Skip to content

Scripts to create a phased reference panel from 1kGP for imputation with GLIMPSE

License

Notifications You must be signed in to change notification settings

Danko-Lab/GLIMPSE2_setup

Folders and files

NameName
Last commit message
Last commit date

Latest commit

 

History

15 Commits
 
 
 
 
 
 
 
 
 
 
 
 

Repository files navigation

GLIMPSE2_setup

This repo contains a snakemake pipeline to create a phased reference panel from 1kGP for imputation with GLIMPSE2. This pipeline follows their tutorial and use the most recent high coverage integrated phased panel from 1kGP.

Requirements

Software requirements are detailed in the conda environment file (spec/snakemake.yml). Paths to the base directory where everything will be downloaded/written and to GLIMPSE should be set by editing spec/file_spec.json (by default, this will be written to a subdirectory outputs where this repo is downloaded). GLIMPSE uses genetic maps to help decide how to chunk the genome to. The install path for GLIMPSE and parallel must be provided in the spec file.

Note that the X chromosome is bugged, and I have not yet figured out how to fix it. For now, I am just excluding it entirely (both non-PAR and the two PARs).

About

Scripts to create a phased reference panel from 1kGP for imputation with GLIMPSE

Resources

License

Stars

Watchers

Forks

Releases

No releases published

Packages

No packages published