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Upon using NormalizeData(seurat_object, normalization.method = "CLR"), the normalization takes place across features and the following dataset is obtained.
Could anyone please help me understand the mathematical calculations behind the CLR normalization. I have tried dividing feature counts by geometric mean and taking the natural log. However, I believe that I obtained totally different entries.
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I have this example dataset.
Upon using
NormalizeData(seurat_object, normalization.method = "CLR")
, the normalization takes place across features and the following dataset is obtained.Could anyone please help me understand the mathematical calculations behind the CLR normalization. I have tried dividing feature counts by geometric mean and taking the natural log. However, I believe that I obtained totally different entries.
Here is the screenshot of the procedure.
Any help would be appreciated.
Regards.
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