- How can the skeleton of a dinosaur remain intact after millions of years?
- I need to give someone an incurable disease that they would slowly deteriorate from without proper medication. What would be a good choice?
- Has any ancient DNA ever been recovered?
- What are some interesting examples of different strains/mutations/variations of the same disease (e.g., cancer, viral infections) that are related to ethnicity or race?
- What makes influenza airborne and Ebola not airborne?
- Do researchers/scientists find reading scientific papers exciting?
- What is a layman's explanation of the 2014 Nobel Prize in Chemistry?
- How do babies sleep in the womb?
- Why do humans not walk on four legs?
- How frequently are 'new' deadly viruses discovered?
- Are there species of fungi that have more than two sexes?
- Why do we have DNAse on our skin?
- Why did humans lose the ability to make Vitamin C?
- Why are trans-unsaturated fatty acids worse for us than, say, saturated fatty acids?
- What are tmRNAs?
- How does cholesterol affect the structure of lipid bilayers?
- Is Western blot a truly reliable lab method? Are there any better alternatives?
- What is the most contagious disease on earth?
- Why does evolution have diverse paces and tempos?
- Do chaperone proteins assist in the folding of proteins only or do they assist in assembly of other macromolecules too?
- There are a lot of different amino acids in different types of organisms. But why are only 20 well-known acids proteinogenic?
- What is the physical mechanism by which proteins travel through the Golgi apparatus?
- What makes prion fibrils vulnerable to breaking, and how do they ultimately break?
- How does higher GC content induce secondary structure in nucleic acids?
- Does having a beta sheet make a protein more prone to forming aggregates?
- How unique do the amino acids responsible for a molecule's binding site have to be?
- How does hydration level affect the conformation that DNA adopts?
- How closely should an experiment copy the original in order to be a replication?
- From a biochemical perspective, what happens when your hair gets greasy?
- Can lysozyme degrade the beta 1-4 glycosidic linkages in cellulose as it does in case for peptidoglycan?
- How can neurons be so slow and yet we are so smart?
- Why don't viruses evolve to protect rather than harm their hosts?
- I want to sequence a novel animal genome. How can I verify whether or not it has already been sequenced and made public/open source?
- What-are-some-possible-ways-to-cure-Ebola-in-the-future
- How does quorum sensing work?
- Why is blocking mitochondrial fission an effective treatment for Parkinson's?
- How are Reactive Oxygen Species produced physiologically in cells?
- What is the meaning of the 28S/18s ribosomal ratio?
- What are some good ideas for interesting physics-related simulations to code as a side project?
- What frequencies of sunlight hitting our skin result in our bodies' manufacture of Vitamin D?
- Is so-called "junk" DNA really useless?
- Why haven't any animals evolved wheels for locomotion?
- Does anyone really believe in the evolutional sequence of algae, fish, bird, mammal, human?
- Does a gene's location in the nucleus matter?
- What's the difference between epigenetics and Lamarckism?
- Why does life use a quaternary system (A, T, G, C) to encode information instead of a binary system?
- How does one physically interpret the different diffraction patterns between A-DNA and B-DNA?
- How does evolution work?
- How do histones control gene expression?
- If the earth's rotation was different than 24 hours, would the human body and sleep cycle have evolved differently?
- What are some good introductory papers on GWAS?
- Quan Gan's answer to Does glutamate inhibit GABA?
- Quan Gan's answer to What controls lateral diffusion of transmembrane proteins?
- Quan Gan's answer to In neuroscience, we read a lot about the reduction in the size of the cortex or hippocampus or some other brain area. What is the meaning of this reduced size?
- What is protein threading and how does it work?
- How do cells make sure they have all 23 pairs of chromosomes before undergoing mitosis? What is the fail-safe to ensure all genetic information is transferred?
- What do ATP-binding cassette transporters do?
- Is there any difference in the base-stacking interactions between purine-purine, pyrimidine-pyrimidine, and purine-pyrimidine sets in double-stranded DNA?
- Why do most chromosomal aberrations occur in the acrocentric region?
- What are the downsides of excess heat shock response activation?
- What are some artificial organelles that can be synthesized?
- How are olfactory receptor genes expressed, and what mechanism ensures that only one receptor is expressed for each cell?
- What are the contributions of the spermatozoon's cytoplasm to the new zygote?
- Can a mutation be both a loss-of-function and a gain-of-function mutation at the same time?
- If our planet had two moons, how different would the evolution of our species be?
- Are there reliable methods for predicting the likely crystallization symmetry/symmetries of proteins?
- What happens in a chamber of a microfluidic chip?
- Why is it important to create a virtual cell?
- How do optical tweezers work?
- How did telomeres evolve?
- Why does the Myc gene/protein decrease longevity and healthspan?
- Do genes in the X-inactivated chromosome have lower mutation rates than genes in the X-activated chromosome?
- How do viral capsids assimilate specific proteins inherent to the virus from the myriad of proteins present in the cell?
- What is it like to work with Chlamydomonas as a model organism?
- A common trope in sci-fi romance is: "some bio-weapon" killed all our females and therefore we must come to earth to find women". Setting aside the question of alien/human compatibility and other logistical concerns, how possible is it to design a virus to kill off one sex and it succeeding?
- Alexander Greben's answer to What is the evolutionary history of GPCRs?
- What determines whether or not a drug (or chemical) causes curvature stress when it accumulates in the cell membrane?
- What are some interesting anthropomorphisms of biological phenomena?
- What is protein threading and how does it work?
- What is the function of the transferrin receptor in the blood-brain barrier?
- What are the downsides of JAK inhibitors?
- How have researchers confirmed the difference between a polyproline helical structure and a random coil using circular dichroism?
- What are some interesting things about centrioles and centrosomes?
- What are some unsolved problems in our understanding of human embryogenesis?
- How are most SNPs discovered and characterized?
- How does Toxoplasma gondii invade host cells?
- Who came up with the idea of using radioisotopes with mass spectrometry?
- How were protein motifs first discovered?
- How do cells make sure they have all 23 pairs of chromosomes before undergoing mitosis? What is the fail-safe to ensure all genetic information is transferred?
- What do ATP-binding cassette transporters do?
- Is there any difference in the base-stacking interactions between purine-purine, pyrimidine-pyrimidine, and purine-pyrimidine sets in double-stranded DNA?
- Why do most chromosomal aberrations occur in the acrocentric region?
- What are the downsides of excess heat shock response activation?
- What are some artificial organelles that can be synthesized?
- How are olfactory receptor genes expressed, and what mechanism ensures that only one receptor is expressed for each cell?
- What are the contributions of the spermatozoon's cytoplasm to the new zygote?
- Can a mutation be both a loss-of-function and a gain-of-function mutation at the same time?
- If our planet had two moons, how different would the evolution of our species be?
- How does Cre-Lox recombination work?
- Why is the cyclic structure of glucose 6-membered?
- Why do proteins fold?
- How does the sweet taste receptor work?
- Jens Mowatt's answer to What are the individual parts of the brain made out of on the cellular level?
- Jens Mowatt's answer to How do microglia differ from macrophages outside the nervous system?
- Jens Mowatt's answer to What do scientists know about the nervous systems of the simplest creatures?
- Introducing QOTWs.
- What is the hydrophobic effect, and what are the difficulties in relating a force potential to it?
- What stabilizes a protein?
- Why does the surface area to volume ratio restrict cell size?
- What are the most recent applications of atomic force microscopy in protein research?
- What are the significant differences between the proteins of warm-blooded organisms and those of cold-blooded organisms?
- What is the evolutionary history of GPCRs?
- What are the best scientific papers on the physiology of E. coli in the laboratory environment, particularly on agar and in LB broth?
- How do copy number variations affect the error rate (both random and systematic) of protein synthesis?
- Do telomeres play any role in post-mitotic cells?
- How can one characterize the microenvironments of a cell?
- Akshari Gupta's answer to What are some of the best answers written in 2014 by Quorans who are not Top Writers?
- What sort of movements happen on bacterial membranes?
- Logan Collins' answer to Have we already discovered all the organelles in the cell?
- Logan Collins' answer to What are the types of giant cells?
- Logan Collins' answer to What are the advantages of the pET expression system over other vectors?
- What is the difference between I1, I2, I3, and I4 feed-forward loops?
- Sharlene Dong's answer to What are some examples of bifan motifs in cellular regulatory networks?
- Why does thiamine deficiency (mechanistically) lead to Korsakoff's syndrome?
- Edward Claro Mader's answer to How do I read an EEG?
- Edward Claro Mader's answer to Why did we evolve the ability to sleep?
- Korsakoff's syndrome
- Edward Claro Mader's answer to Neuroscience: Why does thiamine deficiency (mechanistically) lead to Korsakoff's syndrome?
- Sarang Nath's answer to How do you measure a chemical's propensity to intercalate DNA?
- Sarang Nath's answer to What is a selectively permeable membrane?
- Shreyas Krishnapura's answer to Imagine that you are a cell going through mitosis. What is your first-person account describing this process?
- Christopher VanLang's answer to Scientists (and science enthusiasts) of Quora: What is your personal "holy grail" of science?
- Stijn Hommes' answer to What are the advantages and disadvantages of taking more than the prescribed amount of antibiotics?
- Akshari Gupta's answer to What part of the cell is actually dividing in mitosis?
- Why is it so hard to develop Ras inhibitors?
- Does DNA taste sweet?
- What is a DNA vaccine?
- Alex Siegel's answer to What's the average size of a human protein (in kDa)?
- Alex Siegel's answer to How does IPTG induced gene expression work at a molecular level?
- Alex Siegel's answer to Why are most alpha helices in proteins right handed?
- Alex Siegel's answer to What exactly do zinc fingers do?
- Dan Holliday's answer to How come insects are smaller than most mammals?
- Shan Kothari's answer to What is the evolutionary history of the Venus flytrap?
- Bill Vanyo's answer to Has the law of biogenesis been disproven or downgraded to a theory?
- Tirumalai Kamala's answer to What is a DNA vaccine?"
- What problems in biology involve the collection and analysis of multi-terabyte data sets?
- What should a data scientist know about the gene expression data analysis?
- Is there mathematically intense work in cellular and molecular biology?
- How does a DNA microarray work?
- What is an "at home" genetic data analysis project?