diff --git a/CHANGELOG.rst b/CHANGELOG.rst
index 9bdfab05b..8b2a0caa6 100644
--- a/CHANGELOG.rst
+++ b/CHANGELOG.rst
@@ -41,6 +41,8 @@ Changed
 
 - Don't perform invalid format check in Tarantool 2.10.4 and above.
 
+- Throw an error when using Tarantool 3.
+
 -------------------------------------------------------------------------------
 [2.8.1] - 2023-07-20
 -------------------------------------------------------------------------------
diff --git a/cartridge.lua b/cartridge.lua
index 6dd4d38bc..2d8e2d6ed 100644
--- a/cartridge.lua
+++ b/cartridge.lua
@@ -23,6 +23,7 @@ local http = require('http.server')
 local fiber = require('fiber')
 local socket = require('socket')
 local json = require('json')
+local tarantool_version = require('tarantool').version
 
 local rpc = require('cartridge.rpc')
 local auth = require('cartridge.auth')
@@ -317,6 +318,10 @@ local function cfg(opts, box_opts)
         disable_errstack = '?boolean',
     }, '?table')
 
+    if tarantool_version:sub(1, 2) == '3.' then
+        return nil, CartridgeCfgError:new("Unsupported Tarantool version " .. tarantool_version)
+    end
+
     if opts.enable_sychro_mode ~= nil then
         opts.enable_synchro_mode = opts.enable_sychro_mode
         log.warn('enable_sychro_mode is deprecated. Use enable_synchro_mode instead')