novoSpaRc - de novo Spatial Reconstruction of Single-Cell Gene Expression

novoSpaRc predicts locations of single cells in space by solely using single-cell RNA sequencing data. An existing reference database of marker genes is not required, but significantly enhances performance if available.

novoSpaRc accompanies the following publication:

Gene Expression Cartography

M. Nitzan, N. Karaiskos, N. Friedman, N. Rajewsky

Nature (2019)

Read the documentation and the tutorial for more information.