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<!doctype html>
<html lang="en">
<head>
<meta charset="utf-8">
<title>What is LORIS and why does our life depend on it?</title>
<meta name="description" content="A framework for easily creating beautiful presentations using HTML">
<meta name="author" content="Hakim El Hattab">
<meta name="apple-mobile-web-app-capable" content="yes" />
<meta name="apple-mobile-web-app-status-bar-style" content="black-translucent" />
<meta name="viewport" content="width=device-width, initial-scale=1.0, maximum-scale=1.0, user-scalable=no, minimal-ui">
<!-- The important Javascript libraries -->
<link rel="stylesheet" href="css/reveal.css">
<link rel="stylesheet" href="css/theme/black.css" id="theme">
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</script>
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<script src="lib/js/html5shiv.js"></script>
<![endif]-->
</head>
<body>
<div class="reveal">
<!-- Any section element inside of this container is displayed as a slide -->
<div class="slides">
<!-- Title slide -->
<section>
<section>
<h1>LORIS</h1>
<h3><font color='yellow'>To boldly go where no ACE researcher has apparently gone before...</font></h3>
<p>ACE Lab Meeting - February 26th, 2016</p>
<p><font color='pink'>Samir Das & Zia Mohades</font></p>
</section>
<section>
<img src="images/Zia_Samir.png">
</section>
</section>
<!-- Today's talk -->
<section>
<h2><font color="yellow">Today's talk</font></h2>
<p class="fragment roll-in"> 1 - What is LORIS and how it was developed?</p>
<p class="fragment roll-in"> 2 - What data sharing projects are coordinated by MCIN?</p>
<p class="fragment roll-in"> 3 - How LORIS can facilitate your own research needs?</p>
</section>
<!-- What is LORIS? -->
<section>
<h2>What is LORIS?</h2>
<table class="reveal">
<tr>
<td width="50%" style="vertical-align: middle">
<p><small> “LORIS is a modular and extensible web-based data management system that integrates all aspects of a multi-center study: from heterogeneous data acquisition (imaging, clinical, behavior, genetics) to storage, processing and ultimately dissemination.”</small></p>
</td>
<td>
<img src="images/LORIS_paper.png">
</td></tr></table>
</section>
<section>
<section><a href="http://slides.com" target="_blank">
<h2><font color= "yellow">History of LORIS - The Creator</font></h2>
<img src="images/dario.jpg">
<!-- <iframe width="1152" height="698" src="http://play.starwars.com/html5/starwars_crawlcreator/?cid=56985df4e4b0ea41f9792392" frameborder="1" scrolling="no"></iframe>
-->
</section>
<section><a href="http://slides.com" target="_blank">
<h2><a href="http://www.starwars.com/games-apps/star-wars-crawl-creator/?cid=56992fffe4b054a12a013908" target="_blank"><font color= "yellow">The nice guy</font></a></h2>
<img src="images/Matt.png">
</section>
<section><a href="http://slides.com" target="_blank">
<h2><a href="http://www.starwars.com/games-apps/star-wars-crawl-creator/?cid=56992fffe4b054a12a013908" target="_blank"><font color= "yellow">Core Developer</font></a></h2>
<img src="images/Harlap.png">
</section>
<section><a href="http://slides.com" target="_blank">
<h2><a href="http://www.starwars.com/games-apps/star-wars-crawl-creator/?cid=56992fffe4b054a12a013908" target="_blank"><font color= "yellow">Lab Manager</font></a></h2>
<img src="images/Reza.png">
</section>
<section><a href="http://slides.com" target="_blank">
<h2><a href="http://www.starwars.com/games-apps/star-wars-crawl-creator/?cid=56992fffe4b054a12a013908" target="_blank"><font color= "yellow">Prison Break</font></a></h2>
<img src="images/Samir_bad.png">
</section>
<section><a href="http://slides.com" target="_blank">
<h2><a href="http://www.starwars.com/games-apps/star-wars-crawl-creator/?cid=56992fffe4b054a12a013908" target="_blank"><font color= "yellow">My jailbreak accomplice</font></a></h2>
<img src="images/Marc_bad.png">
</section>
<section><a href="http://slides.com" target="_blank">
<h2><a href="http://www.starwars.com/games-apps/star-wars-crawl-creator/?cid=56992fffe4b054a12a013908" target="_blank"><font color= "yellow">The Warden</font></a></h2>
<img src="images/Pierre_bad.png">
</section>
<section><a href="http://slides.com" target="_blank">
<h2><a href="http://www.starwars.com/games-apps/star-wars-crawl-creator/?cid=56992fffe4b054a12a013908" target="_blank"><font color= "yellow">Everybody Loves Zia</font></a></h2>
<img src="images/Zia_India.png">
</section>
</section>
<section>
<h2><a href="https://demo.loris.ca">LORIS Demo</a></h2>
</section>
<!-- LORIS globally -->
<section data-background="images/LORIS_global.png">
<h1><font color ="blue">LORIS globally</font></h1>
</section>
<!-- LORIS Projects -->
<section>
<!-- NIHPD -->
<section>
<img src="images/NIHPD_logo.jpg">
<table class="reveal">
<tr>
<td width="45%" style="vertical-align: middle">
<img src="images/NIHPD_paper.png">
</td>
<td width="30%" style="vertical-align: middle">
<img src="images/MRI_images_several.jpg">
</td>
<td width="30%" style="vertical-align: middle">
<p><small>
<ul>
<li>8 year study</li>
<li>Longitudinal data</li>
<li>532 subjects</li>
<li>8000 distinct variables</li>
<li>37000 individual assessments</li>
<li>T1, T2, PD, DTI</li>
<li>Spectroscopy</li>
<li>∼3TB of imaging data</li>
<li>2000 MRI acquisitions</li>
</ul>
</small></p>
</td>
</tr></table>
</section>
<!-- IBIS -->
<section>
<img src="images/IBIS.png">
<table class="reveal">
<tr>
<td width="45%" style="vertical-align: middle">
<img src="images/IBIS_paper.png">
</td>
<td width="30%" style="vertical-align: middle">
<img src="images/IBIS_image.png">
</td>
<td width="30%" style="vertical-align: middle">
<p><small>
<ul>
<li>Infant brain development in autism</li>
<li>3000+ scans</li>
<li>700+ subjects</li>
<li>7000 distinct variables</li>
<li>150,000+ individual assessments</li>
<li>T1, T2, DTI, BOLD</li>
<li>∼5 TBs of imaging data</li>
<li>Genetic/biospecimen data</li>
</ul>
</small></p>
</td>
</tr></table>
</section>
<!-- BigBrain -->
<section>
<table class="reveal">
<h2>BigBrain</h2>
<tr>
<td width="50%" style="vertical-align: middle">
<img src="images/BigBrain.png">
</td>
<td width="50%" style="vertical-align: middle">
<img src="images/BigBrain_paper.png">
</td>
</tr></table>
</section>
<!-- OMEGA - small pilot, interest has spiked -->
<section>
<table class="reveal">
<h2>OMEGA</h2>
<tr>
<td width="50%" style="vertical-align: middle">
<img src="images/OMEGA.png">
</td>
<td width="50%" style="vertical-align: middle">
<p><small>
<ul>
<li>The Open MEG Archive</li>
<li>First open MEG data repository</li>
<li>Growing number of scans</li>
<li>Associated structural data</li>
<li>Interest has spiked lately</li>
</ul>
</small></p>
</td>
</tr></table>
</section>
<!-- MAVAN, Ludmer Centre -->
<section>
<table class="reveal">
<h2>MAVAN and the Ludmer Centre</h2>
<tr>
<td width="50%" style="vertical-align: middle">
<img src="images/OMEGA.png">
</td>
<td width="50%" style="vertical-align: middle">
<p><small>
<ul>
<li>MAVAN</li>
<li>Maternal Adversity Vulnerability And NeuroDevelopement </li>
<li>Behavioral, Imaging and Genomics</li>
<li>Key project for the Ludmer Centre</li>
<li>Examining acute and chronic stressors on early childhood developement</li>
</ul>
</small></p>
</td>
</tr></table>
</section>
<!-- MNI Open Science -->
<section>
<h2>Open Science</h2>
<table class="reveal">
<tr>
<td width="50%" style="vertical-align: middle">
<p><small>
<ul>
<li>Comprises the Biobank and Imaging Centre</li>
<li>LORIS is slated the platform for both</li>
<li>Data sharing at the MNI will be intergral to research</li>
<li>Designed to reduce duplication and make research more efficient</li>
</ul>
</small></p>
<p><small><font color="yellow">“We’re doing a really shitty job." -- Guy Rouleau </font></small></p>
</td>
<td>
<img src="images/Open_science.png">
</td></tr></table>
</section>
<!-- Others? PreventAD, ADNI, ABIDE, GEN-R, PERFORM -->
<section>
<h2><font color="yellow">Other possible datasets</font></h2>
<p class="fragment roll-in">PreventAD</p>
<p class="fragment roll-in">ADNI?</p>
<p class="fragment roll-in">ABIDE?</p>
<p class="fragment roll-in">Gen-R?</p>
<p class="fragment roll-in">PERFORM?</p>
<p class="fragment roll-in">Others...?</p>
</section>
</section>
<!-- How can LORIS be useful for the MCIN? -->
<section>
<section>
<h2><font color="yellow">How can LORIS be useful to you?</font></h2>
</section>
<section>
<h2><font color="yellow">Testimonials</font></h2>
<p class="fragment roll-in">"You don't understand... LORIS saved our lives ... We could share our data anywhere. LORIS makes it really hard to share incorrect data. The quality control data is right there. You can share the QC... it's so well QCed"<font color="yellow"> -- Angelina Paolozza (NeuroDevenet, 2015)</font></p>
</section>
<section>
<h2><font color="yellow">Key Features for the lab</font></h2>
<p class="fragment roll-in">Organize your data</p>
<p class="fragment roll-in">Enable Quality Control</p>
<p class="fragment roll-in">Easy data sharing</p>
<p class="fragment roll-in">Provenance capture</p>
<p class="fragment roll-in">Facilitate image visualization</p>
<p class="fragment roll-in">Summary statistics</p>
<p class="fragment roll-in">Facilitate statistical analysis</p>
<p class="fragment roll-in">Linking your data across modalities</p>
<p class="fragment roll-in">Online Data Querying</p>
</section>
<section>
<h2><font color="yellow">Additional Features</font></h2>
<p class="fragment roll-in">Centralized data repository</p>
<p class="fragment roll-in">Download data from one place</p>
<p class="fragment roll-in">Centralized Document Repoistory</p>
<p class="fragment roll-in">Backup your data</p>
<p class="fragment roll-in">Consent is factored in</p>
<p class="fragment roll-in">Anonimyzed automatically online</p>
<p class="fragment roll-in">Raw data can be accessed (e.g. DICOM archiver)</p>
<p class="fragment roll-in">Tablet Friendly - Survey module</p>
</section>
<section>
<h2><font color="yellow">Data Sharing Initiatives</font></h2>
<p>
<p class="fragment roll-in">Public Data Repositories</p>
<p class="fragment roll-in">Collaborative Data releases</p>
<p class="fragment roll-in">CBRAIN hooks</p>
<p class="fragment roll-in">Ontologicial standardization (e.g. BIDS)</p>
<p class="fragment roll-in">External Provenance (e.g. NIDM)</p>
<p class="fragment roll-in">Interoperability with other competitors</p>
<p class="fragment roll-in">Open Science at the MNI</p>
</section>
</section>
<section>
<h2><font color="yellow">LORIS developement: Please give us your feedback.</font></h2>
<img src="images/Lewis.png">
</section>
<!-- Case example: CCNA -->
<section>
<table class="reveal">
<h2><a href ="https://docs.google.com/presentation/d/1y_4X5qaqYOfkdKvce4E5XJtG4BSxq0bG9M2-DrjijBs/edit#slide=id.p4">CCNA Case Example</a></h2>
<tr>
<td width="50%" style="vertical-align: middle">
<img src="images/Zia.png">
</td>
<td width="50%" style="vertical-align: middle">
<p><small>
<ul>
<li>Canadian Consortium for Neurodegeration in Aging</li>
<li>Pan Canadian Study</li>
<li>$35 million study</li>
<li>More than 30 sites</li>
<li>Important project for this lab!</li>
</ul>
</small></p>
</td>
</tr></table>
</section>
<section data-transition="slide" data-background="#87CEEB" data-background-transition="zoom">
<img src="images/Royal_vic.png">
<h4>Acknowledgements</h4>
<p><small><font color="black">Alan Evans, Alex Zijdenbos, Reza Adalat, Penelope Kostopoulos, Louis Collins, Vladimir Fonov, Marc Rousseau, Tarek Sherif, Pierre Rioux, Nic Kassis, Leigh MacIntyre, Claude Lepage, Ilana Leppert, Carolina Makowski, Natasha Beck, Tristan Glatard, Bert Vincent, Lindsay Lewis, Najma Mahani, Elodie Portales-Casamar, Alden Woodward, Sylvain Milot, Jean Francois Malouin & Sylvain Baillet</font></small></p>
<p><small> <font color="white">LORIS Developers: </font><font color="black"> Dario Vins, Jonathan Harlap, Matt Charlet, Andrew Corderey, Sebastian Muehlboeck, David Brownlee, Zia Mohaddes, David MacFarlane, Cecile Madjar, Mia Petkova, Christine Rogers, Rathi Gnanasekaran, Justin Kat, Nicolas Brossard, Tara Campbell, Jordan Stirling, Daniel Kroetz, Ted Strauss, Young-vin Nah, Shipra Agarwal, Pierre-Emmaunel, Martin Weiss, Ayan Sengupta, Olga Tsibulevskaya, Nicolas St. George, Justin Leong, Mathieu Desrosiers, Gregory Luneau, Mouna Safi-Harab, Tom Beaudry, Santiago Paiva, Shen Wang and John Saigle</font></small> </p>
</section>
</div>
</div>
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