diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index a1b6123fe..f179ada20 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -177,7 +177,9 @@ jobs:
           - i686-unknown-linux-musl
           - armv7-unknown-linux-gnueabihf
           - aarch64-unknown-linux-gnu
-          - mips-unknown-linux-gnu
+          # Big-endian targets. See https://twitter.com/burntsushi5/status/1695483429997945092.
+          - powerpc64-unknown-linux-gnu
+          - s390x-unknown-linux-gnu
 
     steps:
     - uses: actions/checkout@v3