diff --git a/pyproject.toml b/pyproject.toml
index d32d288..f76cce9 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -21,3 +21,7 @@ warn_unused_configs = true
 [[tool.mypy.overrides]]
 module = "nose.plugins.skip"
 ignore_missing_imports = true
+
+[build-system]
+requires = ["setuptools>=64.0", "cython>=3"]
+build-backend = "setuptools.build_meta"
diff --git a/setup.py b/setup.py
index 7c6ef26..a085fbf 100644
--- a/setup.py
+++ b/setup.py
@@ -75,5 +75,4 @@
         packages=["qcore", "qcore.tests"],
         package_data={"qcore": DATA_FILES},
         ext_modules=EXTENSIONS,
-        setup_requires=["Cython"],
     )