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Drug Central Ingest #457

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putmantime opened this issue May 11, 2023 · 4 comments
Open

Drug Central Ingest #457

putmantime opened this issue May 11, 2023 · 4 comments

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@putmantime
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We will extract associations from DrugCentral including “Indication”, “ContraIndication”, “Adverse Event” and “Off-Label Use” relationships between drugs and diseases.

We need to extract the required data from DrugCentral’s Postgres Database. Drug entities in DrugCentral have a variety of identifiers, such as from RxNorm, CAS, InChIKey, etc.

We will need to collaborate with DrugCentral to decide on faceting, thresholds and query design.

@justaddcoffee
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nb: @caufieldjh wrote some code to extract stuff from drug central's sql dumps for KG-IDG, see here

@caufieldjh
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ah, @justaddcoffee got there first, I was just about to post that

Would be happy to chat about DrugCentral specifics

@monicacecilia
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Dear @justaddcoffee @caufieldjh @kevinschaper, was there a conversation about this? Was it resolved?

@caufieldjh
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This was not resolved.
It's worth noting that the obo-db-ingest project also has some pre-transformed DrugCentral serializations - https://github.com/biopragmatics/obo-db-ingest/tree/main/export/drugcentral
These don't cover as much detail as the current KG-IDG ingest (e.g., KG-IDG includes details like FDA approval status).
So some decision on use case would be helpful here.

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4 participants