diff --git a/manuscript/paper.md b/manuscript/paper.md index afd851d..8eedd9e 100644 --- a/manuscript/paper.md +++ b/manuscript/paper.md @@ -38,9 +38,9 @@ affiliations: index: 1 - name: Centre for Epidemic Response and Innovation, CERI, University of Stellenbosch, Stellenbosch, South Africa index: 2 - - name: Yale University School of Medicine, New Haven, Connecticut, USA + - name: Yale University School of Medicine, New Haven, Connecticut, United States of America index: 3 - - name: Department of Global Health, University of Washington, Seattle, WA, USA + - name: Department of Global Health, University of Washington, Seattle, WA, United States of America index: 4 - name: University College Cork, Ireland index: 5 @@ -130,7 +130,7 @@ Genomic epidemiology and associated public health interventions entirely depend # Future prospects: -Many microorganisms have fragmented genes (exons separated by introns), overlapped genes or genes with frameshift events such as Influenza A with a segmented genome, however, at present the tool only supports single-segment genomes without other stated events. We plan to extend it to support complex gene and genome structures. We wish to report INDELs whose length is not a multiple of 3 and yet they are present in the same read and summation leads to a multiple of three. Furthermore, as the cost of sequencing continues to decrease and the capacity to sequence increases, we expect to see a further influx in the number of microbial genomes. To this effect, we intend to implement performance enhancements to reduce the batch analyses running time given a fairly large number of genomes. +Many microorganisms have fragmented genes (exons separated by introns), overlapping genes or genes with frameshift events such as Influenza A with a segmented genome, however, at present the tool only supports single-segment genomes without other stated events. We plan to extend it to support complex gene and genome structures. We wish to report INDELs whose length is not a multiple of 3 and yet they are present in the same read and summation leads to a multiple of three. Furthermore, as the cost of sequencing continues to decrease and the capacity to sequence increases, we expect to see a further influx in the number of microbial genomes. To this effect, we intend to implement performance enhancements to reduce the batch analyses running time given a fairly large number of genomes. # Acknowledgements