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config: update phylop and phastcons conservation scores to 470 way
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imedina committed Dec 28, 2023
1 parent 79726a0 commit f85a5c6
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Showing 2 changed files with 8 additions and 7 deletions.
3 changes: 2 additions & 1 deletion cellbase-core/src/main/resources/configuration.yml
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Expand Up @@ -109,9 +109,10 @@ download:
host: https://ftp.ebi.ac.uk/pub/databases/interpro/current_release/release_notes.txt
conservation:
host: https://hgdownload.cse.ucsc.edu/goldenPath/
version: "2022-08-30"
gerp:
host: http://ftp.ensembl.org/pub/release-110/compara/conservation_scores/91_mammals.gerp_conservation_score/gerp_conservation_scores.homo_sapiens.GRCh38.bw
version: "2023-04-22"
version: "2023-05-17"
clinvar:
# host: https://ftp.ncbi.nlm.nih.gov/pub/clinvar/xml/ClinVarFullRelease_2021-07.xml.gz
# host: https://ftp.ncbi.nlm.nih.gov/pub/clinvar/xml/ClinVarFullRelease_2022-02.xml.gz
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Original file line number Diff line number Diff line change
Expand Up @@ -115,16 +115,16 @@ public List<DownloadFile> downloadConservation() throws IOException, Interrupted
List<String> phastconsUrls = new ArrayList<>(chromosomes.length);
List<String> phyloPUrls = new ArrayList<>(chromosomes.length);
for (String chromosome : chromosomes) {
String phastConsUrl = url + "/phastCons100way/hg38.100way.phastCons/chr" + chromosome
+ ".phastCons100way.wigFix.gz";
String phastConsUrl = url + "/phastCons470way/hg38.470way.phastCons/chr" + chromosome
+ ".phastCons470way.wigFix.gz";
downloadFiles.add(downloadFile(phastConsUrl, conservationFolder.resolve("phastCons")
.resolve("chr" + chromosome + ".phastCons100way.wigFix.gz").toString()));
.resolve("chr" + chromosome + ".phastCons470way.wigFix.gz").toString()));
phastconsUrls.add(phastConsUrl);

String phyloPUrl = url + "/phyloP100way/hg38.100way.phyloP100way/chr" + chromosome
+ ".phyloP100way.wigFix.gz";
String phyloPUrl = url + "/phyloP470way/hg38.470way.phyloP470way/chr" + chromosome
+ ".phyloP470way.wigFix.gz";
downloadFiles.add(downloadFile(phyloPUrl, conservationFolder.resolve("phylop")
.resolve("chr" + chromosome + ".phyloP100way.wigFix.gz").toString()));
.resolve("chr" + chromosome + ".phyloP470way.wigFix.gz").toString()));
phyloPUrls.add(phyloPUrl);
}
String gerpUrl = configuration.getDownload().getGerp().getHost();
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