proportion of celltype has changed but AverageExpression of its marker gene didn't #9063
yulchen810
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Hi,
In my snRNA-seq data, the population of a celltype has increased significantly in group A compared to group B, but the AverageExpression of its marker gene didn't increase (and not in the differential expression genes), how to explain this?
If the population of one cell type increased, the total mRNA of it will also increase, qPCR of its gene marker can demonstrate that. But in snRNA-seq, is there other indicator for this?
Thank you!
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