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  • National Medical Research Center for Obstetrics, Gynecology and Perinatology
  • Moscow
  • 17:24 (UTC +03:00)

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wwoskie/README.md

Aleksandr Voskoboinikov

I am an aspiring bioinformatician, currently undergoing advanced training at the Bioinformatics Institute. A graduate of Lomonosov Moscow State University in field of biology, with wet lab background. Passionate about developing better tools for bioinformatics and routine automation.

Research experience

Bioinformatics institute project: Pipeline for Loss of heterozygosity regions in exome and genome sequencing data

Currently our team developing pipeline for loss of heterozygosity detection HaploGone

MSc thesis: HIV-1 variability and antiretroviral therapy resistance mutations in the Russian Federation

Assisted in development of novel test system for HIV-1 detection. Performed Sanger sequencing and antiretroveral drug resistance prediction with SierraPy and sierra-local tools

BSc thesis: Effects of hypoxia-inducible factor 1α on immune activation in human atherosclerotic plaques ex vivo

Investigated cytotoxicity of PX-478 (HIF-1α inhibitor) and CoCl2 (HIF-1α activator) and their effect on immunoactivation in human ex-vivo atherosclerotic plaques. Extracted peripheral blood mononuclear cells (PBMC). Performed PBMC and explant short-term hypoxic cultivation.

Skills

Software development

  • Python: numpy, pandas, seaborn, matplotlib, plotly, sklearn, folium, geopandas, django basics
  • R basics: ggplot2, ggtree
  • Other: git + GitHub, Docker basics, Markdown, LaTeX, HTML + CSS basics
  • Tools: VS-code, Jupyter, RStudio, Overleaf

Machine Learning

Classic ML models (KNN, Kmeans, decision trees, random forest, ensembles) and basic ML concepts

Other

Languages:

  • English: Upper-Intermediate (B2)
  • Russian: Native

GitHub Stats

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  1. HaploGone HaploGone Public

    A tool for loss of heterozygosity (LOH) detection

    Jupyter Notebook 3 1

  2. YABT YABT Public

    YABT: yet another bioinformatic tool

    Python

  3. BI_ML_2024 BI_ML_2024 Public

    Homeworks for BI ML course

    Jupyter Notebook

  4. Phylogenetics_BI_2024 Phylogenetics_BI_2024 Public

    Jupyter Notebook