09 BR00117023 P3H1 final orf P24 U2OS 48 5455 Elongated +0.061728409215104973 6.195150324828549e-09 BR00117023 CHEK2 final orf H06 U2OS 48 5115 Elongated +0.0603988603988604 9.022376221078306e-09 BR00117023 VEGFA final orf B09 U2OS 48 5265 Elongated +0.06394877857052847 9.637967113718874e-09 BR00117022 AKT1 final orf J16 U2OS 48 4655 Elongated +0.06582112200997557 1.3457662907125665e-08 BR00117022 PRKCE final orf L14 U2OS 48 4335 Elongated +0.06586782605946276 1.572284496792338e-08 BR00117023 PIK3CG final orf G18 U2OS 48 4285 Elongated +0.05567350969802894 1.7880296767786037e-08 BR00117023 FOXM1 final orf P15 U2OS 48 5955 Elongated +0.06044354745923694 2.0596943570651093e-08 BR00117022 RNASE1 final orf G17 U2OS 48 5020 Elongated +0.06042888030699227 3.656297722493734e-08 BR00117023 AKR1B1 final orf L10 U2OS 48 4870 Elongated +0.059459819964021644 4.0037417074904983e-08 BR00117023 AURKB final orf L19 U2OS 48 4995 Elongated +0.058039961941008564 4.068907202125938e-08 BR00117023 PAK4 final orf G10 U2OS 48 5255 Elongated +0.053181198983246185 4.3980565901226094e-08 BR00117023 KCNQ2 final orf K01 U2OS 48 6215 Elongated +0.0598847402777316 7.71482099294071e-08 BR00117023 CACNG1 final orf E23 U2OS 48 4750 Elongated +0.05627952374829198 9.235746131159055e-08 BR00117023 SIRT2 final orf G02 U2OS 48 5320 Elongated +0.060215053763440864 9.442543470695593e-08 BR00117023 ATM final orf C04 U2OS 48 4650 Elongated +0.06776571742456226 1.0844531258097022e-07 BR00117023 KRAS final orf D17 U2OS 48 3635 Elongated +0.05816303875989542 1.1208531968841661e-07 BR00117023 AGER final orf H18 U2OS 48 4915 Elongated +0.060619469026548675 1.213078394997949e-07 BR00117022 SCNN1G final orf A04 U2OS 48 4520 Elongated +0.054770750002184516 1.261436737992261e-07 BR00117022 CSF1R final orf J07 U2OS 48 5505 Elongated +0.05642512077294686 1.3881167546194662e-07 BR00117022 CLK1 final orf D08 U2OS 48 5175 Elongated 0.21325019367368547 4.740257758446695e-100 BR00117023 ABL1 final orf C01 U2OS 48 5005 Grape 0.17328550837082793 3.4615633580201954e-63 BR00117023 SLC7A11 final orf A03 U2OS 48 4780 Grape 0.16971441254301894 3.654376066446607e-61 BR00117023 AKR1C1 final orf A24 U2OS 48 4830 Grape @@ -1559,6 +15509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.13314273756602985 5.009207827540031e-44 BR00117023 ADH1C final orf O04 U2OS 48 5640 Grape 0.1656119985430873 1.6954750852318025e-42 BR00117022 KRAS final orf F08 U2OS 48 3515 Grape 0.15302490100592908 6.05265439411153e-39 BR00117023 PTK2B final orf N19 U2OS 48 3770 Grape +0.15419143548049277 4.3737174989299085e-38 BR00117022 ABL1 final orf C01 U2OS 48 3625 Grape +0.12900948831041772 1.4899010952213412e-36 BR00117023 HRH4 final orf O06 U2OS 48 4975 Grape +0.12066373358938047 1.3787119076390688e-35 BR00117023 DHH final orf G05 U2OS 48 5540 Grape +0.12095588235294118 4.5123141540438973e-35 BR00117023 CDC25A final orf M04 U2OS 48 5440 Grape +0.1472728772189461 8.385182678213924e-35 BR00117023 KRAS final orf D17 U2OS 48 3635 Grape +0.13774285539105377 8.295306993417411e-33 BR00117022 PTK2B final orf N19 U2OS 48 3915 Grape +0.12114205955840836 1.6085906317324405e-32 BR00117023 CDK7 final orf K06 U2OS 48 5015 Grape +0.118359375 1.2045966504324105e-31 BR00117023 TUBB3 final orf K05 U2OS 48 5120 Grape +0.11869665196145819 1.4721467861602494e-30 BR00117022 GPR55 final orf H16 U2OS 48 4900 Grape +0.11813116313791837 1.745415135117275e-27 BR00117023 CYP2A6 final orf A20 U2OS 48 4440 Grape +0.11497246957865342 6.2021106519226426e-27 BR00117022 HTR2C final orf M06 U2OS 48 4595 Grape +0.11440860215053764 6.492674078941214e-27 BR00117023 AKT1 final orf F15 U2OS 48 4650 Grape +0.10635228492540484 1.9301967933893005e-26 BR00117022 BTK final orf N01 U2OS 48 5280 Grape +0.13108960982548187 4.1805950730931183e-26 BR00117023 KRAS final orf F08 U2OS 48 3425 Grape +0.10938601822687558 7.3372731369483e-26 BR00117023 TUBB3 final orf G06 U2OS 48 4880 Grape +0.10302932080189209 1.1524801953630447e-25 BR00117023 P3H1 final orf P24 U2OS 48 5455 Grape +0.10367967206808426 6.888889703848252e-25 BR00117022 CDC25A final orf I19 U2OS 48 5215 Grape +0.10823774765380605 7.228790995952799e-25 BR00117022 P2RY12 final orf B24 U2OS 48 4795 Grape +0.1086021505376344 2.7420732034445085e-24 BR00117023 ATM final orf C04 U2OS 48 4650 Grape +0.11230746786477104 1.8023056002614795e-23 BR00117022 KRAS final orf D17 U2OS 48 4190 Grape +0.0938207136640557 2.0352618709612078e-22 BR00117022 HSP90AB1 final orf P01 U2OS 48 5745 Grape +0.10289083703107736 1.6144739627686105e-21 BR00117023 KCNN4 final orf A06 U2OS 48 4565 Grape +0.08803841627729571 1.7719327276575524e-21 BR00117022 CDC25A final orf M04 U2OS 48 6235 Grape +0.10403117897937737 3.614431065897834e-20 BR00117022 DYRK1B final orf M12 U2OS 48 4190 Grape +0.10049310328552406 8.206872415803625e-20 BR00117023 RNASE1 final orf I18 U2OS 48 4405 Grape +0.0954722931844703 8.334400643434189e-20 BR00117023 FPR1 final orf D21 U2OS 48 4875 Grape +0.130098880505547 9.094997163067868e-20 BR00117023 HSD11B1 final orf C02 U2OS 48 2615 Grape +0.0991209296169301 1.3462128399108514e-19 BR00117023 GABRB2 final orf C06 U2OS 48 4475 Grape +0.10011695906432748 4.596842188298198e-19 BR00117023 CA5A final orf B23 U2OS 48 4275 Grape +0.09367133790330631 7.481653141684927e-19 BR00117023 DYRK1B final orf M12 U2OS 48 4810 Grape +0.095218535663656 4.754191623597827e-18 BR00117023 CCR1 final orf F24 U2OS 48 4460 Grape +0.0917293318659652 6.324365083383075e-18 BR00117022 ANXA1 final orf D23 U2OS 48 4780 Grape +0.09108427141963728 9.02064014756487e-18 BR00117023 LYN final orf M05 U2OS 48 4800 Grape +0.0916754478398314 9.106883459296748e-18 BR00117023 PDPK1 final orf D06 U2OS 48 4745 Grape +0.09356669247276678 9.49925036135578e-18 BR00117023 P2RY12 final orf B24 U2OS 48 4535 Grape +0.07915961490199969 1.079429948973766e-17 BR00117022 S1PR1 final orf L01 U2OS 48 6335 Grape +0.09671208530805687 1.1902243037566436e-17 BR00117022 CYP2A6 final orf A20 U2OS 48 4220 Grape +0.08828888481097157 2.1026440949290256e-17 BR00117022 VEGFA final orf B09 U2OS 48 5005 Grape +0.08609273972805422 3.024998064155446e-17 BR00117022 KCNN1 final orf A01 U2OS 48 5200 Grape +0.08654970760233918 3.914399897940436e-17 BR00117023 PAK1 final orf L09 U2OS 48 5130 Grape +0.085376624204152 5.946065963153392e-17 BR00117022 GRIN2A final orf I24 U2OS 48 5195 Grape +0.08893572181243414 9.58842570888629e-17 BR00117023 GHSR final orf C24 U2OS 48 4745 Grape +0.0828198193794766 1.0314027774926877e-16 BR00117022 AGER final orf H18 U2OS 48 5455 Grape +0.10104263063730026 1.9415221490742489e-16 BR00117022 DYRK1B final orf G13 U2OS 48 3600 Grape +0.08609199894790921 2.3313755811071213e-16 BR00117023 PAK1 final orf L12 U2OS 48 4940 Grape +0.09148231810170404 2.5130484565271024e-16 BR00117022 CACNB4 final orf A18 U2OS 48 4360 Grape +0.08461943335892916 4.988409370577256e-16 BR00117023 UGT1A9 final orf E24 U2OS 48 4995 Grape +0.0829126213592233 8.114012426034514e-16 BR00117022 CACNG1 final orf A16 U2OS 48 5150 Grape +0.08862477929589459 9.169839829308692e-16 BR00117023 OPRL1 final orf A23 U2OS 48 4475 Grape +0.0893369706781566 1.6391005548623482e-15 BR00117023 PTGIS final orf F16 U2OS 48 4340 Grape +0.08573834205243992 2.365837951202346e-15 BR00117023 CATSPER4 final orf D24 U2OS 48 4660 Grape +0.08701695395304136 3.721380512566443e-15 BR00117023 HTR2C final orf M06 U2OS 48 4455 Grape +0.08170128585558853 4.284488621657826e-15 BR00117023 HRH4 final orf O05 U2OS 48 5055 Grape +0.07934600538926517 1.2115032199231797e-14 BR00117023 PTGIR final orf C07 U2OS 48 5175 Grape +0.08492239467849223 1.4455248012261943e-14 BR00117023 CACNB4 final orf A18 U2OS 48 4510 Grape +0.08174713373946875 1.5159639655168912e-14 BR00117023 HTR2C final orf G21 U2OS 48 4840 Grape +0.08072289156626505 1.5630985030087787e-14 BR00117022 GHSR final orf C24 U2OS 48 4980 Grape +0.08447855689269652 1.814241420602215e-14 BR00117023 SLC7A11 final orf G24 U2OS 48 4505 Grape +0.08229461489818689 2.728838158454243e-14 BR00117023 HDAC3 final orf N06 U2OS 48 4695 Grape +0.0772308083406299 3.212294145718315e-14 BR00117023 KDR final orf O02 U2OS 48 5315 Grape +0.07365899035010012 3.7769612182027003e-14 BR00117023 HSP90AB1 final orf P01 U2OS 48 5815 Grape +0.07819337163730451 4.305167437683891e-14 BR00117022 PDE3A final orf O19 U2OS 48 5125 Grape +0.08280013419481902 4.911291695315165e-14 BR00117023 PRKCE final orf L14 U2OS 48 4550 Grape +0.07373029772329247 6.445767274008213e-14 BR00117022 S100B final orf M20 U2OS 48 5710 Grape +0.08052620496281766 7.808948878491664e-14 BR00117023 CACNG1 final orf E23 U2OS 48 4750 Grape +0.08006110589952053 8.038161644830986e-14 BR00117023 AKT1 final orf J16 U2OS 48 4800 Grape +0.07930267624876876 8.531119528849812e-14 BR00117023 PIK3CG final orf I03 U2OS 48 4885 Grape +0.08025495730285237 1.162945477492265e-13 BR00117023 DCK final orf D05 U2OS 48 4710 Grape +0.07660255642519656 1.2302697564909364e-13 BR00117023 CHRM3 final orf A11 U2OS 48 5170 Grape +0.08342011828587205 1.5886566497588199e-13 BR00117023 CYP2A6 final orf A15 U2OS 48 4310 Grape +0.07185121808168314 1.99471431326722e-13 BR00117023 UGT1A9 final orf O09 U2OS 48 5770 Grape +0.08157176223648265 2.340227589925446e-13 BR00117022 AKR1C1 final orf A24 U2OS 48 4455 Grape +0.0787826278883285 3.0781366318649864e-13 BR00117022 CHRM3 final orf A10 U2OS 48 4740 Grape +0.08258148117030421 3.213930542959559e-13 BR00117022 CCR1 final orf F24 U2OS 48 4310 Grape +0.07507605280118078 3.4671090880779696e-13 BR00117022 TUBB4B final orf E04 U2OS 48 5190 Grape +0.0725698924168396 3.974516053728207e-13 BR00117022 NTRK1 final orf P02 U2OS 48 5530 Grape +0.07586604266127325 4.1281105906849736e-13 BR00117023 GAA final orf N04 U2OS 48 5050 Grape +0.07517538368883926 4.854644106874956e-13 BR00117023 CHEK2 final orf H06 U2OS 48 5115 Grape +0.07797693560358485 5.38887386046593e-13 BR00117022 HSD11B1 final orf G23 U2OS 48 4750 Grape +0.0754526768726744 5.96568851223428e-13 BR00117022 MET final orf C03 U2OS 48 5050 Grape +0.07410012948405918 6.060251018021396e-13 BR00117023 CCND1 final orf P16 U2OS 48 5240 Grape +0.07741809646744788 6.512776148580751e-13 BR00117023 PTGIS final orf H13 U2OS 48 4775 Grape +0.07703910520372795 6.839156373387215e-13 BR00117023 AKR1B1 final orf L17 U2OS 48 4810 Grape +0.07986651835372637 6.871022907545698e-13 BR00117022 SLCO2B1 final orf A02 U2OS 48 4495 Grape +0.07439613526570048 7.103132273883337e-13 BR00117022 CLK1 final orf D08 U2OS 48 5175 Grape +0.07746098862377933 8.708308063649525e-13 BR00117022 PTGIS final orf H13 U2OS 48 4730 Grape +0.06694448862156305 1.4259305903659374e-12 BR00117023 KCNQ2 final orf K01 U2OS 48 6215 Grape +0.07940512952246691 1.5943085812874092e-12 BR00117023 SIRT2 final orf A07 U2OS 48 4405 Grape +0.07306016108242108 2.0311172663848586e-12 BR00117022 CACNA2D3 final orf L02 U2OS 48 5165 Grape +0.07398354036608601 2.613931665466272e-12 BR00117022 PAK4 final orf G10 U2OS 48 4975 Grape 0.1835328381756902 5.682829318802939e-82 BR00117023 DHH final orf G05 U2OS 48 5540 Hole 0.18521168325536674 3.623668814310823e-72 BR00117023 SLC7A11 final orf A03 U2OS 48 4780 Hole 0.1498594568303415 1.0919476140156688e-55 BR00117023 ADH1C final orf O04 U2OS 48 5640 Hole @@ -1569,6 +15609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.13786764705882354 1.800842948344777e-45 BR00117023 CDC25A final orf M04 U2OS 48 5440 Hole 0.13456900252528833 4.588806845793421e-41 BR00117023 GRIN2A final orf A05 U2OS 48 5145 Hole 0.15075191835335783 2.3523502095571446e-36 BR00117022 ABL1 final orf C01 U2OS 48 3625 Hole +0.14021244309559938 1.201258209323499e-28 BR00117023 PTK2B final orf J18 U2OS 48 3295 Hole +0.11409552319997851 4.238278069426688e-28 BR00117023 TUBB3 final orf G06 U2OS 48 4880 Hole +0.13531963282859183 2.7898794937418084e-27 BR00117022 PTK2B final orf J18 U2OS 48 3365 Hole +0.10531400966183575 2.139655273651641e-25 BR00117022 CLK1 final orf D08 U2OS 48 5175 Hole +0.11112836870297832 2.3236194827028443e-24 BR00117023 LYN final orf C20 U2OS 48 4450 Hole +0.09836183354503067 1.2888217570784987e-22 BR00117022 OPRL1 final orf O16 U2OS 48 5270 Hole +0.09994472994342327 2.811956968249888e-22 BR00117023 CDK7 final orf K06 U2OS 48 5015 Hole +0.10818784434672994 7.8488938666872015e-22 BR00117022 DYRK1B final orf M12 U2OS 48 4190 Hole +0.10220039577271 6.411000119835075e-21 BR00117023 SLC7A11 final orf G24 U2OS 48 4505 Hole +0.0974547009040369 1.1491211548295072e-20 BR00117022 MAPK14 final orf G15 U2OS 48 4890 Hole +0.0982086406743941 2.4858523583830633e-20 BR00117023 GHSR final orf C24 U2OS 48 4745 Hole +0.10858638861459012 8.196507722599528e-20 BR00117023 PTK2B final orf N19 U2OS 48 3770 Hole +0.09434584644668678 8.5220151161989e-20 BR00117023 UGT1A9 final orf E24 U2OS 48 4995 Hole +0.10582905119906283 1.6238623564137335e-19 BR00117022 PTK2B final orf N19 U2OS 48 3915 Hole +0.11019572459744587 1.7926813051940425e-19 BR00117022 DYRK1B final orf G13 U2OS 48 3600 Hole +0.10504056806412378 2.871384141152491e-19 BR00117023 DYRK1B final orf G13 U2OS 48 3910 Hole +0.08801431127012523 2.9654505537494386e-19 BR00117023 CDK2 final orf L03 U2OS 48 5590 Hole +0.09838252884699143 1.0310708374367348e-18 BR00117023 PTGIS final orf F16 U2OS 48 4340 Hole +0.08793812820380352 3.397938633210397e-18 BR00117022 BTK final orf N01 U2OS 48 5280 Hole +0.09072300516077808 7.4009352944757e-17 BR00117023 CLK1 final orf D08 U2OS 48 4580 Hole +0.07737991631407985 3.527066227868129e-16 BR00117022 LCK final orf H01 U2OS 48 6030 Hole +0.08580187340334942 4.606294263312655e-16 BR00117023 FPR1 final orf D21 U2OS 48 4875 Hole +0.08285831638633154 6.01807273047291e-16 BR00117022 TUBB4B final orf E04 U2OS 48 5190 Hole +0.0976844587389793 6.986786980243328e-16 BR00117023 PDE7A final orf F20 U2OS 48 3720 Hole +0.08152219246826241 2.1098459922088268e-15 BR00117022 CLK1 final orf J17 U2OS 48 5170 Hole +0.07299962692416292 4.158445093701489e-15 BR00117022 S1PR1 final orf L01 U2OS 48 6335 Hole +0.08658243907068275 5.0719832971412385e-15 BR00117023 GABRB2 final orf C06 U2OS 48 4475 Hole +0.08037449213919802 1.691984301186051e-14 BR00117022 CYP3A4 final orf K22 U2OS 48 4995 Hole +0.08394323003423879 3.3996226368435187e-14 BR00117023 OPRL1 final orf A23 U2OS 48 4475 Hole +0.08388866236197919 4.756875996948712e-14 BR00117023 CYP2A6 final orf A20 U2OS 48 4440 Hole +0.07849512911367497 5.045916628722407e-13 BR00117023 RNASE1 final orf G17 U2OS 48 4685 Hole +0.07161347987124936 9.402841485116027e-13 BR00117022 GPR119 final orf N23 U2OS 48 5515 Hole +0.07781150398331649 1.0107461278265019e-12 BR00117023 TNF final orf C18 U2OS 48 4655 Hole +0.08116959064327485 1.1395289536577453e-12 BR00117023 CA5A final orf B23 U2OS 48 4275 Hole +0.0703904358353511 1.6140158556159162e-12 BR00117022 FOXM1 final orf P15 U2OS 48 5605 Hole +0.07659748944562068 1.8647534217416924e-12 BR00117022 FPR1 final orf L04 U2OS 48 4695 Hole +0.07477858401911909 6.387143669768809e-12 BR00117023 DCK final orf D05 U2OS 48 4710 Hole +0.07820608935622927 6.506518674230381e-12 BR00117022 CCR1 final orf F24 U2OS 48 4310 Hole +0.07526881720430108 7.085081236372282e-12 BR00117023 AKT1 final orf F15 U2OS 48 4650 Hole +0.07387609216750768 7.584592533718812e-12 BR00117023 DYRK1B final orf M12 U2OS 48 4810 Hole +0.07272727272727272 8.34674983528986e-12 BR00117023 IMPDH1 final orf L13 U2OS 48 4950 Hole +0.07339919797649606 8.926896125147094e-12 BR00117023 HTR2C final orf G21 U2OS 48 4840 Hole +0.0691588785046729 1.5140039719990854e-11 BR00117023 S100B final orf M20 U2OS 48 5350 Hole +0.06649260226283725 1.8310224809721834e-11 BR00117022 HSP90AB1 final orf P01 U2OS 48 5745 Hole +0.07396963123644251 2.1763075135609662e-11 BR00117023 ANXA1 final orf D23 U2OS 48 4610 Hole +0.07100696099136021 3.472983984465309e-11 BR00117023 CHEK2 final orf F07 U2OS 48 4890 Hole +0.07330415754923414 4.2433118972754454e-11 BR00117023 CYP1A2 final orf F21 U2OS 48 4570 Hole +0.06392729970410496 5.13080205813804e-11 BR00117022 DHH final orf G05 U2OS 48 5940 Hole +0.07003901633905786 5.863612746066931e-11 BR00117023 KCNJ1 final orf E22 U2OS 48 4925 Hole +0.0685666343375239 6.375313024056471e-11 BR00117023 CHEK2 final orf H06 U2OS 48 5115 Hole +0.0649737302977233 6.69563148345821e-11 BR00117022 S100B final orf M20 U2OS 48 5710 Hole +0.0655081511588042 9.191939068793692e-11 BR00117023 TGFBR1 final orf O14 U2OS 48 5530 Hole +0.07228381374722838 1.1462896964923756e-10 BR00117023 CACNB4 final orf A18 U2OS 48 4510 Hole +0.0676352077012927 1.727692464145463e-10 BR00117023 GAA final orf N04 U2OS 48 5050 Hole +0.06883318066942104 2.729096538449e-10 BR00117023 PRKCE final orf J19 U2OS 48 4780 Hole +0.06546574719584765 2.924783319966577e-10 BR00117023 HCK final orf O20 U2OS 48 5275 Hole +0.07099000815968431 3.2004099962943826e-10 BR00117023 CCR1 final orf F24 U2OS 48 4460 Hole +0.06510395546312371 3.49153900403922e-10 BR00117023 OPRL1 final orf O16 U2OS 48 5290 Hole +0.07113578497504036 6.39274830735834e-10 BR00117023 CYP3A4 final orf K22 U2OS 48 4305 Hole +0.06730969801052376 9.423707861044276e-10 BR00117023 CLK1 final orf J17 U2OS 48 4725 Hole +0.06162994551054252 9.5944916225398e-10 BR00117022 LCK final orf B18 U2OS 48 5625 Hole +0.06689363772438686 9.625273145395664e-10 BR00117023 PTGIS final orf H13 U2OS 48 4775 Hole +0.06541137411759373 1.0449558831602484e-09 BR00117022 PAK4 final orf M19 U2OS 48 4970 Hole +0.06653246820929748 1.1182014751849561e-09 BR00117023 KCNN1 final orf A01 U2OS 48 4800 Hole +0.06343779677113011 1.2410658819425913e-09 BR00117023 BRD4 final orf N17 U2OS 48 5265 Hole +0.06620742226645365 1.2939487762270613e-09 BR00117023 AKR1B1 final orf L17 U2OS 48 4810 Hole +0.06322834783292623 1.5409135713675494e-09 BR00117023 CCND1 final orf P16 U2OS 48 5240 Hole +0.0677444892028683 1.585671004477969e-09 BR00117023 PRKCE final orf L14 U2OS 48 4550 Hole +0.06327718590075582 1.6610905135117274e-09 BR00117022 GRIN2A final orf I24 U2OS 48 5195 Hole +0.061825555850614396 1.95410481483239e-09 BR00117023 PNLIP final orf L22 U2OS 48 5405 Hole +0.05952655166107235 2.4645644675810057e-09 BR00117023 UGT1A9 final orf O09 U2OS 48 5770 Hole +0.06494242555219382 3.806534682309332e-09 BR00117023 CACNG1 final orf E23 U2OS 48 4750 Hole +0.06583570589298626 3.869720635020749e-09 BR00117022 PRKCB final orf K14 U2OS 48 4610 Hole +0.062468998797783885 3.873600123905674e-09 BR00117023 DNMT3A final orf F04 U2OS 48 5115 Hole +0.06384020843920249 4.354833366115487e-09 BR00117022 SIRT2 final orf G02 U2OS 48 4865 Hole +0.06479032054029416 4.4456234166957966e-09 BR00117022 CSF1R final orf D14 U2OS 48 4735 Hole +0.06735159817351598 4.640934737679666e-09 BR00117023 HSP90AA1 final orf C14 U2OS 48 4380 Hole +0.062183235867446396 4.802296197681306e-09 BR00117023 ATP5F1D final orf C21 U2OS 48 5130 Hole +0.05735599094456357 4.835048648189459e-09 BR00117022 MET final orf C08 U2OS 48 6010 Hole +0.06071614079258494 5.071839793027441e-09 BR00117022 PLD1 final orf L05 U2OS 48 5360 Hole +0.06502673796791444 5.136891429058122e-09 BR00117023 MAPK14 final orf G22 U2OS 48 4675 Hole +0.0642781875658588 6.050332617711847e-09 BR00117023 PDPK1 final orf D06 U2OS 48 4745 Hole +0.05944891762451634 6.566769370414616e-09 BR00117022 RPL23A final orf I07 U2OS 48 5505 Hole +0.063113904010701 7.67226547414762e-09 BR00117022 SLC7A11 final orf G24 U2OS 48 4845 Hole +0.06475452636194741 9.557525714251668e-09 BR00117023 PDPK1 final orf H15 U2OS 48 4560 Hole +0.06469648753897443 9.708553791915422e-09 BR00117023 KCNN4 final orf A06 U2OS 48 4565 Hole +0.059841096351101394 1.0303937915044725e-08 BR00117023 PRKCB final orf K19 U2OS 48 5320 Hole +0.061979933997138005 1.0973531309493877e-08 BR00117022 CDK4 final orf B21 U2OS 48 4935 Hole +0.07711970786260414 1.1187251970661878e-08 BR00117022 HSD11B1 final orf C02 U2OS 48 3175 Hole +0.06053384574407367 1.3100774429025801e-08 BR00117022 OPRL1 final orf A23 U2OS 48 5125 Hole 0.39657450098818736 0.0 BR00117023 DHH final orf G05 U2OS 48 5540 Interphase 0.35591857113402897 3.234963787458378e-280 BR00117023 HRH4 final orf O06 U2OS 48 4975 Interphase 0.3164153668073041 4.3016923662278594e-250 BR00117023 ADH1C final orf O04 U2OS 48 5640 Interphase @@ -1579,6 +15709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2953210983447026 2.9944024474017386e-193 BR00117023 CDK7 final orf K06 U2OS 48 5015 Interphase 0.31181891025641023 7.317048635967999e-182 BR00117023 TUBB4B final orf E04 U2OS 48 4225 Interphase 0.28262964952007424 2.176907754558568e-181 BR00117023 GRIN2A final orf A05 U2OS 48 5145 Interphase +0.27093873229060267 6.678357796605245e-145 BR00117023 GABRB2 final orf C06 U2OS 48 4475 Interphase +0.2422517554359344 1.8447537268917444e-129 BR00117023 ABL1 final orf C01 U2OS 48 5005 Interphase +0.293722559040276 1.3446260432246172e-128 BR00117022 PTK2B final orf J18 U2OS 48 3365 Interphase +0.2867981790591806 8.834236946452429e-120 BR00117023 PTK2B final orf J18 U2OS 48 3295 Interphase +0.23515863703019196 6.6881893073699e-92 BR00117023 PTK2B final orf N19 U2OS 48 3770 Interphase +0.22945334069574821 4.748402470767331e-84 BR00117022 ABL1 final orf C01 U2OS 48 3625 Interphase +0.21641508720160404 1.0252296758840949e-80 BR00117022 PTK2B final orf N19 U2OS 48 3915 Interphase +0.24552410765703767 1.3534924990736795e-69 BR00117023 HSD11B1 final orf C02 U2OS 48 2615 Interphase +0.1718710944602685 2.0953170037981827e-59 BR00117023 KCNN4 final orf A06 U2OS 48 4565 Interphase +0.1623763948221028 5.875136524825777e-37 BR00117022 HSD11B1 final orf C02 U2OS 48 3175 Interphase +0.1200848986257087 3.3951357239578876e-31 BR00117022 GPR55 final orf H16 U2OS 48 4900 Interphase +0.1376496082423345 3.4696885032719136e-30 BR00117022 DYRK1B final orf G13 U2OS 48 3600 Interphase +0.11656503228990991 4.47502814139954e-29 BR00117023 AKR1C1 final orf A24 U2OS 48 4830 Interphase +0.10930903461863214 2.3759927746090288e-27 BR00117023 CHRM3 final orf A11 U2OS 48 5170 Interphase +0.10886339937434827 3.759404875162961e-25 BR00117022 P2RY12 final orf B24 U2OS 48 4795 Interphase +0.11117053216242588 2.179304912176149e-24 BR00117023 CYP2A6 final orf A20 U2OS 48 4440 Interphase +0.11228070175438597 7.049659044426624e-24 BR00117023 CA5A final orf B23 U2OS 48 4275 Interphase +0.1052663122785074 1.3592631470311952e-23 BR00117023 LYN final orf M05 U2OS 48 4800 Interphase +0.10861938342567896 2.4401936174427268e-23 BR00117023 CCR1 final orf F24 U2OS 48 4460 Interphase +0.09573542210617929 2.5143070252391887e-23 BR00117022 HSP90AB1 final orf P01 U2OS 48 5745 Interphase +0.10067632850241547 3.0537252719074803e-23 BR00117022 CLK1 final orf D08 U2OS 48 5175 Interphase +0.1020957854857515 3.901301378905843e-23 BR00117022 VEGFA final orf B09 U2OS 48 5005 Interphase +0.09886521317155927 1.1799790232344152e-22 BR00117022 CDC25A final orf I19 U2OS 48 5215 Interphase +0.10135805973444349 3.043362969066521e-22 BR00117023 FPR1 final orf D21 U2OS 48 4875 Interphase +0.0978150890093267 4.35885718421008e-22 BR00117022 TUBB4B final orf E04 U2OS 48 5190 Interphase +0.09674069497781375 5.588477244479107e-22 BR00117022 BTK final orf N01 U2OS 48 5280 Interphase +0.10291608746558187 5.856030761102441e-22 BR00117023 CATSPER4 final orf D24 U2OS 48 4660 Interphase +0.10445020155639072 6.872148356300396e-22 BR00117023 SLC7A11 final orf G24 U2OS 48 4505 Interphase +0.10833333333333334 7.151942182268356e-22 BR00117023 LPAR1 final orf B20 U2OS 48 4200 Interphase +0.10279569892473119 8.432401130739067e-22 BR00117023 AKT1 final orf F15 U2OS 48 4650 Interphase +0.10542781907129546 1.5526897816631733e-21 BR00117022 CACNB4 final orf A18 U2OS 48 4360 Interphase +0.10556692517592992 6.278923801629867e-21 BR00117022 CYP2A6 final orf A20 U2OS 48 4220 Interphase +0.10297602882019642 8.69133293064758e-21 BR00117023 SIRT2 final orf A07 U2OS 48 4405 Interphase +0.09658433302955302 1.1730239002453354e-20 BR00117022 PAK4 final orf M19 U2OS 48 4970 Interphase +0.0997467325251168 2.848886638120052e-20 BR00117023 CLK1 final orf D08 U2OS 48 4580 Interphase +0.1038522383534727 3.928292655324679e-20 BR00117022 DYRK1B final orf M12 U2OS 48 4190 Interphase +0.0971507383487133 5.646160533105734e-20 BR00117022 HSD11B1 final orf G23 U2OS 48 4750 Interphase +0.10326369039039056 6.148255108758574e-20 BR00117023 ABL1 final orf M24 U2OS 48 4190 Interphase +0.10000574392579847 6.422299152916873e-20 BR00117023 OPRL1 final orf A23 U2OS 48 4475 Interphase +0.09506963320916809 4.789828969633316e-19 BR00117022 PTGIS final orf H13 U2OS 48 4730 Interphase +0.09420442571127502 9.7263348383067e-19 BR00117023 GHSR final orf C24 U2OS 48 4745 Interphase +0.08959305336673432 1.3760122940294543e-18 BR00117022 GRIN2A final orf I24 U2OS 48 5195 Interphase +0.0927004819424769 4.704328916732016e-18 BR00117023 DCK final orf D05 U2OS 48 4710 Interphase +0.08979027046253937 5.417104841479975e-18 BR00117023 UGT1A9 final orf E24 U2OS 48 4995 Interphase +0.09661223837364191 6.09440570251117e-18 BR00117023 CYP2A6 final orf A15 U2OS 48 4310 Interphase +0.09091924221380426 6.623032811674055e-18 BR00117023 HIF1A final orf C23 U2OS 48 4850 Interphase +0.08992208672086721 2.4673237933199205e-17 BR00117023 AKT1 final orf J16 U2OS 48 4800 Interphase +0.08972099434800426 3.454989958175906e-17 BR00117023 PTGIS final orf H13 U2OS 48 4775 Interphase +0.08795180722891566 3.554678583352527e-17 BR00117022 GHSR final orf C24 U2OS 48 4980 Interphase +0.07848975405673841 3.6808928401796996e-17 BR00117022 CDC25A final orf M04 U2OS 48 6235 Interphase +0.08769687295226383 4.111115770788953e-17 BR00117022 PAK4 final orf G10 U2OS 48 4975 Interphase +0.08481861307861824 7.544886732272986e-17 BR00117023 CCND1 final orf P16 U2OS 48 5240 Interphase +0.09272935915572944 1.1057828583169787e-16 BR00117023 GPR55 final orf H16 U2OS 48 4330 Interphase +0.09024595086236398 1.5292265834320972e-16 BR00117023 P2RY12 final orf B24 U2OS 48 4535 Interphase +0.07615594320773944 2.0992741484066345e-16 BR00117022 S1PR1 final orf L01 U2OS 48 6335 Interphase +0.08446601941747572 2.120293795719175e-16 BR00117022 CACNG1 final orf A16 U2OS 48 5150 Interphase +0.08957871396895788 3.6699584762246184e-16 BR00117023 CACNB4 final orf A18 U2OS 48 4510 Interphase +0.0951461662276667 3.7998748357349626e-16 BR00117022 LYN final orf M05 U2OS 48 3985 Interphase +0.0862855777194062 5.942669509581509e-16 BR00117022 BRD4 final orf F14 U2OS 48 4790 Interphase +0.08559688208216686 1.6026277478201647e-15 BR00117023 CLK1 final orf J17 U2OS 48 4725 Interphase +0.0855614973262032 2.6356163566479165e-15 BR00117023 MAPK14 final orf G22 U2OS 48 4675 Interphase +0.07684225826436912 3.0141086161652144e-15 BR00117023 UGT1A9 final orf O09 U2OS 48 5770 Interphase +0.08811000418549608 3.997274536131144e-15 BR00117023 PTGIS final orf F16 U2OS 48 4340 Interphase +0.07784633481889339 4.97030904935204e-15 BR00117022 NTRK1 final orf P02 U2OS 48 5530 Interphase +0.08451197837134203 6.873612638374416e-15 BR00117023 CACNG1 final orf A16 U2OS 48 4645 Interphase +0.09811975929762257 1.293644366122491e-14 BR00117023 HSD11B1 final orf G23 U2OS 48 3375 Interphase +0.08451497985870927 1.3163459711044409e-14 BR00117023 PRKCE final orf L14 U2OS 48 4550 Interphase +0.08557620662520977 1.7877148082948542e-14 BR00117023 RNASE1 final orf I18 U2OS 48 4405 Interphase +0.08240574670509762 1.8867938558239605e-14 BR00117022 CSF1R final orf D14 U2OS 48 4735 Interphase +0.08493221256152614 1.9072633076185362e-14 BR00117022 AKR1C1 final orf A24 U2OS 48 4455 Interphase +0.07851362062022955 2.7228583201672263e-14 BR00117022 CACNA2D3 final orf L02 U2OS 48 5165 Interphase +0.07605917286300977 3.506069729672299e-14 BR00117023 P3H1 final orf P24 U2OS 48 5455 Interphase +0.07947649529905981 3.647962146214493e-14 BR00117022 P2RY12 final orf B01 U2OS 48 5000 Interphase +0.08433408850441335 4.0949306333765853e-14 BR00117023 HTR3A final orf H24 U2OS 48 4420 Interphase +0.07425569176882663 4.131712200050682e-14 BR00117022 S100B final orf M20 U2OS 48 5710 Interphase +0.08016031039037932 5.60030924691311e-14 BR00117022 SLC7A11 final orf G24 U2OS 48 4845 Interphase +0.08486773649412845 6.094035040173151e-14 BR00117022 CCR1 final orf F24 U2OS 48 4310 Interphase +0.07986482932236187 7.026192805960557e-14 BR00117022 CDK2 final orf L03 U2OS 48 4840 Interphase +0.07750570269426496 9.159599542958571e-14 BR00117022 FGF1 final orf F03 U2OS 48 5090 Interphase +0.08814958463615016 1.0644254450831712e-13 BR00117023 DYRK1B final orf G13 U2OS 48 3910 Interphase +0.08438825176291355 1.9004042205772748e-13 BR00117023 KCNH7 final orf A22 U2OS 48 4190 Interphase +0.07316760296351106 2.4475093202460186e-13 BR00117023 TGFBR1 final orf O14 U2OS 48 5530 Interphase +0.07254747037084236 2.850181313686287e-13 BR00117022 FOXM1 final orf P15 U2OS 48 5605 Interphase +0.0759375642474838 2.883060067949042e-13 BR00117023 CHEK2 final orf H06 U2OS 48 5115 Interphase +0.07628893558754062 2.9248904738819196e-13 BR00117022 SIRT2 final orf A07 U2OS 48 5055 Interphase +0.07636003956478733 3.083270281272383e-13 BR00117023 HRH4 final orf O05 U2OS 48 5055 Interphase +0.0741591930811835 3.127354342809616e-13 BR00117023 S1PR1 final orf L01 U2OS 48 5335 Interphase +0.07759105380835371 3.381110492292732e-13 BR00117022 LPAR1 final orf B05 U2OS 48 4865 Interphase +0.07511276808955764 4.0889517027862906e-13 BR00117022 CLK1 final orf J17 U2OS 48 5170 Interphase +0.07637591299820494 5.681033261743866e-13 BR00117022 CDK4 final orf B21 U2OS 48 4935 Interphase 0.684518288521648 0.0 BR00117023 ADH1C final orf O04 U2OS 48 5640 Large 0.694485294117647 0.0 BR00117023 CDC25A final orf M04 U2OS 48 5440 Large 0.6728875810231384 0.0 BR00117023 CDK7 final orf K06 U2OS 48 5015 Large @@ -1589,6 +15809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5619527446783911 0.0 BR00117023 KCNN4 final orf A06 U2OS 48 4565 Large 0.652220515577849 0.0 BR00117023 SLC7A11 final orf A03 U2OS 48 4780 Large 0.6724300038280469 0.0 BR00117023 TUBB3 final orf G06 U2OS 48 4880 Large +0.6896484375 0.0 BR00117023 TUBB3 final orf K05 U2OS 48 5120 Large +0.6411309844002152 0.0 BR00117023 TUBB4B final orf E04 U2OS 48 4225 Large +0.29398647696690045 2.419895079300189e-191 BR00117023 ABL1 final orf C01 U2OS 48 5005 Large +0.2795392953929539 1.7765551156571736e-165 BR00117023 LYN final orf M05 U2OS 48 4800 Large +0.3001517450682853 2.4665566277203514e-131 BR00117023 PTK2B final orf J18 U2OS 48 3295 Large +0.33439875193820573 4.329134563160314e-130 BR00117023 HSD11B1 final orf C02 U2OS 48 2615 Large +0.23176005598909347 2.6493876531691857e-123 BR00117022 CDC25A final orf I19 U2OS 48 5215 Large +0.27882575426496414 1.3768815929761747e-115 BR00117022 PTK2B final orf J18 U2OS 48 3365 Large +0.20368551082392547 1.2965213634454254e-113 BR00117022 CDC25A final orf M04 U2OS 48 6235 Large +0.243648763102356 2.8277276342617745e-104 BR00117022 LYN final orf M05 U2OS 48 3985 Large +0.23552841210833775 3.6883780016836246e-92 BR00117023 PTK2B final orf N19 U2OS 48 3770 Large +0.20672975814931652 2.6036211089935536e-89 BR00117022 LYN final orf C20 U2OS 48 4755 Large +0.19860782465076673 1.0289207432132483e-78 BR00117023 F10 final orf I04 U2OS 48 4540 Large +0.2175743863775062 2.3269800620012426e-66 BR00117022 HSD11B1 final orf C02 U2OS 48 3175 Large +0.20219349187912947 2.4345380126819517e-65 BR00117022 ABL1 final orf C01 U2OS 48 3625 Large +0.19342919052334007 1.8261955164030963e-64 BR00117022 PTK2B final orf N19 U2OS 48 3915 Large +0.18319586756759615 3.2822676103505e-64 BR00117023 PLA2G1B final orf E06 U2OS 48 4350 Large +0.15547507138068642 4.9164468902961716e-55 BR00117023 PTGIR final orf C07 U2OS 48 5175 Large +0.16338905566402745 2.6393997998235322e-49 BR00117023 ABL1 final orf M24 U2OS 48 4190 Large +0.1441449166229238 8.598015973000452e-48 BR00117023 CDC25A final orf I19 U2OS 48 5225 Large +0.148142584405454 9.707374802473945e-48 BR00117023 GLRA3 final orf K04 U2OS 48 4935 Large +0.13369617778454843 2.2110981643005055e-43 BR00117022 PTGIR final orf C07 U2OS 48 5505 Large +0.14043010752688173 2.22965371710624e-40 BR00117023 ATM final orf C04 U2OS 48 4650 Large +0.13682817784902115 2.6807736433851794e-40 BR00117023 PIK3CG final orf I03 U2OS 48 4885 Large +0.12958744116445972 2.3332808319684892e-39 BR00117023 SIRT2 final orf G02 U2OS 48 5320 Large +0.11516769928973977 2.516371117523522e-36 BR00117023 KCNQ2 final orf K01 U2OS 48 6215 Large +0.15569804785549088 3.706504804571821e-36 BR00117023 HSD11B1 final orf G23 U2OS 48 3375 Large +0.11308810949529513 5.891426905767911e-33 BR00117023 HCK final orf O01 U2OS 48 5845 Large +0.11941747572815534 2.1506008428061943e-32 BR00117022 CYP1A2 final orf F21 U2OS 48 5150 Large +0.12873249034966244 1.045509286300384e-31 BR00117023 GPR55 final orf H16 U2OS 48 4330 Large +0.11387754653849592 1.1179327469302988e-30 BR00117023 SCNN1G final orf O03 U2OS 48 5355 Large +0.11814316851827109 1.590944855051719e-30 BR00117022 ABL1 final orf M24 U2OS 48 4940 Large +0.10983899821109123 9.019208100124338e-30 BR00117023 CDK2 final orf L03 U2OS 48 5590 Large +0.11772524070807719 2.9958474470876187e-29 BR00117023 CSK final orf B04 U2OS 48 4765 Large +0.11023568574845136 3.256399971412041e-28 BR00117023 CDK2 final orf J04 U2OS 48 5240 Large +0.11852833991226408 1.2031214376906604e-27 BR00117023 LYN final orf C20 U2OS 48 4450 Large +0.10910910598164557 6.892027398889979e-26 BR00117022 GPR55 final orf H16 U2OS 48 4900 Large +0.10099667176881601 7.4074267153017e-24 BR00117022 CDK2 final orf J04 U2OS 48 5275 Large +0.1245351719203809 1.2242719161939244e-23 BR00117023 KRAS final orf F08 U2OS 48 3425 Large +0.10019315877503293 3.5105825884035797e-23 BR00117023 GLRA3 final orf E05 U2OS 48 5200 Large +0.10005239220582333 6.93359424250451e-22 BR00117023 FPR1 final orf L04 U2OS 48 4920 Large +0.0951143095980691 2.2901014058908792e-21 BR00117023 KDR final orf O02 U2OS 48 5315 Large +0.10359049701172576 9.967275959959904e-21 BR00117023 PTGIS final orf F16 U2OS 48 4340 Large +0.10523809523809524 1.1605992561799414e-20 BR00117023 LPAR1 final orf B20 U2OS 48 4200 Large +0.09871794871794871 2.908642146992504e-20 BR00117023 PTGIR final orf E16 U2OS 48 4680 Large +0.09700640516214307 4.213877443240382e-20 BR00117023 BRAF final orf C05 U2OS 48 4790 Large +0.0935672514619883 5.877908090415057e-20 BR00117023 PAK1 final orf L09 U2OS 48 5130 Large +0.0941395163345113 9.294587227635718e-19 BR00117022 HSD11B1 final orf G23 U2OS 48 4750 Large +0.09165652469601614 3.449603677536108e-18 BR00117023 KCNMA1 final orf G01 U2OS 48 4860 Large +0.09607017566431647 8.674031992960803e-18 BR00117022 PTGIS final orf F16 U2OS 48 4320 Large +0.08514136038700107 3.017450356389326e-17 BR00117022 PAK1 final orf L12 U2OS 48 5330 Large +0.08604505155815989 5.871478152966221e-17 BR00117022 PDE3A final orf O19 U2OS 48 5125 Large +0.08754299221587873 1.2494956803286003e-16 BR00117023 RET final orf E03 U2OS 48 4860 Large +0.08242263796232957 2.9728700950847575e-16 BR00117022 FFAR4 final orf I16 U2OS 48 5355 Large +0.08570565875713992 3.2344219444990504e-16 BR00117023 PAK1 final orf L12 U2OS 48 4940 Large +0.08003565062388592 4.774312318423948e-16 BR00117023 EDNRB final orf M08 U2OS 48 5610 Large +0.10061367788211242 6.117830756412e-16 BR00117022 KRAS final orf F08 U2OS 48 3515 Large +0.0875268817204301 6.483677529037937e-16 BR00117023 AKT1 final orf F15 U2OS 48 4650 Large +0.0825242718446602 1.1304396352511289e-15 BR00117022 FFAR4 final orf C17 U2OS 48 5150 Large +0.08040087225883386 2.2474475410194417e-15 BR00117023 KCNQ2 final orf K02 U2OS 48 5315 Large +0.08650442477876107 3.935896651001126e-15 BR00117022 SCNN1G final orf A04 U2OS 48 4520 Large +0.08464095153603185 4.593346906621677e-15 BR00117022 FPR1 final orf L04 U2OS 48 4695 Large +0.08423771274030531 6.064645922495159e-15 BR00117023 HDAC3 final orf N06 U2OS 48 4695 Large +0.08616635993387758 1.3833420252027165e-14 BR00117023 SCNN1G final orf A04 U2OS 48 4370 Large +0.07526690391459075 2.8983725421658875e-14 BR00117022 HCK final orf O01 U2OS 48 5620 Large +0.0782608695652174 3.334503029037183e-14 BR00117022 CLK1 final orf D08 U2OS 48 5175 Large +0.07955665697973033 5.518025472243376e-14 BR00117023 AGER final orf H18 U2OS 48 4915 Large +0.07991675338189386 9.131765007957716e-14 BR00117023 GPR55 final orf F13 U2OS 48 4805 Large +0.07851181937177862 1.0078190077047037e-13 BR00117022 GABRB2 final orf C19 U2OS 48 4945 Large +0.09082414431264309 1.7228747778462348e-13 BR00117023 KRAS final orf D17 U2OS 48 3635 Large +0.07430150478035298 3.63527426718215e-13 BR00117022 FLT3 final orf K13 U2OS 48 5295 Large +0.07824155172992382 4.849273148845713e-13 BR00117022 PTGIS final orf H13 U2OS 48 4730 Large +0.07269802221753037 5.565223628818001e-13 BR00117022 AGER final orf H18 U2OS 48 5455 Large +0.07584941232652524 7.849167110949446e-13 BR00117023 MAPK14 final orf G15 U2OS 48 4955 Large +0.07467854357839056 9.4830477428747e-13 BR00117023 MET final orf C03 U2OS 48 5080 Large +0.07114382091383012 2.100166304377204e-12 BR00117023 CACNB4 final orf M01 U2OS 48 5435 Large +0.07338551859099804 2.187030029919807e-12 BR00117022 JAK1 final orf H17 U2OS 48 5110 Large +0.07418459081254287 3.280928426878952e-12 BR00117023 PARP3 final orf J20 U2OS 48 4915 Large +0.07314156893988827 4.5195551266329064e-12 BR00117022 ADA final orf P04 U2OS 48 4995 Large +0.07148235204552592 8.104431770318382e-12 BR00117023 PDE3A final orf O19 U2OS 48 5125 Large +0.07419147571002707 9.976162962240934e-12 BR00117023 DCK final orf D05 U2OS 48 4710 Large +0.0732601259584848 1.0202209180602535e-11 BR00117023 HDAC6 final orf K03 U2OS 48 4825 Large +0.07135610058136231 1.2430955418453637e-11 BR00117022 MET final orf C03 U2OS 48 5050 Large +0.07394284209240541 2.4559533004276035e-11 BR00117023 CLK1 final orf D08 U2OS 48 4580 Large +0.0682261208576998 8.383064626179921e-11 BR00117023 KCNMA1 final orf O08 U2OS 48 5130 Large +0.06654275092936802 8.880743597853578e-11 BR00117023 PDE3A final orf O22 U2OS 48 5380 Large +0.07220213893293852 1.4044128237156892e-10 BR00117023 PORCN final orf D22 U2OS 48 4470 Large +0.06767903768972627 1.719874155190336e-10 BR00117022 KCNN1 final orf O10 U2OS 48 5045 Large +0.06748478909788126 1.9417328871829888e-10 BR00117022 USP1 final orf G11 U2OS 48 5045 Large +0.06419658322729731 1.9479030329697946e-10 BR00117023 PLK1 final orf N08 U2OS 48 5570 Large 0.2720355356600792 6.490173820269036e-181 BR00117023 DHH final orf G05 U2OS 48 5540 Metaphase 0.2705078125 3.6544663307093656e-165 BR00117023 TUBB3 final orf K05 U2OS 48 5120 Metaphase 0.2715844089514819 4.016386776127689e-163 BR00117023 CDK7 final orf K06 U2OS 48 5015 Metaphase @@ -1599,6 +15909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.24856462717356928 5.227589272950089e-140 BR00117023 GRIN2A final orf A05 U2OS 48 5145 Metaphase 0.24455970618472742 7.217511731542915e-126 BR00117023 SLC7A11 final orf A03 U2OS 48 4780 Metaphase 0.24210672214133555 1.6905273310196304e-115 BR00117023 GABRB2 final orf C06 U2OS 48 4475 Metaphase +0.23267673489322238 8.602586398134848e-109 BR00117023 KCNN4 final orf A06 U2OS 48 4565 Metaphase +0.2079044117647059 2.7667447476492205e-103 BR00117023 CDC25A final orf M04 U2OS 48 5440 Metaphase +0.14805350914065324 1.2109484011340682e-47 BR00117023 PAK1 final orf L12 U2OS 48 4940 Metaphase +0.15881100056205813 5.977076672667497e-42 BR00117023 PTK2B final orf N19 U2OS 48 3770 Metaphase +0.16358118361153262 6.95719331743598e-39 BR00117023 PTK2B final orf J18 U2OS 48 3295 Metaphase +0.12735713065042784 3.5918374744912884e-28 BR00117022 PTK2B final orf N19 U2OS 48 3915 Metaphase +0.13271381766268578 2.4355839906503653e-26 BR00117022 PTK2B final orf J18 U2OS 48 3365 Metaphase +0.11301156715367235 1.0422909560869097e-25 BR00117023 F10 final orf I04 U2OS 48 4540 Metaphase +0.12866603071314806 3.3954036624285133e-25 BR00117023 KRAS final orf F08 U2OS 48 3425 Metaphase +0.10240897949327837 1.0783743680968431e-24 BR00117023 KDR final orf O02 U2OS 48 5315 Metaphase +0.1038318886870208 1.2783739381535865e-23 BR00117023 GLRA3 final orf K04 U2OS 48 4935 Metaphase +0.11276037764550981 1.2845087621969896e-23 BR00117023 ABL1 final orf M24 U2OS 48 4190 Metaphase +0.11996963009570004 1.724168483571027e-22 BR00117022 KRAS final orf F08 U2OS 48 3515 Metaphase +0.10452983877864953 2.472466729148953e-22 BR00117022 HTR2C final orf M06 U2OS 48 4595 Metaphase +0.10580110157802743 4.985259252464691e-22 BR00117022 HTR2C final orf G21 U2OS 48 4420 Metaphase +0.09973880136563695 2.392809675363938e-21 BR00117023 AKR1C1 final orf A24 U2OS 48 4830 Metaphase +0.09834352000520422 6.287716410248575e-21 BR00117022 LPAR1 final orf B05 U2OS 48 4865 Metaphase +0.11328928578228832 1.0359586672153064e-20 BR00117022 ABL1 final orf C01 U2OS 48 3625 Metaphase +0.09333008674307414 1.1740005130250638e-20 BR00117022 PAK1 final orf L12 U2OS 48 5330 Metaphase +0.09978494623655915 1.4513496993005867e-20 BR00117023 ATM final orf C04 U2OS 48 4650 Metaphase +0.1019047619047619 2.1306815322123535e-19 BR00117023 LPAR1 final orf B20 U2OS 48 4200 Metaphase +0.10741836104667041 2.5049069541468504e-19 BR00117022 LPAR1 final orf B20 U2OS 48 3755 Metaphase +0.09707865462991941 1.066181658338174e-18 BR00117023 HTR2C final orf M06 U2OS 48 4455 Metaphase +0.09327718571843069 2.498044046509452e-18 BR00117023 CLK1 final orf J17 U2OS 48 4725 Metaphase +0.10552090284681838 4.0807428136594285e-18 BR00117023 KRAS final orf D17 U2OS 48 3635 Metaphase +0.0920035631895919 5.542591807624648e-18 BR00117022 PAK1 final orf L09 U2OS 48 4765 Metaphase +0.08324490138377164 7.637705360180667e-17 BR00117023 CACNB4 final orf M01 U2OS 48 5435 Metaphase +0.0921852194875739 9.919802585737915e-17 BR00117023 RNASE1 final orf I18 U2OS 48 4405 Metaphase +0.08691605225449558 2.1877976192452922e-16 BR00117022 CDK2 final orf L03 U2OS 48 4840 Metaphase +0.08382066276803118 4.275170988284451e-16 BR00117023 PAK1 final orf L09 U2OS 48 5130 Metaphase +0.08839427135928267 1.2676262786907717e-15 BR00117023 S1PR2 final orf B19 U2OS 48 4465 Metaphase +0.07959189224706194 4.2384509149811225e-15 BR00117023 SIRT2 final orf G02 U2OS 48 5320 Metaphase +0.08247686553277926 4.822892226602609e-15 BR00117022 IL1B final orf E15 U2OS 48 4940 Metaphase +0.08187525211778943 6.479976664200554e-15 BR00117022 S1PR2 final orf B06 U2OS 48 4960 Metaphase +0.07244882100580365 1.1989452171303495e-14 BR00117023 KCNQ2 final orf K01 U2OS 48 6215 Metaphase +0.07448056455829793 2.2063503290655633e-14 BR00117023 ICAM1 final orf I15 U2OS 48 5780 Metaphase +0.07885290656665284 1.4532316898146955e-13 BR00117023 HTR2C final orf G21 U2OS 48 4840 Metaphase +0.07778889327246426 3.562558468930202e-13 BR00117023 PTPN2 final orf I02 U2OS 48 4840 Metaphase +0.07364727235919472 4.081013670451055e-13 BR00117023 ICAM1 final orf I08 U2OS 48 5370 Metaphase +0.07913988304272147 6.277004208347741e-13 BR00117023 CLK1 final orf D08 U2OS 48 4580 Metaphase +0.07238726376617062 6.925376320356046e-13 BR00117023 P3H1 final orf P24 U2OS 48 5455 Metaphase +0.09492976893956308 7.037383357357367e-13 BR00117022 HSD11B1 final orf C02 U2OS 48 3175 Metaphase +0.07357035423338085 1.3403644639337523e-12 BR00117022 CLK1 final orf J17 U2OS 48 5170 Metaphase +0.07537408857300772 2.336798143809127e-12 BR00117023 DYRK1B final orf M12 U2OS 48 4810 Metaphase +0.0807341352608772 2.4003820632620966e-12 BR00117022 KRAS final orf D17 U2OS 48 4190 Metaphase +0.07437355166226342 2.603064678371023e-12 BR00117022 ABL1 final orf M24 U2OS 48 4940 Metaphase +0.07330984632205552 3.0083007036657692e-12 BR00117022 MET final orf C03 U2OS 48 5050 Metaphase +0.07354664268763346 4.971635168809199e-12 BR00117023 FPR1 final orf L04 U2OS 48 4920 Metaphase +0.07718739976916919 5.766524397946505e-12 BR00117023 LYN final orf C20 U2OS 48 4450 Metaphase +0.07030061106640403 5.861866282154651e-12 BR00117023 SCNN1G final orf O03 U2OS 48 5355 Metaphase +0.06747685691678662 6.071737218547918e-12 BR00117023 HSP90AB1 final orf P01 U2OS 48 5815 Metaphase +0.07299042885926332 9.943987209046454e-12 BR00117023 RET final orf E03 U2OS 48 4860 Metaphase +0.07033816425120773 1.4915525131669544e-11 BR00117022 CLK1 final orf D08 U2OS 48 5175 Metaphase +0.07971341880094487 1.7621142765211042e-11 BR00117022 LYN final orf M05 U2OS 48 3985 Metaphase +0.07213459516298633 3.527267020711878e-11 BR00117022 LYN final orf C20 U2OS 48 4755 Metaphase +0.07234042553191489 4.083541362864543e-11 BR00117023 CSF1R final orf D14 U2OS 48 4700 Metaphase +0.07483847772525881 4.781833434406565e-11 BR00117023 PLA2G1B final orf E06 U2OS 48 4350 Metaphase +0.06958338891112001 5.624656952458161e-11 BR00117023 AURKB final orf L19 U2OS 48 4995 Metaphase +0.0718303298481657 5.723941342706859e-11 BR00117022 BRAF final orf C05 U2OS 48 4695 Metaphase +0.06983900733186137 9.776527715938859e-11 BR00117023 KCNMA1 final orf G01 U2OS 48 4860 Metaphase +0.07381395098337726 9.823544100093566e-11 BR00117023 GPR55 final orf H16 U2OS 48 4330 Metaphase +0.07247386759581882 2.974119474742543e-10 BR00117022 HDAC3 final orf N06 U2OS 48 4305 Metaphase +0.06729140042936785 3.724790361127701e-10 BR00117022 HDAC6 final orf K03 U2OS 48 4940 Metaphase +0.07212342069824255 5.773551375883888e-10 BR00117023 S1PR2 final orf B06 U2OS 48 4210 Metaphase +0.06277030856578789 8.360361028731141e-10 BR00117023 KCNJ1 final orf M03 U2OS 48 5465 Metaphase +0.06288284609286796 1.3139821168659214e-09 BR00117023 PRKCB final orf K19 U2OS 48 5320 Metaphase +0.06336822074215033 1.3534570401640554e-09 BR00117023 PAK4 final orf G10 U2OS 48 5255 Metaphase +0.06501094702888385 2.259743139069873e-09 BR00117022 SIRT2 final orf G02 U2OS 48 4865 Metaphase +0.061506055818852025 4.162620711016977e-09 BR00117023 HCK final orf O20 U2OS 48 5275 Metaphase +0.06438594434021264 4.239920664719213e-09 BR00117023 AKT1 final orf J16 U2OS 48 4800 Metaphase +0.059827622506577874 5.128879190248647e-09 BR00117022 PTGIR final orf C07 U2OS 48 5505 Metaphase +0.06117662904612313 5.277090529838732e-09 BR00117022 OPRL1 final orf O16 U2OS 48 5270 Metaphase +0.05924534022724371 5.475035109687782e-09 BR00117022 CACNB4 final orf M01 U2OS 48 5600 Metaphase +0.06176266560441541 5.6327560904963e-09 BR00117023 AKR1C1 final orf I01 U2OS 48 5140 Metaphase +0.05940124195243047 1.513541559758312e-08 BR00117022 CDK2 final orf J04 U2OS 48 5275 Metaphase +0.0598500927948158 1.958434467681277e-08 BR00117022 CASP3 final orf N05 U2OS 48 5130 Metaphase +0.05781818181818182 2.0525082110602194e-08 BR00117022 DDR2 final orf M02 U2OS 48 5500 Metaphase +0.058094160680471366 2.06842251735857e-08 BR00117023 BTK final orf P10 U2OS 48 5435 Metaphase +0.061282459763611886 2.3241937674053666e-08 BR00117022 BAX final orf K17 U2OS 48 4850 Metaphase +0.061394380853277836 2.6992627812321133e-08 BR00117023 GPR55 final orf F13 U2OS 48 4805 Metaphase +0.059309837765788735 2.9634514845108986e-08 BR00117023 CHEK2 final orf H06 U2OS 48 5115 Metaphase +0.060718345603424165 3.259804837139578e-08 BR00117023 GUCY1B1 final orf J08 U2OS 48 4835 Metaphase +0.06153846153846154 5.092425567373415e-08 BR00117023 FGF1 final orf F03 U2OS 48 4615 Metaphase +0.05677366237731811 6.823050817610475e-08 BR00117022 ITGB2 final orf B12 U2OS 48 5325 Metaphase +0.053176179520286 9.04424655958928e-08 BR00117023 FOXM1 final orf P15 U2OS 48 5955 Metaphase +0.05664862124598511 1.0689252365831842e-07 BR00117023 GLRA3 final orf E05 U2OS 48 5200 Metaphase +0.05838647617245403 1.1185516539356078e-07 BR00117023 CA14 final orf J14 U2OS 48 4875 Metaphase +0.058521560574948665 1.1328993174162341e-07 BR00117022 CHRM2 final orf B03 U2OS 48 4870 Metaphase +0.05804984139925616 1.2842332503455254e-07 BR00117023 PIK3CG final orf I03 U2OS 48 4885 Metaphase +0.05867507886435331 1.5422060494960422e-07 BR00117022 PORCN final orf D22 U2OS 48 4755 Metaphase 0.2266684862689511 3.527276592393931e-125 BR00117023 DHH final orf G05 U2OS 48 5540 MetaphaseAlignment 0.19726205443953476 4.30983335533456e-85 BR00117023 HRH4 final orf O06 U2OS 48 4975 MetaphaseAlignment 0.18815647645079617 5.15749442089889e-76 BR00117023 TUBB3 final orf G06 U2OS 48 4880 MetaphaseAlignment @@ -1609,6 +16009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.15898437402446913 9.174415321770754e-50 BR00117023 GABRB2 final orf C06 U2OS 48 4475 MetaphaseAlignment 0.15186410518222468 1.666778170347975e-48 BR00117023 SLC7A11 final orf A03 U2OS 48 4780 MetaphaseAlignment 0.14121256259058454 3.4390679649967297e-40 BR00117023 KCNN4 final orf A06 U2OS 48 4565 MetaphaseAlignment +0.14306666890801506 4.0702251757933326e-38 BR00117023 TUBB4B final orf E04 U2OS 48 4225 MetaphaseAlignment +0.12629277125583332 3.401791809591092e-36 BR00117023 GRIN2A final orf A05 U2OS 48 5145 MetaphaseAlignment +0.13685663614504504 3.5228655129253145e-30 BR00117023 KRAS final orf D17 U2OS 48 3635 MetaphaseAlignment +0.13461492492807609 3.393953467158857e-28 BR00117022 KRAS final orf F08 U2OS 48 3515 MetaphaseAlignment +0.11407173364594902 7.4382477730327895e-28 BR00117023 AKR1C1 final orf A24 U2OS 48 4830 MetaphaseAlignment +0.10063925387613586 1.0614096599730766e-23 BR00117022 BTK final orf N01 U2OS 48 5280 MetaphaseAlignment +0.10461156382683066 1.2594132649950203e-21 BR00117023 CYP2A6 final orf A20 U2OS 48 4440 MetaphaseAlignment +0.10106214808695596 4.5234758714895724e-21 BR00117023 CACNG1 final orf A16 U2OS 48 4645 MetaphaseAlignment +0.1022861912968548 1.1278987284541388e-19 BR00117022 CYP2A6 final orf A20 U2OS 48 4220 MetaphaseAlignment +0.09567272478077495 2.3518452441225546e-19 BR00117022 CHRM3 final orf A10 U2OS 48 4740 MetaphaseAlignment +0.09862154829361361 8.31960145591671e-19 BR00117023 PTGIS final orf F16 U2OS 48 4340 MetaphaseAlignment +0.09217935349322211 3.829654086782564e-18 BR00117022 P2RY12 final orf B24 U2OS 48 4795 MetaphaseAlignment +0.09318930946392141 7.813937110749101e-18 BR00117022 HTR2C final orf M06 U2OS 48 4595 MetaphaseAlignment +0.09678978237628592 1.5380074797371353e-17 BR00117022 KRAS final orf D17 U2OS 48 4190 MetaphaseAlignment +0.10156552866581618 9.998070617895306e-17 BR00117022 ABL1 final orf C01 U2OS 48 3625 MetaphaseAlignment +0.0837679583351828 2.421320140763634e-16 BR00117022 KCNN1 final orf A01 U2OS 48 5200 MetaphaseAlignment +0.09051213982169463 3.7850079991185164e-16 BR00117023 SIRT2 final orf A07 U2OS 48 4405 MetaphaseAlignment +0.08598901529134087 1.1640958493977819e-15 BR00117022 PTGIS final orf H13 U2OS 48 4730 MetaphaseAlignment +0.08122193480353816 1.627601189940149e-15 BR00117023 CCND1 final orf P16 U2OS 48 5240 MetaphaseAlignment +0.08009387191333302 1.891309934458857e-15 BR00117022 OPRM1 final orf A09 U2OS 48 5375 MetaphaseAlignment +0.08708403473145968 2.1506615864429243e-15 BR00117023 P2RY12 final orf B24 U2OS 48 4535 MetaphaseAlignment +0.0993795194576225 3.4490011054131107e-15 BR00117023 KRAS final orf F08 U2OS 48 3425 MetaphaseAlignment +0.08699326750516692 4.005210752883407e-15 BR00117023 HTR2C final orf M06 U2OS 48 4455 MetaphaseAlignment +0.09784586534870601 1.8639289463725684e-14 BR00117022 PTK2B final orf J18 U2OS 48 3365 MetaphaseAlignment +0.0782444700040952 6.834655112157839e-14 BR00117022 MET final orf C03 U2OS 48 5050 MetaphaseAlignment +0.07862458767617472 7.570520648475883e-14 BR00117022 PAK4 final orf G10 U2OS 48 4975 MetaphaseAlignment +0.073863539445629 8.336471380982644e-14 BR00117022 LCK final orf B18 U2OS 48 5625 MetaphaseAlignment +0.07925788915474989 1.0755533851505072e-13 BR00117022 CDK2 final orf L03 U2OS 48 4840 MetaphaseAlignment +0.07853096324997424 2.9378538900685627e-13 BR00117023 PTGIS final orf H13 U2OS 48 4775 MetaphaseAlignment +0.07670682730923695 3.665236183431502e-13 BR00117022 GHSR final orf C24 U2OS 48 4980 MetaphaseAlignment +0.07982219745320182 3.837148336640934e-13 BR00117023 CLK1 final orf D08 U2OS 48 4580 MetaphaseAlignment +0.091350531107739 2.2110710890808666e-12 BR00117023 PTK2B final orf J18 U2OS 48 3295 MetaphaseAlignment +0.07926462484593802 2.331291120468545e-12 BR00117022 CACNB4 final orf A18 U2OS 48 4360 MetaphaseAlignment +0.07757384715532879 3.962875055937038e-12 BR00117023 CCR1 final orf F24 U2OS 48 4460 MetaphaseAlignment +0.068059181897302 5.445378435001067e-12 BR00117022 HSP90AB1 final orf P01 U2OS 48 5745 MetaphaseAlignment +0.07213402680536107 8.74399985935884e-12 BR00117022 P2RY12 final orf B01 U2OS 48 5000 MetaphaseAlignment +0.06725043782837128 1.1974335949843904e-11 BR00117022 S100B final orf M20 U2OS 48 5710 MetaphaseAlignment +0.0733093673753269 1.4434455575163604e-11 BR00117022 PAK1 final orf L09 U2OS 48 4765 MetaphaseAlignment +0.07193989539141812 2.2458278684459652e-11 BR00117023 TUBB final orf E19 U2OS 48 4855 MetaphaseAlignment +0.06691002808630155 2.408499201269831e-11 BR00117022 CACNB4 final orf M01 U2OS 48 5600 MetaphaseAlignment +0.07474972191323694 2.4230723940167656e-11 BR00117022 SLCO2B1 final orf A02 U2OS 48 4495 MetaphaseAlignment +0.06834429085774597 3.1329021457552093e-11 BR00117023 KDR final orf O02 U2OS 48 5315 MetaphaseAlignment +0.07247058973192846 3.6338409777034617e-11 BR00117022 HTR3A final orf H24 U2OS 48 4690 MetaphaseAlignment +0.07187723437145876 6.394012240236657e-11 BR00117022 AKT1 final orf J16 U2OS 48 4655 MetaphaseAlignment +0.07019361058995205 9.739347783075232e-11 BR00117023 AKT1 final orf J16 U2OS 48 4800 MetaphaseAlignment +0.07252502780867631 1.0594027469829565e-10 BR00117022 AKT1 final orf F15 U2OS 48 4495 MetaphaseAlignment +0.06956756416014624 1.6578500656627748e-10 BR00117022 ANXA1 final orf D23 U2OS 48 4780 MetaphaseAlignment +0.072971738710414 1.8049687196296756e-10 BR00117022 PRKCE final orf L14 U2OS 48 4335 MetaphaseAlignment +0.06542958142669746 1.920703799407261e-10 BR00117022 PLD1 final orf L05 U2OS 48 5360 MetaphaseAlignment +0.07136150442892028 1.9677390709278252e-10 BR00117023 SLC7A11 final orf G24 U2OS 48 4505 MetaphaseAlignment +0.06395437746909648 2.0742379895558417e-10 BR00117022 FOXM1 final orf P15 U2OS 48 5605 MetaphaseAlignment +0.07006859214755326 2.1555826236897065e-10 BR00117023 CATSPER4 final orf D24 U2OS 48 4660 MetaphaseAlignment +0.07116956424539328 2.932506643942086e-10 BR00117022 AKR1C1 final orf A24 U2OS 48 4455 MetaphaseAlignment +0.06895200454378943 3.329464010331506e-10 BR00117023 CLK1 final orf J17 U2OS 48 4725 MetaphaseAlignment +0.07335816170848743 3.3865191318542264e-10 BR00117023 DDR2 final orf A19 U2OS 48 4165 MetaphaseAlignment +0.05928902760786116 3.8686929817930673e-10 BR00117022 S1PR1 final orf L01 U2OS 48 6335 MetaphaseAlignment +0.06554515070089885 8.916607383193155e-10 BR00117022 PPARD final orf M07 U2OS 48 4985 MetaphaseAlignment +0.06864547707947664 8.986705536333747e-10 BR00117023 PRKCE final orf L14 U2OS 48 4550 MetaphaseAlignment +0.07134237812295072 9.900804204636343e-10 BR00117023 ABL1 final orf M24 U2OS 48 4190 MetaphaseAlignment +0.06774193548387097 1.065721953361346e-09 BR00117023 AKT1 final orf F15 U2OS 48 4650 MetaphaseAlignment +0.06411707762463892 1.2457972416000974e-09 BR00117022 GUCY1B1 final orf J08 U2OS 48 5145 MetaphaseAlignment +0.06587686293360331 1.3581082840053528e-09 BR00117022 BAX final orf K17 U2OS 48 4850 MetaphaseAlignment +0.08944394076096938 1.5350626156458128e-09 BR00117023 HSD11B1 final orf C02 U2OS 48 2615 MetaphaseAlignment +0.06924174439638307 1.988317834432506e-09 BR00117023 CYP2A6 final orf A15 U2OS 48 4310 MetaphaseAlignment +0.06762749445676275 2.173997856088518e-09 BR00117023 CACNB4 final orf A18 U2OS 48 4510 MetaphaseAlignment +0.06544650302272254 2.2027447481332705e-09 BR00117023 KCNN1 final orf A01 U2OS 48 4800 MetaphaseAlignment +0.062266408042372066 2.4015998299695924e-09 BR00117022 CA14 final orf N07 U2OS 48 5290 MetaphaseAlignment +0.06503896577119381 2.4321352198162522e-09 BR00117023 GUCY1B1 final orf J08 U2OS 48 4835 MetaphaseAlignment +0.0629126213592233 2.7766321245842487e-09 BR00117022 CACNG1 final orf A16 U2OS 48 5150 MetaphaseAlignment +0.06142753200033726 2.9276272976829535e-09 BR00117022 GHSR final orf A17 U2OS 48 5370 MetaphaseAlignment +0.06184672801782648 4.055781949596237e-09 BR00117022 CDC25A final orf I19 U2OS 48 5215 MetaphaseAlignment +0.06449255752211606 4.57982819566091e-09 BR00117023 TUBB final orf M16 U2OS 48 4755 MetaphaseAlignment +0.067671611514247 4.626320027704192e-09 BR00117022 PTGIS final orf F16 U2OS 48 4320 MetaphaseAlignment +0.06389013571906295 4.833456885670216e-09 BR00117022 SLC7A11 final orf G24 U2OS 48 4845 MetaphaseAlignment +0.05807309187889799 5.2161973391850984e-09 BR00117022 PLK1 final orf N08 U2OS 48 5845 MetaphaseAlignment +0.059373087270005634 5.991706050911201e-09 BR00117022 CSK final orf P05 U2OS 48 5550 MetaphaseAlignment +0.06318765918206343 6.041454805499932e-09 BR00117023 PIK3CG final orf I03 U2OS 48 4885 MetaphaseAlignment +0.062401763760357803 7.11447489285522e-09 BR00117022 PAK4 final orf M19 U2OS 48 4970 MetaphaseAlignment +0.062029859872448766 8.091172590630423e-09 BR00117023 ABL1 final orf C01 U2OS 48 5005 MetaphaseAlignment +0.06296495303316973 8.11920115737557e-09 BR00117022 SIRT2 final orf G02 U2OS 48 4865 MetaphaseAlignment +0.060483091787439616 1.188739186920608e-08 BR00117022 KCNMA1 final orf O08 U2OS 48 5175 MetaphaseAlignment +0.060776300551583826 1.4593140232938093e-08 BR00117022 SIRT2 final orf A07 U2OS 48 5055 MetaphaseAlignment +0.06982903009053502 1.9276163377484828e-08 BR00117023 PTK2B final orf N19 U2OS 48 3770 MetaphaseAlignment +0.05711743772241993 2.161455770410459e-08 BR00117022 HCK final orf O01 U2OS 48 5620 MetaphaseAlignment +0.059473096566219484 2.2165036674838582e-08 BR00117022 CACNA2D3 final orf L02 U2OS 48 5165 MetaphaseAlignment +0.055967556513830265 2.3252614253406505e-08 BR00117023 HSP90AB1 final orf P01 U2OS 48 5815 MetaphaseAlignment +0.060851926977687626 2.3368907253389502e-08 BR00117022 TUBB3 final orf K05 U2OS 48 4930 MetaphaseAlignment +0.06384163100581011 2.7095740028984756e-08 BR00117023 HTR3A final orf H24 U2OS 48 4420 MetaphaseAlignment +0.06333397866847164 2.742630222732461e-08 BR00117022 CYP2A6 final orf A15 U2OS 48 4505 MetaphaseAlignment +0.06163970696289684 3.429437151654837e-08 BR00117022 FPR1 final orf L04 U2OS 48 4695 MetaphaseAlignment 0.555461765848104 0.0 BR00117023 ADH1C final orf O04 U2OS 48 5640 OutOfFocus 0.5290441176470588 0.0 BR00117023 CDC25A final orf M04 U2OS 48 5440 OutOfFocus 0.5464514097842121 0.0 BR00117023 CDK7 final orf K06 U2OS 48 5015 OutOfFocus @@ -1619,6 +16109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.4364398221244793 0.0 BR00117023 KCNN4 final orf A06 U2OS 48 4565 OutOfFocus 0.5513515572594755 0.0 BR00117023 SLC7A11 final orf A03 U2OS 48 4780 OutOfFocus 0.5345510607719223 0.0 BR00117023 TUBB3 final orf G06 U2OS 48 4880 OutOfFocus +0.55859375 0.0 BR00117023 TUBB3 final orf K05 U2OS 48 5120 OutOfFocus +0.553774710866057 0.0 BR00117023 TUBB4B final orf E04 U2OS 48 4225 OutOfFocus +0.24243954207997356 1.1676561529751359e-129 BR00117023 ABL1 final orf C01 U2OS 48 5005 OutOfFocus +0.28465775256677345 6.64731222125712e-94 BR00117023 HSD11B1 final orf C02 U2OS 48 2615 OutOfFocus +0.24127465857359637 1.5237429778177648e-84 BR00117023 PTK2B final orf J18 U2OS 48 3295 OutOfFocus +0.22298193895956328 1.0249541837272614e-73 BR00117022 PTK2B final orf J18 U2OS 48 3365 OutOfFocus +0.1839000938086304 2.41651781209018e-71 BR00117023 LYN final orf M05 U2OS 48 4800 OutOfFocus +0.15543538103218674 1.9035515577784624e-55 BR00117022 CDC25A final orf I19 U2OS 48 5215 OutOfFocus +0.17377572704965188 4.8080655060792904e-52 BR00117022 PTK2B final orf N19 U2OS 48 3915 OutOfFocus +0.15954647009075648 7.294303775452838e-51 BR00117023 F10 final orf I04 U2OS 48 4540 OutOfFocus +0.1457202158145147 3.5530748658829445e-45 BR00117023 AKR1C1 final orf A24 U2OS 48 4830 OutOfFocus +0.1528587592128499 9.365763038759787e-45 BR00117023 PLA2G1B final orf E06 U2OS 48 4350 OutOfFocus +0.13767350315307492 3.647456720948827e-43 BR00117023 PTGIR final orf C07 U2OS 48 5175 OutOfFocus +0.16031616121348208 9.61681670021052e-43 BR00117023 PTK2B final orf N19 U2OS 48 3770 OutOfFocus +0.12416011958678386 2.6269600332291946e-42 BR00117022 CDC25A final orf M04 U2OS 48 6235 OutOfFocus +0.15312531068739468 3.2310989673038625e-41 BR00117022 LYN final orf M05 U2OS 48 3985 OutOfFocus +0.15201127211104554 5.1350369194701165e-37 BR00117022 ABL1 final orf C01 U2OS 48 3625 OutOfFocus +0.12496150721611389 1.0845922660138622e-33 BR00117023 PIK3CG final orf I03 U2OS 48 4885 OutOfFocus +0.15457084877622812 1.3310247658279565e-33 BR00117022 HSD11B1 final orf C02 U2OS 48 3175 OutOfFocus +0.14675280429950005 1.1429520855864774e-32 BR00117023 KRAS final orf F08 U2OS 48 3425 OutOfFocus +0.11720336360540518 2.505291526862265e-32 BR00117023 SIRT2 final orf G02 U2OS 48 5320 OutOfFocus +0.10653385838611619 3.42036200036773e-31 BR00117023 KCNQ2 final orf K01 U2OS 48 6215 OutOfFocus +0.12322580645161291 3.642828112066332e-31 BR00117023 ATM final orf C04 U2OS 48 4650 OutOfFocus +0.13963997726308658 2.5351542959045155e-30 BR00117022 KRAS final orf F08 U2OS 48 3515 OutOfFocus +0.1192429022082019 7.433459805011803e-30 BR00117022 LYN final orf C20 U2OS 48 4755 OutOfFocus +0.11364522417153997 2.933187366083785e-29 BR00117023 PAK1 final orf L09 U2OS 48 5130 OutOfFocus +0.13464317545922405 3.5034197278422637e-29 BR00117023 KRAS final orf D17 U2OS 48 3635 OutOfFocus +0.1150138928810961 1.092381279867373e-28 BR00117022 GPR55 final orf H16 U2OS 48 4900 OutOfFocus +0.1101722459815231 1.5074436867150833e-28 BR00117023 KDR final orf O02 U2OS 48 5315 OutOfFocus +0.11322573984351379 5.326165212267366e-28 BR00117023 PAK1 final orf L12 U2OS 48 4940 OutOfFocus +0.1122752558631872 1.4009835333569754e-27 BR00117023 GLRA3 final orf K04 U2OS 48 4935 OutOfFocus +0.10271763531877341 6.246358913392887e-25 BR00117022 PAK1 final orf L12 U2OS 48 5330 OutOfFocus +0.10009058306036248 3.018543303839103e-24 BR00117023 P3H1 final orf P24 U2OS 48 5455 OutOfFocus +0.10417543838169198 1.1472902948487885e-22 BR00117023 HDAC3 final orf N06 U2OS 48 4695 OutOfFocus +0.09631085179922812 1.4517296440805195e-21 BR00117023 CDC25A final orf I19 U2OS 48 5225 OutOfFocus +0.11522716560893537 5.363706894613367e-20 BR00117023 HSD11B1 final orf G23 U2OS 48 3375 OutOfFocus +0.09147032591893083 6.185426478564265e-20 BR00117023 SCNN1G final orf O03 U2OS 48 5355 OutOfFocus +0.09371552631218 9.509563255628414e-20 BR00117022 MET final orf C03 U2OS 48 5050 OutOfFocus +0.09317507418397626 1.6445102707568224e-19 BR00117023 HRH4 final orf O05 U2OS 48 5055 OutOfFocus +0.08926475735034067 2.199349928807227e-19 BR00117023 KCNJ1 final orf M03 U2OS 48 5465 OutOfFocus +0.09425174514839374 6.111979729528175e-19 BR00117023 BRAF final orf C05 U2OS 48 4790 OutOfFocus +0.09376344086021506 3.330494051328381e-18 BR00117023 AKT1 final orf F15 U2OS 48 4650 OutOfFocus +0.08847427846015453 6.663950209537585e-18 BR00117023 CHEK2 final orf H06 U2OS 48 5115 OutOfFocus +0.08648112106291232 8.994454538820459e-18 BR00117023 KCNQ2 final orf K02 U2OS 48 5315 OutOfFocus +0.085797914843423 7.012404593688217e-17 BR00117022 PDE3A final orf O19 U2OS 48 5125 OutOfFocus +0.09180927668573947 8.574641665563693e-17 BR00117023 CCR1 final orf F24 U2OS 48 4460 OutOfFocus +0.08862333272713903 1.0315521296955716e-16 BR00117022 PAK1 final orf L09 U2OS 48 4765 OutOfFocus +0.08752021710653284 1.3337517625727755e-16 BR00117023 HTR2C final orf G21 U2OS 48 4840 OutOfFocus +0.08325548054900204 2.178766353994353e-16 BR00117022 BTK final orf N01 U2OS 48 5280 OutOfFocus +0.092057787443076 6.245698021056586e-16 BR00117023 ABL1 final orf M24 U2OS 48 4190 OutOfFocus +0.08264592103766072 7.897385462649194e-16 BR00117023 CHRM3 final orf A11 U2OS 48 5170 OutOfFocus +0.0802603539681204 1.0048985756958921e-15 BR00117022 AGER final orf H18 U2OS 48 5455 OutOfFocus +0.08606250833576648 1.224859209378016e-15 BR00117023 DCK final orf D05 U2OS 48 4710 OutOfFocus +0.07953363079060291 1.3316623465319775e-15 BR00117022 PTGIR final orf C07 U2OS 48 5505 OutOfFocus +0.08979856072469813 3.585668513370381e-15 BR00117022 KRAS final orf D17 U2OS 48 4190 OutOfFocus +0.08097087378640777 4.192786328531721e-15 BR00117022 CYP1A2 final orf F21 U2OS 48 5150 OutOfFocus +0.0802665369073874 5.2297718843513365e-15 BR00117023 GLRA3 final orf E05 U2OS 48 5200 OutOfFocus +0.08178747680474145 1.4222507301879478e-14 BR00117023 RET final orf E03 U2OS 48 4860 OutOfFocus +0.08567008684694248 1.6129435856141426e-14 BR00117023 RNASE1 final orf I18 U2OS 48 4405 OutOfFocus +0.0869229734689179 3.065553686821401e-14 BR00117022 DYRK1B final orf M12 U2OS 48 4190 OutOfFocus +0.08177028451001053 3.223188396324717e-14 BR00117023 PDPK1 final orf D06 U2OS 48 4745 OutOfFocus +0.07345517841601393 6.7262781047985e-14 BR00117022 HSP90AB1 final orf P01 U2OS 48 5745 OutOfFocus +0.07612689408673734 1.4977656767210877e-13 BR00117022 GRIN2A final orf I24 U2OS 48 5195 OutOfFocus +0.07363381767589433 1.7515056158733147e-13 BR00117023 TGFBR1 final orf O14 U2OS 48 5530 OutOfFocus +0.07196896414788868 1.798284595117116e-13 BR00117023 ICAM1 final orf I15 U2OS 48 5780 OutOfFocus +0.07516948992587652 2.0490138962393954e-13 BR00117022 CDK2 final orf J04 U2OS 48 5275 OutOfFocus +0.07767346188129803 2.3615955290055847e-13 BR00117023 AGER final orf H18 U2OS 48 4915 OutOfFocus +0.07629977846094696 2.490112123377549e-13 BR00117023 MET final orf C03 U2OS 48 5080 OutOfFocus +0.07100085543199315 3.1240140057363275e-13 BR00117023 HCK final orf O01 U2OS 48 5845 OutOfFocus +0.0796544962327353 4.0311880813536966e-13 BR00117022 HTR2C final orf M06 U2OS 48 4595 OutOfFocus +0.07908040831028045 4.0693695998859504e-13 BR00117023 CATSPER4 final orf D24 U2OS 48 4660 OutOfFocus +0.07697670229871874 8.480300035032291e-13 BR00117022 BRD4 final orf F14 U2OS 48 4790 OutOfFocus +0.07712769610829853 1.0162718814494391e-12 BR00117022 HSD11B1 final orf G23 U2OS 48 4750 OutOfFocus +0.0876025664754149 1.7551371759399255e-12 BR00117022 DYRK1B final orf G13 U2OS 48 3600 OutOfFocus +0.07298343775022453 1.8303208852843603e-12 BR00117023 PLK1 final orf L11 U2OS 48 5185 OutOfFocus +0.07805154410131082 2.3309828385186223e-12 BR00117023 NAMPT final orf L06 U2OS 48 4500 OutOfFocus +0.07817048141922758 2.6362203786120845e-12 BR00117022 AKR1C1 final orf A24 U2OS 48 4455 OutOfFocus +0.0747494244173211 2.6619264773347626e-12 BR00117023 FPR1 final orf D21 U2OS 48 4875 OutOfFocus +0.07523544867232076 3.080960987464283e-12 BR00117022 ANXA1 final orf D23 U2OS 48 4780 OutOfFocus +0.07336898225764162 4.7479361069301634e-12 BR00117023 MAPK14 final orf G15 U2OS 48 4955 OutOfFocus +0.06951199956787298 7.451646421341004e-12 BR00117023 CACNB4 final orf M01 U2OS 48 5435 OutOfFocus +0.07091877875922885 7.73893216904388e-12 BR00117022 KCNN1 final orf A01 U2OS 48 5200 OutOfFocus +0.0671288384046855 8.000028814542215e-12 BR00117023 HSP90AB1 final orf P01 U2OS 48 5815 OutOfFocus +0.07462039045553145 1.392478516850495e-11 BR00117023 ERBB2 final orf E21 U2OS 48 4610 OutOfFocus +0.07695906432748538 1.9738150407426763e-11 BR00117023 CA5A final orf B23 U2OS 48 4275 OutOfFocus +0.07137605097984889 2.0800115875220025e-11 BR00117022 ABL1 final orf M24 U2OS 48 4940 OutOfFocus +0.0663714759535655 3.19563072224514e-11 BR00117022 F10 final orf C09 U2OS 48 5625 OutOfFocus +0.07526132404181185 5.036350185254231e-11 BR00117022 HDAC3 final orf N06 U2OS 48 4305 OutOfFocus +0.07096371750289855 5.791454632616539e-11 BR00117023 AKR1B1 final orf L17 U2OS 48 4810 OutOfFocus +0.07175440417258998 1.2053797243434925e-10 BR00117023 PRKCE final orf L14 U2OS 48 4550 OutOfFocus 0.36743925937410027 0.0 BR00117023 DHH final orf G05 U2OS 48 5540 Polylobed 0.303515625 1.637746075858976e-208 BR00117023 TUBB3 final orf K05 U2OS 48 5120 Polylobed 0.2918775292391159 2.403652259207627e-187 BR00117023 HRH4 final orf O06 U2OS 48 4975 Polylobed @@ -1629,6 +16209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2707416906621248 1.1638649310196481e-144 BR00117023 GABRB2 final orf C06 U2OS 48 4475 Polylobed 0.24130841655026977 6.669862175081464e-132 BR00117023 GRIN2A final orf A05 U2OS 48 5145 Polylobed 0.239360668054945 1.6491313881309664e-120 BR00117023 SLC7A11 final orf A03 U2OS 48 4780 Polylobed +0.23447295333526197 1.7198168821048236e-110 BR00117023 KCNN4 final orf A06 U2OS 48 4565 Polylobed +0.21292641653218577 2.4314890709268775e-84 BR00117023 TUBB4B final orf E04 U2OS 48 4225 Polylobed +0.1527142205860173 1.41874475418307e-49 BR00117023 AKR1C1 final orf A24 U2OS 48 4830 Polylobed +0.16245701555627487 3.024133087030215e-42 BR00117022 ABL1 final orf C01 U2OS 48 3625 Polylobed +0.14267797407855953 6.345912110008127e-40 BR00117023 CYP2A6 final orf A20 U2OS 48 4440 Polylobed +0.13996235178138539 1.5254140260780889e-37 BR00117023 PTGIS final orf F16 U2OS 48 4340 Polylobed +0.15781487101669195 3.2903932067179304e-36 BR00117023 PTK2B final orf J18 U2OS 48 3295 Polylobed +0.12387904066736184 1.840584448843052e-32 BR00117022 P2RY12 final orf B24 U2OS 48 4795 Polylobed +0.12412301126820778 3.3147757187508387e-31 BR00117023 CLK1 final orf D08 U2OS 48 4580 Polylobed +0.12583147829625968 7.750084035486299e-31 BR00117023 SIRT2 final orf A07 U2OS 48 4405 Polylobed +0.14305673640521993 1.852786575672625e-30 BR00117022 PTK2B final orf J18 U2OS 48 3365 Polylobed +0.11334073831705958 5.947216261475826e-30 BR00117022 BTK final orf N01 U2OS 48 5280 Polylobed +0.12243615629561391 6.454656766485562e-29 BR00117022 CACNB4 final orf A18 U2OS 48 4360 Polylobed +0.1230387753211529 6.55162405765097e-29 BR00117022 CCR1 final orf F24 U2OS 48 4310 Polylobed +0.1218460523481258 9.015363300797952e-28 BR00117022 CYP2A6 final orf A20 U2OS 48 4220 Polylobed +0.11480251015134736 1.3294487888326328e-27 BR00117022 PTGIS final orf H13 U2OS 48 4730 Polylobed +0.12168729787869656 1.0846663965535432e-25 BR00117022 PTK2B final orf N19 U2OS 48 3915 Polylobed +0.1047806509991384 2.432124152422405e-24 BR00117023 UGT1A9 final orf E24 U2OS 48 4995 Polylobed +0.09260043827065269 4.067637769312389e-24 BR00117022 S1PR1 final orf L01 U2OS 48 6335 Polylobed +0.09712793733681462 5.349490553071719e-24 BR00117022 HSP90AB1 final orf P01 U2OS 48 5745 Polylobed +0.10213592233009709 8.526170111397831e-24 BR00117022 CACNG1 final orf A16 U2OS 48 5150 Polylobed +0.10441569786804528 2.1398572302884804e-23 BR00117022 CDK2 final orf L03 U2OS 48 4840 Polylobed +0.11793500692359812 2.6887050396203126e-23 BR00117023 PTK2B final orf N19 U2OS 48 3770 Polylobed +0.10802023521220713 4.026624823330478e-23 BR00117023 CCR1 final orf F24 U2OS 48 4460 Polylobed +0.12025444923554623 1.3539564197201577e-22 BR00117022 KRAS final orf F08 U2OS 48 3515 Polylobed +0.10132888427875743 2.496366572747666e-22 BR00117022 GPR55 final orf H16 U2OS 48 4900 Polylobed +0.11675919999152598 4.980141208817264e-22 BR00117023 KRAS final orf D17 U2OS 48 3635 Polylobed +0.09875741517771082 1.1278009536837519e-21 BR00117023 ABL1 final orf C01 U2OS 48 5005 Polylobed +0.10723501400751778 1.8652698727717735e-21 BR00117022 KRAS final orf D17 U2OS 48 4190 Polylobed +0.10510964009400786 3.2101667775344238e-21 BR00117022 PTGIS final orf F16 U2OS 48 4320 Polylobed +0.09438979452779274 3.800865700828152e-21 BR00117023 S1PR1 final orf L01 U2OS 48 5335 Polylobed +0.09451917572982255 8.426180680587376e-21 BR00117023 CCND1 final orf P16 U2OS 48 5240 Polylobed +0.09680920366895977 4.9645465928479935e-20 BR00117023 KCNN1 final orf A01 U2OS 48 4800 Polylobed +0.1030952380952381 7.618181865239294e-20 BR00117023 LPAR1 final orf B20 U2OS 48 4200 Polylobed +0.0978494623655914 8.643735398200338e-20 BR00117023 AKT1 final orf F15 U2OS 48 4650 Polylobed +0.09241386837142682 3.2482429348096116e-19 BR00117023 HTR3A final orf J23 U2OS 48 5045 Polylobed +0.09735279941461904 6.064910261672565e-19 BR00117023 OPRL1 final orf A23 U2OS 48 4475 Polylobed +0.092414049350631 6.343584493459903e-19 BR00117022 PAK4 final orf G10 U2OS 48 4975 Polylobed +0.09169093401924014 1.2849292301013378e-18 BR00117022 PAK4 final orf M19 U2OS 48 4970 Polylobed +0.09136546184738956 1.6728917429321733e-18 BR00117022 GHSR final orf C24 U2OS 48 4980 Polylobed +0.08649701797588734 1.8146944287492973e-18 BR00117022 NTRK1 final orf P02 U2OS 48 5530 Polylobed +0.09445676274944567 6.331446819308949e-18 BR00117023 CACNB4 final orf A18 U2OS 48 4510 Polylobed +0.09364549000749316 1.8113358204634996e-17 BR00117022 AKR1C1 final orf A24 U2OS 48 4455 Polylobed +0.08969075102071229 3.663096222798423e-17 BR00117023 PTGIS final orf H13 U2OS 48 4775 Polylobed +0.09380116959064327 8.774843780531067e-17 BR00117023 CA5A final orf B23 U2OS 48 4275 Polylobed +0.08494282626009785 1.0918362031065656e-16 BR00117023 CHRM3 final orf A11 U2OS 48 5170 Polylobed +0.0815979036574487 1.1290410227440602e-16 BR00117022 FOXM1 final orf P15 U2OS 48 5605 Polylobed +0.08872497365648051 1.1457769573962874e-16 BR00117023 GHSR final orf C24 U2OS 48 4745 Polylobed +0.09269117312265983 1.3728374617406795e-16 BR00117023 CYP2A6 final orf A15 U2OS 48 4310 Polylobed +0.08882811391760749 2.0196553113997276e-16 BR00117023 CACNG1 final orf A16 U2OS 48 4645 Polylobed +0.08699516828243076 4.913681923602149e-16 BR00117022 CHRM3 final orf A10 U2OS 48 4740 Polylobed +0.08085630917403985 5.795263083205446e-16 BR00117023 P3H1 final orf P24 U2OS 48 5455 Polylobed +0.08755505551216107 8.543959407418394e-16 BR00117022 HTR2C final orf M06 U2OS 48 4595 Polylobed +0.08487904879048791 9.632440031384911e-16 BR00117023 FPR1 final orf D21 U2OS 48 4875 Polylobed +0.083793277070588 1.0024853894385392e-15 BR00117023 CDK4 final orf B21 U2OS 48 4995 Polylobed +0.0820473981682868 1.0545176079619227e-15 BR00117022 KCNN1 final orf A01 U2OS 48 5200 Polylobed +0.08508721472341074 1.5685419467766618e-15 BR00117022 ANXA1 final orf D23 U2OS 48 4780 Polylobed +0.08181592451580864 1.62064135982269e-15 BR00117023 DDR2 final orf M02 U2OS 48 5180 Polylobed +0.08313062612522505 1.6526269613322598e-15 BR00117022 P2RY12 final orf B01 U2OS 48 5000 Polylobed +0.08390986554096311 3.684104522538325e-15 BR00117023 AKT1 final orf J16 U2OS 48 4800 Polylobed +0.08599562363238512 4.0453802904792695e-15 BR00117023 CYP1A2 final orf F21 U2OS 48 4570 Polylobed +0.0757204899816795 6.271528703437927e-15 BR00117023 HSP90AB1 final orf P01 U2OS 48 5815 Polylobed +0.08348106526581774 7.562116615540213e-15 BR00117023 CACNG1 final orf E23 U2OS 48 4750 Polylobed +0.09807340152799189 8.476155553880948e-15 BR00117023 KRAS final orf F08 U2OS 48 3425 Polylobed +0.07272008768463356 8.5959687373979e-15 BR00117022 CDC25A final orf M04 U2OS 48 6235 Polylobed +0.08572839244269007 1.1630130995780819e-14 BR00117023 LYN final orf C20 U2OS 48 4450 Polylobed +0.11083573162280962 2.0027715843956723e-14 BR00117023 HSD11B1 final orf C02 U2OS 48 2615 Polylobed +0.08195725599183906 3.133141773254845e-14 BR00117023 DCK final orf D05 U2OS 48 4710 Polylobed +0.08305380101997717 4.1404252496361805e-14 BR00117023 PRKCE final orf L14 U2OS 48 4550 Polylobed +0.07545454545454545 4.897747716398407e-14 BR00117022 DDR2 final orf M02 U2OS 48 5500 Polylobed +0.0747119438775593 6.044301475815717e-14 BR00117022 CSK final orf P05 U2OS 48 5550 Polylobed +0.07799026837644746 8.077016453231122e-14 BR00117022 SIRT2 final orf A07 U2OS 48 5055 Polylobed +0.07699180340776078 8.642120980815377e-14 BR00117022 CACNA2D3 final orf L02 U2OS 48 5165 Polylobed +0.08084262865757057 8.877598227079655e-14 BR00117022 HTR3A final orf H24 U2OS 48 4690 Polylobed +0.07384341637010676 9.574880358903752e-14 BR00117022 HCK final orf O01 U2OS 48 5620 Polylobed +0.07309952982323183 1.3172996292435162e-13 BR00117023 HBB final orf C10 U2OS 48 5670 Polylobed +0.07734915924826904 1.4276113505168434e-13 BR00117023 HRH4 final orf O05 U2OS 48 5055 Polylobed +0.08207908552168393 1.5627318237885394e-13 BR00117023 HTR2C final orf M06 U2OS 48 4455 Polylobed +0.07334525939177101 1.7004176981045651e-13 BR00117023 CDK2 final orf L03 U2OS 48 5590 Polylobed +0.07819543391608258 2.4162865749253507e-13 BR00117022 SLC7A11 final orf G24 U2OS 48 4845 Polylobed +0.07673098438639114 2.933976078660261e-13 BR00117022 VEGFA final orf B09 U2OS 48 5005 Polylobed +0.08086665060718154 3.029839673832546e-13 BR00117023 SLC7A11 final orf G24 U2OS 48 4505 Polylobed +0.07872425538541651 3.3520515501849323e-13 BR00117022 CSF1R final orf D14 U2OS 48 4735 Polylobed +0.07285927893524852 3.5900103396974766e-13 BR00117022 GPR119 final orf N23 U2OS 48 5515 Polylobed +0.07110332749562172 5.680064969359393e-13 BR00117022 S100B final orf M20 U2OS 48 5710 Polylobed +0.06890508961555405 9.653452926706866e-13 BR00117023 ALDH2 final orf P13 U2OS 48 5955 Polylobed +0.08180619659057048 1.1413010063064044e-12 BR00117023 ABL1 final orf M24 U2OS 48 4190 Polylobed +0.07691909567835886 1.2870799508015097e-12 BR00117023 CLK1 final orf J17 U2OS 48 4725 Polylobed +0.07355199573836611 1.653169719043591e-12 BR00117022 OPRL1 final orf A23 U2OS 48 5125 Polylobed +0.06771509170556876 1.8820656589060854e-12 BR00117022 LCK final orf H01 U2OS 48 6030 Polylobed 0.25602976678257405 5.30011299333156e-160 BR00117023 DHH final orf G05 U2OS 48 5540 Prometaphase 0.2203125 3.11694586668797e-109 BR00117023 TUBB3 final orf K05 U2OS 48 5120 Prometaphase 0.20404714074795394 1.3577605530930845e-87 BR00117023 SLC7A11 final orf A03 U2OS 48 4780 Prometaphase @@ -1639,6 +16309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.15992647058823528 4.172471058412823e-61 BR00117023 CDC25A final orf M04 U2OS 48 5440 Prometaphase 0.17408665052895822 2.5663070247454964e-56 BR00117023 TUBB4B final orf E04 U2OS 48 4225 Prometaphase 0.15098611762486416 1.3473141477934043e-51 BR00117023 GRIN2A final orf A05 U2OS 48 5145 Prometaphase +0.182701062215478 1.8737899874776857e-48 BR00117023 PTK2B final orf J18 U2OS 48 3295 Prometaphase +0.15323053053211533 2.788829139446987e-47 BR00117023 KCNN4 final orf A06 U2OS 48 4565 Prometaphase +0.15143410843033492 2.825419093397474e-45 BR00117023 GABRB2 final orf C06 U2OS 48 4475 Prometaphase +0.13825961741353754 1.7907346713631495e-28 BR00117022 PTK2B final orf J18 U2OS 48 3365 Prometaphase +0.12401057760754354 5.5000110794315455e-24 BR00117022 KRAS final orf F08 U2OS 48 3515 Prometaphase +0.10088214021250581 7.098478413956667e-24 BR00117022 BTK final orf N01 U2OS 48 5280 Prometaphase +0.1116143182544926 6.788676702493044e-21 BR00117023 PTK2B final orf N19 U2OS 48 3770 Prometaphase +0.0938915998517805 1.4487117242394585e-19 BR00117022 PAK4 final orf G10 U2OS 48 4975 Prometaphase +0.09330354779264208 8.322450235855683e-19 BR00117022 CDK2 final orf L03 U2OS 48 4840 Prometaphase +0.09869430330550066 3.1970427203602617e-18 BR00117022 KRAS final orf D17 U2OS 48 4190 Prometaphase +0.10537595917667891 5.464052288432807e-18 BR00117022 ABL1 final orf C01 U2OS 48 3625 Prometaphase +0.09092805005213764 1.152350313436119e-17 BR00117022 P2RY12 final orf B24 U2OS 48 4795 Prometaphase +0.10188085521069301 7.49615383292588e-17 BR00117023 KRAS final orf D17 U2OS 48 3635 Prometaphase +0.08975156760002516 4.923155917183848e-16 BR00117023 CYP2A6 final orf A20 U2OS 48 4440 Prometaphase +0.10148583158020254 7.783813544524085e-16 BR00117023 KRAS final orf F08 U2OS 48 3425 Prometaphase +0.08149501392159554 4.692909733702107e-15 BR00117022 SIRT2 final orf A07 U2OS 48 5055 Prometaphase +0.0833628981393882 4.840073339413134e-15 BR00117023 AKR1C1 final orf A24 U2OS 48 4830 Prometaphase +0.07282460270792898 7.9893318538939e-15 BR00117022 CDC25A final orf M04 U2OS 48 6235 Prometaphase +0.08644510838932813 1.6572293479265564e-14 BR00117023 GPR55 final orf H16 U2OS 48 4330 Prometaphase +0.07812738959262772 2.4202486233385617e-14 BR00117023 CCND1 final orf P16 U2OS 48 5240 Prometaphase +0.08012048192771085 2.5350054361842814e-14 BR00117022 GHSR final orf C24 U2OS 48 4980 Prometaphase +0.08088762388011028 2.562261542878752e-14 BR00117022 SIRT2 final orf G02 U2OS 48 4865 Prometaphase +0.07866825473202217 9.054606986742663e-14 BR00117022 ABL1 final orf M24 U2OS 48 4940 Prometaphase +0.08795301588792484 1.318923176711361e-13 BR00117022 PTK2B final orf N19 U2OS 48 3915 Prometaphase +0.07997734683557646 1.7053780503357953e-13 BR00117022 HTR3A final orf H24 U2OS 48 4690 Prometaphase +0.07157863733788505 3.4390737545904666e-13 BR00117023 ITGB2 final orf P21 U2OS 48 5725 Prometaphase +0.0769576959539571 3.654510549094748e-13 BR00117023 PAK1 final orf L12 U2OS 48 4940 Prometaphase +0.0783342989648608 4.418186338326415e-13 BR00117022 CHRM3 final orf A10 U2OS 48 4740 Prometaphase +0.07698691890765061 8.144840736034284e-13 BR00117023 AKT1 final orf J16 U2OS 48 4800 Prometaphase +0.07186885501043705 8.17489063423166e-13 BR00117022 CSF1R final orf J07 U2OS 48 5505 Prometaphase +0.07211695334873887 9.981439476498947e-13 BR00117023 CACNB4 final orf M01 U2OS 48 5435 Prometaphase +0.07374569570398076 1.0869829043699473e-12 BR00117023 DDR2 final orf M02 U2OS 48 5180 Prometaphase +0.07453509912034798 1.5478800941855584e-12 BR00117022 VEGFA final orf B09 U2OS 48 5005 Prometaphase +0.07464503042596349 2.2979657478511287e-12 BR00117022 TUBB3 final orf K05 U2OS 48 4930 Prometaphase +0.07245226764350456 2.721431626839491e-12 BR00117022 GRIN2A final orf I24 U2OS 48 5195 Prometaphase +0.0740421150567997 2.7401868705547294e-12 BR00117022 IGF1R final orf N16 U2OS 48 4960 Prometaphase +0.07193950572186525 4.537674353411426e-12 BR00117023 CHRM3 final orf A11 U2OS 48 5170 Prometaphase +0.07939819654954931 5.7803482045723764e-12 BR00117023 KCNH7 final orf A22 U2OS 48 4190 Prometaphase +0.0704949939970276 6.1236140556504775e-12 BR00117022 TGM2 final orf B07 U2OS 48 5325 Prometaphase +0.06839892123069066 7.754324192679871e-12 BR00117022 CACNB4 final orf M01 U2OS 48 5600 Prometaphase +0.06659112252987794 1.0526042626305022e-11 BR00117022 PLK1 final orf N08 U2OS 48 5845 Prometaphase +0.07775193696868318 1.7398078103392637e-11 BR00117023 ABL1 final orf M24 U2OS 48 4190 Prometaphase +0.07417743361917942 1.789796984864404e-11 BR00117022 CATSPER4 final orf D24 U2OS 48 4615 Prometaphase +0.07247498436522827 2.026249086229265e-11 BR00117023 KCNN1 final orf A01 U2OS 48 4800 Prometaphase +0.068784172099636 4.7397988394680273e-11 BR00117022 PTPN2 final orf I02 U2OS 48 5160 Prometaphase +0.06457789382071366 7.756985901589438e-11 BR00117022 HSP90AB1 final orf P01 U2OS 48 5745 Prometaphase +0.06709537985492336 1.7384707194870874e-10 BR00117022 CASP3 final orf N05 U2OS 48 5130 Prometaphase +0.0716465997692713 2.7946165373490626e-10 BR00117023 SIRT2 final orf A07 U2OS 48 4405 Prometaphase +0.07197007937609631 2.9148787663794793e-10 BR00117022 CACNB4 final orf A18 U2OS 48 4360 Prometaphase +0.064 3.246721845650263e-10 BR00117022 DDR2 final orf M02 U2OS 48 5500 Prometaphase +0.06699003352374909 3.7789151669262867e-10 BR00117022 PAK4 final orf M19 U2OS 48 4970 Prometaphase +0.06842422005212703 4.498001908595859e-10 BR00117022 PTGIS final orf H13 U2OS 48 4730 Prometaphase +0.07134502923976609 6.978385021116624e-10 BR00117023 CA5A final orf B23 U2OS 48 4275 Prometaphase +0.06325356241313168 8.599985984406077e-10 BR00117022 OPRM1 final orf A09 U2OS 48 5375 Prometaphase +0.07077925283642109 1.2053591815558712e-09 BR00117022 CYP2A6 final orf A20 U2OS 48 4220 Prometaphase +0.06414050666891348 1.7489974352758324e-09 BR00117022 MET final orf C03 U2OS 48 5050 Prometaphase +0.06472680393012752 1.93214641686331e-09 BR00117022 CDK4 final orf B21 U2OS 48 4935 Prometaphase +0.08050995043388953 2.010196446768648e-09 BR00117022 HSD11B1 final orf C02 U2OS 48 3175 Prometaphase +0.0625242718446602 3.569472372940041e-09 BR00117022 CACNG1 final orf A16 U2OS 48 5150 Prometaphase +0.06399061341681432 3.6483096313704422e-09 BR00117023 PIK3CG final orf I03 U2OS 48 4885 Prometaphase +0.06010163535550529 4.286038616872694e-09 BR00117022 PTGIR final orf C07 U2OS 48 5505 Prometaphase +0.06554703484288638 5.304971815824359e-09 BR00117023 CLK1 final orf D08 U2OS 48 4580 Prometaphase +0.06279757038886659 6.957443933111411e-09 BR00117023 FPR1 final orf L04 U2OS 48 4920 Prometaphase +0.06430603883478943 8.114518029560975e-09 BR00117023 CACNG1 final orf A16 U2OS 48 4645 Prometaphase +0.06563691316425717 8.343406399976812e-09 BR00117023 CCR1 final orf F24 U2OS 48 4460 Prometaphase +0.06690476190476191 1.3522662288453215e-08 BR00117023 LPAR1 final orf B20 U2OS 48 4200 Prometaphase +0.06002995428679584 1.5681136997643138e-08 BR00117022 CLK1 final orf J17 U2OS 48 5170 Prometaphase +0.06128864971618492 1.8152329564222783e-08 BR00117023 AGER final orf H18 U2OS 48 4915 Prometaphase +0.06498460714763753 2.058269056234475e-08 BR00117023 PTGIS final orf F16 U2OS 48 4340 Prometaphase +0.05832300224941787 2.210070948967619e-08 BR00117022 GHSR final orf A17 U2OS 48 5370 Prometaphase +0.06126475895256035 2.3455021253391624e-08 BR00117022 SLC7A11 final orf G24 U2OS 48 4845 Prometaphase +0.057297297297297295 2.422860211799626e-08 BR00117023 KCTD16 final orf M22 U2OS 48 5550 Prometaphase +0.061360949300318844 2.7281338628033502e-08 BR00117022 BRD4 final orf F14 U2OS 48 4790 Prometaphase +0.06119255137530435 3.221056588196013e-08 BR00117023 PTGIS final orf H13 U2OS 48 4775 Prometaphase +0.06111696522655427 3.977798474461353e-08 BR00117023 GHSR final orf C24 U2OS 48 4745 Prometaphase +0.06391242735737432 4.710141275653857e-08 BR00117023 PIK3CG final orf G18 U2OS 48 4285 Prometaphase +0.060075330401355945 6.938348625170653e-08 BR00117022 HSD11B1 final orf G23 U2OS 48 4750 Prometaphase +0.05205154662362438 7.663872789607894e-08 BR00117022 P3H1 final orf P24 U2OS 48 6290 Prometaphase +0.06027662009096041 8.265121884395075e-08 BR00117022 AKT1 final orf J16 U2OS 48 4655 Prometaphase +0.05454289351223889 1.3160927972231704e-07 BR00117022 GAA final orf N04 U2OS 48 5540 Prometaphase +0.05583580063731292 1.3318731883561225e-07 BR00117023 SSTR2 final orf J01 U2OS 48 5290 Prometaphase +0.055891295663367216 1.6070083997790478e-07 BR00117022 KCNN1 final orf A01 U2OS 48 5200 Prometaphase +0.05831213482579595 1.6578476431880008e-07 BR00117022 SLC7A11 final orf A03 U2OS 48 4775 Prometaphase +0.05573239096304256 1.680450736896484e-07 BR00117022 CDC25A final orf I19 U2OS 48 5215 Prometaphase +0.05670556510892645 1.9940569734313722e-07 BR00117023 CDK4 final orf B21 U2OS 48 4995 Prometaphase +0.05637982195845697 2.0876976397962142e-07 BR00117023 HRH4 final orf O05 U2OS 48 5055 Prometaphase +0.05501387287289357 2.1639572634025362e-07 BR00117022 CDK2 final orf J04 U2OS 48 5275 Prometaphase +0.055968688845401175 2.2197596847530353e-07 BR00117022 JAK1 final orf H17 U2OS 48 5110 Prometaphase +0.055773077673692426 2.2683919770119842e-07 BR00117022 KCNN4 final orf O17 U2OS 48 5120 Prometaphase +0.05670863850044433 2.4962803540922095e-07 BR00117022 TGFBR1 final orf O14 U2OS 48 4920 Prometaphase 0.24985799285274118 2.3001208705422503e-152 BR00117023 DHH final orf G05 U2OS 48 5540 SmallIrregular 0.2699235558396995 6.144375020655552e-144 BR00117023 GABRB2 final orf C06 U2OS 48 4475 SmallIrregular 0.23799020439557952 1.0521315005804172e-140 BR00117023 ADH1C final orf O04 U2OS 48 5640 SmallIrregular @@ -1649,6 +16409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.22933484328513576 5.012132973203799e-113 BR00117023 TUBB3 final orf G06 U2OS 48 4880 SmallIrregular 0.22697335753238734 1.659081458414928e-103 BR00117023 KCNN4 final orf A06 U2OS 48 4565 SmallIrregular 0.2107421875 6.486733660604191e-100 BR00117023 TUBB3 final orf K05 U2OS 48 5120 SmallIrregular +0.19690469786623632 3.9120079267568204e-72 BR00117023 TUBB4B final orf E04 U2OS 48 4225 SmallIrregular +0.18217387573099159 9.542502573190627e-70 BR00117023 SLC7A11 final orf A03 U2OS 48 4780 SmallIrregular +0.18126330623470494 2.1691306653629573e-64 BR00117023 LYN final orf C20 U2OS 48 4450 SmallIrregular +0.15838349489264122 5.497219872997933e-53 BR00117023 LYN final orf M05 U2OS 48 4800 SmallIrregular +0.15520504731861198 2.2908478493395273e-50 BR00117022 LYN final orf C20 U2OS 48 4755 SmallIrregular +0.16259726481829428 1.9373782410648577e-46 BR00117022 LYN final orf M05 U2OS 48 3985 SmallIrregular +0.13368729457606449 2.7620810396166695e-34 BR00117023 PTGIS final orf F16 U2OS 48 4340 SmallIrregular +0.11161523147699397 2.8268140043308977e-34 BR00117022 CDC25A final orf M04 U2OS 48 6235 SmallIrregular +0.13425960128715322 6.305004388879978e-29 BR00117022 ABL1 final orf C01 U2OS 48 3625 SmallIrregular +0.12104981022454564 8.104679416160986e-29 BR00117023 CYP2A6 final orf A20 U2OS 48 4440 SmallIrregular +0.11213734743146508 8.595885828845813e-28 BR00117023 UGT1A9 final orf E24 U2OS 48 4995 SmallIrregular +0.11052790597337142 4.658416262292906e-27 BR00117023 ABL1 final orf C01 U2OS 48 5005 SmallIrregular +0.11724154274031802 2.760032739637804e-26 BR00117022 CCR1 final orf F24 U2OS 48 4310 SmallIrregular +0.10705314009661836 3.142062604650486e-26 BR00117022 CLK1 final orf D08 U2OS 48 5175 SmallIrregular +0.10579562877583437 6.79471698218658e-26 BR00117022 CDC25A final orf I19 U2OS 48 5215 SmallIrregular +0.11290538064555532 7.399761321406239e-26 BR00117023 CLK1 final orf D08 U2OS 48 4580 SmallIrregular +0.10454721094450645 1.6139331994268357e-25 BR00117023 HCK final orf O20 U2OS 48 5275 SmallIrregular +0.10336586161656576 5.428240300536029e-25 BR00117022 OPRL1 final orf O16 U2OS 48 5270 SmallIrregular +0.10791125001385334 1.4996114404901315e-24 BR00117023 CACNG1 final orf E23 U2OS 48 4750 SmallIrregular +0.14143724677099867 3.0485699403314654e-23 BR00117023 HSD11B1 final orf C02 U2OS 48 2615 SmallIrregular +0.10876616886937006 3.988039109201884e-23 BR00117023 RNASE1 final orf I18 U2OS 48 4405 SmallIrregular +0.1029630810119625 5.467459894363397e-23 BR00117022 MAPK14 final orf G15 U2OS 48 4890 SmallIrregular +0.10864458425539945 1.1166012068783045e-22 BR00117022 PTGIS final orf F16 U2OS 48 4320 SmallIrregular +0.11202071867371188 4.680486686855699e-21 BR00117023 PTK2B final orf N19 U2OS 48 3770 SmallIrregular +0.10158657219989861 1.4021767205206018e-20 BR00117023 OPRL1 final orf A23 U2OS 48 4475 SmallIrregular +0.11714719271623672 4.1742836767507263e-20 BR00117023 PTK2B final orf J18 U2OS 48 3295 SmallIrregular +0.09587164553956462 5.33159959800218e-20 BR00117023 CHEK2 final orf F07 U2OS 48 4890 SmallIrregular +0.09185081947441069 9.000918442723288e-20 BR00117022 HCK final orf O20 U2OS 48 5255 SmallIrregular +0.10602179616127698 1.314384744198508e-19 BR00117022 PTK2B final orf N19 U2OS 48 3915 SmallIrregular +0.09454563695545548 1.3940577349579994e-19 BR00117023 FPR1 final orf L04 U2OS 48 4920 SmallIrregular +0.10047670810969948 2.1347760024045895e-19 BR00117023 CYP3A4 final orf K22 U2OS 48 4305 SmallIrregular +0.09543340380549682 3.468725230133153e-19 BR00117022 PTGIS final orf H13 U2OS 48 4730 SmallIrregular +0.09498011314671895 3.762047509816094e-19 BR00117023 CSK final orf B04 U2OS 48 4765 SmallIrregular +0.09732294294498445 5.081796538414517e-19 BR00117023 SLC7A11 final orf G24 U2OS 48 4505 SmallIrregular +0.0938844426910143 5.46946462043534e-19 BR00117023 HTR2C final orf G21 U2OS 48 4840 SmallIrregular +0.10853461040162872 6.671152937120083e-19 BR00117022 DYRK1B final orf G13 U2OS 48 3600 SmallIrregular +0.09508547008547008 7.923067770577497e-19 BR00117023 PTGIR final orf E16 U2OS 48 4680 SmallIrregular +0.09606126914660831 9.123960412316401e-19 BR00117023 CYP1A2 final orf F21 U2OS 48 4570 SmallIrregular +0.0968798396578669 1.1296054846957492e-18 BR00117023 HTR2C final orf M06 U2OS 48 4455 SmallIrregular +0.08803602617040623 1.1741998034540113e-18 BR00117023 PNLIP final orf L22 U2OS 48 5405 SmallIrregular +0.0915621886651714 1.979952143903625e-18 BR00117023 KCNJ1 final orf E22 U2OS 48 4925 SmallIrregular +0.11026398942665003 2.8698120073617338e-18 BR00117022 PTK2B final orf J18 U2OS 48 3365 SmallIrregular +0.09064842085589947 3.913867508643851e-18 BR00117022 ABL1 final orf M24 U2OS 48 4940 SmallIrregular +0.09793057949159845 4.4204265855420576e-18 BR00117022 CYP2A6 final orf A20 U2OS 48 4220 SmallIrregular +0.08733765335267583 7.223406016370162e-18 BR00117023 CCND1 final orf P16 U2OS 48 5240 SmallIrregular +0.08263473053892216 8.890483312825232e-18 BR00117023 HCK final orf O01 U2OS 48 5845 SmallIrregular +0.09115044247787611 9.347480487060388e-17 BR00117022 SCNN1G final orf A04 U2OS 48 4520 SmallIrregular +0.10767505668596719 1.6748849564457525e-16 BR00117022 HSD11B1 final orf C02 U2OS 48 3175 SmallIrregular +0.081216457960644 1.8680639904832652e-16 BR00117023 CDK2 final orf L03 U2OS 48 5590 SmallIrregular +0.0880927291886196 1.9500759360247054e-16 BR00117023 GHSR final orf C24 U2OS 48 4745 SmallIrregular +0.08670428193747305 2.5677845373622095e-16 BR00117023 TUBB final orf E19 U2OS 48 4855 SmallIrregular +0.08679801269699419 3.0894925950094564e-16 BR00117023 DYRK1B final orf M12 U2OS 48 4810 SmallIrregular +0.08862940266410506 5.328943264512175e-16 BR00117023 PRKCE final orf L14 U2OS 48 4550 SmallIrregular +0.08417321096287886 1.7649495411985691e-15 BR00117023 FPR1 final orf D21 U2OS 48 4875 SmallIrregular +0.08194174757281554 1.8534952096546185e-15 BR00117022 CYP1A2 final orf F21 U2OS 48 5150 SmallIrregular +0.07314329974986225 3.631105001398062e-15 BR00117022 S1PR1 final orf L01 U2OS 48 6335 SmallIrregular +0.08128654970760234 3.674140791594107e-15 BR00117023 KCNMA1 final orf O08 U2OS 48 5130 SmallIrregular +0.08358181806227934 5.886388565088302e-15 BR00117023 PTGIS final orf H13 U2OS 48 4775 SmallIrregular +0.07960081879898351 9.515739216947188e-15 BR00117022 TUBB4B final orf E04 U2OS 48 5190 SmallIrregular +0.08311108813065478 1.5211913442136862e-14 BR00117022 FPR1 final orf L04 U2OS 48 4695 SmallIrregular +0.08182673023662423 1.7284031527885078e-14 BR00117023 AKR1B1 final orf L17 U2OS 48 4810 SmallIrregular +0.09684138353959236 1.8702759194857675e-14 BR00117023 KRAS final orf F08 U2OS 48 3425 SmallIrregular +0.0783025353532264 2.1033183345694658e-14 BR00117023 CDK2 final orf J04 U2OS 48 5240 SmallIrregular +0.0871497835616251 2.6303538319908548e-14 BR00117022 DYRK1B final orf M12 U2OS 48 4190 SmallIrregular +0.08680251892813945 3.2579291023645317e-14 BR00117023 ABL1 final orf M24 U2OS 48 4190 SmallIrregular +0.07510736587230789 3.378732921290337e-14 BR00117022 FOXM1 final orf P15 U2OS 48 5605 SmallIrregular +0.07657934510763474 4.63669286071297e-14 BR00117023 S1PR1 final orf L01 U2OS 48 5335 SmallIrregular +0.07523796004523356 5.1686295816008666e-14 BR00117022 PTGIR final orf C07 U2OS 48 5505 SmallIrregular +0.07384341637010676 9.574880358903752e-14 BR00117022 HCK final orf O01 U2OS 48 5620 SmallIrregular +0.07870930745592979 1.940747586503405e-13 BR00117023 FLT3 final orf K13 U2OS 48 4810 SmallIrregular +0.0863863246923782 3.6153414307940385e-13 BR00117023 DYRK1B final orf G13 U2OS 48 3910 SmallIrregular +0.07145359019264448 4.269042639876025e-13 BR00117022 S100B final orf M20 U2OS 48 5710 SmallIrregular +0.07453451654304159 4.4247072910966143e-13 BR00117023 CDC25A final orf I19 U2OS 48 5225 SmallIrregular +0.07179483534707415 4.596446464320499e-13 BR00117022 LCK final orf B18 U2OS 48 5625 SmallIrregular +0.08193185977932396 5.892500379684187e-13 BR00117023 PIK3CG final orf G18 U2OS 48 4285 SmallIrregular +0.07543038946505484 9.941638361988999e-13 BR00117023 IGF1R final orf H05 U2OS 48 4960 SmallIrregular +0.07640452978666272 2.4206464788530006e-12 BR00117022 RPL3 final orf G09 U2OS 48 4680 SmallIrregular +0.07736729523963029 2.9233144341478366e-12 BR00117023 F10 final orf I04 U2OS 48 4540 SmallIrregular +0.07630986834314302 2.977879187872471e-12 BR00117023 TNF final orf C18 U2OS 48 4655 SmallIrregular +0.07853242549322156 3.0183591965788323e-12 BR00117022 SCNN1G final orf O03 U2OS 48 4390 SmallIrregular +0.07906432748538011 4.833875217804558e-12 BR00117023 CA5A final orf B23 U2OS 48 4275 SmallIrregular +0.06915522478687013 5.285572756914124e-12 BR00117022 CSK final orf P05 U2OS 48 5550 SmallIrregular +0.07690914420135732 6.036486226789686e-12 BR00117023 PORCN final orf D22 U2OS 48 4470 SmallIrregular +0.0702803738317757 6.5497461222443575e-12 BR00117023 S100B final orf M20 U2OS 48 5350 SmallIrregular +0.07460484720758694 6.634537280840843e-12 BR00117023 PDPK1 final orf D06 U2OS 48 4745 SmallIrregular +0.07743270698989185 8.192596724741497e-12 BR00117022 CACNB4 final orf A18 U2OS 48 4360 SmallIrregular +0.06700658014269038 9.840519498703395e-12 BR00117023 UGT1A9 final orf O09 U2OS 48 5770 SmallIrregular +0.07339063539719605 1.4015896269193468e-11 BR00117022 CA5A final orf B23 U2OS 48 4760 SmallIrregular +0.0650984287098196 1.4157007035144573e-11 BR00117022 LCK final orf H01 U2OS 48 6030 SmallIrregular +0.07258416833454215 1.4574043691491542e-11 BR00117022 BAX final orf K17 U2OS 48 4850 SmallIrregular 0.1758240182406126 9.721034747295625e-56 BR00118039 P3H1 final orf P24 U2OS 96 4092 ADCCM 0.17191490424542144 1.6477963778645401e-49 BR00118040 KRAS final orf F08 U2OS 96 3798 ADCCM 0.14659813999021049 1.0753993273328104e-38 BR00118039 LYN final orf M05 U2OS 96 4086 ADCCM @@ -1659,6 +16509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.10759969902182091 3.328173145530358e-27 BR00118040 CACNB4 final orf A18 U2OS 96 5316 ADCCM 0.14262921770119258 3.653807920185213e-27 BR00118039 DYRK1B final orf G13 U2OS 96 3012 ADCCM 0.18109831900978327 8.775801371643656e-26 BR00118039 KCNMA1 final orf G01 U2OS 96 1764 ADCCM +0.11018056448314147 3.624231637217481e-21 BR00118040 DDR2 final orf A19 U2OS 96 3924 ADCCM +0.11232857410835619 3.9564287228994965e-21 BR00118039 KRAS final orf F08 U2OS 96 3762 ADCCM +0.10025542784163474 5.770480991662114e-21 BR00118040 CACNG1 final orf A16 U2OS 96 4698 ADCCM +0.1109978832212502 8.209852812103508e-21 BR00118040 OPRL1 final orf A23 U2OS 96 3798 ADCCM +0.07923516693031617 2.217621956744279e-19 BR00118039 KCNH7 final orf A22 U2OS 96 6924 ADCCM +0.10015081677473843 3.242202181033214e-19 BR00118039 ADA final orf P03 U2OS 96 4290 ADCCM +0.10268363416006579 3.4215615337533787e-19 BR00118040 FOXM1 final orf P15 U2OS 96 4080 ADCCM +0.1018568362936028 1.002273797790946e-18 BR00118040 SSTR2 final orf J01 U2OS 96 4044 ADCCM +0.08539984702316568 5.410572029510295e-18 BR00118039 SSTR2 final orf J01 U2OS 96 5532 ADCCM +0.10032326933126587 7.78134383806886e-18 BR00118039 HSP90AB1 final orf P01 U2OS 96 3966 ADCCM +0.10449138341435761 6.531899785693493e-17 BR00118040 NTRK1 final orf D01 U2OS 96 3468 ADCCM +0.10072661249925403 1.557844102031487e-16 BR00118039 KCNN1 final orf A01 U2OS 96 3642 ADCCM +0.14316214567552332 3.0434583436413444e-16 BR00118040 KRAS final orf D17 U2OS 96 1764 ADCCM +0.08288170140501948 5.281112559262545e-16 BR00118040 GHSR final orf A17 U2OS 96 5196 ADCCM +0.10026727361082186 1.0770365558701584e-15 BR00118040 OPRM1 final orf A08 U2OS 96 3480 ADCCM +0.0831055812200481 1.1649429150184882e-15 BR00118040 TBXAS1 final orf P23 U2OS 96 5070 ADCCM +0.08748289069900264 1.4096770211146524e-15 BR00118039 CDK4 final orf P20 U2OS 96 4542 ADCCM +0.07958548583388744 2.0422482104923257e-15 BR00118039 GPR119 final orf N23 U2OS 96 5436 ADCCM +0.11912876562071532 2.428297746837789e-15 BR00118040 LYN final orf M05 U2OS 96 2412 ADCCM +0.09236708813801048 2.4337506179816797e-15 BR00118040 CHRM3 final orf A10 U2OS 96 4002 ADCCM +0.07675375974350879 2.9632242663237982e-15 BR00118039 PTGIR final orf C07 U2OS 96 5778 ADCCM +0.08945950902878286 3.0536818304083334e-15 BR00118040 P2RY12 final orf B01 U2OS 96 4248 ADCCM +0.09068799289625241 3.1730346105578652e-15 BR00118040 CCR1 final orf P17 U2OS 96 4134 ADCCM +0.0720756364056114 5.00950209312349e-15 BR00118039 AKT1 final orf F15 U2OS 96 6450 ADCCM +0.07886814398841464 1.580010880931552e-14 BR00118040 ADA final orf P04 U2OS 96 5208 ADCCM +0.08529823283747368 2.3346071008810232e-14 BR00118040 SCNN1G final orf A04 U2OS 96 4386 ADCCM +0.07806373584930197 6.594804727225542e-14 BR00118040 KDR final orf A21 U2OS 96 5082 ADCCM +0.06971668035342529 8.291943387752113e-14 BR00118039 HPGDS final orf O21 U2OS 96 6330 ADCCM +0.06961822264998396 1.4776010050136697e-13 BR00118040 P3H1 final orf P24 U2OS 96 6234 ADCCM +0.07988638302791433 2.069987017895514e-13 BR00118040 UGT1A9 final orf E24 U2OS 96 4668 ADCCM +0.08643892339544514 5.60602898243222e-13 BR00118039 ADA final orf P04 U2OS 96 3864 ADCCM +0.08372343836534818 8.029870359782379e-13 BR00118039 HTR3A final orf H24 U2OS 96 4056 ADCCM +0.07772723954070986 9.092391336037977e-13 BR00118040 KCNH7 final orf A22 U2OS 96 4692 ADCCM +0.07812911432343149 1.932291847919634e-12 BR00118039 GRIN2A final orf A05 U2OS 96 4524 ADCCM +0.06728889348653554 7.957136989127133e-12 BR00118039 BRD4 final orf F14 U2OS 96 5778 ADCCM +0.06970762164507686 8.724471016055927e-12 BR00118040 GHSR final orf C24 U2OS 96 5364 ADCCM +0.061247623226561354 1.3227130557097837e-11 BR00118040 GLRA3 final orf K04 U2OS 96 6840 ADCCM +0.06639618257944166 1.5055996942338552e-11 BR00118040 HTR3A final orf H24 U2OS 96 5790 ADCCM +0.10753894003016327 1.813778130752934e-11 BR00118040 HSD11B1 final orf C02 U2OS 96 2190 ADCCM +0.07880567792462066 1.8643995763438154e-11 BR00118039 SIRT2 final orf A07 U2OS 96 4086 ADCCM +0.09559337361779094 1.994308045919832e-11 BR00118039 CATSPER4 final orf P07 U2OS 96 2754 ADCCM +0.06046581408928483 2.1367511397884813e-11 BR00118040 ADORA2A final orf O23 U2OS 96 6888 ADCCM +0.06907446511112714 2.7910626496602915e-11 BR00118040 EZH2 final orf D04 U2OS 96 5226 ADCCM +0.08843042450984995 3.4467477046796666e-11 BR00118040 PRKCE final orf J19 U2OS 96 3156 ADCCM +0.07102969684218267 4.573934932769248e-11 BR00118039 GJB4 final orf P08 U2OS 96 4848 ADCCM +0.0812807881773399 6.40995152540413e-11 BR00118040 KCNN4 final orf A06 U2OS 96 3654 ADCCM +0.06956020464535345 9.575163745308772e-11 BR00118040 HPGDS final orf O24 U2OS 96 4896 ADCCM +0.0698616249929243 1.0459789108946843e-10 BR00118039 S1PR1 final orf P22 U2OS 96 4830 ADCCM +0.07283529744325731 1.0521964044524099e-10 BR00118039 LCK final orf H01 U2OS 96 4452 ADCCM +0.0646716865436501 1.1224210015660454e-10 BR00118039 ANXA1 final orf D23 U2OS 96 5628 ADCCM +0.06845157822542114 1.2244024981757754e-10 BR00118039 LPAR1 final orf B05 U2OS 96 4992 ADCCM +0.06133651776166721 1.494670049843797e-10 BR00118040 PTGIS final orf F16 U2OS 96 6180 ADCCM +0.060562749945191605 1.706091847285445e-10 BR00118039 FFAR4 final orf C17 U2OS 96 6300 ADCCM +0.0631376860511842 2.135504904565614e-10 BR00118039 MAPK14 final orf G22 U2OS 96 5748 ADCCM +0.07265422581615093 2.2036653451245626e-10 BR00118040 COMT final orf B10 U2OS 96 4332 ADCCM +0.06194389991559803 2.3802085178948287e-10 BR00118040 S1PR4 final orf M17 U2OS 96 5940 ADCCM +0.06428916475766855 2.989543940090067e-10 BR00118040 ADRA2B final orf J03 U2OS 96 5466 ADCCM +0.08188061194093366 2.99939692793832e-10 BR00118040 SLC7A11 final orf A03 U2OS 96 3360 ADCCM +0.06972696883886247 3.313501164203155e-10 BR00118040 HIF1A final orf A12 U2OS 96 4614 ADCCM +0.05835932857991682 4.0835575294103443e-10 BR00118039 HDAC6 final orf E20 U2OS 96 6534 ADCCM +0.06724778521706534 4.168566944992316e-10 BR00118040 CSK final orf B04 U2OS 96 4902 ADCCM +0.06274301873453517 4.189416095756305e-10 BR00118040 S1PR1 final orf P22 U2OS 96 5658 ADCCM +0.058418618255226776 4.902539377831109e-10 BR00118039 KCNJ1 final orf E22 U2OS 96 6468 ADCCM +0.08271144278606965 5.452267972025433e-10 BR00118039 PRKCE final orf L14 U2OS 96 3216 ADCCM +0.05888370038012387 6.551145227618595e-10 BR00118039 CTSG final orf F19 U2OS 96 6276 ADCCM +0.07232704402515723 7.980011319316573e-10 BR00118039 KDR final orf A21 U2OS 96 4134 ADCCM +0.0712423542204703 9.979795901700335e-10 BR00118040 CDK4 final orf P20 U2OS 96 4200 ADCCM +0.07965071920893482 1.1984671829350175e-09 BR00118040 DYRK1B final orf G13 U2OS 96 3336 ADCCM +0.07146317829457365 1.3762391909304577e-09 BR00118040 AKR1C1 final orf A24 U2OS 96 4128 ADCCM +0.05609220499376475 1.383238148237197e-09 BR00118039 KCTD16 final orf K21 U2OS 96 6678 ADCCM +0.08340533614054949 3.012924716632189e-09 BR00118040 GJB4 final orf P08 U2OS 96 2898 ADCCM +0.05694187751580924 3.0750287796428518e-09 BR00118040 HTR2C final orf G21 U2OS 96 6228 ADCCM +0.06733780760626398 3.110114689809072e-09 BR00118039 LPAR1 final orf B20 U2OS 96 4470 ADCCM +0.06616279858849076 3.1871551262266717e-09 BR00118040 TUBB3 final orf K05 U2OS 96 4608 ADCCM +0.07969639468690702 3.723979322111179e-09 BR00118040 ABL1 final orf C01 U2OS 96 3162 ADCCM +0.06930209858467545 5.5914525176200205e-09 BR00118040 COMT final orf P09 U2OS 96 4098 ADCCM +0.0720192440901248 5.812781051603267e-09 BR00118039 CYP2A6 final orf A15 U2OS 96 3780 ADCCM +0.05936211271599193 7.456966825289879e-09 BR00118040 LCK final orf B18 U2OS 96 5484 ADCCM +0.06709609359174364 7.907007168383011e-09 BR00118040 HTR2C final orf M06 U2OS 96 4272 ADCCM +0.06352201257861635 8.656408057835095e-09 BR00118039 CLK1 final orf J17 U2OS 96 4770 ADCCM +0.1 8.929037609598905e-09 BR00118039 SLCO2B1 final orf A02 U2OS 96 1920 ADCCM +0.07746503747624621 9.13422718558933e-09 BR00118039 PTK2B final orf J18 U2OS 96 3192 ADCCM +0.06182472989195678 9.997123730596418e-09 BR00118039 SLC7A11 final orf A03 U2OS 96 4998 ADCCM +0.06377082840204114 1.0798572834602865e-08 BR00118039 CACNB4 final orf A18 U2OS 96 4668 ADCCM +0.05351320219741272 1.5995967922068095e-08 BR00118040 CACNG1 final orf E23 U2OS 96 6480 ADCCM +0.05967298971705946 1.611024150689532e-08 BR00118040 FPR1 final orf L04 U2OS 96 5220 ADCCM +0.05573978680010933 1.639240867745889e-08 BR00118040 P2RY12 final orf B24 U2OS 96 5970 ADCCM +0.05040971770991264 1.690494989734774e-08 BR00118040 MAPK14 final orf G22 U2OS 96 7296 ADCCM +0.06873990588008996 1.7531013705696528e-08 BR00118039 NTRK1 final orf D01 U2OS 96 3918 ADCCM +0.06656276153249513 1.9833881405362393e-08 BR00118040 CACNB4 final orf M01 U2OS 96 4152 ADCCM 0.21532053603766751 1.3215071078398308e-61 BR00118039 DYRK1B final orf G13 U2OS 96 3012 Anaphase 0.260127217415353 1.7523918323068305e-58 BR00118039 DYRK1B final orf M12 U2OS 96 1950 Anaphase 0.17235474652033916 8.213569031012361e-44 BR00118040 DYRK1B final orf G13 U2OS 96 3336 Anaphase @@ -1669,6 +16609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.10577110501706552 1.9994715670697865e-19 BR00118040 GJB4 final orf H23 U2OS 96 3900 Anaphase 0.09645580978017047 1.829055764032142e-18 BR00118040 CDK7 final orf K06 U2OS 96 4458 Anaphase 0.13774057171159698 3.6056877083246536e-17 BR00118040 KCNN1 final orf A01 U2OS 96 2016 Anaphase +0.1080347854936796 6.835429106734318e-17 BR00118040 CCND1 final orf P16 U2OS 96 3228 Anaphase +0.10081614430345977 1.406603992894656e-16 BR00118040 ADRA2B final orf N18 U2OS 96 3636 Anaphase +0.09583773471924373 1.90382895160525e-16 BR00118040 CHRM3 final orf A10 U2OS 96 4002 Anaphase +0.08684546615581099 7.851217661406158e-16 BR00118040 CACNG1 final orf A16 U2OS 96 4698 Anaphase +0.07145683672226957 1.0121650543342581e-15 BR00118039 FGF1 final orf F22 U2OS 96 6876 Anaphase +0.09430512016718913 3.1317732091568018e-15 BR00118040 ADA final orf P03 U2OS 96 3828 Anaphase +0.08322374478578691 3.330472301195391e-15 BR00118040 HPGDS final orf O24 U2OS 96 4896 Anaphase +0.07590444778505046 4.98311603678436e-15 BR00118039 TUBB final orf E19 U2OS 96 5814 Anaphase +0.08893762183235868 1.5344091376602038e-14 BR00118039 CACNB4 final orf M01 U2OS 96 4104 Anaphase +0.07967677841077454 1.7390448989935034e-14 BR00118040 SCNN1G final orf O03 U2OS 96 5082 Anaphase +0.08549954364202977 3.518592524016313e-14 BR00118040 BTK final orf N01 U2OS 96 4314 Anaphase +0.08137705531671281 6.802866476503088e-14 BR00118040 UGT1A9 final orf E24 U2OS 96 4668 Anaphase +0.07316649287452207 8.177499733143734e-14 BR00118040 SLC7A11 final orf G24 U2OS 96 5754 Anaphase +0.07603686635944701 1.6322695512353744e-13 BR00118039 CDK2 final orf L03 U2OS 96 5208 Anaphase +0.08600298358878028 2.0075183131077758e-13 BR00118039 DCK final orf L18 U2OS 96 4026 Anaphase +0.08489588257333039 2.0702686709992625e-13 BR00118040 RET final orf E03 U2OS 96 4140 Anaphase +0.06454215863449295 2.5574057384223785e-13 BR00118039 GHSR final orf C24 U2OS 96 7116 Anaphase +0.08806923552441788 2.9519969768916117e-13 BR00118040 KRAS final orf F08 U2OS 96 3798 Anaphase +0.09617942338685896 3.508680419653299e-13 BR00118040 PRKCE final orf J19 U2OS 96 3156 Anaphase +0.07312103100864928 4.4998479674908756e-13 BR00118040 KCNQ2 final orf K01 U2OS 96 5436 Anaphase +0.08272015191075244 5.611436493139261e-13 BR00118040 PPAT final orf H14 U2OS 96 4212 Anaphase +0.07962680599952908 9.613920827036528e-13 BR00118039 LCK final orf H01 U2OS 96 4452 Anaphase +0.0759470225310735 1.071382231981762e-12 BR00118040 ANXA1 final orf N24 U2OS 96 4878 Anaphase +0.07987665931145843 1.938989717060438e-12 BR00118040 CHRM3 final orf A11 U2OS 96 4314 Anaphase +0.07683555140090878 2.0562867334864345e-12 BR00118039 CHRM3 final orf A11 U2OS 96 4662 Anaphase +0.08152436082971538 2.0994256426167502e-12 BR00118040 PLD1 final orf L05 U2OS 96 4146 Anaphase +0.07679107679107679 2.2452955219924783e-12 BR00118040 PRKCB final orf K19 U2OS 96 4662 Anaphase +0.07745821386828652 3.1159081909217194e-12 BR00118039 GRIN2A final orf A05 U2OS 96 4524 Anaphase +0.08 3.733086442220391e-12 BR00118040 CDK4 final orf P20 U2OS 96 4200 Anaphase +0.08076358296622614 5.1883087916280645e-12 BR00118039 LYN final orf M05 U2OS 96 4086 Anaphase +0.08673469387755102 5.7762194456723795e-12 BR00118040 IMPDH1 final orf L13 U2OS 96 3528 Anaphase +0.06274131992430847 5.7850615242519824e-12 BR00118040 USP1 final orf G11 U2OS 96 6720 Anaphase +0.08566193607251595 1.462437843951614e-11 BR00118040 OPRM1 final orf A08 U2OS 96 3480 Anaphase +0.07083049219687876 2.3035692090744078e-11 BR00118040 BRD4 final orf F14 U2OS 96 4998 Anaphase +0.07639079937322824 3.0421107501264436e-11 BR00118040 P2RY12 final orf B01 U2OS 96 4248 Anaphase +0.07989941700301108 3.23986471937288e-11 BR00118040 CATSPER4 final orf P07 U2OS 96 3870 Anaphase +0.07586848956775873 4.3860312738472e-11 BR00118040 NTRK1 final orf P02 U2OS 96 4248 Anaphase +0.07612860697929809 6.168029963017368e-11 BR00118040 GAA final orf N04 U2OS 96 4164 Anaphase +0.0670749880247718 6.743330273690376e-11 BR00118040 HSP90AB1 final orf P01 U2OS 96 5334 Anaphase +0.0719680579048818 7.439351528698951e-11 BR00118040 CDC25A final orf M04 U2OS 96 4620 Anaphase +0.06917077175697865 1.4802657661010355e-10 BR00118039 MAPK14 final orf G15 U2OS 96 4872 Anaphase +0.05953474135292317 1.7298916836479022e-10 BR00118040 TUBB final orf E19 U2OS 96 6534 Anaphase +0.07175759067758065 1.7873172016673373e-10 BR00118040 BRAF final orf C05 U2OS 96 4470 Anaphase +0.056428666507545994 1.861552378157673e-10 BR00118039 OPRM1 final orf A08 U2OS 96 7230 Anaphase +0.06356084290031783 1.9259673636085508e-10 BR00118040 CDK2 final orf L03 U2OS 96 5682 Anaphase +0.06783528882976397 3.2074773573070074e-10 BR00118040 DDR2 final orf M02 U2OS 96 4884 Anaphase +0.060999000374859426 3.21400712862287e-10 BR00118039 CDC25A final orf M04 U2OS 96 6042 Anaphase +0.06015727433033576 3.5477673641585106e-10 BR00118040 PTGIS final orf F16 U2OS 96 6180 Anaphase +0.060900254761816285 5.657930924724091e-10 BR00118040 PIK3CG final orf I03 U2OS 96 5904 Anaphase +0.34863672814755414 6.192666254714902e-10 BR00118040 GRIN2A final orf A05 U2OS 96 174 Anaphase +0.07670943476281607 6.632524895585358e-10 BR00118039 IMPDH1 final orf N20 U2OS 96 3684 Anaphase +0.05560295790671217 7.160453007274835e-10 BR00118039 CDC25A final orf I19 U2OS 96 7032 Anaphase +0.0688976377952756 7.39954387898959e-10 BR00118039 PPAT final orf H14 U2OS 96 4572 Anaphase +0.07278980965983618 8.373199516545373e-10 BR00118039 HTR3A final orf H24 U2OS 96 4056 Anaphase +0.07522323396430776 9.816767724405992e-10 BR00118039 CYP2A6 final orf A15 U2OS 96 3780 Anaphase +0.06041666666666667 1.4629161528400419e-09 BR00118039 SIRT2 final orf G02 U2OS 96 5760 Anaphase +0.06181619256017506 1.5671698303624318e-09 BR00118039 GRIN2A final orf I24 U2OS 96 5484 Anaphase +0.07443893901077477 1.5983537931112603e-09 BR00118040 SLCO2B1 final orf A02 U2OS 96 3762 Anaphase +0.06923429619440624 1.6377474073733534e-09 BR00118040 CYP1A2 final orf N12 U2OS 96 4362 Anaphase +0.05978089930877819 1.650532626212752e-09 BR00118039 SLC7A11 final orf G24 U2OS 96 5844 Anaphase +0.0755336617405583 1.7369211869025922e-09 BR00118040 KCNN4 final orf A06 U2OS 96 3654 Anaphase +0.06902620592239037 1.7861072228412103e-09 BR00118040 VEGFA final orf P18 U2OS 96 4356 Anaphase +0.0649835241685039 1.8616615337932362e-09 BR00118039 CATSPER4 final orf D24 U2OS 96 4902 Anaphase +0.061712268816090626 1.959254581668252e-09 BR00118040 PIK3CG final orf G18 U2OS 96 5436 Anaphase +0.05455066388856275 2.0465550809108516e-09 BR00118039 KCNH7 final orf A22 U2OS 96 6924 Anaphase +0.06178489702517163 4.003875975048557e-09 BR00118039 PDE4D final orf B17 U2OS 96 5244 Anaphase +0.06396614228401531 4.497676588658591e-09 BR00118039 FFAR4 final orf I16 U2OS 96 4854 Anaphase +0.06006082535331675 4.5091137880780004e-09 BR00118040 USP1 final orf E12 U2OS 96 5502 Anaphase +0.0594111517382001 4.559848065049739e-09 BR00118040 RPL3 final orf G09 U2OS 96 5628 Anaphase +0.05733333333333333 5.390149873850978e-09 BR00118040 PRKCB final orf K14 U2OS 96 6000 Anaphase +0.06153059477577647 6.123251614382738e-09 BR00118039 CA5A final orf B23 U2OS 96 5160 Anaphase +0.07033639143730887 7.3156083116840924e-09 BR00118039 PPARD final orf I12 U2OS 96 3924 Anaphase +0.05910713646078349 8.766693507773342e-09 BR00118039 BTK final orf N01 U2OS 96 5490 Anaphase +0.06836765634598801 8.79061770484209e-09 BR00118040 SIRT2 final orf A07 U2OS 96 4092 Anaphase +0.06440382941688425 1.039949133361888e-08 BR00118040 KDR final orf O02 U2OS 96 4596 Anaphase +0.06822346304231773 1.0670611572314062e-08 BR00118040 FOXM1 final orf P15 U2OS 96 4080 Anaphase +0.06959424756034925 1.2724705084967589e-08 BR00118040 CYP2A6 final orf A20 U2OS 96 3894 Anaphase +0.0576175326970661 1.379565020733625e-08 BR00118040 ITGB2 final orf B12 U2OS 96 5658 Anaphase +0.0548604427333975 1.4100720681926107e-08 BR00118040 P3H1 final orf P24 U2OS 96 6234 Anaphase +0.05439719248024278 1.425833712484301e-08 BR00118039 HTR3A final orf J23 U2OS 96 6330 Anaphase +0.05052229983394701 1.555765360294722e-08 BR00118040 MAPK14 final orf G22 U2OS 96 7296 Anaphase +0.06374839819443322 1.599191308548255e-08 BR00118039 HSD11B1 final orf C02 U2OS 96 4560 Anaphase +0.06682873268228423 1.6892263736202165e-08 BR00118040 CACNB4 final orf M01 U2OS 96 4152 Anaphase +0.07815873732467508 2.0670038544116394e-08 BR00118039 ALDH2 final orf P14 U2OS 96 2988 Anaphase +0.05814123943304404 2.0886367429920447e-08 BR00118040 BRAF final orf I10 U2OS 96 5412 Anaphase +0.0520368718406185 2.4450118220664386e-08 BR00118039 OPRL1 final orf O16 U2OS 96 6726 Anaphase +0.0588557867473015 2.7316729358042844e-08 BR00118040 ADA final orf P04 U2OS 96 5208 Anaphase +0.05273309020600892 3.082414246819939e-08 BR00118039 AKT1 final orf F15 U2OS 96 6450 Anaphase +0.05915347139179667 3.259293366261586e-08 BR00118040 RNASE1 final orf I18 U2OS 96 5106 Anaphase +0.05295584432872124 3.442240879995935e-08 BR00118040 PAK4 final orf M19 U2OS 96 6354 Anaphase 0.17699762526325558 1.5097354001656466e-59 BR00118040 CHRM3 final orf A11 U2OS 96 4314 Apoptosis 0.1957505082523258 6.436967991883377e-51 BR00118039 DYRK1B final orf G13 U2OS 96 3012 Apoptosis 0.15179970994142714 1.5851861180441776e-44 BR00118040 SCNN1G final orf A04 U2OS 96 4386 Apoptosis @@ -1679,6 +16709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.15130328331702522 9.46293244325805e-34 BR00118040 DYRK1B final orf G13 U2OS 96 3336 Apoptosis 0.1375735526388268 1.7910942813740695e-33 BR00118040 CHRM3 final orf A10 U2OS 96 4002 Apoptosis 0.142296918767507 6.380944213612126e-32 BR00118039 AKR1B1 final orf L17 U2OS 96 3570 Apoptosis +0.12461248241150316 1.6921816717717115e-29 BR00118039 ADA final orf P03 U2OS 96 4290 Apoptosis +0.1334517529662174 8.914177484027089e-29 BR00118039 KCNN1 final orf A01 U2OS 96 3642 Apoptosis +0.11223706540774975 9.517828538647273e-29 BR00118039 DDR2 final orf M02 U2OS 96 5154 Apoptosis +0.13136288998357964 6.94092974783957e-28 BR00118040 KCNN4 final orf A06 U2OS 96 3654 Apoptosis +0.13240605754068607 4.693013942138108e-27 BR00118040 OPRM1 final orf A08 U2OS 96 3480 Apoptosis +0.1849784181550032 6.803710725427093e-27 BR00118039 KCNMA1 final orf G01 U2OS 96 1764 Apoptosis +0.10052489475460503 1.6975322344657906e-26 BR00118040 PAK4 final orf G10 U2OS 96 5928 Apoptosis +0.12522838107012843 2.1939833699798684e-26 BR00118040 OPRL1 final orf A23 U2OS 96 3798 Apoptosis +0.11338772601597663 7.36931359305437e-26 BR00118039 CDK4 final orf P20 U2OS 96 4542 Apoptosis +0.09195402298850575 9.72711705059745e-25 BR00118039 GABRB2 final orf C19 U2OS 96 6612 Apoptosis +0.11812540174136621 2.376256178346283e-24 BR00118040 DDR2 final orf A19 U2OS 96 3924 Apoptosis +0.09187442509766576 3.965376999893483e-24 BR00118039 AKT1 final orf F15 U2OS 96 6450 Apoptosis +0.1138743867979033 8.488646952012277e-24 BR00118040 RET final orf E03 U2OS 96 4140 Apoptosis +0.11422179839247432 1.0043277903803834e-23 BR00118039 P3H1 final orf P24 U2OS 96 4092 Apoptosis +0.16666666666666666 1.0872540908085939e-23 BR00118039 SLCO2B1 final orf A02 U2OS 96 1920 Apoptosis +0.1254101238350568 1.85674767473454e-23 BR00118040 SLC7A11 final orf A03 U2OS 96 3360 Apoptosis +0.11976570680386556 5.849384325492589e-23 BR00118040 ELANE final orf D19 U2OS 96 3606 Apoptosis +0.11217973008423937 1.0380229855818074e-22 BR00118039 HTR3A final orf H24 U2OS 96 4056 Apoptosis +0.1058017055180976 1.5501712096189759e-22 BR00118039 GRIN2A final orf A05 U2OS 96 4524 Apoptosis +0.10567926802126598 2.1911636631444787e-22 BR00118040 SIRT2 final orf G02 U2OS 96 4518 Apoptosis +0.10312397499338002 3.6071084507698858e-22 BR00118040 KCNH7 final orf A22 U2OS 96 4692 Apoptosis +0.09707459873257063 9.862738601025172e-22 BR00118040 GHSR final orf A17 U2OS 96 5196 Apoptosis +0.10916179337231968 1.0526928347791783e-21 BR00118039 CACNB4 final orf M01 U2OS 96 4104 Apoptosis +0.10036778112158436 1.1006042471366583e-20 BR00118040 HIF1A final orf A12 U2OS 96 4614 Apoptosis +0.08494581975465416 1.3970153787490093e-20 BR00118039 P3H1 final orf F23 U2OS 96 6408 Apoptosis +0.10646108663729809 1.4220447712287035e-20 BR00118039 SIRT2 final orf A07 U2OS 96 4086 Apoptosis +0.11394557823129252 2.3294228507745832e-20 BR00118040 IMPDH1 final orf L13 U2OS 96 3528 Apoptosis +0.10855956499455442 2.4010955095058355e-20 BR00118040 CYP2A6 final orf A15 U2OS 96 3870 Apoptosis +0.097342470797794 5.793047658328443e-20 BR00118039 CYP2A6 final orf A20 U2OS 96 4734 Apoptosis +0.08854530518622014 1.2179057337166556e-19 BR00118039 AKT1 final orf J16 U2OS 96 5628 Apoptosis +0.09819462791721709 1.7889906337756483e-19 BR00118040 PLA2G1B final orf E06 U2OS 96 4542 Apoptosis +0.09853748016674198 2.364777033375466e-19 BR00118040 BRAF final orf C05 U2OS 96 4470 Apoptosis +0.09283713485394157 3.699025616429144e-19 BR00118039 SLC7A11 final orf A03 U2OS 96 4998 Apoptosis +0.09627250002567031 5.887181786298626e-19 BR00118040 MET final orf C03 U2OS 96 4584 Apoptosis +0.0896663668140861 1.5143920577667706e-18 BR00118039 EDNRB final orf M08 U2OS 96 5178 Apoptosis +0.07726933706829288 2.373417141387769e-18 BR00118040 ADORA2A final orf O23 U2OS 96 6888 Apoptosis +0.08800639460671929 5.114083473437675e-18 BR00118040 ADA final orf P04 U2OS 96 5208 Apoptosis +0.08741018252682149 6.303438202224118e-18 BR00118039 TNNC1 final orf M18 U2OS 96 5256 Apoptosis +0.08575192196639018 6.958275534978832e-18 BR00118039 HCK final orf O01 U2OS 96 5454 Apoptosis +0.07860523743376036 7.67576642722424e-18 BR00118040 CACNG1 final orf E23 U2OS 96 6480 Apoptosis +0.09274820168295331 1.105588499369161e-17 BR00118040 TUBB3 final orf K05 U2OS 96 4608 Apoptosis +0.09598339772496202 1.673330553019088e-17 BR00118040 P2RY12 final orf B01 U2OS 96 4248 Apoptosis +0.09762507069735368 2.119894556203539e-17 BR00118040 SIRT2 final orf A07 U2OS 96 4092 Apoptosis +0.07741366604250242 2.7092085187300798e-17 BR00118039 KCNJ1 final orf E22 U2OS 96 6468 Apoptosis +0.10031347962382445 3.5145405604784425e-17 BR00118040 ADA final orf P03 U2OS 96 3828 Apoptosis +0.07635360599723451 7.269625056773564e-17 BR00118039 PDE7A final orf F20 U2OS 96 6480 Apoptosis +0.08939974457215837 9.421898640671044e-17 BR00118040 CACNG1 final orf A16 U2OS 96 4698 Apoptosis +0.08654054752196415 2.363736268489372e-16 BR00118039 KCNN4 final orf A06 U2OS 96 4878 Apoptosis +0.07289206136612687 2.399215350081816e-16 BR00118039 FGF1 final orf F22 U2OS 96 6876 Apoptosis +0.07565917492572517 3.7134213406934706e-16 BR00118039 FFAR4 final orf C17 U2OS 96 6300 Apoptosis +0.0855596321828037 4.803503074708363e-16 BR00118040 F10 final orf I04 U2OS 96 4896 Apoptosis +0.08176541549033355 5.621310637628912e-16 BR00118040 MET final orf C08 U2OS 96 5340 Apoptosis +0.09113001454807573 7.188636050540909e-16 BR00118040 HTR2C final orf M06 U2OS 96 4272 Apoptosis +0.0819148490050759 7.499693198972948e-16 BR00118040 HDAC6 final orf K03 U2OS 96 5268 Apoptosis +0.07764232672287047 9.745732080583926e-16 BR00118039 DCK final orf D05 U2OS 96 5838 Apoptosis +0.09494324045407637 1.277182638797443e-15 BR00118040 OPRM1 final orf A09 U2OS 96 3876 Apoptosis +0.09447984690354529 1.4109492079551508e-15 BR00118040 KCNMA1 final orf G01 U2OS 96 3900 Apoptosis +0.08546814706351871 2.6795872361795067e-15 BR00118040 UGT1A9 final orf E24 U2OS 96 4668 Apoptosis +0.08549484080713958 2.8744783136025633e-15 BR00118039 CHRM3 final orf A11 U2OS 96 4662 Apoptosis +0.0924155396455663 3.2675940311650927e-15 BR00118039 HSP90AB1 final orf P01 U2OS 96 3966 Apoptosis +0.08263555431764312 4.835944579461432e-15 BR00118039 TGFBR1 final orf O14 U2OS 96 4908 Apoptosis +0.08889558367365157 6.3175250702146696e-15 BR00118040 PPAT final orf H14 U2OS 96 4212 Apoptosis +0.07680533147647947 6.986928783779741e-15 BR00118039 ANXA1 final orf D23 U2OS 96 5628 Apoptosis +0.09628507709501727 2.2002956345423843e-14 BR00118040 PTGIS final orf H13 U2OS 96 3444 Apoptosis +0.10506763975869948 2.3368712962935005e-14 BR00118040 GJB4 final orf P08 U2OS 96 2898 Apoptosis +0.06809565470982794 3.0233609429704394e-14 BR00118039 CDK7 final orf M21 U2OS 96 6858 Apoptosis +0.08430940241605805 3.945791804735155e-14 BR00118040 PTPN2 final orf I02 U2OS 96 4428 Apoptosis +0.07821025534391074 5.0725904717873194e-14 BR00118040 RNASE1 final orf I18 U2OS 96 5106 Apoptosis +0.0869670542635659 5.325392771393133e-14 BR00118040 AKR1C1 final orf A24 U2OS 96 4128 Apoptosis +0.07358289161700218 6.479076934875403e-14 BR00118039 P2RY12 final orf B01 U2OS 96 5724 Apoptosis +0.0817124990023574 7.429088952613029e-14 BR00118040 MMP2 final orf F06 U2OS 96 4614 Apoptosis +0.07557557182033381 8.87502868807706e-14 BR00118040 GHSR final orf C24 U2OS 96 5364 Apoptosis +0.10644699494014563 9.181187500910087e-14 BR00118040 DYRK1B final orf M12 U2OS 96 2700 Apoptosis +0.08611514271891631 9.375174110150927e-14 BR00118039 KDR final orf A21 U2OS 96 4134 Apoptosis +0.08430478358200438 9.639804916627273e-14 BR00118039 BTK final orf P10 U2OS 96 4290 Apoptosis +0.08934169278996865 1.0357470129931439e-13 BR00118039 RGS4 final orf D20 U2OS 96 3828 Apoptosis +0.08424462281646414 1.0422681178519184e-13 BR00118040 MMP2 final orf J15 U2OS 96 4302 Apoptosis +0.06679417577117211 1.0474842933078212e-13 BR00118039 HCK final orf O20 U2OS 96 6834 Apoptosis +0.09216220021589148 1.1108391024045544e-13 BR00118040 PDE7A final orf J11 U2OS 96 3576 Apoptosis +0.10232976995299095 1.1962208230567733e-13 BR00118040 AGER final orf H09 U2OS 96 2892 Apoptosis +0.06814974612434506 1.2275413936814306e-13 BR00118039 HDAC6 final orf E20 U2OS 96 6534 Apoptosis +0.08254822790489008 1.2433751669817555e-13 BR00118040 CDK7 final orf K06 U2OS 96 4458 Apoptosis +0.07850943562398417 1.3913446864175022e-13 BR00118040 HPGDS final orf O24 U2OS 96 4896 Apoptosis +0.06686621069283251 1.9347817604431732e-13 BR00118039 KCTD16 final orf K21 U2OS 96 6678 Apoptosis +0.06876482065864738 2.3483254471467417e-13 BR00118039 GPR55 final orf F13 U2OS 96 6288 Apoptosis +0.07510747214577154 2.367530973051536e-13 BR00118040 TNF final orf C13 U2OS 96 5256 Apoptosis +0.08663716715092658 2.3786235037058676e-13 BR00118040 CCND1 final orf B11 U2OS 96 3942 Apoptosis +0.07568456430264095 2.661768960721166e-13 BR00118039 CA5A final orf B23 U2OS 96 5160 Apoptosis +0.08422373326017966 2.7304604349260564e-13 BR00118040 CACNB4 final orf M01 U2OS 96 4152 Apoptosis +0.06966403162055336 3.1187084210781495e-13 BR00118040 CLK1 final orf D08 U2OS 96 6072 Apoptosis 0.884121892542101 4.508535155343023e-71 BR00118040 GRIN2A final orf A05 U2OS 96 174 Binuclear 0.1430442794184906 2.4183442278806548e-27 BR00118039 DYRK1B final orf G13 U2OS 96 3012 Binuclear 0.16276402383366464 4.387427146328207e-25 BR00118040 PTK2B final orf J18 U2OS 96 2124 Binuclear @@ -1689,6 +16809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.07039872652858556 1.435390343425982e-15 BR00118039 CHRM2 final orf B08 U2OS 96 7020 Binuclear 0.07269666360575451 1.9604583561387375e-15 BR00118040 TUBB final orf E19 U2OS 96 6534 Binuclear 0.07382050809893659 9.28768806602754e-15 BR00118039 CDC25A final orf M04 U2OS 96 6042 Binuclear +0.07644503507769887 9.545610683006714e-15 BR00118039 AKT1 final orf J16 U2OS 96 5628 Binuclear +0.0923183890703803 8.327723921941154e-14 BR00118040 ELANE final orf D19 U2OS 96 3606 Binuclear +0.08511017504052999 1.780190852213242e-13 BR00118040 RET final orf E03 U2OS 96 4140 Binuclear +0.08052181736392262 5.882388332177412e-13 BR00118040 CDC25A final orf I19 U2OS 96 4446 Binuclear +0.09647825158109857 1.5437649004950224e-12 BR00118039 ALDH2 final orf P14 U2OS 96 2988 Binuclear +0.06535602201985903 1.7907861118556369e-12 BR00118040 CACNG1 final orf E23 U2OS 96 6480 Binuclear +0.06441823255466123 2.201957443585093e-12 BR00118040 MAPK14 final orf G15 U2OS 96 6606 Binuclear +0.08126794093444674 4.645860070077609e-12 BR00118040 SSTR2 final orf J01 U2OS 96 4044 Binuclear +0.06909888195933592 4.686965609524831e-12 BR00118040 CDK2 final orf J04 U2OS 96 5580 Binuclear +0.08328618973580852 6.696609002370428e-12 BR00118040 KRAS final orf F08 U2OS 96 3798 Binuclear +0.06109652960046661 1.5038929693996413e-11 BR00118039 CDK7 final orf M21 U2OS 96 6858 Binuclear +0.061843416836820334 1.9075481992177514e-11 BR00118039 CDK2 final orf J04 U2OS 96 6606 Binuclear +0.06182084679508092 4.234597359219607e-11 BR00118039 P3H1 final orf F23 U2OS 96 6408 Binuclear +0.09859185194373658 6.449982728461554e-11 BR00118039 IGF1R final orf H05 U2OS 96 2478 Binuclear +0.06689549947451574 7.162321170518407e-11 BR00118040 CHRM2 final orf B08 U2OS 96 5346 Binuclear +0.07937763713080169 8.222880262817902e-11 BR00118039 DNMT3A final orf H07 U2OS 96 3792 Binuclear +0.05634418426825041 9.86308802980205e-11 BR00118039 CYP3A4 final orf K22 U2OS 96 7452 Binuclear +0.06826028968528551 1.0246405150967247e-10 BR00118040 TBXAS1 final orf P23 U2OS 96 5070 Binuclear +0.05745164960182025 1.6444390897009443e-10 BR00118039 CDC25A final orf I19 U2OS 96 7032 Binuclear +0.07093124456048738 1.783370272678382e-10 BR00118040 KDR final orf O02 U2OS 96 4596 Binuclear +0.07002979991485739 1.9401843213178685e-10 BR00118040 TNF final orf C18 U2OS 96 4698 Binuclear +0.06228090277347669 2.0601586403443524e-10 BR00118040 ADORA2A final orf O18 U2OS 96 5904 Binuclear +0.06729987995198079 2.680430930973933e-10 BR00118040 BRD4 final orf F14 U2OS 96 4998 Binuclear +0.08174026367303679 3.772827692792582e-10 BR00118040 IGF1R final orf N16 U2OS 96 3330 Binuclear +0.065738592420727 3.8725588499424017e-10 BR00118040 AKR1C1 final orf I01 U2OS 96 5172 Binuclear +0.05792498487598306 4.585899287867004e-10 BR00118039 GABRB2 final orf C19 U2OS 96 6612 Binuclear +0.06926065418023887 4.675098088767691e-10 BR00118040 TUBB3 final orf K05 U2OS 96 4608 Binuclear +0.06559011164274323 8.385531223366928e-10 BR00118040 TUBB3 final orf G06 U2OS 96 5016 Binuclear +0.10323258662241713 1.7097927343303611e-09 BR00118039 DYRK1B final orf M12 U2OS 96 1950 Binuclear +0.07209322647734488 2.581876047535094e-09 BR00118040 SLC29A1 final orf N03 U2OS 96 3930 Binuclear +0.06381359219156181 3.094876908910017e-09 BR00118039 CTSG final orf J12 U2OS 96 4974 Binuclear +0.07017543859649122 3.2927860080894762e-09 BR00118039 CACNB4 final orf M01 U2OS 96 4104 Binuclear +0.07734998340452863 3.797152813392241e-09 BR00118040 DYRK1B final orf G13 U2OS 96 3336 Binuclear +0.058670312663010524 5.24393507030512e-09 BR00118039 CCND1 final orf P16 U2OS 96 5718 Binuclear +0.0940791665404767 5.268921843530103e-09 BR00118040 HSD11B1 final orf G23 U2OS 96 2226 Binuclear +0.07628782075833014 6.018255932329678e-09 BR00118040 SLC7A11 final orf A03 U2OS 96 3360 Binuclear +0.061502956833069555 7.629961216083396e-09 BR00118040 RNASE1 final orf I18 U2OS 96 5106 Binuclear +0.05230354711435247 7.679230416093114e-09 BR00118039 TUBB4B final orf E04 U2OS 96 7068 Binuclear +0.06874468483791459 7.739811280504929e-09 BR00118039 LYN final orf C20 U2OS 96 4080 Binuclear +0.06414955164232673 8.40908883990771e-09 BR00118040 UGT1A9 final orf E24 U2OS 96 4668 Binuclear +0.06448268304607552 8.439411655936402e-09 BR00118040 CDC25A final orf M04 U2OS 96 4620 Binuclear +0.06233236455055685 9.90504389645117e-09 BR00118040 F10 final orf I04 U2OS 96 4896 Binuclear +0.06706483729982425 1.0884939445708267e-08 BR00118040 PPAT final orf H14 U2OS 96 4212 Binuclear +0.059250947391190405 1.1811264455925379e-08 BR00118040 S1PR1 final orf L01 U2OS 96 5370 Binuclear +0.06411127932056371 1.5128851726776273e-08 BR00118040 IMPDH1 final orf N20 U2OS 96 4530 Binuclear +0.06452780553768228 1.713120126929288e-08 BR00118039 LCK final orf H01 U2OS 96 4452 Binuclear +0.056066491398296496 1.907244417905678e-08 BR00118039 BAX final orf G12 U2OS 96 5844 Binuclear +0.05915529899730377 2.4668743325668586e-08 BR00118040 GHSR final orf A17 U2OS 96 5196 Binuclear +0.053451114689406484 2.7873323523647274e-08 BR00118039 FFAR4 final orf C17 U2OS 96 6300 Binuclear +0.0631367232714776 2.888191220911321e-08 BR00118040 SIRT2 final orf G02 U2OS 96 4518 Binuclear +0.05620360551431601 3.432338304916495e-08 BR00118040 ITGB2 final orf B12 U2OS 96 5658 Binuclear +0.055560843996404506 3.637873615962039e-08 BR00118039 AVPR1A final orf H22 U2OS 96 5748 Binuclear +0.05491602607621045 4.094679558292307e-08 BR00118039 DCK final orf D05 U2OS 96 5838 Binuclear +0.06283007622006286 4.123907588333568e-08 BR00118039 AKR1C1 final orf A24 U2OS 96 4464 Binuclear +0.07001133786848072 6.106350274649727e-08 BR00118040 IMPDH1 final orf L13 U2OS 96 3528 Binuclear +0.05013240094976728 6.357616334795295e-08 BR00118039 HCK final orf O20 U2OS 96 6834 Binuclear +0.06648488051765007 6.749988310480214e-08 BR00118040 CATSPER4 final orf P07 U2OS 96 3870 Binuclear +0.05220306513409962 7.667788679887595e-08 BR00118040 ERBB2 final orf E21 U2OS 96 6264 Binuclear +0.06058278121042038 8.337371719343778e-08 BR00118040 HIF1A final orf A12 U2OS 96 4614 Binuclear +0.06505869784427956 8.525164835767083e-08 BR00118040 CHRM3 final orf A10 U2OS 96 4002 Binuclear +0.059283183996665975 8.737189270390427e-08 BR00118039 PLK1 final orf L11 U2OS 96 4800 Binuclear +0.056473620900031454 9.443400430191902e-08 BR00118039 GPR55 final orf H16 U2OS 96 5268 Binuclear +0.04928550597841937 1.1585938971951575e-07 BR00118039 PAK4 final orf G10 U2OS 96 6858 Binuclear +0.05205787828251642 1.268035920541265e-07 BR00118039 ATP5F1D final orf G14 U2OS 96 6084 Binuclear +0.05949367785404843 1.2715389443778592e-07 BR00118039 NTRK1 final orf P02 U2OS 96 4668 Binuclear +0.05514029872723424 1.3142881455593487e-07 BR00118039 MMP2 final orf F06 U2OS 96 5418 Binuclear +0.07673090649536046 1.3509711008822934e-07 BR00118040 PDPK1 final orf H15 U2OS 96 2802 Binuclear +0.06296727719346129 1.3684543458604266e-07 BR00118040 CACNB4 final orf M01 U2OS 96 4152 Binuclear +0.06040268456375839 1.63953705527132e-07 BR00118039 LPAR1 final orf B20 U2OS 96 4470 Binuclear +0.05645299575351081 1.8719192237549318e-07 BR00118040 CATSPER4 final orf D24 U2OS 96 5058 Binuclear +0.05312170474801131 1.9693166034340806e-07 BR00118039 TBXAS1 final orf P23 U2OS 96 5694 Binuclear +0.05805871107423361 2.217226618954309e-07 BR00118039 CCR1 final orf F24 U2OS 96 4728 Binuclear +0.06478640357243197 2.6073443232175136e-07 BR00118039 KRAS final orf F08 U2OS 96 3762 Binuclear +0.054913943551175834 3.187320568185386e-07 BR00118039 TNF final orf C13 U2OS 96 5166 Binuclear +0.05270824428757897 3.2923982121659817e-07 BR00118040 PTPN2 final orf O15 U2OS 96 5592 Binuclear +0.06047819971870605 3.320693097703323e-07 BR00118039 MAPK8 final orf I13 U2OS 96 4266 Binuclear +0.07984218979697451 3.642142399411206e-07 BR00118040 LYN final orf M05 U2OS 96 2412 Binuclear +0.05975373744773952 3.7780284403910476e-07 BR00118040 BTK final orf N01 U2OS 96 4314 Binuclear +0.05353522473838541 5.314576323578556e-07 BR00118039 CSK final orf P05 U2OS 96 5274 Binuclear +0.057683839718185824 5.426805702462314e-07 BR00118040 PLA2G1B final orf E06 U2OS 96 4542 Binuclear +0.04902897166507482 5.50395542984078e-07 BR00118040 TGM2 final orf B07 U2OS 96 6282 Binuclear +0.04863226942072832 5.595409970817817e-07 BR00118040 PAK4 final orf M19 U2OS 96 6354 Binuclear +0.06269592476489028 5.791067785050391e-07 BR00118039 ABL1 final orf C01 U2OS 96 3828 Binuclear +0.04655368498895125 5.950479994716581e-07 BR00118039 KCNH7 final orf A22 U2OS 96 6924 Binuclear +0.058764666520400154 6.290038092985782e-07 BR00118040 CHRM3 final orf A11 U2OS 96 4314 Binuclear +0.05385738540974601 6.33149738742487e-07 BR00118040 MME final orf I11 U2OS 96 5148 Binuclear +0.05231390147231761 6.958679469326998e-07 BR00118039 KDR final orf O02 U2OS 96 5406 Binuclear +0.06191950464396285 6.979460474470048e-07 BR00118040 OPRM1 final orf A09 U2OS 96 3876 Binuclear +0.054740996873475764 7.063280612059179e-07 BR00118040 GUCY1B1 final orf J08 U2OS 96 4926 Binuclear +0.046338781611126346 7.101259070338344e-07 BR00118040 ADORA2A final orf O23 U2OS 96 6888 Binuclear 0.7516038492381716 2.1732472598153855e-48 BR00118040 GRIN2A final orf A05 U2OS 96 174 Elongated 0.1833822149922225 3.652411111605564e-47 BR00118040 LYN final orf C20 U2OS 96 3180 Elongated 0.15981399902104748 6.157219511736582e-46 BR00118039 LYN final orf M05 U2OS 96 4086 Elongated @@ -1699,6 +16909,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.19154563073810682 9.811329261819347e-29 BR00118040 KRAS final orf D17 U2OS 96 1764 Elongated 0.10615724930845265 9.501537221830218e-26 BR00118039 CA5A final orf B23 U2OS 96 5160 Elongated 0.09048568669827123 4.2170155882938995e-25 BR00118039 KCNH7 final orf A22 U2OS 96 6924 Elongated +0.1083223249669749 1.2958997928872032e-23 BR00118040 PLA2G1B final orf E06 U2OS 96 4542 Elongated +0.1556573019205846 5.923394887065764e-23 BR00118040 PTK2B final orf J18 U2OS 96 2124 Elongated +0.1225518232508418 1.0404987158837261e-22 BR00118040 LPAR1 final orf B20 U2OS 96 3396 Elongated +0.11359671306096197 8.978336310924016e-22 BR00118040 KRAS final orf F08 U2OS 96 3798 Elongated +0.08173049492451351 1.0721596202920874e-21 BR00118040 P3H1 final orf F23 U2OS 96 7308 Elongated +0.09831691297208539 6.56875569054512e-21 BR00118039 MAPK14 final orf G15 U2OS 96 4872 Elongated +0.08992617558974768 9.101614630555194e-19 BR00118039 KCNMA1 final orf O08 U2OS 96 5202 Elongated +0.1207983193277311 1.4472354877745764e-18 BR00118040 CDK9 final orf H11 U2OS 96 2856 Elongated +0.08463576684020542 1.5310673311656294e-18 BR00118040 CCR1 final orf F24 U2OS 96 5796 Elongated +0.086764212568451 7.876918867512962e-18 BR00118039 RPL3 final orf G09 U2OS 96 5298 Elongated +0.07584342720320278 1.0890228148294279e-17 BR00118040 ADORA2A final orf O23 U2OS 96 6888 Elongated +0.07906274280102221 2.3384640303141854e-17 BR00118040 HTR2C final orf G21 U2OS 96 6228 Elongated +0.08670605216575515 4.5952438498522827e-17 BR00118040 TBXAS1 final orf P23 U2OS 96 5070 Elongated +0.07636607072090944 5.567419535095862e-17 BR00118039 EDNRB final orf K11 U2OS 96 6510 Elongated +0.095900439238653 8.124277614637637e-17 BR00118040 COMT final orf P09 U2OS 96 4098 Elongated +0.09207105805613036 4.078517550849533e-16 BR00118040 NTRK1 final orf P02 U2OS 96 4248 Elongated +0.09304433243229679 7.422483978128989e-16 BR00118039 P3H1 final orf P24 U2OS 96 4092 Elongated +0.08168573841600349 1.7978361716682865e-15 BR00118039 ABL1 final orf M24 U2OS 96 5172 Elongated +0.08470287379960299 2.1902792835812553e-15 BR00118040 NAMPT final orf D13 U2OS 96 4776 Elongated +0.07342934252602454 3.067424790518016e-15 BR00118039 ADORA2A final orf O18 U2OS 96 6300 Elongated +0.07599043715846994 4.000638652113886e-15 BR00118039 IL1B final orf G08 U2OS 96 5856 Elongated +0.07346807828039782 4.739417671742366e-15 BR00118040 P3H1 final orf P24 U2OS 96 6234 Elongated +0.10309930423782417 4.792705155230833e-15 BR00118040 ABL1 final orf C01 U2OS 96 3162 Elongated +0.07436706840747631 8.268103033990858e-15 BR00118039 TUBB3 final orf G06 U2OS 96 5976 Elongated +0.08921624139253685 9.445398776482684e-15 BR00118040 CCR1 final orf P17 U2OS 96 4134 Elongated +0.09237921355228994 2.0025946305664127e-14 BR00118039 KRAS final orf F08 U2OS 96 3762 Elongated +0.07271257793488108 4.513172950930015e-14 BR00118040 PAK4 final orf G10 U2OS 96 5928 Elongated +0.0777250119803006 4.930702072333872e-14 BR00118039 EDNRB final orf M08 U2OS 96 5178 Elongated +0.0726564825458498 6.979771578439823e-14 BR00118039 BAX final orf G12 U2OS 96 5844 Elongated +0.07505643340857787 1.9229863398969526e-13 BR00118040 CACNB4 final orf A18 U2OS 96 5316 Elongated +0.0745859724240441 2.6716735896567984e-13 BR00118039 PLA2G1B final orf E06 U2OS 96 5304 Elongated +0.0843723846750487 2.727416635167079e-13 BR00118040 ABL1 final orf M24 U2OS 96 4152 Elongated +0.08051296739009721 3.2734786344841916e-13 BR00118040 IMPDH1 final orf N20 U2OS 96 4530 Elongated +0.07123227346802283 3.3805489889538017e-13 BR00118039 BRD4 final orf F14 U2OS 96 5778 Elongated +0.0773640101201771 3.4898441026302243e-13 BR00118040 HPGDS final orf O24 U2OS 96 4896 Elongated +0.06617246251579575 3.494370459637048e-13 BR00118039 TBXAS1 final orf J24 U2OS 96 6684 Elongated +0.09180977740695016 3.7935482605296063e-13 BR00118040 NTRK1 final orf D01 U2OS 96 3468 Elongated +0.06279555627752509 5.989129330667393e-13 BR00118040 MAPK14 final orf G22 U2OS 96 7296 Elongated +0.07078428095630789 6.033544401241932e-13 BR00118040 GRIN2A final orf I24 U2OS 96 5730 Elongated +0.09712972925814989 8.112892851402202e-13 BR00118039 DYRK1B final orf G13 U2OS 96 3012 Elongated +0.07944962272525521 8.64477753202834e-13 BR00118040 MAPK8 final orf I14 U2OS 96 4506 Elongated +0.09163394269605286 1.2476336748969909e-12 BR00118040 DYRK1B final orf G13 U2OS 96 3336 Elongated +0.06387128894412215 1.3121384621184626e-12 BR00118039 HSP90AA1 final orf C14 U2OS 96 6864 Elongated +0.07299361163421425 2.1412096601472905e-12 BR00118039 SLCO2B1 final orf O13 U2OS 96 5160 Elongated +0.07104174144050457 2.4039242219100415e-12 BR00118039 MMP2 final orf F06 U2OS 96 5418 Elongated +0.08386075949367089 5.096885081818905e-12 BR00118039 DNMT3A final orf H07 U2OS 96 3792 Elongated +0.06887057277668279 6.126976923813975e-12 BR00118040 CDK2 final orf J04 U2OS 96 5580 Elongated +0.08575960951799878 6.383635032086228e-12 BR00118040 PAK1 final orf L09 U2OS 96 3576 Elongated +0.07047558491088034 7.171566136935385e-12 BR00118039 KCNJ1 final orf M03 U2OS 96 5298 Elongated +0.09010167067698772 7.482275309939463e-12 BR00118040 LPAR1 final orf B05 U2OS 96 3234 Elongated +0.07706760441377682 7.737397398516347e-12 BR00118039 GAA final orf N04 U2OS 96 4416 Elongated +0.08309083880877714 9.216772833904747e-12 BR00118040 SLCO2B1 final orf A02 U2OS 96 3762 Elongated +0.06748021224590642 9.268123748108475e-12 BR00118039 PPARD final orf M07 U2OS 96 5712 Elongated +0.07220641385262704 9.508712259702796e-12 BR00118039 LPAR1 final orf B05 U2OS 96 4992 Elongated +0.07950951535875572 1.1708586340652154e-11 BR00118040 FOXM1 final orf P15 U2OS 96 4080 Elongated +0.07772137928795893 1.693403156770862e-11 BR00118040 PPAT final orf H14 U2OS 96 4212 Elongated +0.06650648445712021 1.8297450055621274e-11 BR00118040 ICAM1 final orf I15 U2OS 96 5730 Elongated +0.07910869624873082 1.8780654784773116e-11 BR00118039 PNLIP final orf L22 U2OS 96 4050 Elongated +0.0663740278886258 3.012713674224224e-11 BR00118040 RPL3 final orf G09 U2OS 96 5628 Elongated +0.07828655834564253 3.0163249682760174e-11 BR00118039 CASP3 final orf J10 U2OS 96 4062 Elongated +0.07225765970243142 3.201914584448806e-11 BR00118040 FFAR2 final orf B15 U2OS 96 4752 Elongated +0.07404921700223714 4.4441676336665225e-11 BR00118039 LPAR1 final orf B20 U2OS 96 4470 Elongated +0.06617860831271069 4.994288699715774e-11 BR00118040 TBXAS1 final orf J24 U2OS 96 5550 Elongated +0.06883629191321498 7.250593865122864e-11 BR00118039 DHH final orf G05 U2OS 96 5070 Elongated +0.08099585436193223 7.299121615702878e-11 BR00118039 CA14 final orf J14 U2OS 96 3648 Elongated +0.0779733732321811 7.401573075263907e-11 BR00118040 CCND1 final orf B11 U2OS 96 3942 Elongated +0.06722112036121698 1.7923837207003773e-10 BR00118040 GABRB2 final orf C06 U2OS 96 5106 Elongated +0.44894894894894893 1.8515393121991907e-10 BR00118039 SCNN1G final orf A04 U2OS 96 108 Elongated +0.06427933634746687 1.9535432413366762e-10 BR00118040 HCK final orf O20 U2OS 96 5562 Elongated +0.08447402565292027 2.173741514890126e-10 BR00118039 PTK2B final orf J18 U2OS 96 3192 Elongated +0.08483577009136789 2.389428386364453e-10 BR00118040 PRKCE final orf J19 U2OS 96 3156 Elongated +0.08888013624121296 3.517895261250782e-10 BR00118040 BRD4 final orf N17 U2OS 96 2826 Elongated +0.06652661529972544 3.976978733596464e-10 BR00118039 F10 final orf C09 U2OS 96 5028 Elongated +0.05940208014356536 4.3435527654731023e-10 BR00118039 GPR55 final orf F13 U2OS 96 6288 Elongated +0.057622504537205084 5.779523869733712e-10 BR00118039 GABRB2 final orf C19 U2OS 96 6612 Elongated +0.053229974160206715 5.92570178381733e-10 BR00118039 ERBB2 final orf I20 U2OS 96 7740 Elongated +0.06426736557991215 7.058181838773113e-10 BR00118039 TNNC1 final orf M18 U2OS 96 5256 Elongated +0.06757795350644527 7.553182823522513e-10 BR00118039 CCR1 final orf F24 U2OS 96 4728 Elongated +0.06080407908373135 8.001938041550353e-10 BR00118039 SLC7A11 final orf G24 U2OS 96 5844 Elongated +0.06488405774898683 1.151033059438623e-09 BR00118040 CA5A final orf B02 U2OS 96 5046 Elongated +0.07141519792781124 1.3456445718409037e-09 BR00118039 IMPDH1 final orf L13 U2OS 96 4128 Elongated +0.06584509548463365 1.4686342763151575e-09 BR00118040 ATM final orf C04 U2OS 96 4824 Elongated +0.06313319473175036 1.5044233073771934e-09 BR00118039 TNNC1 final orf G07 U2OS 96 5256 Elongated +0.06763544636981794 1.6848872544210977e-09 BR00118039 HSD11B1 final orf C02 U2OS 96 4560 Elongated +0.06258641385433782 2.109218395991985e-09 BR00118040 TNF final orf C13 U2OS 96 5256 Elongated +0.05082831325301205 2.278156434947147e-09 BR00118039 HIF1A final orf C23 U2OS 96 7968 Elongated +0.05968025265240635 2.4132784302239298e-09 BR00118039 HBB final orf C10 U2OS 96 5754 Elongated +0.061188925511412216 2.6068275664149383e-09 BR00118040 KCNQ2 final orf K01 U2OS 96 5436 Elongated +0.060193815450408465 2.7398270686060634e-09 BR00118040 KCTD16 final orf M22 U2OS 96 5616 Elongated +0.078174149193207 2.771223007682258e-09 BR00118039 MAPK8 final orf I14 U2OS 96 3324 Elongated 0.19008235706878038 1.3923245831159474e-68 BR00118040 CHRM3 final orf A11 U2OS 96 4314 Grape 0.16724988134597904 1.8610210355115287e-46 BR00118040 SLCO2B1 final orf A02 U2OS 96 3762 Grape 0.1503674651714718 7.455299112233169e-41 BR00118039 P3H1 final orf P24 U2OS 96 4092 Grape @@ -1709,6 +17009,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.13163656267104543 5.32781403135255e-28 BR00118040 KCNN4 final orf A06 U2OS 96 3654 Grape 0.1179207083236058 5.7503713471251105e-28 BR00118039 CDK4 final orf P20 U2OS 96 4542 Grape 0.10768926419300846 1.1003294086475921e-26 BR00118040 GHSR final orf A17 U2OS 96 5196 Grape +0.1162962163941704 2.49598045141687e-26 BR00118040 SCNN1G final orf A04 U2OS 96 4386 Grape +0.11333840403693435 2.798584304457578e-26 BR00118040 HIF1A final orf A12 U2OS 96 4614 Grape +0.1124714905135467 2.8036741736348744e-26 BR00118040 KCNH7 final orf A22 U2OS 96 4692 Grape +0.12400327195299378 6.458517681080943e-26 BR00118040 KRAS final orf F08 U2OS 96 3798 Grape +0.1028969149736644 6.545247950427829e-25 BR00118040 CACNB4 final orf A18 U2OS 96 5316 Grape +0.12329717149176186 1.275962687850752e-24 BR00118039 KCNN1 final orf A01 U2OS 96 3642 Grape +0.12034792599391816 2.009605698531281e-24 BR00118040 OPRL1 final orf A23 U2OS 96 3798 Grape +0.12487181775807524 4.5150381071679306e-24 BR00118040 OPRM1 final orf A08 U2OS 96 3480 Grape +0.10989733046156455 5.596895604537265e-23 BR00118039 ADA final orf P03 U2OS 96 4290 Grape +0.08949322021059011 6.480670429743808e-23 BR00118039 AKT1 final orf F15 U2OS 96 6450 Grape +0.08896483946809396 4.0650728792078215e-22 BR00118039 FFAR4 final orf C17 U2OS 96 6300 Grape +0.12119974481768689 8.027874306040067e-22 BR00118040 DYRK1B final orf G13 U2OS 96 3336 Grape +0.11057505488695292 9.6984695484886e-22 BR00118040 CHRM3 final orf A10 U2OS 96 4002 Grape +0.10709585962293368 3.1826613518681948e-21 BR00118040 CACNB4 final orf M01 U2OS 96 4152 Grape +0.11102693838471547 1.2074548083800097e-20 BR00118039 KRAS final orf F08 U2OS 96 3762 Grape +0.10668535918878114 4.2413533002615866e-20 BR00118039 HSP90AB1 final orf P01 U2OS 96 3966 Grape +0.10711661699682502 4.987459504104302e-20 BR00118040 DDR2 final orf A19 U2OS 96 3924 Grape +0.08184872487380851 5.971008623985723e-20 BR00118039 TBXAS1 final orf J24 U2OS 96 6684 Grape +0.15 2.974763734724712e-19 BR00118039 SLCO2B1 final orf A02 U2OS 96 1920 Grape +0.48616680032076987 3.2527522947440067e-19 BR00118040 GRIN2A final orf A05 U2OS 96 174 Grape +0.11311864334652538 3.4870307796047795e-19 BR00118040 SLC7A11 final orf A03 U2OS 96 3360 Grape +0.10534507335511564 3.8993483562353386e-19 BR00118040 CYP2A6 final orf A15 U2OS 96 3870 Grape +0.07864286302584182 4.579128730242608e-19 BR00118039 KCNH7 final orf A22 U2OS 96 6924 Grape +0.10230053842388644 5.007808947921921e-19 BR00118039 SIRT2 final orf A07 U2OS 96 4086 Grape +0.09013217645007267 7.136865744681576e-19 BR00118040 ADA final orf P04 U2OS 96 5208 Grape +0.10133394885131584 8.886429689501496e-19 BR00118040 SIRT2 final orf A07 U2OS 96 4092 Grape +0.08746715886169895 2.6884183113481848e-18 BR00118040 GHSR final orf C24 U2OS 96 5364 Grape +0.0969738651994498 2.886149356471681e-18 BR00118040 CYP1A2 final orf N12 U2OS 96 4362 Grape +0.12996868125184274 2.961488464781073e-18 BR00118040 LYN final orf M05 U2OS 96 2412 Grape +0.09485693856556653 3.764350842981678e-18 BR00118040 SIRT2 final orf G02 U2OS 96 4518 Grape +0.0907792000650841 2.065302019689179e-17 BR00118039 CYP2A6 final orf A20 U2OS 96 4734 Grape +0.09602726794658482 7.339114797187708e-17 BR00118040 AURKB final orf H10 U2OS 96 4086 Grape +0.08252163218676503 7.37573251704113e-17 BR00118039 SSTR2 final orf J01 U2OS 96 5532 Grape +0.09415331985694293 7.68135652477901e-17 BR00118040 P2RY12 final orf B01 U2OS 96 4248 Grape +0.10808035945340551 1.6761942699595092e-16 BR00118040 PRKCE final orf J19 U2OS 96 3156 Grape +0.07546375020431104 1.7300736440074239e-16 BR00118039 KCNJ1 final orf E22 U2OS 96 6468 Grape +0.09463164956932 2.3592033347139206e-16 BR00118040 FOXM1 final orf P15 U2OS 96 4080 Grape +0.07816151889152877 2.528176686047534e-16 BR00118040 P2RY12 final orf B24 U2OS 96 5970 Grape +0.073502722323049 5.945642199125383e-16 BR00118039 GABRB2 final orf C19 U2OS 96 6612 Grape +0.07864583333333333 6.515806344693299e-16 BR00118039 SIRT2 final orf G02 U2OS 96 5760 Grape +0.08883831911979144 9.195858557344127e-16 BR00118039 LCK final orf H01 U2OS 96 4452 Grape +0.07326017528223411 1.0810501978266058e-15 BR00118039 HDAC6 final orf E20 U2OS 96 6534 Grape +0.07886129650573175 1.1510872346221757e-15 BR00118039 ANXA1 final orf D23 U2OS 96 5628 Grape +0.07874713943622337 1.2731587021108806e-15 BR00118039 AKT1 final orf J16 U2OS 96 5628 Grape +0.06908464455634267 5.920018926978433e-15 BR00118039 PIK3CG final orf G18 U2OS 96 6996 Grape +0.07491533257870009 1.119316592436941e-14 BR00118039 DCK final orf D05 U2OS 96 5838 Grape +0.08880320567334996 1.9853060540304324e-14 BR00118039 LYN final orf C20 U2OS 96 4080 Grape +0.07296277053999486 2.0262645496880134e-14 BR00118039 CDC25A final orf M04 U2OS 96 6042 Grape +0.07943177270908364 3.915114817865596e-14 BR00118039 SLC7A11 final orf A03 U2OS 96 4998 Grape +0.06722076407115778 6.817211255246937e-14 BR00118039 CDK7 final orf M21 U2OS 96 6858 Grape +0.08233367797130024 9.019744917128942e-14 BR00118039 GRIN2A final orf A05 U2OS 96 4524 Grape +0.10201171912687573 1.299553920871246e-13 BR00118040 GJB4 final orf P08 U2OS 96 2898 Grape +0.07982120051085569 1.9447465663468358e-13 BR00118040 CACNG1 final orf A16 U2OS 96 4698 Grape +0.0636598891776767 2.6882495865479205e-13 BR00118040 MAPK14 final orf G22 U2OS 96 7296 Grape +0.0757434546520044 2.7254158110721827e-13 BR00118039 DDR2 final orf M02 U2OS 96 5154 Grape +0.0753708073704197 3.155603260728775e-13 BR00118039 EDNRB final orf M08 U2OS 96 5178 Grape +0.07369705112792589 4.030447866428465e-13 BR00118040 S1PR1 final orf L01 U2OS 96 5370 Grape +0.09019607843137255 4.702959935841106e-13 BR00118039 AKR1B1 final orf L17 U2OS 96 3570 Grape +0.07861149715624925 5.701387500860585e-13 BR00118039 CHRM3 final orf A11 U2OS 96 4662 Grape +0.07839681167876783 6.156071366842383e-13 BR00118040 UGT1A9 final orf E24 U2OS 96 4668 Grape +0.07782667179312242 1.5533961916626863e-12 BR00118040 MET final orf C03 U2OS 96 4584 Grape +0.08163759689922481 2.1924067184266486e-12 BR00118040 AKR1C1 final orf A24 U2OS 96 4128 Grape +0.07208454567480278 3.408428704848269e-12 BR00118040 CASP3 final orf N05 U2OS 96 5196 Grape +0.08065268491029692 3.696558873305206e-12 BR00118040 CCR1 final orf P17 U2OS 96 4134 Grape +0.07648848326814428 3.96236527843823e-12 BR00118039 AKR1C1 final orf I01 U2OS 96 4602 Grape +0.06973655260544918 5.837227004476124e-12 BR00118039 GPR119 final orf N23 U2OS 96 5436 Grape +0.11594958713602782 7.005881771493853e-12 BR00118039 DYRK1B final orf M12 U2OS 96 1950 Grape +0.06425270672183292 7.980468740606072e-12 BR00118039 HPGDS final orf O21 U2OS 96 6330 Grape +0.06571146245059288 8.073255701761008e-12 BR00118040 CLK1 final orf D08 U2OS 96 6072 Grape +0.06700828943396524 9.45195105829524e-12 BR00118040 EDNRB final orf K11 U2OS 96 5784 Grape +0.07764706578729293 1.12408962297399e-11 BR00118040 HTR2C final orf M06 U2OS 96 4272 Grape +0.06062717006758015 1.1309313554808064e-11 BR00118039 CHRM2 final orf B08 U2OS 96 7020 Grape +0.07442063653637351 1.4857417933766165e-11 BR00118040 TUBB3 final orf K05 U2OS 96 4608 Grape +0.06558110078279893 1.605220650040712e-11 BR00118040 PAK4 final orf G10 U2OS 96 5928 Grape +0.06768690049628583 1.629093653603554e-11 BR00118040 DHH final orf G05 U2OS 96 5556 Grape +0.06074436745363263 1.6764961092019174e-11 BR00118040 ADORA2A final orf O23 U2OS 96 6888 Grape +0.07881893606637384 1.715589796248014e-11 BR00118040 COMT final orf P09 U2OS 96 4098 Grape +0.07412872311053542 1.7715348667134784e-11 BR00118040 MMP2 final orf F06 U2OS 96 4614 Grape +0.06897117414686457 1.8232148523269354e-11 BR00118039 HTR2C final orf M06 U2OS 96 5322 Grape +0.07291009187180027 1.94283531893597e-11 BR00118040 AGER final orf H18 U2OS 96 4752 Grape +0.06320179659929419 3.020649522709612e-11 BR00118040 P3H1 final orf P24 U2OS 96 6234 Grape +0.07354221061792864 3.1410972906445495e-11 BR00118040 KDR final orf O02 U2OS 96 4596 Grape +0.06333432257882167 3.156281467414176e-11 BR00118040 PTGIS final orf F16 U2OS 96 6180 Grape +0.06512431323842063 3.591599025723789e-11 BR00118039 PARP3 final orf H21 U2OS 96 5826 Grape +0.0650958519529043 4.225839163957893e-11 BR00118039 BRD4 final orf F14 U2OS 96 5778 Grape +0.07569405404112292 4.7659984525121696e-11 BR00118040 NTRK1 final orf P02 U2OS 96 4248 Grape +0.06691292055921151 5.957835478745238e-11 BR00118039 HTR2C final orf G21 U2OS 96 5394 Grape +0.0701831573377287 6.06229172849327e-11 BR00118039 TGFBR1 final orf O14 U2OS 96 4908 Grape +0.06002458595421461 6.53513185948752e-11 BR00118039 KCTD16 final orf K21 U2OS 96 6678 Grape +0.06811088184676932 7.372096424993822e-11 BR00118039 CA5A final orf B23 U2OS 96 5160 Grape 0.6706094627105053 1.7212221616567327e-37 BR00118040 GRIN2A final orf A05 U2OS 96 174 Hole 0.09574385028028441 1.2480793086030055e-23 BR00118039 TUBB final orf E19 U2OS 96 5814 Hole 0.11238847168369921 6.109227728431533e-23 BR00118039 LYN final orf C20 U2OS 96 4080 Hole @@ -1719,6 +17109,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.12899584516022872 5.224243000078564e-20 BR00118040 DYRK1B final orf M12 U2OS 96 2700 Hole 0.10401370533529124 1.175650139110238e-19 BR00118039 LYN final orf M05 U2OS 96 4086 Hole 0.11382445870744985 2.918432461663089e-19 BR00118040 DYRK1B final orf G13 U2OS 96 3336 Hole +0.08692118458395133 1.0851382648509827e-18 BR00118040 DHH final orf G05 U2OS 96 5556 Hole +0.08917950507571902 2.093692921034977e-18 BR00118040 GHSR final orf A17 U2OS 96 5196 Hole +0.07747166882826952 5.180194871011474e-18 BR00118040 USP1 final orf G11 U2OS 96 6720 Hole +0.09991945001217616 6.10967192530717e-17 BR00118040 KRAS final orf F08 U2OS 96 3798 Hole +0.10802672156283588 6.838264745346387e-17 BR00118040 CCND1 final orf P16 U2OS 96 3228 Hole +0.09551727830248874 1.579351580738013e-16 BR00118040 SSTR2 final orf J01 U2OS 96 4044 Hole +0.12371317882201095 1.586331686805954e-16 BR00118040 LYN final orf M05 U2OS 96 2412 Hole +0.5540540540540541 3.9613938291943175e-16 BR00118039 SCNN1G final orf A04 U2OS 96 108 Hole +0.13707907962608776 4.519245742658506e-16 BR00118040 CLK1 final orf J17 U2OS 96 1902 Hole +0.08501166235832663 6.155046813550336e-16 BR00118040 EDNRB final orf M08 U2OS 96 4932 Hole +0.09718427376196066 6.447480358049294e-16 BR00118039 KRAS final orf F08 U2OS 96 3762 Hole +0.07795138888888889 1.2205052061892175e-15 BR00118039 SIRT2 final orf G02 U2OS 96 5760 Hole +0.0885614752685553 3.6064796777994065e-15 BR00118040 CHRM3 final orf A11 U2OS 96 4314 Hole +0.08510243580324117 1.1434928920374188e-14 BR00118040 SIRT2 final orf G02 U2OS 96 4518 Hole +0.08393537362878783 1.3999643897346672e-14 BR00118040 HIF1A final orf A12 U2OS 96 4614 Hole +0.0648578811369509 1.4189606968802162e-14 BR00118039 ERBB2 final orf I20 U2OS 96 7740 Hole +0.07653000388026762 1.9629192477622037e-14 BR00118040 LCK final orf B18 U2OS 96 5484 Hole +0.10229949478793518 3.307622298389583e-14 BR00118039 DYRK1B final orf G13 U2OS 96 3012 Hole +0.09454855195911414 4.063653169769826e-14 BR00118040 JAK1 final orf H17 U2OS 96 3522 Hole +0.07099940488247607 5.261349864453171e-14 BR00118040 PTGIS final orf F16 U2OS 96 6180 Hole +0.09885450105137474 7.039754563960603e-14 BR00118040 PRKCE final orf J19 U2OS 96 3156 Hole +0.06867862623696883 2.172720489677164e-13 BR00118039 FFAR4 final orf C17 U2OS 96 6300 Hole +0.08184319119669876 3.972469878006715e-13 BR00118040 CYP1A2 final orf N12 U2OS 96 4362 Hole +0.08421656425442213 4.4889788960713747e-13 BR00118039 P3H1 final orf P24 U2OS 96 4092 Hole +0.06559786382400414 8.676679180853617e-13 BR00118040 MAPK14 final orf G15 U2OS 96 6606 Hole +0.062335300700310445 9.129009497716214e-13 BR00118040 MAPK14 final orf G22 U2OS 96 7296 Hole +0.07167909168835403 1.6313289152100419e-12 BR00118039 HTR2C final orf G21 U2OS 96 5394 Hole +0.07899947578733917 2.5280983860989656e-12 BR00118039 VEGFA final orf P18 U2OS 96 4374 Hole +0.06877148030240625 5.131624732170225e-12 BR00118039 AKT1 final orf J16 U2OS 96 5628 Hole +0.06250003251112271 5.454533395970091e-12 BR00118039 S1PR4 final orf K18 U2OS 96 6792 Hole +0.06707331122526682 1.59426319197328e-11 BR00118039 DDR2 final orf A19 U2OS 96 5658 Hole +0.06628908038130726 2.1104880379093853e-11 BR00118039 ATM final orf C04 U2OS 96 5736 Hole +0.0654094461433911 2.2775548239547547e-11 BR00118040 DCK final orf L18 U2OS 96 5886 Hole +0.07787813476045224 2.426257015447182e-11 BR00118040 CCR1 final orf P17 U2OS 96 4134 Hole +0.07116489515472997 7.582006312558866e-11 BR00118039 EZH2 final orf D04 U2OS 96 4722 Hole +0.07637158719622059 7.84124814822179e-11 BR00118040 AURKB final orf H10 U2OS 96 4086 Hole +0.11566556247924822 1.0059224280517121e-10 BR00118039 KCNMA1 final orf G01 U2OS 96 1764 Hole +0.06408475593217552 1.1263162039499135e-10 BR00118040 KCNQ2 final orf K02 U2OS 96 5730 Hole +0.06111645813282002 1.5234551263691746e-10 BR00118040 P3H1 final orf P24 U2OS 96 6234 Hole +0.06039476255033346 1.8125103108938284e-10 BR00118039 HPGDS final orf O21 U2OS 96 6330 Hole +0.062 1.9005144333030474e-10 BR00118040 PRKCB final orf K14 U2OS 96 6000 Hole +0.07062146892655367 2.1178552092591687e-10 BR00118039 AKR1C1 final orf I01 U2OS 96 4602 Hole +0.06102664786533093 3.0240516914792806e-10 BR00118040 S1PR4 final orf K18 U2OS 96 6054 Hole +0.06188190576062689 3.41531336737451e-10 BR00118039 RET final orf K10 U2OS 96 5844 Hole +0.06388248017303533 3.641443138614846e-10 BR00118040 HSP90AA1 final orf C14 U2OS 96 5472 Hole +0.05679208105200784 3.8338118249676983e-10 BR00118039 KCNH7 final orf A22 U2OS 96 6924 Hole +0.06116207951070336 5.412845899644547e-10 BR00118040 CYP3A4 final orf K22 U2OS 96 5886 Hole +0.05905762496020376 6.035216877599926e-10 BR00118040 TGM2 final orf B07 U2OS 96 6282 Hole +0.07262432299359921 9.76294402267247e-10 BR00118039 CASP3 final orf J10 U2OS 96 4062 Hole +0.0623868239628476 1.5333989711581714e-09 BR00118039 CACNA2D3 final orf P19 U2OS 96 5364 Hole +0.061929978209909635 2.810201498852566e-09 BR00118040 HRH4 final orf O05 U2OS 96 5298 Hole +0.056214204351641144 3.64406659626425e-09 BR00118040 RET final orf K10 U2OS 96 6342 Hole +0.059698600234772005 3.691064849201809e-09 BR00118039 PDE3A final orf O22 U2OS 96 5634 Hole +0.06874327488862454 5.13283084271694e-09 BR00118040 GAA final orf N04 U2OS 96 4164 Hole +0.06195969890279918 6.6782846341344195e-09 BR00118040 TBXAS1 final orf P23 U2OS 96 5070 Hole +0.058604295188184705 7.618622092091211e-09 BR00118039 ANXA1 final orf D23 U2OS 96 5628 Hole +0.06502441189525078 1.0516337663189343e-08 BR00118040 MAPK8 final orf I14 U2OS 96 4506 Hole +0.05898548164033703 1.1022022527584561e-08 BR00118040 PIK3CG final orf G18 U2OS 96 5436 Hole +0.06239737274220033 1.1441349237601933e-08 BR00118039 MAPK14 final orf G15 U2OS 96 4872 Hole +0.05771538781247519 1.185150723947124e-08 BR00118040 TGFBR1 final orf I23 U2OS 96 5670 Hole +0.056510682554681106 2.001549267854602e-08 BR00118039 HBB final orf C10 U2OS 96 5754 Hole +0.05600376167484496 2.1190883083379247e-08 BR00118039 KCNN1 final orf O10 U2OS 96 5844 Hole +0.06713408076133363 2.3851213219545975e-08 BR00118039 DCK final orf L18 U2OS 96 4026 Hole +0.06778610419041442 2.7346189998834866e-08 BR00118040 SLC29A1 final orf N03 U2OS 96 3930 Hole +0.08546496070405644 2.9641582381189143e-08 BR00118040 PORCN final orf N11 U2OS 96 2460 Hole +0.06428497382470326 4.435613775202481e-08 BR00118040 NTRK1 final orf P02 U2OS 96 4248 Hole +0.06205894972907484 4.7692761097139905e-08 BR00118039 CDK4 final orf P20 U2OS 96 4542 Hole +0.06230319388214125 6.338266468216785e-08 BR00118040 CDC25A final orf I19 U2OS 96 4446 Hole +0.062135486765365636 6.640185186316144e-08 BR00118040 CDK7 final orf K06 U2OS 96 4458 Hole +0.07097918750792921 6.676081127609109e-08 BR00118040 LPAR1 final orf B20 U2OS 96 3396 Hole +0.08928177001418416 7.635822176185618e-08 BR00118040 PTK2B final orf J18 U2OS 96 2124 Hole +0.04894328738164076 9.511740779588841e-08 BR00118040 HBB final orf C10 U2OS 96 7014 Hole +0.04982180029182972 1.0079750203568013e-07 BR00118039 DHH final orf E08 U2OS 96 6744 Hole +0.05145214997535673 1.0112910661963957e-07 BR00118039 RGS4 final orf D09 U2OS 96 6318 Hole +0.0544361965358784 1.0388222409613928e-07 BR00118040 ITGB2 final orf B12 U2OS 96 5658 Hole +0.06215060283753246 1.288013585916535e-07 BR00118040 HTR2C final orf M06 U2OS 96 4272 Hole +0.0499092558983666 1.3987666511725313e-07 BR00118039 GABRB2 final orf C19 U2OS 96 6612 Hole +0.06056730282077621 1.4499315382566027e-07 BR00118039 LCK final orf H01 U2OS 96 4452 Hole +0.056157249308452645 1.6354222860449727e-07 BR00118039 SLCO2B1 final orf O13 U2OS 96 5160 Hole +0.0506066411238825 2.145484035983491e-07 BR00118040 ERBB2 final orf E21 U2OS 96 6264 Hole +0.05025298152772421 2.244806172803979e-07 BR00118040 ERBB2 final orf I20 U2OS 96 6318 Hole +0.05276714290874308 2.2818427324183972e-07 BR00118039 CCND1 final orf P16 U2OS 96 5718 Hole +0.05547811938453854 2.6647249573220294e-07 BR00118039 AURKB final orf H10 U2OS 96 5112 Hole +0.06094528527139452 2.673915250357611e-07 BR00118039 NAMPT final orf L06 U2OS 96 4236 Hole +0.05436418359668924 2.9853751864663916e-07 BR00118040 CACNB4 final orf A18 U2OS 96 5316 Hole +0.052987059105858984 3.610791156169207e-07 BR00118040 USP1 final orf E12 U2OS 96 5502 Hole +0.061429270680372 3.993524470213225e-07 BR00118039 SIRT2 final orf A07 U2OS 96 4086 Hole +0.053678678678678676 4.2767882364544233e-07 BR00118040 VEGFA final orf B09 U2OS 96 5328 Hole +0.06058429118773946 4.3748189620622194e-07 BR00118039 MMP2 final orf J15 U2OS 96 4176 Hole +0.056188425217599126 4.386490714383825e-07 BR00118039 GJB4 final orf P08 U2OS 96 4848 Hole 0.7752606255012029 2.3688310081056155e-52 BR00118040 GRIN2A final orf A05 U2OS 96 174 Interphase 0.12767294807248764 4.095607044220761e-31 BR00118040 CHRM3 final orf A11 U2OS 96 4314 Interphase 0.10210483101724675 2.537687212679604e-24 BR00118040 TNF final orf C13 U2OS 96 5256 Interphase @@ -1729,6 +17209,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.09542507010609401 9.731574272524406e-23 BR00118039 AKT1 final orf J16 U2OS 96 5628 Interphase 0.14951127149247814 3.6651708852447516e-21 BR00118040 PTK2B final orf J18 U2OS 96 2124 Interphase 0.10747549634685845 5.146610817641893e-21 BR00118039 P3H1 final orf P24 U2OS 96 4092 Interphase +0.09940249168477783 5.432221838057733e-20 BR00118039 CDK4 final orf P20 U2OS 96 4542 Interphase +0.0930497985047915 6.64342934100037e-20 BR00118039 DDR2 final orf M02 U2OS 96 5154 Interphase +0.0953433286546363 1.021578019094348e-18 BR00118040 HIF1A final orf A12 U2OS 96 4614 Interphase +0.10394070521826548 2.520743693334898e-18 BR00118040 OPRL1 final orf A23 U2OS 96 3798 Interphase +0.07721899000243893 2.7211514036654264e-18 BR00118040 ADORA2A final orf O23 U2OS 96 6888 Interphase +0.08723457223702841 1.2285775793493132e-17 BR00118040 GHSR final orf A17 U2OS 96 5196 Interphase +0.09513984410820725 1.348271979780691e-17 BR00118040 CYP1A2 final orf N12 U2OS 96 4362 Interphase +0.08717010713352495 1.6984614804626356e-17 BR00118039 CA5A final orf B23 U2OS 96 5160 Interphase +0.07732386796094091 3.152382188416351e-17 BR00118039 AKT1 final orf F15 U2OS 96 6450 Interphase +0.10890396203962155 4.060930884673852e-17 BR00118040 CCND1 final orf P16 U2OS 96 3228 Interphase +0.0821657833716006 5.679917164630355e-17 BR00118039 ANXA1 final orf D23 U2OS 96 5628 Interphase +0.09038188622530026 1.731657083226705e-16 BR00118040 SIRT2 final orf G02 U2OS 96 4518 Interphase +0.08288325735129043 5.273763194798159e-16 BR00118040 CASP3 final orf N05 U2OS 96 5196 Interphase +0.08293188228260706 6.456477555781531e-16 BR00118039 EDNRB final orf M08 U2OS 96 5178 Interphase +0.07590921572769979 1.1645712865399936e-15 BR00118039 TUBB final orf M16 U2OS 96 6078 Interphase +0.08984636254396106 1.7124541153669445e-15 BR00118039 ADA final orf P03 U2OS 96 4290 Interphase +0.07725694444444445 2.2734416903056866e-15 BR00118039 SIRT2 final orf G02 U2OS 96 5760 Interphase +0.09300763982317893 4.94663029476256e-15 BR00118040 CYP2A6 final orf A15 U2OS 96 3870 Interphase +0.07217604877642067 7.850991230759649e-15 BR00118040 PDE3A final orf O22 U2OS 96 6342 Interphase +0.07366666666666667 1.407589140549725e-14 BR00118040 PRKCB final orf K14 U2OS 96 6000 Interphase +0.07795776026828682 5.916671221469881e-14 BR00118040 PORCN final orf D22 U2OS 96 5112 Interphase +0.09369676320272573 7.159313263983869e-14 BR00118040 JAK1 final orf H17 U2OS 96 3522 Interphase +0.09168035030103995 8.823959518304193e-14 BR00118040 KCNN4 final orf A06 U2OS 96 3654 Interphase +0.06790683605565638 1.1223426356363762e-13 BR00118039 GABRB2 final orf C19 U2OS 96 6612 Interphase +0.07305107272677377 1.1499752676414196e-13 BR00118039 KCNK1 final orf C22 U2OS 96 5688 Interphase +0.07176579075824245 1.6259628920342346e-13 BR00118039 KCNN1 final orf O10 U2OS 96 5844 Interphase +0.0909227314446326 2.0969160612547878e-13 BR00118040 ELANE final orf D19 U2OS 96 3606 Interphase +0.06782711095104983 2.0987482201987853e-13 BR00118040 CACNG1 final orf E23 U2OS 96 6480 Interphase +0.06770394542529672 2.4453275005828215e-13 BR00118039 KCNJ1 final orf E22 U2OS 96 6468 Interphase +0.08018252933507171 2.7479055133420284e-13 BR00118039 AKR1C1 final orf I01 U2OS 96 4602 Interphase +0.0680194135123489 4.0685349069329826e-13 BR00118039 FFAR4 final orf C17 U2OS 96 6300 Interphase +0.0656171441643055 6.071720800380104e-13 BR00118039 KCTD16 final orf K21 U2OS 96 6678 Interphase +0.09484639818395628 8.138494150179065e-13 BR00118040 PRKCE final orf J19 U2OS 96 3156 Interphase +0.4924924924924925 1.12935957588375e-12 BR00118039 SCNN1G final orf A04 U2OS 96 108 Interphase +0.06655672344238574 1.2719649983016583e-12 BR00118039 HPGDS final orf O21 U2OS 96 6330 Interphase +0.06673052362707535 1.5102911479232547e-12 BR00118040 ERBB2 final orf E21 U2OS 96 6264 Interphase +0.08360405853381864 1.5803451218433817e-12 BR00118039 HSP90AB1 final orf P01 U2OS 96 3966 Interphase +0.07726731378771688 2.0156859585025357e-12 BR00118040 MMP2 final orf F06 U2OS 96 4614 Interphase +0.06733677221853786 3.241115124012336e-12 BR00118039 TUBB3 final orf G06 U2OS 96 5976 Interphase +0.07013638548425859 3.661559899363635e-12 BR00118040 HSP90AA1 final orf C14 U2OS 96 5472 Interphase +0.06524906217957475 6.9737136494364665e-12 BR00118040 PTGIS final orf F16 U2OS 96 6180 Interphase +0.07119972120042899 7.605482909142457e-12 BR00118039 TNF final orf C13 U2OS 96 5166 Interphase +0.06970715900184667 7.898533744094824e-12 BR00118040 IL1B final orf E15 U2OS 96 5388 Interphase +0.06679907265437399 9.119125497397411e-12 BR00118039 BAX final orf G12 U2OS 96 5844 Interphase +0.0689044227999315 1.0256391189169436e-11 BR00118040 GPR119 final orf N23 U2OS 96 5460 Interphase +0.06282916058985577 1.1767443129822983e-11 BR00118039 HDAC6 final orf E20 U2OS 96 6534 Interphase +0.06296667695155816 1.2589247078543381e-11 BR00118039 PDE7A final orf F20 U2OS 96 6480 Interphase +0.08391533463417104 1.3365293496204474e-11 BR00118039 KCNN1 final orf A01 U2OS 96 3642 Interphase +0.0643933168994796 1.9870681565926082e-11 BR00118039 ATP5F1D final orf G14 U2OS 96 6084 Interphase +0.07322264793529161 2.254939991163389e-11 BR00118040 TNF final orf C18 U2OS 96 4698 Interphase +0.07839484829358873 2.8962168546145205e-11 BR00118039 PNLIP final orf L22 U2OS 96 4050 Interphase +0.06567248848968073 3.549138980050737e-11 BR00118039 CCND1 final orf P16 U2OS 96 5718 Interphase +0.06780652314632733 4.306828222649095e-11 BR00118039 HTR2C final orf M06 U2OS 96 5322 Interphase +0.06580278763150875 6.63231913721672e-11 BR00118040 DHH final orf G05 U2OS 96 5556 Interphase +0.07149737870732295 7.011131101797121e-11 BR00118040 KCNH7 final orf A22 U2OS 96 4692 Interphase +0.07101017539161869 7.287846600300722e-11 BR00118040 AGER final orf H18 U2OS 96 4752 Interphase +0.06379085804827622 9.169138879680318e-11 BR00118039 DCK final orf D05 U2OS 96 5838 Interphase +0.05817211477588836 9.709071677463485e-11 BR00118039 PIK3CG final orf G18 U2OS 96 6996 Interphase +0.06225296442687747 1.1901699625884673e-10 BR00118040 CLK1 final orf D08 U2OS 96 6072 Interphase +0.06020309845287833 1.5666782498253878e-10 BR00118039 P3H1 final orf F23 U2OS 96 6408 Interphase +0.07075698968512487 1.7559778552482785e-10 BR00118040 TUBB3 final orf K05 U2OS 96 4608 Interphase +0.08212423932933316 2.5753328577411836e-10 BR00118040 SLC7A11 final orf A03 U2OS 96 3360 Interphase +0.068934793288191 2.646571916477621e-10 BR00118040 NAMPT final orf D13 U2OS 96 4776 Interphase +0.07382857811266315 2.7235135191110543e-10 BR00118040 ABL1 final orf M24 U2OS 96 4152 Interphase +0.060153994225216556 3.156420933252974e-10 BR00118040 P3H1 final orf P24 U2OS 96 6234 Interphase +0.07107512370670266 3.465451320845734e-10 BR00118040 CDC25A final orf I19 U2OS 96 4446 Interphase +0.05595200073002692 4.5972609971958254e-10 BR00118039 TUBB4B final orf E04 U2OS 96 7068 Interphase +0.06940818102697999 4.770212627497562e-10 BR00118040 KDR final orf O02 U2OS 96 4596 Interphase +0.10729166666666666 4.855449768129641e-10 BR00118039 SLCO2B1 final orf A02 U2OS 96 1920 Interphase +0.0634002895954802 5.775228171156715e-10 BR00118040 PIK3CG final orf G18 U2OS 96 5436 Interphase +0.06395786305492852 7.103049687494666e-10 BR00118040 CACNB4 final orf A18 U2OS 96 5316 Interphase +0.06501164150117451 7.806739146562949e-10 BR00118040 GABRB2 final orf C06 U2OS 96 5106 Interphase +0.05613881598133567 8.13166024681031e-10 BR00118039 CDK7 final orf M21 U2OS 96 6858 Interphase +0.059196318806689546 8.187590557318089e-10 BR00118040 KCNN4 final orf O17 U2OS 96 6156 Interphase +0.07382457780634605 9.013876387804332e-10 BR00118040 DDR2 final orf A19 U2OS 96 3924 Interphase +0.06485642256902761 1.32924612838489e-09 BR00118040 BRD4 final orf F14 U2OS 96 4998 Interphase +0.0776402566620055 1.4339460833427635e-09 BR00118040 OPRM1 final orf A08 U2OS 96 3480 Interphase +0.06311018131101813 1.537175193127615e-09 BR00118039 TNNC1 final orf M18 U2OS 96 5256 Interphase +0.062189835979650325 1.7634188178340143e-09 BR00118040 HIF1A final orf C23 U2OS 96 5370 Interphase +0.05333023345665452 1.8031569317749443e-09 BR00118040 P3H1 final orf F23 U2OS 96 7308 Interphase +0.059112659371110085 1.8599330304822873e-09 BR00118040 PAK4 final orf G10 U2OS 96 5928 Interphase +0.061482560381649204 2.156078088177012e-09 BR00118039 GPR119 final orf N23 U2OS 96 5436 Interphase +0.07591036414565826 2.2882581531197356e-09 BR00118039 AKR1B1 final orf L17 U2OS 96 3570 Interphase +0.05847359896839105 2.3904337451998957e-09 BR00118039 DNMT3A final orf F04 U2OS 96 5982 Interphase +0.05671103105935058 2.5021759982966652e-09 BR00118040 RET final orf K10 U2OS 96 6342 Interphase +0.08529621698786581 2.744163339087598e-09 BR00118040 PDPK1 final orf H15 U2OS 96 2802 Interphase +0.06649053280493175 3.75716780427837e-09 BR00118040 PLA2G1B final orf E06 U2OS 96 4542 Interphase +0.05946683353529033 4.089149190075968e-09 BR00118040 RPL3 final orf G09 U2OS 96 5628 Interphase +0.0588972849952077 4.096140643820368e-09 BR00118039 AVPR1A final orf H22 U2OS 96 5748 Interphase +0.05590249235973419 5.529815301562226e-09 BR00118039 GPR55 final orf F13 U2OS 96 6288 Interphase 0.2698390247900237 4.992628294968698e-97 BR00118039 DYRK1B final orf G13 U2OS 96 3012 Large 0.936046511627907 5.942968692757089e-83 BR00118040 GRIN2A final orf A05 U2OS 96 174 Large 0.18661284273958903 3.1487231967168834e-51 BR00118040 DYRK1B final orf G13 U2OS 96 3336 Large @@ -1739,6 +17309,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.12134502923976608 9.888328813731906e-27 BR00118039 CACNB4 final orf M01 U2OS 96 4104 Large 0.09826793920113114 3.437659298638952e-24 BR00118040 ITGB2 final orf B12 U2OS 96 5658 Large 0.11966730981773224 4.053404173480252e-24 BR00118040 KRAS final orf F08 U2OS 96 3798 Large +0.1046562228024369 2.5182972008811197e-22 BR00118040 KDR final orf O02 U2OS 96 4596 Large +0.14280957417636228 6.058623722539427e-22 BR00118040 LYN final orf M05 U2OS 96 2412 Large +0.10518914290077427 2.9976976115156355e-21 BR00118040 CHRM3 final orf A11 U2OS 96 4314 Large +0.13231889423670246 4.904899711226685e-21 BR00118040 DYRK1B final orf M12 U2OS 96 2700 Large +0.15447146393767025 2.7478801291668664e-20 BR00118040 CLK1 final orf J17 U2OS 96 1902 Large +0.09139626844258725 6.490121774234336e-20 BR00118040 CHRM2 final orf B08 U2OS 96 5346 Large +0.0779039582347757 4.2774203541212305e-19 BR00118039 TUBB4B final orf E04 U2OS 96 7068 Large +0.08610137424230152 8.542578275954283e-19 BR00118040 CDK2 final orf L03 U2OS 96 5682 Large +0.10031463969264318 1.2841039581112317e-18 BR00118040 ABL1 final orf M24 U2OS 96 4152 Large +0.10469409282700422 1.6575998174071211e-18 BR00118039 DNMT3A final orf H07 U2OS 96 3792 Large +0.09542444716688238 2.0737341970142855e-18 BR00118039 GRIN2A final orf A05 U2OS 96 4524 Large +0.07501571652515049 1.4056672226883504e-17 BR00118039 PIK3CG final orf G18 U2OS 96 6996 Large +0.08352391116531992 1.6102371603544452e-17 BR00118039 AKT1 final orf J16 U2OS 96 5628 Large +0.09401709401709402 1.6230159503083376e-17 BR00118040 CDC25A final orf I19 U2OS 96 4446 Large +0.1110056925996205 2.2252708882266885e-17 BR00118040 ABL1 final orf C01 U2OS 96 3162 Large +0.09407824099303286 2.4662327102840184e-17 BR00118040 SCNN1G final orf A04 U2OS 96 4386 Large +0.10372233846290219 2.5251933457540436e-17 BR00118040 ELANE final orf D19 U2OS 96 3606 Large +0.09022185648071031 5.875148847533222e-17 BR00118039 CHRM3 final orf A11 U2OS 96 4662 Large +0.08520710059171598 1.9818157961087364e-16 BR00118039 ERBB2 final orf E21 U2OS 96 5070 Large +0.07707352920394002 2.0523052111017844e-16 BR00118040 PTGIS final orf F16 U2OS 96 6180 Large +0.0889225443530939 2.4544445490526677e-16 BR00118040 CDC25A final orf M04 U2OS 96 4620 Large +0.07973376610006971 3.0106134285900006e-16 BR00118039 PPARD final orf M07 U2OS 96 5712 Large +0.09511939856115431 3.051052557872545e-16 BR00118040 CHRM3 final orf A10 U2OS 96 4002 Large +0.10668511108208556 3.092802273396046e-16 BR00118040 LYN final orf C20 U2OS 96 3180 Large +0.0722200778028186 5.680932208732453e-16 BR00118039 HCK final orf O20 U2OS 96 6834 Large +0.09254603299735345 7.3213071265205905e-16 BR00118039 IMPDH1 final orf L13 U2OS 96 4128 Large +0.0696362586734774 7.440552227667484e-16 BR00118040 P3H1 final orf F23 U2OS 96 7308 Large +0.08558558558558559 2.8437931097320976e-15 BR00118040 PRKCB final orf K19 U2OS 96 4662 Large +0.0811682870349513 3.1459867819137717e-15 BR00118039 CA5A final orf B23 U2OS 96 5160 Large +0.08960969404833635 3.6599212778823166e-15 BR00118040 PPAT final orf H14 U2OS 96 4212 Large +0.08151407430763372 5.781837468649724e-15 BR00118039 F10 final orf C09 U2OS 96 5028 Large +0.07135746257138448 8.957209524365565e-15 BR00118040 CACNG1 final orf E23 U2OS 96 6480 Large +0.08586056051665751 3.4456659247274005e-14 BR00118039 BTK final orf P10 U2OS 96 4290 Large +0.07301353240034145 5.102661474423569e-14 BR00118039 SLC7A11 final orf G24 U2OS 96 5844 Large +0.12708333333333333 6.32895940852591e-14 BR00118039 SLCO2B1 final orf A02 U2OS 96 1920 Large +0.07673099955660018 1.085276790389642e-13 BR00118039 EDNRB final orf M08 U2OS 96 5178 Large +0.06506935088737738 2.228659946535319e-13 BR00118039 CHRM2 final orf B08 U2OS 96 7020 Large +0.07612512443430318 2.5436397894374544e-13 BR00118040 RNASE1 final orf I18 U2OS 96 5106 Large +0.07620008891492289 3.1176678790187296e-13 BR00118040 TBXAS1 final orf P23 U2OS 96 5070 Large +0.07133727229326092 3.6538630011983063e-13 BR00118039 AVPR1A final orf H22 U2OS 96 5748 Large +0.10270813306648596 4.1923199578029806e-13 BR00118039 CLK1 final orf D08 U2OS 96 2760 Large +0.09041950113378684 5.740835065379632e-13 BR00118040 IMPDH1 final orf L13 U2OS 96 3528 Large +0.07063359973634341 7.555355176920146e-13 BR00118039 P2RY12 final orf B01 U2OS 96 5724 Large +0.06945659189625278 1.0567236147040345e-12 BR00118039 DCK final orf D05 U2OS 96 5838 Large +0.08460754332313965 1.2268455810789738e-12 BR00118039 PPARD final orf I12 U2OS 96 3924 Large +0.06313993174061433 1.3143983105074727e-12 BR00118039 CDC25A final orf I19 U2OS 96 7032 Large +0.07456140350877193 1.5145143199121593e-12 BR00118040 TUBB3 final orf G06 U2OS 96 5016 Large +0.07247476685454737 1.9459562234669392e-12 BR00118040 TUBB final orf M16 U2OS 96 5238 Large +0.11652692280478313 2.1727376667250194e-12 BR00118040 KCNN1 final orf A01 U2OS 96 2016 Large +0.06473829201101929 2.516352198219312e-12 BR00118040 TUBB final orf E19 U2OS 96 6534 Large +0.08476242220892156 2.7296838489504535e-12 BR00118039 KRAS final orf D17 U2OS 96 3786 Large +0.08116419389628939 4.376226753106211e-12 BR00118039 HTR3A final orf H24 U2OS 96 4056 Large +0.07034050160709028 4.796573799997904e-12 BR00118039 ADH1C final orf M23 U2OS 96 5388 Large +0.09601877607788595 5.193283950241545e-12 BR00118040 GPR55 final orf F13 U2OS 96 2880 Large +0.0595855325187842 6.0428919584514746e-12 BR00118039 CYP3A4 final orf K22 U2OS 96 7452 Large +0.07617789520035227 6.9864636420980694e-12 BR00118040 PLA2G1B final orf E06 U2OS 96 4542 Large +0.06687270433051297 1.4278466487067247e-11 BR00118039 CCND1 final orf P16 U2OS 96 5718 Large +0.08717126260691944 1.4366415189594609e-11 BR00118040 SLC7A11 final orf A03 U2OS 96 3360 Large +0.0695352678501644 1.685573920825087e-11 BR00118039 TNNC1 final orf M18 U2OS 96 5256 Large +0.06998393232380602 1.916010349182446e-11 BR00118039 DDR2 final orf M02 U2OS 96 5154 Large +0.06533948973314009 2.045492605070382e-11 BR00118040 PIK3CG final orf I03 U2OS 96 5904 Large +0.07786729973983773 2.3943375435155286e-11 BR00118040 RET final orf E03 U2OS 96 4140 Large +0.08137400721196286 2.7008703742501923e-11 BR00118040 SLCO2B1 final orf A02 U2OS 96 3762 Large +0.06217935207326667 2.7971414753846958e-11 BR00118039 CDK7 final orf K06 U2OS 96 6444 Large +0.08264915161466886 2.8192525948874082e-11 BR00118040 KCNN4 final orf A06 U2OS 96 3654 Large +0.07828224674404585 3.177239308160577e-11 BR00118040 SSTR2 final orf J01 U2OS 96 4044 Large +0.08563315829120093 4.773180271142231e-11 BR00118039 MAPK8 final orf I14 U2OS 96 3324 Large +0.07303096030040603 5.064885091341961e-11 BR00118039 CHEK2 final orf H06 U2OS 96 4566 Large +0.08235294117647059 5.964223240848206e-11 BR00118039 AKR1B1 final orf L17 U2OS 96 3570 Large +0.06482446993395899 6.216445103988751e-11 BR00118040 SLC7A11 final orf G24 U2OS 96 5754 Large +0.07597096876161884 7.502956661632335e-11 BR00118040 CACNB4 final orf M01 U2OS 96 4152 Large +0.0717582107908851 1.0157237114608503e-10 BR00118040 MET final orf C03 U2OS 96 4584 Large +0.06278219582699293 1.0234900560388728e-10 BR00118039 DNMT3A final orf F04 U2OS 96 5982 Large +0.06722923390416234 1.0934432205126433e-10 BR00118040 ADA final orf P04 U2OS 96 5208 Large +0.07786693574220001 1.1475396799953716e-10 BR00118040 CYP2A6 final orf A15 U2OS 96 3870 Large +0.062384500549136176 1.1705771758563902e-10 BR00118039 CDC25A final orf M04 U2OS 96 6042 Large +0.06580691326469347 1.217564441219677e-10 BR00118039 KDR final orf O02 U2OS 96 5406 Large +0.07781045338914247 1.2219235752729052e-10 BR00118039 AGER final orf H09 U2OS 96 3870 Large +0.07513460597161038 1.884670345917555e-10 BR00118039 SIRT2 final orf A07 U2OS 96 4086 Large +0.058678166868679035 2.370543509328559e-10 BR00118039 CDK2 final orf J04 U2OS 96 6606 Large +0.062356507954023505 2.62270383925976e-10 BR00118039 BAX final orf G12 U2OS 96 5844 Large +0.06387751284531101 3.5389372356343197e-10 BR00118039 BTK final orf N01 U2OS 96 5490 Large +0.06855345911949685 3.621110197820839e-10 BR00118039 CLK1 final orf J17 U2OS 96 4770 Large +0.08029088898492259 3.720979181716478e-10 BR00118040 NTRK1 final orf D01 U2OS 96 3468 Large +0.06481543527686545 4.574579381440254e-10 BR00118040 HDAC6 final orf K03 U2OS 96 5268 Large +0.08262533940508926 4.606692548892173e-10 BR00118040 CCND1 final orf P16 U2OS 96 3228 Large +0.05777374470659407 5.149015332043289e-10 BR00118039 GABRB2 final orf C19 U2OS 96 6612 Large +0.0566873339238264 6.96569739570879e-10 BR00118039 MME final orf I11 U2OS 96 6774 Large +0.0926289304736054 9.821251976614404e-10 BR00118039 IGF1R final orf H05 U2OS 96 2478 Large +0.05913318714658706 1.047562101611742e-09 BR00118039 ATP5F1D final orf G14 U2OS 96 6084 Large 0.1632449505444269 2.0301630702446134e-37 BR00118040 LYN final orf C20 U2OS 96 3180 Metaphase 0.1595185284079343 6.534917067252903e-34 BR00118039 DYRK1B final orf G13 U2OS 96 3012 Metaphase 0.12579539892315222 1.4092375606327035e-28 BR00118039 LYN final orf M05 U2OS 96 4086 Metaphase @@ -1749,6 +17409,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.11631880882713291 1.5316541092370786e-24 BR00118039 LYN final orf C20 U2OS 96 4080 Metaphase 0.13718787280431116 1.3358830836151775e-22 BR00118040 DYRK1B final orf M12 U2OS 96 2700 Metaphase 0.09644071539623082 5.182940323486741e-22 BR00118040 HSP90AB1 final orf P01 U2OS 96 5334 Metaphase +0.10947378987445239 8.869694722682408e-22 BR00118039 P3H1 final orf P24 U2OS 96 4092 Metaphase +0.14077870077709256 2.3164019134449658e-21 BR00118040 LYN final orf M05 U2OS 96 2412 Metaphase +0.10301663815891775 4.181959865808404e-20 BR00118040 NTRK1 final orf P02 U2OS 96 4248 Metaphase +0.0950467978126326 1.0357697819805098e-19 BR00118040 HPGDS final orf O24 U2OS 96 4896 Metaphase +0.09172817256232174 1.6564423103160284e-19 BR00118040 ADA final orf P04 U2OS 96 5208 Metaphase +0.10681303036547216 2.567765910828508e-19 BR00118040 KRAS final orf F08 U2OS 96 3798 Metaphase +0.08948733435623867 3.882635787387246e-19 BR00118040 GHSR final orf C24 U2OS 96 5364 Metaphase +0.08461808795939643 1.6820230976243438e-18 BR00118040 CCR1 final orf F24 U2OS 96 5796 Metaphase +0.07855611903218548 2.0688964581743733e-18 BR00118039 TBXAS1 final orf J24 U2OS 96 6684 Metaphase +0.14475445458496305 2.8530788761919572e-18 BR00118039 DYRK1B final orf M12 U2OS 96 1950 Metaphase +0.0811454746917597 2.901390907027365e-18 BR00118040 HTR2C final orf G21 U2OS 96 6228 Metaphase +0.08084696823869104 3.8635272632973164e-18 BR00118040 P3H1 final orf P24 U2OS 96 6234 Metaphase +0.1514010825669655 4.4602682935142344e-18 BR00118040 KRAS final orf D17 U2OS 96 1764 Metaphase +0.08256198030532683 9.284999520506974e-18 BR00118039 SLC7A11 final orf G24 U2OS 96 5844 Metaphase +0.08653122648607976 9.867528601482444e-18 BR00118040 CACNB4 final orf A18 U2OS 96 5316 Metaphase +0.075451773610942 1.7817608522800434e-17 BR00118039 FGF1 final orf F22 U2OS 96 6876 Metaphase +0.08117594152080812 5.0185990231114486e-17 BR00118039 BRD4 final orf F14 U2OS 96 5778 Metaphase +0.07191109847664429 7.547422706996484e-17 BR00118040 MAPK14 final orf G22 U2OS 96 7296 Metaphase +0.09989053092501368 2.769319053118384e-16 BR00118040 KCNN4 final orf A06 U2OS 96 3654 Metaphase +0.08230581365905912 2.269739896425966e-15 BR00118040 TBXAS1 final orf P23 U2OS 96 5070 Metaphase +0.08967106157401114 3.789127325627478e-15 BR00118040 CDK4 final orf P20 U2OS 96 4200 Metaphase +0.08728971220807577 3.441009177830147e-14 BR00118040 CACNB4 final orf M01 U2OS 96 4152 Metaphase +0.0705242706703256 4.670935969125761e-14 BR00118039 ADORA2A final orf O18 U2OS 96 6300 Metaphase +0.07378472222222222 4.6881834265808357e-14 BR00118040 ASIC1 final orf F12 U2OS 96 5760 Metaphase +0.0864385299626126 6.608264893505993e-14 BR00118040 CCR1 final orf P17 U2OS 96 4134 Metaphase +0.09050506182239187 7.2979100307517e-14 BR00118039 KRAS final orf F08 U2OS 96 3762 Metaphase +0.07598010027685065 9.42636150189949e-14 BR00118039 RPL3 final orf G09 U2OS 96 5298 Metaphase +0.07119409543813535 1.2823361651322824e-13 BR00118039 TUBB3 final orf G06 U2OS 96 5976 Metaphase +0.0929295792359598 1.809739112614077e-13 BR00118040 NTRK1 final orf D01 U2OS 96 3468 Metaphase +0.09373004698253182 1.879904866366451e-13 BR00118040 LPAR1 final orf B20 U2OS 96 3396 Metaphase +0.0854075158613958 2.0164428417788922e-13 BR00118040 COMT final orf P09 U2OS 96 4098 Metaphase +0.07243102387435958 2.969038295547623e-13 BR00118040 KCTD16 final orf M22 U2OS 96 5616 Metaphase +0.07278350808572513 5.399004147078198e-13 BR00118040 KCNQ2 final orf K01 U2OS 96 5436 Metaphase +0.1270433258433907 7.343470141772705e-13 BR00118039 KCNMA1 final orf G01 U2OS 96 1764 Metaphase +0.07812543005455155 7.859750234727217e-13 BR00118040 UGT1A9 final orf E24 U2OS 96 4668 Metaphase +0.0802504035790572 8.376926912966445e-13 BR00118039 GAA final orf N04 U2OS 96 4416 Metaphase +0.07399196273303119 1.0033835054281703e-12 BR00118039 CA5A final orf B23 U2OS 96 5160 Metaphase +0.0688127909826023 1.1337546125337122e-12 BR00118039 BAX final orf K17 U2OS 96 5940 Metaphase +0.06541811501488921 1.4827917575035884e-12 BR00118039 USP1 final orf E12 U2OS 96 6510 Metaphase +0.07322472811151258 1.7874505761525578e-12 BR00118039 SLCO2B1 final orf O13 U2OS 96 5160 Metaphase +0.08177954468395326 2.21903254909559e-12 BR00118040 SIRT2 final orf A07 U2OS 96 4092 Metaphase +0.08173313638601674 3.195760061106903e-12 BR00118039 CASP3 final orf J10 U2OS 96 4062 Metaphase +0.0684233987168974 3.2417801005681325e-12 BR00118039 PTGIR final orf C07 U2OS 96 5778 Metaphase +0.07861759346753905 7.15429550875663e-12 BR00118040 P2RY12 final orf B01 U2OS 96 4248 Metaphase +0.07317174585390598 8.250715999764934e-12 BR00118040 ANXA1 final orf N24 U2OS 96 4878 Metaphase +0.08062564568752864 8.596638930761575e-12 BR00118040 CHRM3 final orf A10 U2OS 96 4002 Metaphase +0.07069591664375485 1.0349826641848935e-11 BR00118039 ABL1 final orf M24 U2OS 96 5172 Metaphase +0.07506682837059711 1.0888599823751572e-11 BR00118040 MET final orf C03 U2OS 96 4584 Metaphase +0.08254219409282701 1.1733663084855224e-11 BR00118039 DNMT3A final orf H07 U2OS 96 3792 Metaphase +0.09151740879535843 1.2003272541640103e-11 BR00118040 ALDH2 final orf P14 U2OS 96 3066 Metaphase +0.07030703110198139 1.216375264239492e-11 BR00118039 KCNMA1 final orf O08 U2OS 96 5202 Metaphase +0.08793076041540537 2.6137078099156107e-11 BR00118040 LPAR1 final orf B05 U2OS 96 3234 Metaphase +0.0737597911227154 2.7101909348661584e-11 BR00118040 KDR final orf O02 U2OS 96 4596 Metaphase +0.06617421242965284 4.6658525399192955e-11 BR00118040 CDK2 final orf J04 U2OS 96 5580 Metaphase +0.0663966272457643 9.748545329035836e-11 BR00118040 S1PR1 final orf L01 U2OS 96 5370 Metaphase +0.07286525998100557 1.0275405323116499e-10 BR00118039 LCK final orf H01 U2OS 96 4452 Metaphase +0.057871548695985695 1.806995613452597e-10 BR00118040 ADORA2A final orf O23 U2OS 96 6888 Metaphase +0.06361564762088064 1.9090876136358462e-10 BR00118040 CDK2 final orf L03 U2OS 96 5682 Metaphase +0.08049547271230649 2.942432800389797e-10 BR00118040 OPRM1 final orf A08 U2OS 96 3480 Metaphase +0.06395779795910783 3.40565591667661e-10 BR00118040 CACNA2D3 final orf P19 U2OS 96 5478 Metaphase +0.06293312010109087 3.9699726682537584e-10 BR00118040 RPL3 final orf G09 U2OS 96 5628 Metaphase +0.055720087830932796 4.688048193015564e-10 BR00118039 GHSR final orf C24 U2OS 96 7116 Metaphase +0.10163903015400337 5.016982769058599e-10 BR00118040 PTK2B final orf J18 U2OS 96 2124 Metaphase +0.06853980417198809 5.125475258709514e-10 BR00118040 CACNG1 final orf A16 U2OS 96 4698 Metaphase +0.06940955426513201 5.398147069759393e-10 BR00118039 HSD11B1 final orf C02 U2OS 96 4560 Metaphase +0.06555139303154467 5.877199755345047e-10 BR00118040 KDR final orf A21 U2OS 96 5082 Metaphase +0.07683181020879101 9.08008187019077e-10 BR00118040 ADRA2B final orf N18 U2OS 96 3636 Metaphase +0.06703687410609355 9.405130362907767e-10 BR00118040 FFAR2 final orf B15 U2OS 96 4752 Metaphase +0.06428324662308921 1.1154792485413161e-09 BR00118039 PDPK1 final orf D06 U2OS 96 5130 Metaphase +0.06926460482428204 1.8613117596558067e-09 BR00118040 CHRM3 final orf A11 U2OS 96 4314 Metaphase +0.06069358384200608 2.1141773685686213e-09 BR00118040 RPL3 final orf K12 U2OS 96 5586 Metaphase +0.061093333970126444 2.3290910190441447e-09 BR00118039 BTK final orf N01 U2OS 96 5490 Metaphase +0.05593544424189585 2.605431724449174e-09 BR00118039 EDNRB final orf K11 U2OS 96 6510 Metaphase +0.08032890575585072 2.7023114477853194e-09 BR00118040 ABL1 final orf C01 U2OS 96 3162 Metaphase +0.0636397920102338 2.956414999855955e-09 BR00118039 LPAR1 final orf B05 U2OS 96 4992 Metaphase +0.07033502142578886 3.1402864111964283e-09 BR00118040 FOXM1 final orf P15 U2OS 96 4080 Metaphase +0.06197514203188531 3.246125899044918e-09 BR00118039 TNNC1 final orf G07 U2OS 96 5256 Metaphase +0.0662703654777631 4.291374874775861e-09 BR00118040 PLA2G1B final orf E06 U2OS 96 4542 Metaphase +0.0706875530214848 6.056359339028931e-09 BR00118040 GJB4 final orf H23 U2OS 96 3900 Metaphase +0.05721772985923929 6.789349557182362e-09 BR00118040 S1PR4 final orf M17 U2OS 96 5940 Metaphase +0.05862557562876373 7.40338833670944e-09 BR00118039 ALK final orf J13 U2OS 96 5646 Metaphase +0.06894819369535211 8.380053463765613e-09 BR00118040 SSTR2 final orf J01 U2OS 96 4044 Metaphase +0.06015734455987074 8.482317133841514e-09 BR00118039 KCNJ1 final orf M03 U2OS 96 5298 Metaphase +0.06785503125175966 9.976682569839152e-09 BR00118039 IMPDH1 final orf L13 U2OS 96 4128 Metaphase +0.06058350163202918 1.001670446144171e-08 BR00118039 EDNRB final orf M08 U2OS 96 5178 Metaphase +0.05752519986096628 1.0662294768983613e-08 BR00118040 SLC7A11 final orf G24 U2OS 96 5754 Metaphase +0.05914504061602221 1.1968636169414257e-08 BR00118039 HTR2C final orf G21 U2OS 96 5394 Metaphase +0.060596368164806166 1.3666758159201333e-08 BR00118040 GABRB2 final orf C06 U2OS 96 5106 Metaphase +0.08088235294117647 1.511134636802462e-08 BR00118040 CDK9 final orf H11 U2OS 96 2856 Metaphase +0.06058187164216242 1.8208900731820637e-08 BR00118039 F10 final orf C09 U2OS 96 5028 Metaphase 0.14508381812306556 4.635506820140201e-40 BR00118040 CHRM3 final orf A11 U2OS 96 4314 MetaphaseAlignment 0.1539733325881734 2.0377305617627398e-39 BR00118040 SLCO2B1 final orf A02 U2OS 96 3762 MetaphaseAlignment 0.14849671243654347 5.238988734785426e-37 BR00118040 KRAS final orf F08 U2OS 96 3798 MetaphaseAlignment @@ -1759,6 +17509,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.5551323175621492 3.951166768554011e-25 BR00118040 GRIN2A final orf A05 U2OS 96 174 MetaphaseAlignment 0.11597719705377862 2.443066041807984e-24 BR00118039 LYN final orf C20 U2OS 96 4080 MetaphaseAlignment 0.12252276856216679 2.9723488364208314e-21 BR00118040 LYN final orf C20 U2OS 96 3180 MetaphaseAlignment +0.10164054017372422 3.733537898600382e-21 BR00118040 TUBB3 final orf K05 U2OS 96 4608 MetaphaseAlignment +0.08486499940480699 1.220984724994091e-20 BR00118039 AKT1 final orf F15 U2OS 96 6450 MetaphaseAlignment +0.09273890142964634 2.6198746520270356e-20 BR00118040 CACNB4 final orf A18 U2OS 96 5316 MetaphaseAlignment +0.09209586798769012 3.03031060360928e-20 BR00118040 GHSR final orf C24 U2OS 96 5364 MetaphaseAlignment +0.10548213411649535 3.329955380000131e-20 BR00118039 LYN final orf M05 U2OS 96 4086 MetaphaseAlignment +0.10654982431303718 3.3373726082231803e-20 BR00118040 CHRM3 final orf A10 U2OS 96 4002 MetaphaseAlignment +0.12175980880723952 6.80814412530642e-20 BR00118039 DYRK1B final orf G13 U2OS 96 3012 MetaphaseAlignment +0.0897281260384103 1.4512864843839487e-19 BR00118039 HCK final orf O01 U2OS 96 5454 MetaphaseAlignment +0.0964245740085926 9.13061308866865e-19 BR00118040 SIRT2 final orf G02 U2OS 96 4518 MetaphaseAlignment +0.10727969348659004 1.0108456319519206e-18 BR00118040 KCNN4 final orf A06 U2OS 96 3654 MetaphaseAlignment +0.08957676730077865 3.855147748991383e-18 BR00118040 TBXAS1 final orf P23 U2OS 96 5070 MetaphaseAlignment +0.07608451570894596 6.7770277047573605e-18 BR00118039 KCNH7 final orf A22 U2OS 96 6924 MetaphaseAlignment +0.0784771884092767 8.396794056769928e-18 BR00118040 CACNG1 final orf E23 U2OS 96 6480 MetaphaseAlignment +0.09554581374671563 2.4532806841229593e-17 BR00118040 P2RY12 final orf B01 U2OS 96 4248 MetaphaseAlignment +0.09189594051814329 3.804957538870671e-17 BR00118039 CDK4 final orf P20 U2OS 96 4542 MetaphaseAlignment +0.09361172751240367 7.838012935300023e-17 BR00118039 ADA final orf P03 U2OS 96 4290 MetaphaseAlignment +0.08643457382953182 1.1640306976904496e-16 BR00118039 SLC7A11 final orf A03 U2OS 96 4998 MetaphaseAlignment +0.08842306908946786 2.5683135172129916e-16 BR00118039 CACNB4 final orf A18 U2OS 96 4668 MetaphaseAlignment +0.09040484533580136 2.6735525756011607e-16 BR00118039 LCK final orf H01 U2OS 96 4452 MetaphaseAlignment +0.07934854851555849 4.1140797993480497e-16 BR00118039 P2RY12 final orf B01 U2OS 96 5724 MetaphaseAlignment +0.1359375 7.057268955214101e-16 BR00118039 SLCO2B1 final orf A02 U2OS 96 1920 MetaphaseAlignment +0.09186818112688007 5.042782320098232e-15 BR00118039 HSP90AB1 final orf P01 U2OS 96 3966 MetaphaseAlignment +0.07549296414431986 7.331030621975675e-15 BR00118039 TUBB final orf E19 U2OS 96 5814 MetaphaseAlignment +0.08957415565345081 1.1109806182048978e-14 BR00118039 SIRT2 final orf A07 U2OS 96 4086 MetaphaseAlignment +0.09963445620395346 4.1415235119939215e-14 BR00118040 PRKCE final orf J19 U2OS 96 3156 MetaphaseAlignment +0.08900718751826098 5.853150197282778e-14 BR00118040 DDR2 final orf A19 U2OS 96 3924 MetaphaseAlignment +0.12561811070285647 6.993781132904154e-14 BR00118039 DYRK1B final orf M12 U2OS 96 1950 MetaphaseAlignment +0.08782742681047766 1.741783170975019e-13 BR00118040 ITGB2 final orf P21 U2OS 96 3894 MetaphaseAlignment +0.09254857040849722 1.9953068618406667e-13 BR00118040 OPRM1 final orf A08 U2OS 96 3480 MetaphaseAlignment +0.07081172827500239 3.6651306291338974e-13 BR00118039 DCK final orf D05 U2OS 96 5838 MetaphaseAlignment +0.07207407087143942 3.714034924087884e-13 BR00118039 ANXA1 final orf D23 U2OS 96 5628 MetaphaseAlignment +0.0747599809507286 4.0307237593807e-13 BR00118040 ADA final orf P04 U2OS 96 5208 MetaphaseAlignment +0.08672120251137165 4.1714996059433235e-13 BR00118040 CYP2A6 final orf A15 U2OS 96 3870 MetaphaseAlignment +0.08747104259158658 4.3540487109057684e-13 BR00118040 OPRL1 final orf A23 U2OS 96 3798 MetaphaseAlignment +0.06851119894598155 8.216209391673938e-13 BR00118040 CLK1 final orf D08 U2OS 96 6072 MetaphaseAlignment +0.08362583993276138 8.933459814925225e-13 BR00118040 SSTR2 final orf J01 U2OS 96 4044 MetaphaseAlignment +0.06998282707137451 9.286924888521016e-13 BR00118039 BRD4 final orf F14 U2OS 96 5778 MetaphaseAlignment +0.07146531185593989 1.025553689889652e-12 BR00118039 SSTR2 final orf J01 U2OS 96 5532 MetaphaseAlignment +0.08017918536688169 1.0514559853980595e-12 BR00118040 SCNN1G final orf A04 U2OS 96 4386 MetaphaseAlignment +0.07514571773993386 1.7835865756894903e-12 BR00118040 HPGDS final orf O24 U2OS 96 4896 MetaphaseAlignment +0.07717678565334944 2.1102880632325532e-12 BR00118040 HIF1A final orf A12 U2OS 96 4614 MetaphaseAlignment +0.08085697018477336 2.7814979287792535e-12 BR00118040 CACNB4 final orf M01 U2OS 96 4152 MetaphaseAlignment +0.12375392835908483 2.951502827701197e-12 BR00118039 KCNMA1 final orf G01 U2OS 96 1764 MetaphaseAlignment +0.08165527839521418 3.1929066145872263e-12 BR00118039 PNLIP final orf L22 U2OS 96 4050 MetaphaseAlignment +0.06457777153294927 3.648747857422812e-12 BR00118039 KCNJ1 final orf E22 U2OS 96 6468 MetaphaseAlignment +0.08942911578466406 4.489571238772172e-12 BR00118040 DYRK1B final orf G13 U2OS 96 3336 MetaphaseAlignment +0.07855336092118521 6.278584174999722e-12 BR00118040 HTR2C final orf M06 U2OS 96 4272 MetaphaseAlignment +0.06096269765641829 8.662589659796212e-12 BR00118039 CHRM2 final orf B08 U2OS 96 7020 MetaphaseAlignment +0.10343640273559677 1.0328872878377808e-11 BR00118040 LYN final orf M05 U2OS 96 2412 MetaphaseAlignment +0.06118509403010299 1.1613662072766663e-11 BR00118040 ADORA2A final orf O23 U2OS 96 6888 MetaphaseAlignment +0.07338029902495521 1.2334103710932533e-11 BR00118040 NAMPT final orf D13 U2OS 96 4776 MetaphaseAlignment +0.06107974146678031 1.3259817166315001e-11 BR00118039 FGF1 final orf F22 U2OS 96 6876 MetaphaseAlignment +0.07303296528995533 1.3684991922289473e-11 BR00118039 OPRM1 final orf A09 U2OS 96 4812 MetaphaseAlignment +0.07873062015503876 1.507934039134707e-11 BR00118040 AKR1C1 final orf A24 U2OS 96 4128 MetaphaseAlignment +0.07356459577966339 1.9957998760730676e-11 BR00118039 CHRM3 final orf A11 U2OS 96 4662 MetaphaseAlignment +0.0783656420538325 2.0963728444657993e-11 BR00118040 SIRT2 final orf A07 U2OS 96 4092 MetaphaseAlignment +0.06798060969393453 2.256577329749777e-11 BR00118040 PIK3CG final orf G18 U2OS 96 5436 MetaphaseAlignment +0.06599162746963123 2.4200235556470087e-11 BR00118039 AVPR1A final orf H22 U2OS 96 5748 MetaphaseAlignment +0.06655281300465199 2.7859246845702488e-11 BR00118039 AKT1 final orf J16 U2OS 96 5628 MetaphaseAlignment +0.4624624624624625 3.587836394956043e-11 BR00118039 SCNN1G final orf A04 U2OS 96 108 MetaphaseAlignment +0.06906173990149639 3.6528916832093694e-11 BR00118039 ABL1 final orf M24 U2OS 96 5172 MetaphaseAlignment +0.07217858433142883 4.787064406854471e-11 BR00118039 JAK1 final orf D18 U2OS 96 4674 MetaphaseAlignment +0.06355711612455583 6.155003219872043e-11 BR00118040 P2RY12 final orf B24 U2OS 96 5970 MetaphaseAlignment +0.06681721270625117 6.568134624861822e-11 BR00118040 IL1B final orf E15 U2OS 96 5388 MetaphaseAlignment +0.06743749357801065 1.1625858902243535e-10 BR00118039 DDR2 final orf M02 U2OS 96 5154 MetaphaseAlignment +0.07866525610508683 1.3188197994224798e-10 BR00118039 CYP2A6 final orf A15 U2OS 96 3780 MetaphaseAlignment +0.10701903346777046 1.5740023313515107e-10 BR00118040 KCNN1 final orf A01 U2OS 96 2016 MetaphaseAlignment +0.05984635810204368 1.5760211397383413e-10 BR00118039 GLRA3 final orf K04 U2OS 96 6468 MetaphaseAlignment +0.06392051081889777 4.5510109384881127e-10 BR00118039 KDR final orf O02 U2OS 96 5406 MetaphaseAlignment +0.06400394397990586 6.295733145910021e-10 BR00118039 HTR2C final orf M06 U2OS 96 5322 MetaphaseAlignment +0.07787114845938375 7.782889818562917e-10 BR00118039 AKR1B1 final orf L17 U2OS 96 3570 MetaphaseAlignment +0.06887872242725217 8.499060494686169e-10 BR00118039 GRIN2A final orf A05 U2OS 96 4524 MetaphaseAlignment +0.08817995832424246 9.071349160556204e-10 BR00118039 CATSPER4 final orf P07 U2OS 96 2754 MetaphaseAlignment +0.05630753400417067 1.157373865016857e-09 BR00118039 TBXAS1 final orf J24 U2OS 96 6684 MetaphaseAlignment +0.06381269074234197 1.1801392796642785e-09 BR00118040 GHSR final orf A17 U2OS 96 5196 MetaphaseAlignment +0.07347761753506817 1.2970630372335378e-09 BR00118040 KCNMA1 final orf G01 U2OS 96 3900 MetaphaseAlignment +0.05916958783771526 1.468180765964537e-09 BR00118039 TUBB3 final orf G06 U2OS 96 5976 MetaphaseAlignment +0.06311671849313712 1.7091990842936717e-09 BR00118039 P2RY12 final orf B24 U2OS 96 5220 MetaphaseAlignment +0.05774995328562972 2.079262719378621e-09 BR00118040 PTGIS final orf F16 U2OS 96 6180 MetaphaseAlignment +0.06234534469634834 2.466662181109596e-09 BR00118040 TNF final orf C13 U2OS 96 5256 MetaphaseAlignment +0.06428277367269161 3.2810746040727527e-09 BR00118039 KCNN4 final orf A06 U2OS 96 4878 MetaphaseAlignment +0.06351587628433435 4.991284529954152e-09 BR00118040 CSK final orf B04 U2OS 96 4902 MetaphaseAlignment +0.06412673437771729 6.448341819905058e-09 BR00118039 NAMPT final orf D13 U2OS 96 4746 MetaphaseAlignment +0.06285890671626732 7.125723500533388e-09 BR00118039 TGFBR1 final orf O14 U2OS 96 4908 MetaphaseAlignment +0.05967368862887034 7.241592275639892e-09 BR00118039 GPR119 final orf N23 U2OS 96 5436 MetaphaseAlignment +0.060382025712415834 7.67592352276892e-09 BR00118039 PLA2G1B final orf E06 U2OS 96 5304 MetaphaseAlignment +0.05419333711446011 8.794390684614023e-09 BR00118039 HDAC6 final orf E20 U2OS 96 6534 MetaphaseAlignment +0.05733136044166487 1.0316452571022803e-08 BR00118040 CCR1 final orf F24 U2OS 96 5796 MetaphaseAlignment +0.060796775355332996 1.0360874818566336e-08 BR00118040 IGF1R final orf H05 U2OS 96 5136 MetaphaseAlignment +0.05518435008461195 1.051634488888853e-08 BR00118040 HTR2C final orf G21 U2OS 96 6228 MetaphaseAlignment 0.8329991980753809 4.3892791266274795e-62 BR00118040 GRIN2A final orf A05 U2OS 96 174 OutOfFocus 0.17073071722462188 2.003103664699414e-55 BR00118040 CHRM3 final orf A11 U2OS 96 4314 OutOfFocus 0.1928424325260339 1.718429944397212e-49 BR00118039 DYRK1B final orf G13 U2OS 96 3012 OutOfFocus @@ -1769,6 +17609,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.11947983067395654 1.0771310318338408e-28 BR00118039 CDK4 final orf P20 U2OS 96 4542 OutOfFocus 0.10764147441468636 1.2178041102067107e-26 BR00118040 GHSR final orf A17 U2OS 96 5196 OutOfFocus 0.11510371480400662 4.900238818117287e-24 BR00118039 P3H1 final orf P24 U2OS 96 4092 OutOfFocus +0.10961744940498087 2.199816129782787e-23 BR00118040 SCNN1G final orf A04 U2OS 96 4386 OutOfFocus +0.11601945688077978 1.0406686913268157e-22 BR00118040 OPRL1 final orf A23 U2OS 96 3798 OutOfFocus +0.10356258247727686 2.271419448699986e-22 BR00118040 KCNH7 final orf A22 U2OS 96 4692 OutOfFocus +0.12000634712842026 2.851172080462932e-22 BR00118040 OPRM1 final orf A08 U2OS 96 3480 OutOfFocus +0.10243811324494728 4.373249880482081e-21 BR00118039 GRIN2A final orf A05 U2OS 96 4524 OutOfFocus +0.08439201451905626 6.714080851135143e-21 BR00118039 GABRB2 final orf C19 U2OS 96 6612 OutOfFocus +0.1545746908458773 9.160063394953818e-21 BR00118039 DYRK1B final orf M12 U2OS 96 1950 OutOfFocus +0.11227139645952725 1.867361200638174e-20 BR00118039 KCNN1 final orf A01 U2OS 96 3642 OutOfFocus +0.1603658489502498 3.1044787471450423e-20 BR00118039 KCNMA1 final orf G01 U2OS 96 1764 OutOfFocus +0.08068576074877627 4.4179900470541636e-20 BR00118039 KCNH7 final orf A22 U2OS 96 6924 OutOfFocus +0.10587607970571075 5.11748328356126e-20 BR00118040 CHRM3 final orf A10 U2OS 96 4002 OutOfFocus +0.09816013552710359 8.161822044442397e-20 BR00118040 HIF1A final orf A12 U2OS 96 4614 OutOfFocus +0.146875 1.7889252735613537e-18 BR00118039 SLCO2B1 final orf A02 U2OS 96 1920 OutOfFocus +0.08833878314812225 3.976569459523828e-18 BR00118040 ADA final orf P04 U2OS 96 5208 OutOfFocus +0.12239252951581718 4.241952262256082e-18 BR00118040 DYRK1B final orf M12 U2OS 96 2700 OutOfFocus +0.09896442020516816 7.448922504761986e-18 BR00118040 FOXM1 final orf P15 U2OS 96 4080 OutOfFocus +0.08324632696905002 1.3466627689278361e-17 BR00118040 CDK2 final orf L03 U2OS 96 5682 OutOfFocus +0.09046402724563644 3.8243091749170194e-17 BR00118040 CACNG1 final orf A16 U2OS 96 4698 OutOfFocus +0.10642686922847781 5.180760109982797e-17 BR00118040 SLC7A11 final orf A03 U2OS 96 3360 OutOfFocus +0.08196174183208065 6.885834322684106e-17 BR00118039 AKT1 final orf J16 U2OS 96 5628 OutOfFocus +0.07260384618875185 1.7176508802434093e-16 BR00118039 PIK3CG final orf G18 U2OS 96 6996 OutOfFocus +0.08843980877879183 4.465413759739366e-16 BR00118039 AKR1C1 final orf I01 U2OS 96 4602 OutOfFocus +0.07811238706453359 6.111916896637145e-16 BR00118039 SLC7A11 final orf G24 U2OS 96 5844 OutOfFocus +0.09258024043234933 6.527151624269774e-16 BR00118040 CACNB4 final orf M01 U2OS 96 4152 OutOfFocus +0.0930004894762604 8.563810014387194e-16 BR00118039 SIRT2 final orf A07 U2OS 96 4086 OutOfFocus +0.0763203930105158 9.239773235234208e-16 BR00118039 CDC25A final orf M04 U2OS 96 6042 OutOfFocus +0.07815850732829042 1.1095464183339032e-15 BR00118040 ICAM1 final orf I15 U2OS 96 5730 OutOfFocus +0.08541966396053849 1.7375445977238263e-15 BR00118039 CYP2A6 final orf A20 U2OS 96 4734 OutOfFocus +0.07392360087391045 1.9293923687771425e-15 BR00118039 FFAR4 final orf C17 U2OS 96 6300 OutOfFocus +0.0876988347296683 2.4184448431617267e-15 BR00118039 LCK final orf H01 U2OS 96 4452 OutOfFocus +0.08916255113503889 2.8230758756851956e-15 BR00118039 ADA final orf P03 U2OS 96 4290 OutOfFocus +0.09684100306370626 3.4531943596622776e-15 BR00118040 ELANE final orf D19 U2OS 96 3606 OutOfFocus +0.10266810738924445 4.673981532901796e-15 BR00118040 LYN final orf C20 U2OS 96 3180 OutOfFocus +0.08599973951143988 5.457378120379186e-15 BR00118040 SIRT2 final orf G02 U2OS 96 4518 OutOfFocus +0.07476431205487008 1.2029084720480162e-14 BR00118039 DCK final orf D05 U2OS 96 5838 OutOfFocus +0.07811120787136427 1.4198235911008807e-14 BR00118039 HTR2C final orf M06 U2OS 96 5322 OutOfFocus +0.06965732947164176 1.523895747530128e-14 BR00118039 TBXAS1 final orf J24 U2OS 96 6684 OutOfFocus +0.10575872377436214 1.5279671360679353e-14 BR00118040 GJB4 final orf P08 U2OS 96 2898 OutOfFocus +0.08791534838544675 3.263836103725216e-14 BR00118040 AURKB final orf H10 U2OS 96 4086 OutOfFocus +0.09467120181405896 3.547540880406747e-14 BR00118040 IMPDH1 final orf L13 U2OS 96 3528 OutOfFocus +0.07562076749435666 1.2226643250185928e-13 BR00118040 CACNB4 final orf A18 U2OS 96 5316 OutOfFocus +0.07317506081423952 1.5102747309753336e-13 BR00118039 ANXA1 final orf D23 U2OS 96 5628 OutOfFocus +0.08782922642886737 1.5465964917081406e-13 BR00118040 KCNMA1 final orf G01 U2OS 96 3900 OutOfFocus +0.0836147764569308 1.593764231443959e-13 BR00118039 BTK final orf P10 U2OS 96 4290 OutOfFocus +0.06399989170457007 1.964257416427337e-13 BR00118040 MAPK14 final orf G22 U2OS 96 7296 OutOfFocus +0.06513652942529491 2.1593647160701738e-13 BR00118039 CHRM2 final orf B08 U2OS 96 7020 OutOfFocus +0.07985885953661451 2.179114737346987e-13 BR00118040 UGT1A9 final orf E24 U2OS 96 4668 OutOfFocus +0.07430584321023034 2.430046046320757e-13 BR00118039 ASIC1 final orf L21 U2OS 96 5364 OutOfFocus +0.11747580308219634 3.298067780211025e-13 BR00118040 PTK2B final orf J18 U2OS 96 2124 OutOfFocus +0.08398021262609935 4.946650892119741e-13 BR00118040 SIRT2 final orf A07 U2OS 96 4092 OutOfFocus +0.066802655787537 5.123629602623949e-13 BR00118039 PDE7A final orf F20 U2OS 96 6480 OutOfFocus +0.0712265818310357 6.690334461067574e-13 BR00118040 S1PR1 final orf P22 U2OS 96 5658 OutOfFocus +0.08526617191608718 6.809514884739557e-13 BR00118040 DDR2 final orf A19 U2OS 96 3924 OutOfFocus +0.06838635166750649 7.911257620396329e-13 BR00118039 TUBB final orf M16 U2OS 96 6078 OutOfFocus +0.0663765010587221 8.450109662962163e-13 BR00118039 AKT1 final orf F15 U2OS 96 6450 OutOfFocus +0.08308966861598441 9.620994738708397e-13 BR00118039 CACNB4 final orf M01 U2OS 96 4104 OutOfFocus +0.08299326668026934 1.317471038673563e-12 BR00118039 HTR3A final orf H24 U2OS 96 4056 OutOfFocus +0.0754840587782416 1.5005317967614056e-12 BR00118039 KCNN4 final orf A06 U2OS 96 4878 OutOfFocus +0.08324575978203239 2.1038938018057777e-12 BR00118039 HSP90AB1 final orf P01 U2OS 96 3966 OutOfFocus +0.08521660966970622 2.4572296515934752e-12 BR00118039 KRAS final orf F08 U2OS 96 3762 OutOfFocus +0.07442409451550076 2.886024634235759e-12 BR00118039 CATSPER4 final orf D24 U2OS 96 4902 OutOfFocus +0.07934776933910151 3.2759636420922327e-12 BR00118040 MMP2 final orf J15 U2OS 96 4302 OutOfFocus +0.07603832330168454 3.655943199847714e-12 BR00118039 CHRM3 final orf A11 U2OS 96 4662 OutOfFocus +0.08101512933138116 4.059002406064441e-12 BR00118040 COMT final orf P09 U2OS 96 4098 OutOfFocus +0.07031348144943572 5.482167261565163e-12 BR00118040 S1PR1 final orf L01 U2OS 96 5370 OutOfFocus +0.07262905162064826 6.953459074399047e-12 BR00118039 SLC7A11 final orf A03 U2OS 96 4998 OutOfFocus +0.07850337657417808 7.015898081055448e-12 BR00118040 HTR2C final orf M06 U2OS 96 4272 OutOfFocus +0.07571801566579635 7.0423175785117186e-12 BR00118040 KDR final orf O02 U2OS 96 4596 OutOfFocus +0.07857672571558437 7.194003617827142e-12 BR00118040 P2RY12 final orf B01 U2OS 96 4248 OutOfFocus +0.08163839771926452 1.1171635848909254e-11 BR00118040 CATSPER4 final orf P07 U2OS 96 3870 OutOfFocus +0.06387616490285895 1.1697623077682048e-11 BR00118039 HTR3A final orf J23 U2OS 96 6330 OutOfFocus +0.07143675924356149 1.518712432169352e-11 BR00118039 LPAR1 final orf B05 U2OS 96 4992 OutOfFocus +0.06488801054018445 1.5524676001710383e-11 BR00118040 CLK1 final orf D08 U2OS 96 6072 OutOfFocus +0.066411209924595 1.5753207886230833e-11 BR00118039 PTGIR final orf C07 U2OS 96 5778 OutOfFocus +0.07426116313789359 1.704589141679035e-11 BR00118040 TUBB3 final orf K05 U2OS 96 4608 OutOfFocus +0.07556566074135318 1.91890003601964e-11 BR00118040 PTPN2 final orf I02 U2OS 96 4428 OutOfFocus +0.06733607426629339 2.298237182127291e-11 BR00118039 SSTR2 final orf J01 U2OS 96 5532 OutOfFocus +0.06495042296544648 2.5979396680199165e-11 BR00118039 S1PR1 final orf L01 U2OS 96 5934 OutOfFocus +0.061372835980122074 3.851260076841342e-11 BR00118039 HDAC6 final orf E20 U2OS 96 6534 OutOfFocus +0.07185546821040194 4.055299860845234e-11 BR00118040 AGER final orf H18 U2OS 96 4752 OutOfFocus +0.058304891922639365 8.204785565176339e-11 BR00118039 CDC25A final orf I19 U2OS 96 7032 OutOfFocus +0.063710499490316 8.297800305879923e-11 BR00118040 CYP3A4 final orf K22 U2OS 96 5886 OutOfFocus +0.09056960943570476 8.76540603882918e-11 BR00118040 AGER final orf H09 U2OS 96 2892 OutOfFocus +0.06890517538170841 1.4531432967406814e-10 BR00118040 HPGDS final orf O24 U2OS 96 4896 OutOfFocus +0.06284120794570475 1.5006941395863106e-10 BR00118040 CSK final orf P05 U2OS 96 5892 OutOfFocus +0.06687021314794343 1.7263593666903318e-10 BR00118039 DDR2 final orf M02 U2OS 96 5154 OutOfFocus +0.05998297476265813 1.7749759934201018e-10 BR00118039 P3H1 final orf F23 U2OS 96 6408 OutOfFocus +0.05938169574533211 1.9485909739496303e-10 BR00118040 TUBB final orf E19 U2OS 96 6534 OutOfFocus +0.05680666053508091 2.33361490959545e-10 BR00118039 TUBB4B final orf E04 U2OS 96 7068 OutOfFocus +0.07415976688018186 2.452167495889461e-10 BR00118040 CCR1 final orf P17 U2OS 96 4134 OutOfFocus 0.1804393807942984 1.0320768441453884e-58 BR00118039 P3H1 final orf P24 U2OS 96 4092 Polylobed 0.1585348644075205 4.029463330430015e-42 BR00118040 KRAS final orf F08 U2OS 96 3798 Polylobed 0.1346367161814259 1.486730658480826e-34 BR00118040 CHRM3 final orf A11 U2OS 96 4314 Polylobed @@ -1779,6 +17709,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.11529445141009609 2.5309255258239263e-25 BR00118039 ADA final orf P03 U2OS 96 4290 Polylobed 0.09352740232522067 5.469883023306551e-25 BR00118039 AKT1 final orf F15 U2OS 96 6450 Polylobed 0.11355849241311797 2.3493015721290527e-23 BR00118039 LYN final orf M05 U2OS 96 4086 Polylobed +0.09103131197505217 9.319229098746123e-23 BR00118040 PTGIS final orf F16 U2OS 96 6180 Polylobed +0.11020299200147854 7.99295470286074e-22 BR00118040 SSTR2 final orf J01 U2OS 96 4044 Polylobed +0.11377790113679864 1.213946687728218e-21 BR00118039 KRAS final orf F08 U2OS 96 3762 Polylobed +0.10968134662393002 3.1639087226537674e-21 BR00118039 HSP90AB1 final orf P01 U2OS 96 3966 Polylobed +0.111638458742407 3.2726348513416606e-20 BR00118039 KCNN1 final orf A01 U2OS 96 3642 Polylobed +0.09236267870579383 3.7975533200085195e-20 BR00118040 CACNB4 final orf A18 U2OS 96 5316 Polylobed +0.10634877968016518 9.495042093678974e-20 BR00118040 DDR2 final orf A19 U2OS 96 3924 Polylobed +0.09571712133550489 7.912266342527446e-19 BR00118040 TUBB3 final orf K05 U2OS 96 4608 Polylobed +0.08595496370867116 1.5656077311969586e-18 BR00118039 AKT1 final orf J16 U2OS 96 5628 Polylobed +0.07898392179690479 5.408904757953228e-18 BR00118039 KCNJ1 final orf E22 U2OS 96 6468 Polylobed +0.08903561424569828 1.1825935215995596e-17 BR00118039 SLC7A11 final orf A03 U2OS 96 4998 Polylobed +0.0836574104625523 1.4157527577243584e-17 BR00118039 ANXA1 final orf D23 U2OS 96 5628 Polylobed +0.08141094706180452 3.191172624767317e-17 BR00118039 TUBB final orf E19 U2OS 96 5814 Polylobed +0.08534542541437423 4.044188579075998e-17 BR00118040 TNF final orf C13 U2OS 96 5256 Polylobed +0.1010809953090754 6.136655748894453e-16 BR00118040 OPRM1 final orf A08 U2OS 96 3480 Polylobed +0.08232945939441982 1.1070689337626932e-15 BR00118039 TNF final orf C13 U2OS 96 5166 Polylobed +0.08864057802213972 1.9659052131740675e-15 BR00118040 SCNN1G final orf A04 U2OS 96 4386 Polylobed +0.10431057621594166 2.110696754917518e-15 BR00118040 PRKCE final orf J19 U2OS 96 3156 Polylobed +0.08574212302628094 5.563540370905338e-15 BR00118039 CDK4 final orf P20 U2OS 96 4542 Polylobed +0.08386547467007237 8.6159216985797e-15 BR00118040 CACNG1 final orf A16 U2OS 96 4698 Polylobed +0.11624224505322538 1.2449647789671686e-14 BR00118040 LYN final orf M05 U2OS 96 2412 Polylobed +0.07170356111645813 2.3464470501203794e-14 BR00118040 P3H1 final orf P24 U2OS 96 6234 Polylobed +0.09156722801890739 2.568723924333292e-14 BR00118040 OPRL1 final orf A23 U2OS 96 3798 Polylobed +0.07628041029909442 2.871102045265543e-14 BR00118039 HCK final orf O01 U2OS 96 5454 Polylobed +0.07744833702685341 5.557084212712113e-14 BR00118040 GHSR final orf A17 U2OS 96 5196 Polylobed +0.08072809620456958 6.841424141619744e-14 BR00118039 CYP2A6 final orf A20 U2OS 96 4734 Polylobed +0.0698948434747768 8.200104997891818e-14 BR00118039 FFAR4 final orf C17 U2OS 96 6300 Polylobed +0.08085633616185216 8.414046202328027e-14 BR00118040 KCNH7 final orf A22 U2OS 96 4692 Polylobed +0.4113873295910184 9.285996674835767e-14 BR00118040 GRIN2A final orf A05 U2OS 96 174 Polylobed +0.0800377752274035 9.672723360274972e-14 BR00118040 NAMPT final orf D13 U2OS 96 4776 Polylobed +0.08730388617238494 1.0668342602542359e-13 BR00118040 CHRM3 final orf A10 U2OS 96 4002 Polylobed +0.10480283066298604 1.2940874023745256e-13 BR00118039 CATSPER4 final orf P07 U2OS 96 2754 Polylobed +0.07202113479418384 1.6515366967866367e-13 BR00118040 EDNRB final orf K11 U2OS 96 5784 Polylobed +0.08527131782945736 1.7832135691805757e-13 BR00118040 AKR1C1 final orf A24 U2OS 96 4128 Polylobed +0.06399673308786369 1.9700176728406637e-13 BR00118040 MAPK14 final orf G22 U2OS 96 7296 Polylobed +0.09131652661064425 2.2710465899041544e-13 BR00118039 AKR1B1 final orf L17 U2OS 96 3570 Polylobed +0.08066207607030369 3.2595546964530065e-13 BR00118040 SIRT2 final orf G02 U2OS 96 4518 Polylobed +0.07272613579026727 3.741229579699294e-13 BR00118039 SSTR2 final orf J01 U2OS 96 5532 Polylobed +0.06478503573882674 4.993328218149092e-13 BR00118040 ADORA2A final orf O23 U2OS 96 6888 Polylobed +0.08866995073891626 6.448647589041421e-13 BR00118040 KCNN4 final orf A06 U2OS 96 3654 Polylobed +0.0644334185640651 7.250875192093686e-13 BR00118039 FGF1 final orf F22 U2OS 96 6876 Polylobed +0.1203125 1.6029242286634909e-12 BR00118039 SLCO2B1 final orf A02 U2OS 96 1920 Polylobed +0.07071744671598097 2.5148622510676835e-12 BR00118039 HPGDS final orf O24 U2OS 96 5460 Polylobed +0.07162229426179294 2.64176839302461e-12 BR00118040 RGS4 final orf D20 U2OS 96 5310 Polylobed +0.06510665393186883 5.359261177792154e-12 BR00118040 TGM2 final orf B07 U2OS 96 6282 Polylobed +0.0734614938093029 5.695228920848017e-12 BR00118039 TGFBR1 final orf O14 U2OS 96 4908 Polylobed +0.08229813664596274 8.390799653830138e-12 BR00118039 ADA final orf P04 U2OS 96 3864 Polylobed +0.06334768168384468 9.653133422737232e-12 BR00118040 CACNG1 final orf E23 U2OS 96 6480 Polylobed +0.06521739130434782 1.1963657062108203e-11 BR00118040 CLK1 final orf D08 U2OS 96 6072 Polylobed +0.07530417770417161 1.248135010805088e-11 BR00118039 GRIN2A final orf A05 U2OS 96 4524 Polylobed +0.0687574236405249 1.299826312083545e-11 BR00118039 GPR119 final orf N23 U2OS 96 5436 Polylobed +0.06537291881261031 1.432891247485276e-11 BR00118039 TUBB3 final orf G06 U2OS 96 5976 Polylobed +0.07657038055937643 1.529539275112194e-11 BR00118040 CYP1A2 final orf N12 U2OS 96 4362 Polylobed +0.07905041605482134 1.591653437368592e-11 BR00118039 SIRT2 final orf A07 U2OS 96 4086 Polylobed +0.07396345991197055 2.0360871567691773e-11 BR00118040 HIF1A final orf A12 U2OS 96 4614 Polylobed +0.06843211622605458 2.284130984265308e-11 BR00118040 GHSR final orf C24 U2OS 96 5364 Polylobed +0.069188967988424 2.5190522901812957e-11 BR00118040 EZH2 final orf D04 U2OS 96 5226 Polylobed +0.06022163896179644 3.1168024367296637e-11 BR00118039 CDK7 final orf M21 U2OS 96 6858 Polylobed +0.06527777777777778 4.3137715274243523e-11 BR00118039 SIRT2 final orf G02 U2OS 96 5760 Polylobed +0.07181812943773214 6.815792732310167e-11 BR00118039 PAK1 final orf L09 U2OS 96 4656 Polylobed +0.06407814893547484 7.252794146018979e-11 BR00118039 BAX final orf G12 U2OS 96 5844 Polylobed +0.06427276544494982 7.895062398672126e-11 BR00118039 BRD4 final orf F14 U2OS 96 5778 Polylobed +0.06884873949579833 9.128153998894104e-11 BR00118040 BRD4 final orf F14 U2OS 96 4998 Polylobed +0.06146596353192465 1.0935276916302796e-10 BR00118040 HTR2C final orf G21 U2OS 96 6228 Polylobed +0.07100785520441696 1.0987439844853212e-10 BR00118039 CACNB4 final orf A18 U2OS 96 4668 Polylobed +0.11475441481927617 1.353838381132516e-10 BR00118040 KRAS final orf D17 U2OS 96 1764 Polylobed +0.06296323741535238 1.577114985816744e-10 BR00118039 DCK final orf D05 U2OS 96 5838 Polylobed +0.07068329564147925 1.80434738761967e-10 BR00118040 MMP2 final orf F06 U2OS 96 4614 Polylobed +0.058026741561890374 2.525234184940597e-10 BR00118039 DHH final orf E08 U2OS 96 6744 Polylobed +0.0659025393251576 3.360707102570313e-10 BR00118039 DDR2 final orf M02 U2OS 96 5154 Polylobed +0.06061227078088485 3.845484651928481e-10 BR00118039 TUBB final orf M16 U2OS 96 6078 Polylobed +0.06346589635381432 4.840822703362245e-10 BR00118040 CACNA2D3 final orf P19 U2OS 96 5478 Polylobed +0.05911143435442334 5.158517824714214e-10 BR00118039 GPR55 final orf F13 U2OS 96 6288 Polylobed +0.06227970031613568 9.621903294212182e-10 BR00118040 USP1 final orf E12 U2OS 96 5502 Polylobed +0.08222643896268185 1.0169155916487156e-09 BR00118040 ABL1 final orf C01 U2OS 96 3162 Polylobed +0.055417089845192384 1.0557838508066912e-09 BR00118039 KCNH7 final orf A22 U2OS 96 6924 Polylobed +0.06316083148715053 1.101644290815272e-09 BR00118039 HTR2C final orf M06 U2OS 96 5322 Polylobed +0.059976397059798535 1.5353869666013696e-09 BR00118039 PARP3 final orf H21 U2OS 96 5826 Polylobed +0.06191982815814743 1.942808939369105e-09 BR00118039 HTR2C final orf G21 U2OS 96 5394 Polylobed +0.058753180126574295 2.0767291118937275e-09 BR00118040 P2RY12 final orf B24 U2OS 96 5970 Polylobed +0.07097440845400568 2.150515663954764e-09 BR00118040 SIRT2 final orf A07 U2OS 96 4092 Polylobed +0.06175675647730539 2.2023113358785947e-09 BR00118040 IL1B final orf E15 U2OS 96 5388 Polylobed +0.06205309010694856 3.5819513417507416e-09 BR00118040 ADA final orf P04 U2OS 96 5208 Polylobed +0.05844376486578321 3.6766710771546407e-09 BR00118040 CYP3A4 final orf K22 U2OS 96 5886 Polylobed +0.062090156230240515 4.724715068236519e-09 BR00118040 CDK4 final orf B21 U2OS 96 5130 Polylobed +0.05696728949999919 4.7992147067283105e-09 BR00118039 ATP5F1D final orf G14 U2OS 96 6084 Polylobed +0.06799745605981285 5.014006416711013e-09 BR00118040 HTR2C final orf M06 U2OS 96 4272 Polylobed +0.06941198112799203 5.431584931559727e-09 BR00118040 FOXM1 final orf P15 U2OS 96 4080 Polylobed +0.057166666666666664 6.044742937901822e-09 BR00118040 PRKCB final orf K14 U2OS 96 6000 Polylobed +0.05710920504109824 6.244583538569094e-09 BR00118039 CACNG1 final orf E23 U2OS 96 5988 Polylobed 0.13879620504173742 3.387414569003114e-27 BR00118040 LYN final orf C20 U2OS 96 3180 Prometaphase 0.08770314862111644 6.50423986138424e-25 BR00118040 P3H1 final orf F23 U2OS 96 7308 Prometaphase 0.08998767198344089 1.118778495155249e-24 BR00118039 FGF1 final orf F22 U2OS 96 6876 Prometaphase @@ -1789,6 +17809,96 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.08081418466074843 2.7646848255937395e-17 BR00118040 PAK4 final orf G10 U2OS 96 5928 Prometaphase 0.08508482770173213 5.1976979282076133e-17 BR00118040 TNF final orf C13 U2OS 96 5256 Prometaphase 0.07609044260442509 9.238267969266202e-16 BR00118039 TUBB final orf M16 U2OS 96 6078 Prometaphase +0.09903940239060999 1.049533308490166e-14 BR00118040 DYRK1B final orf G13 U2OS 96 3336 Prometaphase +0.08301404853128991 1.682076413239528e-14 BR00118040 TNF final orf C18 U2OS 96 4698 Prometaphase +0.07775746107866274 1.699916977276691e-14 BR00118040 HSP90AB1 final orf P01 U2OS 96 5334 Prometaphase +0.07154315046519089 2.7084679927184266e-14 BR00118040 P3H1 final orf P24 U2OS 96 6234 Prometaphase +0.07735771308651714 6.219117153982506e-14 BR00118039 EDNRB final orf M08 U2OS 96 5178 Prometaphase +0.12379597803326617 1.8422975179961576e-13 BR00118039 DYRK1B final orf M12 U2OS 96 1950 Prometaphase +0.07675438596491228 2.8581814568929014e-13 BR00118040 TUBB3 final orf G06 U2OS 96 5016 Prometaphase +0.06755202548239249 5.103045149735732e-13 BR00118040 PDE3A final orf O22 U2OS 96 6342 Prometaphase +0.07846515336590662 8.765270370089151e-13 BR00118040 TUBB3 final orf K05 U2OS 96 4608 Prometaphase +0.08022594889432316 9.987756086081152e-13 BR00118040 SCNN1G final orf A04 U2OS 96 4386 Prometaphase +0.07065110960185242 1.0941778793805745e-12 BR00118040 RPL3 final orf G09 U2OS 96 5628 Prometaphase +0.0680171277997365 1.2382671922190284e-12 BR00118040 CLK1 final orf D08 U2OS 96 6072 Prometaphase +0.07016829255157359 1.7178156838892021e-12 BR00118039 AKT1 final orf J16 U2OS 96 5628 Prometaphase +0.08061432373005739 3.272065983861112e-12 BR00118040 ABL1 final orf M24 U2OS 96 4152 Prometaphase +0.06832007735946648 4.634346323368926e-12 BR00118039 CCND1 final orf P16 U2OS 96 5718 Prometaphase +0.08569051580698835 5.850691995868711e-12 BR00118040 ELANE final orf D19 U2OS 96 3606 Prometaphase +0.06501368128726619 2.3182252787510338e-11 BR00118039 BAX final orf K17 U2OS 96 5940 Prometaphase +0.09598008967871982 2.8621672054069096e-11 BR00118040 DYRK1B final orf M12 U2OS 96 2700 Prometaphase +0.3718925421010425 2.931098342650204e-11 BR00118040 GRIN2A final orf A05 U2OS 96 174 Prometaphase +0.07860591074120525 3.2208442073700174e-11 BR00118040 CHRM3 final orf A10 U2OS 96 4002 Prometaphase +0.06930283448261067 3.350277385964842e-11 BR00118039 DDR2 final orf M02 U2OS 96 5154 Prometaphase +0.06400808185057445 4.1961827420298545e-11 BR00118039 TUBB3 final orf G06 U2OS 96 5976 Prometaphase +0.08475053918642644 4.6706597262643253e-11 BR00118040 LPAR1 final orf B20 U2OS 96 3396 Prometaphase +0.0653922793412113 6.616062296470487e-11 BR00118039 ANXA1 final orf D23 U2OS 96 5628 Prometaphase +0.0644403543706597 8.971398681956632e-11 BR00118039 PPARD final orf M07 U2OS 96 5712 Prometaphase +0.06013518918486521 1.264517865675496e-10 BR00118039 PDE7A final orf F20 U2OS 96 6480 Prometaphase +0.07313159101329665 1.4504331863914122e-10 BR00118040 CYP1A2 final orf N12 U2OS 96 4362 Prometaphase +0.06066411238825032 1.923831194890648e-10 BR00118040 ERBB2 final orf E21 U2OS 96 6264 Prometaphase +0.07123834886817576 2.30400922512123e-10 BR00118040 MAPK8 final orf I14 U2OS 96 4506 Prometaphase +0.07124841821792641 2.5336625444326055e-10 BR00118040 BRAF final orf C05 U2OS 96 4470 Prometaphase +0.07983193277310924 2.575039499030454e-10 BR00118039 AKR1B1 final orf L17 U2OS 96 3570 Prometaphase +0.06335461150984656 3.904090315636449e-10 BR00118040 KCNH7 final orf O07 U2OS 96 5562 Prometaphase +0.07394015897844003 4.6225784918162364e-10 BR00118039 PNLIP final orf L22 U2OS 96 4050 Prometaphase +0.07672425797094636 8.848664342923138e-10 BR00118039 KCNN1 final orf A01 U2OS 96 3642 Prometaphase +0.06398806811488218 1.0980305185781334e-09 BR00118040 CASP3 final orf N05 U2OS 96 5196 Prometaphase +0.06167131082055379 1.2373971689992007e-09 BR00118040 TBXAS1 final orf J24 U2OS 96 5550 Prometaphase +0.06448412698412699 1.5629994329130164e-09 BR00118040 F10 final orf C09 U2OS 96 5040 Prometaphase +0.05984126651654968 1.6120000227971022e-09 BR00118039 DCK final orf D05 U2OS 96 5838 Prometaphase +0.054738554084590385 1.6167477135998344e-09 BR00118039 FPR1 final orf D21 U2OS 96 6954 Prometaphase +0.05308213305898491 2.239285129811174e-09 BR00118040 MAPK14 final orf G22 U2OS 96 7296 Prometaphase +0.056032838410846435 2.3323262718547913e-09 BR00118039 HDAC6 final orf E20 U2OS 96 6534 Prometaphase +0.07314524555903866 2.509602619177653e-09 BR00118039 ABL1 final orf C01 U2OS 96 3828 Prometaphase +0.06121330181792615 3.152908384927009e-09 BR00118040 IL1B final orf E15 U2OS 96 5388 Prometaphase +0.05383243907793853 3.5226993560839085e-09 BR00118039 KCNH7 final orf A22 U2OS 96 6924 Prometaphase +0.06653718679999213 3.677406493617693e-09 BR00118040 SIRT2 final orf G02 U2OS 96 4518 Prometaphase +0.08107847310162139 4.3966191593939525e-09 BR00118039 DYRK1B final orf G13 U2OS 96 3012 Prometaphase +0.07339022978091479 4.603001533311661e-09 BR00118039 IMPDH1 final orf N20 U2OS 96 3684 Prometaphase +0.053902953925240187 4.6161249394023364e-09 BR00118039 HCK final orf O20 U2OS 96 6834 Prometaphase +0.05576164677627529 5.863509245667074e-09 BR00118039 GPR55 final orf F13 U2OS 96 6288 Prometaphase +0.057881260540614245 6.04152092735249e-09 BR00118039 RET final orf K10 U2OS 96 5844 Prometaphase +0.05907206424347501 1.4360607479290851e-08 BR00118039 PTGIR final orf E16 U2OS 96 5358 Prometaphase +0.05328911640456632 1.9809690395127516e-08 BR00118040 CACNG1 final orf E23 U2OS 96 6480 Prometaphase +0.06340819022457067 2.3210659800180192e-08 BR00118040 PLA2G1B final orf E06 U2OS 96 4542 Prometaphase +0.04857881136950904 2.3214341730154366e-08 BR00118039 ERBB2 final orf I20 U2OS 96 7740 Prometaphase +0.06783923574560007 2.4936166677540148e-08 BR00118040 CCND1 final orf B11 U2OS 96 3942 Prometaphase +0.10095593288393677 2.7918582557806754e-08 BR00118040 KRAS final orf D17 U2OS 96 1764 Prometaphase +0.056015554295285035 2.915040280195422e-08 BR00118040 GRIN2A final orf I24 U2OS 96 5730 Prometaphase +0.10899222259896583 2.9777353882260997e-08 BR00118040 PTK2B final orf N19 U2OS 96 1506 Prometaphase +0.06107599963392428 3.296176104050572e-08 BR00118040 NAMPT final orf D13 U2OS 96 4776 Prometaphase +0.05638658813601447 3.5643330595851696e-08 BR00118040 CDK2 final orf J04 U2OS 96 5580 Prometaphase +0.06396357126127163 4.001861640477854e-08 BR00118040 CHRM3 final orf A11 U2OS 96 4314 Prometaphase +0.057979056918702705 4.048412268911522e-08 BR00118039 TNNC1 final orf G07 U2OS 96 5256 Prometaphase +0.055085974303990724 5.05744045346059e-08 BR00118039 AVPR1A final orf H22 U2OS 96 5748 Prometaphase +0.056754145668744455 6.08809349708342e-08 BR00118039 ASIC1 final orf L21 U2OS 96 5364 Prometaphase +0.04947412494582306 6.966531368639883e-08 BR00118039 PIK3CG final orf G18 U2OS 96 6996 Prometaphase +0.06120700697905707 7.140752949861665e-08 BR00118039 CHEK2 final orf H06 U2OS 96 4566 Prometaphase +0.05112320580018388 7.703541869752877e-08 BR00118039 CHRM2 final orf B03 U2OS 96 6522 Prometaphase +0.06394391467634815 8.323580291542354e-08 BR00118040 CCR1 final orf P17 U2OS 96 4134 Prometaphase +0.055659804512896746 9.005854078096848e-08 BR00118040 PIK3CG final orf G18 U2OS 96 5436 Prometaphase +0.05118672376420136 1.1095901341765953e-07 BR00118040 RET final orf K10 U2OS 96 6342 Prometaphase +0.06547464603754244 1.1449973822581712e-07 BR00118040 CYP2A6 final orf A15 U2OS 96 3870 Prometaphase +0.061234669973818386 1.1590713652108473e-07 BR00118040 PTPN2 final orf I02 U2OS 96 4428 Prometaphase +0.057623049219687875 1.2315472881983322e-07 BR00118039 SLC7A11 final orf A03 U2OS 96 4998 Prometaphase +0.07222228240394696 1.2988393355352967e-07 BR00118040 PRKCE final orf J19 U2OS 96 3156 Prometaphase +0.06499654743819915 1.3299988919185061e-07 BR00118040 KCNMA1 final orf G01 U2OS 96 3900 Prometaphase +0.05219689461513049 1.3646393855641286e-07 BR00118039 CYP3A4 final orf K09 U2OS 96 6054 Prometaphase +0.05383488410124303 1.406518543830384e-07 BR00118039 DDR2 final orf A19 U2OS 96 5658 Prometaphase +0.05902606321117974 1.422533214320052e-07 BR00118040 DHH final orf E08 U2OS 96 4716 Prometaphase +0.05355549572681902 1.4948294746575674e-07 BR00118039 KCNK1 final orf C22 U2OS 96 5688 Prometaphase +0.06804518362044172 1.8544745530398675e-07 BR00118040 OPRM1 final orf A08 U2OS 96 3480 Prometaphase +0.05869071500022985 2.3361372753734942e-07 BR00118040 MMP2 final orf F06 U2OS 96 4614 Prometaphase +0.047938502703561536 2.501774870998212e-07 BR00118040 ADORA2A final orf O23 U2OS 96 6888 Prometaphase +0.08465115114801905 2.930345973058484e-07 BR00118040 HSD11B1 final orf C02 U2OS 96 2190 Prometaphase +0.06394103541865079 3.5376929033864016e-07 BR00118039 KRAS final orf D17 U2OS 96 3786 Prometaphase +0.0510173742423124 3.9322804349338926e-07 BR00118039 PLD1 final orf L05 U2OS 96 5910 Prometaphase +0.05583361355975628 4.369351779823394e-07 BR00118040 F10 final orf I04 U2OS 96 4896 Prometaphase +0.04821912465984005 5.61803678878178e-07 BR00118039 KCNJ1 final orf E22 U2OS 96 6468 Prometaphase +0.05371069016172121 5.62763931356017e-07 BR00118040 FPR1 final orf L04 U2OS 96 5220 Prometaphase +0.05375096674400619 6.441213611889655e-07 BR00118040 AKR1C1 final orf I01 U2OS 96 5172 Prometaphase +0.05213424568263278 6.801000856008692e-07 BR00118039 HCK final orf O01 U2OS 96 5454 Prometaphase 0.19652471855115028 2.1170381749796076e-69 BR00118039 LYN final orf M05 U2OS 96 4086 SmallIrregular 0.16873783818844862 3.0849619882015106e-51 BR00118039 LYN final orf C20 U2OS 96 4080 SmallIrregular 0.20657487531262048 1.785070174532028e-45 BR00118040 LYN final orf M05 U2OS 96 2412 SmallIrregular @@ -1799,1803 +17909,93 @@ comparison_metric_value p_value Metadata_Plate treatment Metadata_model_type tre 0.2009766504681759 5.961586219305216e-35 BR00118039 DYRK1B final orf M12 U2OS 96 1950 SmallIrregular 0.10910262872360638 1.7947460475716835e-32 BR00118040 PTGIS final orf F16 U2OS 96 6180 SmallIrregular 0.13934674608045103 2.789557646088558e-32 BR00118039 KRAS final orf F08 U2OS 96 3762 SmallIrregular -0.12274598468055706 2.7355391456191807e-09 BR00116992 polydatin shuffled compound K08 A549 24 1346 ADCCM -0.1128311609249133 4.912343340903369e-09 BR00116991 BQ-788 shuffled compound E08 A549 24 1546 ADCCM -0.09828035009836196 6.39948728804533e-08 BR00116993 LY2109761 shuffled compound M02 A549 24 1777 ADCCM -0.14182151045409438 3.7549014619118183e-07 BR00116991 NSC-663284 shuffled compound G06 A549 24 765 ADCCM -0.14423016857492169 1.4885803791486167e-06 BR00116991 NVP-HSP990 shuffled compound E23 A549 24 668 ADCCM -0.1104014598540146 3.0923797385215015e-06 BR00116991 quinine shuffled compound A05 A549 24 1096 ADCCM -0.18449197860962566 5.600150827403536e-06 BR00116991 LDN-212854 shuffled compound K01 A549 24 374 ADCCM -0.10227065898245874 7.85819403626765e-06 BR00116993 polydatin shuffled compound K08 A549 24 1177 ADCCM -0.13101838215240277 1.544651806509452e-05 BR00116994 ganetespib shuffled compound I17 A549 24 679 ADCCM -0.11565750994774437 3.1359532868720295e-05 BR00116994 fludarabine-phosphate shuffled compound N12 A549 24 816 ADCCM -0.22349520960737762 2.0325024264301544e-34 BR00116991 BQ-788 shuffled compound E08 A549 24 1546 Anaphase -0.3873626373626374 9.63773632124003e-25 BR00116994 romidepsin shuffled compound N19 A549 24 364 Anaphase -0.3154375860773757 5.951572555650058e-22 BR00116992 CYT-997 shuffled compound C09 A549 24 489 Anaphase -0.33171912832929784 1.624348786233374e-20 BR00116992 TG-101348 shuffled compound M20 A549 24 413 Anaphase -0.26161337412762214 1.7180987761144053e-19 BR00116994 danusertib shuffled compound E05 A549 24 633 Anaphase -0.31676661778546256 2.168580307115256e-19 BR00116994 KG-5 shuffled compound C13 A549 24 427 Anaphase -0.2855233252436535 9.05644867802445e-19 BR00116993 CYT-997 shuffled compound C09 A549 24 509 Anaphase -0.3248272954743255 1.55561483658918e-18 BR00116994 TG-101348 shuffled compound M20 A549 24 384 Anaphase -0.29708632815518976 2.5815171897473905e-18 BR00116993 CYT-997 shuffled compound E06 A549 24 456 Anaphase -0.2165266452516267 4.666138472021486e-18 BR00116992 azeliragon shuffled compound C08 A549 24 855 Anaphase -0.4433021890216929 1.866147442431475e-137 BR00116991 BQ-788 shuffled compound E08 A549 24 1546 Apoptosis -0.38777372262773724 7.108730986315749e-74 BR00116991 quinine shuffled compound A05 A549 24 1096 Apoptosis -0.41193905355057553 1.6443668738261223e-56 BR00116991 fludarabine-phosphate shuffled compound N12 A549 24 735 Apoptosis -0.3770015341099765 2.9984950758528493e-52 BR00116994 fludarabine-phosphate shuffled compound N12 A549 24 816 Apoptosis -0.38690032696843 3.2373556956542444e-47 BR00116992 fludarabine-phosphate shuffled compound N12 A549 24 697 Apoptosis -0.3654130146082337 3.099255701283309e-45 BR00116993 fludarabine-phosphate shuffled compound N12 A549 24 753 Apoptosis -0.3472658522396742 2.2863725844317662e-41 BR00116991 NSC-663284 shuffled compound G06 A549 24 765 Apoptosis -0.2505098730465939 1.6610945521739603e-37 BR00116992 polydatin shuffled compound K08 A549 24 1346 Apoptosis -0.3435249379455388 2.8816329239641206e-37 BR00116993 KU-60019 shuffled compound I07 A549 24 702 Apoptosis -0.2648647714274119 3.9904832142580605e-36 BR00116991 AC-710 shuffled compound I03 A549 24 1154 Apoptosis -0.3683052512558157 6.57815797232687e-45 BR00116991 fludarabine-phosphate shuffled compound N12 A549 24 735 Binuclear -0.34993887530562345 7.938553391557986e-45 BR00116994 fludarabine-phosphate shuffled compound N12 A549 24 816 Binuclear -0.32298850574712645 1.5817374938353897e-36 BR00116994 geldanamycin shuffled compound L01 A549 24 780 Binuclear -0.3357996987006465 3.884766946827221e-36 BR00116994 ganetespib shuffled compound M10 A549 24 712 Binuclear -0.32966340519249676 3.3502805850327427e-34 BR00116992 fludarabine-phosphate shuffled compound N12 A549 24 697 Binuclear -0.32755204940342864 3.0086784011338456e-32 BR00116991 NVP-HSP990 shuffled compound E23 A549 24 668 Binuclear -0.32498772704958273 3.6844511301606007e-32 BR00116994 ganetespib shuffled compound I17 A549 24 679 Binuclear -0.30852589641434264 3.687469957974876e-32 BR00116993 fludarabine-phosphate shuffled compound N12 A549 24 753 Binuclear -0.3063766141452435 4.492281175567239e-31 BR00116991 geldanamycin shuffled compound L01 A549 24 736 Binuclear -0.360989469394346 3.602080427583935e-30 BR00116994 NVP-HSP990 shuffled compound E23 A549 24 511 Binuclear -0.33579984140895625 6.9960659802094595e-25 BR00116992 CYT-997 shuffled compound C09 A549 24 489 Elongated -0.30456852791878175 1.3509677671711495e-24 BR00116992 BI-2536 shuffled compound I14 A549 24 591 Elongated -0.27624739002087983 3.976563829315148e-22 BR00116994 BI-2536 shuffled compound I14 A549 24 645 Elongated -0.31095639885282017 1.6431858994164623e-21 BR00116992 briciclib shuffled compound H01 A549 24 490 Elongated -0.2867251029675784 8.289047250821142e-21 BR00116991 BI-2536 shuffled compound I14 A549 24 557 Elongated -0.2772290587219344 4.894559681618674e-20 BR00116994 BI-2536 shuffled compound E21 A549 24 576 Elongated -0.2838827838827839 8.794005396264558e-20 BR00116994 briciclib shuffled compound H01 A549 24 546 Elongated -0.31934731934731936 9.701357404347512e-20 BR00116992 colchicine shuffled compound K17 A549 24 429 Elongated -0.27051483301483303 1.2424337438542477e-19 BR00116991 BI-2536 shuffled compound E21 A549 24 594 Elongated -0.3084533531304133 1.6129989028754712e-19 BR00116992 CYT-997 shuffled compound E06 A549 24 450 Elongated -0.3308216803420779 2.5793725182289945e-25 BR00116993 CYT-997 shuffled compound C09 A549 24 509 Grape -0.3279829723300363 6.406442462676164e-24 BR00116992 CYT-997 shuffled compound C09 A549 24 489 Grape -0.34045328077904013 7.868639627860014e-24 BR00116993 CYT-997 shuffled compound E06 A549 24 456 Grape -0.3348379114080673 7.352793475626357e-23 BR00116992 CYT-997 shuffled compound E06 A549 24 450 Grape -0.3206146132949824 8.205291828384056e-21 BR00116991 colchicine shuffled compound K17 A549 24 447 Grape -0.31715818265024853 9.095736331273251e-20 BR00116991 KG-5 shuffled compound C13 A549 24 433 Grape -0.21947996332367384 6.634742121083279e-19 BR00116993 BAX-channel-blocker shuffled compound I19 A549 24 871 Grape -0.28726883582233126 1.1318431869365141e-18 BR00116991 briciclib shuffled compound H01 A549 24 498 Grape -0.28213973980630946 1.254701208360046e-17 BR00116992 briciclib shuffled compound H01 A549 24 490 Grape -0.16714082503556188 1.4743385583196718e-17 BR00116994 RKI-1447 shuffled compound J04 A549 24 1406 Grape -0.28604413014916147 5.424775014131085e-17 BR00116993 CYT-997 shuffled compound E06 A549 24 456 Hole -0.26251309854663085 1.0276940782869743e-14 BR00116993 briciclib shuffled compound H01 A549 24 467 Hole -0.1325724397341206 4.567731232267985e-14 BR00116993 LY2109761 shuffled compound M02 A549 24 1777 Hole -0.22515067126646993 2.3955297855951463e-11 BR00116992 briciclib shuffled compound H01 A549 24 490 Hole -0.22272322824231056 2.4748014836491573e-11 BR00116991 briciclib shuffled compound H01 A549 24 498 Hole -0.1301564722617354 8.53161790546576e-11 BR00116994 RKI-1447 shuffled compound J04 A549 24 1406 Hole -0.20512820512820512 1.8261827274383994e-10 BR00116994 briciclib shuffled compound H01 A549 24 546 Hole -0.18487886382623225 7.324354926957327e-10 BR00116993 BI-2536 shuffled compound I14 A549 24 630 Hole -0.17713778289773682 2.745947691134789e-09 BR00116994 BI-2536 shuffled compound I14 A549 24 645 Hole -0.2115881284335398 7.646304586037615e-09 BR00116994 KG-5 shuffled compound C13 A549 24 427 Hole -0.43613789073911774 2.540589581950665e-42 BR00116992 CYT-997 shuffled compound C09 A549 24 489 Interphase -0.43080029368575623 1.8313374936390743e-38 BR00116993 CYT-997 shuffled compound E06 A549 24 456 Interphase -0.3985327735982377 2.8941126212575185e-35 BR00116992 briciclib shuffled compound H01 A549 24 490 Interphase -0.4100601230425056 3.3518528448715455e-34 BR00116991 colchicine shuffled compound K17 A549 24 447 Interphase -0.3797026079587041 3.725325040293366e-33 BR00116993 CYT-997 shuffled compound C09 A549 24 509 Interphase -0.39522490374683067 1.1859282424739607e-32 BR00116991 ixabepilone shuffled compound J21 A549 24 463 Interphase -0.4050297463841381 1.645529615446697e-32 BR00116991 KG-5 shuffled compound C13 A549 24 433 Interphase -0.3927443702053947 1.3707383465675496e-31 BR00116992 CYT-997 shuffled compound E06 A549 24 450 Interphase -0.3622155671665038 1.4556045415504841e-31 BR00116992 ixabepilone shuffled compound J21 A549 24 531 Interphase -0.35714285714285715 2.5522101775249583e-31 BR00116994 briciclib shuffled compound H01 A549 24 546 Interphase -0.2230665222307443 1.840991566173777e-31 BR00116994 polydatin shuffled compound K08 A549 24 1421 Large -0.22427881474723363 3.890501190839234e-30 BR00116992 polydatin shuffled compound K08 A549 24 1346 Large -0.2796812749003984 2.3215215424050955e-26 BR00116993 fludarabine-phosphate shuffled compound N12 A549 24 753 Large -0.211021001599238 1.8943784912699948e-23 BR00116993 polydatin shuffled compound K08 A549 24 1177 Large -0.16339709125937124 9.27259991239231e-22 BR00116992 LY2109761 shuffled compound M02 A549 24 1822 Large -0.25652375391573523 1.1538004813232576e-21 BR00116991 fludarabine-phosphate shuffled compound N12 A549 24 735 Large -0.20290527473420125 6.0700260363529736e-21 BR00116991 polydatin shuffled compound K08 A549 24 1132 Large -0.2327532479984659 5.696470847895081e-20 BR00116994 fludarabine-phosphate shuffled compound N12 A549 24 816 Large -0.1426392385623179 3.1117577012082996e-16 BR00116993 LY2109761 shuffled compound M02 A549 24 1777 Large -0.21607365313401253 4.383405304936308e-16 BR00116992 KU-60019 shuffled compound I07 A549 24 765 Large -0.2697510756605098 1.6069861867987295e-43 BR00116992 polydatin shuffled compound K08 A549 24 1346 Metaphase -0.2495710411247025 2.0861285282055412e-39 BR00116994 polydatin shuffled compound K08 A549 24 1421 Metaphase -0.27713990245975134 7.134508477790633e-39 BR00116991 polydatin shuffled compound K08 A549 24 1132 Metaphase -0.31365366659484306 7.579858038697082e-39 BR00116992 AMG900 shuffled compound N09 A549 24 882 Metaphase -0.2663037027071941 2.933576900896999e-37 BR00116993 polydatin shuffled compound K08 A549 24 1177 Metaphase -0.3205069347334723 9.742480929095072e-35 BR00116991 AMG900 shuffled compound N09 A549 24 753 Metaphase -0.3165284650330164 1.0168429947019364e-34 BR00116993 AMG900 shuffled compound N09 A549 24 770 Metaphase -0.309184190086257 2.615274781406483e-34 BR00116994 AMG900 shuffled compound N09 A549 24 798 Metaphase -0.30200830823402736 2.195594313261318e-30 BR00116994 PF-431396 shuffled compound L20 A549 24 744 Metaphase -0.31219701944512995 2.4959645143698195e-30 BR00116993 GSK1070916 shuffled compound C04 A549 24 694 Metaphase -0.3315018315018315 5.864706006378684e-27 BR00116994 briciclib shuffled compound H01 A549 24 546 MetaphaseAlignment -0.314774414106428 2.9602307972277406e-23 BR00116992 epothilone-b shuffled compound F07 A549 24 517 MetaphaseAlignment -0.34260981855588873 1.055590951499841e-22 BR00116994 KG-5 shuffled compound C13 A549 24 427 MetaphaseAlignment -0.32944006492000927 2.590410017619411e-22 BR00116993 CYT-997 shuffled compound E06 A549 24 456 MetaphaseAlignment -0.3173198113601269 3.1252056964200484e-22 BR00116992 CYT-997 shuffled compound C09 A549 24 489 MetaphaseAlignment -0.31100581686505646 3.239376394575738e-22 BR00116993 CYT-997 shuffled compound C09 A549 24 509 MetaphaseAlignment -0.2917797502632767 4.10619650268576e-22 BR00116994 epothilone-b shuffled compound F07 A549 24 575 MetaphaseAlignment -0.3473987053464397 2.06016520100774e-21 BR00116994 CYT-997 shuffled compound C09 A549 24 388 MetaphaseAlignment -0.305712639854608 4.8875600507202645e-21 BR00116991 epothilone-b shuffled compound F07 A549 24 494 MetaphaseAlignment -0.3186134781187945 1.2993709614943977e-20 BR00116994 CYT-997 shuffled compound E06 A549 24 447 MetaphaseAlignment -0.3306399482870071 3.3966651288187203e-43 BR00116992 AMG900 shuffled compound N09 A549 24 882 OutOfFocus -0.33245912596853205 2.1751979712797444e-37 BR00116991 AMG900 shuffled compound N09 A549 24 753 OutOfFocus -0.31782041105838243 5.324315259679161e-35 BR00116993 AMG900 shuffled compound N09 A549 24 770 OutOfFocus -0.23982745143196268 1.881490805790883e-34 BR00116992 polydatin shuffled compound K08 A549 24 1346 OutOfFocus -0.25946659043405723 4.413301625570488e-34 BR00116991 polydatin shuffled compound K08 A549 24 1132 OutOfFocus -0.3337039091546745 4.817449858359706e-33 BR00116993 PF-431396 shuffled compound L20 A549 24 659 OutOfFocus -0.30289179661827087 6.50834207562228e-33 BR00116994 AMG900 shuffled compound N09 A549 24 798 OutOfFocus -0.24994514534505197 8.175552928030885e-33 BR00116993 polydatin shuffled compound K08 A549 24 1177 OutOfFocus -0.2937249666221629 6.895811941406956e-29 BR00116992 PF-431396 shuffled compound L20 A549 24 749 OutOfFocus -0.21247054614174224 1.434777862338991e-28 BR00116994 polydatin shuffled compound K08 A549 24 1421 OutOfFocus -0.17089452603471295 5.763670321748995e-10 BR00116992 PF-431396 shuffled compound L20 A549 24 749 Polylobed -0.16005291005291006 7.238664863688971e-09 BR00116994 azeliragon shuffled compound C08 A549 24 756 Polylobed -0.11234808313744743 4.077367436281514e-08 BR00116991 RKI-1447 shuffled compound J04 A549 24 1394 Polylobed -0.12819022431472843 9.078751338527792e-08 BR00116992 motesanib shuffled compound K24 A549 24 1015 Polylobed -0.1884902233557462 1.5718087333474093e-07 BR00116993 CYT-997 shuffled compound E06 A549 24 456 Polylobed -0.1350876317234458 2.0134627239449756e-07 BR00116993 BAX-channel-blocker shuffled compound I19 A549 24 871 Polylobed -0.14042002951454818 2.9505854826604884e-07 BR00116991 NNC-55-0396 shuffled compound A16 A549 24 791 Polylobed -0.16014060373657735 3.2388098345686917e-07 BR00116992 danusertib shuffled compound N18 A549 24 603 Polylobed -0.10241820768136557 7.709087036601777e-07 BR00116994 RKI-1447 shuffled compound J04 A549 24 1406 Polylobed -0.1365016543116807 1.2153528164967956e-06 BR00116993 danusertib shuffled compound N18 A549 24 758 Polylobed -0.31848544824794206 1.1389014957446176e-23 BR00116992 epothilone-b shuffled compound F07 A549 24 517 Prometaphase -0.23425524055776156 1.0751474257279841e-21 BR00116992 AMG900 shuffled compound N09 A549 24 882 Prometaphase -0.3154944126209034 7.247462701092876e-21 BR00116991 ixabepilone shuffled compound J21 A549 24 463 Prometaphase -0.3047430894177018 7.479825296881381e-21 BR00116991 epothilone-b shuffled compound F07 A549 24 494 Prometaphase -0.28682936153944183 1.0357648149918344e-19 BR00116992 ixabepilone shuffled compound J21 A549 24 531 Prometaphase -0.27430720625846244 1.4024224130500024e-19 BR00116994 epothilone-b shuffled compound F07 A549 24 575 Prometaphase -0.23715117455124315 4.738343587044711e-19 BR00116991 AMG900 shuffled compound N09 A549 24 753 Prometaphase -0.2656514382402707 9.646662935579058e-19 BR00116992 BI-2536 shuffled compound I14 A549 24 591 Prometaphase -0.22770854363009155 1.0510552263683456e-18 BR00116994 AMG900 shuffled compound N09 A549 24 798 Prometaphase -0.18874991017674092 3.640670050608248e-18 BR00116991 polydatin shuffled compound K08 A549 24 1132 Prometaphase -0.36763179746970936 1.227867582614855e-93 BR00116991 BQ-788 shuffled compound E08 A549 24 1546 SmallIrregular -0.3938584779706275 3.0528186293221013e-52 BR00116992 PF-431396 shuffled compound L20 A549 24 749 SmallIrregular -0.3757008581680047 8.401816160816504e-51 BR00116994 AMG900 shuffled compound N09 A549 24 798 SmallIrregular -0.38716770701471037 4.315832117365894e-50 BR00116994 PF-431396 shuffled compound L20 A549 24 744 SmallIrregular -0.4170369163630619 5.446103361125271e-50 BR00116994 danusertib shuffled compound N18 A549 24 636 SmallIrregular -0.3790559615841271 1.0504190384697476e-48 BR00116991 AMG900 shuffled compound N09 A549 24 753 SmallIrregular -0.3440889176183294 8.525484270426801e-47 BR00116992 AMG900 shuffled compound N09 A549 24 882 SmallIrregular -0.36617176920607 8.727114871536086e-46 BR00116993 danusertib shuffled compound N18 A549 24 758 SmallIrregular -0.29927007299270075 1.0727323877035516e-43 BR00116991 quinine shuffled compound A05 A549 24 1096 SmallIrregular -0.3650137741046832 2.172296277439532e-43 BR00116991 PF-431396 shuffled compound L20 A549 24 726 SmallIrregular -0.40484118852459017 1.0586866412792302e-09 BR00117019 romidepsin shuffled compound N19 A549 48 122 ADCCM -0.11988427460671448 2.5416317494277827e-09 BR00117017 FK-866 shuffled compound D08 A549 48 1410 ADCCM -0.1985704079889422 2.7176309578804667e-09 BR00117017 fludarabine-phosphate shuffled compound N12 A549 48 507 ADCCM -0.259927797833935 1.242732692491028e-08 BR00117017 AR-12 shuffled compound C10 A549 48 277 ADCCM -0.07680583496599871 8.028962004788784e-08 BR00117015 LY2109761 shuffled compound M02 A549 48 2866 ADCCM -0.3226617975248529 9.351537250340555e-08 BR00117016 romidepsin shuffled compound N19 A549 48 159 ADCCM -0.361503674392312 1.8888723493699612e-07 BR00117008 AR-12 shuffled compound C10 A549 48 116 ADCCM -0.07833011958728314 2.4424975654552553e-07 BR00117055 formononetin shuffled compound K02 A549 48 2585 ADCCM -0.1013964872565096 3.351514774706543e-07 BR00117017 fludarabine shuffled compound B06 A549 48 1509 ADCCM -0.20969981945519117 1.1857160463737996e-06 BR00117019 AR-12 shuffled compound C10 A549 48 318 ADCCM -0.22075291956952744 4.274113601415747e-32 BR00117017 ingenol-mebutate shuffled compound M11 A549 48 1477 Anaphase -0.7094494047619048 1.3412950220861612e-31 BR00117050 romidepsin shuffled compound N19 A549 48 126 Anaphase -0.16595073312973818 3.9380665919337496e-30 BR00117015 RKI-1447 shuffled compound J04 A549 48 2466 Anaphase -0.22916464097606928 2.1462900803475643e-29 BR00117015 ingenol-mebutate shuffled compound M11 A549 48 1259 Anaphase -0.25488069414316705 1.0314642261437775e-26 BR00117054 ingenol-mebutate shuffled compound M11 A549 48 922 Anaphase -0.592290525461554 4.3095132709499137e-26 BR00117016 romidepsin shuffled compound N19 A549 48 159 Anaphase -0.20814232349404949 2.41471914717834e-25 BR00117015 NNC-55-0396 shuffled compound A16 A549 48 1307 Anaphase -0.6389025590551181 7.56465608373016e-25 BR00117053 romidepsin shuffled compound N19 A549 48 127 Anaphase -0.20746297739672642 1.1653289056092784e-24 BR00117016 ingenol-mebutate shuffled compound M11 A549 48 1280 Anaphase -0.624138779527559 4.0487547811916075e-24 BR00117015 romidepsin shuffled compound N19 A549 48 127 Anaphase -0.30107125440236265 7.707706600571655e-61 BR00117017 fludarabine shuffled compound B06 A549 48 1509 Apoptosis -0.27298137694043967 1.2913460759079542e-57 BR00117017 JTE-607 shuffled compound C14 A549 48 1739 Apoptosis -0.2771553743567581 3.0416451714719744e-55 BR00117015 fludarabine shuffled compound B06 A549 48 1615 Apoptosis -0.3484698914116486 5.877813255742276e-55 BR00117055 fludarabine shuffled compound B06 A549 48 1013 Apoptosis -0.483638509683331 3.526799364498119e-54 BR00117017 fludarabine-phosphate shuffled compound N12 A549 48 507 Apoptosis -0.28026285087517605 1.6575042290483447e-53 BR00117016 fludarabine shuffled compound B06 A549 48 1533 Apoptosis -0.6247067188055457 1.792000957485411e-53 BR00117051 fludarabine-phosphate shuffled compound N12 A549 48 290 Apoptosis -0.49500805152979066 1.593744075299869e-51 BR00117015 fludarabine-phosphate shuffled compound N12 A549 48 459 Apoptosis -0.26407704695684214 3.076125489344568e-49 BR00117019 fludarabine shuffled compound B06 A549 48 1588 Apoptosis -0.2983830119109241 1.2898674821009595e-47 BR00117055 JTE-607 shuffled compound C14 A549 48 1202 Apoptosis -0.5257873549609282 1.0845752984827347e-52 BR00117019 fludarabine-phosphate shuffled compound N12 A549 48 412 Binuclear -0.27093888273018635 1.0087661741851583e-51 BR00117019 fludarabine shuffled compound B06 A549 48 1588 Binuclear -0.6041118615949758 7.647337565433841e-50 BR00117051 fludarabine-phosphate shuffled compound N12 A549 48 290 Binuclear -0.6321078431372549 1.945344643840995e-48 BR00117052 fludarabine-phosphate shuffled compound N12 A549 48 255 Binuclear -0.6060657261130354 3.068355337514279e-46 BR00117053 fludarabine-phosphate shuffled compound N12 A549 48 267 Binuclear -0.46032963910201763 1.4589629120179304e-44 BR00117015 fludarabine-phosphate shuffled compound N12 A549 48 459 Binuclear -0.4384172762428365 2.337905616248886e-44 BR00117017 fludarabine-phosphate shuffled compound N12 A549 48 507 Binuclear -0.2485438972572222 2.575272584058205e-44 BR00117015 fludarabine shuffled compound B06 A549 48 1615 Binuclear -0.24796014886131124 3.824580832794876e-41 BR00117017 fludarabine shuffled compound B06 A549 48 1509 Binuclear -0.54242245601306 7.683301430317363e-41 BR00117050 fludarabine-phosphate shuffled compound N12 A549 48 296 Binuclear -0.2701291763791764 5.104658553276538e-23 BR00117015 PF-431396 shuffled compound L20 A549 48 702 Elongated -0.2493285308780383 4.0099126272017232e-22 BR00117019 AMG900 shuffled compound N09 A549 48 795 Elongated -0.2756950952827241 4.2285647478902275e-20 BR00117015 aminopurvalanol-a shuffled compound K03 A549 48 582 Elongated -0.24319314944314943 9.969867229690238e-19 BR00117015 AMG900 shuffled compound N09 A549 48 702 Elongated -0.2540294951667141 5.601084681107536e-18 BR00117019 aminopurvalanol-a shuffled compound K03 A549 48 618 Elongated -0.2891505204475459 3.4047277712343406e-17 BR00117053 AMG900 shuffled compound N09 A549 48 452 Elongated -0.21976592977893367 1.1206564607897339e-16 BR00117017 AMG900 shuffled compound N09 A549 48 769 Elongated -0.24809013434136515 1.4473562154218613e-16 BR00117055 AMG900 shuffled compound N09 A549 48 593 Elongated -0.31932773109243695 1.7151265160682596e-16 BR00117051 PF-431396 shuffled compound L20 A549 48 357 Elongated -0.34407309994558316 3.221118399071588e-16 BR00117050 fludarabine-phosphate shuffled compound N12 A549 48 296 Elongated -0.2832464759297446 6.678912538343714e-45 BR00117015 ingenol-mebutate shuffled compound M11 A549 48 1259 Grape -0.24965815710170325 6.136190318821195e-41 BR00117017 ingenol-mebutate shuffled compound M11 A549 48 1477 Grape -0.2667119300467654 1.1933350252652506e-40 BR00117016 ingenol-mebutate shuffled compound M11 A549 48 1280 Grape -0.24391717062880816 3.640314374355162e-37 BR00117019 NNC-55-0396 shuffled compound A16 A549 48 1407 Grape -0.3012878337843685 9.470780441402483e-37 BR00117055 ingenol-mebutate shuffled compound M11 A549 48 906 Grape -0.17558402411454407 3.872935452400234e-36 BR00117019 RKI-1447 shuffled compound J04 A549 48 2654 Grape -0.2416119817893075 5.0463277312328545e-34 BR00117015 NNC-55-0396 shuffled compound A16 A549 48 1307 Grape -0.20935672514619882 3.299634673031646e-33 BR00117019 AC-710 shuffled compound I03 A549 48 1710 Grape -0.23536303005153927 8.036939436655026e-32 BR00117016 NNC-55-0396 shuffled compound A16 A549 48 1290 Grape -0.24901891252955083 3.525738232542078e-31 BR00117019 ingenol-mebutate shuffled compound M11 A549 48 1128 Grape -0.14853801169590644 7.239953866412222e-17 BR00117019 AC-710 shuffled compound I03 A549 48 1710 Hole -0.10741640204960438 1.4027578396070028e-12 BR00117015 ibudilast shuffled compound G24 A549 48 2413 Hole -0.10662848934603421 1.6033292041042811e-12 BR00117015 ANR-94 shuffled compound D24 A549 48 2439 Hole -0.1214210998898444 3.0266096939887965e-12 BR00117016 AC-710 shuffled compound I03 A549 48 1829 Hole -0.0998492840994725 6.202632402073241e-12 BR00117019 RKI-1447 shuffled compound J04 A549 48 2654 Hole -0.0898975727545863 1.5991575823117369e-10 BR00117015 LY2109761 shuffled compound M02 A549 48 2866 Hole -0.17496635262449528 2.3902866575793184e-10 BR00117052 NNC-55-0396 shuffled compound A16 A549 48 743 Hole -0.08530872110915745 1.735088201962197e-09 BR00117015 nilvadipine shuffled compound I01 A549 48 2856 Hole -0.18011934828901105 1.7961323037914047e-09 BR00117050 NNC-55-0396 shuffled compound A16 A549 48 635 Hole -0.09544095665171898 2.7065261848748443e-09 BR00117015 PF-05190457 shuffled compound J24 A549 48 2230 Hole -0.39488636363636365 6.886063862801505e-25 BR00117015 azeliragon shuffled compound C08 A549 48 352 Interphase -0.3333333333333333 1.1044590221804345e-22 BR00117015 CYT-997 shuffled compound E06 A549 48 453 Interphase -0.22656163331261134 1.9326767856248286e-22 BR00117015 BAN-ORL-24 shuffled compound A15 A549 48 978 Interphase -0.4462809917355372 4.5704944456396155e-22 BR00117008 briciclib shuffled compound H01 A549 48 242 Interphase -0.33011306066351664 5.748209161975527e-22 BR00117017 colchicine shuffled compound K17 A549 48 446 Interphase -0.31313131313131315 7.692304958958806e-22 BR00117017 CYT-997 shuffled compound C09 A549 48 495 Interphase -0.3102962745673218 2.4939325079300935e-21 BR00117017 oxibendazole shuffled compound M19 A549 48 490 Interphase -0.284185956039681 2.6932302391393234e-21 BR00117015 aminopurvalanol-a shuffled compound K03 A549 48 582 Interphase -0.13376036171816127 4.1741449743717385e-21 BR00117019 RKI-1447 shuffled compound J04 A549 48 2654 Interphase -0.3131991051454139 9.042960726396591e-20 BR00117019 briciclib shuffled compound H01 A549 48 447 Interphase -0.18546643959760534 5.5751150999929487e-33 BR00117053 LY2109761 shuffled compound M02 A549 48 2161 Large -0.14841704344915577 1.8314420954401389e-28 BR00117019 LY2109761 shuffled compound M02 A549 48 2916 Large -0.1485822819552275 4.587583515803788e-28 BR00117015 LY2109761 shuffled compound M02 A549 48 2866 Large -0.17583582871599865 5.750666301013147e-27 BR00117019 PP-2 shuffled compound J10 A549 48 1961 Large -0.14542190348981748 6.983565767959362e-27 BR00117017 LY2109761 shuffled compound M02 A549 48 2862 Large -0.14936487078405605 1.2671636110497073e-22 BR00117055 LY2109761 shuffled compound M02 A549 48 2283 Large -0.15203824573457003 5.893845582143075e-22 BR00117017 PP-2 shuffled compound J10 A549 48 2132 Large -0.15612791796035005 2.6876062847011364e-21 BR00117015 PP-2 shuffled compound J10 A549 48 1962 Large -0.16393704420036553 6.029199736967346e-21 BR00117051 LY2109761 shuffled compound M02 A549 48 1746 Large -0.11453073516185705 2.161276603714883e-20 BR00117015 CC-401 shuffled compound M09 A549 48 3491 Large -0.3602080624187256 1.0207795044981619e-44 BR00117017 AMG900 shuffled compound N09 A549 48 769 Metaphase -0.4395755837404204 2.2136934319002782e-37 BR00117052 AMG900 shuffled compound N09 A549 48 424 Metaphase -0.16658181421591164 9.077469838677042e-36 BR00117019 LY2109761 shuffled compound M02 A549 48 2916 Metaphase -0.33584789537311793 2.6859631732099974e-34 BR00117016 AMG900 shuffled compound N09 A549 48 674 Metaphase -0.2981116173301847 1.2259234333588846e-31 BR00117019 AMG900 shuffled compound N09 A549 48 795 Metaphase -0.1790091275261932 9.75312595326027e-31 BR00117053 LY2109761 shuffled compound M02 A549 48 2161 Metaphase -0.3812716853144127 7.968166068787703e-30 BR00117053 AMG900 shuffled compound N09 A549 48 452 Metaphase -0.14796381392386607 8.582567885406672e-28 BR00117017 LY2109761 shuffled compound M02 A549 48 2862 Metaphase -0.284313448840228 2.159274806290053e-27 BR00117017 PF-431396 shuffled compound L20 A549 48 752 Metaphase -0.37833189510523035 1.078011731997063e-26 BR00117053 PF-431396 shuffled compound L20 A549 48 409 Metaphase -0.1607154999364381 2.6470266267604546e-28 BR00117015 RKI-1447 shuffled compound J04 A549 48 2466 MetaphaseAlignment -0.32783505154639175 1.8354910512696018e-23 BR00117052 KU-60019 shuffled compound I07 A549 48 485 MetaphaseAlignment -0.13790504898266767 2.0650600514260173e-22 BR00117019 RKI-1447 shuffled compound J04 A549 48 2654 MetaphaseAlignment -0.22501927883043107 1.324431928034684e-19 BR00117052 cyclosporine shuffled compound M15 A549 48 861 MetaphaseAlignment -0.17167586106186222 1.800654414944038e-19 BR00117017 ingenol-mebutate shuffled compound M11 A549 48 1477 MetaphaseAlignment -0.18433931484502447 1.2931264871651025e-18 BR00117016 cyclosporine shuffled compound M15 A549 48 1226 MetaphaseAlignment -0.3409090909090909 1.5850021842667822e-18 BR00117015 azeliragon shuffled compound C08 A549 48 352 MetaphaseAlignment -0.1531842498729916 1.748928824005888e-17 BR00117054 RKI-1447 shuffled compound J04 A549 48 1665 MetaphaseAlignment -0.35431549234610793 1.8449128425676025e-17 BR00117051 BAX-channel-blocker shuffled compound I19 A549 48 302 MetaphaseAlignment -0.1759408569902426 1.8992084673794388e-17 BR00117015 ingenol-mebutate shuffled compound M11 A549 48 1259 MetaphaseAlignment -0.3732119635890767 4.683021932522889e-48 BR00117017 AMG900 shuffled compound N09 A549 48 769 OutOfFocus -0.41832636802925427 1.84098068196602e-39 BR00117050 AMG900 shuffled compound N09 A549 48 496 OutOfFocus -0.42301469728275704 7.256603872185046e-37 BR00117053 AMG900 shuffled compound N09 A549 48 452 OutOfFocus -0.42990633263120154 1.0441750211064824e-35 BR00117052 AMG900 shuffled compound N09 A549 48 424 OutOfFocus -0.31885617134149785 1.8498754112865028e-34 BR00117017 PF-431396 shuffled compound L20 A549 48 752 OutOfFocus -0.3111800205137991 2.16520332765786e-34 BR00117019 AMG900 shuffled compound N09 A549 48 795 OutOfFocus -0.22229624395164552 7.396705426308395e-33 BR00117017 NNC-55-0396 shuffled compound A16 A549 48 1491 OutOfFocus -0.23759479435413547 2.342344331562763e-32 BR00117016 NNC-55-0396 shuffled compound A16 A549 48 1290 OutOfFocus -0.22354216572316837 5.418920200645906e-28 BR00117015 ingenol-mebutate shuffled compound M11 A549 48 1259 OutOfFocus -0.21809694873289096 8.566585677810771e-28 BR00117015 NNC-55-0396 shuffled compound A16 A549 48 1307 OutOfFocus -0.19237118347536541 1.2242248514741897e-12 BR00117017 PF-431396 shuffled compound L20 A549 48 752 Polylobed -0.1846553966189857 7.16607163365212e-12 BR00117017 AMG900 shuffled compound N09 A549 48 769 Polylobed -0.24636847403998274 1.7836647285190485e-11 BR00117053 PF-431396 shuffled compound L20 A549 48 409 Polylobed -0.2311800709523995 4.406698565568342e-11 BR00117053 AMG900 shuffled compound N09 A549 48 452 Polylobed -0.11436475092261665 6.56490983518184e-11 BR00117016 AC-710 shuffled compound I03 A549 48 1829 Polylobed -0.09802106690306096 1.4470136671943158e-10 BR00117015 ibudilast shuffled compound G24 A549 48 2413 Polylobed -0.22791646125577017 4.223786955755899e-10 BR00117052 AMG900 shuffled compound N09 A549 48 424 Polylobed -0.11929550378739501 1.1972963789212601e-09 BR00117017 ingenol-mebutate shuffled compound M11 A549 48 1477 Polylobed -0.09064129166409399 1.5891096360400579e-09 BR00117017 RGFP966 shuffled compound H03 A549 48 2532 Polylobed -0.11705352759991584 2.137670049899718e-09 BR00117017 NNC-55-0396 shuffled compound A16 A549 48 1491 Polylobed -0.2856934731934732 1.0055322789946298e-25 BR00117015 AMG900 shuffled compound N09 A549 48 702 Prometaphase -0.2591815153177651 6.4337939322478444e-24 BR00117019 AMG900 shuffled compound N09 A549 48 795 Prometaphase -0.2626788036410923 9.995216296897838e-24 BR00117017 AMG900 shuffled compound N09 A549 48 769 Prometaphase -0.31343283582089554 1.1613819643640647e-23 BR00117017 epothilone-b shuffled compound F07 A549 48 536 Prometaphase -0.2685994560994561 9.345217185456183e-23 BR00117015 PF-431396 shuffled compound L20 A549 48 702 Prometaphase -0.3262153522279833 8.603209374538096e-22 BR00117053 AMG900 shuffled compound N09 A549 48 452 Prometaphase -0.27898468712156366 6.2703514742884035e-21 BR00117055 AMG900 shuffled compound N09 A549 48 593 Prometaphase -0.2908217353484832 8.409730783009433e-21 BR00117015 epothilone-b shuffled compound F07 A549 48 544 Prometaphase -0.2745762711864407 5.61908593830039e-20 BR00117019 epothilone-b shuffled compound F07 A549 48 590 Prometaphase -0.31228431855868777 9.37270917771024e-19 BR00117052 AMG900 shuffled compound N09 A549 48 424 Prometaphase -0.4102966549785718 2.3934859780144244e-60 BR00117019 AMG900 shuffled compound N09 A549 48 795 SmallIrregular -0.41585535465924894 4.639206462270151e-56 BR00117019 PF-431396 shuffled compound L20 A549 48 719 SmallIrregular -0.4194590132090132 7.527239014496287e-56 BR00117015 PF-431396 shuffled compound L20 A549 48 702 SmallIrregular -0.395616993058299 4.793223104974492e-53 BR00117017 PF-431396 shuffled compound L20 A549 48 752 SmallIrregular -0.27065214057513837 3.733097533440155e-48 BR00117017 ingenol-mebutate shuffled compound M11 A549 48 1477 SmallIrregular -0.38669548044548047 2.600345585347852e-47 BR00117015 AMG900 shuffled compound N09 A549 48 702 SmallIrregular -0.408 6.474063718878941e-47 BR00117016 PF-431396 shuffled compound L20 A549 48 625 SmallIrregular -0.3680104031209363 1.050850781149481e-46 BR00117017 AMG900 shuffled compound N09 A549 48 769 SmallIrregular -0.38019342784921417 7.582328421234308e-44 BR00117016 AMG900 shuffled compound N09 A549 48 674 SmallIrregular -0.40088504589336443 3.831028396640996e-43 BR00117055 AMG900 shuffled compound N09 A549 48 593 SmallIrregular -0.15310344827586206 7.878798431029417e-08 BR00116995 RKI-1447 shuffled compound J04 U2OS 24 725 ADCCM -0.14430379746835442 1.3682775705806245e-07 BR00116995 AZ191 shuffled compound I18 U2OS 24 790 ADCCM -0.1289041941004451 5.426774479787479e-06 BR00117026 aripiprazole shuffled compound P24 U2OS 24 758 ADCCM -0.12540725102301456 8.16912586434927e-06 BR00116995 NVS-PAK1-1 shuffled compound N14 U2OS 24 784 ADCCM -0.12795338096269035 9.324034184294725e-06 BR00117024 NVS-PAK1-1 shuffled compound N14 U2OS 24 745 ADCCM -0.13863863863863865 1.834212855240424e-05 BR00117026 AZ191 shuffled compound I18 U2OS 24 592 ADCCM -0.12932054979847613 3.3616494495684896e-05 BR00117024 AZ191 shuffled compound I18 U2OS 24 653 ADCCM -0.10636962447516479 4.2810663671468576e-05 BR00117025 ruxolitinib shuffled compound K04 U2OS 24 941 ADCCM -0.10521172389748079 0.00010279462207864522 BR00117024 ruxolitinib shuffled compound K04 U2OS 24 887 ADCCM -0.11036339165545088 0.00023195026803960427 BR00117024 RKI-1447 shuffled compound J04 U2OS 24 743 ADCCM -0.5173103394540686 1.2162981230545452e-34 BR00117026 SU3327 shuffled compound I20 U2OS 24 278 Anaphase -0.5309748427672956 1.6578751580111762e-34 BR00117024 SU3327 shuffled compound I20 U2OS 24 265 Anaphase -0.5518607257410055 1.895309191854994e-32 BR00117025 SU3327 shuffled compound I20 U2OS 24 226 Anaphase -0.48289425438060424 3.991155229415849e-32 BR00117026 puromycin shuffled compound C22 U2OS 24 299 Anaphase -0.4964349035064223 7.002623362006042e-32 BR00116995 SU3327 shuffled compound I20 U2OS 24 281 Anaphase -0.5277026064663154 7.6136869963815765e-31 BR00117025 AZD7762 shuffled compound I05 U2OS 24 236 Anaphase -0.45956742566912057 8.659123011650792e-29 BR00117025 thiostrepton shuffled compound B02 U2OS 24 297 Anaphase -0.47371728028662335 1.6921205298017332e-28 BR00117025 puromycin shuffled compound C22 U2OS 24 274 Anaphase -0.4729542706466792 6.013252167553103e-27 BR00117026 NSC-632839 shuffled compound M16 U2OS 24 263 Anaphase -0.5346534653465347 8.70568787109489e-27 BR00117026 AZD7762 shuffled compound I05 U2OS 24 202 Anaphase -0.6787021154945683 1.1573138280618078e-58 BR00117024 SU3327 shuffled compound I20 U2OS 24 265 Apoptosis -0.6466768823208581 5.006201288756849e-55 BR00117026 SU3327 shuffled compound I20 U2OS 24 278 Apoptosis -0.6167401860020667 6.483053570882992e-54 BR00117026 puromycin shuffled compound C22 U2OS 24 299 Apoptosis -0.6268147910483677 1.0626819321392754e-50 BR00117025 puromycin shuffled compound C22 U2OS 24 274 Apoptosis -0.5892422097220628 1.3965407891381315e-45 BR00116995 SU3327 shuffled compound I20 U2OS 24 281 Apoptosis -0.5745357783305374 3.00632028838544e-45 BR00117025 delanzomib shuffled compound L11 U2OS 24 295 Apoptosis -0.6166500498504487 6.0529052999011275e-43 BR00117025 AZD7762 shuffled compound I05 U2OS 24 236 Apoptosis -0.5715087504464513 8.578764035372211e-43 BR00117024 delanzomib shuffled compound L11 U2OS 24 282 Apoptosis -0.622599219384009 4.7182670405475416e-42 BR00117025 SU3327 shuffled compound I20 U2OS 24 226 Apoptosis -0.6128494857308416 8.954347010979517e-42 BR00117024 AZD7762 shuffled compound K11 U2OS 24 234 Apoptosis -0.18860759493670887 1.0732677408757964e-12 BR00116995 AZ191 shuffled compound I18 U2OS 24 790 Binuclear -0.19685923392741383 1.6312973473769073e-11 BR00117024 AZ191 shuffled compound I18 U2OS 24 653 Binuclear -0.14994096812278632 1.010744493070026e-08 BR00117025 RKI-1447 shuffled compound J04 U2OS 24 847 Binuclear -0.16137931034482758 1.176819306408669e-08 BR00116995 RKI-1447 shuffled compound J04 U2OS 24 725 Binuclear -0.1727067977067977 3.159672500876679e-08 BR00117026 AZ191 shuffled compound I18 U2OS 24 592 Binuclear -0.1498079509283178 3.429623602133054e-08 BR00117026 RKI-1447 shuffled compound J04 U2OS 24 786 Binuclear -0.15208613728129206 6.507255729992075e-08 BR00117024 RKI-1447 shuffled compound J04 U2OS 24 743 Binuclear -0.1454697986577181 2.590450923259656e-07 BR00117024 NVS-PAK1-1 shuffled compound N14 U2OS 24 745 Binuclear -0.19234107181601215 2.9534308010537275e-07 BR00117025 GSK1070916 shuffled compound C04 U2OS 24 419 Binuclear -0.12856235539627092 3.232298206967044e-07 BR00117025 NVS-PAK1-1 shuffled compound N14 U2OS 24 940 Binuclear -0.3239693313222725 7.055566723758542e-15 BR00117024 ixabepilone shuffled compound J21 U2OS 24 306 Elongated -0.29394700258178 7.914664908252424e-15 BR00117024 epothilone-b shuffled compound F07 U2OS 24 372 Elongated -0.2622907699665232 6.135743148751155e-13 BR00117026 epothilone-b shuffled compound F07 U2OS 24 410 Elongated -0.2147167325428195 1.1590106721807735e-11 BR00117025 PF-431396 shuffled compound L20 U2OS 24 550 Elongated -0.21068997584697055 2.8520581619840937e-11 BR00117026 PF-431396 shuffled compound L20 U2OS 24 556 Elongated -0.22453222453222454 4.903606327563426e-11 BR00117024 danusertib shuffled compound E05 U2OS 24 481 Elongated -0.2127715837621498 5.594258424844651e-11 BR00117025 AMG900 shuffled compound N09 U2OS 24 528 Elongated -0.24463100351425224 8.506722977124214e-11 BR00117025 epothilone-b shuffled compound F07 U2OS 24 390 Elongated -0.3160796211336392 9.082440934936757e-11 BR00117024 oxibendazole shuffled compound M19 U2OS 24 232 Elongated -0.21043056173113978 1.6269776963368406e-10 BR00117024 PF-431396 shuffled compound L20 U2OS 24 519 Elongated -0.5572612921669525 3.387544449201765e-38 BR00117024 SU3327 shuffled compound I20 U2OS 24 265 Grape -0.49640939297695125 7.273706653694804e-32 BR00116995 SU3327 shuffled compound I20 U2OS 24 281 Grape -0.47756019011505596 2.8929606994766754e-29 BR00117026 SU3327 shuffled compound I20 U2OS 24 278 Grape -0.5084824361402017 1.7415733588111516e-27 BR00117025 SU3327 shuffled compound I20 U2OS 24 226 Grape -0.535 1.464559370199308e-26 BR00117024 AZD7762 shuffled compound I05 U2OS 24 200 Grape -0.4500739833664983 4.26617095878665e-26 BR00117024 delanzomib shuffled compound L11 U2OS 24 282 Grape -0.4404486338145806 8.195907226034292e-26 BR00116995 NSC-632839 shuffled compound M16 U2OS 24 289 Grape -0.48518729525708587 8.34380743212834e-26 BR00117025 AZD7762 shuffled compound I05 U2OS 24 236 Grape -0.41304347826086957 5.67960238090992e-25 BR00117026 thiostrepton shuffled compound B02 U2OS 24 322 Grape -0.41818707699427315 1.6399487649846728e-23 BR00117025 delanzomib shuffled compound L11 U2OS 24 295 Grape -0.210806863818912 3.5371031237770213e-10 BR00116995 PF-431396 shuffled compound L20 U2OS 24 498 Hole -0.21544969412989717 1.7947591821395664e-08 BR00117025 epothilone-b shuffled compound F07 U2OS 24 390 Hole -0.15160486212833757 4.078883676737607e-08 BR00117024 baclofen shuffled compound L22 U2OS 24 765 Hole -0.21921462342792164 1.0856482056914365e-07 BR00116995 epothilone-b shuffled compound F07 U2OS 24 341 Hole -0.18449306551889047 1.3841043812802876e-06 BR00117026 epothilone-b shuffled compound F07 U2OS 24 410 Hole -0.13039023246052614 1.9699121247078425e-06 BR00117026 PP-2 shuffled compound J10 U2OS 24 806 Hole -0.18974664510454792 2.11058004729159e-06 BR00117024 epothilone-b shuffled compound F07 U2OS 24 372 Hole -0.17050119420809076 2.3602681714051815e-06 BR00117026 UNC2025 shuffled compound N06 U2OS 24 464 Hole -0.20005706785367802 1.0466274639725947e-05 BR00117025 thiostrepton shuffled compound B02 U2OS 24 297 Hole -0.10949025748086291 1.7987163967074875e-05 BR00117026 VU591 shuffled compound M07 U2OS 24 960 Hole -0.45213379469434833 5.50803212738163e-27 BR00117024 briciclib shuffled compound H01 U2OS 24 289 Interphase -0.40993788819875776 1.3601153070073755e-24 BR00117026 thiostrepton shuffled compound B02 U2OS 24 322 Interphase -0.4479559748427673 2.224792512992446e-24 BR00117024 SU3327 shuffled compound I20 U2OS 24 265 Interphase -0.4159805729423681 6.265270147542477e-22 BR00117026 SU3327 shuffled compound I20 U2OS 24 278 Interphase -0.4324404321444428 3.5896007323599926e-20 BR00117024 oxibendazole shuffled compound M19 U2OS 24 232 Interphase -0.3816469782571478 1.0379097396094843e-19 BR00117025 thiostrepton shuffled compound B02 U2OS 24 297 Interphase -0.3867295580911223 6.244760377182339e-19 BR00117024 thiostrepton shuffled compound B02 U2OS 24 277 Interphase -0.3794992374173869 1.935743902412613e-18 BR00117026 CYT-997 shuffled compound E06 U2OS 24 280 Interphase -0.3778747177897677 2.8826474395170798e-18 BR00116995 SU3327 shuffled compound I20 U2OS 24 281 Interphase -0.4042083152252644 1.0985125694655548e-17 BR00117024 colchicine shuffled compound K17 U2OS 24 234 Interphase -0.2838639018691589 3.143982858722482e-23 BR00117026 KU-60019 shuffled compound I07 U2OS 24 642 Large -0.43662092624356774 3.7836173271311475e-23 BR00117024 SU3327 shuffled compound I20 U2OS 24 265 Large -0.42312287354232136 1.078304882384493e-22 BR00117026 SU3327 shuffled compound I20 U2OS 24 278 Large -0.2728485202492212 1.884240232083515e-21 BR00117025 KU-60019 shuffled compound I07 U2OS 24 642 Large -0.2761715816174699 1.755396025162558e-20 BR00117026 BMS-536924 shuffled compound B15 U2OS 24 593 Large -0.3638040422671363 2.764032138737706e-18 BR00117026 puromycin shuffled compound C22 U2OS 24 299 Large -0.4200468648998061 4.147974085324624e-18 BR00117024 puromycin shuffled compound C22 U2OS 24 224 Large -0.26481794815494103 1.3569064519157543e-17 BR00117026 PF-431396 shuffled compound L20 U2OS 24 556 Large -0.34249214424659585 1.594749866359137e-17 BR00117024 TG-101348 shuffled compound M20 U2OS 24 328 Large -0.3006814921090387 8.124200222098332e-17 BR00117026 epothilone-b shuffled compound F07 U2OS 24 410 Large -0.41351028216164515 5.416719763244975e-32 BR00117026 epothilone-b shuffled compound F07 U2OS 24 410 Metaphase -0.37970844722113756 1.1494650658908985e-25 BR00117025 epothilone-b shuffled compound F07 U2OS 24 390 Metaphase -0.35637075495786874 9.944289580533625e-22 BR00117024 epothilone-b shuffled compound F07 U2OS 24 372 Metaphase -0.2928530588907947 1.822241505257039e-20 BR00117025 AMG900 shuffled compound N09 U2OS 24 528 Metaphase -0.28502150988522884 8.854837722466597e-19 BR00117025 danusertib shuffled compound N18 U2OS 24 508 Metaphase -0.26827404479578393 6.779552086313876e-18 BR00117025 PF-431396 shuffled compound L20 U2OS 24 550 Metaphase -0.3383206655096056 7.89561465663496e-18 BR00116995 epothilone-b shuffled compound F07 U2OS 24 341 Metaphase -0.23078165374677004 1.519575989536131e-16 BR00117024 KU-60019 shuffled compound I07 U2OS 24 688 Metaphase -0.28857262143208207 1.7480463788953217e-16 BR00117024 AMG900 shuffled compound N09 U2OS 24 433 Metaphase -0.2593647316538883 3.1156120076884184e-15 BR00116995 PF-431396 shuffled compound L20 U2OS 24 498 Metaphase -0.4965624561537775 5.704199399987053e-32 BR00116995 SU3327 shuffled compound I20 U2OS 24 281 MetaphaseAlignment -0.5048599199542596 2.3137620457197637e-31 BR00117024 SU3327 shuffled compound I20 U2OS 24 265 MetaphaseAlignment -0.445445809417448 1.611070193739402e-25 BR00117026 SU3327 shuffled compound I20 U2OS 24 278 MetaphaseAlignment -0.4858948100629903 6.321589866774069e-25 BR00117025 SU3327 shuffled compound I20 U2OS 24 226 MetaphaseAlignment -0.38198757763975155 2.5261271120950336e-21 BR00117026 thiostrepton shuffled compound B02 U2OS 24 322 MetaphaseAlignment -0.37716202927055015 4.40627713542252e-19 BR00117025 delanzomib shuffled compound L11 U2OS 24 295 MetaphaseAlignment -0.36797354747283895 3.993112573494705e-18 BR00117025 CYT-997 shuffled compound C09 U2OS 24 290 MetaphaseAlignment -0.36460651714889003 5.7471649351266644e-18 BR00117025 thiostrepton shuffled compound B02 U2OS 24 297 MetaphaseAlignment -0.3986394557823129 8.76820292816199e-18 BR00117024 NSC-632839 shuffled compound M16 U2OS 24 240 MetaphaseAlignment -0.3699833987720362 2.349660010106494e-17 BR00117024 thiostrepton shuffled compound B02 U2OS 24 277 MetaphaseAlignment -0.28908662092624354 5.965449134036397e-20 BR00117025 AMG900 shuffled compound N09 U2OS 24 528 OutOfFocus -0.29459846414161134 1.5622248020386125e-15 BR00117025 epothilone-b shuffled compound F07 U2OS 24 390 OutOfFocus -0.28767696541549637 3.244445215859495e-14 BR00117024 epothilone-b shuffled compound F07 U2OS 24 372 OutOfFocus -0.23712121212121212 4.54608816537569e-14 BR00117025 PF-431396 shuffled compound L20 U2OS 24 550 OutOfFocus -0.24669784437963055 1.4454965943580932e-13 BR00117026 danusertib shuffled compound E05 U2OS 24 488 OutOfFocus -0.24110471097339015 4.696488427914235e-13 BR00116995 AMG900 shuffled compound N09 U2OS 24 491 OutOfFocus -0.18524753528962162 2.563158499052775e-12 BR00117026 RKI-1447 shuffled compound J04 U2OS 24 786 OutOfFocus -0.22710234878909577 9.310216887806475e-12 BR00116995 PF-431396 shuffled compound L20 U2OS 24 498 OutOfFocus -0.22289156626506024 2.995286190012562e-11 BR00117025 danusertib shuffled compound E05 U2OS 24 498 OutOfFocus -0.23545483852215135 4.306515097149958e-11 BR00117024 AMG900 shuffled compound N09 U2OS 24 433 OutOfFocus -0.14649425787788195 7.711817046203884e-08 BR00117026 RKI-1447 shuffled compound J04 U2OS 24 786 Polylobed -0.1277162818128204 3.901121131021286e-07 BR00117025 NVS-PAK1-1 shuffled compound N14 U2OS 24 940 Polylobed -0.15210038735283454 5.25547514786249e-07 BR00117026 azeliragon shuffled compound C08 U2OS 24 648 Polylobed -0.23205330954408446 5.931089608818784e-07 BR00116995 delanzomib shuffled compound L11 U2OS 24 271 Polylobed -0.13105076741440377 9.312328797472118e-07 BR00117025 RKI-1447 shuffled compound J04 U2OS 24 847 Polylobed -0.21593334474690407 1.5847972390872688e-06 BR00117025 thiostrepton shuffled compound B02 U2OS 24 297 Polylobed -0.12768677957229632 1.592013523242678e-06 BR00117025 AC-710 shuffled compound I03 U2OS 24 856 Polylobed -0.21368895011415961 4.508327835605114e-06 BR00116995 SU3327 shuffled compound I20 U2OS 24 281 Polylobed -0.2090323350435509 4.85356273874674e-06 BR00116995 NSC-632839 shuffled compound M16 U2OS 24 289 Polylobed -0.14572991358705645 6.081515347837863e-06 BR00117025 azeliragon shuffled compound C08 U2OS 24 588 Polylobed -0.3179845093199421 2.6261742479428844e-17 BR00117024 epothilone-b shuffled compound F07 U2OS 24 372 Prometaphase -0.24708404802744424 1.197474130945305e-14 BR00117025 AMG900 shuffled compound N09 U2OS 24 528 Prometaphase -0.28449824287387737 1.6953535371951202e-14 BR00117025 epothilone-b shuffled compound F07 U2OS 24 390 Prometaphase -0.3039166232056291 1.9939925459331424e-14 BR00116995 epothilone-b shuffled compound F07 U2OS 24 341 Prometaphase -0.2534496186989533 2.1331902374611655e-14 BR00116995 AMG900 shuffled compound N09 U2OS 24 491 Prometaphase -0.2650334075723831 2.848343727198693e-14 BR00117026 GSK1070916 shuffled compound C04 U2OS 24 449 Prometaphase -0.23194955660128283 1.5314616367290222e-12 BR00117025 danusertib shuffled compound N18 U2OS 24 508 Prometaphase -0.23468054933572174 1.1589449605768415e-11 BR00117026 UNC2025 shuffled compound N06 U2OS 24 464 Prometaphase -0.28694712760549057 1.1261359307669453e-10 BR00117026 ixabepilone shuffled compound J21 U2OS 24 280 Prometaphase -0.23751793400286944 1.1355846416439933e-10 BR00117026 epothilone-b shuffled compound F07 U2OS 24 410 Prometaphase -0.5300947788308759 3.6749512784952096e-39 BR00117026 puromycin shuffled compound C22 U2OS 24 299 SmallIrregular -0.595 3.2449472294453786e-33 BR00117024 AZD7762 shuffled compound I05 U2OS 24 200 SmallIrregular -0.5011435105774729 6.0433523337711225e-31 BR00117024 SU3327 shuffled compound I20 U2OS 24 265 SmallIrregular -0.48494692655276594 6.50691768914242e-30 BR00117025 puromycin shuffled compound C22 U2OS 24 274 SmallIrregular -0.3495997712978845 3.753136847248794e-29 BR00117025 AMG900 shuffled compound N09 U2OS 24 528 SmallIrregular -0.35943775100401604 5.671747549949098e-29 BR00117025 danusertib shuffled compound E05 U2OS 24 498 SmallIrregular -0.3385815584516229 1.0873067328785602e-28 BR00117026 PF-431396 shuffled compound L20 U2OS 24 556 SmallIrregular -0.336969696969697 3.286222679189794e-28 BR00117025 PF-431396 shuffled compound L20 U2OS 24 550 SmallIrregular -0.4663013271693115 1.1503386087382982e-27 BR00117026 SU3327 shuffled compound I20 U2OS 24 278 SmallIrregular -0.3459907748217863 1.2959140562667753e-27 BR00117025 danusertib shuffled compound N18 U2OS 24 508 SmallIrregular -0.12621950287885536 1.551847021607593e-09 BR00117012 NVS-PAK1-1 shuffled compound N14 U2OS 48 1306 ADCCM -0.10237155526916739 3.1688329406448758e-09 BR00117012 dexamethasone shuffled compound O02 U2OS 48 1916 ADCCM -0.11207276314348505 5.0613950867977954e-09 BR00117011 RKI-1447 shuffled compound J04 U2OS 48 1558 ADCCM -0.09703932183473918 2.121073027713499e-07 BR00117012 methoxsalen shuffled compound M14 U2OS 48 1690 ADCCM -0.12919387075283145 2.2981313724554036e-07 BR00117012 amlodipine shuffled compound A03 U2OS 48 950 ADCCM -0.0984048649388729 2.7652115374952536e-07 BR00117010 RKI-1447 shuffled compound J04 U2OS 48 1612 ADCCM -0.09746182229403706 2.919184766095344e-07 BR00117011 nafamostat shuffled compound I08 U2OS 48 1638 ADCCM -0.10402275497765136 1.6082764804697521e-06 BR00117013 RKI-1447 shuffled compound J04 U2OS 48 1288 ADCCM -0.10262345679012345 2.318618181745668e-06 BR00117010 simvastatin shuffled compound N24 U2OS 48 1296 ADCCM -0.07862722380852645 3.5567912474777415e-06 BR00117012 L-Cystine shuffled compound O08 U2OS 48 2124 ADCCM -0.5993253968253969 2.5776402167481203e-38 BR00117010 delanzomib shuffled compound L11 U2OS 48 224 Anaphase -0.6353846153846154 5.736348206854245e-38 BR00117013 thiostrepton shuffled compound B02 U2OS 48 200 Anaphase -0.23319269375952095 1.1930105848444892e-34 BR00117012 RKI-1447 shuffled compound J04 U2OS 48 1434 Anaphase -0.21870380084887214 2.40335567989507e-34 BR00117010 RKI-1447 shuffled compound J04 U2OS 48 1612 Anaphase -0.5121771217712177 4.6063366538442076e-33 BR00117013 delanzomib shuffled compound L11 U2OS 48 270 Anaphase -0.6163635234961823 1.3220463118494178e-32 BR00117012 thiostrepton shuffled compound B02 U2OS 48 178 Anaphase -0.2287394268615599 2.2471897762480587e-30 BR00117012 NVS-PAK1-1 shuffled compound N14 U2OS 48 1306 Anaphase -0.22880265474739267 4.77137043418293e-30 BR00117013 RKI-1447 shuffled compound J04 U2OS 48 1288 Anaphase -0.5121951219512195 9.190685378691984e-30 BR00117010 AZD7762 shuffled compound K11 U2OS 48 246 Anaphase -0.20660043281526658 1.2218608519575275e-29 BR00117013 NVS-PAK1-1 shuffled compound N14 U2OS 48 1560 Anaphase -0.36418296503457326 7.816739703535689e-87 BR00117012 AC-710 shuffled compound I03 U2OS 48 1462 Apoptosis -0.2920624694559109 1.8246805221458014e-80 BR00117012 L-Cystine shuffled compound O08 U2OS 48 2124 Apoptosis -0.2734386771506338 2.9716619737836506e-62 BR00117012 PETCM shuffled compound I04 U2OS 48 1874 Apoptosis -0.3804752387297357 7.400678813503085e-62 BR00117012 polydatin shuffled compound K08 U2OS 48 950 Apoptosis -0.4396825396825397 4.003722428895275e-55 BR00117012 KU-60019 shuffled compound I07 U2OS 48 630 Apoptosis -0.6422764227642277 4.6116094267741315e-48 BR00117010 AZD7762 shuffled compound K11 U2OS 48 246 Apoptosis -0.5993919292426755 1.0075775260672943e-45 BR00117013 AZD7762 shuffled compound K11 U2OS 48 268 Apoptosis -0.5098658247829518 1.0555207237055585e-43 BR00117013 ganetespib shuffled compound M10 U2OS 48 364 Apoptosis -0.6307142857142857 8.806767182717008e-43 BR00117010 delanzomib shuffled compound L11 U2OS 48 224 Apoptosis -0.3449713065659949 9.519420624921947e-42 BR00117013 KU-60019 shuffled compound I07 U2OS 48 778 Apoptosis -0.19937944132044141 1.8237184942297104e-37 BR00117012 L-Cystine shuffled compound O08 U2OS 48 2124 Binuclear -0.19121719019090141 2.1088064085185083e-23 BR00117012 RKI-1447 shuffled compound J04 U2OS 48 1434 Binuclear -0.29180511943387233 2.599580166731945e-21 BR00117012 fludarabine-phosphate shuffled compound N12 U2OS 48 554 Binuclear -0.1443764857862037 1.525188356690847e-17 BR00117012 PETCM shuffled compound I04 U2OS 48 1874 Binuclear -0.275015318627451 1.5891070950022587e-17 BR00117013 fludarabine-phosphate shuffled compound N12 U2OS 48 510 Binuclear -0.26593409580504646 2.5013765350671995e-17 BR00117011 AMG900 shuffled compound N09 U2OS 48 542 Binuclear -0.1688105784859771 1.0900917999382495e-16 BR00117012 NVS-PAK1-1 shuffled compound N14 U2OS 48 1306 Binuclear -0.19313294232649073 1.1270458389051846e-16 BR00117012 AZ191 shuffled compound I18 U2OS 48 990 Binuclear -0.175901640080948 4.484046390476182e-16 BR00117011 AZ191 shuffled compound I18 U2OS 48 1154 Binuclear -0.2571428571428571 1.217336531334334e-14 BR00117012 AMG900 shuffled compound N09 U2OS 48 490 Binuclear -0.3158645497395187 2.7150166128557595e-31 BR00117011 PF-431396 shuffled compound L20 U2OS 48 696 Elongated -0.3346456692913386 1.3701152074728412e-25 BR00117010 AMG900 shuffled compound N09 U2OS 48 508 Elongated -0.30834067746819427 1.5925557744208115e-25 BR00117010 PF-431396 shuffled compound L20 U2OS 48 596 Elongated -0.31391137115791046 4.494806231045889e-24 BR00117011 AMG900 shuffled compound N09 U2OS 48 542 Elongated -0.290241366099283 6.933362420925532e-23 BR00117013 AMG900 shuffled compound N09 U2OS 48 604 Elongated -0.26002690879571866 3.0622984362067187e-22 BR00117013 PF-431396 shuffled compound L20 U2OS 48 728 Elongated -0.30612244897959184 1.1390024016337636e-20 BR00117012 AMG900 shuffled compound N09 U2OS 48 490 Elongated -0.2587099383277727 5.760794745222363e-19 BR00117010 danusertib shuffled compound E05 U2OS 48 628 Elongated -0.15979045956028257 8.335656825533954e-17 BR00117012 AC-710 shuffled compound I03 U2OS 48 1462 Elongated -0.2735351450521729 1.485363721685573e-15 BR00117013 danusertib shuffled compound N18 U2OS 48 456 Elongated -0.6388354336085418 3.076222173341769e-35 BR00117012 thiostrepton shuffled compound B02 U2OS 48 178 Grape -0.6033333333333334 5.44406747974579e-34 BR00117013 thiostrepton shuffled compound B02 U2OS 48 200 Grape -0.5155425219941349 3.603062476706545e-27 BR00117012 BVT-948 shuffled compound B12 U2OS 48 220 Grape -0.483739837398374 1.9007785863475516e-26 BR00117010 AZD7762 shuffled compound K11 U2OS 48 246 Grape -0.19106170896452226 1.9976579300727044e-25 BR00117013 NVS-PAK1-1 shuffled compound N14 U2OS 48 1560 Grape -0.49234126984126986 2.396910390921166e-25 BR00117010 delanzomib shuffled compound L11 U2OS 48 224 Grape -0.5918367346938775 4.992727513903755e-25 BR00117010 NSC-663284 shuffled compound G06 U2OS 48 154 Grape -0.6029411764705882 2.892810146842966e-24 BR00117010 thiostrepton shuffled compound B02 U2OS 48 144 Grape -0.5839942321557318 4.381521798663614e-24 BR00117012 NSC-632839 shuffled compound M16 U2OS 48 152 Grape -0.4917021378353819 5.0232826643774517e-23 BR00117012 AZD7762 shuffled compound K11 U2OS 48 206 Grape -0.2350440431248512 2.9910887077883465e-12 BR00117012 danusertib shuffled compound N18 U2OS 48 484 Hole -0.18586387434554974 6.0193029782399054e-12 BR00117010 BMS-536924 shuffled compound B15 U2OS 48 764 Hole -0.22379800152350227 6.890916856098464e-12 BR00117011 danusertib shuffled compound E05 U2OS 48 516 Hole -0.20585080181708718 1.1696794804170117e-11 BR00117013 AMG900 shuffled compound N09 U2OS 48 604 Hole -0.12312086500885226 1.3332980788803602e-10 BR00117013 ibudilast shuffled compound G24 U2OS 48 1534 Hole -0.1741480134092993 3.801467491316296e-10 BR00117013 PF-431396 shuffled compound L20 U2OS 48 728 Hole -0.11993056499315193 1.7069583931034774e-09 BR00117013 CP-724714 shuffled compound I16 U2OS 48 1438 Hole -0.09325302595644323 5.905333222428133e-08 BR00117010 4-CMTB shuffled compound C01 U2OS 48 1988 Hole -0.1830708661417323 7.454891961600016e-08 BR00117010 AMG900 shuffled compound N09 U2OS 48 508 Hole -0.23187153931339977 1.1655921676719534e-07 BR00117010 GK921 shuffled compound H24 U2OS 48 300 Hole -0.38006119904801483 9.306353753586123e-34 BR00117012 epothilone-b shuffled compound F07 U2OS 48 514 Interphase -0.3317059821575174 5.257362320616924e-30 BR00117013 AMG900 shuffled compound N09 U2OS 48 604 Interphase -0.21611128586292078 5.269798004321452e-28 BR00117012 PP-2 shuffled compound J10 U2OS 48 1348 Interphase -0.5130769230769231 3.350846927476603e-24 BR00117013 thiostrepton shuffled compound B02 U2OS 48 200 Interphase -0.32040816326530613 1.2237536390626424e-22 BR00117012 AMG900 shuffled compound N09 U2OS 48 490 Interphase -0.30133262658593435 3.3448917471117033e-22 BR00117011 AMG900 shuffled compound N09 U2OS 48 542 Interphase -0.4147547416612165 6.141071105849815e-22 BR00117012 oxibendazole shuffled compound M19 U2OS 48 278 Interphase -0.5054938233285741 1.449060307761302e-21 BR00117012 thiostrepton shuffled compound B02 U2OS 48 178 Interphase -0.37185226121396336 7.368636368217761e-21 BR00117012 briciclib shuffled compound H01 U2OS 48 330 Interphase -0.3881931239481564 9.303366371805206e-21 BR00117010 briciclib shuffled compound H01 U2OS 48 302 Interphase -0.37676488643339473 2.3269398468812994e-23 BR00117012 NVP-HSP990 shuffled compound E23 U2OS 48 360 Large -0.15681788255339305 2.6387149023498542e-23 BR00117012 L-Cystine shuffled compound O08 U2OS 48 2124 Large -0.26539733730257176 3.8072568159096433e-22 BR00117011 PF-431396 shuffled compound L20 U2OS 48 696 Large -0.33770671805673824 5.963405498824547e-22 BR00117011 ixabepilone shuffled compound J21 U2OS 48 424 Large -0.16154095111757513 3.409608063196436e-20 BR00117011 PP-2 shuffled compound J10 U2OS 48 1734 Large -0.33789933488577384 7.778000834001877e-19 BR00117012 GK921 shuffled compound H24 U2OS 48 362 Large -0.34195402298850575 1.967209544437589e-18 BR00117012 ganetespib shuffled compound M10 U2OS 48 348 Large -0.2977598133848134 6.22657055225344e-18 BR00117013 epothilone-b shuffled compound F07 U2OS 48 444 Large -0.303879883072017 6.343734816726876e-18 BR00117011 epothilone-b shuffled compound F07 U2OS 48 426 Large -0.23333233114354865 6.9197948366170266e-18 BR00117013 PF-431396 shuffled compound L20 U2OS 48 728 Large -0.4166824071625552 1.965359192489813e-40 BR00117012 epothilone-b shuffled compound F07 U2OS 48 514 Metaphase -0.38292375896229 5.842945849762438e-40 BR00117013 AMG900 shuffled compound N09 U2OS 48 604 Metaphase -0.41836734693877553 8.408413051647625e-39 BR00117012 AMG900 shuffled compound N09 U2OS 48 490 Metaphase -0.3458917061947461 3.1585184255836587e-38 BR00117012 PF-431396 shuffled compound L20 U2OS 48 712 Metaphase -0.34872240138923344 3.779761134279046e-38 BR00117011 PF-431396 shuffled compound L20 U2OS 48 696 Metaphase -0.3748343560783674 2.2750692152976347e-34 BR00117011 AMG900 shuffled compound N09 U2OS 48 542 Metaphase -0.30472707866688714 2.3190488933918357e-30 BR00117013 PF-431396 shuffled compound L20 U2OS 48 728 Metaphase -0.39519665160775974 4.099078484569948e-30 BR00117011 epothilone-b shuffled compound F07 U2OS 48 426 Metaphase -0.33117528755112646 1.8287154723127345e-29 BR00117010 PF-431396 shuffled compound L20 U2OS 48 596 Metaphase -0.34785478547854787 1.3953668358647068e-27 BR00117010 epothilone-b shuffled compound F07 U2OS 48 504 Metaphase -0.5927742255881805 1.0011866816104389e-29 BR00117012 thiostrepton shuffled compound B02 U2OS 48 178 MetaphaseAlignment -0.20891693212686419 7.57218862138442e-28 BR00117010 PP-2 shuffled compound J10 U2OS 48 1434 MetaphaseAlignment -0.21998785787129943 6.079736337087352e-25 BR00117011 PP-1 shuffled compound A22 U2OS 48 1156 MetaphaseAlignment -0.39320254213871236 2.066368554729054e-23 BR00117012 briciclib shuffled compound H01 U2OS 48 330 MetaphaseAlignment -0.17206275255653136 6.249138257843605e-23 BR00117011 PP-2 shuffled compound J10 U2OS 48 1734 MetaphaseAlignment -0.44715447154471544 1.6292172250433352e-22 BR00117010 AZD7762 shuffled compound K11 U2OS 48 246 MetaphaseAlignment -0.19501294376043754 4.821692379750261e-22 BR00117013 PP-2 shuffled compound J10 U2OS 48 1292 MetaphaseAlignment -0.17641536775522584 2.42773506953584e-21 BR00117012 simvastatin shuffled compound N24 U2OS 48 1538 MetaphaseAlignment -0.4628628820125305 2.002377545448314e-20 BR00117012 AZD7762 shuffled compound K11 U2OS 48 206 MetaphaseAlignment -0.38086378737541526 7.308432925022951e-20 BR00117010 GK921 shuffled compound H24 U2OS 48 300 MetaphaseAlignment -0.31653439877401346 3.2969153954943035e-27 BR00117013 AMG900 shuffled compound N09 U2OS 48 604 OutOfFocus -0.2683163813776565 1.2393511866635863e-22 BR00117011 PF-431396 shuffled compound L20 U2OS 48 696 OutOfFocus -0.18595124689701148 4.1890966649129555e-22 BR00117012 RKI-1447 shuffled compound J04 U2OS 48 1434 OutOfFocus -0.2755905511811024 2.203439796108802e-17 BR00117010 AMG900 shuffled compound N09 U2OS 48 508 OutOfFocus -0.1573709751459112 2.428180019219634e-17 BR00117013 NVS-PAK1-1 shuffled compound N14 U2OS 48 1560 OutOfFocus -0.2320665962777944 2.9114840232091325e-17 BR00117012 PF-431396 shuffled compound L20 U2OS 48 712 OutOfFocus -0.2525026551872189 3.117743696753247e-17 BR00117010 PF-431396 shuffled compound L20 U2OS 48 596 OutOfFocus -0.1540592179853824 3.9737885681944465e-17 BR00117010 RKI-1447 shuffled compound J04 U2OS 48 1612 OutOfFocus -0.16155886754236135 4.485609885986619e-17 BR00117010 NVS-PAK1-1 shuffled compound N14 U2OS 48 1456 OutOfFocus -0.16873222267370988 1.8259086060494634e-16 BR00117013 RKI-1447 shuffled compound J04 U2OS 48 1288 OutOfFocus -0.1474451113521747 7.92969523247277e-13 BR00117012 NVS-PAK1-1 shuffled compound N14 U2OS 48 1306 Polylobed -0.1134263592274313 7.130017751425291e-10 BR00117013 AC-710 shuffled compound I03 U2OS 48 1680 Polylobed -0.10761714406516744 4.691672395823404e-09 BR00117013 FERb-033 shuffled compound N20 U2OS 48 1708 Polylobed -0.113874583883875 9.714201547391095e-09 BR00117012 AC-710 shuffled compound I03 U2OS 48 1462 Polylobed -0.25194250194250195 1.477925276870534e-08 BR00117012 geldanamycin shuffled compound L01 U2OS 48 288 Polylobed -0.10034802784222738 5.637411979782581e-08 BR00117013 GNF-5 shuffled compound B09 U2OS 48 1724 Polylobed -0.10345141104245975 6.950573217678878e-08 BR00117011 NVS-PAK1-1 shuffled compound N14 U2OS 48 1590 Polylobed -0.10056355181966342 7.020895137903754e-08 BR00117013 afimoxifene shuffled compound K18 U2OS 48 1686 Polylobed -0.10638297872340426 7.893099058437012e-08 BR00117011 TCN201 shuffled compound B21 U2OS 48 1504 Polylobed -0.10767260510688315 1.094968133204717e-07 BR00117012 RKI-1447 shuffled compound J04 U2OS 48 1434 Polylobed -0.3464566929133858 1.9502554207619643e-27 BR00117010 AMG900 shuffled compound N09 U2OS 48 508 Prometaphase -0.2808566939551807 1.3437432561603748e-24 BR00117011 PF-431396 shuffled compound L20 U2OS 48 696 Prometaphase -0.29833616112965905 3.579114875639535e-24 BR00117013 AMG900 shuffled compound N09 U2OS 48 604 Prometaphase -0.3306122448979592 4.1903712505659835e-24 BR00117012 AMG900 shuffled compound N09 U2OS 48 490 Prometaphase -0.3121309113643623 8.591794715027235e-24 BR00117011 AMG900 shuffled compound N09 U2OS 48 542 Prometaphase -0.323943661971831 3.594274090168571e-20 BR00117010 GSK1070916 shuffled compound C04 U2OS 48 426 Prometaphase -0.14646946946147024 1.1800861493179705e-16 BR00117011 PP-2 shuffled compound J10 U2OS 48 1734 Prometaphase -0.255736466321635 2.2711281186093406e-15 BR00117012 epothilone-b shuffled compound F07 U2OS 48 514 Prometaphase -0.27431225868725867 2.6049768166151747e-15 BR00117013 epothilone-b shuffled compound F07 U2OS 48 444 Prometaphase -0.3462916939175932 2.641925010963455e-15 BR00117012 oxibendazole shuffled compound M19 U2OS 48 278 Prometaphase -0.4377940800649419 2.8336623730187687e-63 BR00117013 PF-431396 shuffled compound L20 U2OS 48 728 SmallIrregular -0.4592558891921949 2.889806124181938e-60 BR00117010 danusertib shuffled compound E05 U2OS 48 628 SmallIrregular -0.43707771224549746 9.676216815803225e-52 BR00117010 PF-431396 shuffled compound L20 U2OS 48 596 SmallIrregular -0.26459896443695347 1.6665426451308248e-45 BR00117012 AC-710 shuffled compound I03 U2OS 48 1462 SmallIrregular -0.4239456377652797 2.2238904077319082e-45 BR00117010 danusertib shuffled compound N18 U2OS 48 556 SmallIrregular -0.37903332506408666 3.391348218945651e-45 BR00117011 PF-431396 shuffled compound L20 U2OS 48 696 SmallIrregular -0.42489109973972666 1.8300068520872418e-44 BR00117011 AMG900 shuffled compound N09 U2OS 48 542 SmallIrregular -0.44693877551020406 1.9892130320537737e-44 BR00117012 AMG900 shuffled compound N09 U2OS 48 490 SmallIrregular -0.43679216406489135 5.1234438555795e-42 BR00117012 danusertib shuffled compound N18 U2OS 48 484 SmallIrregular -0.42948296593186375 5.4254051415213464e-42 BR00117012 danusertib shuffled compound E05 U2OS 48 500 SmallIrregular -0.08383018678894039 3.9342687249448214e-06 BR00118043 UGT1A9 shuffled crispr J01 A549 96 1854 ADCCM -0.07940228319097001 1.8678318874554037e-05 BR00118043 GJB4 shuffled crispr N01 A549 96 1829 ADCCM -0.13343799058084774 2.313867434536494e-05 BR00118042 HTR3A shuffled crispr O02 A549 96 637 ADCCM -0.07311292411788778 2.394305169399945e-05 BR00118041 CDK2 shuffled crispr L19 A549 96 2107 ADCCM -0.15444483751958357 6.867280346185036e-05 BR00118042 CACNA2D3 shuffled crispr O07 A549 96 423 ADCCM -0.07417301003835843 6.8732953161773e-05 BR00118043 LPAR1 shuffled crispr L01 A549 96 1855 ADCCM -0.10621468926553672 9.103914255537192e-05 BR00118043 HIF1A shuffled crispr A01 A549 96 885 ADCCM -0.07786994815789514 9.252745328988362e-05 BR00118041 NTRK1 shuffled crispr P07 A549 96 1637 ADCCM -0.14473684210526316 0.0001387909311146069 BR00118042 BRD4 shuffled crispr M19 A549 96 456 ADCCM -0.07269880195560832 0.00017409621442366166 BR00118043 HSD11B1 shuffled crispr O01 A549 96 1752 ADCCM -0.11662917118554438 2.8580815515917762e-11 BR00118043 GJB4 shuffled crispr N01 A549 96 1829 Anaphase -0.11732152739346983 3.0010836572915955e-11 BR00118044 HSD11B1 shuffled crispr O01 A549 96 1807 Anaphase -0.1222794045492141 6.53725025495505e-11 BR00118044 OPRM1 shuffled crispr P22 A549 96 1604 Anaphase -0.11513352344699011 7.594143793553579e-11 BR00118041 KRAS shuffled crispr F07 A549 96 1797 Anaphase -0.11351663433495651 3.1848343509530575e-10 BR00118044 LPAR1 shuffled crispr L01 A549 96 1740 Anaphase -0.12159408771806798 1.0130473745403774e-09 BR00118043 BTK shuffled crispr P17 A549 96 1434 Anaphase -0.1066405373662193 4.532137501508476e-09 BR00118044 GJB4 shuffled crispr N01 A549 96 1740 Anaphase -0.1094785728883429 5.792538567695922e-09 BR00118043 SCNN1G shuffled crispr P15 A549 96 1623 Anaphase -0.10227084745841691 6.7262633073244855e-09 BR00118043 UGT1A9 shuffled crispr J01 A549 96 1854 Anaphase -0.112532110730862 7.743484224290533e-09 BR00118044 HCK shuffled crispr H23 A549 96 1515 Anaphase -0.10183439983925927 1.6287343409786436e-14 BR00118041 UGT1A9 shuffled crispr J01 A549 96 3112 Apoptosis -0.29362710750092996 2.1854619396924809e-13 BR00118042 PPAT shuffled crispr E13 A549 96 339 Apoptosis -0.2106969205834684 2.1168187696852696e-12 BR00118044 FOXM1 shuffled crispr A19 A549 96 617 Apoptosis -0.11541072028603722 3.254789327842253e-11 BR00118043 LPAR1 shuffled crispr L01 A549 96 1855 Apoptosis -0.19371458011334364 3.972977923970561e-11 BR00118044 PPAT shuffled crispr E13 A549 96 647 Apoptosis -0.11263467482968699 4.473931229469932e-11 BR00118043 ELANE shuffled crispr N19 A549 96 1915 Apoptosis -0.31906434052356797 5.6455489765326694e-11 BR00118043 RPL23A shuffled crispr M18 A549 96 233 Apoptosis -0.09051603270052559 3.180440347401506e-10 BR00118041 LYN shuffled crispr N13 A549 96 2739 Apoptosis -0.2710188261351052 3.612882590247652e-10 BR00118043 RPL23A shuffled crispr G14 A549 96 301 Apoptosis -0.23639020825721593 3.8719450313383793e-10 BR00118044 RPL23A shuffled crispr G14 A549 96 391 Apoptosis -0.12526534912909654 3.589774348778253e-16 BR00118044 PTK2B shuffled crispr N15 A549 96 2302 Binuclear -0.3880311391041005 3.9435913295252796e-16 BR00118043 RPL23A shuffled crispr M18 A549 96 233 Binuclear -0.3338180221950918 6.29830720153254e-14 BR00118043 RPL3 shuffled crispr K04 A549 96 269 Binuclear -0.3109856035437431 2.6975809099644475e-13 BR00118043 RPL23A shuffled crispr G14 A549 96 301 Binuclear -0.1253983334677793 5.741559972083494e-13 BR00118043 GJB4 shuffled crispr N01 A549 96 1829 Binuclear -0.33030024509803924 8.915901877549556e-13 BR00118041 AURKB shuffled crispr C13 A549 96 255 Binuclear -0.1725926113168438 4.548412643780221e-12 BR00118041 TUBB4B shuffled crispr C04 A549 96 890 Binuclear -0.23908537774083993 1.2574887216012017e-11 BR00118044 RPL3 shuffled crispr K04 A549 96 441 Binuclear -0.11704135349829736 1.5895345541329588e-11 BR00118043 LPAR1 shuffled crispr L01 A549 96 1855 Binuclear -0.2053294402444959 5.873913415271536e-11 BR00118041 TGFBR1 shuffled crispr P24 A549 96 569 Binuclear -0.16917706334820845 3.921837749785342e-07 BR00118044 AURKB shuffled crispr C13 A549 96 533 Elongated -0.1956241956241956 7.546163863520574e-05 BR00118042 PLD1 shuffled crispr F11 A549 96 259 Elongated -0.2467948717948718 0.00012591295147256593 BR00118042 AURKB shuffled crispr C13 A549 96 152 Elongated -0.1782178217821782 0.00012766542630860786 BR00118044 PLK1 shuffled crispr F13 A549 96 303 Elongated -0.18209420382984193 0.0004185681974008967 BR00118043 PLK1 shuffled crispr G09 A549 96 251 Elongated -0.110260494712391 0.0004660208812002701 BR00118043 S1PR1 shuffled crispr P23 A549 96 682 Elongated -0.10520990826105243 0.0005933557809613958 BR00118043 GHSR shuffled crispr A09 A549 96 726 Elongated -0.15606213915838343 0.0007187869993442409 BR00118042 FLT3 shuffled crispr G16 A549 96 318 Elongated -0.05497548560329834 0.000747336104244894 BR00118041 RGS4 shuffled crispr N11 A549 96 2591 Elongated -0.09544249354418026 0.000895256946008437 BR00118043 TUBB shuffled crispr K13 A549 96 833 Elongated -0.13295104353312096 1.957830869236066e-24 BR00118041 UGT1A9 shuffled crispr J01 A549 96 3112 Grape -0.16768123962368567 1.3716989058260737e-22 BR00118044 HSD11B1 shuffled crispr O01 A549 96 1807 Grape -0.16985799087540362 1.209646381799742e-20 BR00118044 OPRM1 shuffled crispr P22 A549 96 1604 Grape -0.1360933477750462 2.2292204779303273e-20 BR00118041 AKR1B1 shuffled crispr L21 A549 96 2467 Grape -0.14009717238837416 3.245226985788992e-20 BR00118044 PTK2B shuffled crispr N15 A549 96 2302 Grape -0.127270170796574 7.91833352398367e-20 BR00118041 LYN shuffled crispr N13 A549 96 2739 Grape -0.1492497723583673 2.3483275494768402e-17 BR00118044 LPAR1 shuffled crispr L01 A549 96 1740 Grape -0.11646568875071134 4.6510729121470466e-17 BR00118041 MAPK8 shuffled crispr D07 A549 96 2807 Grape -0.14520464129735094 5.01775264822065e-17 BR00118041 KRAS shuffled crispr F07 A549 96 1797 Grape -0.14670333050627737 6.070692657592917e-16 BR00118044 CACNG1 shuffled crispr N23 A549 96 1653 Grape -0.2301182533572834 1.4559512504186999e-10 BR00118042 PLA2G1B shuffled crispr J11 A549 96 432 Hole -0.10973475810077117 2.0697297183478983e-09 BR00118044 AKT1 shuffled crispr J19 A549 96 1700 Hole -0.16040481317637995 4.970790308026798e-09 BR00118041 CDC25A shuffled crispr C14 A549 96 764 Hole -0.14124293785310735 4.093319079334827e-08 BR00118043 HIF1A shuffled crispr A01 A549 96 885 Hole -0.15827338129496402 5.1706992383813e-08 BR00118042 PPARD shuffled crispr E05 A549 96 695 Hole -0.11727078891257996 4.884472566508984e-06 BR00118041 MAPK14 shuffled crispr A20 A549 96 938 Hole -0.21847595103409057 6.886421987008993e-06 BR00118042 BRD4 shuffled crispr J16 A549 96 259 Hole -0.1196439306990217 8.95192333790628e-06 BR00118044 ADA shuffled crispr O24 A549 96 855 Hole -0.10674795509725046 1.0355014479277664e-05 BR00118044 ADH1C shuffled crispr D02 A549 96 1055 Hole -0.1256544502617801 1.1266558551243533e-05 BR00118042 JAK1 shuffled crispr M21 A549 96 764 Hole -0.12451577199778639 1.2751756412880374e-12 BR00118044 HSD11B1 shuffled crispr O01 A549 96 1807 Interphase -0.1328753956986782 7.941626238514109e-08 BR00118044 SSTR2 shuffled crispr P10 A549 96 953 Interphase -0.08901475871264028 1.268322182772054e-07 BR00118041 AKT1 shuffled crispr J19 A549 96 2080 Interphase -0.09401309343754917 1.2537860145536852e-06 BR00118044 OPRM1 shuffled crispr P22 A549 96 1604 Interphase -0.0753435609789481 1.5192933374061077e-06 BR00118041 AKR1B1 shuffled crispr L21 A549 96 2467 Interphase -0.11693029066763325 1.5602421800610165e-06 BR00118044 HIF1A shuffled crispr A01 A549 96 1021 Interphase -0.09144810288083743 1.7051772003835682e-06 BR00118044 BTK shuffled crispr P17 A549 96 1662 Interphase -0.23226449042539518 2.0473912619526826e-06 BR00118043 PLK1 shuffled crispr G09 A549 96 251 Interphase -0.10951296852765958 2.370548914917854e-06 BR00118044 P2RY12 shuffled crispr P19 A549 96 1129 Interphase -0.1374532427164006 2.7831229906883687e-06 BR00118044 FFAR2 shuffled crispr A24 A549 96 703 Interphase -0.1015173180229336 8.505597010621602e-09 BR00118043 LPAR1 shuffled crispr L01 A549 96 1855 Large -0.08541078478418401 1.0853612188145383e-08 BR00118041 RGS4 shuffled crispr N11 A549 96 2591 Large -0.2768890622967876 2.1098396129184874e-08 BR00118043 RPL23A shuffled crispr M18 A549 96 233 Large -0.21106647643968732 3.85971683268253e-08 BR00118041 CA5A shuffled crispr M01 A549 96 389 Large -0.07816186168984672 9.908367884290529e-08 BR00118041 LYN shuffled crispr N13 A549 96 2739 Large -0.09545253590779638 1.0848424234528682e-07 BR00118044 AKR1B1 shuffled crispr H17 A549 96 1818 Large -0.09272421705121804 1.2574035892823857e-07 BR00118043 ELANE shuffled crispr N19 A549 96 1915 Large -0.08440469557140934 1.4347940364006263e-07 BR00118044 PTK2B shuffled crispr N15 A549 96 2302 Large -0.1389605248275082 1.546524990014342e-07 BR00118041 KCNN4 shuffled crispr A22 A549 96 840 Large -0.094238661164964 2.2959578691914285e-07 BR00118044 SLC29A1 shuffled crispr N21 A549 96 1789 Large -0.10364034215237716 2.8412802992042273e-13 BR00118041 LYN shuffled crispr N13 A549 96 2739 Metaphase -0.22740907982743452 1.4998911963767713e-12 BR00118044 AURKB shuffled crispr C13 A549 96 533 Metaphase -0.08819645946923872 5.9915090025761e-10 BR00118041 MAPK8 shuffled crispr D07 A549 96 2807 Metaphase -0.08349463908166109 6.762611151017012e-10 BR00118041 UGT1A9 shuffled crispr J01 A549 96 3112 Metaphase -0.08441631871955463 6.890836600691855e-08 BR00118041 CACNG1 shuffled crispr L02 A549 96 2400 Metaphase -0.07712595630178676 8.436487076948066e-08 BR00118041 FOXM1 shuffled crispr F23 A549 96 2840 Metaphase -0.09914324091936445 1.5126745193331198e-07 BR00118044 CACNG1 shuffled crispr N23 A549 96 1653 Metaphase -0.07658548271276258 4.5373085905504493e-07 BR00118041 RGS4 shuffled crispr N11 A549 96 2591 Metaphase -0.08862688285574753 5.02616341961094e-07 BR00118043 ELANE shuffled crispr N19 A549 96 1915 Metaphase -0.08000745448557448 7.498164771377942e-07 BR00118044 PTK2B shuffled crispr N15 A549 96 2302 Metaphase -0.09739900387382401 7.02279605278646e-08 BR00118044 HSD11B1 shuffled crispr O01 A549 96 1807 MetaphaseAlignment -0.09091802681150978 5.141366452498071e-07 BR00118043 GJB4 shuffled crispr N01 A549 96 1829 MetaphaseAlignment -0.134610450563204 7.986791309984772e-07 BR00118041 CHRM3 shuffled crispr B21 A549 96 800 MetaphaseAlignment -0.10430168085668604 9.066997040162471e-07 BR00118043 TGFBR1 shuffled crispr P24 A549 96 1336 MetaphaseAlignment -0.08944468638241156 1.6580155127395254e-06 BR00118044 GJB4 shuffled crispr N01 A549 96 1740 MetaphaseAlignment -0.0888692772683963 1.8060289741726762e-06 BR00118043 HSD11B1 shuffled crispr O01 A549 96 1752 MetaphaseAlignment -0.13777777777777778 5.280667984752215e-06 BR00118042 PAK4 shuffled crispr G22 A549 96 675 MetaphaseAlignment -0.15199471421050587 7.951830807587293e-06 BR00118041 HDAC3 shuffled crispr K19 A549 96 531 MetaphaseAlignment -0.2172111672111672 8.21244327927501e-06 BR00118042 PDPK1 shuffled crispr N18 A549 96 260 MetaphaseAlignment -0.10690633869441817 1.1143652757572992e-05 BR00118041 CSF1R shuffled crispr C08 A549 96 1057 MetaphaseAlignment -0.17335207252860366 2.746964833025131e-23 BR00118044 LPAR1 shuffled crispr L01 A549 96 1740 OutOfFocus -0.1478508182391947 2.2366718120196595e-22 BR00118044 PTK2B shuffled crispr N15 A549 96 2302 OutOfFocus -0.16195943360122464 2.1437426586112222e-20 BR00118044 GJB4 shuffled crispr N01 A549 96 1740 OutOfFocus -0.15439955727725513 3.3335585316213484e-19 BR00118044 HSD11B1 shuffled crispr O01 A549 96 1807 OutOfFocus -0.16007105724568582 5.735619518127498e-19 BR00118044 CACNG1 shuffled crispr N23 A549 96 1653 OutOfFocus -0.15809151812360628 1.954563337953849e-18 BR00118044 AKR1B1 shuffled crispr L21 A549 96 1649 OutOfFocus -0.11919010835464396 1.9449551780135367e-17 BR00118041 LYN shuffled crispr N13 A549 96 2739 OutOfFocus -0.161025666413633 3.716388385204793e-17 BR00118044 KCNQ2 shuffled crispr P13 A549 96 1476 OutOfFocus -0.15492152512723317 1.3509389091224827e-16 BR00118044 UGT1A9 shuffled crispr J01 A549 96 1538 OutOfFocus -0.14233254757145802 1.3742002960451109e-16 BR00118043 GJB4 shuffled crispr N01 A549 96 1829 OutOfFocus -0.10015492616799807 7.341476100141344e-08 BR00118044 AKT1 shuffled crispr J19 A549 96 1700 Polylobed -0.1553956834532374 9.728939191774991e-08 BR00118042 PPARD shuffled crispr E05 A549 96 695 Polylobed -0.09816116549867152 1.8564513333364291e-07 BR00118043 RGS4 shuffled crispr N11 A549 96 1674 Polylobed -0.09801659187446748 3.689975482919408e-07 BR00118044 OPRM1 shuffled crispr P22 A549 96 1604 Polylobed -0.09158328716631159 5.054587741503703e-07 BR00118044 GUCY1B1 shuffled crispr H21 A549 96 1796 Polylobed -0.08982781955561132 7.382213474734401e-07 BR00118043 GJB4 shuffled crispr N01 A549 96 1829 Polylobed -0.08935510898813369 3.1840463355599053e-06 BR00118044 CACNG1 shuffled crispr N23 A549 96 1653 Polylobed -0.13052197783296984 3.906196348528279e-06 BR00118041 CDC25A shuffled crispr C14 A549 96 764 Polylobed -0.0790486926410133 4.227313931074099e-06 BR00118041 AKT1 shuffled crispr J19 A549 96 2080 Polylobed -0.08436256183095465 5.334917188643468e-06 BR00118044 SLC29A1 shuffled crispr N21 A549 96 1789 Polylobed -0.274984681372549 5.749781331498082e-09 BR00118041 AURKB shuffled crispr C13 A549 96 255 Prometaphase -0.18492136681471116 1.8313532051338436e-08 BR00118044 AURKB shuffled crispr C13 A549 96 533 Prometaphase -0.31713900134952766 2.29344901459605e-07 BR00118042 AURKB shuffled crispr C13 A549 96 152 Prometaphase -0.20079111990133225 8.115125110855418e-06 BR00118044 PLK1 shuffled crispr G09 A549 96 301 Prometaphase -0.1256544502617801 1.1266558551243533e-05 BR00118042 JAK1 shuffled crispr M21 A549 96 764 Prometaphase -0.19801980198019803 1.304697785728726e-05 BR00118044 PLK1 shuffled crispr F13 A549 96 303 Prometaphase -0.11907654921020656 1.6752681492720263e-05 BR00118041 PAK1 shuffled crispr K10 A549 96 823 Prometaphase -0.13992510180337406 2.2359170880916605e-05 BR00118042 AKR1B1 shuffled crispr L21 A549 96 576 Prometaphase -0.11171762603240996 3.639861636965275e-05 BR00118042 PDE3A shuffled crispr O08 A549 96 861 Prometaphase -0.13703486740135956 3.804785885563771e-05 BR00118042 SLC29A1 shuffled crispr E03 A549 96 573 Prometaphase -0.28976796938764693 2.7584515937958454e-20 BR00118044 AURKB shuffled crispr C13 A549 96 533 SmallIrregular -0.41346153846153844 2.603290784039161e-12 BR00118042 AURKB shuffled crispr C13 A549 96 152 SmallIrregular -0.11430577169139261 4.143054224355148e-10 BR00118044 AKT1 shuffled crispr J19 A549 96 1700 SmallIrregular -0.11317837031345099 1.192231228024517e-09 BR00118044 AKR1B1 shuffled crispr L21 A549 96 1649 SmallIrregular -0.11100956229040142 4.523441176678485e-09 BR00118044 OPRM1 shuffled crispr P22 A549 96 1604 SmallIrregular -0.09963713846850608 9.342031975928289e-09 BR00118043 ELANE shuffled crispr N19 A549 96 1915 SmallIrregular -0.17530790062754353 2.8365935412384277e-08 BR00118043 AURKB shuffled crispr C13 A549 96 577 SmallIrregular -0.09928450411661108 3.840561917078234e-08 BR00118044 GUCY1B1 shuffled crispr H21 A549 96 1796 SmallIrregular -0.10384066111096597 1.5028577905903372e-07 BR00118044 HCK shuffled crispr H23 A549 96 1515 SmallIrregular -0.09903155023737016 1.5247456644515235e-07 BR00118044 CACNG1 shuffled crispr N23 A549 96 1653 SmallIrregular -0.0797005458533848 1.937587997013754e-06 BR00117005 CSK shuffled crispr B05 A549 144 2170 ADCCM -0.09375957795588401 1.083088676259299e-05 BR00117005 TUBB4B shuffled crispr J13 A549 144 1370 ADCCM -0.09434380840917428 1.4655806777916096e-05 BR00117005 CHRM3 shuffled crispr B17 A549 144 1311 ADCCM -0.06658308322148991 2.9534147543389377e-05 BR00117005 PTK2B shuffled crispr N15 A549 144 2494 ADCCM -0.06725629633451702 4.749071097143164e-05 BR00117003 GAA shuffled crispr L17 A549 144 2330 ADCCM -0.08800149801444579 6.530091429682461e-05 BR00117005 RGS4 shuffled crispr E08 A549 144 1324 ADCCM -0.06507516602582877 7.288292639079618e-05 BR00117004 CDK2 shuffled crispr L19 A549 144 2403 ADCCM -0.08111401218450827 7.586829613270148e-05 BR00117004 TNF shuffled crispr I10 A549 144 1532 ADCCM -0.18946143805686397 0.00011683736781609133 BR00117002 PTPN2 shuffled crispr B12 A549 144 268 ADCCM -0.15520005088734815 0.0001192892923719953 BR00117002 CSK shuffled crispr B11 A549 144 398 ADCCM -0.11391821239741323 2.140019449290871e-14 BR00117005 LPAR1 shuffled crispr L01 A549 144 2470 Anaphase -0.11530506958148272 9.964015770667056e-14 BR00117001 CACNA2D3 shuffled crispr O07 A549 144 2289 Anaphase -0.11224267480221752 5.279725975126395e-10 BR00117001 LPAR1 shuffled crispr L01 A549 144 1739 Anaphase -0.1055909933958503 1.7817647447690346e-09 BR00117001 SLC29A1 shuffled crispr N21 A549 144 1860 Anaphase -0.08786565181121908 3.87830220546278e-08 BR00117005 PDPK1 shuffled crispr N18 A549 144 2282 Anaphase -0.09194508657704016 5.753784731497302e-08 BR00117003 LYN shuffled crispr N13 A549 144 2038 Anaphase -0.09394904458598727 1.176030489163364e-07 BR00117003 BTK shuffled crispr P17 A549 144 1884 Anaphase -0.08684891908186555 2.303944404793844e-07 BR00117004 IGF1R shuffled crispr M22 A549 144 2111 Anaphase -0.15221934043209473 2.64523422983672e-07 BR00117001 SIRT2 shuffled crispr P01 A549 144 679 Anaphase -0.09101397897861224 3.831480690170291e-07 BR00117004 AVPR1A shuffled crispr J07 A549 144 1852 Anaphase -0.14898767881937122 1.4182723943443798e-24 BR00117005 PTK2B shuffled crispr N15 A549 144 2494 Apoptosis -0.11889752351293031 2.528697584277952e-20 BR00117004 AKT1 shuffled crispr J19 A549 144 3225 Apoptosis -0.31351351351351353 1.8186969104771737e-16 BR00117003 PPAT shuffled crispr E13 A549 144 370 Apoptosis -0.45489099254159493 4.4404672009575394e-16 BR00117000 RPL23A shuffled crispr M18 A549 144 166 Apoptosis -0.220230777610059 1.0759296092743077e-15 BR00117000 PPAT shuffled crispr E13 A549 144 716 Apoptosis -0.11457131872356786 2.7764865770551965e-15 BR00117004 F10 shuffled crispr H15 A549 144 2601 Apoptosis -0.241811218888444 7.505294583811912e-15 BR00117003 FOXM1 shuffled crispr A19 A549 144 557 Apoptosis -0.3003414028553693 9.50922831430044e-15 BR00117000 RPL23A shuffled crispr G14 A549 144 358 Apoptosis -0.2706422018348624 1.8772397815487437e-14 BR00117004 CDK7 shuffled crispr I14 A549 144 436 Apoptosis -0.279088595882489 4.958021681555965e-14 BR00117000 AURKB shuffled crispr C13 A549 144 396 Apoptosis -0.14671452001107585 1.2598608006931181e-23 BR00117005 LPAR1 shuffled crispr L01 A549 144 2470 Binuclear -0.5222317842799771 1.5405556487929034e-21 BR00117000 RPL23A shuffled crispr M18 A549 144 166 Binuclear -0.13904281556345427 1.737288606257629e-21 BR00117005 PTK2B shuffled crispr N15 A549 144 2494 Binuclear -0.13216406276483222 6.424192677403777e-18 BR00117001 CACNA2D3 shuffled crispr O07 A549 144 2289 Binuclear -0.32364005880826774 7.146093531350325e-18 BR00117000 RPL3 shuffled crispr K04 A549 144 372 Binuclear -0.27897838899803534 7.649719843858138e-18 BR00117000 TUBB3 shuffled crispr K11 A549 144 509 Binuclear -0.11855291993595785 3.1509668499550514e-17 BR00117003 PORCN shuffled crispr L13 A549 144 2737 Binuclear -0.3227498448168839 5.3392890431697105e-17 BR00117000 RPL23A shuffled crispr G14 A549 144 358 Binuclear -0.2714927471623058 3.0738860598722235e-16 BR00117003 FFAR2 shuffled crispr A24 A549 144 482 Binuclear -0.12027230455290536 3.229390383607896e-16 BR00117003 AKT1 shuffled crispr J19 A549 144 2505 Binuclear -0.21289228159457166 2.473930842984745e-08 BR00117000 AURKB shuffled crispr C13 A549 144 396 Elongated -0.19734111244350153 1.6554943361245444e-05 BR00117000 PLK1 shuffled crispr G09 A549 144 293 Elongated -0.18140871255334431 1.8762510195943396e-05 BR00117001 PLK1 shuffled crispr G09 A549 144 345 Elongated -0.26288288288288286 4.534769399493828e-05 BR00117005 AURKB shuffled crispr C13 A549 144 150 Elongated -0.12498992179311456 9.256678196356475e-05 BR00117004 IL1B shuffled crispr H18 A549 144 628 Elongated -0.0850115482799141 0.00011719127739021272 BR00117004 P3H1 shuffled crispr I01 A549 144 1334 Elongated -0.2820089955022489 0.00013273081390235205 BR00117002 AURKB shuffled crispr C13 A549 144 115 Elongated -0.13857267044748933 0.00013703669159126477 BR00117002 HTR2C shuffled crispr M12 A549 144 493 Elongated -0.0951931663100433 0.0002630879921428122 BR00117005 ADA shuffled crispr O06 A549 144 973 Elongated -0.1367440506513354 0.00034973962375316273 BR00117004 ATP5F1D shuffled crispr E15 A549 144 453 Elongated -0.16175252325000772 1.1803106642133623e-26 BR00117001 CACNA2D3 shuffled crispr O07 A549 144 2289 Grape -0.16800304224883456 6.626108436272686e-22 BR00117001 LPAR1 shuffled crispr L01 A549 144 1739 Grape -0.12014696482552133 9.158704516907014e-21 BR00117004 AKT1 shuffled crispr J19 A549 144 3225 Grape -0.1546593402818606 1.2090848740312405e-18 BR00117001 CACNG1 shuffled crispr N23 A549 144 1738 Grape -0.14002848509010649 2.1704532715023554e-16 BR00117001 SLC29A1 shuffled crispr N21 A549 144 1860 Grape -0.14610485341002347 6.791890529493172e-16 BR00117001 HPGDS shuffled crispr P14 A549 144 1659 Grape -0.10741485335856196 1.2341997403246362e-15 BR00117004 AKR1B1 shuffled crispr L21 A549 144 3024 Grape -0.14521687060072988 1.6609965783865402e-15 BR00117001 PTK2B shuffled crispr N15 A549 144 1629 Grape -0.1386018237082067 3.441318892636422e-14 BR00117001 RGS4 shuffled crispr N11 A549 144 1645 Grape -0.1537290715372907 5.838876090084587e-14 BR00117001 GJB4 shuffled crispr N01 A549 144 1314 Grape -0.13346228239845262 1.9154378144263854e-08 BR00117005 PDE3A shuffled crispr O08 A549 144 1034 Hole -0.17694277553432483 2.8017456432727274e-08 BR00117001 CA5A shuffled crispr M01 A549 144 572 Hole -0.12205902373821134 7.888693139325243e-08 BR00117001 FFAR4 shuffled crispr E04 A549 144 1138 Hole -0.1290451176400107 2.500189179831361e-07 BR00117005 GLRA3 shuffled crispr F16 A549 144 947 Hole -0.12768170886476288 1.33121835691432e-06 BR00117005 BRD4 shuffled crispr J16 A549 144 861 Hole -0.1369472182596291 3.7802155467799934e-06 BR00117005 HSP90AB1 shuffled crispr B10 A549 144 701 Hole -0.11488595775796609 5.544862810915545e-06 BR00117005 KCNK1 shuffled crispr C17 A549 144 962 Hole -0.17691622670313592 6.643221802520461e-06 BR00117002 CSK shuffled crispr B11 A549 144 398 Hole -0.07241788850536542 7.187014758162492e-06 BR00117004 EZH2 shuffled crispr H09 A549 144 2374 Hole -0.22107477529164277 7.383259026452068e-06 BR00117002 FLT3 shuffled crispr J20 A549 144 249 Hole -0.2776727239184577 1.5026294011418416e-10 BR00117000 PLK1 shuffled crispr G09 A549 144 293 Interphase -0.14403425088608435 6.773197234270607e-10 BR00117005 GJB4 shuffled crispr N01 A549 144 1041 Interphase -0.21208335361467612 5.240670796038631e-09 BR00117002 OPRM1 shuffled crispr P22 A549 144 431 Interphase -0.21884879327627418 9.260907128355736e-09 BR00117000 AURKB shuffled crispr C13 A549 144 396 Interphase -0.08895106157609857 2.3982061546818463e-08 BR00117001 CACNA2D3 shuffled crispr O07 A549 144 2289 Interphase -0.08808895235654174 2.64426771948676e-07 BR00117004 GPR119 shuffled crispr P21 A549 144 2025 Interphase -0.26560925945772157 2.984303284294108e-07 BR00117000 PLK1 shuffled crispr F13 A549 144 217 Interphase -0.07735566353142516 2.0861965080284185e-06 BR00117005 PDPK1 shuffled crispr N18 A549 144 2282 Interphase -0.061589603848575286 8.75903481976451e-06 BR00117004 AKT1 shuffled crispr J19 A549 144 3225 Interphase -0.12344139650872818 9.6254152869784e-06 BR00117002 BRAF shuffled crispr J10 A549 144 802 Interphase -0.10543847087756436 2.0706949840485905e-12 BR00117005 LPAR1 shuffled crispr L01 A549 144 2470 Large -0.25610424053734615 3.560613832200927e-11 BR00117000 RPL3 shuffled crispr K04 A549 144 372 Large -0.09510259387685001 2.8797050125490117e-10 BR00117005 PTK2B shuffled crispr N15 A549 144 2494 Large -0.08300326609029779 7.861981993833436e-10 BR00117004 S100B shuffled crispr D22 A549 144 3123 Large -0.15885793824774164 8.950934702303502e-10 BR00117001 OPRL1 shuffled crispr A11 A549 144 841 Large -0.35190763052208834 1.1741570551462296e-09 BR00117000 RPL23A shuffled crispr M18 A549 144 166 Large -0.09389965768399054 3.427544823881587e-09 BR00117005 PDPK1 shuffled crispr N18 A549 144 2282 Large -0.0786022482061929 3.956149179692827e-09 BR00117004 AKT1 shuffled crispr J19 A549 144 3225 Large -0.0819913023492015 4.121423316214594e-09 BR00117004 PORCN shuffled crispr L13 A549 144 2968 Large -0.28238527933890084 6.455172301701803e-09 BR00117005 ATP5F1D shuffled crispr E15 A549 144 237 Large -0.11670536113655243 4.354885392709841e-15 BR00117005 LPAR1 shuffled crispr L01 A549 144 2470 Metaphase -0.10085285735569044 1.0312991445752033e-14 BR00117004 AKT1 shuffled crispr J19 A549 144 3225 Metaphase -0.09572488223039993 2.1009373958781653e-10 BR00117005 PTK2B shuffled crispr N15 A549 144 2494 Metaphase -0.09926609738014133 1.0392029108655316e-09 BR00117005 PLA2G1B shuffled crispr J11 A549 144 2152 Metaphase -0.10858444980388454 2.119720950651774e-09 BR00117001 LPAR1 shuffled crispr L01 A549 144 1739 Metaphase -0.09405240864252407 2.7967591266564704e-09 BR00117001 CACNA2D3 shuffled crispr O07 A549 144 2289 Metaphase -0.08133061160807156 3.3840458423936677e-09 BR00117003 TUBB4B shuffled crispr J13 A549 144 3036 Metaphase -0.09308529825203184 4.1586079183830874e-08 BR00117003 CDK2 shuffled crispr L19 A549 144 2027 Metaphase -0.0887238805781797 2.6857865675712155e-07 BR00117004 MET shuffled crispr H13 A549 144 1991 Metaphase -0.09184926282352696 6.99164490219359e-07 BR00117004 SCNN1G shuffled crispr P15 A549 144 1752 Metaphase -0.0812595244379796 4.891804226636913e-07 BR00117001 CACNA2D3 shuffled crispr O07 A549 144 2289 MetaphaseAlignment -0.09309888827195908 5.050953950186775e-07 BR00117001 LPAR1 shuffled crispr L01 A549 144 1739 MetaphaseAlignment -0.12863214133932366 5.144391062547444e-07 BR00117001 PTPN2 shuffled crispr A15 A549 144 905 MetaphaseAlignment -0.11295190087912259 4.170168196742482e-06 BR00117001 DDR2 shuffled crispr A03 A549 144 1016 MetaphaseAlignment -0.09408736744395375 4.5553689527571954e-06 BR00117001 FOXM1 shuffled crispr F23 A549 144 1460 MetaphaseAlignment -0.16338226990400903 7.0589498448115425e-06 BR00117005 CDK7 shuffled crispr E12 A549 144 460 MetaphaseAlignment -0.1318624641833811 8.705360099688341e-06 BR00117001 PPAT shuffled crispr E13 A549 144 698 MetaphaseAlignment -0.13332116899309673 1.025467857553631e-05 BR00117001 SIRT2 shuffled crispr P01 A549 144 679 MetaphaseAlignment -0.13105413105413105 1.1308819797525524e-05 BR00117001 COMT shuffled crispr A12 A549 144 702 MetaphaseAlignment -0.09157077668233041 1.717582861261984e-05 BR00117000 S1PR1 shuffled crispr P23 A549 144 1373 MetaphaseAlignment -0.14788862546429268 5.4353495033427425e-24 BR00117005 LPAR1 shuffled crispr L01 A549 144 2470 OutOfFocus -0.15090480494446165 3.016724023850377e-23 BR00117001 CACNA2D3 shuffled crispr O07 A549 144 2289 OutOfFocus -0.16342349384585014 9.42649905732557e-21 BR00117001 LPAR1 shuffled crispr L01 A549 144 1739 OutOfFocus -0.1574892699187346 2.166212378939488e-18 BR00117001 HPGDS shuffled crispr P14 A549 144 1659 OutOfFocus -0.11208148906414453 4.0909319917084195e-18 BR00117004 AKT1 shuffled crispr J19 A549 144 3225 OutOfFocus -0.167427701674277 1.717000129759932e-16 BR00117001 GJB4 shuffled crispr N01 A549 144 1314 OutOfFocus -0.10988296716773538 2.367202564963166e-16 BR00117004 AKR1B1 shuffled crispr L21 A549 144 3024 OutOfFocus -0.13727791163266367 1.0309636564214623e-15 BR00117001 SLC29A1 shuffled crispr N21 A549 144 1860 OutOfFocus -0.13032452150154777 2.4438301943878194e-13 BR00117001 CACNG1 shuffled crispr N23 A549 144 1738 OutOfFocus -0.10625082695458261 1.0059834047460878e-12 BR00117005 PTK2B shuffled crispr N15 A549 144 2494 OutOfFocus -0.08698711621891488 5.5359727140607274e-08 BR00117005 PDPK1 shuffled crispr N18 A549 144 2282 Polylobed -0.11188922556849189 5.715651056521833e-08 BR00117000 S1PR1 shuffled crispr P23 A549 144 1373 Polylobed -0.15138002415042262 2.6662232580603095e-07 BR00117002 PRKCB shuffled crispr M03 A549 144 680 Polylobed -0.08235798898716921 3.2327408376688303e-07 BR00117001 CACNA2D3 shuffled crispr O07 A549 144 2289 Polylobed -0.08670932991157436 2.0524565336139994e-06 BR00117000 SCNN1G shuffled crispr P15 A549 144 1821 Polylobed -0.17667483328736228 2.4064176917328028e-06 BR00117002 OPRM1 shuffled crispr P22 A549 144 431 Polylobed -0.16604077253218885 4.177478944898025e-06 BR00117005 MAPK14 shuffled crispr M17 A549 144 464 Polylobed -0.08325933771599751 1.0834967696771132e-05 BR00117003 CDK4 shuffled crispr B15 A549 144 1738 Polylobed -0.0818283023044668 1.3645207173309638e-05 BR00117004 GJB4 shuffled crispr N01 A549 144 1766 Polylobed -0.10176131323907507 1.9072043124813182e-05 BR00117000 RPL3 shuffled crispr H11 A549 144 1107 Polylobed -0.25281440357776236 1.2785728074575119e-11 BR00117000 AURKB shuffled crispr C13 A549 144 396 Prometaphase -0.41926536731634184 1.5257011950173678e-09 BR00117002 AURKB shuffled crispr C13 A549 144 115 Prometaphase -0.2504958029702057 1.1869128834343454e-08 BR00117000 PLK1 shuffled crispr G09 A549 144 293 Prometaphase -0.26277421684571634 6.903381568668759e-07 BR00117003 AURKB shuffled crispr C13 A549 144 212 Prometaphase -0.20380276334136138 9.063830978158109e-07 BR00117001 PLK1 shuffled crispr G09 A549 144 345 Prometaphase -0.14524119046899225 9.544388604314026e-07 BR00117001 AURKB shuffled crispr C13 A549 144 682 Prometaphase -0.49907510173880876 2.14533566376596e-06 BR00117002 RPL23A shuffled crispr M18 A549 144 51 Prometaphase -0.11485793170051656 2.8858254292239587e-06 BR00117004 BAX shuffled crispr E06 A549 144 1013 Prometaphase -0.278018018018018 1.2961405702852455e-05 BR00117005 AURKB shuffled crispr C13 A549 144 150 Prometaphase -0.10590722664679245 1.581638032309183e-05 BR00117001 HDAC6 shuffled crispr L10 A549 144 1039 Prometaphase -0.4782882882882883 4.0180488433018456e-16 BR00117005 AURKB shuffled crispr C13 A549 144 150 SmallIrregular -0.2813054206183977 2.8024830689154382e-14 BR00117000 AURKB shuffled crispr C13 A549 144 396 SmallIrregular -0.3784192470885619 5.082696298231281e-14 BR00117003 AURKB shuffled crispr C13 A549 144 212 SmallIrregular -0.1959756239769542 6.6575191751160836e-12 BR00117001 AURKB shuffled crispr C13 A549 144 682 SmallIrregular -0.10253663140199594 9.693879389661862e-12 BR00117005 LPAR1 shuffled crispr L01 A549 144 2470 SmallIrregular -0.3714689265536723 1.823638239155501e-11 BR00117004 AURKB shuffled crispr C13 A549 144 176 SmallIrregular -0.10491887797741413 2.1749152826051764e-11 BR00117005 PDPK1 shuffled crispr N18 A549 144 2282 SmallIrregular -0.11462153398555659 2.1341941474542858e-10 BR00117003 CDK4 shuffled crispr B15 A549 144 1738 SmallIrregular -0.10109876974035564 1.6281188113864366e-09 BR00117003 LYN shuffled crispr N13 A549 144 2038 SmallIrregular -0.10244161358811041 5.031553198705693e-09 BR00117003 BTK shuffled crispr P17 A549 144 1884 SmallIrregular -0.17661890327914026 1.050316383476017e-05 BR00118048 RPL3 shuffled crispr K04 U2OS 96 382 ADCCM -0.11812216831475378 2.2776428489327008e-05 BR00118045 KCNN1 shuffled crispr D01 U2OS 96 804 ADCCM -0.12010443864229765 3.117422231709646e-05 BR00118045 PDE7A shuffled crispr C22 U2OS 96 766 ADCCM -0.1202377170195668 4.4462306046365715e-05 BR00118045 S100B shuffled crispr D22 U2OS 96 733 ADCCM -0.115 4.9992211989365256e-05 BR00118045 CA14 shuffled crispr C19 U2OS 96 800 ADCCM -0.16235189728065139 5.2170507109713376e-05 BR00118045 KRAS shuffled crispr F07 U2OS 96 391 ADCCM -0.12514028131078858 6.201400552578901e-05 BR00118045 TGFBR1 shuffled crispr P24 U2OS 96 656 ADCCM -0.1239075187503874 6.932343758042666e-05 BR00118045 CASP3 shuffled crispr D19 U2OS 96 663 ADCCM -0.11608906588283632 0.0001147873158890732 BR00118045 AKR1C1 shuffled crispr B06 U2OS 96 712 ADCCM -0.11849632437867733 0.00015483130901252571 BR00118048 CCR1 shuffled crispr G02 U2OS 96 666 ADCCM -0.19673348181143283 4.175465512848618e-08 BR00118047 AVPR1A shuffled crispr J07 U2OS 96 447 Anaphase -0.15687388410972244 5.171964450486926e-07 BR00118047 BRD4 shuffled crispr J16 U2OS 96 606 Anaphase -0.14735533677110213 5.725849763598197e-07 BR00118047 DHH shuffled crispr K21 U2OS 96 682 Anaphase -0.14437712310534576 6.691132870813083e-07 BR00118047 ATP5F1D shuffled crispr G21 U2OS 96 710 Anaphase -0.1440677966101695 7.968922755800356e-07 BR00118047 ERBB2 shuffled crispr H12 U2OS 96 708 Anaphase -0.14484692084572495 4.176069391643651e-06 BR00118047 USP1 shuffled crispr K18 U2OS 96 618 Anaphase -0.15985560194850382 7.117456233913898e-06 BR00118047 CDK9 shuffled crispr I20 U2OS 96 480 Anaphase -0.11881506139313507 8.091958108709779e-06 BR00118047 F10 shuffled crispr H07 U2OS 96 867 Anaphase -0.16787252368647718 8.268466967121092e-06 BR00118047 RPL3 shuffled crispr K04 U2OS 96 432 Anaphase -0.13971088857784883 1.8711756634026877e-05 BR00118047 NAMPT shuffled crispr I09 U2OS 96 587 Anaphase -0.09273978597286868 2.0051961488111864e-05 BR00118047 RGS4 shuffled crispr N11 U2OS 96 1323 Apoptosis -0.12083848355034796 2.312572842177204e-05 BR00118045 KCNJ1 shuffled crispr F03 U2OS 96 770 Apoptosis -0.10487979249916246 6.459882542677536e-05 BR00118047 EDNRB shuffled crispr K06 U2OS 96 931 Apoptosis -0.0900077106934439 0.0002664290939756236 BR00118047 GPR119 shuffled crispr P21 U2OS 96 1094 Apoptosis -0.12201582049887187 0.00031987004565980974 BR00118046 S1PR1 shuffled crispr P23 U2OS 96 579 Apoptosis -0.19122257053291536 0.0003713554498890932 BR00118048 RPL23A shuffled crispr M18 U2OS 96 231 Apoptosis -0.09049827494493497 0.0005002462005861313 BR00118048 LPAR1 shuffled crispr L01 U2OS 96 999 Apoptosis -0.10320388685247943 0.0005486559771392532 BR00118046 KCNJ1 shuffled crispr E14 U2OS 96 760 Apoptosis -0.10145295746435726 0.0009299765114096814 BR00118046 ADH1C shuffled crispr P04 U2OS 96 736 Apoptosis -0.09222146546342017 0.0014833606508599833 BR00118046 CHRM2 shuffled crispr O22 U2OS 96 839 Apoptosis -0.11496001629984577 3.3434850909808596e-05 BR00118045 CYP2A6 shuffled crispr O04 U2OS 96 821 Binuclear -0.12204056496950674 4.267798349560086e-05 BR00118047 ATP5F1D shuffled crispr G21 U2OS 96 710 Binuclear -0.11639357743467445 5.621738242795022e-05 BR00118048 CACNB4 shuffled crispr I23 U2OS 96 766 Binuclear -0.12951887648849256 6.016798996482108e-05 BR00118047 PAK1 shuffled crispr K10 U2OS 96 610 Binuclear -0.1034552302157936 8.929475505233697e-05 BR00118048 HBB shuffled crispr M08 U2OS 96 923 Binuclear -0.11294338736199201 9.340571679396924e-05 BR00118046 SLC7A11 shuffled crispr A05 U2OS 96 774 Binuclear -0.11086738225458942 0.00011479141905674246 BR00118045 BRD4 shuffled crispr M19 U2OS 96 786 Binuclear -0.09795214805234845 0.00012264795402518365 BR00118045 EDNRB shuffled crispr K06 U2OS 96 998 Binuclear -0.10794872727052393 0.00012921313093157102 BR00118045 HDAC6 shuffled crispr K12 U2OS 96 812 Binuclear -0.10616017651619059 0.000176432555704894 BR00118048 BRD4 shuffled crispr M19 U2OS 96 820 Binuclear -0.10499170790483431 4.916980379963183e-05 BR00118048 EDNRB shuffled crispr J03 U2OS 96 948 Elongated -0.146862704493684 0.00012579949666068437 BR00118048 AKR1C1 shuffled crispr B13 U2OS 96 439 Elongated -0.11118097588685824 0.0002675145001190322 BR00118048 KRAS shuffled crispr F07 U2OS 96 715 Elongated -0.09386055327958351 0.00040181508178664405 BR00118045 PTGIS shuffled crispr I16 U2OS 96 956 Elongated -0.10453458330763485 0.0004234296553474134 BR00118048 CACNB4 shuffled crispr I23 U2OS 96 766 Elongated -0.25862068965517243 0.0005595998053559201 BR00118047 PLK1 shuffled crispr F13 U2OS 96 116 Elongated -0.08435178856231487 0.0010627509738730897 BR00118045 OPRM1 shuffled crispr C23 U2OS 96 1050 Elongated -0.12581787567374653 0.0010678731957805897 BR00118047 SLC7A11 shuffled crispr P05 U2OS 96 469 Elongated -0.08298231942967262 0.0011476756792608955 BR00118045 HSD11B1 shuffled crispr O23 U2OS 96 1067 Elongated -0.10107017610925896 0.001343621785967419 BR00118047 SIRT2 shuffled crispr P01 U2OS 96 703 Elongated -0.1176029349862248 9.518216223556538e-05 BR00118045 SIRT2 shuffled crispr P01 U2OS 96 709 Grape -0.15030146425495264 0.00010339874203888086 BR00118047 RPL3 shuffled crispr K04 U2OS 96 432 Grape -0.09669546140134376 0.0002925645405689688 BR00118045 GPR55 shuffled crispr C21 U2OS 96 935 Grape -0.10065359477124183 0.0008542980869237831 BR00118045 ATM shuffled crispr F14 U2OS 96 765 Grape -0.09650638794842455 0.0008546193483140453 BR00118045 ADH1C shuffled crispr D02 U2OS 96 824 Grape -0.10390211014869292 0.0009765101689878594 BR00118045 BTK shuffled crispr P17 U2OS 96 697 Grape -0.09842480100544616 0.0010155599193087887 BR00118046 IMPDH1 shuffled crispr F15 U2OS 96 775 Grape -0.1017729216000383 0.0011686564903929555 BR00118045 IL1B shuffled crispr H06 U2OS 96 709 Grape -0.08620022216985895 0.0013010261090203546 BR00118045 DNMT3A shuffled crispr L04 U2OS 96 976 Grape -0.16005274072556902 0.0013082042647193598 BR00118046 RPL23A shuffled crispr G14 U2OS 96 278 Grape -0.12924281984334204 5.398798109548276e-06 BR00118046 P3H1 shuffled crispr I01 U2OS 96 766 Hole -0.12289029535864979 3.912696325689296e-05 BR00118045 AKR1C1 shuffled crispr B06 U2OS 96 712 Hole -0.12414547443259502 3.9864534117579304e-05 BR00118046 SIRT2 shuffled crispr P01 U2OS 96 689 Hole -0.19184541880256806 5.141274678213057e-05 BR00118045 KCNN1 shuffled crispr B24 U2OS 96 284 Hole -0.15986612036118794 7.047163027367204e-05 BR00118045 KRAS shuffled crispr F07 U2OS 96 391 Hole -0.13390390826975468 7.704488168837437e-05 BR00118046 GRIN2A shuffled crispr A23 U2OS 96 563 Hole -0.15728349484694662 9.278530361507914e-05 BR00118047 MAPK8 shuffled crispr D13 U2OS 96 394 Hole -0.11397215060770037 9.536886226919065e-05 BR00118046 KCNN4 shuffled crispr K01 U2OS 96 751 Hole -0.12048192771084337 0.00012824670595432954 BR00118047 GJB4 shuffled crispr H01 U2OS 96 664 Hole -0.2710185420370841 0.0001421588372966244 BR00118047 PLD1 shuffled crispr F11 U2OS 96 127 Hole -0.17907961813944084 1.3015956465148025e-06 BR00118046 AURKB shuffled crispr C13 U2OS 96 434 Interphase -0.10626398210290827 8.146472577148644e-05 BR00118045 MAPK8 shuffled crispr D07 U2OS 96 894 Interphase -0.11357702349869452 0.0001007448564741844 BR00118046 P3H1 shuffled crispr I01 U2OS 96 766 Interphase -0.12048192771084337 0.00012824670595432954 BR00118047 GJB4 shuffled crispr H01 U2OS 96 664 Interphase -0.10999721526037315 0.00018477222982124495 BR00118047 OPRM1 shuffled crispr C23 U2OS 96 756 Interphase -0.12678571428571428 0.0002424260326758614 BR00118047 AURKB shuffled crispr C13 U2OS 96 560 Interphase -0.10076752128631078 0.00026042444475534934 BR00118047 CHEK2 shuffled crispr K03 U2OS 96 868 Interphase -0.10942765192149934 0.00047411957773695767 BR00118046 SIRT2 shuffled crispr P01 U2OS 96 689 Interphase -0.08976090253021307 0.0005316896578659191 BR00118048 P2RY12 shuffled crispr O21 U2OS 96 1013 Interphase -0.13047792217381673 0.0006268555677260903 BR00118047 CDC25A shuffled crispr D06 U2OS 96 467 Interphase -0.08449297847794088 0.00014109832558937662 BR00118047 RGS4 shuffled crispr N11 U2OS 96 1323 Large -0.1624150497389934 0.0008815909154131828 BR00118048 SLCO2B1 shuffled crispr A21 U2OS 96 284 Large -0.08183133222733564 0.0009140532400465991 BR00118045 PDE3A shuffled crispr O08 U2OS 96 1131 Large -0.09849323802812175 0.0010094136255276898 BR00118046 SLC7A11 shuffled crispr A05 U2OS 96 774 Large -0.09002085783811842 0.001083324738090743 BR00118045 LYN shuffled crispr F22 U2OS 96 916 Large -0.08289122459351764 0.001084495224803048 BR00118045 GLRA3 shuffled crispr E21 U2OS 96 1079 Large -0.09146720994215057 0.0012094235485908174 BR00118048 HTR3A shuffled crispr O02 U2OS 96 877 Large -0.08130559197989808 0.0018876527444552057 BR00118045 EZH2 shuffled crispr C05 U2OS 96 1043 Large -0.1212950053745703 0.0028974840624097233 BR00118046 AURKB shuffled crispr C13 U2OS 96 434 Large -0.10395820559660689 0.004162537301742944 BR00118046 GRIN2A shuffled crispr A23 U2OS 96 563 Large -0.1982142857142857 4.907953158938926e-10 BR00118047 AURKB shuffled crispr C13 U2OS 96 560 Metaphase -0.2022913762092783 2.5682873071327855e-08 BR00118046 AURKB shuffled crispr C13 U2OS 96 434 Metaphase -0.3390520955738347 2.7098413434835186e-06 BR00118048 PLK1 shuffled crispr F13 U2OS 96 111 Metaphase -0.1396006833226564 3.5416868694110677e-06 BR00118046 CA5A shuffled crispr M01 U2OS 96 672 Metaphase -0.14987559416050583 3.7525263460094674e-06 BR00118046 S1PR1 shuffled crispr P23 U2OS 96 579 Metaphase -0.1455014323234609 8.01724497591797e-06 BR00118046 PPAT shuffled crispr E13 U2OS 96 578 Metaphase -0.12239221140472879 4.120805105264472e-05 BR00118046 TGFBR1 shuffled crispr P24 U2OS 96 719 Metaphase -0.1269072408602953 6.303139143858786e-05 BR00118047 MMP2 shuffled crispr D14 U2OS 96 635 Metaphase -0.15023132848645077 7.529831757031824e-05 BR00118046 KCNMA1 shuffled crispr A07 U2OS 96 445 Metaphase -0.12357595303835356 7.752484505022648e-05 BR00118047 S1PR1 shuffled crispr P23 U2OS 96 658 Metaphase -0.13543284846773054 3.9355081418084946e-05 BR00118047 PDE7A shuffled crispr C10 U2OS 96 584 MetaphaseAlignment -0.11711217464684208 0.0001083181244433512 BR00118045 IL1B shuffled crispr H06 U2OS 96 709 MetaphaseAlignment -0.16487455197132617 0.0009957052979697517 BR00118045 PLK1 shuffled crispr G09 U2OS 96 279 MetaphaseAlignment -0.08851439871462119 0.0015302835992772594 BR00118045 TNNC1 shuffled crispr D09 U2OS 96 899 MetaphaseAlignment -0.09523809523809523 0.0016490569350625357 BR00118046 SLC7A11 shuffled crispr A05 U2OS 96 774 MetaphaseAlignment -0.10101287285545367 0.0018619748773709502 BR00118047 PDE4D shuffled crispr J24 U2OS 96 670 MetaphaseAlignment -0.09752747252747253 0.0019546461684521056 BR00118047 ALK shuffled crispr G06 U2OS 96 728 MetaphaseAlignment -0.1437308868501529 0.0022991139830571233 BR00118047 TUBB shuffled crispr J17 U2OS 96 327 MetaphaseAlignment -0.13010204081632654 0.0025996592153397216 BR00118045 RPL3 shuffled crispr K04 U2OS 96 392 MetaphaseAlignment -0.08797263838180368 0.002722860148350922 BR00118045 PTGIR shuffled crispr G10 U2OS 96 846 MetaphaseAlignment -0.10540540540540541 8.66135861757296e-06 BR00118047 KCNQ2 shuffled crispr P13 U2OS 96 1110 OutOfFocus -0.1641798697636261 4.072211538229851e-05 BR00118047 MAPK8 shuffled crispr D13 U2OS 96 394 OutOfFocus -0.09744911527737589 5.4008244599473605e-05 BR00118047 GPR119 shuffled crispr P21 U2OS 96 1094 OutOfFocus -0.13392857142857142 8.501379323238266e-05 BR00118047 AURKB shuffled crispr C13 U2OS 96 560 OutOfFocus -0.13677366040361866 0.0002083411865734464 BR00118047 CDK9 shuffled crispr I20 U2OS 96 480 OutOfFocus -0.1317978533094812 0.00021439224554750346 BR00118047 ADRA2B shuffled crispr H22 U2OS 96 520 OutOfFocus -0.11525170728066575 0.0003853623381626912 BR00118047 MMP2 shuffled crispr D14 U2OS 96 635 OutOfFocus -0.12625250501002003 0.0006933342437268784 BR00118047 RPL3 shuffled crispr H11 U2OS 96 499 OutOfFocus -0.1296267114081517 0.0007117836068052214 BR00118048 AURKB shuffled crispr C13 U2OS 96 466 OutOfFocus -0.13065697954358013 0.0007148339228962453 BR00118047 PNLIP shuffled crispr C06 U2OS 96 457 OutOfFocus -0.15019128134888773 3.39875424477806e-07 BR00118047 DHH shuffled crispr K21 U2OS 96 682 Polylobed -0.15408880290912957 3.662835049727835e-06 BR00118047 PTGIS shuffled crispr I16 U2OS 96 546 Polylobed -0.16513976063311372 7.3978651514895e-06 BR00118047 CACNA2D3 shuffled crispr N24 U2OS 96 452 Polylobed -0.1440799020497007 7.446444214661307e-06 BR00118046 OPRL1 shuffled crispr A11 U2OS 96 596 Polylobed -0.13675368339339009 1.720334018208155e-05 BR00118047 USP1 shuffled crispr K18 U2OS 96 618 Polylobed -0.1827133672460082 2.1737581009096664e-05 BR00118048 PLA2G1B shuffled crispr J11 U2OS 96 336 Polylobed -0.13523778607368933 2.5354650493242237e-05 BR00118047 BRD4 shuffled crispr J16 U2OS 96 606 Polylobed -0.15055943271710906 3.0836451745767e-05 BR00118047 USP1 shuffled crispr N12 U2OS 96 481 Polylobed -0.10954767105351713 3.4228874165542875e-05 BR00118046 ICAM1 shuffled crispr C20 U2OS 96 903 Polylobed -0.12524137060642393 3.733323108019349e-05 BR00118046 SIRT2 shuffled crispr P01 U2OS 96 689 Polylobed -0.12476619781535239 6.596811934740989e-05 BR00118045 TGFBR1 shuffled crispr P24 U2OS 96 656 Prometaphase -0.15935069680045932 8.6650529992648e-05 BR00118045 KRAS shuffled crispr F07 U2OS 96 391 Prometaphase -0.10997552093747538 0.0001013806919075373 BR00118045 HDAC6 shuffled crispr K12 U2OS 96 812 Prometaphase -0.09440185599081378 0.00021969310853683346 BR00118048 P2RY12 shuffled crispr O21 U2OS 96 1013 Prometaphase -0.1328849915182751 0.00047292988938963846 BR00118048 AURKB shuffled crispr C13 U2OS 96 466 Prometaphase -0.21454844006568144 0.0005439279032080046 BR00118046 PLK1 shuffled crispr G09 U2OS 96 175 Prometaphase -0.0958112023177209 0.0016670302756236718 BR00118045 CLK1 shuffled crispr N05 U2OS 96 760 Prometaphase -0.12428028650184651 0.0020948638144250562 BR00118046 AURKB shuffled crispr C13 U2OS 96 434 Prometaphase -0.09399477806788512 0.0022880796955403867 BR00118045 PDE7A shuffled crispr C22 U2OS 96 766 Prometaphase -0.08061184711967558 0.002508013935906563 BR00118048 IGF1R shuffled crispr M22 U2OS 96 1017 Prometaphase -0.23193133321271592 9.200334484886519e-11 BR00118046 AURKB shuffled crispr C13 U2OS 96 434 SmallIrregular -0.18928571428571428 3.486138209414909e-09 BR00118047 AURKB shuffled crispr C13 U2OS 96 560 SmallIrregular -0.1869919076001817 1.3265282638292297e-07 BR00118048 AURKB shuffled crispr C13 U2OS 96 466 SmallIrregular -0.11981981981981982 2.3258431850380218e-07 BR00118047 KCNQ2 shuffled crispr P13 U2OS 96 1110 SmallIrregular -0.23928034280200913 3.5531201087671696e-07 BR00118047 RPL23A shuffled crispr M18 U2OS 96 262 SmallIrregular -0.12170726185887434 2.637335126638719e-06 BR00118046 ICAM1 shuffled crispr C20 U2OS 96 903 SmallIrregular -0.15363287359590502 4.457622368781604e-06 BR00118046 CDK2 shuffled crispr F08 U2OS 96 546 SmallIrregular -0.1638655462184874 5.38124765004836e-06 BR00118047 ATM shuffled crispr G12 U2OS 96 476 SmallIrregular -0.14298947171564574 1.0813556309544734e-05 BR00118047 NAMPT shuffled crispr I09 U2OS 96 587 SmallIrregular -0.13846237082724666 1.4730228285513163e-05 BR00118047 BRD4 shuffled crispr J16 U2OS 96 606 SmallIrregular -0.16849462019545372 1.95215349211455e-24 BR00116999 CACNA2D3 shuffled crispr N24 U2OS 144 1932 ADCCM -0.15611434473709923 9.492621666806405e-22 BR00116996 OPRM1 shuffled crispr P22 U2OS 144 2002 ADCCM -0.137221269296741 1.4949729412734152e-19 BR00116996 ABL1 shuffled crispr P20 U2OS 144 2332 ADCCM -0.17418351477449456 1.8882630012565577e-17 BR00116996 TGFBR1 shuffled crispr P24 U2OS 144 1286 ADCCM -0.22195169347187454 3.5860983613713215e-16 BR00116998 FFAR2 shuffled crispr A24 U2OS 144 726 ADCCM -0.13290367225343358 5.151040565985092e-16 BR00116996 KCNK1 shuffled crispr N20 U2OS 144 2022 ADCCM -0.15078328981723238 1.3221791848670527e-15 BR00116996 S1PR1 shuffled crispr P23 U2OS 144 1532 ADCCM -0.13426966292134832 2.1188186157063406e-14 BR00116996 CHRM2 shuffled crispr O22 U2OS 144 1780 ADCCM -0.12331497793051141 7.125635227978442e-14 BR00116996 CACNG1 shuffled crispr N23 U2OS 144 2022 ADCCM -0.13581887852627647 1.0377350644950704e-13 BR00116996 GRIN2A shuffled crispr A23 U2OS 144 1642 ADCCM -0.2214120565121743 1.3020296520607069e-12 BR00116999 SLC7A11 shuffled crispr P05 U2OS 144 566 Anaphase -0.11228855095801914 6.517926973566092e-10 BR00116996 PDE7A shuffled crispr C10 U2OS 144 1718 Anaphase -0.12947882736156352 2.1810758594276306e-09 BR00116997 PDPK1 shuffled crispr E16 U2OS 144 1228 Anaphase -0.22436135273666707 5.600917480494453e-09 BR00116999 RPL3 shuffled crispr K04 U2OS 144 382 Anaphase -0.12418300653594772 1.2176983770859574e-08 BR00116996 MAPK8 shuffled crispr D13 U2OS 144 1224 Anaphase -0.09296524371151237 1.6906989576475308e-08 BR00116999 NAMPT shuffled crispr I09 U2OS 144 2144 Anaphase -0.1221529879532372 1.8080977677754082e-08 BR00116996 ERBB2 shuffled crispr I11 U2OS 144 1230 Anaphase -0.1076503503079889 3.26637208141545e-08 BR00116998 CDK7 shuffled crispr E12 U2OS 144 1530 Anaphase -0.09319526627218935 4.3872269510599574e-08 BR00116998 KCTD16 shuffled crispr D08 U2OS 144 2028 Anaphase -0.08871701546860783 6.020647686262739e-08 BR00116999 PPAT shuffled crispr G13 U2OS 144 2198 Anaphase -0.31383945333032964 1.3914544059492949e-84 BR00116999 CACNA2D3 shuffled crispr N24 U2OS 144 1932 Apoptosis -0.2607204116638079 4.686652071266627e-70 BR00116996 ABL1 shuffled crispr P20 U2OS 144 2332 Apoptosis -0.26711711442250363 2.167084657079359e-63 BR00116996 OPRM1 shuffled crispr P22 U2OS 144 2002 Apoptosis -0.32581648522550544 8.720324799818073e-61 BR00116996 TGFBR1 shuffled crispr P24 U2OS 144 1286 Apoptosis -0.2839425587467363 8.556370503512967e-55 BR00116996 S1PR1 shuffled crispr P23 U2OS 144 1532 Apoptosis -0.264385550565278 1.6263413083711155e-54 BR00116996 PDE3A shuffled crispr P18 U2OS 144 1760 Apoptosis -0.28371161548731644 1.6864584779292614e-53 BR00116996 P2RY12 shuffled crispr P19 U2OS 144 1498 Apoptosis -0.24831460674157305 1.4011555705637036e-48 BR00116996 CHRM2 shuffled crispr O22 U2OS 144 1780 Apoptosis -0.25373335585645657 6.884537881860549e-47 BR00116996 GRIN2A shuffled crispr A23 U2OS 144 1642 Apoptosis -0.2259257840788814 6.07395085242875e-42 BR00116996 HTR3A shuffled crispr O20 U2OS 144 1856 Apoptosis -0.2688464797948916 5.59222257580711e-62 BR00116999 CACNA2D3 shuffled crispr N24 U2OS 144 1932 Binuclear -0.2629875114905055 2.4228124886959094e-61 BR00116996 OPRM1 shuffled crispr P22 U2OS 144 2002 Binuclear -0.26179775280898876 5.140909259868018e-54 BR00116996 CHRM2 shuffled crispr O22 U2OS 144 1780 Binuclear -0.22041166380789023 5.053548114822474e-50 BR00116996 ABL1 shuffled crispr P20 U2OS 144 2332 Binuclear -0.18342303615941644 4.122909425852438e-44 BR00116996 IGF1R shuffled crispr M22 U2OS 144 2964 Binuclear -0.2698289269051322 1.398881903451612e-41 BR00116996 TGFBR1 shuffled crispr P24 U2OS 144 1286 Binuclear -0.2447780678851175 1.1011149179085723e-40 BR00116996 S1PR1 shuffled crispr P23 U2OS 144 1532 Binuclear -0.2205384333277626 5.69496782867747e-40 BR00116996 HTR3A shuffled crispr O20 U2OS 144 1856 Binuclear -0.23379052369077308 7.644369229612581e-39 BR00116996 SLCO2B1 shuffled crispr A21 U2OS 144 1604 Binuclear -0.22120889473955913 3.698775923181601e-38 BR00116996 PDE3A shuffled crispr P18 U2OS 144 1760 Binuclear -0.10799836943112455 2.8865404802891445e-10 BR00116999 CACNA2D3 shuffled crispr N24 U2OS 144 1932 Elongated -0.08627946127946128 4.088850043647908e-08 BR00116996 CATSPER4 shuffled crispr P02 U2OS 144 2376 Elongated -0.08157228302826099 4.482724466605623e-08 BR00116997 CACNA2D3 shuffled crispr N24 U2OS 144 2630 Elongated -0.10239162929745889 1.5867032499086826e-06 BR00116996 SIRT2 shuffled crispr O19 U2OS 144 1338 Elongated -0.08270521893276385 2.0856003306088923e-06 BR00116996 OPRM1 shuffled crispr P22 U2OS 144 2002 Elongated -0.06768657800684375 2.2804750100793354e-06 BR00116996 IGF1R shuffled crispr M22 U2OS 144 2964 Elongated -0.0723183273944589 3.0675479791386605e-06 BR00116999 CACNG1 shuffled crispr N23 U2OS 144 2538 Elongated -0.08292752049255692 3.2711360281528324e-06 BR00116999 PAK4 shuffled crispr G22 U2OS 144 1922 Elongated -0.10432031540783833 3.372311602617338e-06 BR00116999 CDK9 shuffled crispr I20 U2OS 144 1204 Elongated -0.0926892950391645 3.7892941370143247e-06 BR00116996 S1PR1 shuffled crispr P23 U2OS 144 1532 Elongated -0.13137222308090868 1.0240186091631086e-15 BR00116996 BTK shuffled crispr D24 U2OS 144 2028 Grape -0.19805184453017888 4.563496916045411e-14 BR00116996 FFAR2 shuffled crispr A24 U2OS 144 794 Grape -0.1285929998451293 4.0751452795195627e-13 BR00116996 PDE3A shuffled crispr P18 U2OS 144 1760 Grape -0.14930015552099535 6.455519655320399e-13 BR00116996 TGFBR1 shuffled crispr P24 U2OS 144 1286 Grape -0.1097770154373928 1.1860103652439044e-12 BR00116996 ABL1 shuffled crispr P20 U2OS 144 2332 Grape -0.17549094037858082 1.910202346313888e-12 BR00116997 KCNN1 shuffled crispr B24 U2OS 144 890 Grape -0.11925133689839572 5.338206024802145e-12 BR00116999 S1PR1 shuffled crispr P23 U2OS 144 1870 Grape -0.10343550520019698 2.5734780461662028e-11 BR00116996 HPGDS shuffled crispr P14 U2OS 144 2330 Grape -0.11124380257367278 1.7750699940323754e-10 BR00116996 HTR3A shuffled crispr O20 U2OS 144 1856 Grape -0.12140992167101827 2.96942384152821e-10 BR00116996 S1PR1 shuffled crispr P23 U2OS 144 1532 Grape -0.16948471725349903 1.0183297281064114e-21 BR00116996 AURKB shuffled crispr M05 U2OS 144 1692 Hole -0.15444214876033058 1.4819581941663116e-20 BR00116998 P3H1 shuffled crispr I01 U2OS 144 1936 Hole -0.19859448514084926 1.5480758108535605e-20 BR00116998 DNMT3A shuffled crispr L06 U2OS 144 1160 Hole -0.1758957654723127 5.264241662651088e-17 BR00116998 SLCO2B1 shuffled crispr A21 U2OS 144 1228 Hole -0.1692831990978491 1.6255948954555778e-15 BR00116996 KCTD16 shuffled crispr D03 U2OS 144 1204 Hole -0.21640775922179167 2.1592792575554514e-15 BR00116998 FFAR2 shuffled crispr A24 U2OS 144 726 Hole -0.11870506929042285 2.53869269706384e-15 BR00116997 ELANE shuffled crispr H10 U2OS 144 2414 Hole -0.14411862045610227 4.3729661916515454e-15 BR00116996 ADRA2B shuffled crispr H22 U2OS 144 1614 Hole -0.1265197844237804 6.293303751660726e-15 BR00116998 PLD1 shuffled crispr F04 U2OS 144 2070 Hole -0.1380885427573301 6.751512627689233e-15 BR00116998 PDE7A shuffled crispr C10 U2OS 144 1734 Hole -0.22690750247106464 2.374365264601534e-18 BR00116996 FFAR2 shuffled crispr A24 U2OS 144 794 Interphase -0.19470594189695314 2.922616650606895e-15 BR00116997 KCNN1 shuffled crispr B24 U2OS 144 890 Interphase -0.15254567022538554 6.48679611048593e-12 BR00116996 ITGB2 shuffled crispr D23 U2OS 144 1124 Interphase -0.11202567413955747 5.3391817970876604e-11 BR00116998 PARP3 shuffled crispr F12 U2OS 144 1928 Interphase -0.11687752417188232 1.0624363424028577e-10 BR00116996 PDE7A shuffled crispr C10 U2OS 144 1718 Interphase -0.1399662731871838 1.5189558839319394e-10 BR00116996 HSP90AA1 shuffled crispr C03 U2OS 144 1186 Interphase -0.08890104792377872 1.90850367789084e-10 BR00116996 VEGFA shuffled crispr C24 U2OS 144 2900 Interphase -0.11016042780748662 2.6803074578388563e-10 BR00116999 S1PR1 shuffled crispr P23 U2OS 144 1870 Interphase -0.1019067791831054 5.322749569153373e-10 BR00116997 TGFBR1 shuffled crispr P24 U2OS 144 2106 Interphase -0.16664344757128263 7.471353510664408e-10 BR00116996 CCND1 shuffled crispr B23 U2OS 144 776 Interphase -0.21291796736716764 7.001488999836843e-39 BR00116999 CACNA2D3 shuffled crispr N24 U2OS 144 1932 Large -0.1758147512864494 6.899763039296053e-32 BR00116996 ABL1 shuffled crispr P20 U2OS 144 2332 Large -0.1807728199943769 4.048548652806429e-29 BR00116996 OPRM1 shuffled crispr P22 U2OS 144 2002 Large -0.1771519960976155 8.5908977042372e-25 BR00116996 HIF1A shuffled crispr M24 U2OS 144 1772 Large -0.23909512761020882 4.864959134022132e-22 BR00116996 ADA shuffled crispr O24 U2OS 144 862 Large -0.1905132192846034 8.195976673408969e-21 BR00116996 TGFBR1 shuffled crispr P24 U2OS 144 1286 Large -0.15543992442389468 4.2872769431768336e-20 BR00116996 HTR3A shuffled crispr O20 U2OS 144 1856 Large -0.18403293588741204 2.168095578085617e-19 BR00116996 GPR119 shuffled crispr P21 U2OS 144 1280 Large -0.16840731070496084 2.2251346464520474e-19 BR00116996 S1PR1 shuffled crispr P23 U2OS 144 1532 Large -0.15590638067213877 4.025999310928855e-19 BR00116996 PDE3A shuffled crispr P18 U2OS 144 1760 Large -0.23876527484774906 7.531082672009944e-20 BR00116996 CCND1 shuffled crispr B23 U2OS 144 776 Metaphase -0.1350771869639794 5.881494225765451e-19 BR00116996 ABL1 shuffled crispr P20 U2OS 144 2332 Metaphase -0.13527179370527742 1.3169461819711553e-16 BR00116996 BTK shuffled crispr D24 U2OS 144 2028 Metaphase -0.2149411727194465 1.525782728736977e-16 BR00116996 FFAR2 shuffled crispr A24 U2OS 144 794 Metaphase -0.15552099533437014 5.5331880613637075e-14 BR00116996 TGFBR1 shuffled crispr P24 U2OS 144 1286 Metaphase -0.12867237107015642 3.4866108390716557e-13 BR00116996 PDE3A shuffled crispr P18 U2OS 144 1760 Metaphase -0.12071910125802342 3.7134813462271163e-13 BR00116996 OPRM1 shuffled crispr P22 U2OS 144 2002 Metaphase -0.09846439319146912 1.0840491261407062e-12 BR00116996 VEGFA shuffled crispr C24 U2OS 144 2900 Metaphase -0.1014985684407172 2.026326860000237e-12 BR00116997 HRH4 shuffled crispr A08 U2OS 144 2664 Metaphase -0.17248421734203853 1.1303598857510287e-11 BR00116996 ADA shuffled crispr O24 U2OS 144 862 Metaphase -0.2101139601139601 1.5489434654671395e-27 BR00116996 CACNA2D3 shuffled crispr N24 U2OS 144 1404 MetaphaseAlignment -0.1482176380351645 5.192787924629018e-19 BR00116999 CACNA2D3 shuffled crispr N24 U2OS 144 1932 MetaphaseAlignment -0.17573872472783825 9.312925499957397e-18 BR00116996 TGFBR1 shuffled crispr P24 U2OS 144 1286 MetaphaseAlignment -0.1398227520982012 1.464870491383721e-17 BR00116996 OPRM1 shuffled crispr P22 U2OS 144 2002 MetaphaseAlignment -0.15930599369085174 1.86799283053785e-14 BR00116997 S1PR1 shuffled crispr P23 U2OS 144 1268 MetaphaseAlignment -0.13854005785708695 6.000674622601882e-14 BR00116997 HPGDS shuffled crispr P14 U2OS 144 1606 MetaphaseAlignment -0.10106495632367349 1.23119421309256e-13 BR00116996 IGF1R shuffled crispr M22 U2OS 144 2964 MetaphaseAlignment -0.13642297650130547 7.649464803505008e-13 BR00116996 S1PR1 shuffled crispr P23 U2OS 144 1532 MetaphaseAlignment -0.11909547738693467 1.0393297183733037e-12 BR00116999 HPGDS shuffled crispr P14 U2OS 144 1990 MetaphaseAlignment -0.11790248274999479 2.550761747378889e-12 BR00116999 ADA shuffled crispr O06 U2OS 144 1960 MetaphaseAlignment -0.21461897356143078 2.424837220849045e-26 BR00116996 TGFBR1 shuffled crispr P24 U2OS 144 1286 OutOfFocus -0.2606383317922393 3.543751795533448e-24 BR00116996 FFAR2 shuffled crispr A24 U2OS 144 794 OutOfFocus -0.17345451964276495 1.4691373348065765e-23 BR00116996 PDE3A shuffled crispr P18 U2OS 144 1760 OutOfFocus -0.14379667751819225 1.2126123392847725e-20 BR00116996 PDPK1 shuffled crispr N18 U2OS 144 2238 OutOfFocus -0.13936535162950256 3.717840573722391e-20 BR00116996 ABL1 shuffled crispr P20 U2OS 144 2332 OutOfFocus -0.21706251899656975 8.563129656412453e-20 BR00116999 CDK4 shuffled crispr B15 U2OS 144 934 OutOfFocus -0.1440964225395363 1.359100899475934e-18 BR00116996 OPRM1 shuffled crispr P22 U2OS 144 2002 OutOfFocus -0.2043956878226541 1.0317293816291656e-16 BR00116997 KCNN1 shuffled crispr B24 U2OS 144 890 OutOfFocus -0.2182031073783651 1.2406147830345182e-16 BR00116996 CCND1 shuffled crispr B23 U2OS 144 776 OutOfFocus -0.1403737279010802 3.4234367698006097e-16 BR00116996 OPRM1 shuffled crispr C23 U2OS 144 1828 OutOfFocus -0.19635245238223709 4.975139568620214e-15 BR00116996 ADA shuffled crispr O24 U2OS 144 862 Polylobed -0.16950549450549451 1.487089623778743e-13 BR00116996 GAA shuffled crispr L17 U2OS 144 1040 Polylobed -0.14975593088524092 2.4126135327659937e-13 BR00116996 PDPK1 shuffled crispr E16 U2OS 144 1318 Polylobed -0.16176878963615463 3.323055505897372e-13 BR00116996 CSK shuffled crispr B05 U2OS 144 1114 Polylobed -0.10881801125703565 2.0786073152651308e-11 BR00116999 ANXA1 shuffled crispr F24 U2OS 144 2132 Polylobed -0.14297385620915032 2.523217492117532e-11 BR00116996 MAPK8 shuffled crispr D13 U2OS 144 1224 Polylobed -0.13843648208469056 1.1260498270860274e-10 BR00116998 SLCO2B1 shuffled crispr A21 U2OS 144 1228 Polylobed -0.11733090650432017 1.2397059569229416e-10 BR00116996 AURKB shuffled crispr M05 U2OS 144 1692 Polylobed -0.21847958234999643 2.002367659460338e-10 BR00116997 PPAT shuffled crispr E13 U2OS 144 474 Polylobed -0.10027504545242646 2.358373897357889e-10 BR00116999 S100B shuffled crispr D22 U2OS 144 2258 Polylobed -0.10512560900681049 9.798951909576949e-15 BR00116996 IGF1R shuffled crispr M22 U2OS 144 2964 Prometaphase -0.1217874038554372 5.720538666287006e-13 BR00116999 CACNA2D3 shuffled crispr N24 U2OS 144 1932 Prometaphase -0.11659548036793546 2.5395986688434254e-12 BR00116996 OPRM1 shuffled crispr P22 U2OS 144 2002 Prometaphase -0.14000024111782222 1.731339032249506e-11 BR00116999 HTR3A shuffled crispr O20 U2OS 144 1290 Prometaphase -0.1180492173942673 1.788588006451912e-11 BR00116999 LCK shuffled crispr O15 U2OS 144 1812 Prometaphase -0.13034188034188035 8.244800765112315e-11 BR00116996 CACNA2D3 shuffled crispr N24 U2OS 144 1404 Prometaphase -0.2682926829268293 8.648730409818776e-11 BR00116998 CHRM3 shuffled crispr B17 U2OS 144 328 Prometaphase -0.09904074394447714 2.0806867523787476e-10 BR00116996 HPGDS shuffled crispr P14 U2OS 144 2330 Prometaphase -0.12764740862723573 2.5194072176100757e-10 BR00116997 GABRB2 shuffled crispr L22 U2OS 144 1386 Prometaphase -0.11016042780748662 2.6803074578388563e-10 BR00116999 S1PR1 shuffled crispr P23 U2OS 144 1870 Prometaphase -0.15241057542768274 1.9141806825502727e-13 BR00116996 TGFBR1 shuffled crispr P24 U2OS 144 1286 SmallIrregular -0.1182548622062026 3.0374982597958312e-12 BR00116999 CACNA2D3 shuffled crispr N24 U2OS 144 1932 SmallIrregular -0.0946575465377533 5.099653440978181e-12 BR00116996 IGF1R shuffled crispr M22 U2OS 144 2964 SmallIrregular -0.09980747802215954 1.1456500716015825e-11 BR00116999 CYP3A4 shuffled crispr D04 U2OS 144 2580 SmallIrregular -0.0863653483088925 9.783898505265399e-11 BR00116997 CDK2 shuffled crispr F08 U2OS 144 3164 SmallIrregular -0.10514161357941493 1.9724489295153738e-10 BR00116997 KCNH7 shuffled crispr O16 U2OS 144 2072 SmallIrregular -0.12684441441666874 3.6667981952346595e-10 BR00116997 DYRK1B shuffled crispr N16 U2OS 144 1384 SmallIrregular -0.11809045226130653 4.362839932781047e-10 BR00116996 HSD11B1 shuffled crispr O23 U2OS 144 1592 SmallIrregular -0.1114633268279743 4.634797594694543e-10 BR00116997 CSF1R shuffled crispr C08 U2OS 144 1780 SmallIrregular -0.12735501202746125 5.23002247459573e-10 BR00116996 FGF1 shuffled crispr J12 U2OS 144 1352 SmallIrregular -0.09700374531835206 2.7946437911140343e-22 BR00117021 HPGDS shuffled orf O24 A549 48 5340 ADCCM -0.0916585454011117 7.722164365842079e-16 BR00117020 GPR119 shuffled orf N23 A549 48 4215 ADCCM -0.07963899440886588 1.2530654903168006e-14 BR00117021 USP1 shuffled orf G11 A549 48 5130 ADCCM -0.08290472989529003 1.0537251803593761e-12 BR00117021 ASIC1 shuffled orf L21 A549 48 4105 ADCCM -0.06808492178661205 2.6707449292308915e-12 BR00117021 ABL1 shuffled orf C01 A549 48 5870 ADCCM -0.06965644662723007 4.316108375210827e-11 BR00117020 CYP3A4 shuffled orf K09 A549 48 5050 ADCCM -0.0667809013038697 1.6139967597954933e-10 BR00117020 EZH2 shuffled orf D03 A549 48 5195 ADCCM -0.06677305418904105 8.901347084814829e-10 BR00117020 FFAR2 shuffled orf B15 A549 48 4815 ADCCM -0.06559356136820925 1.0199029831261732e-09 BR00117020 HDAC3 shuffled orf N21 A549 48 4970 ADCCM -0.06175236332874938 2.1068617807484934e-09 BR00117021 LCK shuffled orf H01 A549 48 5405 ADCCM -0.11722846441947565 2.2904691470831202e-32 BR00117021 HPGDS shuffled orf O24 A549 48 5340 Anaphase -0.08128779419945333 2.619434537287983e-13 BR00117020 CACNB4 shuffled orf A18 A549 48 4470 Anaphase -0.07979588410175419 7.582038050454067e-12 BR00117021 ASIC1 shuffled orf L21 A549 48 4105 Anaphase -0.07016462537372295 1.293896819801251e-11 BR00117021 PRKCB shuffled orf K14 A549 48 5220 Anaphase -0.07219282331150464 4.170415587886029e-11 BR00117021 ERBB2 shuffled orf I20 A549 48 4705 Anaphase -0.07010831474235156 2.956442938699298e-10 BR00117021 CYP2A6 shuffled orf A15 A549 48 4585 Anaphase -0.0665281423155439 3.2232105523953886e-10 BR00117020 PTK2B shuffled orf J18 A549 48 5080 Anaphase -0.062159958086075 1.6209875957942821e-09 BR00117020 CCND1 shuffled orf B11 A549 48 5395 Anaphase -0.06438631790744467 2.226896415473749e-09 BR00117020 FFAR2 shuffled orf P06 A549 48 4970 Anaphase -0.0634984833164813 4.333990400716817e-09 BR00117020 OPRL1 shuffled orf A23 A549 48 4945 Anaphase -0.14404847265341977 1.5953883612265453e-33 BR00117021 DYRK1B shuffled orf M12 A549 48 3650 Apoptosis -0.12131868131868132 1.4082762617372202e-29 BR00117020 DYRK1B shuffled orf G13 A549 48 4550 Apoptosis -0.10766269365688438 1.7710145613715076e-21 BR00117020 DYRK1B shuffled orf M12 A549 48 4170 Apoptosis -0.08239478769916851 7.7824859563194685e-19 BR00117021 P2RY12 shuffled orf B01 A549 48 6220 Apoptosis -0.09884580078401581 1.7046582055602175e-18 BR00117021 DYRK1B shuffled orf G13 A549 48 4245 Apoptosis -0.08307692307692308 4.989535902929358e-16 BR00117020 MAPK8 shuffled orf I13 A549 48 5200 Apoptosis -0.07792432753458217 1.0885990175692345e-15 BR00117021 PTPN2 shuffled orf O15 A549 48 5775 Apoptosis -0.07344432443942996 3.054981078898606e-15 BR00117021 HCK shuffled orf O01 A549 48 6310 Apoptosis -0.07723905875767406 3.3876599640689957e-15 BR00117021 NTRK1 shuffled orf P02 A549 48 5690 Apoptosis -0.07502175805047867 1.7636457557401718e-14 BR00117021 S1PR1 shuffled orf L01 A549 48 5745 Apoptosis -0.10316318601080424 2.321536151670451e-17 BR00117021 DYRK1B shuffled orf M12 A549 48 3650 Binuclear -0.08007699711260828 6.602287384139686e-15 BR00117021 FPR1 shuffled orf L04 A549 48 5195 Binuclear -0.09117232519919283 1.2274635860895527e-14 BR00117020 CDK4 shuffled orf B21 A549 48 3920 Binuclear -0.06954212403487231 2.0315583387325437e-12 BR00117021 ADA shuffled orf P03 A549 48 5700 Binuclear -0.07470232913794927 3.4281413414165895e-12 BR00117021 FFAR4 shuffled orf C17 A549 48 4840 Binuclear -0.0697282099343955 1.0661624002952842e-11 BR00117021 PLK1 shuffled orf L11 A549 48 5335 Binuclear -0.07086156824782187 1.0693139109676086e-11 BR00117021 CCND1 shuffled orf B11 A549 48 5165 Binuclear -0.07812594905882016 1.532627560072592e-11 BR00117021 GJB4 shuffled orf H23 A549 48 4180 Binuclear -0.08184452489359031 2.3620494265007006e-11 BR00117021 UGT1A9 shuffled orf E24 A549 48 3745 Binuclear -0.07166666666666667 3.8561804701723093e-11 BR00117020 AKR1C1 shuffled orf A24 A549 48 4800 Binuclear -0.11385767790262172 1.493924195607663e-30 BR00117021 HPGDS shuffled orf O24 A549 48 5340 Elongated -0.07172519143027749 1.7039502102537364e-11 BR00117021 SCNN1G shuffled orf A04 A549 48 4930 Elongated -0.07016520894071915 1.961257022489658e-11 BR00117020 PRKCE shuffled orf L14 A549 48 5145 Elongated -0.0641523360015927 4.774628050349201e-10 BR00117021 CSK shuffled orf B04 A549 48 5370 Elongated -0.07013404039466951 3.4094465532412057e-09 BR00117020 P2RY12 shuffled orf B24 A549 48 4085 Elongated -0.0684961893389318 4.564173089491672e-09 BR00117020 GPR119 shuffled orf N23 A549 48 4215 Elongated -0.06151250693076448 6.437276914781075e-09 BR00117021 LPAR1 shuffled orf B05 A549 48 5160 Elongated -0.06216227805109709 8.416011296256316e-09 BR00117021 P3H1 shuffled orf P24 A549 48 4970 Elongated -0.06147670465906819 1.1947677481253345e-08 BR00117020 FFAR4 shuffled orf C17 A549 48 5000 Elongated -0.06482593157323921 1.3146180540914713e-08 BR00117020 CACNB4 shuffled orf A18 A549 48 4470 Elongated -0.1006896551724138 8.314407433141113e-23 BR00117020 LCK shuffled orf B18 A549 48 5075 Grape -0.09027863263166926 6.860231464519669e-17 BR00117021 MMP2 shuffled orf F06 A549 48 4630 Grape -0.086144578313253 1.7097798649467984e-16 BR00117020 CYP1A2 shuffled orf F21 A549 48 4980 Grape -0.08014981273408239 2.4453859018122253e-15 BR00117021 HPGDS shuffled orf O24 A549 48 5340 Grape -0.0798546065288143 5.013410866374887e-14 BR00117021 RPL3 shuffled orf G09 A549 48 4895 Grape -0.07482786228983186 1.2757151963864308e-12 BR00117021 LYN shuffled orf M05 A549 48 5000 Grape -0.07990814571502702 1.851353930644604e-12 BR00117020 PTK2B shuffled orf N19 A549 48 4325 Grape -0.06533620140016638 3.830599156902094e-12 BR00117021 HCK shuffled orf O01 A549 48 6310 Grape -0.06628185818694066 8.768910568852605e-12 BR00117021 OPRL1 shuffled orf O16 A549 48 5940 Grape -0.07526773600989303 1.820825091341491e-11 BR00117020 CACNB4 shuffled orf A18 A549 48 4470 Grape -0.11861946058111779 6.119181310568565e-32 BR00117021 USP1 shuffled orf G11 A549 48 5130 Hole -0.09643314319573312 9.698747067419181e-21 BR00117021 KCTD16 shuffled orf M22 A549 48 5005 Hole -0.09398986487921536 4.148624057389134e-19 BR00117021 IL1B shuffled orf E15 A549 48 4850 Hole -0.09730006340457611 7.057400028122568e-19 BR00117021 S1PR2 shuffled orf B06 A549 48 4475 Hole -0.08626262626262626 1.9314732730476413e-16 BR00117021 CHRM3 shuffled orf A11 A549 48 4950 Hole -0.09135375336715999 8.364250134773282e-16 BR00117021 JAK1 shuffled orf D18 A549 48 4230 Hole -0.09614816072100599 1.0285022680138619e-15 BR00117021 PDE7A shuffled orf J11 A549 48 3790 Hole -0.08479166666666667 1.981493431964993e-15 BR00117021 RNASE1 shuffled orf G17 A549 48 4800 Hole -0.07852650494159928 2.4195422082691527e-15 BR00117020 NTRK1 shuffled orf D01 A549 48 5565 Hole -0.08923889039397746 3.0242274441164915e-15 BR00117021 S100B shuffled orf I09 A549 48 4275 Hole -0.07747227409305317 1.6801109270210357e-14 BR00117021 FOXM1 shuffled orf P15 A549 48 5385 Interphase -0.0687777337059139 4.116997764004509e-11 BR00117020 BRAF shuffled orf C05 A549 48 5190 Interphase -0.06313827181601142 1.298436302922087e-10 BR00117021 BTK shuffled orf N01 A549 48 5855 Interphase -0.06923879040667362 2.0456592555740697e-10 BR00117020 TNF shuffled orf C13 A549 48 4795 Interphase -0.06959662740226683 2.122037477763548e-10 BR00117021 AKT1 shuffled orf J16 A549 48 4720 Interphase -0.07357090803593323 2.930215961677355e-10 BR00117020 DYRK1B shuffled orf M12 A549 48 4170 Interphase -0.06636175520702392 5.495540336828735e-10 BR00117021 CYP1A2 shuffled orf N12 A549 48 4980 Interphase -0.06991101479551612 5.998641471709361e-10 BR00117020 CACNB4 shuffled orf A18 A549 48 4470 Interphase -0.06493512125732921 1.7971519507022029e-09 BR00117020 RPL3 shuffled orf G09 A549 48 4920 Interphase -0.06235235731284462 2.6705334174160145e-09 BR00117021 HBB shuffled orf M11 A549 48 5230 Interphase -0.09437652811735942 2.8730361016810147e-16 BR00117021 CHRM3 shuffled orf A10 A549 48 4090 Large -0.08541237595955814 6.694285007760298e-13 BR00117020 CDK4 shuffled orf B21 A549 48 3920 Large -0.07017086261435923 3.494642635627545e-12 BR00117021 SSTR2 shuffled orf D02 A549 48 5480 Large -0.07100541998502484 4.186103500215036e-12 BR00117020 CSF1R shuffled orf J07 A549 48 5310 Large -0.07441367144375116 4.9900300434050674e-12 BR00117020 TNF shuffled orf C18 A549 48 4815 Large -0.06775112986788026 5.493118033790367e-12 BR00117021 PTPN2 shuffled orf O15 A549 48 5775 Large -0.06615893651645127 3.002479179595631e-10 BR00117020 IGF1R shuffled orf H05 A549 48 5160 Large -0.0625824494511007 3.0502106318811596e-10 BR00117020 TUBB3 shuffled orf K05 A549 48 5760 Large -0.07910120569967118 3.6761869767905917e-10 BR00117021 GHSR shuffled orf C24 A549 48 3565 Large -0.06550710442822419 7.776510391069254e-10 BR00117020 CDK2 shuffled orf L03 A549 48 5035 Large -0.10205992509363296 1.2722636235013013e-24 BR00117021 HPGDS shuffled orf O24 A549 48 5340 Metaphase -0.08388615577103226 3.1316149750234695e-14 BR00117020 ABL1 shuffled orf M24 A549 48 4505 Metaphase -0.07702814026782834 5.642045823781331e-14 BR00117021 TUBB4B shuffled orf E07 A549 48 5235 Metaphase -0.08329621380846325 5.719668098475624e-14 BR00117021 CACNG1 shuffled orf E23 A549 48 4490 Metaphase -0.08230477933664201 2.492196553692074e-13 BR00117021 KCNJ1 shuffled orf M03 A549 48 4365 Metaphase -0.07949609278565488 2.301268700431765e-12 BR00117021 ANXA1 shuffled orf N24 A549 48 4335 Metaphase -0.072 2.075706039678345e-11 BR00117021 CA14 shuffled orf N07 A549 48 4875 Metaphase -0.06831397898503692 4.50289997646797e-11 BR00117021 HBB shuffled orf M11 A549 48 5230 Metaphase -0.07419454420136452 8.66289684977727e-10 BR00117021 HSD11B1 shuffled orf G23 A549 48 3905 Metaphase -0.060088888888888886 2.9919855292150203e-09 BR00117021 CSK shuffled orf P05 A549 48 5625 Metaphase -0.09623381382522007 7.091325663733239e-18 BR00117020 PTK2B shuffled orf N19 A549 48 4325 MetaphaseAlignment -0.090282131661442 2.194925402949817e-17 BR00117020 PAK1 shuffled orf L12 A549 48 4785 MetaphaseAlignment -0.08411049682619459 4.3773978396811647e-16 BR00117020 PTK2B shuffled orf J18 A549 48 5080 MetaphaseAlignment -0.08765259092495206 1.1692385943036146e-15 BR00117020 CDK9 shuffled orf N22 A549 48 4545 MetaphaseAlignment -0.08372811049520955 1.2515964460513354e-15 BR00117020 HSP90AA1 shuffled orf C14 A549 48 4985 MetaphaseAlignment -0.07958953998000824 3.564080603301241e-15 BR00117020 PPARD shuffled orf I12 A549 48 5350 MetaphaseAlignment -0.08295655085658434 1.6029267319574275e-14 BR00117020 MET shuffled orf C08 A549 48 4700 MetaphaseAlignment -0.08093770039290632 3.998491414401822e-14 BR00117020 KCTD16 shuffled orf K21 A549 48 4790 MetaphaseAlignment -0.0721257753598613 8.005833934521064e-13 BR00117020 FOXM1 shuffled orf P15 A549 48 5470 MetaphaseAlignment -0.07585419504312997 3.1852587115075345e-12 BR00117020 SLC7A11 shuffled orf G24 A549 48 4705 MetaphaseAlignment -0.11521116275848936 1.0661140692197452e-25 BR00117021 KCNJ1 shuffled orf M03 A549 48 4365 OutOfFocus -0.10262172284644194 6.870511728435142e-25 BR00117021 HPGDS shuffled orf O24 A549 48 5340 OutOfFocus -0.07979150433135514 6.1898584547886974e-18 BR00117021 HCK shuffled orf O01 A549 48 6310 OutOfFocus -0.0847843513038668 8.874850741794585e-16 BR00117021 RPL3 shuffled orf G09 A549 48 4895 OutOfFocus -0.08330972313707583 1.491183533302102e-15 BR00117020 SLC29A1 shuffled orf N03 A549 48 5010 OutOfFocus -0.08601849584251711 4.10867812432611e-14 BR00117021 DYRK1B shuffled orf G13 A549 48 4245 OutOfFocus -0.07912735763191939 5.388429133628101e-14 BR00117021 P3H1 shuffled orf P24 A549 48 4970 OutOfFocus -0.08019710754745837 2.0461615741665535e-13 BR00117021 MMP2 shuffled orf F06 A549 48 4630 OutOfFocus -0.07371428571428572 7.97376886502152e-13 BR00117021 KCNH7 shuffled orf O07 A549 48 5250 OutOfFocus -0.07436014623492185 8.665186238232391e-13 BR00117021 USP1 shuffled orf G11 A549 48 5130 OutOfFocus -0.11568712766161231 2.249833700374068e-25 BR00117021 S100B shuffled orf I09 A549 48 4275 Polylobed -0.09774589243189001 4.796813719678201e-19 BR00117021 S1PR2 shuffled orf B06 A549 48 4475 Polylobed -0.0853932584269663 2.3489399900139097e-17 BR00117021 HPGDS shuffled orf O24 A549 48 5340 Polylobed -0.0813277828829442 1.0135542703045061e-15 BR00117020 CSF1R shuffled orf J07 A549 48 5310 Polylobed -0.07961039444537518 1.861326623601895e-14 BR00117020 PTK2B shuffled orf J18 A549 48 5080 Polylobed -0.07603656489780383 2.0547580870833697e-12 BR00117021 KCNK1 shuffled orf M15 A549 48 4765 Polylobed -0.08026817707643628 2.4963313422615554e-12 BR00117021 JAK1 shuffled orf D18 A549 48 4230 Polylobed -0.07719873451252243 1.8627992921390722e-11 BR00117021 DYRK1B shuffled orf G13 A549 48 4245 Polylobed -0.07210743801652893 2.309059433843705e-11 BR00117020 CHRM2 shuffled orf B03 A549 48 4840 Polylobed -0.0716301572940162 2.828617600718445e-11 BR00117021 IL1B shuffled orf E15 A549 48 4850 Polylobed -0.10398070899524679 8.189311363356157e-21 BR00117020 PTK2B shuffled orf N19 A549 48 4325 Prometaphase -0.08865303994855758 2.576971603470144e-19 BR00117020 SCNN1G shuffled orf O03 A549 48 5515 Prometaphase -0.07806709747346903 9.020206687440753e-15 BR00117020 AVPR1A shuffled orf D07 A549 48 5400 Prometaphase -0.07974304707209949 1.0589322729722186e-14 BR00117021 LPAR1 shuffled orf B05 A549 48 5160 Prometaphase -0.07497673119511597 1.0512515634037014e-12 BR00117021 FGF1 shuffled orf F03 A549 48 5020 Prometaphase -0.06989351403678606 2.1638512910993515e-11 BR00117021 CCND1 shuffled orf B11 A549 48 5165 Prometaphase -0.07055942082221137 2.2066930104324387e-11 BR00117020 HCK shuffled orf O20 A549 48 5055 Prometaphase -0.06851935342521913 7.400581086219896e-11 BR00117020 CA14 shuffled orf J14 A549 48 5105 Prometaphase -0.06970618034447822 7.580929495794328e-11 BR00117020 BTK shuffled orf P10 A549 48 4935 Prometaphase -0.07276282389067361 2.0745727828333704e-10 BR00117020 ANXA1 shuffled orf N24 A549 48 4325 Prometaphase -0.1079937625261769 5.51365460523773e-22 BR00117021 DYRK1B shuffled orf G13 A549 48 4245 SmallIrregular -0.08838951310861423 1.4466571460286346e-18 BR00117021 HPGDS shuffled orf O24 A549 48 5340 SmallIrregular -0.09575763475968667 2.43209448966508e-18 BR00117021 S1PR2 shuffled orf B06 A549 48 4475 SmallIrregular -0.09477784327336827 6.613501869237563e-17 BR00117020 GPR119 shuffled orf N23 A549 48 4215 SmallIrregular -0.09346388948728997 1.6881326659952152e-16 BR00117021 VEGFA shuffled orf B09 A549 48 4220 SmallIrregular -0.09650546892196764 3.422051928228974e-16 BR00117021 MET shuffled orf C08 A549 48 3890 SmallIrregular -0.08222952538624534 6.299736493577334e-15 BR00117021 SCNN1G shuffled orf A04 A549 48 4930 SmallIrregular -0.07816345325516272 2.5226263666305076e-14 BR00117021 PRKCB shuffled orf K14 A549 48 5220 SmallIrregular -0.0754410919026324 3.7814732640391135e-14 BR00117021 EZH2 shuffled orf D03 A549 48 5535 SmallIrregular -0.07629960135630498 2.0856861563083774e-13 BR00117021 DNMT3A shuffled orf H07 A549 48 5115 SmallIrregular -0.5048181388757675 2.6756339500922254e-17 BR00118049 P3H1 shuffled orf P24 A549 96 145 ADCCM -0.0817678648211002 1.1834453007717073e-15 BR00118050 COMT shuffled orf B10 A549 96 5225 ADCCM -0.07091968287779768 1.4800671673577511e-15 BR00117006 ADA shuffled orf P03 A549 96 6910 ADCCM -0.0792053590559394 5.000618731431795e-14 BR00118050 KCTD16 shuffled orf K21 A549 96 4975 ADCCM -0.06473771111081206 1.1296309099567122e-13 BR00118050 F10 shuffled orf I04 A549 96 7265 ADCCM -0.06762765945559512 2.2964985230097877e-13 BR00117006 PDPK1 shuffled orf D06 A549 96 6485 ADCCM -0.06368082208099611 1.0754123267278532e-12 BR00117006 KDR shuffled orf O02 A549 96 6945 ADCCM -0.051751879302057824 2.1455097591619014e-12 BR00118050 HDAC3 shuffled orf N21 A549 96 10275 ADCCM -0.07506791843201105 2.2798495220158243e-12 BR00117006 KCNMA1 shuffled orf O08 A549 96 4865 ADCCM -0.05582265486959667 4.0140376806973426e-12 BR00117006 LPAR1 shuffled orf B05 A549 96 8610 ADCCM -0.08789083266733594 1.1318311761089384e-27 BR00118050 ALDH2 shuffled orf P13 A549 96 8095 Anaphase -0.08108816045502171 6.202417076703446e-26 BR00117006 HTR3A shuffled orf J23 A549 96 8910 Anaphase -0.08100241108257725 4.209749542444754e-24 BR00117006 JAK1 shuffled orf H17 A549 96 8280 Anaphase -0.11219917898945506 1.2224458066990664e-22 BR00117006 MMP2 shuffled orf F06 A549 96 4050 Anaphase -0.06896915173664342 1.9528128191166376e-22 BR00118050 TBXAS1 shuffled orf P23 A549 96 10635 Anaphase -0.0682616597655312 1.8769757449002038e-19 BR00118050 ITGB2 shuffled orf P21 A549 96 9380 Anaphase -0.06961919186320999 3.815163786248395e-18 BR00118050 ANXA1 shuffled orf N24 A549 96 8395 Anaphase -0.08660539686784442 5.876729759540396e-18 BR00117006 AKR1C1 shuffled orf A24 A549 96 5360 Anaphase -0.0746390506502806 8.222497277503681e-17 BR00117006 CYP3A4 shuffled orf K22 A549 96 6755 Anaphase -0.4903637222484648 2.6283237787284366e-16 BR00118049 P3H1 shuffled orf P24 A549 96 145 Anaphase -0.0919502883061254 3.0694579864467924e-38 BR00118050 HDAC3 shuffled orf N21 A549 96 10275 Apoptosis -0.10862635142729557 6.445693385123872e-30 BR00118050 DYRK1B shuffled orf M12 A549 96 5735 Apoptosis -0.08259819160055952 7.73600170636665e-29 BR00117006 GPR119 shuffled orf N23 A549 96 9560 Apoptosis -0.08268690476471642 1.634533847305802e-28 BR00118050 AURKB shuffled orf L19 A549 96 9430 Apoptosis -0.09181450357920946 3.1162214577193197e-26 BR00117006 PARP3 shuffled orf J20 A549 96 7020 Apoptosis -0.09145087797288286 2.8910785856863257e-24 BR00117006 PNLIP shuffled orf L22 A549 96 6545 Apoptosis -0.07568750591266 8.4337941493544e-24 BR00118050 ITGB2 shuffled orf P21 A549 96 9380 Apoptosis -0.586679263108172 1.268118436372891e-23 BR00118049 P3H1 shuffled orf P24 A549 96 145 Apoptosis -0.12478043570487582 1.0787402204680895e-22 BR00118050 DYRK1B shuffled orf G13 A549 96 3280 Apoptosis -0.07444451862478133 5.112160594955222e-22 BR00117006 PDE7A shuffled orf J11 A549 96 8955 Apoptosis -0.10685929557175722 1.5905775505863055e-51 BR00118050 HDAC3 shuffled orf N21 A549 96 10275 Binuclear -0.11007462686567164 8.13905724367273e-43 BR00118050 BRD4 shuffled orf N17 A549 96 8040 Binuclear -0.12157592834859615 4.072666280844458e-34 BR00118050 COMT shuffled orf B10 A549 96 5225 Binuclear -0.08512489446437162 3.400725491122603e-30 BR00118050 AURKB shuffled orf L19 A549 96 9430 Binuclear -0.0850925012916888 5.5090343076003025e-30 BR00118050 ITGB2 shuffled orf P21 A549 96 9380 Binuclear -0.08994151192277773 5.7353189197876565e-30 BR00118050 PDE7A shuffled orf J11 A549 96 8380 Binuclear -0.0813583736883402 7.98396398497374e-30 BR00117006 BRD4 shuffled orf N17 A549 96 10205 Binuclear -0.09363684087700315 2.1451682631113897e-28 BR00118050 PDPK1 shuffled orf H15 A549 96 7325 Binuclear -0.0912303664921466 4.453283779729468e-28 BR00118050 PTK2B shuffled orf N19 A549 96 7640 Binuclear -0.088 8.740394684184648e-28 BR00118050 HTR3A shuffled orf J23 A549 96 8125 Binuclear -0.46953235710911667 6.0369999564344356e-15 BR00118049 P3H1 shuffled orf P24 A549 96 145 Elongated -0.08041856876486851 3.305190934046794e-13 BR00118050 GPR55 shuffled orf F13 A549 96 4530 Elongated -0.054634631156389 6.37053612162668e-12 BR00117006 ALDH2 shuffled orf P13 A549 96 8835 Elongated -0.10913348946135831 1.731092522190661e-11 BR00118050 ANXA1 shuffled orf D23 A549 96 2135 Elongated -0.06965239847036835 1.749567732894196e-11 BR00118050 AKT1 shuffled orf J16 A549 96 5220 Elongated -0.05175209439358524 2.1831155262399924e-10 BR00117006 GAA shuffled orf N15 A549 96 8550 Elongated -0.07056258562912308 6.803654300612224e-10 BR00118050 ITGB2 shuffled orf B12 A549 96 4370 Elongated -0.05902023691012504 1.0226338601457728e-09 BR00118050 MAPK14 shuffled orf G22 A549 96 6110 Elongated -0.05424788061535217 1.0585503145024263e-09 BR00118050 HSD11B1 shuffled orf C02 A549 96 7235 Elongated -0.053536659448044255 1.8161600967460736e-09 BR00117006 ABL1 shuffled orf C01 A549 96 7255 Elongated -0.08983806985055343 8.62458686226242e-38 BR00118050 TBXAS1 shuffled orf P23 A549 96 10635 Grape -0.0964262693794201 1.629596591897604e-36 BR00117006 HTR3A shuffled orf J23 A549 96 8910 Grape -0.08895309764753187 2.2917518874088402e-33 BR00117006 GPR119 shuffled orf N23 A549 96 9560 Grape -0.08796303950257475 3.666091140780444e-32 BR00118050 AURKB shuffled orf L19 A549 96 9430 Grape -0.08643535734297794 6.386904963084404e-31 BR00118050 ITGB2 shuffled orf P21 A549 96 9380 Grape -0.08757585637301882 1.3793965214817747e-29 BR00117006 PTK2B shuffled orf N19 A549 96 8725 Grape -0.0862007531481431 5.010307689864117e-29 BR00117006 ALDH2 shuffled orf P13 A549 96 8835 Grape -0.0877629492528913 1.6918031380331493e-28 BR00118050 PDE7A shuffled orf J11 A549 96 8380 Grape -0.08091821691821692 7.3846730089730485e-28 BR00117006 HDAC3 shuffled orf N21 A549 96 9620 Grape -0.12314700361671932 3.407655927403769e-27 BR00117006 MMP2 shuffled orf F06 A549 96 4050 Grape -0.1361681486829806 7.843667533413817e-37 BR00117006 DNMT3A shuffled orf F04 A549 96 4495 Hole -0.13427720948138372 2.707810255412351e-33 BR00117006 CA5A shuffled orf B23 A549 96 4180 Hole -0.12564503376808359 3.7183687245769607e-31 BR00118050 LCK shuffled orf B18 A549 96 4460 Hole -0.11371988426782947 6.69255449479284e-31 BR00117006 SIRT2 shuffled orf G02 A549 96 5400 Hole -0.09638920397159594 1.5005256935598313e-28 BR00117006 KDR shuffled orf O02 A549 96 6945 Hole -0.11257606490872211 1.2929939186945188e-27 BR00118050 GHSR shuffled orf A17 A549 96 4930 Hole -0.09449572696767705 2.7479060799459325e-27 BR00117006 KCNQ2 shuffled orf K01 A549 96 6915 Hole -0.08491419513078634 1.2963562718569012e-23 BR00117006 SSTR2 shuffled orf D02 A549 96 7390 Hole -0.08645155687045784 1.865737359050738e-23 BR00117006 FOXM1 shuffled orf J02 A549 96 7070 Hole -0.09473684210526316 2.0433561429443973e-23 BR00117006 NTRK1 shuffled orf D01 A549 96 5890 Hole -0.12642672209459213 8.783878656571422e-20 BR00118050 LPAR1 shuffled orf B20 A549 96 2770 Interphase -0.08166653403011734 1.9208685331488322e-19 BR00118050 HCK shuffled orf O01 A549 96 6555 Interphase -0.07988644489727888 2.1288362438447743e-17 BR00118050 P3H1 shuffled orf P24 A549 96 6100 Interphase -0.08456457012742574 2.3133415717755933e-17 BR00117006 TNF shuffled orf C13 A549 96 5440 Interphase -0.08717157792178916 6.715038081125229e-17 BR00118050 KCTD16 shuffled orf K21 A549 96 4975 Interphase -0.07512098776684831 6.818357212953203e-17 BR00117006 DCK shuffled orf D05 A549 96 6690 Interphase -0.07718405428329092 1.0846026210881104e-15 BR00118050 PORCN shuffled orf N11 A549 96 5895 Interphase -0.06994052687433161 2.3006127873551413e-14 BR00117006 TGM2 shuffled orf H02 A549 96 6535 Interphase -0.08843260235926079 3.153797720349256e-14 BR00117006 MMP2 shuffled orf F06 A549 96 4050 Interphase -0.08480587939964201 3.736987765292213e-14 BR00118050 ITGB2 shuffled orf B12 A549 96 4370 Interphase -0.09175392670157068 2.1376353553527584e-28 BR00118050 PTK2B shuffled orf N19 A549 96 7640 Large -0.07966121606243029 7.461652014063459e-27 BR00117006 GPR119 shuffled orf N23 A549 96 9560 Large -0.08361660202329896 5.860328776336426e-26 BR00118050 PDE7A shuffled orf J11 A549 96 8380 Large -0.0838346609527627 2.1304958838118646e-24 BR00118050 GJB4 shuffled orf H23 A549 96 7840 Large -0.0873174481168332 5.44293871328925e-22 BR00117006 TUBB3 shuffled orf G06 A549 96 6505 Large -0.06894833704894199 1.1275137648987913e-21 BR00118050 HDAC3 shuffled orf N21 A549 96 10275 Large -0.07078516078516078 2.0849662563266273e-21 BR00117006 HDAC3 shuffled orf N21 A549 96 9620 Large -0.07363611201675267 5.08362161647582e-21 BR00117006 PTK2B shuffled orf N19 A549 96 8725 Large -0.07152317880794702 1.4344724437109357e-20 BR00117006 ASIC1 shuffled orf L21 A549 96 9060 Large -0.08802975796412336 4.2622798776664863e-20 BR00118050 IGF1R shuffled orf N16 A549 96 5830 Large -0.09223681579588695 7.556357032349684e-36 BR00117006 GPR119 shuffled orf N23 A549 96 9560 Metaphase -0.08884421349850594 7.552573850345511e-33 BR00118050 AURKB shuffled orf L19 A549 96 9430 Metaphase -0.08322295805739514 1.0446403495298926e-27 BR00117006 ASIC1 shuffled orf L21 A549 96 9060 Metaphase -0.1042168712785768 6.289999016364638e-22 BR00117006 CDK4 shuffled orf P20 A549 96 4535 Metaphase -0.07353518360008444 5.891447087304271e-21 BR00117006 PTK2B shuffled orf N19 A549 96 8725 Metaphase -0.07491054035816898 6.46028387125712e-21 BR00118050 PDE7A shuffled orf J11 A549 96 8380 Metaphase -0.076921808041023 1.6447356612082947e-20 BR00117006 FPR1 shuffled orf D21 A549 96 7805 Metaphase -0.06901466101466101 2.2626939298011646e-20 BR00117006 HDAC3 shuffled orf N21 A549 96 9620 Metaphase -0.07911217507428873 1.5523871312541731e-19 BR00117006 PARP3 shuffled orf J20 A549 96 7020 Metaphase -0.07156253624586566 1.7201984654972103e-19 BR00117006 CDK9 shuffled orf H11 A549 96 8545 Metaphase -0.1237534376847354 2.588859358780147e-29 BR00118050 FLT3 shuffled orf K13 A549 96 4320 MetaphaseAlignment -0.1064031744970556 6.78711534899835e-27 BR00117006 AKR1C1 shuffled orf A24 A549 96 5360 MetaphaseAlignment -0.08865228107999067 4.780417401724023e-24 BR00118050 SLCO2B1 shuffled orf A02 A549 96 6900 MetaphaseAlignment -0.09017803596580741 3.138920281514859e-20 BR00118050 AKR1C1 shuffled orf A24 A549 96 5590 MetaphaseAlignment -0.10305997552019584 2.6703717263453273e-19 BR00118050 ADORA2A shuffled orf O18 A549 96 4085 MetaphaseAlignment -0.0814457287680516 8.74435380515411e-18 BR00118050 KCNN4 shuffled orf A06 A549 96 6015 MetaphaseAlignment -0.49759093056211623 8.817248417549367e-17 BR00118049 P3H1 shuffled orf P24 A549 96 145 MetaphaseAlignment -0.06638418795244033 6.622498992465991e-16 BR00118050 DDR2 shuffled orf M02 A549 96 8070 MetaphaseAlignment -0.06887632480632389 2.2324277427209247e-15 BR00117006 TGFBR1 shuffled orf I23 A549 96 7235 MetaphaseAlignment -0.08404157359011617 6.991383294027106e-15 BR00117006 HSP90AB1 shuffled orf P01 A549 96 4705 MetaphaseAlignment -0.1163355408388521 8.531823601672342e-54 BR00117006 ASIC1 shuffled orf L21 A549 96 9060 OutOfFocus -0.1103091300153661 2.829767312289544e-47 BR00117006 ALDH2 shuffled orf P13 A549 96 8835 OutOfFocus -0.11357412768325505 6.1307896384741795e-46 BR00118050 ALDH2 shuffled orf P13 A549 96 8095 OutOfFocus -0.10217439071652512 5.966381235762474e-41 BR00117006 HTR3A shuffled orf J23 A549 96 8910 OutOfFocus -0.09751140531607831 5.452069331049227e-40 BR00117006 GPR119 shuffled orf N23 A549 96 9560 OutOfFocus -0.10465700132982991 6.261917091988888e-40 BR00117006 JAK1 shuffled orf H17 A549 96 8280 OutOfFocus -0.08825299694701483 1.755713719029034e-36 BR00118050 TBXAS1 shuffled orf P23 A549 96 10635 OutOfFocus -0.09549139963040877 1.5500945100079646e-35 BR00117006 CHRM2 shuffled orf B03 A549 96 8835 OutOfFocus -0.09151583551583552 1.610595370112656e-35 BR00117006 HDAC3 shuffled orf N21 A549 96 9620 OutOfFocus -0.0953061372886237 3.402021603805141e-34 BR00117006 CDK9 shuffled orf H11 A549 96 8545 OutOfFocus -0.10372189728183318 5.335783536123186e-32 BR00117006 S100B shuffled orf I09 A549 96 6735 Polylobed -0.08723684210526315 1.4190434373793276e-25 BR00118050 JAK1 shuffled orf H17 A549 96 7600 Polylobed -0.09189989619544525 8.55145822163983e-24 BR00117006 MAPK8 shuffled orf I14 A549 96 6350 Polylobed -0.08186200931263628 1.0444070390357168e-20 BR00117006 KDR shuffled orf O02 A549 96 6945 Polylobed -0.08896434634974533 1.0723103853595795e-20 BR00117006 NTRK1 shuffled orf D01 A549 96 5890 Polylobed -0.07538861376927156 1.209242593593862e-19 BR00117006 FLT3 shuffled orf K13 A549 96 7765 Polylobed -0.07640980054650963 3.088163413334275e-19 BR00117006 SSTR2 shuffled orf D02 A549 96 7390 Polylobed -0.09739504991957312 5.379257646133459e-19 BR00117006 DNMT3A shuffled orf F04 A549 96 4495 Polylobed -0.0816438757734633 2.7348783907295806e-18 BR00117006 GUCY1B1 shuffled orf J08 A549 96 6160 Polylobed -0.07817021062569121 6.197481516290983e-18 BR00117006 ATM shuffled orf C04 A549 96 6575 Polylobed -0.10974085640116174 4.246289381995646e-23 BR00118050 FLT3 shuffled orf K13 A549 96 4320 Prometaphase -0.10320768012885631 3.0441854949712913e-19 BR00118050 HSD11B1 shuffled orf G23 A549 96 4050 Prometaphase -0.0808378588052754 9.806318221618632e-19 BR00117006 HSD11B1 shuffled orf G23 A549 96 6445 Prometaphase -0.07656520194725952 1.977172528229797e-16 BR00118050 HDAC6 shuffled orf E20 A549 96 6270 Prometaphase -0.08097573814499735 2.1552166851968754e-16 BR00118050 AKR1C1 shuffled orf A24 A549 96 5590 Prometaphase -0.07337367624810892 6.813969194224478e-16 BR00117006 OPRL1 shuffled orf A23 A549 96 6610 Prometaphase -0.07203802772541161 8.253091257102522e-14 BR00118050 FFAR2 shuffled orf B15 A549 96 5920 Prometaphase -0.07850569760441005 6.183374574971387e-13 BR00117006 GPR119 shuffled orf N02 A549 96 4660 Prometaphase -0.0832313341493268 9.96233477831487e-13 BR00118050 ADORA2A shuffled orf O18 A549 96 4085 Prometaphase -0.07363083164300203 4.82924846726532e-12 BR00118050 GHSR shuffled orf A17 A549 96 4930 Prometaphase -0.10103302103302103 3.4851095307399005e-43 BR00117006 HDAC3 shuffled orf N21 A549 96 9620 SmallIrregular -0.09645650739798323 1.5595807831986288e-36 BR00117006 HTR3A shuffled orf J23 A549 96 8910 SmallIrregular -0.09614991251666681 1.4885701509801467e-35 BR00117006 PTK2B shuffled orf N19 A549 96 8725 SmallIrregular -0.08472994766702384 2.685864971708936e-30 BR00117006 GPR119 shuffled orf N23 A549 96 9560 SmallIrregular -0.12809748355689848 2.1389408427450895e-29 BR00117006 MMP2 shuffled orf F06 A549 96 4050 SmallIrregular -0.10134983127109111 7.465333116202115e-29 BR00117006 MAPK8 shuffled orf I14 A549 96 6350 SmallIrregular -0.09617343457861327 1.4244613908332424e-27 BR00117006 S100B shuffled orf I09 A549 96 6735 SmallIrregular -0.0883196873316346 4.8585864004209785e-27 BR00118050 GJB4 shuffled orf H23 A549 96 7840 SmallIrregular -0.08176426939736119 3.933948333854619e-25 BR00117006 AURKB shuffled orf L19 A549 96 8490 SmallIrregular -0.07527593818984547 9.666449473207753e-23 BR00117006 ASIC1 shuffled orf L21 A549 96 9060 SmallIrregular -0.13110516996484936 2.99125382870769e-36 BR00117023 SLC7A11 shuffled orf A03 U2OS 48 4780 ADCCM -0.12637843264988147 2.17959506040146e-34 BR00117023 TUBB3 shuffled orf G06 U2OS 48 4880 ADCCM -0.11744349353216071 1.0241959425922672e-33 BR00117023 DHH shuffled orf G05 U2OS 48 5540 ADCCM -0.1212890625 3.2530336008237996e-33 BR00117023 TUBB3 shuffled orf K05 U2OS 48 5120 ADCCM -0.12559311681907837 1.5593313146290887e-29 BR00117023 TUBB4B shuffled orf E04 U2OS 48 4225 ADCCM -0.09848681184758895 3.645689976925353e-22 BR00117023 GRIN2A shuffled orf A05 U2OS 48 5145 ADCCM -0.09375 3.2189737080110493e-21 BR00117023 CDC25A shuffled orf M04 U2OS 48 5440 ADCCM -0.09443781163988585 6.506623716065386e-20 BR00117023 CDK7 shuffled orf K06 U2OS 48 5015 ADCCM -0.09370949680017142 1.8701320411525155e-19 BR00117023 HRH4 shuffled orf O06 U2OS 48 4975 ADCCM -0.09669282793580246 5.224028694811507e-19 BR00117023 KCNN4 shuffled orf A06 U2OS 48 4565 ADCCM -0.12630982051078277 6.176653695796839e-39 BR00117023 DHH shuffled orf G05 U2OS 48 5540 Anaphase -0.12614909732957397 1.9039325387405923e-31 BR00117023 GABRB2 shuffled orf C06 U2OS 48 4475 Anaphase -0.1426403641881639 1.2314731037704841e-29 BR00117023 PTK2B shuffled orf J18 U2OS 48 3295 Anaphase -0.12861482817335318 3.191691775272601e-29 BR00117022 LYN shuffled orf M05 U2OS 48 3985 Anaphase -0.12860777217910918 1.3092447589172481e-27 BR00117023 PTK2B shuffled orf N19 U2OS 48 3770 Anaphase -0.10680147058823529 2.0107715576961665e-27 BR00117023 CDC25A shuffled orf M04 U2OS 48 5440 Anaphase -0.11146161934805468 3.931491269504761e-26 BR00117022 LYN shuffled orf C20 U2OS 48 4755 Anaphase -0.10613142138690233 7.381472220631747e-25 BR00117023 HRH4 shuffled orf O06 U2OS 48 4975 Anaphase -0.10999037784024185 7.370315117673388e-24 BR00117023 LYN shuffled orf C20 U2OS 48 4450 Anaphase -0.10496404002501564 1.7255346285251904e-23 BR00117023 LYN shuffled orf M05 U2OS 48 4800 Anaphase -0.36705521056024976 0.0 BR00117023 ADH1C shuffled orf O04 U2OS 48 5640 Apoptosis -0.4027573529411765 0.0 BR00117023 CDC25A shuffled orf M04 U2OS 48 5440 Apoptosis -0.4060788830160755 0.0 BR00117023 DHH shuffled orf G05 U2OS 48 5540 Apoptosis -0.39053715884329127 0.0 BR00117023 HRH4 shuffled orf O06 U2OS 48 4975 Apoptosis -0.3832882931007004 2.45207084353e-313 BR00117023 SLC7A11 shuffled orf A03 U2OS 48 4780 Apoptosis -0.3701171875 2.31703740284e-312 BR00117023 TUBB3 shuffled orf K05 U2OS 48 5120 Apoptosis -0.3584412284935093 5.031908338028587e-294 BR00117023 GRIN2A shuffled orf A05 U2OS 48 5145 Apoptosis -0.33949486571614695 6.321495171580616e-250 BR00117023 TUBB3 shuffled orf G06 U2OS 48 4880 Apoptosis -0.33145705512626294 3.0468078429479365e-244 BR00117023 CDK7 shuffled orf K06 U2OS 48 5015 Apoptosis -0.32464810830195445 2.440815143441441e-197 BR00117023 TUBB4B shuffled orf E04 U2OS 48 4225 Apoptosis -0.22192628179693913 1.3043698769479495e-108 BR00117023 CDK7 shuffled orf K06 U2OS 48 5015 Binuclear -0.2009173140585773 2.380978136660838e-98 BR00117023 DHH shuffled orf G05 U2OS 48 5540 Binuclear -0.20854635203370028 4.201463571602945e-95 BR00117023 HRH4 shuffled orf O06 U2OS 48 4975 Binuclear -0.21006933802242145 1.0311469492980616e-92 BR00117023 SLC7A11 shuffled orf A03 U2OS 48 4780 Binuclear -0.19119762386839653 1.121504018325214e-90 BR00117023 ADH1C shuffled orf O04 U2OS 48 5640 Binuclear -0.19810725301597004 1.0745264006779081e-88 BR00117023 GRIN2A shuffled orf A05 U2OS 48 5145 Binuclear -0.19692824426968253 2.6629524138658904e-83 BR00117023 TUBB3 shuffled orf G06 U2OS 48 4880 Binuclear -0.189453125 1.0338407318913698e-80 BR00117023 TUBB3 shuffled orf K05 U2OS 48 5120 Binuclear -0.1982808857808858 3.5322611792920046e-73 BR00117023 TUBB4B shuffled orf E04 U2OS 48 4225 Binuclear -0.16373173976517708 6.585615054408226e-54 BR00117023 KCNN4 shuffled orf A06 U2OS 48 4565 Binuclear -0.16333557852278693 5.228298422875755e-65 BR00117023 DHH shuffled orf G05 U2OS 48 5540 Elongated -0.15404411764705883 1.046553472935783e-56 BR00117023 CDC25A shuffled orf M04 U2OS 48 5440 Elongated -0.1535747927085144 1.1682783843359329e-51 BR00117023 HRH4 shuffled orf O06 U2OS 48 4975 Elongated -0.1408203125 1.1585881887118524e-44 BR00117023 TUBB3 shuffled orf K05 U2OS 48 5120 Elongated -0.13065451261784064 1.048893997175095e-38 BR00117023 GRIN2A shuffled orf A05 U2OS 48 5145 Elongated -0.12314871371422323 9.40969767729659e-38 BR00117023 ADH1C shuffled orf O04 U2OS 48 5640 Elongated -0.12542393939597452 6.057644782647004e-34 BR00117023 TUBB3 shuffled orf G06 U2OS 48 4880 Elongated -0.12324506631710692 1.2956489089371017e-33 BR00117023 CDK7 shuffled orf K06 U2OS 48 5015 Elongated -0.12410131162528394 1.50163406300089e-32 BR00117023 SLC7A11 shuffled orf A03 U2OS 48 4780 Elongated -0.12167083309400309 2.845993814239797e-29 BR00117023 GABRB2 shuffled orf C06 U2OS 48 4475 Elongated -0.08054545454545455 6.156108274252494e-16 BR00117022 DDR2 shuffled orf M02 U2OS 48 5500 Grape -0.08873117067615324 7.630511412710011e-14 BR00117022 PTK2B shuffled orf N19 U2OS 48 3915 Grape -0.07478591817316842 3.357623222955663e-13 BR00117023 PAK4 shuffled orf G10 U2OS 48 5255 Grape -0.07701899886046297 1.2394501959798873e-11 BR00117023 GPR55 shuffled orf H16 U2OS 48 4330 Grape -0.0703958262851445 3.728627334128389e-11 BR00117022 PAK4 shuffled orf M19 U2OS 48 4970 Grape -0.07139460673134013 4.670106538524129e-11 BR00117023 SLC7A11 shuffled orf A03 U2OS 48 4780 Grape -0.06849930251895922 6.178206655992967e-11 BR00117023 AKR1C1 shuffled orf I01 U2OS 48 5140 Grape -0.07016019121497338 8.083847098930554e-11 BR00117022 CDK2 shuffled orf L03 U2OS 48 4840 Grape -0.0652730992135877 2.001420070411234e-10 BR00117022 FFAR2 shuffled orf P06 U2OS 48 5385 Grape -0.06577424864851628 2.2278350313102225e-10 BR00117022 OPRL1 shuffled orf O16 U2OS 48 5270 Grape -0.09478655583329974 5.300759169932098e-20 BR00117023 ABL1 shuffled orf C01 U2OS 48 5005 Hole -0.08402568047024934 8.904865196806165e-18 BR00117023 ADH1C shuffled orf O04 U2OS 48 5640 Hole -0.09563920554921095 4.04127050845672e-17 BR00117022 FGF1 shuffled orf F22 U2OS 48 4190 Hole -0.08544451945972825 2.9789282114727722e-16 BR00117023 HRH4 shuffled orf O06 U2OS 48 4975 Hole -0.08103730305202249 2.9365703839162556e-13 BR00117023 GABRB2 shuffled orf C06 U2OS 48 4475 Hole -0.06918690942303947 1.3429983147134957e-10 BR00117023 TUBB3 shuffled orf G06 U2OS 48 4880 Hole -0.0648915299306051 2.0428416428418391e-10 BR00117022 ERBB2 shuffled orf E21 U2OS 48 5440 Hole -0.06420872705574888 2.28242785371332e-10 BR00117023 DHH shuffled orf G05 U2OS 48 5540 Hole -0.06977248104008667 3.443315218309218e-10 BR00117023 FGF1 shuffled orf F03 U2OS 48 4615 Hole -0.06629164968688588 4.901833802338724e-10 BR00117023 CDK7 shuffled orf K06 U2OS 48 5015 Hole -0.1512154014953567 1.0274782042994915e-56 BR00117023 ADH1C shuffled orf O04 U2OS 48 5640 Interphase -0.16511509324009324 8.893213537541129e-51 BR00117023 TUBB4B shuffled orf E04 U2OS 48 4225 Interphase -0.14681290260477295 1.238591542202145e-47 BR00117023 CDK7 shuffled orf K06 U2OS 48 5015 Interphase -0.1427734375 6.6690479671743105e-46 BR00117023 TUBB3 shuffled orf K05 U2OS 48 5120 Interphase -0.14926484099100978 8.693456417600578e-45 BR00117023 KCNN4 shuffled orf A06 U2OS 48 4565 Interphase -0.14232027546057505 1.0462797361425264e-42 BR00117023 SLC7A11 shuffled orf A03 U2OS 48 4780 Interphase -0.1299160203604376 3.5918276862203267e-41 BR00117023 DHH shuffled orf G05 U2OS 48 5540 Interphase -0.13782143840538344 7.525875756287348e-41 BR00117023 TUBB3 shuffled orf G06 U2OS 48 4880 Interphase -0.12877666141344693 1.2173921919806169e-37 BR00117023 GRIN2A shuffled orf A05 U2OS 48 5145 Interphase -0.14363837261938772 1.2233860476749513e-35 BR00117022 PTK2B shuffled orf N19 U2OS 48 3915 Interphase -0.17605563545603753 4.698418000521186e-46 BR00117022 PTK2B shuffled orf J18 U2OS 48 3365 Large -0.12738970588235293 7.248128736997033e-39 BR00117023 CDC25A shuffled orf M04 U2OS 48 5440 Large -0.18084895422870936 8.553259165092937e-38 BR00117023 HSD11B1 shuffled orf C02 U2OS 48 2615 Large -0.12951887353096941 8.52811703448777e-37 BR00117023 HRH4 shuffled orf O06 U2OS 48 4975 Large -0.11853710608769973 1.0465584692756484e-29 BR00117023 SLC7A11 shuffled orf A03 U2OS 48 4780 Large -0.13292111042399468 1.8587405669911508e-29 BR00117023 PTK2B shuffled orf N19 U2OS 48 3770 Large -0.11144765239299377 2.754031201762147e-28 BR00117023 GRIN2A shuffled orf A05 U2OS 48 5145 Large -0.13566009104704096 7.727519116447824e-27 BR00117023 PTK2B shuffled orf J18 U2OS 48 3295 Large -0.10314464163848262 1.3694711619013247e-26 BR00117023 ADH1C shuffled orf O04 U2OS 48 5640 Large -0.1036951823098179 2.2024386618477246e-26 BR00117023 DHH shuffled orf G05 U2OS 48 5540 Large -0.19939301972685888 1.0804867340293386e-57 BR00117023 PTK2B shuffled orf J18 U2OS 48 3295 Metaphase -0.12795115391999132 3.965529921536197e-36 BR00117023 ABL1 shuffled orf C01 U2OS 48 5005 Metaphase -0.1383134875635837 6.587426794442284e-32 BR00117023 PTK2B shuffled orf N19 U2OS 48 3770 Metaphase -0.12835392905424703 1.826016433432035e-26 BR00117022 ABL1 shuffled orf C01 U2OS 48 3625 Metaphase -0.12606971736418462 9.747532845734409e-24 BR00117022 PTK2B shuffled orf J18 U2OS 48 3365 Metaphase -0.10351437535857921 4.98540484440087e-20 BR00117023 ABL1 shuffled orf M24 U2OS 48 4190 Metaphase -0.09890393017088096 4.1788777347729515e-17 BR00117022 PTK2B shuffled orf N19 U2OS 48 3915 Metaphase -0.09452380952380952 9.578748665394458e-17 BR00117023 LPAR1 shuffled orf B20 U2OS 48 4200 Metaphase -0.08744643739350494 3.4822680231718664e-16 BR00117023 CLK1 shuffled orf J17 U2OS 48 4725 Metaphase -0.08422925916047987 6.112045962683042e-16 BR00117023 CDK7 shuffled orf K06 U2OS 48 5015 Metaphase -0.18877086494688922 1.0203815031774184e-51 BR00117023 PTK2B shuffled orf J18 U2OS 48 3295 MetaphaseAlignment -0.16245592633235242 6.758798907357288e-44 BR00117023 PTK2B shuffled orf N19 U2OS 48 3770 MetaphaseAlignment -0.15018509542589606 1.5686378553344827e-33 BR00117022 PTK2B shuffled orf J18 U2OS 48 3365 MetaphaseAlignment -0.11487393346754865 7.14555416755626e-29 BR00117023 PAK1 shuffled orf L12 U2OS 48 4940 MetaphaseAlignment -0.106640625 9.294586597064938e-26 BR00117023 TUBB3 shuffled orf K05 U2OS 48 5120 MetaphaseAlignment -0.11734791256336205 1.2648841983887536e-25 BR00117023 ABL1 shuffled orf M24 U2OS 48 4190 MetaphaseAlignment -0.11938349007314525 9.842229764420938e-25 BR00117022 PTK2B shuffled orf N19 U2OS 48 3915 MetaphaseAlignment -0.12157390658618786 8.56316091670122e-24 BR00117022 ABL1 shuffled orf C01 U2OS 48 3625 MetaphaseAlignment -0.12744692357689694 5.673681828644956e-23 BR00117022 HSD11B1 shuffled orf C02 U2OS 48 3175 MetaphaseAlignment -0.09463224531761186 1.739682956494123e-20 BR00117023 GRIN2A shuffled orf A05 U2OS 48 5145 MetaphaseAlignment -0.07727761876161951 7.359303331530096e-15 BR00117023 DHH shuffled orf G05 U2OS 48 5540 OutOfFocus -0.0778743961352657 4.559443360320593e-14 BR00117022 CLK1 shuffled orf D08 U2OS 48 5175 OutOfFocus -0.07554396455556531 7.01838955841942e-13 BR00117023 CDK7 shuffled orf K06 U2OS 48 5015 OutOfFocus -0.0719818376068376 2.946542058187715e-11 BR00117023 AKT1 shuffled orf J16 U2OS 48 4800 OutOfFocus -0.07386232482491963 4.97125823623034e-11 BR00117023 LYN shuffled orf C20 U2OS 48 4450 OutOfFocus -0.071765161694201 1.056253769007991e-10 BR00117023 CLK1 shuffled orf D08 U2OS 48 4580 OutOfFocus -0.06403857537676126 1.686256136262204e-10 BR00117023 ADH1C shuffled orf O04 U2OS 48 5640 OutOfFocus -0.07236975519869447 2.417751251619087e-10 BR00117022 PRKCE shuffled orf L14 U2OS 48 4335 OutOfFocus -0.06855941114616193 3.870731059830754e-10 BR00117022 LYN shuffled orf C20 U2OS 48 4755 OutOfFocus -0.05961688623391876 4.346150601820972e-10 BR00117022 CDC25A shuffled orf M04 U2OS 48 6235 OutOfFocus -0.08201892744479496 2.4827600442567915e-14 BR00117022 LYN shuffled orf C20 U2OS 48 4755 Polylobed -0.09848870497993044 6.856123239686876e-14 BR00117022 HSD11B1 shuffled orf C02 U2OS 48 3175 Polylobed -0.08467993899996999 1.092356544147926e-12 BR00117022 PTK2B shuffled orf N19 U2OS 48 3915 Polylobed -0.08774843390011235 1.3472188708181356e-12 BR00117022 ABL1 shuffled orf C01 U2OS 48 3625 Polylobed -0.08809094352316099 8.309964968143747e-12 BR00117022 PTK2B shuffled orf J18 U2OS 48 3365 Polylobed -0.06661910602478759 1.0559843469002604e-10 BR00117023 SIRT2 shuffled orf G02 U2OS 48 5320 Polylobed -0.06482038056506141 1.7269925432546846e-10 BR00117023 RPL23A shuffled orf I07 U2OS 48 5500 Polylobed -0.06462118161737813 2.091926168343273e-10 BR00117022 RPL23A shuffled orf G16 U2OS 48 5485 Polylobed -0.08103186646433991 7.869888418370672e-10 BR00117023 PTK2B shuffled orf J18 U2OS 48 3295 Polylobed -0.07483331948144152 1.2541775000165258e-09 BR00117023 PTK2B shuffled orf N19 U2OS 48 3770 Polylobed -0.16018571057225292 1.1871433496850223e-56 BR00117023 CDK7 shuffled orf K06 U2OS 48 5015 Prometaphase -0.15733629434211788 4.816645354240121e-56 BR00117023 GRIN2A shuffled orf A05 U2OS 48 5145 Prometaphase -0.14966999219518817 1.5445582164068325e-55 BR00117023 ADH1C shuffled orf O04 U2OS 48 5640 Prometaphase -0.1517578125 7.897690520356824e-52 BR00117023 TUBB3 shuffled orf K05 U2OS 48 5120 Prometaphase -0.1478847522850753 5.658918298016399e-47 BR00117023 TUBB3 shuffled orf G06 U2OS 48 4880 Prometaphase -0.17905918057663125 1.5091331545964416e-46 BR00117023 PTK2B shuffled orf J18 U2OS 48 3295 Prometaphase -0.14461942900777797 4.353524544410071e-44 BR00117023 SLC7A11 shuffled orf A03 U2OS 48 4780 Prometaphase -0.14334173391691243 2.5930441916296016e-41 BR00117023 KCNN4 shuffled orf A06 U2OS 48 4565 Prometaphase -0.14002824098977945 1.2882459555655244e-36 BR00117023 TUBB4B shuffled orf E04 U2OS 48 4225 Prometaphase -0.10770525569754823 2.0600198009707324e-28 BR00117023 DHH shuffled orf G05 U2OS 48 5540 Prometaphase -0.32774109621700775 6.699721352493482e-264 BR00117023 DHH shuffled orf G05 U2OS 48 5540 SmallIrregular -0.2609375 1.409868074838682e-153 BR00117023 TUBB3 shuffled orf K05 U2OS 48 5120 SmallIrregular -0.2443014705882353 7.445738908691608e-143 BR00117023 CDC25A shuffled orf M04 U2OS 48 5440 SmallIrregular -0.2400172624991409 3.1229212595045764e-126 BR00117023 HRH4 shuffled orf O06 U2OS 48 4975 SmallIrregular -0.2341602760042235 4.133652569233041e-121 BR00117023 CDK7 shuffled orf K06 U2OS 48 5015 SmallIrregular -0.22771280407569702 2.054111418612712e-117 BR00117023 GRIN2A shuffled orf A05 U2OS 48 5145 SmallIrregular -0.24260444579856802 3.968970165091482e-116 BR00117023 GABRB2 shuffled orf C06 U2OS 48 4475 SmallIrregular -0.2163177123983395 5.295524175098464e-116 BR00117023 ADH1C shuffled orf O04 U2OS 48 5640 SmallIrregular -0.2245225015278608 3.268011773709442e-108 BR00117023 TUBB3 shuffled orf G06 U2OS 48 4880 SmallIrregular -0.22395687156702307 9.714078684773603e-101 BR00117023 KCNN4 shuffled orf A06 U2OS 48 4565 SmallIrregular -0.10228990860920197 4.213715992849677e-20 BR00118040 CHRM3 shuffled orf A11 U2OS 96 4314 ADCCM -0.12394957983193278 1.5821794572639753e-19 BR00118040 CDK9 shuffled orf H11 U2OS 96 2856 ADCCM -0.09789525208027411 1.8608274166592435e-17 BR00118039 LYN shuffled orf M05 U2OS 96 4086 ADCCM -0.09428569258780399 2.6260326150578705e-17 BR00118040 VEGFA shuffled orf P18 U2OS 96 4356 ADCCM -0.10468739727828545 6.319396434094486e-17 BR00118040 PTGIS shuffled orf H13 U2OS 96 3444 ADCCM -0.09983952444286258 6.320999660199227e-17 BR00118040 KRAS shuffled orf F08 U2OS 96 3798 ADCCM -0.10185458223841376 1.161053815559285e-16 BR00118040 SSTR2 shuffled orf D02 U2OS 96 3588 ADCCM -0.08903431830835006 9.421852908079242e-15 BR00118040 RET shuffled orf E03 U2OS 96 4140 ADCCM -0.0820100923201188 2.0657298716238794e-14 BR00118039 CHRM3 shuffled orf A10 U2OS 96 4776 ADCCM -0.2380819180819181 3.864890480387122e-14 BR00118039 CSF1R shuffled orf D14 U2OS 96 546 ADCCM -0.18591139556146621 1.6855433918654507e-48 BR00118040 LYN shuffled orf C20 U2OS 96 3180 Anaphase -0.15376385545641927 1.6902843969557408e-42 BR00118039 LYN shuffled orf C20 U2OS 96 4080 Anaphase -0.14855604503181596 9.969735144752183e-40 BR00118039 LYN shuffled orf M05 U2OS 96 4086 Anaphase -0.11164646046845869 2.2296367919528543e-29 BR00118040 HSP90AB1 shuffled orf P01 U2OS 96 5334 Anaphase -0.16356778065742567 1.0517730139369085e-28 BR00118040 LYN shuffled orf M05 U2OS 96 2412 Anaphase -0.08306868637643491 2.453363525333351e-22 BR00118040 MAPK14 shuffled orf G22 U2OS 96 7296 Anaphase -0.5198476343223737 8.541708207393781e-22 BR00118040 GRIN2A shuffled orf A05 U2OS 96 174 Anaphase -0.11000795326164363 2.909684572843672e-20 BR00118039 KRAS shuffled orf F08 U2OS 96 3762 Anaphase -0.10727212606412863 2.5211653136511275e-19 BR00118040 SLCO2B1 shuffled orf A02 U2OS 96 3762 Anaphase -0.08392379009489809 3.3958398997838423e-18 BR00118040 CCR1 shuffled orf F24 U2OS 96 5796 Anaphase -0.1898048152446617 7.178788804437805e-48 BR00118039 DYRK1B shuffled orf G13 U2OS 96 3012 Apoptosis -0.7333600641539695 1.624559129640967e-45 BR00118040 GRIN2A shuffled orf A05 U2OS 96 174 Apoptosis -0.15128388601281947 9.68220937126356e-34 BR00118040 DYRK1B shuffled orf G13 U2OS 96 3336 Apoptosis -0.11483704974271013 6.221631960833051e-24 BR00118039 LYN shuffled orf C20 U2OS 96 4080 Apoptosis -0.11016364740549714 1.1647967921280547e-23 BR00118040 SCNN1G shuffled orf A04 U2OS 96 4386 Apoptosis -0.16463355853186362 1.469038942629056e-23 BR00118039 DYRK1B shuffled orf M12 U2OS 96 1950 Apoptosis -0.08084256111138027 1.751404277117163e-17 BR00118039 DNMT3A shuffled orf F04 U2OS 96 5982 Apoptosis -0.08636977058029689 7.601280921093614e-15 BR00118040 CDC25A shuffled orf I19 U2OS 96 4446 Apoptosis -0.06924302205007295 3.30105283271078e-14 BR00118040 MAPK14 shuffled orf G15 U2OS 96 6606 Apoptosis -0.07855571078126439 6.242413245239579e-14 BR00118039 F10 shuffled orf C09 U2OS 96 5028 Apoptosis -0.14913063966477963 5.75585955126705e-37 BR00118040 SLCO2B1 shuffled orf A02 U2OS 96 3762 Binuclear -0.12809656626203672 1.0026092683971787e-29 BR00118039 P3H1 shuffled orf P24 U2OS 96 4092 Binuclear -0.12715034124471586 3.1287658324947767e-27 BR00118040 KRAS shuffled orf F08 U2OS 96 3798 Binuclear -0.13112910005631093 4.544636034495481e-23 BR00118039 DYRK1B shuffled orf G13 U2OS 96 3012 Binuclear -0.09573440837914732 1.5038667083936898e-22 BR00118039 SSTR2 shuffled orf J01 U2OS 96 5532 Binuclear -0.0854126763549828 2.1337492737348095e-22 BR00118039 KCNH7 shuffled orf A22 U2OS 96 6924 Binuclear -0.16450462137181773 2.608512828680066e-21 BR00118039 KCNMA1 shuffled orf G01 U2OS 96 1764 Binuclear -0.10703174619472505 1.2870779268020457e-20 BR00118040 SSTR2 shuffled orf J01 U2OS 96 4044 Binuclear -0.10438765801277694 2.2163252704793894e-20 BR00118040 CDK4 shuffled orf P20 U2OS 96 4200 Binuclear -0.09823120434286868 8.079900368364154e-20 BR00118040 HIF1A shuffled orf A12 U2OS 96 4614 Binuclear -0.09022117237306619 2.768758704412671e-12 BR00118040 DYRK1B shuffled orf G13 U2OS 96 3336 Elongated -0.07202380952380952 8.666584644838098e-12 BR00118040 F10 shuffled orf C09 U2OS 96 5040 Elongated -0.060521192596664296 1.4106588716632454e-11 BR00118039 PIK3CG shuffled orf G18 U2OS 96 6996 Elongated -0.09270462147881002 2.860719921387883e-11 BR00118040 AGER shuffled orf H09 U2OS 96 2892 Elongated -0.0727832392231254 3.6183285978951596e-11 BR00118039 PAK1 shuffled orf L09 U2OS 96 4656 Elongated -0.07804232804232804 1.9662701333749793e-10 BR00118040 AKR1B1 shuffled orf L10 U2OS 96 3780 Elongated -0.06388358557873841 1.9855562768638377e-10 BR00118039 PTPN2 shuffled orf O15 U2OS 96 5628 Elongated -0.09197087498457361 2.2678630766751603e-10 BR00118040 DYRK1B shuffled orf M12 U2OS 96 2700 Elongated -0.07505599551742498 2.3474280633149546e-10 BR00118040 SSTR2 shuffled orf J01 U2OS 96 4044 Elongated -0.06911037325769306 3.313113061516104e-10 BR00118040 KCNH7 shuffled orf A22 U2OS 96 4692 Elongated -0.20388995096001994 2.3050125695670918e-58 BR00118040 LYN shuffled orf C20 U2OS 96 3180 Grape -0.1471600818715136 5.555212526353934e-39 BR00118039 LYN shuffled orf C20 U2OS 96 4080 Grape -0.1277533039647577 1.8340438469751473e-29 BR00118039 LYN shuffled orf M05 U2OS 96 4086 Grape -0.1071133810987644 1.1413731117811143e-21 BR00118040 NTRK1 shuffled orf P02 U2OS 96 4248 Grape -0.1369746790292219 3.6409422542756947e-20 BR00118040 LYN shuffled orf M05 U2OS 96 2412 Grape -0.08052441676465383 5.56967832825675e-20 BR00118039 KCNH7 shuffled orf A22 U2OS 96 6924 Grape -0.10076748550460772 4.5521175820570484e-17 BR00118039 KRAS shuffled orf F08 U2OS 96 3762 Grape -0.08971025923345538 5.069847152069769e-16 BR00118039 LCK shuffled orf H01 U2OS 96 4452 Grape -0.06911086864962668 6.505060430798306e-15 BR00118039 FPR1 shuffled orf D21 U2OS 96 6954 Grape -0.07675430501807938 4.29841985753718e-14 BR00118040 HSP90AB1 shuffled orf P01 U2OS 96 5334 Grape -0.1726008304706386 2.4324587631135526e-42 BR00118040 HDAC3 shuffled orf N21 U2OS 96 3222 Hole -0.11045072547161178 7.294784175300892e-26 BR00118040 NAMPT shuffled orf D13 U2OS 96 4776 Hole -0.18879053332842577 1.3312103079605603e-25 BR00118039 CDK9 shuffled orf H11 U2OS 96 1614 Hole -0.31190809190809193 4.7520943067404735e-24 BR00118039 CSF1R shuffled orf D14 U2OS 96 546 Hole -0.11951429220336783 3.2779304593471874e-21 BR00118040 IGF1R shuffled orf N16 U2OS 96 3330 Hole -0.10243719634696853 7.513065577393271e-21 BR00118039 CYP1A2 shuffled orf N12 U2OS 96 4458 Hole -0.13377064679872674 7.87440951530338e-20 BR00118039 IGF1R shuffled orf H05 U2OS 96 2478 Hole -0.12359943977591037 2.029083522899465e-19 BR00118040 CDK9 shuffled orf H11 U2OS 96 2856 Hole -0.10149259888163283 2.3105935601412147e-19 BR00118040 PPAT shuffled orf H14 U2OS 96 4212 Hole -0.11016467915956843 5.040937922918764e-19 BR00118040 JAK1 shuffled orf H17 U2OS 96 3522 Hole -0.16269399289929587 3.0679602862999037e-37 BR00118040 LYN shuffled orf C20 U2OS 96 3180 Interphase -0.12409299912074608 8.503575441825709e-28 BR00118039 LYN shuffled orf C20 U2OS 96 4080 Interphase -0.10303568607458663 3.9931368534771946e-25 BR00118040 HSP90AB1 shuffled orf P01 U2OS 96 5334 Interphase -0.11130814983610753 2.5410789646920674e-24 BR00118039 GAA shuffled orf N04 U2OS 96 4416 Interphase -0.11649786455155582 1.2844850564159977e-21 BR00118040 PAK1 shuffled orf L09 U2OS 96 3576 Interphase -0.09495521990707038 1.5802071372268164e-21 BR00118040 S1PR1 shuffled orf L01 U2OS 96 5370 Interphase -0.07997241756373838 9.883416143392335e-20 BR00118039 KCNH7 shuffled orf A22 U2OS 96 6924 Interphase -0.0909483203236971 8.437568797011857e-18 BR00118039 OPRM1 shuffled orf A09 U2OS 96 4812 Interphase -0.09180885420421801 1.4779071674037214e-17 BR00118039 CHRM3 shuffled orf A11 U2OS 96 4662 Interphase -0.08473476640938157 1.3765133463852008e-16 BR00118039 ABL1 shuffled orf M24 U2OS 96 5172 Interphase -0.19290551891213242 6.648367732222433e-29 BR00118039 PLD1 shuffled orf D10 U2OS 96 1746 Large -0.5244587008821171 3.172135312893593e-22 BR00118040 GRIN2A shuffled orf A05 U2OS 96 174 Large -0.09782080501267286 4.021621018840754e-20 BR00118039 EZH2 shuffled orf D04 U2OS 96 4722 Large -0.08676750093255413 6.989570803353263e-20 BR00118040 PAK4 shuffled orf G10 U2OS 96 5928 Large -0.08930899608865711 2.1892599812217274e-16 BR00118039 AKR1C1 shuffled orf I01 U2OS 96 4602 Large -0.09425802089032506 4.1033825438580394e-16 BR00118040 SSTR2 shuffled orf J01 U2OS 96 4044 Large -0.0866101048354362 5.441655388825334e-16 BR00118040 AGER shuffled orf H18 U2OS 96 4752 Large -0.10095961530277885 2.360406748910874e-15 BR00118040 SLC7A11 shuffled orf A03 U2OS 96 3360 Large -0.06987295825771325 1.866676996756257e-14 BR00118039 GABRB2 shuffled orf C19 U2OS 96 6612 Large -0.08416811425763836 5.442415568589067e-14 BR00118040 SCNN1G shuffled orf A04 U2OS 96 4386 Large -0.07154315046519089 2.7084679927184266e-14 BR00118040 KCTD16 shuffled orf K21 U2OS 96 6234 Metaphase -0.09790236546555332 2.9892431947541164e-12 BR00118040 BRD4 shuffled orf N17 U2OS 96 2826 Metaphase -0.07266009852216748 1.3229631932273676e-11 BR00118039 MAPK14 shuffled orf G15 U2OS 96 4872 Metaphase -0.07386121753937847 1.4493582627847806e-11 BR00118040 TNF shuffled orf C18 U2OS 96 4698 Metaphase -0.07334837623267028 3.104436387100737e-11 BR00118040 MMP2 shuffled orf F06 U2OS 96 4614 Metaphase -0.10802057636166708 3.213524426829479e-11 BR00118040 PTK2B shuffled orf J18 U2OS 96 2124 Metaphase -0.06508258082049635 4.92033976145674e-11 BR00118039 MAPK14 shuffled orf G22 U2OS 96 5748 Metaphase -0.06622510890522348 4.9623876029061964e-11 BR00118040 DHH shuffled orf G05 U2OS 96 5556 Metaphase -0.06143155596847574 7.169172899097285e-11 BR00118040 RET shuffled orf K10 U2OS 96 6342 Metaphase -0.06504065040650407 7.939413852960983e-11 BR00118040 S1PR1 shuffled orf P22 U2OS 96 5658 Metaphase -0.14366128242780224 3.5878587333688086e-37 BR00118039 LYN shuffled orf M05 U2OS 96 4086 MetaphaseAlignment -0.10158364862927316 3.522787830169865e-26 BR00118040 GRIN2A shuffled orf I24 U2OS 96 5730 MetaphaseAlignment -0.1261558560545649 1.8005775362434044e-24 BR00118040 NTRK1 shuffled orf D01 U2OS 96 3468 MetaphaseAlignment -0.08615073936551365 4.897238046200307e-24 BR00118040 P3H1 shuffled orf F23 U2OS 96 7308 MetaphaseAlignment -0.17405622862084674 9.176077510998376e-24 BR00118040 KRAS shuffled orf D17 U2OS 96 1764 MetaphaseAlignment -0.11244393095011554 1.3550023830366566e-23 BR00118040 CDK4 shuffled orf P20 U2OS 96 4200 MetaphaseAlignment -0.12743151620219195 5.513378589127659e-23 BR00118040 LYN shuffled orf C20 U2OS 96 3180 MetaphaseAlignment -0.10875052045401692 8.075984963515794e-22 BR00118040 ABL1 shuffled orf M24 U2OS 96 4152 MetaphaseAlignment -0.1082066102598844 2.79555117275942e-21 BR00118039 LYN shuffled orf C20 U2OS 96 4080 MetaphaseAlignment -0.08797282678261013 2.4447748309248686e-20 BR00118040 ADORA2A shuffled orf O18 U2OS 96 5904 MetaphaseAlignment -0.1395007342143906 4.5635576468541247e-35 BR00118039 LYN shuffled orf M05 U2OS 96 4086 OutOfFocus -0.11333114721017051 2.992233652803021e-23 BR00118039 LYN shuffled orf C20 U2OS 96 4080 OutOfFocus -0.10513541340408936 1.4607549218304045e-18 BR00118039 KRAS shuffled orf F08 U2OS 96 3762 OutOfFocus -0.11357445646365935 2.488371907331929e-18 BR00118040 LYN shuffled orf C20 U2OS 96 3180 OutOfFocus -0.09730836243179487 2.484736883499221e-17 BR00118039 P3H1 shuffled orf P24 U2OS 96 4092 OutOfFocus -0.1106796081447539 2.6824084552168248e-17 BR00118040 PRKCE shuffled orf J19 U2OS 96 3156 OutOfFocus -0.12248640758082772 3.136999458581876e-16 BR00118040 LYN shuffled orf M05 U2OS 96 2412 OutOfFocus -0.0927317690901724 1.5354104064720867e-14 BR00118040 SLCO2B1 shuffled orf A02 U2OS 96 3762 OutOfFocus -0.08465029577086802 6.788407612117438e-14 BR00118040 CHRM3 shuffled orf A11 U2OS 96 4314 OutOfFocus -0.06495898310591293 7.95481357295146e-14 BR00118040 MAPK14 shuffled orf G22 U2OS 96 7296 OutOfFocus -0.1276880837283522 6.75320069293194e-26 BR00118040 PAK1 shuffled orf L09 U2OS 96 3576 Polylobed -0.09272084561995425 2.678411180680202e-25 BR00118040 FLT3 shuffled orf E14 U2OS 96 6648 Polylobed -0.12864623532065972 2.2407596315443824e-23 BR00118040 LYN shuffled orf C20 U2OS 96 3180 Polylobed -0.1018432122934118 5.389417276535223e-22 BR00118040 NAMPT shuffled orf D13 U2OS 96 4776 Polylobed -0.10328313612831448 1.1202233793256966e-21 BR00118039 CHEK2 shuffled orf H06 U2OS 96 4566 Polylobed -0.13739430587394158 6.926855436932487e-21 BR00118039 IGF1R shuffled orf H05 U2OS 96 2478 Polylobed -0.09412368985431248 1.1280054628084205e-18 BR00118039 EZH2 shuffled orf D04 U2OS 96 4722 Polylobed -0.07325581395348837 1.766663510883481e-18 BR00118039 ERBB2 shuffled orf I20 U2OS 96 7740 Polylobed -0.09587586498804028 4.267682011214936e-18 BR00118039 GAA shuffled orf N04 U2OS 96 4416 Polylobed -0.08541781049167091 2.0891663962944652e-17 BR00118040 HSP90AB1 shuffled orf P01 U2OS 96 5334 Polylobed -0.09432502364974867 4.9829053068086495e-22 BR00118040 CDK2 shuffled orf J04 U2OS 96 5580 Prometaphase -0.10728285986135654 1.6842949918554694e-21 BR00118040 CDK4 shuffled orf P20 U2OS 96 4200 Prometaphase -0.101976819503315 3.4617451922870963e-16 BR00118040 NTRK1 shuffled orf D01 U2OS 96 3468 Prometaphase -0.08247444671888106 4.0524591746115577e-16 BR00118039 PLA2G1B shuffled orf E06 U2OS 96 5304 Prometaphase -0.07046657046657047 1.4752153071953464e-15 BR00118039 PIK3CG shuffled orf G18 U2OS 96 6996 Prometaphase -0.07619065856869002 1.6232781430082173e-15 BR00118039 TUBB3 shuffled orf G06 U2OS 96 5976 Prometaphase -0.07281724991162955 1.8260144997380879e-13 BR00118040 S1PR1 shuffled orf P22 U2OS 96 5658 Prometaphase -0.0706967213114754 3.8052674885501577e-13 BR00118039 IL1B shuffled orf G08 U2OS 96 5856 Prometaphase -0.07814403620387436 5.193167240098348e-13 BR00118039 CCR1 shuffled orf F24 U2OS 96 4728 Prometaphase -0.09170183326077305 1.1452594954960157e-12 BR00118040 DYRK1B shuffled orf G13 U2OS 96 3336 Prometaphase -0.16264649655057767 3.3487385133414975e-37 BR00118040 LYN shuffled orf C20 U2OS 96 3180 SmallIrregular -0.1309742421840091 6.354741776231698e-31 BR00118039 LYN shuffled orf C20 U2OS 96 4080 SmallIrregular -0.0998263888888889 2.1530622343997924e-25 BR00118039 SIRT2 shuffled orf G02 U2OS 96 5760 SmallIrregular -0.11878921989283044 1.4726135680747586e-23 BR00118039 KRAS shuffled orf F08 U2OS 96 3762 SmallIrregular -0.08281653746770026 1.664951397807809e-23 BR00118039 ERBB2 shuffled orf I20 U2OS 96 7740 SmallIrregular -0.08631820826548847 3.1192709947057664e-18 BR00118040 LCK shuffled orf B18 U2OS 96 5484 SmallIrregular -0.15024670481132293 8.392917568978669e-18 BR00118039 KCNMA1 shuffled orf G01 U2OS 96 1764 SmallIrregular -0.10188511948248194 1.2578455120959127e-17 BR00118040 KRAS shuffled orf F08 U2OS 96 3798 SmallIrregular -0.07088387120063533 2.2118455923136425e-16 BR00118040 MAPK14 shuffled orf G22 U2OS 96 7296 SmallIrregular -0.1356959424756035 4.2822489382952703e-16 BR00118039 DYRK1B shuffled orf M12 U2OS 96 1950 SmallIrregular +0.10663352794965811 2.9275661606765706e-29 BR00118039 TUBB final orf E19 U2OS 96 5814 SmallIrregular +0.10787353268709698 9.485376648599596e-27 BR00118040 GHSR final orf A17 U2OS 96 5196 SmallIrregular +0.13097921902142756 1.9510607882308572e-25 BR00118040 DYRK1B final orf G13 U2OS 96 3336 SmallIrregular +0.09312320916905444 4.06923644860294e-24 BR00118040 TGM2 final orf B07 U2OS 96 6282 SmallIrregular +0.11396389590921026 2.4890070190384394e-23 BR00118040 SSTR2 final orf J01 U2OS 96 4044 SmallIrregular +0.08010335917312661 5.134108553741582e-22 BR00118039 ERBB2 final orf I20 U2OS 96 7740 SmallIrregular +0.09054960084439621 1.866800195513918e-21 BR00118040 CSK final orf P05 U2OS 96 5892 SmallIrregular +0.08329291856231189 4.251613773741404e-21 BR00118040 GLRA3 final orf K04 U2OS 96 6840 SmallIrregular +0.12526007449961268 4.517717941610794e-21 BR00118039 DYRK1B final orf G13 U2OS 96 3012 SmallIrregular +0.6141141141141141 9.328957113706411e-20 BR00118039 SCNN1G final orf A04 U2OS 96 108 SmallIrregular +0.08837044892188052 1.2254024289558383e-19 BR00118040 ITGB2 final orf B12 U2OS 96 5658 SmallIrregular +0.10236295148348337 2.5397869004476394e-19 BR00118040 CCR1 final orf P17 U2OS 96 4134 SmallIrregular +0.08663194444444444 3.1977703092890185e-19 BR00118039 SIRT2 final orf G02 U2OS 96 5760 SmallIrregular +0.0856269113149847 3.445566367301052e-19 BR00118040 CYP3A4 final orf K22 U2OS 96 5886 SmallIrregular +0.11669829222011385 3.629786831081267e-19 BR00118040 ABL1 final orf C01 U2OS 96 3162 SmallIrregular +0.09574125761909878 7.258594451258892e-19 BR00118040 HIF1A final orf A12 U2OS 96 4614 SmallIrregular +0.08304017143777329 3.724336728683301e-18 BR00118040 PIK3CG final orf I03 U2OS 96 5904 SmallIrregular +0.07776135904577637 3.968376426990014e-18 BR00118040 USP1 final orf G11 U2OS 96 6720 SmallIrregular +0.08834995917464983 9.932223364492574e-18 BR00118040 KDR final orf A21 U2OS 96 5082 SmallIrregular +0.08452518962345039 1.1286610011727512e-17 BR00118039 SSTR2 final orf J01 U2OS 96 5532 SmallIrregular +0.0863431151241535 1.1734577970385544e-17 BR00118040 CACNB4 final orf A18 U2OS 96 5316 SmallIrregular +0.10986241781990477 1.866677137160891e-17 BR00118040 CCND1 final orf P16 U2OS 96 3228 SmallIrregular +0.07695193507780192 1.9347508146027696e-17 BR00118040 MAPK14 final orf G15 U2OS 96 6606 SmallIrregular +0.08370767521615224 2.0279073248795123e-17 BR00118040 HCK final orf O20 U2OS 96 5562 SmallIrregular +0.0949179473846484 2.189197343295841e-17 BR00118040 CHRM3 final orf A11 U2OS 96 4314 SmallIrregular +0.14236816612434486 2.6956354372001424e-17 BR00118040 CLK1 final orf J17 U2OS 96 1902 SmallIrregular +0.11898226994117406 4.3847400223413765e-17 BR00118040 DYRK1B final orf M12 U2OS 96 2700 SmallIrregular +0.08240295617479194 1.1120832221034555e-16 BR00118040 USP1 final orf E12 U2OS 96 5502 SmallIrregular +0.09331288359697884 1.1430029089791213e-16 BR00118040 HTR2C final orf M06 U2OS 96 4272 SmallIrregular +0.10164679159568427 2.966034984650946e-16 BR00118040 JAK1 final orf H17 U2OS 96 3522 SmallIrregular +0.4470729751403368 3.2737491380748004e-16 BR00118040 GRIN2A final orf A05 U2OS 96 174 SmallIrregular +0.07348082526999798 4.507571885175466e-16 BR00118040 FLT3 final orf E14 U2OS 96 6648 SmallIrregular +0.08089774259707995 8.274835290692734e-16 BR00118039 HTR2C final orf G21 U2OS 96 5394 SmallIrregular +0.07840709112212478 9.101491980210783e-16 BR00118040 KCNQ2 final orf K02 U2OS 96 5730 SmallIrregular +0.08343333515827416 2.112829323690377e-15 BR00118040 EDNRB final orf M08 U2OS 96 4932 SmallIrregular +0.07758491059461933 2.722078094234218e-15 BR00118040 TGFBR1 final orf I23 U2OS 96 5670 SmallIrregular +0.08413199851363824 6.939024507595534e-15 BR00118040 KCNH7 final orf A22 U2OS 96 4692 SmallIrregular +0.07724201653352787 7.0869395537428926e-15 BR00118040 DHH final orf G05 U2OS 96 5556 SmallIrregular +0.08940072717828854 1.2008048965509013e-14 BR00118040 FOXM1 final orf P15 U2OS 96 4080 SmallIrregular +0.0927508214753405 1.5194858192068886e-14 BR00118040 SLCO2B1 final orf A02 U2OS 96 3762 SmallIrregular +0.08865214080642819 3.3689151348286546e-14 BR00118039 DCK final orf L18 U2OS 96 4026 SmallIrregular +0.06511330409356725 6.865844000218969e-14 BR00118040 MAPK14 final orf G22 U2OS 96 7296 SmallIrregular +0.06913233458177279 9.793001653508083e-14 BR00118040 AVPR1A final orf D07 U2OS 96 6408 SmallIrregular +0.07027532515596913 1.0554868477762761e-13 BR00118040 RPL23A final orf G16 U2OS 96 6174 SmallIrregular +0.0691613937208476 1.4326223941946172e-13 BR00118039 FFAR4 final orf C17 U2OS 96 6300 SmallIrregular +0.06415576655682322 1.6201277524360077e-13 BR00118040 P3H1 final orf F23 U2OS 96 7308 SmallIrregular +0.07167143282150294 2.2137153760085164e-13 BR00118040 CCR1 final orf F24 U2OS 96 5796 SmallIrregular +0.09244952158912055 2.2432171351876022e-13 BR00118040 NTRK1 final orf D01 U2OS 96 3468 SmallIrregular +0.07700980075080795 2.4546127388127364e-13 BR00118040 ALK final orf H12 U2OS 96 5004 SmallIrregular +0.0851275607702498 2.5125109046783057e-13 BR00118040 AURKB final orf H10 U2OS 96 4086 SmallIrregular +0.07093220586173245 3.1290932039113905e-13 BR00118039 KCNN1 final orf O10 U2OS 96 5844 SmallIrregular +0.06865001161886533 3.247628067283604e-13 BR00118040 HTR2C final orf G21 U2OS 96 6228 SmallIrregular +0.07086748633879782 3.302227024826975e-13 BR00118039 IL1B final orf G08 U2OS 96 5856 SmallIrregular +0.07146371966600205 3.4804658976411684e-13 BR00118039 ATM final orf C04 U2OS 96 5736 SmallIrregular +0.07189481882579832 8.990629917644312e-13 BR00118040 LCK final orf B18 U2OS 96 5484 SmallIrregular +0.0776442456852612 1.1679094172215135e-12 BR00118039 PAK1 final orf L09 U2OS 96 4656 SmallIrregular +0.06922243804435037 1.675261253316689e-12 BR00118040 EDNRB final orf K11 U2OS 96 5784 SmallIrregular +0.1252673600654791 1.6958412381871763e-12 BR00118040 KRAS final orf D17 U2OS 96 1764 SmallIrregular +0.07736495656894679 1.951364475251917e-12 BR00118040 TUBB3 final orf K05 U2OS 96 4608 SmallIrregular +0.0697098372257608 2.313218523905834e-12 BR00118040 HRH4 final orf O06 U2OS 96 5652 SmallIrregular +0.08956422089901148 2.4904807459937536e-12 BR00118040 LPAR1 final orf B20 U2OS 96 3396 SmallIrregular +0.06855886292949111 2.7397772485320528e-12 BR00118040 HTR3A final orf H24 U2OS 96 5790 SmallIrregular +0.07237247837356468 3.2783816768918188e-12 BR00118039 ABL1 final orf M24 U2OS 96 5172 SmallIrregular +0.07794589637780834 6.04184574372162e-12 BR00118040 CYP1A2 final orf N12 U2OS 96 4362 SmallIrregular +0.07656458055925433 6.595970529886969e-12 BR00118040 MAPK8 final orf I14 U2OS 96 4506 SmallIrregular +0.07560665757014742 1.070414331131919e-11 BR00118040 SIRT2 final orf G02 U2OS 96 4518 SmallIrregular +0.056852409638554216 1.290679179957578e-11 BR00118039 HIF1A final orf C23 U2OS 96 7968 SmallIrregular +0.05998266146727646 2.924063204450153e-11 BR00118039 KCNH7 final orf A22 U2OS 96 6924 SmallIrregular +0.09278711484593838 4.06297797348712e-11 BR00118040 CDK9 final orf H11 U2OS 96 2856 SmallIrregular +0.07050168613954087 4.6465611138315625e-11 BR00118040 CSK final orf B04 U2OS 96 4902 SmallIrregular +0.07212159310339188 6.849417320225035e-11 BR00118040 MMP2 final orf F06 U2OS 96 4614 SmallIrregular +0.06191851138915624 8.228986107142889e-11 BR00118040 P3H1 final orf P24 U2OS 96 6234 SmallIrregular +0.06644958558955408 9.974330765167239e-11 BR00118039 CACNA2D3 final orf P19 U2OS 96 5364 SmallIrregular +0.0741672875969915 1.0524003424301389e-10 BR00118039 BTK final orf P10 U2OS 96 4290 SmallIrregular +0.06553592886325403 1.1215878731192242e-10 BR00118040 HSP90AA1 final orf C14 U2OS 96 5472 SmallIrregular +0.07577972709551657 1.1408504763737914e-10 BR00118039 CACNB4 final orf M01 U2OS 96 4104 SmallIrregular +0.06462883023516357 1.1575146715160821e-10 BR00118039 ANXA1 final orf D23 U2OS 96 5628 SmallIrregular +0.09715703922635367 1.1679173429636834e-10 BR00118039 IGF1R final orf H05 U2OS 96 2478 SmallIrregular +0.07127335940895263 1.3827157023145074e-10 BR00118039 AKR1C1 final orf I01 U2OS 96 4602 SmallIrregular +0.07691689273556639 1.5178378167682117e-10 BR00118040 SLC29A1 final orf N03 U2OS 96 3930 SmallIrregular +0.07593326670658096 2.5691228024977315e-10 BR00118040 CCND1 final orf B11 U2OS 96 3942 SmallIrregular +0.06814449917898194 2.9441175856348444e-10 BR00118039 MAPK14 final orf G15 U2OS 96 4872 SmallIrregular +0.059876143609250844 6.910902658591589e-10 BR00118040 S1PR4 final orf K18 U2OS 96 6054 SmallIrregular +0.0902621722846442 6.960627083735302e-10 BR00118040 GAA final orf N15 U2OS 96 2670 SmallIrregular +0.07221081903796425 7.038653674486121e-10 BR00118040 ABL1 final orf M24 U2OS 96 4152 SmallIrregular +0.0713376653324434 8.941729974936063e-10 BR00118040 PPAT final orf H14 U2OS 96 4212 SmallIrregular +0.05800780182671441 1.0745752021656595e-09 BR00118039 HPGDS final orf O21 U2OS 96 6330 SmallIrregular +0.06497046818727491 1.3032436084521876e-09 BR00118040 BRD4 final orf F14 U2OS 96 4998 SmallIrregular +0.08069387094162415 1.4405228917940346e-09 BR00118040 HDAC3 final orf N21 U2OS 96 3222 SmallIrregular +0.06293790207872171 1.952110445630091e-09 BR00118040 EZH2 final orf D04 U2OS 96 5226 SmallIrregular diff --git a/3.evaluate_model/jump_phenotype_profiles/jump_phenotype_profiles.tsv.gz b/3.evaluate_model/jump_phenotype_profiles/jump_phenotype_profiles.tsv.gz index 070a011..a0e68bc 100644 Binary files a/3.evaluate_model/jump_phenotype_profiles/jump_phenotype_profiles.tsv.gz and b/3.evaluate_model/jump_phenotype_profiles/jump_phenotype_profiles.tsv.gz differ diff --git a/3.evaluate_model/jump_phenotype_profiles/jump_phenotype_profiles_shuffled.tsv.gz b/3.evaluate_model/jump_phenotype_profiles/jump_phenotype_profiles_shuffled.tsv.gz index 8713e58..b438afa 100644 Binary files a/3.evaluate_model/jump_phenotype_profiles/jump_phenotype_profiles_shuffled.tsv.gz and b/3.evaluate_model/jump_phenotype_profiles/jump_phenotype_profiles_shuffled.tsv.gz differ diff --git a/3.evaluate_model/process_jump_phenotype_profiles.ipynb b/3.evaluate_model/process_jump_phenotype_profiles.ipynb index 5fbe817..6be8375 100644 --- a/3.evaluate_model/process_jump_phenotype_profiles.ipynb +++ b/3.evaluate_model/process_jump_phenotype_profiles.ipynb @@ -32,9 +32,7 @@ "source": [ "import pathlib\n", "from typing import List\n", - "import pandas as pd\n", - "\n", - "import umap" + "import pandas as pd" ] }, { @@ -54,7 +52,7 @@ "jump_sc_pred_file = f\"{url}/{commit}/{file}\"\n", "\n", "# Set constants\n", - "n_top_results_to_explore = 10" + "n_top_results_to_explore = 100" ] }, { @@ -436,7 +434,7 @@ "name": "stdout", "output_type": "stream", "text": [ - "(3600, 11)\n" + "(18000, 11)\n" ] }, { @@ -580,6 +578,7 @@ "# Focus on the top results for downstream interpretation\n", "jump_focused_top_results_df = (\n", " jump_pred_df\n", + " .query(\"Metadata_model_type == 'final'\")\n", " .groupby([\"Metadata_model_type\", \"treatment_type\", \"Cell_type\", \"Time\", \"phenotype\"])\n", " .apply(lambda x: x.nsmallest(n_top_results_to_explore, \"p_value\"))\n", " .reset_index(drop=True)\n", diff --git a/3.evaluate_model/scripts/nbconverted/process_jump_phenotype_profiles.py b/3.evaluate_model/scripts/nbconverted/process_jump_phenotype_profiles.py index 58b3a39..65eb32d 100644 --- a/3.evaluate_model/scripts/nbconverted/process_jump_phenotype_profiles.py +++ b/3.evaluate_model/scripts/nbconverted/process_jump_phenotype_profiles.py @@ -25,8 +25,6 @@ from typing import List import pandas as pd -import umap - # In[2]: @@ -41,7 +39,7 @@ jump_sc_pred_file = f"{url}/{commit}/{file}" # Set constants -n_top_results_to_explore = 10 +n_top_results_to_explore = 100 # In[3]: @@ -125,6 +123,7 @@ # Focus on the top results for downstream interpretation jump_focused_top_results_df = ( jump_pred_df + .query("Metadata_model_type == 'final'") .groupby(["Metadata_model_type", "treatment_type", "Cell_type", "Time", "phenotype"]) .apply(lambda x: x.nsmallest(n_top_results_to_explore, "p_value")) .reset_index(drop=True)