bam-quality-filter NOMe-seq

[sherryxuePKU]

Hello, I wonder if methylpy can filter reads by the methylation level of HCH. Because I have some NOMe-seq data，however they appeared to have low bisulfite conversion rate. I want to filter the genomic reads by their mHCH, not mCH. By the way, it may be helpful to make mehylpy bam-quality filter command able to filter by a user-selected type of C?

[yupenghe]

Thanks for the suggestion. Unfortunately, this feature is not currently supported by methylpy yet and it is not trivial to implement. I cannot promise that this feature will be available in a short period of time.

[sherryxuePKU]

@yupenghe Thanks for your reply! I'm in no hurry to use this function. BTW, methylpy is very useful in my data~