The goal of celltalker is to infer putative ligand and receptor interactions from single-cell RNAseq data. Briefly, celltalker seeks to evaluate cell-cell communication based on expression of ligands and receptors within and between clusters of cells across experimental groups.
You can install the development version of celltalker from github using devtools:
library(devtools)
install_github("arc85/celltalker")
library(celltalker)
For more information and the celltalker vignette, check out the celltalker website https://arc85.github.io/celltalker/.