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Bachmann_MSB2011
ladlung edited this page Jun 3, 2015
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Reference: Bachmann et al. Division of Labor by Dual Feedback Regulators Controls JAK2/STAT5 Signaling over Broad Ligand Range. Molecular Systems Biology 516, 7, 2011.
Folder: /Examples/Bachmann_MSB2011
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Facts: The model contains 542 data points, 113 free parameters and 24 experimental conditions.
Figure: Shows only parts of the data.
- Installation and system requirements
- Setting up models
- First steps
- Advanced events and pre-equilibration
- Computation of integration-based prediction bands
- How is the architecture of the code and the most important commands?
- What are the most important fields of the global variable ar?
- What are the most important functions?
- Optimization algorithms available in the d2d-framework
- Objective function, likelhood and chi-square in the d2d framework
- How to set up priors?
- How to set up steady state constraints?
- How do I restart the solver upon a step input?
- How to deal with integrator tolerances?
- How to implement a bolus injection?
- How to implement washing and an injection?
- How to implement a moment ODE model?
- How to run PLE calculations on a Cluster?