Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Refactor reported variant creators (for clinical interpretations) #169

Open
jtarraga opened this issue Jun 19, 2019 · 0 comments
Open

Refactor reported variant creators (for clinical interpretations) #169

jtarraga opened this issue Jun 19, 2019 · 0 comments
Assignees

Comments

@jtarraga
Copy link
Member

Currently, clinical interpretations rely on three reported variant creators according to the interpretation analysis (Tiering, TEAM or default). They are responsible of creating the reported events (per disease panel and transcript) for each variant. Basically, a reported event consists of a panel disease, a list of sequence ontology terms (consequence types), the role in cancer, the ACMG classification, the clinical significance and a tier. Only assigning the tier is analysis dependent, so we should merge that reported variant creators in one creator, and delegate the tier assignation to the interpretation analysis itself.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Projects
None yet
Development

No branches or pull requests

1 participant