Create find_proxy function for local outcome
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### Summary This PR adds a local proxy SNP search function to the TwoSampleMR package. This function allows users to find proxy SNPs locally with or without relying on external databases, enhancing the package's usability and functionality. ### Details - Added a new script `find_proxy.R` under the `R` directory. - Implemented a function to search for proxy SNPs for local data, which is not available in the current tsmr package. - Updated example use in `find_proxy.R`, which can easily be used in line with tsmr pipeline. ### Motivation Finding proxy SNPs is a critical step in many MR analyses. By providing a local search function, we can support users who have specific datasets or need offline capabilities. ### Testing Tested the function with several example datasets to ensure accuracy and performance, which are documented in the comments within the added script. ### Additional Notes First of all, totally big fan of your team and the great work you do. This PR adds only one file, `find_proxy.R`, under the `R` directory. This should help the maintainer easily check and review the changes. If this idea is accepted but requires more details, please feel free to contact me via GitHub. I am happy to contribute further to the TwoSampleMR package.
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Summary
This PR adds a local proxy SNP search function to the TwoSampleMR package. This function allows users to find proxy SNPs locally with or without relying on external databases, enhancing the package's usability and functionality.
Details
find_proxy.Runder theRdirectory.find_proxy.R, which can easily be used in line with tsmr pipeline.Motivation
Finding proxy SNPs is a critical step in many MR analyses. By providing a local search function, we can support users who have specific datasets or need offline capabilities.
Testing
Tested the function with several iv datasets in our case to ensure accuracy and performance, which are documented in the comments within the added script.
Additional Notes
First of all, totally big fan of your team and the great work you do. This PR adds only one file,
find_proxy.R, under theRdirectory. This should help the maintainer easily check and review the changes. If this idea is accepted but requires more details, please feel free to contact me via GitHub. I am happy to contribute further to the TwoSampleMR package.