diff --git a/.github/workflows/build.yml b/.github/workflows/build.yml
index 6a27543..06cc31c 100644
--- a/.github/workflows/build.yml
+++ b/.github/workflows/build.yml
@@ -14,7 +14,7 @@ jobs:
     strategy:
       matrix:
         fast_finish: [false]
-        python-version: [3.8]
+        python-version: [3.10]
   
     steps:
       - uses: actions/checkout@v2
@@ -31,7 +31,7 @@ jobs:
           curl -sSL https://install.python-poetry.org | python3 -
           pip install --upgrade pip
           pip install -e ".[docs, dev]"
-          pip install pyg_lib torch_scatter==2.1.1 torch_sparse torch_cluster torch_spline_conv -f https://data.pyg.org/whl/torch-2.0.0+cpu.html
+          install_pyg_dependencies
       
       - name: Build documentation
         run: |
diff --git a/pyproject.toml b/pyproject.toml
index c9f1c2e..2b97a81 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -50,6 +50,7 @@ pynvml = "*"
 scikit-misc = "*"
 opencv-python = "*"
 harmonypy = "*"
+loguru = "*"
 
 torch = {version = ">=2.0.0"}
 torchvision = {version = "*"}
@@ -85,4 +86,7 @@ dev = ["pytest", "pytest-cov", "papermill", "ipython", "jupyter", "parse", "nbfo
 [tool.pyright]
 include = ["scSLAT"]
 exclude = ["**/conda", "**/__pycache__", "**/.**"]
-ignore = ["resource/"]
\ No newline at end of file
+ignore = ["resource/"]
+
+[tool.poetry.scripts]
+install_pyg_dependencies = "scSLAT.utils:install_pyg_dep"
\ No newline at end of file
diff --git a/scSLAT/utils.py b/scSLAT/utils.py
index da41e75..2843477 100644
--- a/scSLAT/utils.py
+++ b/scSLAT/utils.py
@@ -2,10 +2,12 @@
 Miscellaneous utilities
 """
 import random
+from subprocess import run
 
 from pynvml import *
 from anndata import AnnData
 from typing import List, Optional, Union
+from loguru import logger
 
 import numpy as np
 import torch
@@ -96,4 +98,65 @@ def global_seed(seed: int) -> None:
     torch.manual_seed(seed)
     if torch.cuda.is_available():
         torch.cuda.manual_seed_all(seed)
-    print(f"Global seed set to {seed}.")
\ No newline at end of file
+    print(f"Global seed set to {seed}.")
+
+
+def install_pyg_dep(torch_version: str = None, cuda_version: str = None):
+    r"""
+    Automatically install PyG dependencies
+
+    Parameters
+    ----------
+    torch_version
+        torch version, e.g. 2.2.1
+    cuda_version
+        cuda version, e.g. 12.1
+    """
+    if torch_version is None:
+        torch_version = torch.__version__
+        torch_version = torch_version.split("+")[0]
+
+    if cuda_version is None:
+        cuda_version = torch.version.cuda
+
+    if torch_version < "2.0":
+        raise ValueError(f"PyG only support torch>=2.0, but get {torch_version}")
+    elif "2.0" <= torch_version < "2.1":
+        torch_version = "2.0.0"
+    elif "2.1" <= torch_version < "2.2":
+        torch_version = "2.1.0"
+    elif "2.2" <= torch_version < "2.3":
+        torch_version = "2.2.0"
+
+    if "cu" in cuda_version and not torch.cuda.is_available():
+        logger.warning(
+            "CUDA is not available, try install CPU version, but may raise error."
+        )
+        cuda_version = "cpu"
+    elif cuda_version >= "12.1":
+        cuda_version = "cu121"
+    elif "11.8" <= cuda_version < "12.1":
+        cuda_version = "cu118"
+    elif "11.7" <= cuda_version < "11.8":
+        cuda_version = "cu117"
+    else:
+        raise ValueError(f"PyG only support cuda>=11.7, but get {cuda_version}")
+
+    if torch_version == "2.2.0" and cuda_version == "cu117":
+        raise ValueError(
+            "PyG not support torch-2.2.* with cuda-11.7, please check https://pytorch-geometric.readthedocs.io/en/latest/install/installation.html"
+        )
+    if torch_version == "2.1.0" and cuda_version == "cu117":
+        raise ValueError(
+            "PyG not support torch-2.1.* with cuda-11.7, please check https://pytorch-geometric.readthedocs.io/en/latest/install/installation.html"
+        )
+    if torch_version == "2.0.0" and cuda_version == "cu121":
+        raise ValueError(
+            "PyG not support torch-2.0.* with cuda-12.1, please check https://pytorch-geometric.readthedocs.io/en/latest/install/installation.html"
+        )
+
+    logger.info(
+        f"Installing PyG dependencies for torch-{torch_version} and cuda-{cuda_version}"
+    )
+    cmd = f"pip install pyg_lib torch_scatter torch_sparse torch_cluster torch_spline_conv -f https://data.pyg.org/whl/torch-{torch_version}+{cuda_version}.html"
+    run(cmd, shell=True)