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add_dysgu_sarek #1590

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26 changes: 26 additions & 0 deletions conf/modules/dysgu.config
Original file line number Diff line number Diff line change
@@ -0,0 +1,26 @@
/*
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Config file for defining DSL2 per module options and publishing paths
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Available keys to override module options:
ext.args = Additional arguments appended to command in module.
ext.args2 = Second set of arguments appended to command in module (multi-tool modules).
ext.args3 = Third set of arguments appended to command in module (multi-tool modules).
ext.prefix = File name prefix for output files.
ext.when = When to run the module.
----------------------------------------------------------------------------------------
*/

// DYSGU

process {
withName: 'DYSGU' {
ext.args = { params.wes ? "--exome" : '' }
ext.prefix = { "${meta.id}.dysgu" }
publishDir = [
mode: params.publish_dir_mode,
path: { "${params.outdir}/variant_calling/dysgu/${meta.id}" },
pattern: "*.{vcf.gz,vcf.gz.tbi}"
]
}
}
13 changes: 13 additions & 0 deletions docs/output.md
Original file line number Diff line number Diff line change
Expand Up @@ -45,6 +45,7 @@ The pipeline is built using [Nextflow](https://www.nextflow.io/) and processes d
- [Structural Variants](#structural-variants)
- [Manta](#manta)
- [TIDDIT](#tiddit)
- [DYSGU](#dysgu)
- [Sample heterogeneity, ploidy and CNVs](#sample-heterogeneity-ploidy-and-cnvs)
- [ASCAT](#ascat)
- [CNVKit](#cnvkit)
Expand Down Expand Up @@ -639,6 +640,18 @@ It is optimized for analysis of germline variation in small sets of individuals

</details>

#### DYSGU

[DYSGU](https://github.com/kcleal/dysgu) dysgu (pronounced duss-key) is a set of command line tools and python-API, for calling structural variants using paired-end or long read sequencing data. For further reading and documentation see the [DYSGU manual](https://github.com/kcleal/dysgu/blob/master/README.rst).

<details markdown="1">
<summary>Output files for normal samples</summary>

**Output directory: `{outdir}/variantcalling/dysgu/<sample>/`**

- `<sample>.dysgu.vcf.gz` and `<sample>.dysgu.vcf.gz.tbi`
- VCF with tabix index containing SV calls

### Sample heterogeneity, ploidy and CNVs

#### ASCAT
Expand Down
5 changes: 5 additions & 0 deletions modules.json
Original file line number Diff line number Diff line change
Expand Up @@ -139,6 +139,11 @@
"installed_by": ["modules"],
"patch": "modules/nf-core/dragmap/hashtable/dragmap-hashtable.diff"
},
"dysgu": {
"branch": "master",
"git_sha": "c27498285a0beca2239b395cf88129c586a837fc",
"installed_by": ["modules"]
},
"ensemblvep/download": {
"branch": "master",
"git_sha": "3db4f8488315cd7d7cf3fcb64251f6603210e831",
Expand Down
4 changes: 2 additions & 2 deletions modules/nf-core/deepvariant/main.nf

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2 changes: 1 addition & 1 deletion modules/nf-core/dragmap/align/main.nf

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7 changes: 7 additions & 0 deletions modules/nf-core/dysgu/environment.yml

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56 changes: 56 additions & 0 deletions modules/nf-core/dysgu/main.nf

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68 changes: 68 additions & 0 deletions modules/nf-core/dysgu/meta.yml

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96 changes: 96 additions & 0 deletions modules/nf-core/dysgu/tests/main.nf.test

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75 changes: 75 additions & 0 deletions modules/nf-core/dysgu/tests/main.nf.test.snap

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