Codesets and key variable definitions for study "Using Electronic Health Record Data to Evaluate Kidney Function Decline in Children with Chronic Kidney Disease"
| Codeset name and link | Description |
|---|---|
| rx_hypertension.csv | Anti-hypertensive medications |
| dx_glomerular_disease.csv | Glomerular disease diagnoses |
| dx_hypertension.csv | Hypertension diagnoses |
| dx_cancer.csv | Cancer diagnoses |
| dx_pmca_codeset.csv | Pediatric Medical Complexity Algorithm (PMCA) diagnosis codeset, adapted from Simon et al 2014 |
| lab_urine_protein_qual.csv | Qualitative urine protein lab measurements |
| height.csv | Height measurement |
| lab_serum_creatinine.csv | Serum creatinine lab measurements |
| px_kidney_transplant.csv | Kidney transplant procedures |
| px_dialysis.csv | Dialysis procedures |
| nephrology.csv | Nephrology specialty |
| kidney_biopsy | Kidney-biopsy related procedure and diagnosis codes |
- Hypertension: Hypertension was defined by the presence of a diagnosis code associated with at least two physician visits (Inpatient, Outpatient, or ED visits) within two years of cohort entrance.
- Proteinuria: Proteinuria was defined as having at least one urinalysis with at least 1+ proteinuria within two years of cohort entrance.
- Long-term dialysis: Long-term dialysis was defined as occurrence of 2 dialysis codes separated by at least 90 days
- Chronic disease burden: For chronic disease burden, the numeric count of body systems with chronic conditions in the three years prior to cohort entrance using ICD9/10 codes as specified by the Pediatric Medical Complexity Algorithm (PMCA); the PMCA count was filtered to exclude renal and genitourinary disease from the count.
- Glomerular disease: two occurrences of glomerular diagnosis codes OR one occurrence of a glomerular diagnosis code AND a native kidney biopsy.
- Malignancy: at least two physician visits (Inpatient, Outpatient, or ED visits) on different days at which at least one diagnosis code for malignancy was used.