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<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="utf-8" />
<title>SAVER - Single Amino acid Variant EvaluateR</title>
<link rel="stylesheet" href="css/csvtable.css" type="text/css" />
<link rel="stylesheet" href="css/headers.css" />
<style>
.hidden {
display:none;
}
.link{
font-size:"28px";
}
.link:hover{
color:"red";
}
</style>
<script type="text/javascript" src="js/jquery-1.4.2.min.js"></script>
<script type="text/javascript" src="js/jquery.tablesorter.dev.js"></script>
<script type="text/javascript" src="http://web.utk.edu/~oadebali/svg_library.js"></script>
<link rel="stylesheet" href="//code.jquery.com/ui/1.11.4/themes/smoothness/jquery-ui.css">
<script src="//code.jquery.com/jquery-1.10.2.js"></script>
<script src="//code.jquery.com/ui/1.11.4/jquery-ui.js"></script>
<script type="text/javascript" src="js/jquery.csvToTable_npc1.js"></script>
<script>
function getResult(switchButton){
$(".heads").show();
var aa0 = $("#aa0").val()
var aa1 = $("#minbeds").val()
var position = $("#amount").val()
var mutationString = aa0 + position + aa1;
if (switchButton==-1){
$(".rows").hide();
}
if (switchButton){
$("#" + mutationString).show();
if(aa0==aa1){$("#empty").show();}
$("#" + "aa" + (parseInt(position)-1).toString() + "_symbol").attr("stroke-width","4").attr("stroke",$("#" + "aa" + (parseInt(position)-1).toString() + "_symbol").attr("fill"))
}
else{
$("#" + mutationString).hide();
if(aa0==aa1){$("#empty").hide();}
$("#" + "aa" + (parseInt(position)-1).toString() + "_symbol").attr("stroke-width","0")
}
}
function openTree(){
window.open("treelign/treelign.html?f=" + $("#amount").val() + "&newick=NPC1-L1.sn.noGap.fa..phy_phyml_trec.noded.nwk.trueNPC1.distance.nwk.sorted&json=NPC1-L1.sn.TrueNPC1.fa.afa.distance.afa.json&first=gi|255652944&r=25");
}
$(function() {
var seq = "MTARGLALGLLLLLLCPAQVFSQSCVWYGECGIAYGDKRYNCEYSGPPKPLPKDGYDLVQELCPGFFFGNVSLCCDVRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNKDNGQAPFTITPVFSDFPVHGMEPMNNATKGCDESVDEVTAPCSCQDCSIVCGPKPQPPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAFSVNASDKGEASCCDPVSAAFEGCLRRLFTRWGSFCVRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHIYQPYPSGADVPFGPPLDIQILHQVLDLQIAIENITASYDNETVTLQDICLAPLSPYNTNCTILSVLNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAQAWEKEFINFVKNYKNPNLTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVRGAEDGTSVQASESCLFRFFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNKVDIGLDQSLSMPDDSYMVDYFKSISQYLHAGPPVYFVLEEGHDYTSSKGQNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVDNITDQFCNASVVDPACVRCRPLTPEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILLGHGTRVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGINGSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKSCATEERYKGTERERLLNF"
$( "#slider-range-max" ).slider({
range: "max",
min: 1,
max: 1278,
value: 1,
slide: function( event, ui ) {
getResult(0);
$( "#amount" ).val( ui.value );
$( "#aa0" ).val( seq[ui.value-1] );
getResult(1);
}
});
$( "#amount" ).val( $( "#slider-range-max" ).slider( "value" ) );
//$( "#aa0" ).val( $( "#slider-range-max" ).slider( "value" ) );
$( "#aa0" ).val( seq[0] );
var select = $( "#minbeds" );
var slider = $( "<div id='slider'></div>" ).insertAfter( select ).slider({
min: 1,
max: 20,
range: "min",
value: select[ 0 ].selectedIndex + 1,
slide: function( event, ui ) {
getResult(0);
select[ 0 ].selectedIndex = ui.value - 1;
getResult(1);
}
});
$( "#minbeds" ).change(function() {
getResult(-1);
slider.slider( "value", this.selectedIndex + 1 );
getResult(1);
});
//});
// $(function() {
// $.get('test.csv', function(data) {
// $('#CSVSource').html('<pre>' + data + '</pre>');
// });
$('#CSVTable').CSVToTable('S2.csv', { loadingImage: 'images/loading.gif', startLine: 0 });
// $.get('test.tsv', function(data) {
// $('#TSVSource').html('<pre>' + data + '</pre>');
// });
// $('#TSVTable').CSVToTable('test.tsv', { loadingText: 'Loading TSV Data...', loadingImage: 'images/loading.gif', startLine: 0, separator: "\t" });
// $('#CSVTable2').CSVToTable('test.csv', { loadingImage: 'images/loading.gif', startLine: 1, headers: ['Album Title', 'Artist Name', 'Price ($USD)'] }).bind("loadComplete",function() {
// $('#CSVTable2').find('TABLE').tablesorter();
// });;
});
</script>
</head>
<body>
<h2>SAVER predictions on NPC1 mutations for Niemann-Pick disease type C</h2>
<p>
<label for="amount" style="font-size:20px"><b>NPC1 protein position: </b></label>
<input type="text" id="amount" readonly style="border:0; font-size:24px; color:#000; font-weight:bold;">
<br>
<label for="aa0" style="font-size:20px"><b>Original amino-acid (AA0): </b></label>
<input type="text" id="aa0" readonly style="border:0; font-size:24px; color:#000; font-weight:bold;">
<div id="slider-range-max" style="margin-top:-30px"></div>
</p>
<p>
<form id="reservation">
<label for="minbeds" style="font-family: 'Open Sans', sans-serif;font-size:20px"><b>Replacing amino-acid (AA1): </b></label>
<select style="border:0; font-size:24px; color:#000; font-weight:bold;" name="minbeds" id="minbeds">
<option>A</option>
<option>C</option>
<option>D</option>
<option>E</option>
<option>F</option>
<option>G</option>
<option>H</option>
<option>I</option>
<option>K</option>
<option>L</option>
<option>M</option>
<option>N</option>
<option>P</option>
<option>Q</option>
<option>R</option>
<option>S</option>
<option>T</option>
<option>V</option>
<option>W</option>
<option>Y</option>
</select>
</form>
<br>
</p>
<div id="CSVTable"></div>
<div>
<br>
<svg version='1.1' height='320.408pt' width='100%' viewBox='-21.3033 55.56 491.682 220.408' xmlns='http://www.w3.org/2000/svg' xmlns:xlink='http://www.w3.org/1999/xlink'>
<title>generated using Protter</title>
<defs>
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<use id='aa13_letter' fill='#000000' x='-1.82666' xlink:href='#g276' y='78.3727'><title>Leu14: circ00FF00FFFFFF</title></use>
<circle id='aa14_symbol' r='1.6' cx='-1.2130802' cy='74.3486' fill='#55ff00' stroke='#ffffff' stroke-width='0.3'><title>Leu15: circ55FF00FFFFFF</title></circle>
<use id='aa14_letter' fill='#000000' x='-1.82666' xlink:href='#g276' y='75.1658'><title>Leu15: circ55FF00FFFFFF</title></use>
<circle id='aa15_symbol' r='1.6' cx='-1.2130802' cy='71.1416' fill='#55ff00' stroke='#ffffff' stroke-width='0.3'><title>Cys16: circ55FF00FFFFFF</title></circle>
<use id='aa15_letter' fill='#000000' x='-1.93462' xlink:href='#g267' y='71.9588'><title>Cys16: circ55FF00FFFFFF</title></use>
<circle id='aa16_symbol' r='1.6' cx='-1.2130802' cy='67.9347' fill='#55ff00' stroke='#ffffff' stroke-width='0.3'><title>Pro17: circ55FF00FFFFFF</title></circle>
<use id='aa16_letter' fill='#000000' x='-1.93622' xlink:href='#g280' y='68.7519'><title>Pro17: circ55FF00FFFFFF</title></use>
<circle id='aa17_symbol' r='1.6' cx='-0.5716901' cy='64.7278' fill='#55ff00' stroke='#ffffff' stroke-width='0.3'><title>Ala18: circ55FF00FFFFFF</title></circle>
<use id='aa17_letter' fill='#000000' x='-1.32706' xlink:href='#g265' y='65.545'><title>Ala18: circ55FF00FFFFFF</title></use>
<circle id='aa18_symbol' r='1.6' cx='1.3524718' cy='62.1622' fill='#55ff00' stroke='#ffffff' stroke-width='0.3'><title>Gln19: circ55FF00FFFFFF</title></circle>
<use id='aa18_letter' fill='#000000' x='0.526215' xlink:href='#g281' y='62.9794'><title>Gln19: circ55FF00FFFFFF</title></use>
<circle id='aa19_symbol' r='1.6' cx='4.55941' cy='62.1622' fill='#ff6600' stroke='#ffffff' stroke-width='0.3'><title>Val20: circFF6600FFFFFF</title></circle>
<use id='aa19_letter' fill='#000000' x='3.80405' xlink:href='#g286' y='62.9794'><title>Val20: circFF6600FFFFFF</title></use>
<text x='4.55941' y='64.1622' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>20</text><circle id='aa20_symbol' r='1.6' cx='6.48358' cy='64.7278' fill='#00ff00' stroke='#ffffff' stroke-width='0.3'><title>Phe21: circ00FF00FFFFFF</title></circle>
<use id='aa20_letter' fill='#000000' x='5.83937' xlink:href='#g270' y='65.545'><title>Phe21: circ00FF00FFFFFF</title></use>
<circle id='aa21_symbol' r='1.6' cx='7.12496' cy='67.9347' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Ser22: circAAFF00FFFFFF</title></circle>
<use id='aa21_letter' fill='#000000' x='6.49527' xlink:href='#g283' y='68.7519'><title>Ser22: circAAFF00FFFFFF</title></use>
<circle id='aa22_symbol' r='1.6' cx='7.12496' cy='71.1416' fill='#ffcc00' stroke='#ffffff' stroke-width='0.3'><title>Gln23: circFFCC00FFFFFF</title></circle>
<use id='aa22_letter' fill='#000000' x='6.29871' xlink:href='#g281' y='71.9588'><title>Gln23: circFFCC00FFFFFF</title></use>
<circle id='aa23_symbol' r='1.6' cx='7.12496' cy='74.3486' fill='#00ff00' stroke='#ffffff' stroke-width='0.3'><title>Ser24: circ00FF00FFFFFF</title></circle>
<use id='aa23_letter' fill='#000000' x='6.49527' xlink:href='#g283' y='75.1658'><title>Ser24: circ00FF00FFFFFF</title></use>
<circle id='aa24_symbol' r='1.6' cx='7.12496' cy='77.555504' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Cys25: circE00000FFFFFF</title></circle>
<use id='aa24_letter' fill='#000000' x='6.40343' xlink:href='#g267' y='78.3727'><title>Cys25: circE00000FFFFFF</title></use>
<circle id='aa25_symbol' r='1.6' cx='7.12496' cy='80.762505' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Val26: circFF2200FFFFFF</title></circle>
<use id='aa25_letter' fill='#000000' x='6.3696' xlink:href='#g286' y='81.5797'><title>Val26: circFF2200FFFFFF</title></use>
<rect id='aa26_symbol' height='2.5' width='2.5' x='5.87496' y='82.7194' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Trp27: boxE00000000000</title></rect>
<use id='aa26_letter' fill='#000000' x='6.06349' xlink:href='#g287' y='84.7866'><title>Trp27: boxE00000000000</title></use>
<rect id='aa27_symbol' height='2.5' width='2.5' x='5.87496' y='85.9263' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Tyr28: boxFF2200000000</title></rect>
<use id='aa27_letter' fill='#000000' x='6.3696' xlink:href='#g289' y='87.9935'><title>Tyr28: boxFF2200000000</title></use>
<rect id='aa28_symbol' height='2.5' width='2.5' x='5.87496' y='89.1333' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Gly29: boxE00000000000</title></rect>
<use id='aa28_letter' fill='#000000' x='6.37282' xlink:href='#g271' y='91.2005'><title>Gly29: boxE00000000000</title></use>
<rect id='aa29_symbol' height='2.5' width='2.5' x='5.87496' y='92.3402' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Glu30: boxFF2200000000</title></rect>
<use id='aa29_letter' fill='#000000' x='6.45015' xlink:href='#g269' y='94.4074'><title>Glu30: boxFF2200000000</title></use>
<text x='5.12496' y='93.5902' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>30</text><rect id='aa30_symbol' height='2.5' width='2.5' x='5.87496' y='95.5472' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Cys31: boxE00000000000</title></rect>
<use id='aa30_letter' fill='#000000' x='6.40343' xlink:href='#g267' y='97.6144'><title>Cys31: boxE00000000000</title></use>
<rect id='aa31_symbol' height='2.5' width='2.5' x='5.87496' y='98.754' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Gly32: boxFF8800000000</title></rect>
<use id='aa31_letter' fill='#000000' x='6.37282' xlink:href='#g271' y='100.821'><title>Gly32: boxFF8800000000</title></use>
<rect id='aa32_symbol' height='2.5' width='2.5' x='5.87496' y='101.961' fill='#55ff00' stroke='#000000' stroke-width='0.3'><title>Ile33: box55FF00000000</title></rect>
<use id='aa32_letter' fill='#000000' x='6.77881' xlink:href='#g273' y='104.028'><title>Ile33: box55FF00000000</title></use>
<rect id='aa33_symbol' height='2.5' width='2.5' x='5.87496' y='105.168' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Ala34: boxFF4400000000</title></rect>
<use id='aa33_letter' fill='#000000' x='6.3696' xlink:href='#g265' y='107.235'><title>Ala34: boxFF4400000000</title></use>
<rect id='aa34_symbol' height='2.5' width='2.5' x='5.87496' y='108.375' fill='#ffaa00' stroke='#000000' stroke-width='0.3'><title>Tyr35: boxFFAA00000000</title></rect>
<use id='aa34_letter' fill='#000000' x='6.3696' xlink:href='#g289' y='110.442'><title>Tyr35: boxFFAA00000000</title></use>
<circle id='aa35_symbol' r='1.6' cx='7.12496' cy='112.832' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Gly36: circFF4400FFFFFF</title></circle>
<use id='aa35_letter' fill='#000000' x='6.37282' xlink:href='#g271' y='113.649'><title>Gly36: circFF4400FFFFFF</title></use>
<circle id='aa36_symbol' r='1.6' cx='7.12496' cy='116.039' fill='#ff6600' stroke='#ffffff' stroke-width='0.3'><title>Asp37: circFF6600FFFFFF</title></circle>
<use id='aa36_letter' fill='#000000' x='6.30998' xlink:href='#g268' y='116.856'><title>Asp37: circFF6600FFFFFF</title></use>
<rect id='aa37_symbol' height='2.5' width='2.5' x='5.87496' y='117.996' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Lys38: boxFF2200000000</title></rect>
<use id='aa37_letter' fill='#000000' x='6.33899' xlink:href='#g275' y='120.063'><title>Lys38: boxFF2200000000</title></use>
<rect id='aa38_symbol' height='2.5' width='2.5' x='5.87496' y='121.203' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Arg39: boxFF6600000000</title></rect>
<use id='aa38_letter' fill='#000000' x='6.39537' xlink:href='#g282' y='123.27'><title>Arg39: boxFF6600000000</title></use>
<rect id='aa39_symbol' height='2.5' width='2.5' x='6.51635' y='124.41' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Tyr40: boxFF6600000000</title></rect>
<use id='aa39_letter' fill='#000000' x='7.01099' xlink:href='#g289' y='126.477'><title>Tyr40: boxFF6600000000</title></use>
<text x='5.805187' y='126.05223' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>40</text><rect id='aa40_symbol' height='2.5' width='2.5' x='8.440519' y='126.97499' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Asn41: boxE00000000000</title></rect>
<use id='aa40_letter' fill='#000000' x='8.88681' xlink:href='#g278' y='129.042'><title>Asn41: boxE00000000000</title></use>
<rect id='aa41_symbol' height='2.5' width='2.5' x='11.647499' y='126.97499' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Cys42: boxE00000000000</title></rect>
<use id='aa41_letter' fill='#000000' x='12.1759' xlink:href='#g267' y='129.042'><title>Cys42: boxE00000000000</title></use>
<rect id='aa42_symbol' height='2.5' width='2.5' x='13.5716' y='124.41' fill='#ccff00' stroke='#000000' stroke-width='0.3'><title>Glu43: boxCCFF00000000</title></rect>
<use id='aa42_letter' fill='#000000' x='14.1468' xlink:href='#g269' y='126.477'><title>Glu43: boxCCFF00000000</title></use>
<circle id='aa43_symbol' r='1.6' cx='15.462999' cy='122.453' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Tyr44: circFF2200FFFFFF</title></circle>
<use id='aa43_letter' fill='#000000' x='14.7076' xlink:href='#g289' y='123.27'><title>Tyr44: circFF2200FFFFFF</title></use>
<circle id='aa44_symbol' r='1.6' cx='15.462999' cy='119.246' fill='#ccff00' stroke='#ffffff' stroke-width='0.3'><title>Ser45: circCCFF00FFFFFF</title></circle>
<use id='aa44_letter' fill='#000000' x='14.8333' xlink:href='#g283' y='120.063'><title>Ser45: circCCFF00FFFFFF</title></use>
<circle id='aa45_symbol' r='1.6' cx='15.462999' cy='116.039' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Gly46: circFF2200FFFFFF</title></circle>
<use id='aa45_letter' fill='#000000' x='14.7109' xlink:href='#g271' y='116.856'><title>Gly46: circFF2200FFFFFF</title></use>
<circle id='aa46_symbol' r='1.6' cx='15.462999' cy='112.832' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Pro47: circAAFF00FFFFFF</title></circle>
<use id='aa46_letter' fill='#000000' x='14.7399' xlink:href='#g280' y='113.649'><title>Pro47: circAAFF00FFFFFF</title></use>
<circle id='aa47_symbol' r='1.6' cx='15.462999' cy='109.625' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Pro48: circFF2200FFFFFF</title></circle>
<use id='aa47_letter' fill='#000000' x='14.7399' xlink:href='#g280' y='110.442'><title>Pro48: circFF2200FFFFFF</title></use>
<rect id='aa48_symbol' height='2.5' width='2.5' x='14.212999' y='105.168' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Lys49: boxAAFF00000000</title></rect>
<use id='aa48_letter' fill='#000000' x='14.677' xlink:href='#g275' y='107.235'><title>Lys49: boxAAFF00000000</title></use>
<rect id='aa49_symbol' height='2.5' width='2.5' x='14.212999' y='101.961' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Pro50: boxFF4400000000</title></rect>
<use id='aa49_letter' fill='#000000' x='14.7399' xlink:href='#g280' y='104.028'><title>Pro50: boxFF4400000000</title></use>
<text x='17.463' y='103.211' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>50</text><circle id='aa50_symbol' r='1.6' cx='15.462999' cy='100.004' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Leu51: circFF2200FFFFFF</title></circle>
<use id='aa50_letter' fill='#000000' x='14.8494' xlink:href='#g276' y='100.821'><title>Leu51: circFF2200FFFFFF</title></use>
<circle id='aa51_symbol' r='1.6' cx='15.462999' cy='96.7972' fill='#ffee00' stroke='#ffffff' stroke-width='0.3'><title>Pro52: circFFEE00FFFFFF</title></circle>
<use id='aa51_letter' fill='#000000' x='14.7399' xlink:href='#g280' y='97.6144'><title>Pro52: circFFEE00FFFFFF</title></use>
<circle id='aa52_symbol' r='1.6' cx='15.462999' cy='93.5902' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Lys53: circAAFF00FFFFFF</title></circle>
<use id='aa52_letter' fill='#000000' x='14.677' xlink:href='#g275' y='94.4074'><title>Lys53: circAAFF00FFFFFF</title></use>
<circle id='aa53_symbol' r='1.6' cx='15.462999' cy='90.3833' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Asp54: circAAFF00FFFFFF</title></circle>
<use id='aa53_letter' fill='#000000' x='14.648' xlink:href='#g268' y='91.2005'><title>Asp54: circAAFF00FFFFFF</title></use>
<circle id='aa54_symbol' r='1.6' cx='15.462999' cy='87.1763' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Gly55: circFF4400000000</title></circle>
<use id='aa54_letter' fill='#000000' x='14.7109' xlink:href='#g271' y='87.9935'><title>Gly55: circFF4400000000</title></use>
<circle id='aa55_symbol' r='1.6' cx='15.462999' cy='83.9694' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Tyr56: circFF6600000000</title></circle>
<use id='aa55_letter' fill='#000000' x='14.7076' xlink:href='#g289' y='84.7866'><title>Tyr56: circFF6600000000</title></use>
<circle id='aa56_symbol' r='1.6' cx='15.462999' cy='80.762505' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Asp57: circAAFF00000000</title></circle>
<use id='aa56_letter' fill='#000000' x='14.648' xlink:href='#g268' y='81.5797'><title>Asp57: circAAFF00000000</title></use>
<circle id='aa57_symbol' r='1.6' cx='15.462999' cy='77.555504' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Leu58: circFF4400000000</title></circle>
<use id='aa57_letter' fill='#000000' x='14.8494' xlink:href='#g276' y='78.3727'><title>Leu58: circFF4400000000</title></use>
<circle id='aa58_symbol' r='1.6' cx='15.462999' cy='74.3486' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Val59: circFF8800000000</title></circle>
<use id='aa58_letter' fill='#000000' x='14.7076' xlink:href='#g286' y='75.1658'><title>Val59: circFF8800000000</title></use>
<circle id='aa59_symbol' r='1.6' cx='15.462999' cy='71.1416' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Gln60: circAAFF00000000</title></circle>
<use id='aa59_letter' fill='#000000' x='14.6367' xlink:href='#g281' y='71.9588'><title>Gln60: circAAFF00000000</title></use>
<text x='17.463' y='71.1416' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>60</text><circle id='aa60_symbol' r='1.6' cx='15.462999' cy='67.9347' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Glu61: circFF2200000000</title></circle>
<use id='aa60_letter' fill='#000000' x='14.7882' xlink:href='#g269' y='68.7519'><title>Glu61: circFF2200000000</title></use>
<circle id='aa61_symbol' r='1.6' cx='16.1044' cy='64.7278' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Leu62: circFF6600000000</title></circle>
<use id='aa61_letter' fill='#000000' x='15.4908' xlink:href='#g276' y='65.545'><title>Leu62: circFF6600000000</title></use>
<circle id='aa62_symbol' r='1.6' cx='18.0286' cy='62.1622' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Cys63: circE00000000000</title></circle>
<use id='aa62_letter' fill='#000000' x='17.307' xlink:href='#g267' y='62.9794'><title>Cys63: circE00000000000</title></use>
<circle id='aa63_symbol' r='1.6' cx='21.2355' cy='62.1622' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Pro64: circE00000000000</title></circle>
<use id='aa63_letter' fill='#000000' x='20.5124' xlink:href='#g280' y='62.9794'><title>Pro64: circE00000000000</title></use>
<circle id='aa64_symbol' r='1.6' cx='23.1597' cy='64.7278' fill='#ffee00' stroke='#000000' stroke-width='0.3'><title>Gly65: circFFEE00000000</title></circle>
<use id='aa64_letter' fill='#000000' x='22.4075' xlink:href='#g271' y='65.545'><title>Gly65: circFFEE00000000</title></use>
<circle id='aa65_symbol' r='1.6' cx='23.801' cy='67.9347' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Phe66: circFF4400000000</title></circle>
<use id='aa65_letter' fill='#000000' x='23.1568' xlink:href='#g270' y='68.7519'><title>Phe66: circFF4400000000</title></use>
<circle id='aa66_symbol' r='1.6' cx='23.801' cy='71.1416' fill='#ffee00' stroke='#000000' stroke-width='0.3'><title>Phe67: circFFEE00000000</title></circle>
<use id='aa66_letter' fill='#000000' x='23.1568' xlink:href='#g270' y='71.9588'><title>Phe67: circFFEE00000000</title></use>
<circle id='aa67_symbol' r='1.6' cx='23.801' cy='74.3486' fill='#ff6600' stroke='#ffffff' stroke-width='0.3'><title>Phe68: circFF6600FFFFFF</title></circle>
<use id='aa67_letter' fill='#000000' x='23.1568' xlink:href='#g270' y='75.1658'><title>Phe68: circFF6600FFFFFF</title></use>
<circle id='aa68_symbol' r='1.6' cx='23.801' cy='77.555504' fill='#ff6600' stroke='#ffffff' stroke-width='0.3'><title>Gly69: circFF6600FFFFFF</title></circle>
<use id='aa68_letter' fill='#000000' x='23.0489' xlink:href='#g271' y='78.3727'><title>Gly69: circFF6600FFFFFF</title></use>
<circle id='aa69_symbol' r='1.6' cx='23.801' cy='80.762505' fill='#ff8800' stroke='#ffffff' stroke-width='0.3'><title>Asn70: circFF8800FFFFFF</title></circle>
<use id='aa69_letter' fill='#000000' x='22.9973' xlink:href='#g278' y='81.5797'><title>Asn70: circFF8800FFFFFF</title></use>
<text x='21.801' y='80.762505' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>70</text><circle id='aa70_symbol' r='1.6' cx='23.801' cy='83.9694' fill='#eeff00' stroke='#ffffff' stroke-width='0.3'><title>Val71: circEEFF00FFFFFF</title></circle>
<use id='aa70_letter' fill='#000000' x='23.0457' xlink:href='#g286' y='84.7866'><title>Val71: circEEFF00FFFFFF</title></use>
<rect id='aa71_symbol' height='2.5' width='2.5' x='22.551' y='85.9263' fill='#55ff00' stroke='#000000' stroke-width='0.3'><title>Ser72: box55FF00000000</title></rect>
<use id='aa71_letter' fill='#000000' x='23.1714' xlink:href='#g283' y='87.9935'><title>Ser72: box55FF00000000</title></use>
<rect id='aa72_symbol' height='2.5' width='2.5' x='22.551' y='89.1333' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Leu73: boxFF8800000000</title></rect>
<use id='aa72_letter' fill='#000000' x='23.1875' xlink:href='#g276' y='91.2005'><title>Leu73: boxFF8800000000</title></use>
<circle id='aa73_symbol' r='1.6' cx='23.801' cy='93.5902' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Cys74: circE00000FFFFFF</title></circle>
<use id='aa73_letter' fill='#000000' x='23.0795' xlink:href='#g267' y='94.4074'><title>Cys74: circE00000FFFFFF</title></use>
<circle id='aa74_symbol' r='1.6' cx='23.801' cy='96.7972' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Cys75: circE00000FFFFFF</title></circle>
<use id='aa74_letter' fill='#000000' x='23.0795' xlink:href='#g267' y='97.6144'><title>Cys75: circE00000FFFFFF</title></use>
<circle id='aa75_symbol' r='1.6' cx='23.801' cy='100.004' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Asp76: circFF2200FFFFFF</title></circle>
<use id='aa75_letter' fill='#000000' x='22.9861' xlink:href='#g268' y='100.821'><title>Asp76: circFF2200FFFFFF</title></use>
<circle id='aa76_symbol' r='1.6' cx='23.801' cy='103.211' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Val77: circAAFF00FFFFFF</title></circle>
<use id='aa76_letter' fill='#000000' x='23.0457' xlink:href='#g286' y='104.028'><title>Val77: circAAFF00FFFFFF</title></use>
<circle id='aa77_symbol' r='1.6' cx='23.801' cy='106.418' fill='#55ff00' stroke='#000000' stroke-width='0.3'><title>Arg78: circ55FF00000000</title></circle>
<use id='aa77_letter' fill='#000000' x='23.0715' xlink:href='#g282' y='107.235'><title>Arg78: circ55FF00000000</title></use>
<circle id='aa78_symbol' r='1.6' cx='23.801' cy='109.625' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Gln79: circE00000000000</title></circle>
<use id='aa78_letter' fill='#000000' x='22.9748' xlink:href='#g281' y='110.442'><title>Gln79: circE00000000000</title></use>
<circle id='aa79_symbol' r='1.6' cx='23.801' cy='112.832' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Leu80: circFF2200000000</title></circle>
<use id='aa79_letter' fill='#000000' x='23.1875' xlink:href='#g276' y='113.649'><title>Leu80: circFF2200000000</title></use>
<text x='21.801' y='112.832' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>80</text><circle id='aa80_symbol' r='1.6' cx='23.801' cy='116.039' fill='#55ff00' stroke='#000000' stroke-width='0.3'><title>Gln81: circ55FF00000000</title></circle>
<use id='aa80_letter' fill='#000000' x='22.9748' xlink:href='#g281' y='116.856'><title>Gln81: circ55FF00000000</title></use>
<circle id='aa81_symbol' r='1.6' cx='23.801' cy='119.246' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Thr82: circFF4400000000</title></circle>
<use id='aa81_letter' fill='#000000' x='23.036' xlink:href='#g284' y='120.063'><title>Thr82: circFF4400000000</title></use>
<circle id='aa82_symbol' r='1.6' cx='23.801' cy='122.453' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Leu83: circE00000000000</title></circle>
<use id='aa82_letter' fill='#000000' x='23.1875' xlink:href='#g276' y='123.27'><title>Leu83: circE00000000000</title></use>
<circle id='aa83_symbol' r='1.6' cx='24.4424' cy='125.66' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Lys84: circAAFF00000000</title></circle>
<use id='aa83_letter' fill='#000000' x='23.6565' xlink:href='#g275' y='126.477'><title>Lys84: circAAFF00000000</title></use>
<circle id='aa84_symbol' r='1.6' cx='26.3666' cy='128.22499' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Asp85: circAAFF00000000</title></circle>
<use id='aa84_letter' fill='#000000' x='25.5516' xlink:href='#g268' y='129.042'><title>Asp85: circAAFF00000000</title></use>
<circle id='aa85_symbol' r='1.6' cx='29.5735' cy='128.22499' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Asn86: circFF6600000000</title></circle>
<use id='aa85_letter' fill='#000000' x='28.7698' xlink:href='#g278' y='129.042'><title>Asn86: circFF6600000000</title></use>
<circle id='aa86_symbol' r='1.6' cx='31.4977' cy='125.66' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Leu87: circFF8800000000</title></circle>
<use id='aa86_letter' fill='#000000' x='30.8841' xlink:href='#g276' y='126.477'><title>Leu87: circFF8800000000</title></use>
<circle id='aa87_symbol' r='1.6' cx='32.1391' cy='122.453' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Gln88: circFF6600000000</title></circle>
<use id='aa87_letter' fill='#000000' x='31.3128' xlink:href='#g281' y='123.27'><title>Gln88: circFF6600000000</title></use>
<circle id='aa88_symbol' r='1.6' cx='32.1391' cy='119.246' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Leu89: circFF4400000000</title></circle>
<use id='aa88_letter' fill='#000000' x='31.5255' xlink:href='#g276' y='120.063'><title>Leu89: circFF4400000000</title></use>
<circle id='aa89_symbol' r='1.6' cx='32.1391' cy='116.039' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Pro90: circE00000000000</title></circle>
<use id='aa89_letter' fill='#000000' x='31.416' xlink:href='#g280' y='116.856'><title>Pro90: circE00000000000</title></use>
<text x='34.1391' y='116.039' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>90</text><circle id='aa90_symbol' r='1.6' cx='32.1391' cy='112.832' fill='#ffee00' stroke='#000000' stroke-width='0.3'><title>Leu91: circFFEE00000000</title></circle>
<use id='aa90_letter' fill='#000000' x='31.5255' xlink:href='#g276' y='113.649'><title>Leu91: circFFEE00000000</title></use>
<circle id='aa91_symbol' r='1.6' cx='32.1391' cy='109.625' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Gln92: circFF2200000000</title></circle>
<use id='aa91_letter' fill='#000000' x='31.3128' xlink:href='#g281' y='110.442'><title>Gln92: circFF2200000000</title></use>
<circle id='aa92_symbol' r='1.6' cx='32.1391' cy='106.418' fill='#ffcc00' stroke='#000000' stroke-width='0.3'><title>Phe93: circFFCC00000000</title></circle>
<use id='aa92_letter' fill='#000000' x='31.4949' xlink:href='#g270' y='107.235'><title>Phe93: circFFCC00000000</title></use>
<circle id='aa93_symbol' r='1.6' cx='32.1391' cy='103.211' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Leu94: circFF2200000000</title></circle>
<use id='aa93_letter' fill='#000000' x='31.5255' xlink:href='#g276' y='104.028'><title>Leu94: circFF2200000000</title></use>
<circle id='aa94_symbol' r='1.6' cx='32.1391' cy='100.004' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Ser95: circFF4400000000</title></circle>
<use id='aa94_letter' fill='#000000' x='31.5094' xlink:href='#g283' y='100.821'><title>Ser95: circFF4400000000</title></use>
<circle id='aa95_symbol' r='1.6' cx='32.1391' cy='96.7972' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Arg96: circE00000FFFFFF</title></circle>
<use id='aa95_letter' fill='#000000' x='31.4095' xlink:href='#g282' y='97.6144'><title>Arg96: circE00000FFFFFF</title></use>
<circle id='aa96_symbol' r='1.6' cx='32.1391' cy='93.5902' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Cys97: circE00000000000</title></circle>
<use id='aa96_letter' fill='#000000' x='31.4176' xlink:href='#g267' y='94.4074'><title>Cys97: circE00000000000</title></use>
<circle id='aa97_symbol' r='1.6' cx='32.1391' cy='90.3833' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Pro98: circE00000000000</title></circle>
<use id='aa97_letter' fill='#000000' x='31.416' xlink:href='#g280' y='91.2005'><title>Pro98: circE00000000000</title></use>
<circle id='aa98_symbol' r='1.6' cx='32.1391' cy='87.1763' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Ser99: circFF2200000000</title></circle>
<use id='aa98_letter' fill='#000000' x='31.5094' xlink:href='#g283' y='87.9935'><title>Ser99: circFF2200000000</title></use>
<circle id='aa99_symbol' r='1.6' cx='32.1391' cy='83.9694' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Cys100: circE00000000000</title></circle>
<use id='aa99_letter' fill='#000000' x='31.4176' xlink:href='#g267' y='84.7866'><title>Cys100: circE00000000000</title></use>
<text x='34.1391' y='83.9694' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>100</text><circle id='aa100_symbol' r='1.6' cx='32.1391' cy='80.762505' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Phe101: circFF2200000000</title></circle>
<use id='aa100_letter' fill='#000000' x='31.4949' xlink:href='#g270' y='81.5797'><title>Phe101: circFF2200000000</title></use>
<circle id='aa101_symbol' r='1.6' cx='32.1391' cy='77.555504' fill='#ccff00' stroke='#000000' stroke-width='0.3'><title>Tyr102: circCCFF00000000</title></circle>
<use id='aa101_letter' fill='#000000' x='31.3837' xlink:href='#g289' y='78.3727'><title>Tyr102: circCCFF00000000</title></use>
<circle id='aa102_symbol' r='1.6' cx='32.1391' cy='74.3486' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Asn103: circE00000000000</title></circle>
<use id='aa102_letter' fill='#000000' x='31.3354' xlink:href='#g278' y='75.1658'><title>Asn103: circE00000000000</title></use>
<circle id='aa103_symbol' r='1.6' cx='32.1391' cy='71.1416' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Leu104: circFF2200000000</title></circle>
<use id='aa103_letter' fill='#000000' x='31.5255' xlink:href='#g276' y='71.9588'><title>Leu104: circFF2200000000</title></use>
<circle id='aa104_symbol' r='1.6' cx='32.1391' cy='67.9347' fill='#eeff00' stroke='#000000' stroke-width='0.3'><title>Leu105: circEEFF00000000</title></circle>
<use id='aa104_letter' fill='#000000' x='31.5255' xlink:href='#g276' y='68.7519'><title>Leu105: circEEFF00000000</title></use>
<circle id='aa105_symbol' r='1.6' cx='32.7805' cy='64.7278' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Asn106: circFF8800000000</title></circle>
<use id='aa105_letter' fill='#000000' x='31.9768' xlink:href='#g278' y='65.545'><title>Asn106: circFF8800000000</title></use>
<circle id='aa106_symbol' r='1.6' cx='34.704597' cy='62.1622' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Leu107: circFF4400000000</title></circle>
<use id='aa106_letter' fill='#000000' x='34.0911' xlink:href='#g276' y='62.9794'><title>Leu107: circFF4400000000</title></use>
<circle id='aa107_symbol' r='1.6' cx='37.9116' cy='62.1622' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Phe108: circFF4400000000</title></circle>
<use id='aa107_letter' fill='#000000' x='37.2674' xlink:href='#g270' y='62.9794'><title>Phe108: circFF4400000000</title></use>
<circle id='aa108_symbol' r='1.6' cx='39.835697' cy='64.7278' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Cys109: circE00000000000</title></circle>
<use id='aa108_letter' fill='#000000' x='39.1142' xlink:href='#g267' y='65.545'><title>Cys109: circE00000000000</title></use>
<circle id='aa109_symbol' r='1.6' cx='40.4771' cy='67.9347' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Glu110: circFF4400000000</title></circle>
<use id='aa109_letter' fill='#000000' x='39.8023' xlink:href='#g269' y='68.7519'><title>Glu110: circFF4400000000</title></use>
<text x='38.51594' y='68.32694' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>110</text><circle id='aa110_symbol' r='1.6' cx='40.4771' cy='71.1416' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Leu111: circFF2200000000</title></circle>
<use id='aa110_letter' fill='#000000' x='39.8636' xlink:href='#g276' y='71.9588'><title>Leu111: circFF2200000000</title></use>
<circle id='aa111_symbol' r='1.6' cx='40.4771' cy='74.3486' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Thr112: circFF2200000000</title></circle>
<use id='aa111_letter' fill='#000000' x='39.7121' xlink:href='#g284' y='75.1658'><title>Thr112: circFF2200000000</title></use>
<circle id='aa112_symbol' r='1.6' cx='40.4771' cy='77.555504' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Cys113: circE00000000000</title></circle>
<use id='aa112_letter' fill='#000000' x='39.7556' xlink:href='#g267' y='78.3727'><title>Cys113: circE00000000000</title></use>
<circle id='aa113_symbol' r='1.6' cx='40.4771' cy='80.762505' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Ser114: circFF4400000000</title></circle>
<use id='aa113_letter' fill='#000000' x='39.8474' xlink:href='#g283' y='81.5797'><title>Ser114: circFF4400000000</title></use>
<circle id='aa114_symbol' r='1.6' cx='40.4771' cy='83.9694' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Pro115: circFF2200FFFFFF</title></circle>
<use id='aa114_letter' fill='#000000' x='39.754' xlink:href='#g280' y='84.7866'><title>Pro115: circFF2200FFFFFF</title></use>
<circle id='aa115_symbol' r='1.6' cx='40.4771' cy='87.1763' fill='#eeff00' stroke='#000000' stroke-width='0.3'><title>Arg116: circEEFF00000000</title></circle>
<use id='aa115_letter' fill='#000000' x='39.7475' xlink:href='#g282' y='87.9935'><title>Arg116: circEEFF00000000</title></use>
<circle id='aa116_symbol' r='1.6' cx='40.4771' cy='90.3833' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Gln117: circFF2200000000</title></circle>
<use id='aa116_letter' fill='#000000' x='39.6509' xlink:href='#g281' y='91.2005'><title>Gln117: circFF2200000000</title></use>
<circle id='aa117_symbol' r='1.6' cx='40.4771' cy='93.5902' fill='#ffcc00' stroke='#000000' stroke-width='0.3'><title>Ser118: circFFCC00000000</title></circle>
<use id='aa117_letter' fill='#000000' x='39.8474' xlink:href='#g283' y='94.4074'><title>Ser118: circFFCC00000000</title></use>
<circle id='aa118_symbol' r='1.6' cx='40.4771' cy='96.7972' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Gln119: circAAFF00000000</title></circle>
<use id='aa118_letter' fill='#000000' x='39.6509' xlink:href='#g281' y='97.6144'><title>Gln119: circAAFF00000000</title></use>
<circle id='aa119_symbol' r='1.6' cx='40.4771' cy='100.004' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Phe120: circE00000FFFFFF</title></circle>
<use id='aa119_letter' fill='#000000' x='39.8329' xlink:href='#g270' y='100.821'><title>Phe120: circE00000FFFFFF</title></use>
<text x='38.4771' y='100.004' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>120</text><rect id='aa120_symbol' height='2.5' width='2.5' x='39.2271' y='101.961' fill='#ffaa00' stroke='#000000' stroke-width='0.3'><title>Leu121: boxFFAA00000000</title></rect>
<use id='aa120_letter' fill='#000000' x='39.8636' xlink:href='#g276' y='104.028'><title>Leu121: boxFFAA00000000</title></use>
<rect id='aa121_symbol' height='2.5' width='2.5' x='39.2271' y='105.168' fill='#ffee00' stroke='#000000' stroke-width='0.3'><title>Asn122: boxFFEE00000000</title></rect>
<use id='aa121_letter' fill='#000000' x='39.6734' xlink:href='#g278' y='107.235'><title>Asn122: boxFFEE00000000</title></use>
<rect id='aa122_symbol' height='2.5' width='2.5' x='39.2271' y='108.375' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Val123: boxFF4400000000</title></rect>
<use id='aa122_letter' fill='#000000' x='39.7218' xlink:href='#g286' y='110.442'><title>Val123: boxFF4400000000</title></use>
<rect id='aa123_symbol' height='2.5' width='2.5' x='39.2271' y='111.582' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Thr124: boxFF6600000000</title></rect>
<use id='aa123_letter' fill='#000000' x='39.7121' xlink:href='#g284' y='113.649'><title>Thr124: boxFF6600000000</title></use>
<rect id='aa124_symbol' height='2.5' width='2.5' x='39.2271' y='114.789' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Ala125: boxAAFF00000000</title></rect>
<use id='aa124_letter' fill='#000000' x='39.7218' xlink:href='#g265' y='116.856'><title>Ala125: boxAAFF00000000</title></use>
<rect id='aa125_symbol' height='2.5' width='2.5' x='39.2271' y='117.996' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Thr126: boxAAFF00000000</title></rect>
<use id='aa125_letter' fill='#000000' x='39.7121' xlink:href='#g284' y='120.063'><title>Thr126: boxAAFF00000000</title></use>
<rect id='aa126_symbol' height='2.5' width='2.5' x='39.2271' y='121.203' fill='#55ff00' stroke='#000000' stroke-width='0.3'><title>Glu127: box55FF00000000</title></rect>
<use id='aa126_letter' fill='#000000' x='39.8023' xlink:href='#g269' y='123.27'><title>Glu127: box55FF00000000</title></use>
<rect id='aa127_symbol' height='2.5' width='2.5' x='39.8685' y='124.41' fill='#00ff00' stroke='#000000' stroke-width='0.3'><title>Asp128: box00FF00000000</title></rect>
<use id='aa127_letter' fill='#000000' x='40.3035' xlink:href='#g268' y='126.477'><title>Asp128: box00FF00000000</title></use>
<rect id='aa128_symbol' height='2.5' width='2.5' x='41.792698' y='126.97499' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Tyr129: boxFF2200000000</title></rect>
<use id='aa128_letter' fill='#000000' x='42.2873' xlink:href='#g289' y='129.042'><title>Tyr129: boxFF2200000000</title></use>
<rect id='aa129_symbol' height='2.5' width='2.5' x='44.9996' y='126.97499' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Val130: boxFF4400000000</title></rect>
<use id='aa129_letter' fill='#000000' x='45.4943' xlink:href='#g286' y='129.042'><title>Val130: boxFF4400000000</title></use>
<text x='46.2496' y='130.22499' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>130</text><circle id='aa130_symbol' r='1.6' cx='48.173798' cy='125.66' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Asp131: circE00000FFFFFF</title></circle>
<use id='aa130_letter' fill='#000000' x='47.3588' xlink:href='#g268' y='126.477'><title>Asp131: circE00000FFFFFF</title></use>
<circle id='aa131_symbol' r='1.6' cx='48.815197' cy='122.453' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Pro132: circE00000FFFFFF</title></circle>
<use id='aa131_letter' fill='#000000' x='48.092' xlink:href='#g280' y='123.27'><title>Pro132: circE00000FFFFFF</title></use>
<circle id='aa132_symbol' r='1.6' cx='48.815197' cy='119.246' fill='#55ff00' stroke='#ffffff' stroke-width='0.3'><title>Val133: circ55FF00FFFFFF</title></circle>
<use id='aa132_letter' fill='#000000' x='48.0598' xlink:href='#g286' y='120.063'><title>Val133: circ55FF00FFFFFF</title></use>
<circle id='aa133_symbol' r='1.6' cx='48.815197' cy='116.039' fill='#ffaa00' stroke='#ffffff' stroke-width='0.3'><title>Thr134: circFFAA00FFFFFF</title></circle>
<use id='aa133_letter' fill='#000000' x='48.0502' xlink:href='#g284' y='116.856'><title>Thr134: circFFAA00FFFFFF</title></use>
<circle id='aa134_symbol' r='1.6' cx='48.815197' cy='112.832' fill='#ff8800' stroke='#ffffff' stroke-width='0.3'><title>Asn135: circFF8800FFFFFF</title></circle>
<use id='aa134_letter' fill='#000000' x='48.0115' xlink:href='#g278' y='113.649'><title>Asn135: circFF8800FFFFFF</title></use>
<circle id='aa135_symbol' r='1.6' cx='48.815197' cy='109.625' fill='#ff8800' stroke='#ffffff' stroke-width='0.3'><title>Gln136: circFF8800FFFFFF</title></circle>
<use id='aa135_letter' fill='#000000' x='47.9889' xlink:href='#g281' y='110.442'><title>Gln136: circFF8800FFFFFF</title></use>
<rect id='aa136_symbol' height='2.5' width='2.5' x='47.565197' y='105.168' fill='#ccff00' stroke='#000000' stroke-width='0.3'><title>Thr137: boxCCFF00000000</title></rect>
<use id='aa136_letter' fill='#000000' x='48.0502' xlink:href='#g284' y='107.235'><title>Thr137: boxCCFF00000000</title></use>
<rect id='aa137_symbol' height='2.5' width='2.5' x='47.565197' y='101.961' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Lys138: boxAAFF00000000</title></rect>
<use id='aa137_letter' fill='#000000' x='48.0292' xlink:href='#g275' y='104.028'><title>Lys138: boxAAFF00000000</title></use>
<rect id='aa138_symbol' height='2.5' width='2.5' x='47.565197' y='98.754' fill='#00ff00' stroke='#000000' stroke-width='0.3'><title>Thr139: box00FF00000000</title></rect>
<use id='aa138_letter' fill='#000000' x='48.0502' xlink:href='#g284' y='100.821'><title>Thr139: box00FF00000000</title></use>
<rect id='aa139_symbol' height='2.5' width='2.5' x='47.565197' y='95.5472' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Asn140: boxFF8800000000</title></rect>
<use id='aa139_letter' fill='#000000' x='48.0115' xlink:href='#g278' y='97.6144'><title>Asn140: boxFF8800000000</title></use>
<text x='50.815197' y='96.7972' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>140</text><rect id='aa140_symbol' height='2.5' width='2.5' x='47.565197' y='92.3402' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Val141: boxFF4400000000</title></rect>
<use id='aa140_letter' fill='#000000' x='48.0598' xlink:href='#g286' y='94.4074'><title>Val141: boxFF4400000000</title></use>
<rect id='aa141_symbol' height='2.5' width='2.5' x='47.565197' y='89.1333' fill='#55ff00' stroke='#000000' stroke-width='0.3'><title>Lys142: box55FF00000000</title></rect>
<use id='aa141_letter' fill='#000000' x='48.0292' xlink:href='#g275' y='91.2005'><title>Lys142: box55FF00000000</title></use>
<rect id='aa142_symbol' height='2.5' width='2.5' x='47.565197' y='85.9263' fill='#ffaa00' stroke='#000000' stroke-width='0.3'><title>Glu143: boxFFAA00000000</title></rect>
<use id='aa142_letter' fill='#000000' x='48.1404' xlink:href='#g269' y='87.9935'><title>Glu143: boxFFAA00000000</title></use>
<rect id='aa143_symbol' height='2.5' width='2.5' x='47.565197' y='82.7194' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Leu144: boxFF4400000000</title></rect>
<use id='aa143_letter' fill='#000000' x='48.2016' xlink:href='#g276' y='84.7866'><title>Leu144: boxFF4400000000</title></use>
<rect id='aa144_symbol' height='2.5' width='2.5' x='47.565197' y='79.512505' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Gln145: boxFF6600000000</title></rect>
<use id='aa144_letter' fill='#000000' x='47.9889' xlink:href='#g281' y='81.5797'><title>Gln145: boxFF6600000000</title></use>
<rect id='aa145_symbol' height='2.5' width='2.5' x='47.565197' y='76.305504' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Tyr146: boxE00000000000</title></rect>
<use id='aa145_letter' fill='#000000' x='48.0598' xlink:href='#g289' y='78.3727'><title>Tyr146: boxE00000000000</title></use>
<rect id='aa146_symbol' height='2.5' width='2.5' x='47.565197' y='73.0986' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Tyr147: boxFF8800000000</title></rect>
<use id='aa146_letter' fill='#000000' x='48.0598' xlink:href='#g289' y='75.1658'><title>Tyr147: boxFF8800000000</title></use>
<rect id='aa147_symbol' height='2.5' width='2.5' x='47.565197' y='69.8916' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Val148: boxFF4400000000</title></rect>
<use id='aa147_letter' fill='#000000' x='48.0598' xlink:href='#g286' y='71.9588'><title>Val148: boxFF4400000000</title></use>
<circle id='aa148_symbol' r='1.6' cx='48.815197' cy='67.9347' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Gly149: circFF6600000000</title></circle>
<use id='aa148_letter' fill='#000000' x='48.063' xlink:href='#g271' y='68.7519'><title>Gly149: circFF6600000000</title></use>
<circle id='aa149_symbol' r='1.6' cx='49.4566' cy='64.7278' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Gln150: circAAFF00000000</title></circle>
<use id='aa149_letter' fill='#000000' x='48.6303' xlink:href='#g281' y='65.545'><title>Gln150: circAAFF00000000</title></use>
<text x='51.41776' y='65.12004' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>150</text><circle id='aa150_symbol' r='1.6' cx='51.3807' cy='62.1622' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Ser151: circAAFF00000000</title></circle>
<use id='aa150_letter' fill='#000000' x='50.751' xlink:href='#g283' y='62.9794'><title>Ser151: circAAFF00000000</title></use>
<circle id='aa151_symbol' r='1.6' cx='54.5877' cy='62.1622' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Phe152: circE00000000000</title></circle>
<use id='aa151_letter' fill='#000000' x='53.9435' xlink:href='#g270' y='62.9794'><title>Phe152: circE00000000000</title></use>
<circle id='aa152_symbol' r='1.6' cx='56.5118' cy='64.7278' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Ala153: circFF4400000000</title></circle>
<use id='aa152_letter' fill='#000000' x='55.7565' xlink:href='#g265' y='65.545'><title>Ala153: circFF4400000000</title></use>
<circle id='aa153_symbol' r='1.6' cx='57.1532' cy='67.9347' fill='#ccff00' stroke='#000000' stroke-width='0.3'><title>Asn154: circCCFF00000000</title></circle>
<use id='aa153_letter' fill='#000000' x='56.3495' xlink:href='#g278' y='68.7519'><title>Asn154: circCCFF00000000</title></use>
<circle id='aa154_symbol' r='1.6' cx='57.1532' cy='71.1416' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Ala155: circFF6600000000</title></circle>
<use id='aa154_letter' fill='#000000' x='56.3979' xlink:href='#g265' y='71.9588'><title>Ala155: circFF6600000000</title></use>
<circle id='aa155_symbol' r='1.6' cx='57.1532' cy='74.3486' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Met156: circFF4400000000</title></circle>
<use id='aa155_letter' fill='#000000' x='56.1659' xlink:href='#g277' y='75.1658'><title>Met156: circFF4400000000</title></use>
<circle id='aa156_symbol' r='1.6' cx='57.1532' cy='77.555504' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Tyr157: circFF2200000000</title></circle>
<use id='aa156_letter' fill='#000000' x='56.3979' xlink:href='#g289' y='78.3727'><title>Tyr157: circFF2200000000</title></use>
<circle id='aa157_symbol' r='1.6' cx='57.1532' cy='80.762505' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Asn158: circFF4400000000</title></circle>
<use id='aa157_letter' fill='#000000' x='56.3495' xlink:href='#g278' y='81.5797'><title>Asn158: circFF4400000000</title></use>
<circle id='aa158_symbol' r='1.6' cx='57.1532' cy='83.9694' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Ala159: circFF2200000000</title></circle>
<use id='aa158_letter' fill='#000000' x='56.3979' xlink:href='#g265' y='84.7866'><title>Ala159: circFF2200000000</title></use>
<circle id='aa159_symbol' r='1.6' cx='57.1532' cy='87.1763' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Cys160: circE00000000000</title></circle>
<use id='aa159_letter' fill='#000000' x='56.4317' xlink:href='#g267' y='87.9935'><title>Cys160: circE00000000000</title></use>
<text x='55.1532' y='87.1763' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>160</text><circle id='aa160_symbol' r='1.6' cx='57.1532' cy='90.3833' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Arg161: circFF8800000000</title></circle>
<use id='aa160_letter' fill='#000000' x='56.4236' xlink:href='#g282' y='91.2005'><title>Arg161: circFF8800000000</title></use>
<circle id='aa161_symbol' r='1.6' cx='57.1532' cy='93.5902' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Asp162: circFF2200FFFFFF</title></circle>
<use id='aa161_letter' fill='#000000' x='56.3382' xlink:href='#g268' y='94.4074'><title>Asp162: circFF2200FFFFFF</title></use>
<circle id='aa162_symbol' r='1.6' cx='57.1532' cy='96.7972' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Val163: circE00000FFFFFF</title></circle>
<use id='aa162_letter' fill='#000000' x='56.3979' xlink:href='#g286' y='97.6144'><title>Val163: circE00000FFFFFF</title></use>
<circle id='aa163_symbol' r='1.6' cx='57.1532' cy='100.004' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Glu164: circFF4400FFFFFF</title></circle>
<use id='aa163_letter' fill='#000000' x='56.4784' xlink:href='#g269' y='100.821'><title>Glu164: circFF4400FFFFFF</title></use>
<circle id='aa164_symbol' r='1.6' cx='57.1532' cy='103.211' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Ala165: circFF4400FFFFFF</title></circle>
<use id='aa164_letter' fill='#000000' x='56.3979' xlink:href='#g265' y='104.028'><title>Ala165: circFF4400FFFFFF</title></use>
<circle id='aa165_symbol' r='1.6' cx='57.1532' cy='106.418' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Pro166: circE00000FFFFFF</title></circle>
<use id='aa165_letter' fill='#000000' x='56.4301' xlink:href='#g280' y='107.235'><title>Pro166: circE00000FFFFFF</title></use>
<circle id='aa166_symbol' r='1.6' cx='57.1532' cy='109.625' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Ser167: circFF2200FFFFFF</title></circle>
<use id='aa166_letter' fill='#000000' x='56.5235' xlink:href='#g283' y='110.442'><title>Ser167: circFF2200FFFFFF</title></use>
<circle id='aa167_symbol' r='1.6' cx='57.1532' cy='112.832' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Ser168: circFF4400FFFFFF</title></circle>
<use id='aa167_letter' fill='#000000' x='56.5235' xlink:href='#g283' y='113.649'><title>Ser168: circFF4400FFFFFF</title></use>
<circle id='aa168_symbol' r='1.6' cx='57.1532' cy='116.039' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Asn169: circE00000FFFFFF</title></circle>
<use id='aa168_letter' fill='#000000' x='56.3495' xlink:href='#g278' y='116.856'><title>Asn169: circE00000FFFFFF</title></use>
<circle id='aa169_symbol' r='1.6' cx='57.1532' cy='119.246' fill='#ffee00' stroke='#ffffff' stroke-width='0.3'><title>Asp170: circFFEE00FFFFFF</title></circle>
<use id='aa169_letter' fill='#000000' x='56.3382' xlink:href='#g268' y='120.063'><title>Asp170: circFFEE00FFFFFF</title></use>
<text x='55.1532' y='119.246' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>170</text><circle id='aa170_symbol' r='1.6' cx='57.1532' cy='122.453' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Lys171: circFF4400FFFFFF</title></circle>
<use id='aa170_letter' fill='#000000' x='56.3672' xlink:href='#g275' y='123.27'><title>Lys171: circFF4400FFFFFF</title></use>
<circle id='aa171_symbol' r='1.6' cx='57.794598' cy='125.66' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Ala172: circFF2200000000</title></circle>
<use id='aa171_letter' fill='#000000' x='57.0392' xlink:href='#g265' y='126.477'><title>Ala172: circFF2200000000</title></use>
<circle id='aa172_symbol' r='1.6' cx='59.7188' cy='128.22499' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Leu173: circFF2200000000</title></circle>
<use id='aa172_letter' fill='#000000' x='59.1052' xlink:href='#g276' y='129.042'><title>Leu173: circFF2200000000</title></use>
<circle id='aa173_symbol' r='1.6' cx='62.925697' cy='128.22499' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Gly174: circFF6600000000</title></circle>
<use id='aa173_letter' fill='#000000' x='62.1736' xlink:href='#g271' y='129.042'><title>Gly174: circFF6600000000</title></use>
<circle id='aa174_symbol' r='1.6' cx='64.8499' cy='125.66' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Leu175: circFF6600000000</title></circle>
<use id='aa174_letter' fill='#000000' x='64.2363' xlink:href='#g276' y='126.477'><title>Leu175: circFF6600000000</title></use>
<circle id='aa175_symbol' r='1.6' cx='65.4913' cy='122.453' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Leu176: circFF2200000000</title></circle>
<use id='aa175_letter' fill='#000000' x='64.8777' xlink:href='#g276' y='123.27'><title>Leu176: circFF2200000000</title></use>
<circle id='aa176_symbol' r='1.6' cx='65.4913' cy='119.246' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Cys177: circE00000000000</title></circle>
<use id='aa176_letter' fill='#000000' x='64.7697' xlink:href='#g267' y='120.063'><title>Cys177: circE00000000000</title></use>
<circle id='aa177_symbol' r='1.6' cx='65.4913' cy='116.039' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Gly178: circE00000FFFFFF</title></circle>
<use id='aa177_letter' fill='#000000' x='64.7391' xlink:href='#g271' y='116.856'><title>Gly178: circE00000FFFFFF</title></use>
<circle id='aa178_symbol' r='1.6' cx='65.4913' cy='112.832' fill='#ff6600' stroke='#ffffff' stroke-width='0.3'><title>Lys179: circFF6600FFFFFF</title></circle>
<use id='aa178_letter' fill='#000000' x='64.7053' xlink:href='#g275' y='113.649'><title>Lys179: circFF6600FFFFFF</title></use>
<circle id='aa179_symbol' r='1.6' cx='65.4913' cy='109.625' fill='#ffaa00' stroke='#000000' stroke-width='0.3'><title>Asp180: circFFAA00000000</title></circle>
<use id='aa179_letter' fill='#000000' x='64.6763' xlink:href='#g268' y='110.442'><title>Asp180: circFFAA00000000</title></use>
<text x='67.4913' y='109.625' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>180</text><circle id='aa180_symbol' r='1.6' cx='65.4913' cy='106.418' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Ala181: circFF4400000000</title></circle>
<use id='aa180_letter' fill='#000000' x='64.7359' xlink:href='#g265' y='107.235'><title>Ala181: circFF4400000000</title></use>
<circle id='aa181_symbol' r='1.6' cx='65.4913' cy='103.211' fill='#ffaa00' stroke='#000000' stroke-width='0.3'><title>Asp182: circFFAA00000000</title></circle>
<use id='aa181_letter' fill='#000000' x='64.6763' xlink:href='#g268' y='104.028'><title>Asp182: circFFAA00000000</title></use>
<circle id='aa182_symbol' r='1.6' cx='65.4913' cy='100.004' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Ala183: circFF8800000000</title></circle>
<use id='aa182_letter' fill='#000000' x='64.7359' xlink:href='#g265' y='100.821'><title>Ala183: circFF8800000000</title></use>
<circle id='aa183_symbol' r='1.6' cx='65.4913' cy='96.7972' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Cys184: circE00000000000</title></circle>
<use id='aa183_letter' fill='#000000' x='64.7697' xlink:href='#g267' y='97.6144'><title>Cys184: circE00000000000</title></use>
<circle id='aa184_symbol' r='1.6' cx='65.4913' cy='93.5902' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Asn185: circFF4400000000</title></circle>
<use id='aa184_letter' fill='#000000' x='64.6876' xlink:href='#g278' y='94.4074'><title>Asn185: circFF4400000000</title></use>
<circle id='aa185_symbol' r='1.6' cx='65.4913' cy='90.3833' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Ala186: circFF4400000000</title></circle>
<use id='aa185_letter' fill='#000000' x='64.7359' xlink:href='#g265' y='91.2005'><title>Ala186: circFF4400000000</title></use>
<circle id='aa186_symbol' r='1.6' cx='65.4913' cy='87.1763' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Thr187: circFF4400000000</title></circle>
<use id='aa186_letter' fill='#000000' x='64.7262' xlink:href='#g284' y='87.9935'><title>Thr187: circFF4400000000</title></use>
<circle id='aa187_symbol' r='1.6' cx='65.4913' cy='83.9694' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Asn188: circFF4400000000</title></circle>
<use id='aa187_letter' fill='#000000' x='64.6876' xlink:href='#g278' y='84.7866'><title>Asn188: circFF4400000000</title></use>
<circle id='aa188_symbol' r='1.6' cx='65.4913' cy='80.762505' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Trp189: circFF2200000000</title></circle>
<use id='aa188_letter' fill='#000000' x='64.4298' xlink:href='#g287' y='81.5797'><title>Trp189: circFF2200000000</title></use>
<circle id='aa189_symbol' r='1.6' cx='65.4913' cy='77.555504' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Ile190: circFF2200000000</title></circle>
<use id='aa189_letter' fill='#000000' x='65.1451' xlink:href='#g273' y='78.3727'><title>Ile190: circFF2200000000</title></use>
<text x='67.4913' y='77.555504' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>190</text><circle id='aa190_symbol' r='1.6' cx='65.4913' cy='74.3486' fill='#ccff00' stroke='#000000' stroke-width='0.3'><title>Glu191: circCCFF00000000</title></circle>
<use id='aa190_letter' fill='#000000' x='64.8165' xlink:href='#g269' y='75.1658'><title>Glu191: circCCFF00000000</title></use>
<circle id='aa191_symbol' r='1.6' cx='65.4913' cy='71.1416' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Tyr192: circFF2200000000</title></circle>
<use id='aa191_letter' fill='#000000' x='64.7359' xlink:href='#g289' y='71.9588'><title>Tyr192: circFF2200000000</title></use>
<circle id='aa192_symbol' r='1.6' cx='65.4913' cy='67.9347' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Met193: circE00000000000</title></circle>
<use id='aa192_letter' fill='#000000' x='64.5039' xlink:href='#g277' y='68.7519'><title>Met193: circE00000000000</title></use>
<circle id='aa193_symbol' r='1.6' cx='66.1327' cy='64.7278' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Phe194: circFF2200000000</title></circle>
<use id='aa193_letter' fill='#000000' x='65.4884' xlink:href='#g270' y='65.545'><title>Phe194: circFF2200000000</title></use>
<circle id='aa194_symbol' r='1.6' cx='68.0568' cy='62.1622' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Asn195: circFF4400000000</title></circle>
<use id='aa194_letter' fill='#000000' x='67.2531' xlink:href='#g278' y='62.9794'><title>Asn195: circFF4400000000</title></use>
<circle id='aa195_symbol' r='1.6' cx='71.2638' cy='62.1622' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Lys196: circFF4400000000</title></circle>
<use id='aa195_letter' fill='#000000' x='70.4778' xlink:href='#g275' y='62.9794'><title>Lys196: circFF4400000000</title></use>
<circle id='aa196_symbol' r='1.6' cx='73.1879' cy='64.7278' fill='#ffaa00' stroke='#000000' stroke-width='0.3'><title>Asp197: circFFAA00000000</title></circle>
<use id='aa196_letter' fill='#000000' x='72.3729' xlink:href='#g268' y='65.545'><title>Asp197: circFFAA00000000</title></use>
<circle id='aa197_symbol' r='1.6' cx='73.8293' cy='67.9347' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Asn198: circE00000000000</title></circle>
<use id='aa197_letter' fill='#000000' x='73.0256' xlink:href='#g278' y='68.7519'><title>Asn198: circE00000000000</title></use>
<circle id='aa198_symbol' r='1.6' cx='73.8293' cy='71.1416' fill='#ccff00' stroke='#000000' stroke-width='0.3'><title>Gly199: circCCFF00000000</title></circle>
<use id='aa198_letter' fill='#000000' x='73.0772' xlink:href='#g271' y='71.9588'><title>Gly199: circCCFF00000000</title></use>
<circle id='aa199_symbol' r='1.6' cx='73.8293' cy='74.3486' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Gln200: circFF2200FFFFFF</title></circle>
<use id='aa199_letter' fill='#000000' x='73.0031' xlink:href='#g281' y='75.1658'><title>Gln200: circFF2200FFFFFF</title></use>
<text x='71.8293' y='74.3486' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>200</text><circle id='aa200_symbol' r='1.6' cx='73.8293' cy='77.555504' fill='#ff6600' stroke='#ffffff' stroke-width='0.3'><title>Ala201: circFF6600FFFFFF</title></circle>
<use id='aa200_letter' fill='#000000' x='73.0739' xlink:href='#g265' y='78.3727'><title>Ala201: circFF6600FFFFFF</title></use>
<circle id='aa201_symbol' r='1.6' cx='73.8293' cy='80.762505' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Pro202: circE00000FFFFFF</title></circle>
<use id='aa201_letter' fill='#000000' x='73.1062' xlink:href='#g280' y='81.5797'><title>Pro202: circE00000FFFFFF</title></use>
<circle id='aa202_symbol' r='1.6' cx='73.8293' cy='83.9694' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Phe203: circE00000FFFFFF</title></circle>
<use id='aa202_letter' fill='#000000' x='73.1851' xlink:href='#g270' y='84.7866'><title>Phe203: circE00000FFFFFF</title></use>
<rect id='aa203_symbol' height='2.5' width='2.5' x='72.5793' y='85.9263' fill='#eeff00' stroke='#000000' stroke-width='0.3'><title>Thr204: boxEEFF00000000</title></rect>
<use id='aa203_letter' fill='#000000' x='73.0643' xlink:href='#g284' y='87.9935'><title>Thr204: boxEEFF00000000</title></use>
<rect id='aa204_symbol' height='2.5' width='2.5' x='72.5793' y='89.1333' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Ile205: boxE00000000000</title></rect>
<use id='aa204_letter' fill='#000000' x='73.4832' xlink:href='#g273' y='91.2005'><title>Ile205: boxE00000000000</title></use>
<rect id='aa205_symbol' height='2.5' width='2.5' x='72.5793' y='92.3402' fill='#ffcc00' stroke='#000000' stroke-width='0.3'><title>Thr206: boxFFCC00000000</title></rect>
<use id='aa205_letter' fill='#000000' x='73.0643' xlink:href='#g284' y='94.4074'><title>Thr206: boxFFCC00000000</title></use>
<rect id='aa206_symbol' height='2.5' width='2.5' x='72.5793' y='95.5472' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Pro207: boxFF2200000000</title></rect>
<use id='aa206_letter' fill='#000000' x='73.1062' xlink:href='#g280' y='97.6144'><title>Pro207: boxFF2200000000</title></use>
<rect id='aa207_symbol' height='2.5' width='2.5' x='72.5793' y='98.754' fill='#ffcc00' stroke='#000000' stroke-width='0.3'><title>Val208: boxFFCC00000000</title></rect>
<use id='aa207_letter' fill='#000000' x='73.0739' xlink:href='#g286' y='100.821'><title>Val208: boxFFCC00000000</title></use>
<rect id='aa208_symbol' height='2.5' width='2.5' x='72.5793' y='101.961' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Phe209: boxFF6600000000</title></rect>
<use id='aa208_letter' fill='#000000' x='73.1851' xlink:href='#g270' y='104.028'><title>Phe209: boxFF6600000000</title></use>
<circle id='aa209_symbol' r='1.6' cx='73.8293' cy='106.418' fill='#eeff00' stroke='#ffffff' stroke-width='0.3'><title>Ser210: circEEFF00FFFFFF</title></circle>
<use id='aa209_letter' fill='#000000' x='73.1996' xlink:href='#g283' y='107.235'><title>Ser210: circEEFF00FFFFFF</title></use>
<text x='71.8293' y='106.418' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>210</text><circle id='aa210_symbol' r='1.6' cx='73.8293' cy='109.625' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Asp211: circFF2200FFFFFF</title></circle>
<use id='aa210_letter' fill='#000000' x='73.0143' xlink:href='#g268' y='110.442'><title>Asp211: circFF2200FFFFFF</title></use>
<circle id='aa211_symbol' r='1.6' cx='73.8293' cy='112.832' fill='#00ff00' stroke='#ffffff' stroke-width='0.3'><title>Phe212: circ00FF00FFFFFF</title></circle>
<use id='aa211_letter' fill='#000000' x='73.1851' xlink:href='#g270' y='113.649'><title>Phe212: circ00FF00FFFFFF</title></use>
<circle id='aa212_symbol' r='1.6' cx='73.8293' cy='116.039' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Pro213: circAAFF00FFFFFF</title></circle>
<use id='aa212_letter' fill='#000000' x='73.1062' xlink:href='#g280' y='116.856'><title>Pro213: circAAFF00FFFFFF</title></use>
<circle id='aa213_symbol' r='1.6' cx='73.8293' cy='119.246' fill='#55ff00' stroke='#ffffff' stroke-width='0.3'><title>Val214: circ55FF00FFFFFF</title></circle>
<use id='aa213_letter' fill='#000000' x='73.0739' xlink:href='#g286' y='120.063'><title>Val214: circ55FF00FFFFFF</title></use>
<circle id='aa214_symbol' r='1.6' cx='73.8293' cy='122.453' fill='#00ff00' stroke='#ffffff' stroke-width='0.3'><title>His215: circ00FF00FFFFFF</title></circle>
<use id='aa214_letter' fill='#000000' x='73.0256' xlink:href='#g272' y='123.27'><title>His215: circ00FF00FFFFFF</title></use>
<circle id='aa215_symbol' r='1.6' cx='74.470695' cy='125.66' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Gly216: circAAFF00FFFFFF</title></circle>
<use id='aa215_letter' fill='#000000' x='73.7186' xlink:href='#g271' y='126.477'><title>Gly216: circAAFF00FFFFFF</title></use>
<circle id='aa216_symbol' r='1.6' cx='76.3949' cy='128.22499' fill='#ff8800' stroke='#ffffff' stroke-width='0.3'><title>Met217: circFF8800FFFFFF</title></circle>
<use id='aa216_letter' fill='#000000' x='75.4075' xlink:href='#g277' y='129.042'><title>Met217: circFF8800FFFFFF</title></use>
<circle id='aa217_symbol' r='1.6' cx='79.6018' cy='128.22499' fill='#55ff00' stroke='#ffffff' stroke-width='0.3'><title>Glu218: circ55FF00FFFFFF</title></circle>
<use id='aa217_letter' fill='#000000' x='78.927' xlink:href='#g269' y='129.042'><title>Glu218: circ55FF00FFFFFF</title></use>
<circle id='aa218_symbol' r='1.6' cx='81.526' cy='125.66' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Pro219: circFF4400FFFFFF</title></circle>
<use id='aa218_letter' fill='#000000' x='80.8028' xlink:href='#g280' y='126.477'><title>Pro219: circFF4400FFFFFF</title></use>
<circle id='aa219_symbol' r='1.6' cx='82.1674' cy='122.453' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Met220: circFF2200FFFFFF</title></circle>
<use id='aa219_letter' fill='#000000' x='81.18' xlink:href='#g277' y='123.27'><title>Met220: circFF2200FFFFFF</title></use>
<text x='84.128555' y='122.84523' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>220</text><circle id='aa220_symbol' r='1.6' cx='82.1674' cy='119.246' fill='#ffee00' stroke='#ffffff' stroke-width='0.3'><title>Asn221: circFFEE00FFFFFF</title></circle>
<use id='aa220_letter' fill='#000000' x='81.3636' xlink:href='#g278' y='120.063'><title>Asn221: circFFEE00FFFFFF</title></use>
<circle id='aa221_symbol' r='1.6' cx='82.1674' cy='116.039' fill='#ff8800' stroke='#ffffff' stroke-width='0.3'><title>Asn222: circFF8800FFFFFF</title></circle>
<use id='aa221_letter' fill='#000000' x='81.3636' xlink:href='#g278' y='116.856'><title>Asn222: circFF8800FFFFFF</title></use>
<circle id='aa222_symbol' r='1.6' cx='82.1674' cy='112.832' fill='#55ff00' stroke='#ffffff' stroke-width='0.3'><title>Ala223: circ55FF00FFFFFF</title></circle>
<use id='aa222_letter' fill='#000000' x='81.412' xlink:href='#g265' y='113.649'><title>Ala223: circ55FF00FFFFFF</title></use>
<circle id='aa223_symbol' r='1.6' cx='82.1674' cy='109.625' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Thr224: circFF4400FFFFFF</title></circle>
<use id='aa223_letter' fill='#000000' x='81.4023' xlink:href='#g284' y='110.442'><title>Thr224: circFF4400FFFFFF</title></use>
<circle id='aa224_symbol' r='1.6' cx='82.1674' cy='106.418' fill='#eeff00' stroke='#ffffff' stroke-width='0.3'><title>Lys225: circEEFF00FFFFFF</title></circle>
<use id='aa224_letter' fill='#000000' x='81.3814' xlink:href='#g275' y='107.235'><title>Lys225: circEEFF00FFFFFF</title></use>
<circle id='aa225_symbol' r='1.6' cx='82.1674' cy='103.211' fill='#ffee00' stroke='#ffffff' stroke-width='0.3'><title>Gly226: circFFEE00FFFFFF</title></circle>
<use id='aa225_letter' fill='#000000' x='81.4152' xlink:href='#g271' y='104.028'><title>Gly226: circFFEE00FFFFFF</title></use>
<circle id='aa226_symbol' r='1.6' cx='82.1674' cy='100.004' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Cys227: circE00000FFFFFF</title></circle>
<use id='aa226_letter' fill='#000000' x='81.4458' xlink:href='#g267' y='100.821'><title>Cys227: circE00000FFFFFF</title></use>
<circle id='aa227_symbol' r='1.6' cx='82.1674' cy='96.7972' fill='#ff8800' stroke='#ffffff' stroke-width='0.3'><title>Asp228: circFF8800FFFFFF</title></circle>
<use id='aa227_letter' fill='#000000' x='81.3524' xlink:href='#g268' y='97.6144'><title>Asp228: circFF8800FFFFFF</title></use>
<circle id='aa228_symbol' r='1.6' cx='82.1674' cy='93.5902' fill='#ff6600' stroke='#ffffff' stroke-width='0.3'><title>Glu229: circFF6600FFFFFF</title></circle>
<use id='aa228_letter' fill='#000000' x='81.4925' xlink:href='#g269' y='94.4074'><title>Glu229: circFF6600FFFFFF</title></use>
<circle id='aa229_symbol' r='1.6' cx='82.1674' cy='90.3833' fill='#ff8800' stroke='#ffffff' stroke-width='0.3'><title>Ser230: circFF8800FFFFFF</title></circle>
<use id='aa229_letter' fill='#000000' x='81.5377' xlink:href='#g283' y='91.2005'><title>Ser230: circFF8800FFFFFF</title></use>
<text x='84.1674' y='90.3833' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>230</text><circle id='aa230_symbol' r='1.6' cx='82.1674' cy='87.1763' fill='#ffcc00' stroke='#ffffff' stroke-width='0.3'><title>Val231: circFFCC00FFFFFF</title></circle>
<use id='aa230_letter' fill='#000000' x='81.412' xlink:href='#g286' y='87.9935'><title>Val231: circFFCC00FFFFFF</title></use>
<circle id='aa231_symbol' r='1.6' cx='82.1674' cy='83.9694' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Asp232: circFF4400FFFFFF</title></circle>
<use id='aa231_letter' fill='#000000' x='81.3524' xlink:href='#g268' y='84.7866'><title>Asp232: circFF4400FFFFFF</title></use>
<circle id='aa232_symbol' r='1.6' cx='82.1674' cy='80.762505' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Glu233: circFF4400FFFFFF</title></circle>
<use id='aa232_letter' fill='#000000' x='81.4925' xlink:href='#g269' y='81.5797'><title>Glu233: circFF4400FFFFFF</title></use>
<circle id='aa233_symbol' r='1.6' cx='82.1674' cy='77.555504' fill='#ffee00' stroke='#ffffff' stroke-width='0.3'><title>Val234: circFFEE00FFFFFF</title></circle>
<use id='aa233_letter' fill='#000000' x='81.412' xlink:href='#g286' y='78.3727'><title>Val234: circFFEE00FFFFFF</title></use>
<circle id='aa234_symbol' r='1.6' cx='82.1674' cy='74.3486' fill='#ff6600' stroke='#ffffff' stroke-width='0.3'><title>Thr235: circFF6600FFFFFF</title></circle>
<use id='aa234_letter' fill='#000000' x='81.4023' xlink:href='#g284' y='75.1658'><title>Thr235: circFF6600FFFFFF</title></use>
<circle id='aa235_symbol' r='1.6' cx='82.1674' cy='71.1416' fill='#ffaa00' stroke='#ffffff' stroke-width='0.3'><title>Ala236: circFFAA00FFFFFF</title></circle>
<use id='aa235_letter' fill='#000000' x='81.412' xlink:href='#g265' y='71.9588'><title>Ala236: circFFAA00FFFFFF</title></use>
<circle id='aa236_symbol' r='1.6' cx='82.1674' cy='67.9347' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Pro237: circFF4400FFFFFF</title></circle>
<use id='aa236_letter' fill='#000000' x='81.4442' xlink:href='#g280' y='68.7519'><title>Pro237: circFF4400FFFFFF</title></use>
<circle id='aa237_symbol' r='1.6' cx='82.8087' cy='64.7278' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Cys238: circE00000FFFFFF</title></circle>
<use id='aa237_letter' fill='#000000' x='82.0872' xlink:href='#g267' y='65.545'><title>Cys238: circE00000FFFFFF</title></use>
<circle id='aa238_symbol' r='1.6' cx='84.732895' cy='62.1622' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Ser239: circFF2200000000</title></circle>
<use id='aa238_letter' fill='#000000' x='84.1032' xlink:href='#g283' y='62.9794'><title>Ser239: circFF2200000000</title></use>
<circle id='aa239_symbol' r='1.6' cx='87.9398' cy='62.1622' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Cys240: circE00000000000</title></circle>
<use id='aa239_letter' fill='#000000' x='87.2183' xlink:href='#g267' y='62.9794'><title>Cys240: circE00000000000</title></use>
<text x='87.9398' y='64.1622' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>240</text><circle id='aa240_symbol' r='1.6' cx='89.864' cy='64.7278' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Gln241: circFF2200000000</title></circle>
<use id='aa240_letter' fill='#000000' x='89.0378' xlink:href='#g281' y='65.545'><title>Gln241: circFF2200000000</title></use>
<circle id='aa241_symbol' r='1.6' cx='90.5054' cy='67.9347' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Asp242: circE00000000000</title></circle>
<use id='aa241_letter' fill='#000000' x='89.6904' xlink:href='#g268' y='68.7519'><title>Asp242: circE00000000000</title></use>
<circle id='aa242_symbol' r='1.6' cx='90.5054' cy='71.1416' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Cys243: circE00000000000</title></circle>
<use id='aa242_letter' fill='#000000' x='89.7839' xlink:href='#g267' y='71.9588'><title>Cys243: circE00000000000</title></use>
<circle id='aa243_symbol' r='1.6' cx='90.5054' cy='74.3486' fill='#ccff00' stroke='#000000' stroke-width='0.3'><title>Ser244: circCCFF00000000</title></circle>
<use id='aa243_letter' fill='#000000' x='89.8757' xlink:href='#g283' y='75.1658'><title>Ser244: circCCFF00000000</title></use>
<circle id='aa244_symbol' r='1.6' cx='90.5054' cy='77.555504' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Ile245: circAAFF00000000</title></circle>
<use id='aa244_letter' fill='#000000' x='90.1592' xlink:href='#g273' y='78.3727'><title>Ile245: circAAFF00000000</title></use>
<circle id='aa245_symbol' r='1.6' cx='90.5054' cy='80.762505' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Val246: circFF8800000000</title></circle>
<use id='aa245_letter' fill='#000000' x='89.75' xlink:href='#g286' y='81.5797'><title>Val246: circFF8800000000</title></use>
<circle id='aa246_symbol' r='1.6' cx='90.5054' cy='83.9694' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Cys247: circE00000000000</title></circle>
<use id='aa246_letter' fill='#000000' x='89.7839' xlink:href='#g267' y='84.7866'><title>Cys247: circE00000000000</title></use>
<circle id='aa247_symbol' r='1.6' cx='90.5054' cy='87.1763' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Gly248: circFF4400FFFFFF</title></circle>
<use id='aa247_letter' fill='#000000' x='89.7533' xlink:href='#g271' y='87.9935'><title>Gly248: circFF4400FFFFFF</title></use>
<circle id='aa248_symbol' r='1.6' cx='90.5054' cy='90.3833' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Pro249: circE00000FFFFFF</title></circle>
<use id='aa248_letter' fill='#000000' x='89.7823' xlink:href='#g280' y='91.2005'><title>Pro249: circE00000FFFFFF</title></use>
<circle id='aa249_symbol' r='1.6' cx='90.5054' cy='93.5902' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Lys250: circAAFF00FFFFFF</title></circle>
<use id='aa249_letter' fill='#000000' x='89.7194' xlink:href='#g275' y='94.4074'><title>Lys250: circAAFF00FFFFFF</title></use>
<text x='88.5054' y='93.5902' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>250</text><circle id='aa250_symbol' r='1.6' cx='90.5054' cy='96.7972' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Pro251: circFF2200FFFFFF</title></circle>
<use id='aa250_letter' fill='#000000' x='89.7823' xlink:href='#g280' y='97.6144'><title>Pro251: circFF2200FFFFFF</title></use>
<circle id='aa251_symbol' r='1.6' cx='90.5054' cy='100.004' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Gln252: circAAFF00FFFFFF</title></circle>
<use id='aa251_letter' fill='#000000' x='89.6791' xlink:href='#g281' y='100.821'><title>Gln252: circAAFF00FFFFFF</title></use>
<circle id='aa252_symbol' r='1.6' cx='90.5054' cy='103.211' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Pro253: circE00000FFFFFF</title></circle>
<use id='aa252_letter' fill='#000000' x='89.7823' xlink:href='#g280' y='104.028'><title>Pro253: circE00000FFFFFF</title></use>
<circle id='aa253_symbol' r='1.6' cx='90.5054' cy='106.418' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Pro254: circFF2200FFFFFF</title></circle>
<use id='aa253_letter' fill='#000000' x='89.7823' xlink:href='#g280' y='107.235'><title>Pro254: circFF2200FFFFFF</title></use>
<circle id='aa254_symbol' r='1.6' cx='90.5054' cy='109.625' fill='#ff8800' stroke='#ffffff' stroke-width='0.3'><title>Pro255: circFF8800FFFFFF</title></circle>
<use id='aa254_letter' fill='#000000' x='89.7823' xlink:href='#g280' y='110.442'><title>Pro255: circFF8800FFFFFF</title></use>
<circle id='aa255_symbol' r='1.6' cx='90.5054' cy='112.832' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Pro256: circAAFF00FFFFFF</title></circle>
<use id='aa255_letter' fill='#000000' x='89.7823' xlink:href='#g280' y='113.649'><title>Pro256: circAAFF00FFFFFF</title></use>
<circle id='aa256_symbol' r='1.6' cx='90.5054' cy='116.039' fill='#ff6600' stroke='#ffffff' stroke-width='0.3'><title>Pro257: circFF6600FFFFFF</title></circle>
<use id='aa256_letter' fill='#000000' x='89.7823' xlink:href='#g280' y='116.856'><title>Pro257: circFF6600FFFFFF</title></use>
<circle id='aa257_symbol' r='1.6' cx='90.5054' cy='119.246' fill='#00ff00' stroke='#ffffff' stroke-width='0.3'><title>Ala258: circ00FF00FFFFFF</title></circle>
<use id='aa257_letter' fill='#000000' x='89.75' xlink:href='#g265' y='120.063'><title>Ala258: circ00FF00FFFFFF</title></use>
<circle id='aa258_symbol' r='1.6' cx='90.5054' cy='122.453' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Pro259: circFF4400FFFFFF</title></circle>
<use id='aa258_letter' fill='#000000' x='89.7823' xlink:href='#g280' y='123.27'><title>Pro259: circFF4400FFFFFF</title></use>
<circle id='aa259_symbol' r='1.6' cx='90.5054' cy='125.66' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Trp260: circFF2200FFFFFF</title></circle>
<use id='aa259_letter' fill='#000000' x='89.4439' xlink:href='#g287' y='126.477'><title>Trp260: circFF2200FFFFFF</title></use>
<text x='88.5054' y='125.66' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>260</text><rect id='aa260_symbol' height='2.5' width='2.5' x='89.2554' y='127.61699' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Thr261: boxAAFF00000000</title></rect>
<use id='aa260_letter' fill='#000000' x='89.7404' xlink:href='#g284' y='129.684'><title>Thr261: boxAAFF00000000</title></use>
<rect id='aa261_symbol' height='2.5' width='2.5' x='89.2554' y='130.823' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Ile262: boxFF2200000000</title></rect>
<use id='aa261_letter' fill='#000000' x='90.1592' xlink:href='#g273' y='132.891'><title>Ile262: boxFF2200000000</title></use>
<rect id='aa262_symbol' height='2.5' width='2.5' x='89.2554' y='134.03' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Leu263: boxFF4400000000</title></rect>
<use id='aa262_letter' fill='#000000' x='89.8918' xlink:href='#g276' y='136.098'><title>Leu263: boxFF4400000000</title></use>
<rect id='aa263_symbol' height='2.5' width='2.5' x='89.2554' y='137.237' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Gly264: boxFF2200000000</title></rect>
<use id='aa263_letter' fill='#000000' x='89.7533' xlink:href='#g271' y='139.305'><title>Gly264: boxFF2200000000</title></use>
<rect id='aa264_symbol' height='2.5' width='2.5' x='89.2554' y='140.444' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Leu265: boxFF8800000000</title></rect>
<use id='aa264_letter' fill='#000000' x='89.8918' xlink:href='#g276' y='142.512'><title>Leu265: boxFF8800000000</title></use>
<circle id='aa265_symbol' r='1.6' cx='90.5054' cy='144.901' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Asp266: circFF2200FFFFFF</title></circle>
<use id='aa265_letter' fill='#000000' x='89.6904' xlink:href='#g268' y='145.718'><title>Asp266: circFF2200FFFFFF</title></use>
<circle id='aa266_symbol' r='1.6' cx='90.5054' cy='148.10799' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Ala267: circFF4400FFFFFF</title></circle>
<use id='aa266_letter' fill='#000000' x='89.75' xlink:href='#g265' y='148.925'><title>Ala267: circFF4400FFFFFF</title></use>
<circle id='aa267_symbol' r='1.6' cx='90.5054' cy='151.31499' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Met268: circFF8800000000</title></circle>
<use id='aa267_letter' fill='#000000' x='89.518' xlink:href='#g277' y='152.132'><title>Met268: circFF8800000000</title></use>
<circle id='aa268_symbol' r='1.6' cx='90.5054' cy='154.52199' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Tyr269: circAAFF00000000</title></circle>
<use id='aa268_letter' fill='#000000' x='89.75' xlink:href='#g289' y='155.339'><title>Tyr269: circAAFF00000000</title></use>
<circle id='aa269_symbol' r='1.6' cx='89.864' cy='157.72899' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Val270: circFF6600000000</title></circle>
<use id='aa269_letter' fill='#000000' x='89.1086' xlink:href='#g286' y='158.546'><title>Val270: circFF6600000000</title></use>
<text x='87.90284' y='157.33676' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>270</text><circle id='aa270_symbol' r='1.6' cx='86.6571' cy='158.37' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Ile271: circFF4400000000</title></circle>
<use id='aa270_letter' fill='#000000' x='86.3109' xlink:href='#g273' y='159.188'><title>Ile271: circFF4400000000</title></use>
<circle id='aa271_symbol' r='1.6' cx='83.450096' cy='159.012' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Met272: circFF2200000000</title></circle>
<use id='aa271_letter' fill='#000000' x='82.4628' xlink:href='#g277' y='159.829'><title>Met272: circFF2200000000</title></use>
<circle id='aa272_symbol' r='1.6' cx='80.2432' cy='159.653' fill='#ccff00' stroke='#000000' stroke-width='0.3'><title>Trp273: circCCFF00000000</title></circle>
<use id='aa272_letter' fill='#000000' x='79.1817' xlink:href='#g287' y='160.47'><title>Trp273: circCCFF00000000</title></use>
<circle id='aa273_symbol' r='1.6' cx='88.5812' cy='160.93599' fill='#eeff00' stroke='#000000' stroke-width='0.3'><title>Ile274: circEEFF00000000</title></circle>
<use id='aa273_letter' fill='#000000' x='88.2351' xlink:href='#g273' y='161.753'><title>Ile274: circEEFF00000000</title></use>
<circle id='aa274_symbol' r='1.6' cx='85.3743' cy='161.577' fill='#ffee00' stroke='#000000' stroke-width='0.3'><title>Thr275: circFFEE00000000</title></circle>
<use id='aa274_letter' fill='#000000' x='84.6093' xlink:href='#g284' y='162.395'><title>Thr275: circFFEE00000000</title></use>
<circle id='aa275_symbol' r='1.6' cx='82.1674' cy='162.219' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Tyr276: circFF4400000000</title></circle>
<use id='aa275_letter' fill='#000000' x='81.412' xlink:href='#g289' y='163.036'><title>Tyr276: circFF4400000000</title></use>
<circle id='aa276_symbol' r='1.6' cx='90.5054' cy='163.502' fill='#ccff00' stroke='#000000' stroke-width='0.3'><title>Met277: circCCFF00000000</title></circle>
<use id='aa276_letter' fill='#000000' x='89.518' xlink:href='#g277' y='164.319'><title>Met277: circCCFF00000000</title></use>
<circle id='aa277_symbol' r='1.6' cx='87.2985' cy='164.14299' fill='#ccff00' stroke='#000000' stroke-width='0.3'><title>Ala278: circCCFF00000000</title></circle>
<use id='aa277_letter' fill='#000000' x='86.5431' xlink:href='#g265' y='164.96'><title>Ala278: circCCFF00000000</title></use>
<circle id='aa278_symbol' r='1.6' cx='84.0915' cy='164.784' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Phe279: circE00000000000</title></circle>
<use id='aa278_letter' fill='#000000' x='83.4473' xlink:href='#g270' y='165.601'><title>Phe279: circE00000000000</title></use>
<circle id='aa279_symbol' r='1.6' cx='80.8846' cy='165.426' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Leu280: circFF8800000000</title></circle>
<use id='aa279_letter' fill='#000000' x='80.271' xlink:href='#g276' y='166.243'><title>Leu280: circFF8800000000</title></use>
<text x='80.492004' y='163.4649' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>280</text><circle id='aa280_symbol' r='1.6' cx='89.222595' cy='166.708' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Leu281: circFF8800000000</title></circle>
<use id='aa280_letter' fill='#000000' x='88.609' xlink:href='#g276' y='167.526'><title>Leu281: circFF8800000000</title></use>
<circle id='aa281_symbol' r='1.6' cx='86.0157' cy='167.34999' fill='#eeff00' stroke='#000000' stroke-width='0.3'><title>Val282: circEEFF00000000</title></circle>
<use id='aa281_letter' fill='#000000' x='85.2603' xlink:href='#g286' y='168.167'><title>Val282: circEEFF00000000</title></use>
<circle id='aa282_symbol' r='1.6' cx='82.8087' cy='167.991' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Phe283: circFF2200000000</title></circle>
<use id='aa282_letter' fill='#000000' x='82.1645' xlink:href='#g270' y='168.808'><title>Phe283: circFF2200000000</title></use>
<circle id='aa283_symbol' r='1.6' cx='87.9398' cy='169.915' fill='#ffee00' stroke='#000000' stroke-width='0.3'><title>Phe284: circFFEE00000000</title></circle>
<use id='aa283_letter' fill='#000000' x='87.2956' xlink:href='#g270' y='170.733'><title>Phe284: circFFEE00000000</title></use>
<circle id='aa284_symbol' r='1.6' cx='84.732895' cy='170.55699' fill='#ccff00' stroke='#000000' stroke-width='0.3'><title>Gly285: circCCFF00000000</title></circle>
<use id='aa284_letter' fill='#000000' x='83.9808' xlink:href='#g271' y='171.374'><title>Gly285: circCCFF00000000</title></use>
<circle id='aa285_symbol' r='1.6' cx='81.526' cy='171.198' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Ala286: circAAFF00000000</title></circle>
<use id='aa285_letter' fill='#000000' x='80.7706' xlink:href='#g265' y='172.015'><title>Ala286: circAAFF00000000</title></use>
<circle id='aa286_symbol' r='1.6' cx='89.864' cy='172.48099' fill='#eeff00' stroke='#000000' stroke-width='0.3'><title>Phe287: circEEFF00000000</title></circle>
<use id='aa286_letter' fill='#000000' x='89.2198' xlink:href='#g270' y='173.298'><title>Phe287: circEEFF00000000</title></use>
<circle id='aa287_symbol' r='1.6' cx='86.6571' cy='173.122' fill='#ffee00' stroke='#000000' stroke-width='0.3'><title>Phe288: circFFEE00000000</title></circle>
<use id='aa287_letter' fill='#000000' x='86.0129' xlink:href='#g270' y='173.94'><title>Phe288: circFFEE00000000</title></use>
<circle id='aa288_symbol' r='1.6' cx='83.450096' cy='173.76399' fill='#eeff00' stroke='#000000' stroke-width='0.3'><title>Ala289: circEEFF00000000</title></circle>
<use id='aa288_letter' fill='#000000' x='82.6948' xlink:href='#g265' y='174.581'><title>Ala289: circEEFF00000000</title></use>
<rect id='aa289_symbol' height='2.5' width='2.5' x='78.9932' y='173.155' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Val290: boxAAFF00000000</title></rect>
<use id='aa289_letter' fill='#000000' x='79.4878' xlink:href='#g286' y='175.222'><title>Val290: boxAAFF00000000</title></use>
<text x='79.85119' y='172.44379' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>290</text><rect id='aa290_symbol' height='2.5' width='2.5' x='78.3518' y='176.362' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Trp291: boxFF4400000000</title></rect>
<use id='aa290_letter' fill='#000000' x='78.5403' xlink:href='#g287' y='178.429'><title>Trp291: boxFF4400000000</title></use>
<rect id='aa291_symbol' height='2.5' width='2.5' x='78.3518' y='179.569' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Cys292: boxFF6600000000</title></rect>
<use id='aa291_letter' fill='#000000' x='78.8803' xlink:href='#g267' y='181.636'><title>Cys292: boxFF6600000000</title></use>
<rect id='aa292_symbol' height='2.5' width='2.5' x='78.3518' y='182.776' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Tyr293: boxFF4400000000</title></rect>
<use id='aa292_letter' fill='#000000' x='78.8464' xlink:href='#g289' y='184.843'><title>Tyr293: boxFF4400000000</title></use>
<rect id='aa293_symbol' height='2.5' width='2.5' x='78.3518' y='185.98299' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Arg294: boxE00000000000</title></rect>
<use id='aa293_letter' fill='#000000' x='78.8722' xlink:href='#g282' y='188.05'><title>Arg294: boxE00000000000</title></use>
<rect id='aa294_symbol' height='2.5' width='2.5' x='78.3518' y='189.18999' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Lys295: boxFF4400000000</title></rect>
<use id='aa294_letter' fill='#000000' x='78.8158' xlink:href='#g275' y='191.257'><title>Lys295: boxFF4400000000</title></use>
<rect id='aa295_symbol' height='2.5' width='2.5' x='78.3518' y='192.39699' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Arg296: boxFF4400000000</title></rect>
<use id='aa295_letter' fill='#000000' x='78.8722' xlink:href='#g282' y='194.464'><title>Arg296: boxFF4400000000</title></use>
<circle id='aa296_symbol' r='1.6' cx='79.6018' cy='196.85399' fill='#ccff00' stroke='#ffffff' stroke-width='0.3'><title>Tyr297: circCCFF00FFFFFF</title></circle>
<use id='aa296_letter' fill='#000000' x='78.8464' xlink:href='#g289' y='197.671'><title>Tyr297: circCCFF00FFFFFF</title></use>
<circle id='aa297_symbol' r='1.6' cx='79.6018' cy='200.06099' fill='#ff6600' stroke='#ffffff' stroke-width='0.3'><title>Phe298: circFF6600FFFFFF</title></circle>
<use id='aa297_letter' fill='#000000' x='78.9576' xlink:href='#g270' y='200.878'><title>Phe298: circFF6600FFFFFF</title></use>
<circle id='aa298_symbol' r='1.6' cx='79.6018' cy='203.26799' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Val299: circAAFF00FFFFFF</title></circle>
<use id='aa298_letter' fill='#000000' x='78.8464' xlink:href='#g286' y='204.085'><title>Val299: circAAFF00FFFFFF</title></use>
<circle id='aa299_symbol' r='1.6' cx='79.6018' cy='206.474' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Ser300: circE00000FFFFFF</title></circle>
<use id='aa299_letter' fill='#000000' x='78.9721' xlink:href='#g283' y='207.292'><title>Ser300: circE00000FFFFFF</title></use>
<text x='77.6018' y='206.474' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>300</text><circle id='aa300_symbol' r='1.6' cx='79.6018' cy='209.681' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Glu301: circE00000FFFFFF</title></circle>
<use id='aa300_letter' fill='#000000' x='78.927' xlink:href='#g269' y='210.499'><title>Glu301: circE00000FFFFFF</title></use>
<circle id='aa301_symbol' r='1.6' cx='79.6018' cy='212.888' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Tyr302: circFF2200FFFFFF</title></circle>
<use id='aa301_letter' fill='#000000' x='78.8464' xlink:href='#g289' y='213.706'><title>Tyr302: circFF2200FFFFFF</title></use>
<circle id='aa302_symbol' r='1.6' cx='79.6018' cy='216.095' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Thr303: circFF4400FFFFFF</title></circle>
<use id='aa302_letter' fill='#000000' x='78.8368' xlink:href='#g284' y='216.913'><title>Thr303: circFF4400FFFFFF</title></use>
<circle id='aa303_symbol' r='1.6' cx='79.6018' cy='219.30199' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Pro304: circE00000FFFFFF</title></circle>
<use id='aa303_letter' fill='#000000' x='78.8787' xlink:href='#g280' y='220.119'><title>Pro304: circE00000FFFFFF</title></use>
<circle id='aa304_symbol' r='1.6' cx='79.6018' cy='222.50899' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Ile305: circE00000FFFFFF</title></circle>
<use id='aa304_letter' fill='#000000' x='79.2556' xlink:href='#g273' y='223.326'><title>Ile305: circE00000FFFFFF</title></use>
<circle id='aa305_symbol' r='1.6' cx='79.6018' cy='225.71599' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Asp306: circFF2200FFFFFF</title></circle>
<use id='aa305_letter' fill='#000000' x='78.7868' xlink:href='#g268' y='226.533'><title>Asp306: circFF2200FFFFFF</title></use>
<circle id='aa306_symbol' r='1.6' cx='79.6018' cy='228.92299' fill='#ff6600' stroke='#ffffff' stroke-width='0.3'><title>Ser307: circFF6600FFFFFF</title></circle>
<use id='aa306_letter' fill='#000000' x='78.9721' xlink:href='#g283' y='229.74'><title>Ser307: circFF6600FFFFFF</title></use>
<circle id='aa307_symbol' r='1.6' cx='79.6018' cy='232.12999' fill='#ff8800' stroke='#ffffff' stroke-width='0.3'><title>Asn308: circFF8800FFFFFF</title></circle>
<use id='aa307_letter' fill='#000000' x='78.7981' xlink:href='#g278' y='232.947'><title>Asn308: circFF8800FFFFFF</title></use>
<circle id='aa308_symbol' r='1.6' cx='79.6018' cy='235.33699' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Ile309: circAAFF00FFFFFF</title></circle>
<use id='aa308_letter' fill='#000000' x='79.2556' xlink:href='#g273' y='236.154'><title>Ile309: circAAFF00FFFFFF</title></use>
<circle id='aa309_symbol' r='1.6' cx='79.6018' cy='238.54399' fill='#ffaa00' stroke='#ffffff' stroke-width='0.3'><title>Ala310: circFFAA00FFFFFF</title></circle>
<use id='aa309_letter' fill='#000000' x='78.8464' xlink:href='#g265' y='239.361'><title>Ala310: circFFAA00FFFFFF</title></use>
<text x='77.6018' y='238.54399' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>310</text><circle id='aa310_symbol' r='1.6' cx='79.6018' cy='241.75099' fill='#ffaa00' stroke='#ffffff' stroke-width='0.3'><title>Phe311: circFFAA00FFFFFF</title></circle>
<use id='aa310_letter' fill='#000000' x='78.9576' xlink:href='#g270' y='242.568'><title>Phe311: circFFAA00FFFFFF</title></use>
<circle id='aa311_symbol' r='1.6' cx='79.6018' cy='244.958' fill='#ffcc00' stroke='#ffffff' stroke-width='0.3'><title>Ser312: circFFCC00FFFFFF</title></circle>
<use id='aa311_letter' fill='#000000' x='78.9721' xlink:href='#g283' y='245.775'><title>Ser312: circFFCC00FFFFFF</title></use>
<circle id='aa312_symbol' r='1.6' cx='79.6018' cy='248.165' fill='#ffaa00' stroke='#ffffff' stroke-width='0.3'><title>Val313: circFFAA00FFFFFF</title></circle>
<use id='aa312_letter' fill='#000000' x='78.8464' xlink:href='#g286' y='248.982'><title>Val313: circFFAA00FFFFFF</title></use>
<circle id='aa313_symbol' r='1.6' cx='79.6018' cy='251.372' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Asn314: circFF4400FFFFFF</title></circle>
<use id='aa313_letter' fill='#000000' x='78.7981' xlink:href='#g278' y='252.189'><title>Asn314: circFF4400FFFFFF</title></use>
<circle id='aa314_symbol' r='1.6' cx='79.6018' cy='254.57898' fill='#ff8800' stroke='#ffffff' stroke-width='0.3'><title>Ala315: circFF8800FFFFFF</title></circle>
<use id='aa314_letter' fill='#000000' x='78.8464' xlink:href='#g265' y='255.396'><title>Ala315: circFF8800FFFFFF</title></use>
<circle id='aa315_symbol' r='1.6' cx='79.6018' cy='257.78598' fill='#55ff00' stroke='#ffffff' stroke-width='0.3'><title>Ser316: circ55FF00FFFFFF</title></circle>
<use id='aa315_letter' fill='#000000' x='78.9721' xlink:href='#g283' y='258.603'><title>Ser316: circ55FF00FFFFFF</title></use>
<circle id='aa316_symbol' r='1.6' cx='79.6018' cy='260.992' fill='#55ff00' stroke='#ffffff' stroke-width='0.3'><title>Asp317: circ55FF00FFFFFF</title></circle>
<use id='aa316_letter' fill='#000000' x='78.7868' xlink:href='#g268' y='261.81'><title>Asp317: circ55FF00FFFFFF</title></use>
<circle id='aa317_symbol' r='1.6' cx='81.526' cy='263.55798' fill='#55ff00' stroke='#ffffff' stroke-width='0.3'><title>Lys318: circ55FF00FFFFFF</title></circle>
<use id='aa317_letter' fill='#000000' x='80.74' xlink:href='#g275' y='264.375'><title>Lys318: circ55FF00FFFFFF</title></use>
<circle id='aa318_symbol' r='1.6' cx='84.0915' cy='265.482' fill='#ffee00' stroke='#ffffff' stroke-width='0.3'><title>Gly319: circFFEE00FFFFFF</title></circle>
<use id='aa318_letter' fill='#000000' x='83.3394' xlink:href='#g271' y='266.299'><title>Gly319: circFFEE00FFFFFF</title></use>
<circle id='aa319_symbol' r='1.6' cx='87.2985' cy='266.124' fill='#ccff00' stroke='#ffffff' stroke-width='0.3'><title>Glu320: circCCFF00FFFFFF</title></circle>
<use id='aa319_letter' fill='#000000' x='86.6236' xlink:href='#g269' y='266.941'><title>Glu320: circCCFF00FFFFFF</title></use>
<text x='86.905914' y='268.08508' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='end'>320</text><circle id='aa320_symbol' r='1.6' cx='90.5054' cy='266.124' fill='#ffee00' stroke='#ffffff' stroke-width='0.3'><title>Ala321: circFFEE00FFFFFF</title></circle>
<use id='aa320_letter' fill='#000000' x='89.75' xlink:href='#g265' y='266.941'><title>Ala321: circFFEE00FFFFFF</title></use>
<circle id='aa321_symbol' r='1.6' cx='93.712296' cy='265.482' fill='#ccff00' stroke='#ffffff' stroke-width='0.3'><title>Ser322: circCCFF00FFFFFF</title></circle>
<use id='aa321_letter' fill='#000000' x='93.0826' xlink:href='#g283' y='266.299'><title>Ser322: circCCFF00FFFFFF</title></use>
<circle id='aa322_symbol' r='1.6' cx='96.2779' cy='263.55798' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Cys323: circFF4400FFFFFF</title></circle>
<use id='aa322_letter' fill='#000000' x='95.5564' xlink:href='#g267' y='264.375'><title>Cys323: circFF4400FFFFFF</title></use>
<circle id='aa323_symbol' r='1.6' cx='98.202095' cy='260.992' fill='#eeff00' stroke='#ffffff' stroke-width='0.3'><title>Cys324: circEEFF00FFFFFF</title></circle>
<use id='aa323_letter' fill='#000000' x='97.4805' xlink:href='#g267' y='261.81'><title>Cys324: circEEFF00FFFFFF</title></use>
<circle id='aa324_symbol' r='1.6' cx='98.202095' cy='257.78598' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Asp325: circFF4400FFFFFF</title></circle>
<use id='aa324_letter' fill='#000000' x='97.3871' xlink:href='#g268' y='258.603'><title>Asp325: circFF4400FFFFFF</title></use>
<circle id='aa325_symbol' r='1.6' cx='98.202095' cy='254.57898' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Pro326: circAAFF00FFFFFF</title></circle>
<use id='aa325_letter' fill='#000000' x='97.4789' xlink:href='#g280' y='255.396'><title>Pro326: circAAFF00FFFFFF</title></use>
<circle id='aa326_symbol' r='1.6' cx='98.202095' cy='251.372' fill='#ccff00' stroke='#ffffff' stroke-width='0.3'><title>Val327: circCCFF00FFFFFF</title></circle>
<use id='aa326_letter' fill='#000000' x='97.4467' xlink:href='#g286' y='252.189'><title>Val327: circCCFF00FFFFFF</title></use>
<circle id='aa327_symbol' r='1.6' cx='98.202095' cy='248.165' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Ser328: circFF6600000000</title></circle>
<use id='aa327_letter' fill='#000000' x='97.5724' xlink:href='#g283' y='248.982'><title>Ser328: circFF6600000000</title></use>
<circle id='aa328_symbol' r='1.6' cx='98.202095' cy='244.958' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Ala329: circFF6600000000</title></circle>
<use id='aa328_letter' fill='#000000' x='97.4467' xlink:href='#g265' y='245.775'><title>Ala329: circFF6600000000</title></use>
<circle id='aa329_symbol' r='1.6' cx='98.202095' cy='241.75099' fill='#00ff00' stroke='#000000' stroke-width='0.3'><title>Ala330: circ00FF00000000</title></circle>
<use id='aa329_letter' fill='#000000' x='97.4467' xlink:href='#g265' y='242.568'><title>Ala330: circ00FF00000000</title></use>
<text x='100.202095' y='241.75099' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>330</text><circle id='aa330_symbol' r='1.6' cx='98.202095' cy='238.54399' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Phe331: circFF8800000000</title></circle>
<use id='aa330_letter' fill='#000000' x='97.5578' xlink:href='#g270' y='239.361'><title>Phe331: circFF8800000000</title></use>
<circle id='aa331_symbol' r='1.6' cx='98.202095' cy='235.33699' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Glu332: circFF2200000000</title></circle>
<use id='aa331_letter' fill='#000000' x='97.5272' xlink:href='#g269' y='236.154'><title>Glu332: circFF2200000000</title></use>
<circle id='aa332_symbol' r='1.6' cx='98.202095' cy='232.12999' fill='#55ff00' stroke='#000000' stroke-width='0.3'><title>Gly333: circ55FF00000000</title></circle>
<use id='aa332_letter' fill='#000000' x='97.4499' xlink:href='#g271' y='232.947'><title>Gly333: circ55FF00000000</title></use>
<circle id='aa333_symbol' r='1.6' cx='98.202095' cy='228.92299' fill='#55ff00' stroke='#000000' stroke-width='0.3'><title>Cys334: circ55FF00000000</title></circle>
<use id='aa333_letter' fill='#000000' x='97.4805' xlink:href='#g267' y='229.74'><title>Cys334: circ55FF00000000</title></use>
<circle id='aa334_symbol' r='1.6' cx='98.202095' cy='225.71599' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Leu335: circFF2200000000</title></circle>
<use id='aa334_letter' fill='#000000' x='97.5885' xlink:href='#g276' y='226.533'><title>Leu335: circFF2200000000</title></use>
<circle id='aa335_symbol' r='1.6' cx='98.202095' cy='222.50899' fill='#ffee00' stroke='#000000' stroke-width='0.3'><title>Arg336: circFFEE00000000</title></circle>
<use id='aa335_letter' fill='#000000' x='97.4725' xlink:href='#g282' y='223.326'><title>Arg336: circFFEE00000000</title></use>
<circle id='aa336_symbol' r='1.6' cx='98.202095' cy='219.30199' fill='#00ff00' stroke='#000000' stroke-width='0.3'><title>Arg337: circ00FF00000000</title></circle>
<use id='aa336_letter' fill='#000000' x='97.4725' xlink:href='#g282' y='220.119'><title>Arg337: circ00FF00000000</title></use>
<circle id='aa337_symbol' r='1.6' cx='98.202095' cy='216.095' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Leu338: circAAFF00000000</title></circle>
<use id='aa337_letter' fill='#000000' x='97.5885' xlink:href='#g276' y='216.913'><title>Leu338: circAAFF00000000</title></use>
<circle id='aa338_symbol' r='1.6' cx='98.202095' cy='212.888' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Phe339: circE00000000000</title></circle>
<use id='aa338_letter' fill='#000000' x='97.5578' xlink:href='#g270' y='213.706'><title>Phe339: circE00000000000</title></use>
<circle id='aa339_symbol' r='1.6' cx='98.202095' cy='209.681' fill='#aaff00' stroke='#000000' stroke-width='0.3'><title>Thr340: circAAFF00000000</title></circle>
<use id='aa339_letter' fill='#000000' x='97.437' xlink:href='#g284' y='210.499'><title>Thr340: circAAFF00000000</title></use>
<text x='100.202095' y='209.681' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>340</text><circle id='aa340_symbol' r='1.6' cx='98.202095' cy='206.474' fill='#00ff00' stroke='#000000' stroke-width='0.3'><title>Arg341: circ00FF00000000</title></circle>
<use id='aa340_letter' fill='#000000' x='97.4725' xlink:href='#g282' y='207.292'><title>Arg341: circ00FF00000000</title></use>
<circle id='aa341_symbol' r='1.6' cx='98.202095' cy='203.26799' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Trp342: circE00000000000</title></circle>
<use id='aa341_letter' fill='#000000' x='97.1406' xlink:href='#g287' y='204.085'><title>Trp342: circE00000000000</title></use>
<circle id='aa342_symbol' r='1.6' cx='98.202095' cy='200.06099' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Gly343: circE00000FFFFFF</title></circle>
<use id='aa342_letter' fill='#000000' x='97.4499' xlink:href='#g271' y='200.878'><title>Gly343: circE00000FFFFFF</title></use>
<circle id='aa343_symbol' r='1.6' cx='98.202095' cy='196.85399' fill='#55ff00' stroke='#ffffff' stroke-width='0.3'><title>Ser344: circ55FF00FFFFFF</title></circle>
<use id='aa343_letter' fill='#000000' x='97.5724' xlink:href='#g283' y='197.671'><title>Ser344: circ55FF00FFFFFF</title></use>
<circle id='aa344_symbol' r='1.6' cx='98.202095' cy='193.64699' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Phe345: circFF4400FFFFFF</title></circle>
<use id='aa344_letter' fill='#000000' x='97.5578' xlink:href='#g270' y='194.464'><title>Phe345: circFF4400FFFFFF</title></use>
<circle id='aa345_symbol' r='1.6' cx='98.202095' cy='190.43999' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Cys346: circE00000FFFFFF</title></circle>
<use id='aa345_letter' fill='#000000' x='97.4805' xlink:href='#g267' y='191.257'><title>Cys346: circE00000FFFFFF</title></use>
<circle id='aa346_symbol' r='1.6' cx='98.202095' cy='187.23299' fill='#ffaa00' stroke='#ffffff' stroke-width='0.3'><title>Val347: circFFAA00FFFFFF</title></circle>
<use id='aa346_letter' fill='#000000' x='97.4467' xlink:href='#g286' y='188.05'><title>Val347: circFFAA00FFFFFF</title></use>
<circle id='aa347_symbol' r='1.6' cx='98.202095' cy='184.026' fill='#ff6600' stroke='#ffffff' stroke-width='0.3'><title>Arg348: circFF6600FFFFFF</title></circle>
<use id='aa347_letter' fill='#000000' x='97.4725' xlink:href='#g282' y='184.843'><title>Arg348: circFF6600FFFFFF</title></use>
<circle id='aa348_symbol' r='1.6' cx='98.202095' cy='180.819' fill='#ffee00' stroke='#ffffff' stroke-width='0.3'><title>Asn349: circFFEE00FFFFFF</title></circle>
<use id='aa348_letter' fill='#000000' x='97.3983' xlink:href='#g278' y='181.636'><title>Asn349: circFFEE00FFFFFF</title></use>
<circle id='aa349_symbol' r='1.6' cx='98.202095' cy='177.612' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Pro350: circE00000FFFFFF</title></circle>
<use id='aa349_letter' fill='#000000' x='97.4789' xlink:href='#g280' y='178.429'><title>Pro350: circE00000FFFFFF</title></use>
<text x='100.202095' y='177.612' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>350</text><circle id='aa350_symbol' r='1.6' cx='98.8434' cy='174.405' fill='#55ff00' stroke='#ffffff' stroke-width='0.3'><title>Gly351: circ55FF00FFFFFF</title></circle>
<use id='aa350_letter' fill='#000000' x='98.0913' xlink:href='#g271' y='175.222'><title>Gly351: circ55FF00FFFFFF</title></use>
<circle id='aa351_symbol' r='1.6' cx='102.0504' cy='173.76399' fill='#00ff00' stroke='#000000' stroke-width='0.3'><title>Cys352: circ00FF00000000</title></circle>
<use id='aa351_letter' fill='#000000' x='101.329' xlink:href='#g267' y='174.581'><title>Cys352: circ00FF00000000</title></use>
<circle id='aa352_symbol' r='1.6' cx='105.256996' cy='173.122' fill='#ff2200' stroke='#000000' stroke-width='0.3'><title>Val353: circFF2200000000</title></circle>
<use id='aa352_letter' fill='#000000' x='104.502' xlink:href='#g286' y='173.94'><title>Val353: circFF2200000000</title></use>
<circle id='aa353_symbol' r='1.6' cx='108.464' cy='172.48099' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Ile354: circFF6600000000</title></circle>
<use id='aa353_letter' fill='#000000' x='108.118' xlink:href='#g273' y='173.298'><title>Ile354: circFF6600000000</title></use>
<circle id='aa354_symbol' r='1.6' cx='100.1262' cy='171.198' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Phe355: circFF8800000000</title></circle>
<use id='aa354_letter' fill='#000000' x='99.482' xlink:href='#g270' y='172.015'><title>Phe355: circFF8800000000</title></use>
<circle id='aa355_symbol' r='1.6' cx='103.333' cy='170.55699' fill='#eeff00' stroke='#000000' stroke-width='0.3'><title>Phe356: circEEFF00000000</title></circle>
<use id='aa355_letter' fill='#000000' x='102.689' xlink:href='#g270' y='171.374'><title>Phe356: circEEFF00000000</title></use>
<circle id='aa356_symbol' r='1.6' cx='106.54' cy='169.915' fill='#ffee00' stroke='#000000' stroke-width='0.3'><title>Ser357: circFFEE00000000</title></circle>
<use id='aa356_letter' fill='#000000' x='105.91' xlink:href='#g283' y='170.733'><title>Ser357: circFFEE00000000</title></use>
<circle id='aa357_symbol' r='1.6' cx='98.202095' cy='168.633' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Leu358: circFF6600000000</title></circle>
<use id='aa357_letter' fill='#000000' x='97.5885' xlink:href='#g276' y='169.45'><title>Leu358: circFF6600000000</title></use>
<circle id='aa358_symbol' r='1.6' cx='101.409' cy='167.991' fill='#eeff00' stroke='#000000' stroke-width='0.3'><title>Val359: circEEFF00000000</title></circle>
<use id='aa358_letter' fill='#000000' x='100.654' xlink:href='#g286' y='168.808'><title>Val359: circEEFF00000000</title></use>
<circle id='aa359_symbol' r='1.6' cx='104.616' cy='167.34999' fill='#ff8800' stroke='#000000' stroke-width='0.3'><title>Phe360: circFF8800000000</title></circle>
<use id='aa359_letter' fill='#000000' x='103.972' xlink:href='#g270' y='168.167'><title>Phe360: circFF8800000000</title></use>
<text x='105.007996' y='169.3112' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>360</text><circle id='aa360_symbol' r='1.6' cx='107.823' cy='166.708' fill='#ff6600' stroke='#000000' stroke-width='0.3'><title>Ile361: circFF6600000000</title></circle>
<use id='aa360_letter' fill='#000000' x='107.477' xlink:href='#g273' y='167.526'><title>Ile361: circFF6600000000</title></use>
<circle id='aa361_symbol' r='1.6' cx='99.4848' cy='165.426' fill='#ffee00' stroke='#000000' stroke-width='0.3'><title>Thr362: circFFEE00000000</title></circle>
<use id='aa361_letter' fill='#000000' x='98.7198' xlink:href='#g284' y='166.243'><title>Thr362: circFFEE00000000</title></use>
<circle id='aa362_symbol' r='1.6' cx='102.692' cy='164.784' fill='#eeff00' stroke='#000000' stroke-width='0.3'><title>Ala363: circEEFF00000000</title></circle>
<use id='aa362_letter' fill='#000000' x='101.936' xlink:href='#g265' y='165.601'><title>Ala363: circEEFF00000000</title></use>
<circle id='aa363_symbol' r='1.6' cx='105.899' cy='164.14299' fill='#ffaa00' stroke='#000000' stroke-width='0.3'><title>Cys364: circFFAA00000000</title></circle>
<use id='aa363_letter' fill='#000000' x='105.177' xlink:href='#g267' y='164.96'><title>Cys364: circFFAA00000000</title></use>
<circle id='aa364_symbol' r='1.6' cx='100.7676' cy='162.219' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Ser365: circFF4400000000</title></circle>
<use id='aa364_letter' fill='#000000' x='100.138' xlink:href='#g283' y='163.036'><title>Ser365: circFF4400000000</title></use>
<circle id='aa365_symbol' r='1.6' cx='103.975' cy='161.577' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Ser366: circAAFF00FFFFFF</title></circle>
<use id='aa365_letter' fill='#000000' x='103.345' xlink:href='#g283' y='162.395'><title>Ser366: circAAFF00FFFFFF</title></use>
<circle id='aa366_symbol' r='1.6' cx='107.181' cy='160.93599' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Gly367: circE00000FFFFFF</title></circle>
<use id='aa366_letter' fill='#000000' x='106.429' xlink:href='#g271' y='161.753'><title>Gly367: circE00000FFFFFF</title></use>
<circle id='aa367_symbol' r='1.6' cx='98.8434' cy='159.653' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Leu368: circFF4400FFFFFF</title></circle>
<use id='aa367_letter' fill='#000000' x='98.2299' xlink:href='#g276' y='160.47'><title>Leu368: circFF4400FFFFFF</title></use>
<circle id='aa368_symbol' r='1.6' cx='102.0504' cy='159.012' fill='#aaff00' stroke='#ffffff' stroke-width='0.3'><title>Val369: circAAFF00FFFFFF</title></circle>
<use id='aa368_letter' fill='#000000' x='101.295' xlink:href='#g286' y='159.829'><title>Val369: circAAFF00FFFFFF</title></use>
<circle id='aa369_symbol' r='1.6' cx='105.256996' cy='158.37' fill='#ff6600' stroke='#ffffff' stroke-width='0.3'><title>Phe370: circFF6600FFFFFF</title></circle>
<use id='aa369_letter' fill='#000000' x='104.613' xlink:href='#g270' y='159.188'><title>Phe370: circFF6600FFFFFF</title></use>
<text x='105.64963' y='160.33107' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>370</text><circle id='aa370_symbol' r='1.6' cx='108.464' cy='157.72899' fill='#ffcc00' stroke='#ffffff' stroke-width='0.3'><title>Val371: circFFCC00FFFFFF</title></circle>
<use id='aa370_letter' fill='#000000' x='107.709' xlink:href='#g286' y='158.546'><title>Val371: circFFCC00FFFFFF</title></use>
<rect id='aa371_symbol' height='2.5' width='2.5' x='107.855995' y='153.27199' fill='#ccff00' stroke='#000000' stroke-width='0.3'><title>Arg372: boxCCFF00000000</title></rect>
<use id='aa371_letter' fill='#000000' x='108.376' xlink:href='#g282' y='155.339'><title>Arg372: boxCCFF00000000</title></use>
<rect id='aa372_symbol' height='2.5' width='2.5' x='107.855995' y='150.06499' fill='#ff4400' stroke='#000000' stroke-width='0.3'><title>Val373: boxFF4400000000</title></rect>
<use id='aa372_letter' fill='#000000' x='108.35' xlink:href='#g286' y='152.132'><title>Val373: boxFF4400000000</title></use>
<circle id='aa373_symbol' r='1.6' cx='109.105995' cy='148.10799' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Thr374: circFF2200FFFFFF</title></circle>
<use id='aa373_letter' fill='#000000' x='108.341' xlink:href='#g284' y='148.925'><title>Thr374: circFF2200FFFFFF</title></use>
<circle id='aa374_symbol' r='1.6' cx='109.105995' cy='144.901' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Thr375: circE00000FFFFFF</title></circle>
<use id='aa374_letter' fill='#000000' x='108.341' xlink:href='#g284' y='145.718'><title>Thr375: circE00000FFFFFF</title></use>
<circle id='aa375_symbol' r='1.6' cx='109.105995' cy='141.694' fill='#ff4400' stroke='#ffffff' stroke-width='0.3'><title>Asn376: circFF4400FFFFFF</title></circle>
<use id='aa375_letter' fill='#000000' x='108.302' xlink:href='#g278' y='142.512'><title>Asn376: circFF4400FFFFFF</title></use>
<circle id='aa376_symbol' r='1.6' cx='109.105995' cy='138.487' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Pro377: circE00000FFFFFF</title></circle>
<use id='aa376_letter' fill='#000000' x='108.383' xlink:href='#g280' y='139.305'><title>Pro377: circE00000FFFFFF</title></use>
<circle id='aa377_symbol' r='1.6' cx='109.105995' cy='135.28' fill='#ff2200' stroke='#ffffff' stroke-width='0.3'><title>Val378: circFF2200FFFFFF</title></circle>
<use id='aa377_letter' fill='#000000' x='108.35' xlink:href='#g286' y='136.098'><title>Val378: circFF2200FFFFFF</title></use>
<circle id='aa378_symbol' r='1.6' cx='109.105995' cy='132.073' fill='#ffaa00' stroke='#ffffff' stroke-width='0.3'><title>Asp379: circFFAA00FFFFFF</title></circle>
<use id='aa378_letter' fill='#000000' x='108.291' xlink:href='#g268' y='132.891'><title>Asp379: circFFAA00FFFFFF</title></use>
<circle id='aa379_symbol' r='1.6' cx='109.105995' cy='128.86699' fill='#e00000' stroke='#ffffff' stroke-width='0.3'><title>Leu380: circE00000FFFFFF</title></circle>
<use id='aa379_letter' fill='#000000' x='108.492' xlink:href='#g276' y='129.684'><title>Leu380: circE00000FFFFFF</title></use>
<text x='111.105995' y='128.86699' dy='0.7' font-family='sans-serif' font-size='1.7' fill='black' text-anchor='start'>380</text><rect id='aa380_symbol' height='2.5' width='2.5' x='107.855995' y='124.41' fill='#e00000' stroke='#000000' stroke-width='0.3'><title>Trp381: boxE00000000000</title></rect>
<use id='aa380_letter' fill='#000000' x='108.044' xlink:href='#g287' y='126.477'><title>Trp381: boxE00000000000</title></use>