diff --git a/client/src/api/schema/schema.ts b/client/src/api/schema/schema.ts
index 7b032f8caa49..7e3cda1f61c4 100644
--- a/client/src/api/schema/schema.ts
+++ b/client/src/api/schema/schema.ts
@@ -13020,6 +13020,24 @@ export interface components {
             /** Total Disk Usage */
             total_disk_usage: number;
         };
+        /** UserUpdatePayload */
+        UserUpdatePayload: {
+            /**
+             * Active
+             * @description User is active
+             */
+            active?: boolean | null;
+            /**
+             * Preferred Object Store ID
+             * @description The ID of the object store that should be used to store new datasets in this history.
+             */
+            preferred_object_store_id?: string | null;
+            /**
+             * Username
+             * @description The name of the user.
+             */
+            username?: string | null;
+        };
         /** Visualization */
         Visualization: Record<string, never>;
         /** VisualizationSummary */
@@ -24966,7 +24984,7 @@ export interface operations {
         };
         requestBody: {
             content: {
-                "application/json": Record<string, never>;
+                "application/json": components["schemas"]["UserUpdatePayload"];
             };
         };
         responses: {
diff --git a/lib/galaxy/schema/schema.py b/lib/galaxy/schema/schema.py
index 9cdf22507164..e83c76edfef2 100644
--- a/lib/galaxy/schema/schema.py
+++ b/lib/galaxy/schema/schema.py
@@ -375,6 +375,12 @@ class DetailedUserModel(BaseUserModel, AnonUserModel):
     tags_used: List[str] = Field(default=..., title="Tags used", description="Tags used by the user")
 
 
+class UserUpdatePayload(Model):
+    active: Annotated[Optional[bool], Field(None, title="Active", description="User is active")]
+    username: Annotated[Optional[str], Field(None, title="Username", description="The name of the user.")]
+    preferred_object_store_id: Annotated[Optional[str], PreferredObjectStoreIdField]
+
+
 class UserCreationPayload(Model):
     password: str = Field(default=..., title="user_password", description="The password of the user.")
     email: str = UserEmailField
diff --git a/lib/galaxy/webapps/galaxy/api/users.py b/lib/galaxy/webapps/galaxy/api/users.py
index eb051f63ed97..d3d4ea4dcda4 100644
--- a/lib/galaxy/webapps/galaxy/api/users.py
+++ b/lib/galaxy/webapps/galaxy/api/users.py
@@ -8,7 +8,6 @@
 import re
 from typing import (
     Any,
-    Dict,
     List,
     Optional,
     Union,
@@ -61,6 +60,7 @@
     UserBeaconSetting,
     UserCreationPayload,
     UserDeletionPayload,
+    UserUpdatePayload,
 )
 from galaxy.security.validate_user_input import (
     validate_email,
@@ -674,13 +674,14 @@ def update(
         self,
         trans: ProvidesUserContext = DependsOnTrans,
         user_id: FlexibleUserIdType = FlexibleUserIdPathParam,
-        payload: Dict[Any, Any] = UserUpdateBody,
+        payload: UserUpdatePayload = UserUpdateBody,
         deleted: Optional[bool] = UserDeletedQueryParam,
     ) -> DetailedUserModel:
         deleted = deleted or False
         current_user = trans.user
         user_to_update = self.service.get_non_anonymous_user_full(trans, user_id, deleted=deleted)
-        self.service.user_deserializer.deserialize(user_to_update, payload, user=current_user, trans=trans)
+        data = payload.model_dump(exclude_unset=True)
+        self.service.user_deserializer.deserialize(user_to_update, data, user=current_user, trans=trans)
         return self.service.user_to_detailed_model(user_to_update)
 
     @router.delete(