diff --git a/cores/arduino/stm32/usb/cdc/cdc_queue.h b/cores/arduino/stm32/usb/cdc/cdc_queue.h
index cd10ac2bc5..1ec58d02f0 100644
--- a/cores/arduino/stm32/usb/cdc/cdc_queue.h
+++ b/cores/arduino/stm32/usb/cdc/cdc_queue.h
@@ -53,8 +53,14 @@ extern "C" {
 #else
 #define CDC_QUEUE_MAX_PACKET_SIZE USB_FS_MAX_PACKET_SIZE
 #endif
-#define CDC_TRANSMIT_QUEUE_BUFFER_SIZE ((uint16_t)(CDC_QUEUE_MAX_PACKET_SIZE * 2))
-#define CDC_RECEIVE_QUEUE_BUFFER_SIZE ((uint16_t)(CDC_QUEUE_MAX_PACKET_SIZE * 3))
+#ifndef CDC_TRANSMIT_QUEUE_BUFFER_PACKET_NUMBER
+#define CDC_TRANSMIT_QUEUE_BUFFER_PACKET_NUMBER 2
+#endif
+#ifndef CDC_RECEIVE_QUEUE_BUFFER_PACKET_NUMBER
+#define CDC_RECEIVE_QUEUE_BUFFER_PACKET_NUMBER 3
+#endif
+#define CDC_TRANSMIT_QUEUE_BUFFER_SIZE ((uint16_t)(CDC_QUEUE_MAX_PACKET_SIZE * CDC_TRANSMIT_QUEUE_BUFFER_PACKET_NUMBER))
+#define CDC_RECEIVE_QUEUE_BUFFER_SIZE ((uint16_t)(CDC_QUEUE_MAX_PACKET_SIZE * CDC_RECEIVE_QUEUE_BUFFER_PACKET_NUMBER))
 
 typedef struct {
   uint8_t buffer[CDC_TRANSMIT_QUEUE_BUFFER_SIZE];
@@ -91,4 +97,4 @@ void CDC_ReceiveQueue_CommitBlock(CDC_ReceiveQueue_TypeDef *queue, uint16_t size
 }
 #endif
 
-#endif // __CDC_QUEUE_H
\ No newline at end of file
+#endif // __CDC_QUEUE_H