DESCRIPTION

Package: methylclock
Type: Package
Title: Chronological and gestational DNAm age estimation using different methylation-based clocks
Version: 0.8.2
Date: 2023-04-04
Authors@R: c( person("Dolors", "Pelegri-Siso", , "dolors.pelegri@isglobal.org", 
                      role = c("aut", "cre"), 
                      comment = c(ORCID = "0000-0002-5993-3003")),
              person("Juan R.", "Gonzalez", ,"juanr.gonzalez@isglobal.org", 
                     role = c("aut"), 
                     comment = c(ORCID = "0000-0003-3267-2146"))
              )
Description: This package allows to estimate chronological and gestational DNA methylation
       (DNAm) age as well as biological age using different methylation clocks.
       Chronological DNAm age (in years) : Horvath's clock, Hannum's clock, BNN, 
       Horvath's skin+blood clock, PedBE clock and Wu's clock.
       Gestational DNAm age : Knight's clock, Bohlin's clock, Mayne's clock and Lee's clocks.
       Biological DNAm clocks : Levine's clock and Telomere Length's clock.
biocViews: 
  DNAMethylation,
  BiologicalQuestion,
  Preprocessing,
  StatisticalMethod,
  Normalization
License: MIT + file LICENSE
Depends: 
  R (>= 3.6.0),
  devtools,
  quadprog
Imports: 
  Rcpp,
  dplyr, 
  impute, 
  PerformanceAnalytics,
  Biobase,
  tidyverse,
  tidyr,
  ggplot2, 
  gridExtra,
  ggpmisc, 
  ggpubr, 
  minfi, 
  planet,
  tibble,
  preprocessCore
Suggests: 
  RPMM,
  BiocStyle, 
  knitr, 
  rmarkdown
LinkingTo: Rcpp
Encoding: UTF-8
URL: https://github.com/isglobal-brge/methylclock
BugReports: https://github.com/isglobal-brge/methylclock/issues
LazyData: true
RoxygenNote: 7.2.2
VignetteBuilder: knitr