forked from cbare/network_portal
-
Notifications
You must be signed in to change notification settings - Fork 0
/
use-cases.txt
36 lines (25 loc) · 1.18 KB
/
use-cases.txt
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
Use cases for Network Portal
============================
==How are these genes related?
==How are these genes regulated?
1) enter a set of genes into search box
2) get back matching genes, biclusters, functions & species
3) view network showing - gene membership, shared regulation, motifs
4) drill down into individual genes, motifs, regulators, biclusters
==Given a set of genes, what functions do they have?
==Given a regular, what does it regulate?
1) enter a regulator into search box
2) get back matching genes, biclusters, functions & species
3) click on regulator - get it's regulated genes (for each network?)
4) just show regulated biclusters?
==Given a regulator, what functions does it regulate?
==Given a function, what genes / regulons perform that function?
1) search for a function
2)
==find all possible motifs for a regulator?
Questions
=========
How do we want to narrow by species?
Do we want to compute functional enrichment for a set of biclusters? Or just one bicluster at a time?
Is it a goal to assign functions to unannotated genes or correct annotated functions?
Can we build promoter architectures from regular (non-ensemble) cMonkey? How should we explore by motif?